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Illumina Body Map 2, young vs old

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Results for NKX3-1

Z-value: 0.18

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Transcription factors associated with NKX3-1

Gene Symbol Gene ID Gene Info
NKX3-1
ENSG00000167034.9 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-1hg19_v2_chr8_-_23540402_23540466-0.271.4e-01Click!

Activity profile of NKX3-1 motif

Sorted Z-values of NKX3-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_109569155 2.10 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr12_-_54978086 1.93 ENST00000553113.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr17_-_55911970 1.76 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr2_-_102003987 1.74 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr2_-_179567206 1.59 ENST00000414766.1
TTN
titin
chr4_+_159131596 1.57 ENST00000512481.1
TMEM144
transmembrane protein 144
chr19_-_42931567 1.57 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr4_+_159131630 1.54 ENST00000504569.1
ENST00000509278.1
ENST00000514558.1
ENST00000503200.1
TMEM144
transmembrane protein 144
chr4_-_46126093 1.51 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr4_+_159131346 1.46 ENST00000508243.1
ENST00000296529.6
TMEM144
transmembrane protein 144
chr10_-_98116912 1.43 ENST00000536387.1
OPALIN
oligodendrocytic myelin paranodal and inner loop protein
chr14_-_39417410 1.43 ENST00000557019.1
ENST00000556116.1
ENST00000554732.1
LINC00639
long intergenic non-protein coding RNA 639
chr6_-_123958141 1.42 ENST00000334268.4
TRDN
triadin
chr1_+_171217622 1.38 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr1_-_216978709 1.30 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr10_-_27529486 1.21 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr19_-_12708113 1.17 ENST00000440366.1
ZNF490
zinc finger protein 490
chr6_+_80129989 1.16 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr1_+_171217677 1.15 ENST00000402921.2
FMO1
flavin containing monooxygenase 1
chr5_-_138211051 1.13 ENST00000518785.1
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr6_-_123958111 1.13 ENST00000542443.1
TRDN
triadin
chr6_-_127780510 1.10 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr11_+_65266507 1.05 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr9_-_73477826 1.04 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr14_-_39417473 1.00 ENST00000553932.1
LINC00639
long intergenic non-protein coding RNA 639
chr7_+_107301447 0.98 ENST00000440056.1
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr14_-_74551096 0.95 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr11_-_19223523 0.95 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr20_-_56286479 0.91 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr17_+_48610074 0.89 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr9_+_706842 0.89 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_48609903 0.87 ENST00000268933.3
EPN3
epsin 3
chr5_-_43412418 0.86 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr10_-_61900762 0.83 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_79765071 0.81 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr9_+_74729511 0.81 ENST00000545168.1
GDA
guanine deaminase
chr20_-_56285595 0.81 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr21_+_35736302 0.80 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr16_-_69760409 0.79 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr14_-_74551172 0.79 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_152779104 0.79 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr17_-_29624343 0.77 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_-_69249863 0.77 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr17_+_48610042 0.76 ENST00000503246.1
EPN3
epsin 3
chr15_+_47476275 0.74 ENST00000558014.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr3_+_156799587 0.74 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr12_-_22063787 0.73 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr12_-_371994 0.72 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr7_-_112635675 0.69 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr1_+_156338993 0.69 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr4_-_170924888 0.68 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr15_-_33360085 0.68 ENST00000334528.9
FMN1
formin 1
chr1_-_153066998 0.68 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr2_+_64069240 0.68 ENST00000497883.1
UGP2
UDP-glucose pyrophosphorylase 2
chr3_+_98482175 0.67 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr1_-_61719160 0.66 ENST00000442027.1
ENST00000596354.1
ENST00000596404.1
RP5-833A20.1
RP5-833A20.1
chr12_-_50290839 0.63 ENST00000552863.1
FAIM2
Fas apoptotic inhibitory molecule 2
chr12_-_75603482 0.63 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr7_+_107301065 0.63 ENST00000265715.3
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr4_+_70916119 0.63 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr11_+_60995849 0.62 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr14_+_101293687 0.62 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr10_+_18629628 0.61 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_+_158991025 0.61 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr1_+_173793641 0.60 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr13_+_24883703 0.60 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr2_+_64069016 0.60 ENST00000488245.2
UGP2
UDP-glucose pyrophosphorylase 2
chr2_-_36779411 0.58 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr15_+_63682335 0.57 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr1_-_156399184 0.57 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chrX_+_85403445 0.57 ENST00000373131.1
DACH2
dachshund homolog 2 (Drosophila)
chr11_-_30105890 0.56 ENST00000527819.1
RP11-624D11.2
RP11-624D11.2
chr13_+_111766897 0.56 ENST00000317133.5
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr17_+_37824411 0.56 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr11_-_117688216 0.55 ENST00000525836.1
DSCAML1
Down syndrome cell adhesion molecule like 1
chr5_+_150051149 0.55 ENST00000523553.1
MYOZ3
myozenin 3
chr17_+_37824217 0.55 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr3_-_81811312 0.54 ENST00000429644.2
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr19_-_45457264 0.54 ENST00000591646.1
CTB-129P6.11
Uncharacterized protein
chr15_+_31196080 0.54 ENST00000561607.1
ENST00000565466.1
FAN1
FANCD2/FANCI-associated nuclease 1
chr11_+_8040739 0.53 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr18_-_60505948 0.53 ENST00000593319.1
AC015989.2
AC015989.2
chr13_+_111893533 0.52 ENST00000478679.1
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_+_73420942 0.52 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
RP11-140I24.1
chr4_+_76481258 0.52 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chrX_+_85403487 0.51 ENST00000373125.4
DACH2
dachshund homolog 2 (Drosophila)
chr15_-_33360342 0.51 ENST00000558197.1
FMN1
formin 1
chr14_+_74551650 0.51 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr12_+_120031264 0.49 ENST00000426426.1
TMEM233
transmembrane protein 233
chr3_+_26735991 0.49 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr2_+_102456277 0.48 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr5_-_176889381 0.48 ENST00000393563.4
ENST00000512501.1
DBN1
drebrin 1
chr2_+_64068844 0.48 ENST00000337130.5
UGP2
UDP-glucose pyrophosphorylase 2
chr3_-_160116995 0.47 ENST00000465537.1
ENST00000486856.1
ENST00000468218.1
ENST00000478370.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_9482010 0.46 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr2_+_64069459 0.46 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr16_-_66864806 0.46 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr18_-_3845321 0.46 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr18_+_29769978 0.46 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr5_+_179125368 0.46 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chr3_+_39509070 0.46 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr2_-_187367356 0.45 ENST00000595956.1
AC018867.2
AC018867.2
chr5_+_78407602 0.45 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chr4_+_95972822 0.45 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_+_173793777 0.45 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr3_-_48632593 0.44 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr17_+_2699697 0.43 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr19_+_54609230 0.43 ENST00000420296.1
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr12_+_110011571 0.43 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr5_+_125758865 0.43 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr20_-_30458354 0.42 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr18_-_3845293 0.42 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr11_-_62323702 0.41 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr19_+_13080296 0.41 ENST00000317060.2
DAND5
DAN domain family member 5, BMP antagonist
chr12_+_70219052 0.41 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr5_+_125758813 0.41 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr8_-_97247759 0.40 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr3_+_124223586 0.40 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chrX_-_138287168 0.40 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr1_+_218683438 0.40 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr17_+_66521936 0.39 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr16_+_32264040 0.39 ENST00000398664.3
TP53TG3D
TP53 target 3D
chr1_-_32169920 0.39 ENST00000373672.3
ENST00000373668.3
COL16A1
collagen, type XVI, alpha 1
chr3_+_35685113 0.39 ENST00000419330.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_+_87857538 0.39 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr16_+_83986827 0.39 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr9_-_14180778 0.38 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr12_+_113229452 0.38 ENST00000389385.4
RPH3A
rabphilin 3A homolog (mouse)
chr7_-_6066183 0.38 ENST00000422786.1
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr19_+_52074502 0.38 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr4_-_4228616 0.38 ENST00000296358.4
OTOP1
otopetrin 1
chr17_+_68100989 0.37 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_+_113229337 0.37 ENST00000552667.1
RPH3A
rabphilin 3A homolog (mouse)
chr8_+_77593448 0.37 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr16_+_30034655 0.36 ENST00000300575.2
C16orf92
chromosome 16 open reading frame 92
chr10_-_4720301 0.36 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr1_-_157069590 0.36 ENST00000454449.2
ETV3L
ets variant 3-like
chr10_+_68685764 0.36 ENST00000361320.4
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr22_+_18632666 0.35 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr1_-_154832316 0.34 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_+_59250815 0.34 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr15_-_43877062 0.34 ENST00000381885.1
ENST00000396923.3
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr1_+_202431859 0.33 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr3_+_98482159 0.33 ENST00000468553.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr12_+_113229543 0.33 ENST00000447659.2
RPH3A
rabphilin 3A homolog (mouse)
chr17_+_68101117 0.33 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_33914424 0.33 ENST00000590432.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr17_+_33914460 0.33 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_+_141463897 0.33 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr1_-_110155671 0.32 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr2_-_74517829 0.32 ENST00000432728.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr5_+_140723601 0.32 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chrX_-_31285042 0.31 ENST00000378680.2
ENST00000378723.3
DMD
dystrophin
chr16_-_3068171 0.31 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr1_-_32169761 0.31 ENST00000271069.6
COL16A1
collagen, type XVI, alpha 1
chr14_-_60337684 0.31 ENST00000267484.5
RTN1
reticulon 1
chr15_-_43876702 0.31 ENST00000348806.6
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr6_-_135271219 0.30 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr14_-_47812321 0.30 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr17_-_14683517 0.30 ENST00000379640.1
AC005863.1
AC005863.1
chr2_+_27760247 0.30 ENST00000447166.1
AC109829.1
Uncharacterized protein
chrX_-_51797351 0.30 ENST00000375644.3
RP11-114H20.1
RP11-114H20.1
chr11_-_61687739 0.30 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr2_-_38466726 0.30 ENST00000450854.1
AC009229.5
AC009229.5
chr2_+_20650796 0.30 ENST00000448241.1
AC023137.2
AC023137.2
chr10_-_91403625 0.30 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr14_-_36536396 0.30 ENST00000546376.1
RP11-116N8.4
RP11-116N8.4
chr1_-_153113927 0.30 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr10_+_115939008 0.29 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
TDRD1
tudor domain containing 1
chr12_+_60083118 0.29 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_10334585 0.29 ENST00000430179.1
ENST00000449238.2
ENST00000437422.2
ENST00000287656.7
ENST00000457360.1
ENST00000439975.2
ENST00000446937.2
GHRL
ghrelin/obestatin prepropeptide
chr15_-_79576156 0.29 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr2_-_55496476 0.29 ENST00000441307.1
MTIF2
mitochondrial translational initiation factor 2
chr2_-_27545921 0.29 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr22_-_50523807 0.28 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_+_44427230 0.28 ENST00000444029.1
PARVB
parvin, beta
chrX_+_51942963 0.28 ENST00000375625.3
RP11-363G10.2
RP11-363G10.2
chr5_+_149877334 0.28 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_+_67498295 0.28 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_-_64187973 0.28 ENST00000583358.1
ENST00000392769.2
CEP112
centrosomal protein 112kDa
chr11_+_64685026 0.28 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chrX_-_31284974 0.27 ENST00000378702.4
DMD
dystrophin
chr7_+_5938351 0.27 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr3_+_154801678 0.27 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr1_-_60392452 0.27 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr6_+_52930237 0.27 ENST00000323557.7
FBXO9
F-box protein 9
chr21_+_38888740 0.27 ENST00000597817.1
AP001421.1
Uncharacterized protein
chrX_-_24665353 0.26 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_+_115822233 0.26 ENST00000393146.2
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr19_-_5719860 0.26 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr14_-_68066849 0.26 ENST00000558493.1
ENST00000561272.1
PIGH
phosphatidylinositol glycan anchor biosynthesis, class H
chr1_+_10459433 0.26 ENST00000465632.1
ENST00000460189.1
PGD
phosphogluconate dehydrogenase
chr13_+_115000556 0.25 ENST00000252458.6
CDC16
cell division cycle 16
chr21_-_27107198 0.25 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr11_+_101983176 0.25 ENST00000524575.1
YAP1
Yes-associated protein 1
chr14_+_61449197 0.25 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr3_+_119013185 0.25 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr15_+_99645277 0.25 ENST00000336292.6
ENST00000328642.7
SYNM
synemin, intermediate filament protein
chr7_-_2883928 0.25 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr14_+_105927191 0.25 ENST00000550551.1
MTA1
metastasis associated 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.4 1.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.4 2.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.3 2.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 1.6 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 0.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 2.5 GO:0070995 NADPH oxidation(GO:0070995)
0.3 1.1 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.3 0.8 GO:0006147 guanine catabolic process(GO:0006147)
0.3 1.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 2.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 0.8 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.2 0.5 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 1.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.7 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
0.1 1.2 GO:0030242 pexophagy(GO:0030242)
0.1 1.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1 0.3 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.5 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 4.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 1.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.8 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.5 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0042000 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.4 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.6 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 1.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 2.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 1.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 1.0 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 2.2 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.7 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.6 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 2.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.1 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0030118 clathrin coat(GO:0030118)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:1990175 EH domain binding(GO:1990175)
0.5 1.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.4 1.1 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.4 2.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.3 2.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.3 2.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 0.8 GO:0008892 guanine deaminase activity(GO:0008892)
0.3 0.8 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.2 3.1 GO:0031433 telethonin binding(GO:0031433)
0.2 1.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 1.0 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.2 0.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.5 GO:0070336 flap-structured DNA binding(GO:0070336)
0.2 1.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 0.5 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.4 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 3.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 4.6 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 0.2 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 2.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.9 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP