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Illumina Body Map 2, young vs old

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Results for NKX3-2

Z-value: 0.12

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Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
NKX3-2
ENSG00000109705.7 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg19_v2_chr4_-_13546632_13546674-0.028.9e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_99573677 3.97 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr15_+_89402148 3.82 ENST00000560601.1
ACAN
aggrecan
chr11_-_102401469 3.77 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr17_+_68071389 3.40 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_26593649 3.31 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr7_-_120498357 3.17 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr5_+_78407602 3.13 ENST00000274353.5
ENST00000524080.1
BHMT
betaine--homocysteine S-methyltransferase
chrX_+_105937068 2.99 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr3_+_125694347 2.98 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chrX_+_105936982 2.66 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr11_-_128737163 2.54 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr12_-_54978086 2.53 ENST00000553113.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr11_-_128737259 2.52 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr12_+_56075330 2.40 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr11_-_119993979 2.31 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr8_+_35649365 2.31 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr6_-_47010061 2.24 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr5_+_169780485 2.22 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr11_-_26593779 2.18 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr7_-_50628745 2.16 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr11_+_34642656 2.15 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr2_+_79347577 2.14 ENST00000233735.1
REG1A
regenerating islet-derived 1 alpha
chr10_+_5005445 2.03 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr11_-_26593677 2.01 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr7_-_99573640 2.01 ENST00000411734.1
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr2_-_220435963 1.93 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr17_+_68071458 1.90 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_-_49965663 1.83 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4
A kinase (PRKA) anchor protein 4
chr5_+_169931009 1.80 ENST00000328939.4
ENST00000390656.4
KCNIP1
Kv channel interacting protein 1
chr5_+_68711209 1.80 ENST00000512803.1
MARVELD2
MARVEL domain containing 2
chr12_-_53298841 1.78 ENST00000293308.6
KRT8
keratin 8
chr10_-_98031310 1.67 ENST00000427367.2
ENST00000413476.2
BLNK
B-cell linker
chr6_-_160679905 1.58 ENST00000366953.3
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr16_-_20566616 1.58 ENST00000569163.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr14_-_67859422 1.58 ENST00000556532.1
PLEK2
pleckstrin 2
chr1_-_204183071 1.56 ENST00000308302.3
GOLT1A
golgi transport 1A
chr4_-_168155700 1.56 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chrX_-_107681633 1.54 ENST00000394872.2
ENST00000334504.7
COL4A6
collagen, type IV, alpha 6
chrX_+_38420623 1.54 ENST00000378482.2
TSPAN7
tetraspanin 7
chr9_-_34397800 1.49 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr9_+_35906176 1.49 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr2_+_17721920 1.49 ENST00000295156.4
VSNL1
visinin-like 1
chr3_-_116163830 1.48 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr10_-_98031265 1.47 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr12_-_122296755 1.46 ENST00000289004.4
HPD
4-hydroxyphenylpyruvate dioxygenase
chr16_-_21289627 1.46 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr10_-_95360983 1.45 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr9_+_34458771 1.45 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr7_-_107642348 1.44 ENST00000393561.1
LAMB1
laminin, beta 1
chr5_+_40909354 1.44 ENST00000313164.9
C7
complement component 7
chr2_+_155555201 1.44 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr2_-_220436248 1.43 ENST00000265318.4
OBSL1
obscurin-like 1
chr4_-_168155730 1.43 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_-_51412584 1.42 ENST00000431178.2
KLK4
kallikrein-related peptidase 4
chrX_-_107681555 1.39 ENST00000545689.1
ENST00000538570.1
COL4A6
collagen, type IV, alpha 6
chr5_-_35048047 1.37 ENST00000231420.6
AGXT2
alanine--glyoxylate aminotransferase 2
chr17_-_55911970 1.34 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
RP11-60A24.3
chr3_-_149688502 1.34 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chrX_+_38420783 1.34 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr5_+_169931249 1.33 ENST00000520740.1
KCNIP1
Kv channel interacting protein 1
chr8_+_87111059 1.32 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr1_+_176432298 1.32 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr1_-_217262933 1.32 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr4_-_168155577 1.29 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_-_36297348 1.29 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr1_-_160040038 1.27 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr12_-_21927736 1.27 ENST00000240662.2
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr4_-_168155417 1.27 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr11_-_8739383 1.26 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chrX_+_18725758 1.26 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr15_-_56035177 1.25 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr1_-_217262969 1.24 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr1_-_24438664 1.21 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3
myomesin 3
chr1_-_95783809 1.21 ENST00000423410.1
RP4-586O15.1
RP4-586O15.1
chr8_+_144295067 1.20 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr11_-_8739566 1.19 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr6_+_43112037 1.19 ENST00000473339.1
PTK7
protein tyrosine kinase 7
chr15_+_69857515 1.19 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chrX_-_15683147 1.17 ENST00000380342.3
TMEM27
transmembrane protein 27
chr1_-_216978709 1.17 ENST00000360012.3
ESRRG
estrogen-related receptor gamma
chr4_-_175041663 1.17 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr20_-_39995467 1.16 ENST00000332312.3
EMILIN3
elastin microfibril interfacer 3
chr1_-_21059029 1.15 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr1_-_217250231 1.15 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr19_+_48867652 1.13 ENST00000344846.2
SYNGR4
synaptogyrin 4
chr6_+_24357131 1.13 ENST00000274766.1
KAAG1
kidney associated antigen 1
chr8_+_86376081 1.12 ENST00000285379.5
CA2
carbonic anhydrase II
chr1_-_24469602 1.10 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr11_-_1036706 1.09 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr3_+_50192537 1.09 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_-_100551141 1.08 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr15_-_80695917 1.06 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr18_+_28898052 1.06 ENST00000257192.4
DSG1
desmoglein 1
chr3_-_42917363 1.06 ENST00000437102.1
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr15_+_97326619 1.05 ENST00000328504.3
SPATA8
spermatogenesis associated 8
chr12_+_56473939 1.05 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr9_+_35161998 1.05 ENST00000396787.1
ENST00000378495.3
ENST00000378496.4
UNC13B
unc-13 homolog B (C. elegans)
chr6_-_136788001 1.04 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr1_+_10509971 1.04 ENST00000320498.4
CORT
cortistatin
chr3_+_50192499 1.02 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr12_+_6309517 1.02 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr7_-_8276508 1.01 ENST00000401396.1
ENST00000317367.5
ICA1
islet cell autoantigen 1, 69kDa
chr9_+_34458851 1.01 ENST00000545019.1
DNAI1
dynein, axonemal, intermediate chain 1
chr1_+_210111534 0.99 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
SYT14
synaptotagmin XIV
chr10_+_7745232 0.99 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_-_117512264 0.99 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr3_-_139199565 0.99 ENST00000511956.1
RBP2
retinol binding protein 2, cellular
chr2_-_42160486 0.98 ENST00000427054.1
AC104654.2
AC104654.2
chr4_+_148402069 0.98 ENST00000358556.4
ENST00000339690.5
ENST00000511804.1
ENST00000324300.5
EDNRA
endothelin receptor type A
chr18_+_55816546 0.97 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr2_-_160919112 0.96 ENST00000283243.7
ENST00000392771.1
PLA2R1
phospholipase A2 receptor 1, 180kDa
chr3_+_50192457 0.96 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_+_60280458 0.95 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chr10_+_7745303 0.95 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_6845578 0.94 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr11_-_111175739 0.93 ENST00000532918.1
COLCA1
colorectal cancer associated 1
chrX_-_71526813 0.92 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr7_-_79082867 0.90 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_74408739 0.90 ENST00000529912.1
CHRDL2
chordin-like 2
chr13_+_37247934 0.89 ENST00000315190.3
SERTM1
serine-rich and transmembrane domain containing 1
chr4_-_141348763 0.89 ENST00000509477.1
CLGN
calmegin
chr6_-_27279949 0.88 ENST00000444565.1
ENST00000377451.2
POM121L2
POM121 transmembrane nucleoporin-like 2
chrX_+_76709648 0.87 ENST00000439435.1
FGF16
fibroblast growth factor 16
chr3_-_160117035 0.87 ENST00000489004.1
ENST00000496589.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr16_+_57406368 0.87 ENST00000006053.6
ENST00000563383.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr16_-_20416053 0.86 ENST00000302451.4
PDILT
protein disulfide isomerase-like, testis expressed
chr17_+_30593195 0.86 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr14_+_21467414 0.84 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr8_-_30706608 0.84 ENST00000256246.2
TEX15
testis expressed 15
chr7_-_1595756 0.83 ENST00000441933.1
TMEM184A
transmembrane protein 184A
chr12_+_70219052 0.83 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr5_+_68710906 0.82 ENST00000325631.5
ENST00000454295.2
MARVELD2
MARVEL domain containing 2
chr12_-_10978957 0.82 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr3_-_160117301 0.81 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr9_+_124329336 0.80 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr10_-_7708918 0.80 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr6_-_11382478 0.80 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr7_-_135412925 0.79 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr4_+_123300591 0.79 ENST00000439307.1
ENST00000388724.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr6_-_138833630 0.79 ENST00000533765.1
NHSL1
NHS-like 1
chr17_-_39928106 0.79 ENST00000540235.1
JUP
junction plakoglobin
chr2_+_186603545 0.79 ENST00000424728.1
FSIP2
fibrous sheath interacting protein 2
chr4_+_113970772 0.78 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr19_+_36545833 0.77 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chr2_-_180610767 0.77 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr3_+_132316081 0.77 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr4_+_159727222 0.77 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr9_+_15553055 0.77 ENST00000380701.3
CCDC171
coiled-coil domain containing 171
chr1_+_205473784 0.76 ENST00000478560.1
ENST00000443813.2
CDK18
cyclin-dependent kinase 18
chr10_+_18629628 0.76 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_+_22852791 0.75 ENST00000413794.2
RP11-114G22.1
RP11-114G22.1
chr4_+_169575875 0.75 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr19_-_38747172 0.74 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr17_+_4854375 0.74 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr3_-_149688896 0.74 ENST00000239940.7
PFN2
profilin 2
chr1_+_6845497 0.73 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr5_+_127039075 0.72 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr1_+_210111570 0.72 ENST00000367019.1
ENST00000472886.1
SYT14
synaptotagmin XIV
chr10_+_47746929 0.71 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr17_-_74137374 0.71 ENST00000322957.6
FOXJ1
forkhead box J1
chr4_-_48018680 0.71 ENST00000513178.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr11_-_119993734 0.71 ENST00000533302.1
TRIM29
tripartite motif containing 29
chr9_-_23821842 0.71 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr11_-_123065989 0.71 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr1_+_20617362 0.70 ENST00000375079.2
ENST00000289815.8
ENST00000375083.4
ENST00000289825.4
VWA5B1
von Willebrand factor A domain containing 5B1
chr9_+_6328360 0.70 ENST00000381428.1
ENST00000314556.3
TPD52L3
tumor protein D52-like 3
chr15_-_37393406 0.70 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr1_+_86889769 0.70 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr2_+_98703595 0.69 ENST00000435344.1
VWA3B
von Willebrand factor A domain containing 3B
chr12_-_80084862 0.69 ENST00000328827.4
PAWR
PRKC, apoptosis, WT1, regulator
chr20_+_42984330 0.69 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr6_-_47009996 0.69 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr12_+_6309963 0.68 ENST00000382515.2
CD9
CD9 molecule
chr17_-_73511584 0.67 ENST00000321617.3
CASKIN2
CASK interacting protein 2
chr9_+_15552867 0.67 ENST00000535968.1
CCDC171
coiled-coil domain containing 171
chr8_-_19093121 0.66 ENST00000518417.1
RP11-1080G15.1
RP11-1080G15.1
chr2_+_98703643 0.66 ENST00000477737.1
VWA3B
von Willebrand factor A domain containing 3B
chr3_-_100558953 0.66 ENST00000533795.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr10_-_47173994 0.66 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr4_-_141348999 0.65 ENST00000325617.5
CLGN
calmegin
chr15_+_97326659 0.65 ENST00000558553.1
SPATA8
spermatogenesis associated 8
chr16_-_86542652 0.65 ENST00000599749.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr2_+_171673417 0.65 ENST00000344257.5
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr8_-_123706338 0.65 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr19_-_6720686 0.65 ENST00000245907.6
C3
complement component 3
chr11_-_107590383 0.64 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr4_-_141348789 0.63 ENST00000414773.1
CLGN
calmegin
chr4_+_159727272 0.63 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr2_-_45165994 0.63 ENST00000444871.2
RP11-89K21.1
RP11-89K21.1
chr1_-_222886526 0.62 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr10_+_35415851 0.62 ENST00000374726.3
CREM
cAMP responsive element modulator
chr8_-_49834299 0.62 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr6_+_24775641 0.62 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr15_+_41136734 0.62 ENST00000568580.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr19_+_41497178 0.61 ENST00000324071.4
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr3_-_49933249 0.61 ENST00000434765.1
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr10_+_101088836 0.61 ENST00000356713.4
CNNM1
cyclin M1
chr6_+_155443048 0.60 ENST00000535583.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_-_30080863 0.59 ENST00000540829.1
TRIM31
tripartite motif containing 31
chrX_-_131262048 0.59 ENST00000298542.4
FRMD7
FERM domain containing 7

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.7 2.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.5 1.4 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.5 1.4 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.4 1.1 GO:0042938 dipeptide transport(GO:0042938)
0.4 1.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.0 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.3 1.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.3 1.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 3.9 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.3 2.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 1.8 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.5 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.2 1.2 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.2 0.7 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 5.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 13.6 GO:0010107 potassium ion import(GO:0010107)
0.2 3.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.6 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.6 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.2 4.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 4.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.6 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 1.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 3.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 1.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.2 0.8 GO:1900747 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.5 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.0 GO:2000302 regulation of synaptic vesicle priming(GO:0010807) presynaptic dense core granule exocytosis(GO:0099525) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.6 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 3.6 GO:0044849 estrous cycle(GO:0044849)
0.1 0.4 GO:0044335 neural crest cell fate commitment(GO:0014034) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.1 6.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.9 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.9 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.6 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.9 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 1.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.7 GO:0044026 DNA hypermethylation(GO:0044026)
0.1 1.6 GO:1901374 acetate ester transport(GO:1901374)
0.1 0.4 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
0.1 1.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 2.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 7.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.5 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 3.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 8.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.9 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 1.2 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.1 1.3 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.4 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.6 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.3 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 5.3 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 2.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.4 GO:0097186 amelogenesis(GO:0097186)
0.0 2.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.6 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 3.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.6 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 2.2 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.9 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:1903061 positive regulation of protein lipidation(GO:1903061) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 1.0 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.8 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0007099 centriole replication(GO:0007099)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 1.9 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0031529 ruffle organization(GO:0031529)
0.0 2.1 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043257 laminin-8 complex(GO:0043257)
0.4 3.4 GO:1990393 3M complex(GO:1990393)
0.3 1.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.3 2.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 0.8 GO:1990032 parallel fiber(GO:1990032)
0.2 1.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.6 GO:0061689 tricellular tight junction(GO:0061689)
0.2 0.8 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.2 2.5 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 0.6 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 1.0 GO:0044305 calyx of Held(GO:0044305)
0.1 17.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 12.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0030055 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 11.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 2.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.0 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.8 GO:0031514 motile cilium(GO:0031514)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 1.6 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.9 8.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.6 4.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 2.1 GO:0047718 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.4 1.6 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.4 1.5 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 1.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.3 7.1 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.3 6.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.8 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 1.4 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.2 0.6 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 5.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 5.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.1 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 3.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.6 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 2.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.8 GO:0019841 retinol binding(GO:0019841)
0.1 2.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 2.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.3 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 2.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 3.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 2.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.7 GO:0005243 gap junction channel activity(GO:0005243)
0.0 5.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.7 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 1.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.0 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.5 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.5 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.8 GO:0019956 chemokine binding(GO:0019956)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 3.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.0 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 9.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 6.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 6.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 5.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.7 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 8.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 4.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 5.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 2.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 3.2 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins