Project

Illumina Body Map 2, young vs old

Navigation
Downloads

Results for NKX6-2

Z-value: 0.08

Motif logo

logo of

Transcription factors associated with NKX6-2

Gene Symbol Gene ID Gene Info
NKX6-2
ENSG00000148826.6 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-2hg19_v2_chr10_-_134599556_1345996530.575.9e-04Click!

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39509070 2.61 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr12_+_41136144 2.60 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr4_+_41258786 2.58 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_110993795 2.56 ENST00000271331.3
PROK1
prokineticin 1
chr17_-_42992856 2.18 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
GFAP
glial fibrillary acidic protein
chr3_-_79816965 2.15 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_-_60097524 2.15 ENST00000342503.4
RTN1
reticulon 1
chr3_+_39509163 2.15 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr1_+_170632250 1.96 ENST00000367760.3
PRRX1
paired related homeobox 1
chr9_+_109685630 1.91 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr6_+_12290586 1.90 ENST00000379375.5
EDN1
endothelin 1
chr2_+_108994633 1.89 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chrX_-_103087136 1.88 ENST00000243298.2
RAB9B
RAB9B, member RAS oncogene family
chr5_+_161275320 1.86 ENST00000437025.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_26505179 1.85 ENST00000376261.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr2_+_200472779 1.83 ENST00000427045.1
ENST00000419243.1
AC093590.1
AC093590.1
chr2_-_217560248 1.82 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr2_-_175711978 1.78 ENST00000409089.2
CHN1
chimerin 1
chr18_+_32290218 1.77 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr2_-_73520667 1.75 ENST00000545030.1
ENST00000436467.2
EGR4
early growth response 4
chr2_-_217559517 1.73 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr2_+_210444142 1.73 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr11_-_126810521 1.69 ENST00000530572.1
RP11-688I9.4
RP11-688I9.4
chr14_-_27066636 1.67 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr4_-_185139062 1.64 ENST00000296741.2
ENPP6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr2_+_210444298 1.57 ENST00000445941.1
MAP2
microtubule-associated protein 2
chrX_+_36254051 1.56 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr14_+_101295638 1.55 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr2_-_175712479 1.52 ENST00000443238.1
CHN1
chimerin 1
chr2_+_210443993 1.52 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr2_-_175712270 1.51 ENST00000295497.7
ENST00000444394.1
CHN1
chimerin 1
chr4_-_87374283 1.47 ENST00000361569.2
MAPK10
mitogen-activated protein kinase 10
chr14_+_72399833 1.45 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr9_+_82186872 1.41 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_-_60097297 1.39 ENST00000395090.1
RTN1
reticulon 1
chr1_-_114696472 1.37 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
SYT6
synaptotagmin VI
chr2_-_211342292 1.35 ENST00000448951.1
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr4_-_87374330 1.34 ENST00000511328.1
ENST00000503911.1
MAPK10
mitogen-activated protein kinase 10
chr12_-_74686314 1.33 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr5_+_161495038 1.25 ENST00000393933.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr12_-_6233828 1.25 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr9_-_23825956 1.22 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr3_+_178276488 1.21 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr3_-_138048682 1.21 ENST00000383180.2
NME9
NME/NM23 family member 9
chr3_-_98241358 1.20 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr9_+_130026756 1.19 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr1_+_85527987 1.19 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr7_-_107880508 1.18 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr8_+_104831472 1.17 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr10_-_71169031 1.15 ENST00000373307.1
TACR2
tachykinin receptor 2
chr3_-_147124547 1.14 ENST00000491672.1
ENST00000383075.3
ZIC4
Zic family member 4
chr8_+_24298531 1.14 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr12_-_28124903 1.14 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone
chrX_+_102840408 1.12 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4
transcription elongation factor A (SII)-like 4
chr1_-_49242553 1.10 ENST00000371833.3
BEND5
BEN domain containing 5
chr5_-_58295712 1.10 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_+_24298597 1.06 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr1_-_190446759 1.06 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr8_+_24298438 1.06 ENST00000441335.2
ADAM7
ADAM metallopeptidase domain 7
chr6_-_26043885 1.05 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr5_-_88120083 1.04 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr1_+_244515930 1.01 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr1_-_243326612 1.00 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr5_+_155753745 1.00 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr5_-_88120151 1.00 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chrX_-_138287168 1.00 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr17_-_57604227 0.98 ENST00000584262.1
RP11-567L7.6
RP11-567L7.6
chr16_+_25228242 0.98 ENST00000219660.5
AQP8
aquaporin 8
chr3_+_156799587 0.97 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr4_-_140201333 0.96 ENST00000398955.1
MGARP
mitochondria-localized glutamic acid-rich protein
chr2_-_80531399 0.96 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chrX_-_80457385 0.95 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr9_-_23826298 0.94 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr5_+_161274685 0.93 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr18_+_32402321 0.93 ENST00000587723.1
DTNA
dystrobrevin, alpha
chr3_+_16216210 0.92 ENST00000437509.1
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr5_+_161274940 0.92 ENST00000393943.4
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr21_-_36421626 0.92 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr5_+_166711804 0.91 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr14_-_27066960 0.90 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chrX_+_35937843 0.90 ENST00000297866.5
CXorf22
chromosome X open reading frame 22
chr2_+_233527443 0.90 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chrX_+_135230712 0.88 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr15_+_49715449 0.86 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr22_+_17956618 0.86 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr1_-_109935819 0.86 ENST00000538502.1
SORT1
sortilin 1
chr5_-_20575959 0.83 ENST00000507958.1
CDH18
cadherin 18, type 2
chr21_-_36421535 0.83 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr15_-_96036999 0.83 ENST00000554412.2
RP11-398J10.2
RP11-398J10.2
chr10_+_50887683 0.82 ENST00000374113.3
ENST00000374111.3
ENST00000374112.3
ENST00000535836.1
C10orf53
chromosome 10 open reading frame 53
chr15_+_49715293 0.82 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr19_-_49220084 0.80 ENST00000595591.1
ENST00000356751.4
ENST00000594582.1
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_-_80531720 0.80 ENST00000416268.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr15_+_74421961 0.79 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_115397424 0.78 ENST00000369522.3
ENST00000455987.1
SYCP1
synaptonemal complex protein 1
chr7_+_123241908 0.76 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr6_+_26199737 0.76 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr19_+_12175535 0.74 ENST00000550826.1
ZNF844
zinc finger protein 844
chr18_+_28923589 0.72 ENST00000462981.2
DSG1
desmoglein 1
chr16_+_70695570 0.71 ENST00000597002.1
FLJ00418
FLJ00418
chr14_+_52164820 0.70 ENST00000554167.1
FRMD6
FERM domain containing 6
chr6_-_80247140 0.70 ENST00000392959.1
ENST00000467898.3
LCA5
Leber congenital amaurosis 5
chr18_-_12656715 0.69 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr6_-_131277510 0.69 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_16216137 0.69 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chrX_+_10124977 0.69 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr3_+_159557637 0.68 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr2_+_108994466 0.68 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr6_-_56716686 0.67 ENST00000520645.1
DST
dystonin
chr9_-_16215897 0.66 ENST00000433347.1
C9orf92
chromosome 9 open reading frame 92
chr9_-_93405352 0.66 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr20_+_57467204 0.65 ENST00000603546.1
GNAS
GNAS complex locus
chr1_-_247887345 0.65 ENST00000366485.1
OR14A2
olfactory receptor, family 14, subfamily A, member 2
chr12_+_111284764 0.63 ENST00000545036.1
ENST00000308208.5
CCDC63
coiled-coil domain containing 63
chr7_-_78400364 0.62 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_135388147 0.61 ENST00000394141.1
GPR112
G protein-coupled receptor 112
chr10_+_123951957 0.61 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr6_-_80247105 0.59 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr8_+_79428539 0.59 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_+_32873190 0.59 ENST00000375025.4
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr15_-_89764929 0.58 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr3_-_193272874 0.57 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr15_-_42302445 0.57 ENST00000413860.2
PLA2G4E
phospholipase A2, group IVE
chr8_-_82395461 0.57 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr9_-_21385396 0.57 ENST00000380206.2
IFNA2
interferon, alpha 2
chr12_+_25205568 0.56 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr19_+_12175596 0.56 ENST00000441304.2
ZNF844
zinc finger protein 844
chr18_-_52989217 0.55 ENST00000570287.2
TCF4
transcription factor 4
chr4_+_26324474 0.54 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr8_+_104831554 0.54 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_101295407 0.54 ENST00000596284.1
AL117190.2
AL117190.2
chr3_+_140981456 0.52 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr6_+_97753454 0.52 ENST00000574739.1
RP3-418C23.2
RP3-418C23.2
chr4_+_190580748 0.52 ENST00000513681.1
RP11-462G22.1
RP11-462G22.1
chr1_+_151253991 0.51 ENST00000443959.1
ZNF687
zinc finger protein 687
chr1_-_21377447 0.51 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_45837959 0.51 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chrX_+_55744166 0.51 ENST00000374941.4
ENST00000414239.1
RRAGB
Ras-related GTP binding B
chr1_-_110933663 0.50 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr6_+_158733692 0.50 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr12_+_7022909 0.49 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr1_-_110933611 0.49 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr5_+_95066823 0.49 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr6_+_47666275 0.49 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr1_+_201617264 0.49 ENST00000367296.4
NAV1
neuron navigator 1
chr8_-_42358742 0.48 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr7_-_22233442 0.48 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_169757750 0.48 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr22_-_40929812 0.48 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_-_25479811 0.48 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr1_-_186430222 0.47 ENST00000391997.2
PDC
phosducin
chr3_-_45838011 0.47 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr13_-_45048386 0.46 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr1_+_201617450 0.46 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr18_-_19994830 0.46 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr1_+_32379174 0.46 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr12_-_109458820 0.45 ENST00000550490.1
SVOP
SV2 related protein homolog (rat)
chrX_+_55744228 0.45 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chrX_+_134887233 0.45 ENST00000443882.1
CT45A3
cancer/testis antigen family 45, member A3
chr14_+_52164675 0.45 ENST00000555936.1
FRMD6
FERM domain containing 6
chr18_-_52989525 0.44 ENST00000457482.3
TCF4
transcription factor 4
chr1_+_109265033 0.43 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr14_+_88852059 0.43 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr17_-_67057047 0.43 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr7_-_137028534 0.42 ENST00000348225.2
PTN
pleiotrophin
chr3_+_68053359 0.42 ENST00000478136.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr2_+_179318295 0.42 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr6_-_33864684 0.41 ENST00000506222.2
ENST00000533304.1
LINC01016
long intergenic non-protein coding RNA 1016
chr8_-_72268721 0.41 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr1_+_152178320 0.40 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr5_-_88119580 0.40 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr6_-_37665751 0.40 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr16_-_67517716 0.40 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr1_+_174933899 0.40 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr2_-_105882585 0.39 ENST00000595531.1
AC012360.2
LOC644617 protein; Uncharacterized protein
chr7_-_137028498 0.39 ENST00000393083.2
PTN
pleiotrophin
chr17_-_67057114 0.38 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr12_+_111284805 0.38 ENST00000552694.1
CCDC63
coiled-coil domain containing 63
chr10_-_100995540 0.38 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr18_-_30716038 0.37 ENST00000581852.1
CCDC178
coiled-coil domain containing 178
chr8_+_26150628 0.37 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_+_48510269 0.36 ENST00000446524.1
OR4A47
olfactory receptor, family 4, subfamily A, member 47
chr5_-_146258205 0.36 ENST00000394413.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr5_-_16916624 0.35 ENST00000513882.1
MYO10
myosin X
chr9_+_88556036 0.35 ENST00000361671.5
ENST00000416045.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr7_-_84122033 0.35 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_+_104831440 0.35 ENST00000515551.1
RIMS2
regulating synaptic membrane exocytosis 2
chr7_-_112635675 0.35 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr21_-_36421401 0.34 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr10_+_91589309 0.34 ENST00000448490.1
LINC00865
long intergenic non-protein coding RNA 865
chr2_+_179149636 0.34 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr11_-_9088284 0.34 ENST00000531429.1
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr17_-_67057203 0.34 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr12_-_53045948 0.34 ENST00000309680.3
KRT2
keratin 2
chr12_+_54422142 0.33 ENST00000243108.4
HOXC6
homeobox C6
chr7_-_78400598 0.33 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_15095832 0.33 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr16_+_14802801 0.32 ENST00000526520.1
ENST00000531598.2
NPIPA3
nuclear pore complex interacting protein family, member A3
chr14_-_75530693 0.32 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr4_-_108204846 0.32 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.9 2.6 GO:0007412 axon target recognition(GO:0007412)
0.6 1.7 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.5 1.9 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 2.2 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.3 2.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 4.8 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 1.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 0.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.3 1.9 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.2 1.1 GO:0035106 negative regulation of luteinizing hormone secretion(GO:0033685) operant conditioning(GO:0035106)
0.2 5.0 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.8 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 1.0 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 2.0 GO:0048664 neuron fate determination(GO:0048664)
0.2 2.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.1 1.0 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.1 GO:0003383 apical constriction(GO:0003383)
0.1 2.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 1.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 5.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.5 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 2.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.7 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 1.8 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.1 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 1.0 GO:0015824 proline transport(GO:0015824)
0.1 0.5 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 2.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 6.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.7 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 1.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 2.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.4 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 1.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.7 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.0 GO:0006833 water transport(GO:0006833)
0.0 0.3 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 2.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0051836 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.5 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.8 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 1.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 4.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 3.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 5.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.9 GO:0060077 inhibitory synapse(GO:0060077) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 0.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0044297 cell body(GO:0044297)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 2.1 GO:0043194 axon initial segment(GO:0043194)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 3.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.7 GO:0008091 spectrin(GO:0008091)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 4.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 4.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.7 GO:0030426 growth cone(GO:0030426)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 3.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 3.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 4.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 2.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 2.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.9 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 0.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0030305 heparanase activity(GO:0030305)
0.1 4.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 4.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.3 GO:0032093 SAM domain binding(GO:0032093)
0.1 1.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0043295 glutathione binding(GO:0043295)
0.1 1.0 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 1.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 3.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.5 GO:0008083 growth factor activity(GO:0008083)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 2.6 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0070491 repressing transcription factor binding(GO:0070491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 4.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 4.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 2.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.7 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 5.8 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.3 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions