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Illumina Body Map 2, young vs old

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Results for NR0B1

Z-value: 0.04

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Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
NR0B1
ENSG00000169297.6 nuclear receptor subfamily 0 group B member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR0B1hg19_v2_chrX_-_30326445_303266050.144.3e-01Click!

Activity profile of NR0B1 motif

Sorted Z-values of NR0B1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_4845379 3.52 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr2_+_105471969 3.09 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr2_+_220492373 2.71 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr3_-_123168551 2.65 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr6_-_94129244 2.15 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr2_+_220492116 2.04 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr15_-_65067773 2.01 ENST00000300069.4
RBPMS2
RNA binding protein with multiple splicing 2
chr11_-_12030746 1.94 ENST00000533813.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr4_+_150999418 1.93 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr20_-_18038521 1.92 ENST00000278780.6
OVOL2
ovo-like zinc finger 2
chrX_-_128788914 1.86 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr2_+_234545092 1.86 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr2_-_219925189 1.79 ENST00000295731.6
IHH
indian hedgehog
chr11_-_12030629 1.77 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr11_-_12030681 1.75 ENST00000529338.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr1_-_147245484 1.70 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr10_+_112404132 1.64 ENST00000369519.3
RBM20
RNA binding motif protein 20
chr9_+_128509624 1.62 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chrX_-_114468605 1.58 ENST00000538422.1
ENST00000317135.8
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr1_-_147245445 1.39 ENST00000430508.1
GJA5
gap junction protein, alpha 5, 40kDa
chr10_+_60936347 1.36 ENST00000373880.4
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr9_+_71320596 1.35 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr9_+_71320557 1.35 ENST00000541509.1
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr10_-_21463116 1.28 ENST00000417816.2
NEBL
nebulette
chr15_-_73661605 1.26 ENST00000261917.3
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr19_-_45909585 1.23 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_-_40098672 1.23 ENST00000535435.1
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr2_+_155555201 1.21 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_+_181429704 1.19 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr12_+_41086297 1.18 ENST00000551295.2
CNTN1
contactin 1
chr2_+_220306745 1.18 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr13_-_38443860 1.16 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4
transient receptor potential cation channel, subfamily C, member 4
chr1_-_196577489 1.11 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2
potassium channel, subfamily T, member 2
chr6_+_17393839 1.08 ENST00000489374.1
ENST00000378990.2
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_-_119993979 1.07 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr6_+_17393888 1.05 ENST00000493172.1
ENST00000465994.1
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr10_+_18689637 1.04 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_234580525 1.04 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr9_-_35691017 1.02 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr10_-_17659234 1.02 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr8_-_28347737 1.01 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chrX_-_153151586 0.98 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1CAM
L1 cell adhesion molecule
chr1_-_23810664 0.98 ENST00000336689.3
ENST00000437606.2
ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr14_+_96968707 0.97 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr8_+_95653302 0.96 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr2_+_14775215 0.95 ENST00000581929.1
AC011897.1
Uncharacterized protein
chr3_+_111578640 0.95 ENST00000393925.3
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr6_+_44238203 0.95 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr3_-_183979251 0.94 ENST00000296238.3
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_126070726 0.93 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr2_+_234545148 0.92 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr2_+_234580499 0.91 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr9_+_129986734 0.91 ENST00000444677.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr7_+_89841024 0.89 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr12_+_58005204 0.89 ENST00000286494.4
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr2_+_14772810 0.88 ENST00000295092.2
ENST00000331243.4
FAM84A
family with sequence similarity 84, member A
chr6_-_112575687 0.88 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr1_+_117452669 0.87 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr19_-_36523709 0.87 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr14_-_89021077 0.85 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr7_+_89841144 0.85 ENST00000394622.2
ENST00000394632.1
ENST00000426158.1
ENST00000394621.2
ENST00000402625.2
STEAP2
STEAP family member 2, metalloreductase
chr11_-_2160180 0.84 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_111578131 0.82 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr7_-_140340576 0.81 ENST00000275884.6
ENST00000475837.1
DENND2A
DENN/MADD domain containing 2A
chr9_+_128509663 0.81 ENST00000373489.5
ENST00000373483.2
PBX3
pre-B-cell leukemia homeobox 3
chr13_-_33859819 0.81 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_112575758 0.80 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr16_+_2014941 0.80 ENST00000531523.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr5_+_38258511 0.79 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr1_-_223537401 0.78 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4
sushi domain containing 4
chr12_+_56473939 0.78 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr14_-_23822061 0.76 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr3_+_111578027 0.76 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_+_56473628 0.75 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr4_+_88928777 0.75 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr19_-_44143939 0.75 ENST00000222374.2
CADM4
cell adhesion molecule 4
chr19_+_49661037 0.75 ENST00000427978.2
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr3_-_169381183 0.72 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr1_-_223536679 0.72 ENST00000608996.1
SUSD4
sushi domain containing 4
chr3_+_111578583 0.72 ENST00000478922.1
ENST00000477695.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_+_8429031 0.71 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4
angiopoietin-like 4
chr6_+_7541808 0.68 ENST00000379802.3
DSP
desmoplakin
chr10_-_17659357 0.68 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_-_122712079 0.67 ENST00000393583.2
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr6_+_7541845 0.67 ENST00000418664.2
DSP
desmoplakin
chr20_+_55204351 0.66 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr12_-_6484715 0.65 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr19_-_36523529 0.64 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr12_+_65672702 0.64 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr5_+_79331164 0.64 ENST00000350881.2
THBS4
thrombospondin 4
chr14_-_23822080 0.63 ENST00000397267.1
ENST00000354772.3
SLC22A17
solute carrier family 22, member 17
chr17_+_77751931 0.62 ENST00000310942.4
ENST00000269399.5
CBX2
chromobox homolog 2
chr15_-_72490114 0.61 ENST00000309731.7
GRAMD2
GRAM domain containing 2
chr10_-_13570533 0.61 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr22_+_51112800 0.61 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr6_-_112575838 0.60 ENST00000455073.1
LAMA4
laminin, alpha 4
chr12_+_49212514 0.59 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr14_+_96968802 0.58 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr4_-_135122903 0.57 ENST00000421491.3
ENST00000529122.2
PABPC4L
poly(A) binding protein, cytoplasmic 4-like
chr2_+_5832799 0.57 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr2_+_201170999 0.56 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr22_+_29279552 0.56 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chrX_+_9754461 0.56 ENST00000380913.3
SHROOM2
shroom family member 2
chr19_-_46272106 0.56 ENST00000560168.1
SIX5
SIX homeobox 5
chr20_+_306221 0.56 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr4_-_168155730 0.56 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr2_+_201171577 0.56 ENST00000409397.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_50355647 0.55 ENST00000293599.6
AQP5
aquaporin 5
chr20_+_306177 0.55 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chrX_-_130423240 0.54 ENST00000370910.1
ENST00000370901.4
IGSF1
immunoglobulin superfamily, member 1
chr2_-_183903133 0.54 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr15_-_82338460 0.54 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr2_+_27301435 0.53 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr1_+_26146674 0.53 ENST00000525713.1
ENST00000374301.3
MTFR1L
mitochondrial fission regulator 1-like
chr6_+_143381979 0.53 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1
androgen-induced 1
chr2_+_66662249 0.53 ENST00000560281.2
MEIS1
Meis homeobox 1
chr7_-_8302298 0.53 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr13_+_98794810 0.53 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_10674528 0.52 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr12_-_39837192 0.51 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr16_+_15528332 0.51 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr1_+_26146397 0.50 ENST00000374303.2
ENST00000533762.1
ENST00000529116.1
ENST00000474295.1
ENST00000488327.2
ENST00000472643.1
ENST00000526894.1
ENST00000524618.1
ENST00000374307.5
MTFR1L
mitochondrial fission regulator 1-like
chrX_-_119445306 0.50 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr4_-_168155417 0.50 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_+_159593418 0.50 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr8_+_95653427 0.49 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr12_+_41086215 0.49 ENST00000547702.1
ENST00000551424.1
CNTN1
contactin 1
chr16_+_89894875 0.49 ENST00000393062.2
SPIRE2
spire-type actin nucleation factor 2
chr19_+_55795493 0.48 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr3_-_64431058 0.48 ENST00000564377.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr16_+_55357672 0.48 ENST00000290552.7
IRX6
iroquois homeobox 6
chrX_+_106163626 0.47 ENST00000336803.1
CLDN2
claudin 2
chr12_+_27677085 0.47 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr2_+_201171064 0.46 ENST00000451764.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chrX_-_119445263 0.46 ENST00000309720.5
TMEM255A
transmembrane protein 255A
chr3_-_52567792 0.46 ENST00000307092.4
ENST00000422318.2
ENST00000459839.1
NT5DC2
5'-nucleotidase domain containing 2
chrX_+_19362011 0.46 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
PDHA1
pyruvate dehydrogenase (lipoamide) alpha 1
chr9_+_129987488 0.45 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr3_-_169381166 0.45 ENST00000486748.1
MECOM
MDS1 and EVI1 complex locus
chr2_-_96812751 0.45 ENST00000449242.1
AC012307.2
AC012307.2
chr19_+_41036371 0.44 ENST00000392023.1
SPTBN4
spectrin, beta, non-erythrocytic 4
chr6_-_53530474 0.44 ENST00000370905.3
KLHL31
kelch-like family member 31
chr17_+_40811283 0.44 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr1_+_155247207 0.43 ENST00000368358.3
HCN3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr19_+_12305824 0.43 ENST00000415793.1
ENST00000440004.1
ENST00000426044.1
CTD-2666L21.1
CTD-2666L21.1
chr3_+_140770183 0.43 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_+_110754094 0.43 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr11_-_117667806 0.42 ENST00000527706.1
ENST00000321322.6
DSCAML1
Down syndrome cell adhesion molecule like 1
chr2_+_204193149 0.42 ENST00000422511.2
ABI2
abl-interactor 2
chr5_-_42811986 0.41 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr2_+_220306238 0.41 ENST00000435853.1
SPEG
SPEG complex locus
chr19_+_49660997 0.41 ENST00000598691.1
ENST00000252826.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr1_-_46598371 0.40 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr7_-_8302164 0.40 ENST00000447326.1
ENST00000406470.2
ICA1
islet cell autoantigen 1, 69kDa
chr4_-_87278857 0.40 ENST00000509464.1
ENST00000511167.1
MAPK10
mitogen-activated protein kinase 10
chr2_+_159313452 0.40 ENST00000389757.3
ENST00000389759.3
PKP4
plakophilin 4
chr17_+_7308172 0.39 ENST00000575301.1
NLGN2
neuroligin 2
chr12_+_56661033 0.39 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr6_-_110500826 0.38 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr19_-_51466681 0.38 ENST00000456750.2
KLK6
kallikrein-related peptidase 6
chrX_-_130423386 0.38 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr12_+_56661461 0.38 ENST00000546544.1
ENST00000553234.1
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr3_+_128720424 0.38 ENST00000480450.1
ENST00000436022.2
EFCC1
EF-hand and coiled-coil domain containing 1
chr11_-_63536113 0.38 ENST00000433688.1
ENST00000546282.2
C11orf95
RP11-466C23.4
chromosome 11 open reading frame 95
RP11-466C23.4
chr12_+_107168342 0.38 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr7_+_103969104 0.37 ENST00000424859.1
ENST00000535008.1
ENST00000401970.2
ENST00000543266.1
LHFPL3
lipoma HMGIC fusion partner-like 3
chr11_-_118023490 0.37 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr13_+_33590553 0.36 ENST00000380099.3
KL
klotho
chr1_+_180601139 0.35 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr12_+_107168418 0.35 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr14_-_27066960 0.35 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr1_-_177133998 0.35 ENST00000367657.3
ASTN1
astrotactin 1
chr20_+_49348109 0.35 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr5_+_121647764 0.35 ENST00000261368.8
ENST00000379533.2
ENST00000379536.2
ENST00000379538.3
SNCAIP
synuclein, alpha interacting protein
chr7_+_149411860 0.34 ENST00000486744.1
KRBA1
KRAB-A domain containing 1
chr17_+_68101117 0.33 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_8301682 0.33 ENST00000396675.3
ENST00000430867.1
ICA1
islet cell autoantigen 1, 69kDa
chr5_+_169780485 0.33 ENST00000377360.4
KCNIP1
Kv channel interacting protein 1
chr16_+_2014993 0.33 ENST00000564014.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr6_-_114664180 0.32 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr1_+_52608046 0.32 ENST00000357206.2
ENST00000287727.3
ZFYVE9
zinc finger, FYVE domain containing 9
chr2_+_204193129 0.32 ENST00000417864.1
ABI2
abl-interactor 2
chr16_-_28937027 0.32 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr1_+_244816237 0.31 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr1_+_44401479 0.31 ENST00000438616.3
ARTN
artemin
chr3_-_33260707 0.30 ENST00000309558.3
SUSD5
sushi domain containing 5
chr4_-_177713788 0.30 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr10_-_79397316 0.30 ENST00000372421.5
ENST00000457953.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr7_-_8302207 0.29 ENST00000407906.1
ICA1
islet cell autoantigen 1, 69kDa
chr15_-_83953466 0.29 ENST00000345382.2
BNC1
basonuclin 1
chr1_-_153958805 0.28 ENST00000368575.3
RAB13
RAB13, member RAS oncogene family
chr12_+_56473910 0.28 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_46598284 0.28 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr13_+_47127293 0.28 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_+_204192942 0.28 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr15_+_74422585 0.27 ENST00000561740.1
ENST00000435464.1
ENST00000453268.2
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_+_166152283 0.27 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_-_559853 0.26 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr8_-_42396721 0.26 ENST00000518384.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr8_-_142011291 0.26 ENST00000521059.1
PTK2
protein tyrosine kinase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR0B1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1990029 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.8 2.4 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.7 5.5 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.7 2.0 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.6 1.9 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.6 3.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 4.7 GO:0051552 flavone metabolic process(GO:0051552)
0.4 1.2 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.4 0.7 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.3 1.9 GO:0060214 endocardium formation(GO:0060214)
0.3 0.9 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.3 1.2 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.3 1.4 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 1.7 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.4 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.2 3.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.6 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 0.5 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.2 2.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 0.6 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 3.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.6 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 1.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 1.0 GO:0098912 membrane depolarization during AV node cell action potential(GO:0086045) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 1.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.6 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.6 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.3 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.4 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:0070631 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.8 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.5 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 4.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.5 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.1 1.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.3 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.0 0.6 GO:0030091 protein repair(GO:0030091)
0.0 1.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.5 GO:0070836 caveola assembly(GO:0070836)
0.0 0.8 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 2.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0051808 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 1.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 1.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 1.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0098855 HCN channel complex(GO:0098855)
0.2 4.0 GO:0045180 basal cortex(GO:0045180)
0.1 3.1 GO:0005922 connexon complex(GO:0005922)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 2.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 2.5 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 2.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 1.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.4 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.0 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.7 2.7 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.5 2.2 GO:0035939 microsatellite binding(GO:0035939)
0.3 0.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.5 GO:0097001 ceramide binding(GO:0097001)
0.3 1.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 4.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 2.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.7 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.2 0.5 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 1.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.5 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 4.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.5 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 1.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 2.0 GO:0005113 patched binding(GO:0005113)
0.1 1.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.9 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.9 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 3.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 4.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 1.8 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.3 GO:0031005 filamin binding(GO:0031005)
0.0 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0050656 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 2.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 1.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 5.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 ST ADRENERGIC Adrenergic Pathway
0.0 1.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling