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Illumina Body Map 2, young vs old

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Results for NR2E1

Z-value: 0.94

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
ENSG00000112333.7 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg19_v2_chr6_+_108487245_108487262-0.134.8e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_114874727 3.64 ENST00000543070.1
plastin 3
chr6_-_46922659 3.61 ENST00000265417.7
G protein-coupled receptor 116
chr1_+_185703513 3.36 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chr9_-_16728161 3.26 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr12_-_91539918 3.26 ENST00000548218.1
decorin
chr3_-_64673668 3.23 ENST00000498707.1
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr7_+_116166331 3.16 ENST00000393468.1
ENST00000393467.1
caveolin 1, caveolae protein, 22kDa
chr12_-_91572278 3.12 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
decorin
chr3_-_64673289 3.11 ENST00000295903.4
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr8_-_86253888 3.00 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr17_-_66951474 3.00 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chrX_-_73061339 2.84 ENST00000602863.1
X inactive specific transcript (non-protein coding)
chr6_+_31916733 2.77 ENST00000483004.1
complement factor B
chr9_-_95166976 2.71 ENST00000447356.1
osteoglycin
chr17_+_12569306 2.57 ENST00000425538.1
myocardin
chr9_-_95166884 2.56 ENST00000375561.5
osteoglycin
chr17_-_66951382 2.56 ENST00000586539.1
ATP-binding cassette, sub-family A (ABC1), member 8
chr3_-_64673656 2.56 ENST00000459780.1
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr3_-_112356944 2.55 ENST00000461431.1
coiled-coil domain containing 80
chr7_-_107443652 2.54 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr12_+_54384370 2.54 ENST00000504315.1
homeobox C6
chr9_-_95166841 2.53 ENST00000262551.4
osteoglycin
chr12_+_7169887 2.53 ENST00000542978.1
complement component 1, s subcomponent
chr5_-_33892204 2.50 ENST00000504830.1
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr17_-_46667594 2.49 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
homeobox B3
chr2_+_192141611 2.46 ENST00000392316.1
myosin IB
chr3_-_93747425 2.45 ENST00000315099.2
syntaxin 19
chr13_+_110958124 2.39 ENST00000400163.2
collagen, type IV, alpha 2
chr3_-_148939598 2.35 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr1_-_116311402 2.27 ENST00000261448.5
calsequestrin 2 (cardiac muscle)
chr11_-_111794446 2.19 ENST00000527950.1
crystallin, alpha B
chr3_-_116164306 2.17 ENST00000490035.2
limbic system-associated membrane protein
chr17_-_46667628 2.13 ENST00000498678.1
homeobox B3
chr4_+_71063641 2.08 ENST00000514097.1
odontogenic, ameloblast asssociated
chr3_+_12392971 2.07 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr5_-_42811986 2.01 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr16_-_10652993 1.99 ENST00000536829.1
epithelial membrane protein 2
chr1_+_32042105 1.98 ENST00000457433.2
ENST00000441210.2
tubulointerstitial nephritis antigen-like 1
chr7_+_142829162 1.94 ENST00000291009.3
prolactin-induced protein
chr1_-_116311323 1.93 ENST00000456138.2
calsequestrin 2 (cardiac muscle)
chr5_+_32711829 1.90 ENST00000415167.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr4_-_76008706 1.89 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
chr5_-_33892118 1.87 ENST00000515401.1
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr12_-_53343633 1.83 ENST00000546826.1
keratin 8
chr17_+_12626199 1.76 ENST00000609971.1
AC005358.1
chr9_-_119162885 1.75 ENST00000445861.2
PAPPA antisense RNA 1
chr12_-_71031185 1.68 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chrX_-_128657457 1.67 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chrX_-_33146477 1.65 ENST00000378677.2
dystrophin
chr5_-_149516966 1.63 ENST00000517957.1
platelet-derived growth factor receptor, beta polypeptide
chr5_+_9546306 1.62 ENST00000508179.1
small nucleolar RNA host gene 18 (non-protein coding)
chr1_+_170633047 1.62 ENST00000239461.6
ENST00000497230.2
paired related homeobox 1
chr3_-_168864315 1.60 ENST00000475754.1
ENST00000484519.1
MDS1 and EVI1 complex locus
chr5_+_32711419 1.56 ENST00000265074.8
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr5_-_33892046 1.56 ENST00000352040.3
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr9_+_87285539 1.56 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr9_-_95298927 1.55 ENST00000395534.2
extracellular matrix protein 2, female organ and adipocyte specific
chr8_+_24241969 1.54 ENST00000522298.1
ADAM-like, decysin 1
chr2_-_183291741 1.52 ENST00000351439.5
ENST00000409365.1
phosphodiesterase 1A, calmodulin-dependent
chr8_-_122653630 1.51 ENST00000303924.4
hyaluronan synthase 2
chr1_+_159141397 1.51 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
cell adhesion molecule 3
chr12_-_71031220 1.49 ENST00000334414.6
protein tyrosine phosphatase, receptor type, B
chr13_+_28527647 1.47 ENST00000567234.1
long intergenic non-protein coding RNA 543
chr12_-_50643664 1.46 ENST00000550592.1
LIM domain and actin binding 1
chr8_+_24241789 1.44 ENST00000256412.4
ENST00000538205.1
ADAM-like, decysin 1
chr10_+_85933494 1.44 ENST00000372126.3
chromosome 10 open reading frame 99
chr9_-_16727978 1.43 ENST00000418777.1
ENST00000468187.2
basonuclin 2
chr14_+_67656110 1.43 ENST00000524532.1
ENST00000530728.1
family with sequence similarity 71, member D
chr11_+_31833939 1.41 ENST00000530348.1
reticulocalbin 1, EF-hand calcium binding domain
chr3_-_116163830 1.39 ENST00000333617.4
limbic system-associated membrane protein
chr2_-_183387064 1.38 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr7_+_70597109 1.34 ENST00000333538.5
Williams-Beuren syndrome chromosome region 17
chr12_+_56624436 1.34 ENST00000266980.4
ENST00000437277.1
solute carrier family 39 (zinc transporter), member 5
chr8_+_11561660 1.32 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA binding protein 4
chr3_-_148939835 1.31 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr6_+_125540951 1.30 ENST00000524679.1
tumor protein D52-like 1
chr5_+_9546376 1.30 ENST00000509788.1
small nucleolar RNA host gene 18 (non-protein coding)
chr4_-_175041663 1.29 ENST00000503140.1
RP11-148L24.1
chr4_+_77177512 1.29 ENST00000606246.1
family with sequence similarity 47, member E
chr4_-_47983519 1.28 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
cyclic nucleotide gated channel alpha 1
chr11_-_102714534 1.27 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_-_168864427 1.26 ENST00000468789.1
MDS1 and EVI1 complex locus
chr8_+_104384616 1.26 ENST00000520337.1
collagen triple helix repeat containing 1
chr1_+_240408560 1.26 ENST00000441342.1
ENST00000545751.1
formin 2
chr17_+_12569472 1.26 ENST00000343344.4
myocardin
chr2_-_106013400 1.25 ENST00000409807.1
four and a half LIM domains 2
chr12_-_56236711 1.24 ENST00000409200.3
matrix metallopeptidase 19
chr8_+_76452097 1.24 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr4_+_96012614 1.22 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr12_-_28124903 1.22 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr8_+_80523962 1.19 ENST00000518491.1
stathmin-like 2
chr6_-_41715128 1.19 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
progastricsin (pepsinogen C)
chr1_+_212738676 1.18 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr7_-_14026123 1.18 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chr12_-_52887034 1.17 ENST00000330722.6
keratin 6A
chr4_-_135122903 1.14 ENST00000421491.3
ENST00000529122.2
poly(A) binding protein, cytoplasmic 4-like
chr3_+_113616317 1.14 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr9_-_95244781 1.14 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
asporin
chr11_+_100784231 1.12 ENST00000531183.1
Rho GTPase activating protein 42
chr20_-_22559211 1.11 ENST00000564492.1
long intergenic non-protein coding RNA 261
chr12_+_64238539 1.11 ENST00000357825.3
SLIT-ROBO Rho GTPase activating protein 1
chr4_-_13546632 1.11 ENST00000382438.5
NK3 homeobox 2
chr11_-_111781554 1.10 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr7_+_116312411 1.10 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
met proto-oncogene
chrX_-_65259914 1.09 ENST00000374737.4
ENST00000455586.2
V-set and immunoglobulin domain containing 4
chr5_-_160279207 1.07 ENST00000327245.5
ATPase, class V, type 10B
chr12_-_24102576 1.07 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SRY (sex determining region Y)-box 5
chr12_-_56236690 1.06 ENST00000322569.4
matrix metallopeptidase 19
chr9_-_91793675 1.06 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr7_+_114055052 1.05 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
forkhead box P2
chr5_+_125706998 1.05 ENST00000506445.1
GRAM domain containing 3
chr14_+_37131058 1.05 ENST00000361487.6
paired box 9
chr8_+_77593474 1.04 ENST00000455469.2
ENST00000050961.6
zinc finger homeobox 4
chr14_+_51955831 1.04 ENST00000356218.4
FERM domain containing 6
chr6_-_138866823 1.04 ENST00000342260.5
NHS-like 1
chr14_+_69865401 1.03 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
solute carrier family 39, member 9
chr19_-_47157914 1.03 ENST00000300875.4
dishevelled-binding antagonist of beta-catenin 3
chr20_-_22565101 1.02 ENST00000419308.2
forkhead box A2
chr12_-_56236734 1.02 ENST00000548629.1
matrix metallopeptidase 19
chrX_-_65259900 1.01 ENST00000412866.2
V-set and immunoglobulin domain containing 4
chr17_+_1959369 1.00 ENST00000576444.1
ENST00000322941.3
hypermethylated in cancer 1
chr10_-_21786179 0.99 ENST00000377113.5
cancer susceptibility candidate 10
chr11_-_111781454 0.99 ENST00000533280.1
crystallin, alpha B
chr2_+_177015950 0.99 ENST00000306324.3
homeobox D4
chr6_+_148663729 0.98 ENST00000367467.3
SAM and SH3 domain containing 1
chrX_-_65253506 0.98 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr17_-_67057203 0.98 ENST00000340001.4
ATP-binding cassette, sub-family A (ABC1), member 9
chr5_+_140743859 0.98 ENST00000518069.1
protocadherin gamma subfamily A, 5
chr7_-_16505440 0.96 ENST00000307068.4
sclerostin domain containing 1
chr1_-_227505289 0.96 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr3_+_108855558 0.95 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
chr6_+_142623758 0.95 ENST00000541199.1
ENST00000435011.2
G protein-coupled receptor 126
chr17_-_26695013 0.94 ENST00000555059.2
Homeobox protein SEBOX
chr11_-_8832182 0.94 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
suppression of tumorigenicity 5
chr5_+_39520499 0.94 ENST00000604954.1
CTD-2078B5.2
chr4_+_52917451 0.94 ENST00000295213.4
ENST00000419395.2
spermatogenesis associated 18
chr2_+_101437487 0.93 ENST00000427413.1
ENST00000542504.1
neuronal PAS domain protein 2
chr6_+_143447322 0.92 ENST00000458219.1
androgen-induced 1
chr17_-_67057114 0.92 ENST00000370732.2
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_136676707 0.90 ENST00000329582.4
interleukin 20 receptor beta
chr15_-_88799384 0.89 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
neurotrophic tyrosine kinase, receptor, type 3
chr9_+_1050331 0.88 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
doublesex and mab-3 related transcription factor 2
chr11_-_5271122 0.88 ENST00000330597.3
hemoglobin, gamma A
chr6_+_54173227 0.87 ENST00000259782.4
ENST00000370864.3
tubulointerstitial nephritis antigen
chr5_-_135290651 0.86 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr12_-_91546926 0.86 ENST00000550758.1
decorin
chr7_+_80267949 0.86 ENST00000482059.2
CD36 molecule (thrombospondin receptor)
chr5_-_9546180 0.85 ENST00000382496.5
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_-_57004658 0.84 ENST00000606794.1
apelin receptor
chr4_-_141348999 0.84 ENST00000325617.5
calmegin
chr6_+_12290586 0.84 ENST00000379375.5
endothelin 1
chr2_-_118943930 0.83 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr20_-_7238861 0.83 ENST00000428954.1
RP11-19D2.1
chr4_+_183370146 0.83 ENST00000510504.1
teneurin transmembrane protein 3
chr2_+_74685527 0.82 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WW domain binding protein 1
chr18_-_22804637 0.82 ENST00000577775.1
zinc finger protein 521
chrX_-_114253536 0.82 ENST00000371936.1
interleukin 13 receptor, alpha 2
chr2_-_169887827 0.82 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chrX_+_135614293 0.82 ENST00000370634.3
vestigial like 1 (Drosophila)
chr12_-_75784669 0.81 ENST00000552497.1
ENST00000551829.1
ENST00000436898.1
ENST00000442339.2
calcyphosine 2
chr10_-_21463116 0.80 ENST00000417816.2
nebulette
chr14_-_103434869 0.80 ENST00000559043.1
CDC42 binding protein kinase beta (DMPK-like)
chr20_+_32782375 0.80 ENST00000568305.1
agouti signaling protein
chr3_+_42897512 0.79 ENST00000493193.1
atypical chemokine receptor 2
chr3_+_148508845 0.79 ENST00000491148.1
carboxypeptidase B1 (tissue)
chr13_-_49975632 0.79 ENST00000457041.1
ENST00000355854.4
calcium binding protein 39-like
chr17_-_26694979 0.79 ENST00000438614.1
vitronectin
chr12_+_80603233 0.79 ENST00000547103.1
ENST00000458043.2
otogelin-like
chr15_-_51535208 0.78 ENST00000405913.3
ENST00000559878.1
cytochrome P450, family 19, subfamily A, polypeptide 1
chr1_+_77333117 0.77 ENST00000477717.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_-_231989808 0.76 ENST00000258400.3
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr5_-_82969405 0.76 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr7_+_134671234 0.75 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
ATP/GTP binding protein-like 3
chr16_-_66952779 0.74 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr6_+_74405501 0.74 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr3_-_50360192 0.73 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
hyaluronoglucosaminidase 2
chr2_-_183387283 0.73 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr6_-_138820624 0.72 ENST00000343505.5
NHS-like 1
chr12_+_26348582 0.72 ENST00000535504.1
sarcospan
chr1_+_152850787 0.72 ENST00000368765.3
sperm mitochondria-associated cysteine-rich protein
chr9_-_75567962 0.72 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr18_+_6774000 0.71 ENST00000532723.1
Rho GTPase activating protein 28
chr3_-_24536453 0.70 ENST00000453729.2
ENST00000413780.1
thyroid hormone receptor, beta
chr2_+_201173667 0.68 ENST00000409755.3
spermatogenesis associated, serine-rich 2-like
chr3_+_46616017 0.68 ENST00000542931.1
teratocarcinoma-derived growth factor 1
chr7_-_8301768 0.67 ENST00000265577.7
islet cell autoantigen 1, 69kDa
chr12_-_82152444 0.67 ENST00000549325.1
ENST00000550584.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr3_+_69788576 0.66 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr17_-_67057047 0.65 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_+_126315091 0.65 ENST00000335110.5
FAT atypical cadherin 4
chr17_+_19186292 0.64 ENST00000395626.1
ENST00000571254.1
epsin 2
chr1_-_169703203 0.63 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr2_-_207630033 0.62 ENST00000449792.1
malate dehydrogenase 1B, NAD (soluble)
chr5_+_71475449 0.62 ENST00000504492.1
microtubule-associated protein 1B
chr4_-_111119804 0.62 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr16_-_77465450 0.62 ENST00000562345.1
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr7_+_80267973 0.62 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr17_-_42327236 0.62 ENST00000399246.2
AC003102.1
chrX_+_115301975 0.62 ENST00000371906.4
angiotensin II receptor, type 2
chr5_+_127873657 0.62 ENST00000508645.1
solute carrier family 27 (fatty acid transporter), member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:2001112 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
1.1 3.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.0 3.8 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.6 4.6 GO:0021546 rhombomere development(GO:0021546)
0.5 1.6 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.5 2.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 7.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.5 2.8 GO:0070295 renal water absorption(GO:0070295)
0.5 8.9 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.4 0.8 GO:0030185 nitric oxide transport(GO:0030185)
0.4 1.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.4 2.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.4 1.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 5.6 GO:0042908 xenobiotic transport(GO:0042908)
0.3 7.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 1.3 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.3 3.3 GO:0001554 luteolysis(GO:0001554)
0.3 4.2 GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.3 1.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 1.2 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.3 1.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.3 1.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.3 1.6 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 5.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.2 1.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 0.9 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 0.9 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 2.0 GO:0070836 caveola assembly(GO:0070836)
0.2 2.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 1.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.6 GO:0035566 negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.2 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.2 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.8 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 3.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 0.7 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 3.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 4.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.8 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.2 0.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 1.0 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 0.5 GO:0090427 activation of meiosis(GO:0090427)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 0.8 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.7 GO:0008050 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.1 1.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.4 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.1 1.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 3.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 4.7 GO:0003416 endochondral bone growth(GO:0003416)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 1.5 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 1.0 GO:0003383 apical constriction(GO:0003383)
0.1 0.8 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 3.7 GO:0006825 copper ion transport(GO:0006825)
0.1 1.7 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 1.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 0.2 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.1 1.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 2.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.7 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 2.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.7 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.9 GO:0048021 regulation of melanin biosynthetic process(GO:0048021) negative regulation of melanin biosynthetic process(GO:0048022) regulation of secondary metabolite biosynthetic process(GO:1900376) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.6 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 2.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.8 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 1.2 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.7 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 2.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 1.7 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 0.7 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.6 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.9 GO:0051775 response to redox state(GO:0051775)
0.0 3.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.0 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 1.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:1903414 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.6 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 3.9 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.2 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 1.5 GO:0031529 ruffle organization(GO:0031529)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 1.1 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.8 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.9 GO:0006897 endocytosis(GO:0006897)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 1.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 1.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 4.2 GO:0030314 junctional membrane complex(GO:0030314)
0.3 2.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 4.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 1.7 GO:0016589 NURF complex(GO:0016589)
0.1 1.7 GO:0016013 syntrophin complex(GO:0016013)
0.1 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.8 GO:0042641 actomyosin(GO:0042641)
0.1 2.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.5 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.3 GO:0071745 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 2.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 7.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 4.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 17.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.2 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 6.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0042383 sarcolemma(GO:0042383)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 4.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 1.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.8 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.8 0.8 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.5 3.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 3.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.4 5.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 1.6 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.4 3.0 GO:0004064 arylesterase activity(GO:0004064)
0.3 1.5 GO:0070052 collagen V binding(GO:0070052)
0.3 3.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 1.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.3 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.3 1.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 1.9 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 1.0 GO:0098821 BMP receptor activity(GO:0098821)
0.2 1.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.2 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 4.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 2.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 3.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 22.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.8 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 1.0 GO:0005497 androgen binding(GO:0005497)
0.1 2.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.9 GO:0019864 IgG binding(GO:0019864)
0.1 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 3.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.8 GO:0001848 complement binding(GO:0001848)
0.1 1.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 3.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.9 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.3 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 7.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 5.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 2.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 2.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 3.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 7.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 5.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 23.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 4.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.4 7.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 7.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 5.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 2.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 8.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.6 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 5.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules