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Illumina Body Map 2, young vs old

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Results for NR1D1

Z-value: 0.46

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Transcription factors associated with NR1D1

Gene Symbol Gene ID Gene Info
NR1D1
ENSG00000126368.5 nuclear receptor subfamily 1 group D member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1D1hg19_v2_chr17_-_38256973_38256990-0.048.4e-01Click!

Activity profile of NR1D1 motif

Sorted Z-values of NR1D1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51220176 5.07 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr3_-_117716418 4.89 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr14_+_24540731 3.54 ENST00000558859.1
ENST00000559197.1
ENST00000560828.1
ENST00000216775.2
ENST00000560884.1
CPNE6
copine VI (neuronal)
chr14_+_24540046 3.16 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr14_+_24540761 3.01 ENST00000559207.1
CPNE6
copine VI (neuronal)
chr14_+_24540154 2.75 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
CPNE6
copine VI (neuronal)
chr1_-_26233423 2.14 ENST00000357865.2
STMN1
stathmin 1
chr1_-_26232522 2.13 ENST00000399728.1
STMN1
stathmin 1
chr1_-_26232951 2.10 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr14_+_50999744 2.06 ENST00000441560.2
ATL1
atlastin GTPase 1
chr17_-_79139817 2.02 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr9_-_131155773 1.98 ENST00000608502.1
MIR219-2
microRNA 219-2
chr19_-_18995029 1.93 ENST00000596048.1
CERS1
ceramide synthase 1
chr9_+_126773880 1.93 ENST00000373615.4
LHX2
LIM homeobox 2
chr8_+_105235572 1.77 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr6_+_99282570 1.68 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr4_-_21699380 1.67 ENST00000382148.3
KCNIP4
Kv channel interacting protein 4
chr3_+_259218 1.61 ENST00000449294.2
CHL1
cell adhesion molecule L1-like
chr10_+_23216944 1.61 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
ARMC3
armadillo repeat containing 3
chr10_-_43762329 1.57 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr1_+_2398876 1.49 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr7_-_30009542 1.46 ENST00000438497.1
SCRN1
secernin 1
chr17_-_1029866 1.43 ENST00000570525.1
ABR
active BCR-related
chr9_+_103790991 1.42 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr1_-_41131326 1.32 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr10_+_23217006 1.28 ENST00000376528.4
ENST00000447081.1
ARMC3
armadillo repeat containing 3
chr11_-_125365435 1.27 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr11_-_125366018 1.11 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr14_+_23352374 1.09 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr19_+_35810164 1.05 ENST00000598537.1
CD22
CD22 molecule
chr17_-_76128488 1.03 ENST00000322914.3
TMC6
transmembrane channel-like 6
chr17_-_56358287 1.02 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr6_+_31543334 1.01 ENST00000449264.2
TNF
tumor necrosis factor
chr5_-_111312622 0.95 ENST00000395634.3
NREP
neuronal regeneration related protein
chr3_-_52002194 0.91 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr17_-_49825148 0.91 ENST00000575097.1
CA10
carbonic anhydrase X
chr14_-_94595993 0.82 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr5_-_63258261 0.81 ENST00000506598.1
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
chr12_+_57854274 0.78 ENST00000528432.1
GLI1
GLI family zinc finger 1
chrX_+_16964985 0.77 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr7_-_142630820 0.76 ENST00000442623.1
ENST00000265310.1
TRPV5
transient receptor potential cation channel, subfamily V, member 5
chr7_+_64126535 0.73 ENST00000344930.3
ZNF107
zinc finger protein 107
chr1_+_218519577 0.72 ENST00000366930.4
ENST00000366929.4
TGFB2
transforming growth factor, beta 2
chrX_+_54947229 0.72 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO
trophinin
chr6_+_167525277 0.72 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr3_+_58223228 0.72 ENST00000478253.1
ENST00000295962.4
ABHD6
abhydrolase domain containing 6
chr9_+_136243264 0.70 ENST00000371955.1
C9orf96
chromosome 9 open reading frame 96
chrX_-_49089771 0.70 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr18_-_5892103 0.67 ENST00000383490.2
TMEM200C
transmembrane protein 200C
chr7_+_64126503 0.67 ENST00000360117.3
ZNF107
zinc finger protein 107
chr9_-_35112376 0.62 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr19_-_22605136 0.60 ENST00000357774.5
ENST00000601553.1
ENST00000593657.1
ZNF98
zinc finger protein 98
chrX_+_16964794 0.59 ENST00000357277.3
REPS2
RALBP1 associated Eps domain containing 2
chr3_+_48413709 0.58 ENST00000296438.5
ENST00000436231.1
ENST00000445170.1
ENST00000415155.1
FBXW12
F-box and WD repeat domain containing 12
chr9_+_139221880 0.58 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr5_-_43313269 0.58 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_-_3599327 0.57 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599492 0.56 ENST00000435558.1
ENST00000345901.3
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_+_43922241 0.55 ENST00000329196.5
SPPL2C
signal peptide peptidase like 2C
chr18_-_44336998 0.55 ENST00000315087.7
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr9_+_136243117 0.54 ENST00000426926.2
ENST00000371957.3
C9orf96
chromosome 9 open reading frame 96
chr17_+_6899366 0.54 ENST00000251535.6
ALOX12
arachidonate 12-lipoxygenase
chr19_+_21264943 0.52 ENST00000597424.1
ZNF714
zinc finger protein 714
chr19_+_21203426 0.52 ENST00000261560.5
ENST00000599548.1
ENST00000594110.1
ZNF430
zinc finger protein 430
chr3_-_45957088 0.51 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_-_6557156 0.51 ENST00000537245.1
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr8_-_110660975 0.50 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr19_+_38880695 0.50 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr1_-_240906911 0.49 ENST00000431139.2
RP11-80B9.4
RP11-80B9.4
chr19_-_58071201 0.49 ENST00000325134.5
ENST00000457177.1
ZNF550
zinc finger protein 550
chr5_-_43313574 0.48 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_+_94139105 0.47 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr3_-_52002403 0.47 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr2_+_63816087 0.47 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr1_+_197382957 0.46 ENST00000367397.1
CRB1
crumbs homolog 1 (Drosophila)
chr19_-_58071166 0.46 ENST00000601415.1
ZNF550
zinc finger protein 550
chr2_-_73053126 0.45 ENST00000272427.6
ENST00000410104.1
EXOC6B
exocyst complex component 6B
chr10_+_11047259 0.43 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr2_+_63816295 0.42 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr11_+_46366799 0.42 ENST00000532868.2
DGKZ
diacylglycerol kinase, zeta
chr11_+_327171 0.41 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr2_+_63816126 0.40 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr4_-_82965397 0.39 ENST00000512716.1
ENST00000514050.1
ENST00000512343.1
ENST00000510780.1
ENST00000508294.1
RASGEF1B
RP11-689K5.3
RasGEF domain family, member 1B
RP11-689K5.3
chr17_-_72588422 0.39 ENST00000375352.1
CD300LD
CD300 molecule-like family member d
chr11_+_46366918 0.38 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr19_+_21264980 0.37 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr13_+_113623509 0.37 ENST00000535094.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr2_+_63816269 0.36 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr19_+_21265028 0.35 ENST00000291770.7
ZNF714
zinc finger protein 714
chr6_+_76458909 0.35 ENST00000369981.3
ENST00000369985.4
MYO6
myosin VI
chr11_+_125365110 0.34 ENST00000527818.1
AP000708.1
AP000708.1
chr20_-_21086975 0.34 ENST00000420705.1
ENST00000593272.1
LINC00237
long intergenic non-protein coding RNA 237
chr1_-_38218577 0.33 ENST00000540011.1
EPHA10
EPH receptor A10
chr19_+_22235310 0.33 ENST00000600162.1
ZNF257
zinc finger protein 257
chr17_+_6900201 0.33 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr6_-_27440837 0.32 ENST00000211936.6
ZNF184
zinc finger protein 184
chr14_-_50999190 0.31 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_+_4606347 0.29 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr11_-_117170403 0.28 ENST00000504995.1
BACE1
beta-site APP-cleaving enzyme 1
chr19_+_22235279 0.28 ENST00000594363.1
ENST00000597927.1
ENST00000594947.1
ZNF257
zinc finger protein 257
chr14_-_24733444 0.27 ENST00000560478.1
ENST00000560443.1
TGM1
transglutaminase 1
chr8_+_101162812 0.26 ENST00000353107.3
ENST00000522439.1
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr22_-_37880543 0.24 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_21203481 0.24 ENST00000595401.1
ZNF430
zinc finger protein 430
chr13_+_113622757 0.24 ENST00000375604.2
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_150944411 0.23 ENST00000368949.4
CERS2
ceramide synthase 2
chr6_+_76458990 0.22 ENST00000369977.3
MYO6
myosin VI
chr2_+_203776937 0.22 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF
calcium responsive transcription factor
chr1_+_168250194 0.22 ENST00000367821.3
TBX19
T-box 19
chr7_-_37488547 0.22 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr19_-_43702231 0.22 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr13_+_113622810 0.21 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_+_62809239 0.20 ENST00000456890.1
AC006455.1
AC006455.1
chr19_-_52035044 0.20 ENST00000359982.4
ENST00000436458.1
ENST00000425629.3
ENST00000391797.3
ENST00000343300.4
SIGLEC6
sialic acid binding Ig-like lectin 6
chr6_+_63921351 0.20 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr17_-_59940705 0.20 ENST00000577913.1
BRIP1
BRCA1 interacting protein C-terminal helicase 1
chr15_-_81282133 0.19 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr16_+_71392616 0.19 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr14_-_50999307 0.18 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_-_48723268 0.17 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
NCKIPSD
NCK interacting protein with SH3 domain
chr10_+_47658234 0.17 ENST00000447511.2
ENST00000537271.1
ANTXRL
anthrax toxin receptor-like
chr22_-_28316116 0.16 ENST00000415296.1
PITPNB
phosphatidylinositol transfer protein, beta
chr1_+_159796589 0.16 ENST00000368104.4
SLAMF8
SLAM family member 8
chr19_-_19932501 0.16 ENST00000540806.2
ENST00000590766.1
ENST00000587452.1
ENST00000545006.1
ENST00000590319.1
ENST00000587461.1
ENST00000450683.2
ENST00000443905.2
ENST00000590274.1
ZNF506
CTC-559E9.4
zinc finger protein 506
CTC-559E9.4
chr19_-_14629224 0.15 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr19_-_12833164 0.15 ENST00000356861.5
TNPO2
transportin 2
chr19_-_38806390 0.15 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_+_159796534 0.15 ENST00000289707.5
SLAMF8
SLAM family member 8
chr7_+_45039783 0.15 ENST00000258781.6
ENST00000541586.1
ENST00000544363.1
CCM2
cerebral cavernous malformation 2
chr1_+_161719552 0.14 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr12_-_123755639 0.14 ENST00000535979.1
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr1_-_11865982 0.14 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr18_-_19284724 0.12 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr6_-_135424186 0.12 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr19_-_12833361 0.11 ENST00000592287.1
TNPO2
transportin 2
chr1_+_44399347 0.11 ENST00000477048.1
ENST00000471394.2
ARTN
artemin
chr17_+_39394250 0.10 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr19_-_38806560 0.10 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr19_-_42927251 0.10 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr19_-_38806540 0.09 ENST00000592694.1
YIF1B
Yip1 interacting factor homolog B (S. cerevisiae)
chr9_+_116343192 0.08 ENST00000471324.2
RGS3
regulator of G-protein signaling 3
chr1_+_111992064 0.08 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr19_-_23578220 0.08 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
ZNF91
zinc finger protein 91
chr5_+_171200656 0.07 ENST00000524175.1
CTB-78H18.1
Uncharacterized protein
chr16_+_77225071 0.07 ENST00000439557.2
ENST00000545553.1
MON1B
MON1 secretory trafficking family member B
chr9_-_37592561 0.06 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
TOMM5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr19_-_23433144 0.05 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
ZNF724P
zinc finger protein 724, pseudogene
chr15_-_65903512 0.04 ENST00000567923.1
VWA9
von Willebrand factor A domain containing 9
chr7_-_44229022 0.04 ENST00000403799.3
GCK
glucokinase (hexokinase 4)
chr22_+_27017921 0.02 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr12_-_110883346 0.02 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr14_-_23770683 0.02 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E
protein phosphatase 1, regulatory subunit 3E
chr16_+_30006615 0.01 ENST00000563197.1
INO80E
INO80 complex subunit E

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1D1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0050894 determination of affect(GO:0050894)
0.9 6.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.6 1.9 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.3 1.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of translational initiation by iron(GO:0045994) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 14.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 0.7 GO:0042704 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.9 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.2 1.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 0.5 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 2.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.7 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 1.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.0 GO:0001878 response to yeast(GO:0001878)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.7 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.9 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.2 GO:0014011 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 1.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 1.6 GO:0035640 exploration behavior(GO:0035640)
0.0 0.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 2.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.8 GO:0035809 regulation of urine volume(GO:0035809)
0.0 1.6 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 1.5 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.5 GO:0035767 endothelial cell chemotaxis(GO:0035767)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 13.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 3.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.4 1.7 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.4 1.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.9 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.2 0.6 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 12.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.1 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.8 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 6.5 GO:0015631 tubulin binding(GO:0015631)
0.0 2.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK