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Illumina Body Map 2, young vs old

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Results for NR4A1

Z-value: 0.31

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Transcription factors associated with NR4A1

Gene Symbol Gene ID Gene Info
NR4A1
ENSG00000123358.15 nuclear receptor subfamily 4 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A1hg19_v2_chr12_+_52431016_524310710.144.6e-01Click!

Activity profile of NR4A1 motif

Sorted Z-values of NR4A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_4854375 6.26 ENST00000521811.1
ENST00000519602.1
ENST00000323997.6
ENST00000522249.1
ENST00000519584.1
ENO3
enolase 3 (beta, muscle)
chr17_+_4855053 5.72 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr12_+_109577202 3.70 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr1_-_9563433 3.49 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr11_+_116700614 3.10 ENST00000375345.1
APOC3
apolipoprotein C-III
chr1_+_236849754 3.07 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr11_+_116700600 3.03 ENST00000227667.3
APOC3
apolipoprotein C-III
chr6_+_53948328 2.98 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr1_+_64059332 2.89 ENST00000540265.1
PGM1
phosphoglucomutase 1
chr19_+_4153598 2.53 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr6_+_53948221 2.50 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr3_+_46538981 2.23 ENST00000296142.3
RTP3
receptor (chemosensory) transporter protein 3
chrX_+_2746818 2.21 ENST00000398806.3
GYG2
glycogenin 2
chrX_+_2746850 2.12 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr10_-_74714533 1.89 ENST00000373032.3
PLA2G12B
phospholipase A2, group XIIB
chr4_-_111563076 1.78 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr4_-_65275100 1.58 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr20_+_3052264 1.55 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr4_-_111563279 1.54 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr14_-_20903801 1.50 ENST00000344581.4
KLHL33
kelch-like family member 33
chr6_+_44126545 1.48 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
CAPN11
calpain 11
chr17_+_1646130 1.42 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr14_+_38065052 1.24 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr10_+_101542462 1.21 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_+_133561725 1.21 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr11_+_7618413 1.15 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_127039075 1.15 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr4_-_65275162 1.13 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr4_+_100495864 1.09 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr6_+_31895467 1.08 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chrX_-_43741594 1.07 ENST00000536181.1
ENST00000378069.4
MAOB
monoamine oxidase B
chr1_+_16062820 1.07 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr18_-_5197501 1.07 ENST00000580650.1
C18orf42
chromosome 18 open reading frame 42
chr11_-_111794446 1.05 ENST00000527950.1
CRYAB
crystallin, alpha B
chr20_+_12989895 1.02 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr11_+_86748957 1.02 ENST00000526733.1
ENST00000532959.1
TMEM135
transmembrane protein 135
chr12_+_6644443 1.01 ENST00000396858.1
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr22_-_51016846 0.98 ENST00000312108.7
ENST00000395650.2
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr6_-_116381918 0.96 ENST00000606080.1
FRK
fyn-related kinase
chr7_-_107443652 0.93 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr20_-_42815733 0.93 ENST00000342272.3
JPH2
junctophilin 2
chr11_+_86749035 0.90 ENST00000305494.5
ENST00000535167.1
TMEM135
transmembrane protein 135
chr4_-_89744457 0.90 ENST00000395002.2
FAM13A
family with sequence similarity 13, member A
chr11_+_86748863 0.88 ENST00000340353.7
TMEM135
transmembrane protein 135
chr1_-_197036364 0.87 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr5_-_124084493 0.86 ENST00000509799.1
ZNF608
zinc finger protein 608
chr6_+_31895480 0.86 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr10_+_12110963 0.86 ENST00000263035.4
ENST00000437298.1
DHTKD1
dehydrogenase E1 and transketolase domain containing 1
chr19_+_13134772 0.86 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_61869748 0.85 ENST00000357977.5
NFIA
nuclear factor I/A
chr14_-_21566731 0.84 ENST00000360947.3
ZNF219
zinc finger protein 219
chr22_-_51017084 0.83 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr19_+_49713991 0.80 ENST00000597316.1
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr3_+_29322437 0.80 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr20_-_42816206 0.80 ENST00000372980.3
JPH2
junctophilin 2
chr3_+_184038073 0.79 ENST00000428387.1
ENST00000434061.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr15_-_42783303 0.76 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr12_-_118490403 0.76 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr3_+_184037466 0.76 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr15_+_36887069 0.75 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
C15orf41
chromosome 15 open reading frame 41
chr5_-_126409159 0.74 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr17_-_7307358 0.74 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
TMEM256
TMEM256-PLSCR3
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_+_159593271 0.73 ENST00000512251.1
ENST00000511912.1
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr7_+_6048856 0.70 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr11_-_8680383 0.70 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr12_+_58335360 0.70 ENST00000300145.3
XRCC6BP1
XRCC6 binding protein 1
chr7_-_229557 0.70 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr16_+_691792 0.69 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr12_+_54378923 0.68 ENST00000303460.4
HOXC10
homeobox C10
chr12_+_54378849 0.66 ENST00000515593.1
HOXC10
homeobox C10
chr13_-_30881134 0.65 ENST00000380617.3
ENST00000441394.1
KATNAL1
katanin p60 subunit A-like 1
chrX_+_114874727 0.64 ENST00000543070.1
PLS3
plastin 3
chr6_+_31895287 0.64 ENST00000447952.2
C2
complement component 2
chr20_+_12989596 0.64 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr17_+_7123125 0.63 ENST00000356839.5
ENST00000583312.1
ENST00000350303.5
ACADVL
acyl-CoA dehydrogenase, very long chain
chr17_+_7123207 0.63 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr5_-_142784003 0.63 ENST00000416954.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_-_48936272 0.62 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr10_-_128359074 0.61 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr19_+_17416457 0.61 ENST00000252602.1
MRPL34
mitochondrial ribosomal protein L34
chr4_-_89744365 0.60 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr6_+_31895254 0.60 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr5_+_73109339 0.59 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr8_+_145065705 0.59 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_+_26353664 0.59 ENST00000531646.1
ANO3
anoctamin 3
chr5_+_121187625 0.58 ENST00000321339.1
FTMT
ferritin mitochondrial
chr4_-_89744314 0.57 ENST00000508369.1
FAM13A
family with sequence similarity 13, member A
chr4_-_74088800 0.56 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr12_+_21679220 0.55 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr6_-_43595039 0.55 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr19_-_11639931 0.55 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr19_+_14138960 0.55 ENST00000431365.2
ENST00000585987.1
RLN3
relaxin 3
chr20_+_12989822 0.55 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr14_-_21567009 0.54 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr18_-_5197224 0.54 ENST00000434239.3
C18orf42
chromosome 18 open reading frame 42
chr12_-_118490217 0.51 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chrX_-_54824673 0.51 ENST00000218436.6
ITIH6
inter-alpha-trypsin inhibitor heavy chain family, member 6
chr22_-_31364187 0.48 ENST00000215862.4
ENST00000397641.3
MORC2
MORC family CW-type zinc finger 2
chr19_+_17416609 0.48 ENST00000602206.1
MRPL34
mitochondrial ribosomal protein L34
chr11_+_3877412 0.47 ENST00000527651.1
STIM1
stromal interaction molecule 1
chr2_-_207024134 0.47 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr17_-_36499693 0.47 ENST00000342292.4
GPR179
G protein-coupled receptor 179
chr13_-_74993252 0.45 ENST00000325811.1
AL355390.1
Uncharacterized protein
chr6_+_108616243 0.45 ENST00000421954.1
LACE1
lactation elevated 1
chr19_-_11639910 0.45 ENST00000588998.1
ENST00000586149.1
ECSIT
ECSIT signalling integrator
chr8_+_145065521 0.45 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr18_+_43753974 0.44 ENST00000282059.6
ENST00000321319.6
C18orf25
chromosome 18 open reading frame 25
chr19_+_6372444 0.43 ENST00000245812.3
ALKBH7
alkB, alkylation repair homolog 7 (E. coli)
chr11_-_113577052 0.43 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr14_+_35591509 0.43 ENST00000604073.1
KIAA0391
KIAA0391
chr16_+_53241854 0.40 ENST00000565803.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_+_79670386 0.40 ENST00000333676.3
ENST00000571730.1
ENST00000541223.1
MRPL12
SLC25A10
SLC25A10
mitochondrial ribosomal protein L12
Mitochondrial dicarboxylate carrier; Uncharacterized protein; cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_+_175199674 0.40 ENST00000394967.2
SP9
Sp9 transcription factor
chr4_-_40632757 0.40 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr9_-_75567962 0.39 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr22_+_24891210 0.39 ENST00000382760.2
UPB1
ureidopropionase, beta
chr11_+_64073699 0.37 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr10_-_75351088 0.37 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr7_+_119913688 0.36 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr14_+_35591020 0.35 ENST00000603611.1
KIAA0391
KIAA0391
chr12_-_16758835 0.34 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_-_28896641 0.31 ENST00000543394.1
FLT1
fms-related tyrosine kinase 1
chr10_+_104005272 0.31 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr11_-_113577014 0.31 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chr20_+_17680599 0.31 ENST00000246090.5
BANF2
barrier to autointegration factor 2
chr11_+_3876859 0.30 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr1_+_165600436 0.29 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr1_+_173793777 0.29 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_+_176432298 0.28 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr12_+_50794891 0.28 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr3_+_138340049 0.28 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr11_+_66624527 0.27 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr5_-_142784101 0.27 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_+_21525818 0.27 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr13_-_30880979 0.26 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr4_+_57253672 0.26 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chr2_-_44223138 0.26 ENST00000260665.7
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr20_+_17680587 0.25 ENST00000427254.1
ENST00000377805.3
BANF2
barrier to autointegration factor 2
chr8_+_123793633 0.24 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr6_+_118869452 0.24 ENST00000357525.5
PLN
phospholamban
chr4_-_40632881 0.24 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr12_-_16758873 0.23 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_135612198 0.23 ENST00000589735.1
LUZP6
leucine zipper protein 6
chr17_-_66287310 0.23 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr17_-_66287257 0.22 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr2_-_207024233 0.21 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr4_+_71108300 0.20 ENST00000304954.3
CSN3
casein kappa
chr17_-_79283041 0.20 ENST00000332012.5
LINC00482
long intergenic non-protein coding RNA 482
chr5_-_142784888 0.20 ENST00000514699.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_53320245 0.18 ENST00000552150.1
KRT8
keratin 8
chr16_+_21312170 0.17 ENST00000338573.5
ENST00000561968.1
CRYM-AS1
CRYM antisense RNA 1
chr5_-_53115506 0.17 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1
CTD-2081C10.1
chr5_-_87564620 0.17 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr7_-_37488547 0.17 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr18_-_60986962 0.16 ENST00000333681.4
BCL2
B-cell CLL/lymphoma 2
chr12_+_50794947 0.16 ENST00000552445.1
LARP4
La ribonucleoprotein domain family, member 4
chr3_-_113464906 0.14 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_-_37488777 0.14 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr4_-_40632844 0.13 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr14_+_32476072 0.12 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chr3_-_44519131 0.12 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr8_+_99956662 0.12 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr2_+_26568965 0.11 ENST00000260585.7
ENST00000447170.1
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr11_-_111649074 0.11 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr14_+_35591735 0.11 ENST00000604948.1
ENST00000605201.1
ENST00000250377.7
ENST00000321130.10
ENST00000534898.4
KIAA0391
KIAA0391
chr7_-_37488834 0.10 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr7_-_6048650 0.10 ENST00000382321.4
ENST00000406569.3
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr12_+_32655110 0.10 ENST00000546442.1
ENST00000583694.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_156589051 0.09 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr8_-_9761693 0.09 ENST00000521863.1
LINC00599
long intergenic non-protein coding RNA 599
chr10_-_69991865 0.08 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr1_-_33777822 0.08 ENST00000330379.5
A3GALT2
alpha 1,3-galactosyltransferase 2
chr10_+_26986582 0.07 ENST00000376215.5
ENST00000376203.5
PDSS1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr14_-_35591679 0.07 ENST00000557278.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr8_+_133787586 0.07 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr1_-_161102367 0.06 ENST00000464113.1
DEDD
death effector domain containing
chr12_+_32655048 0.06 ENST00000427716.2
ENST00000266482.3
FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_120971882 0.05 ENST00000392793.1
TECTA
tectorin alpha
chr3_+_14989076 0.05 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr5_+_159895275 0.04 ENST00000517927.1
MIR146A
microRNA 146a
chr17_+_9745786 0.04 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr7_+_99933730 0.04 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr15_-_42565023 0.03 ENST00000566474.1
TMEM87A
transmembrane protein 87A
chr3_-_113465065 0.02 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_+_69942915 0.02 ENST00000604969.1
ENST00000603207.1
BAI3
brain-specific angiogenesis inhibitor 3
chr7_-_6048702 0.01 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr13_-_33112823 0.01 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr11_-_111649015 0.01 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr2_+_178257372 0.01 ENST00000264167.4
ENST00000409888.1
AGPS
alkylglycerone phosphate synthase

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.8 3.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.7 3.3 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.6 3.7 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.5 1.5 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.4 1.2 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.3 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.4 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.2 0.7 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 0.8 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 12.0 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.9 GO:0019388 galactose catabolic process(GO:0019388)
0.2 2.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 0.6 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.1 0.4 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 1.7 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 2.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 4.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 1.3 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 1.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.8 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.9 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 1.1 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.9 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.6 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.6 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.9 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 2.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 2.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.9 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 12.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.7 6.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 2.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.0 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.9 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 1.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 5.3 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 1.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 6.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.3 12.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 4.3 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.6 3.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.6 3.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.4 2.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 2.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 2.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.3 1.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.7 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 1.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 0.6 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.4 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 2.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.9 GO:0001848 complement binding(GO:0001848)
0.0 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 3.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 2.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 4.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 7.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 13.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 6.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 3.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)