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Illumina Body Map 2, young vs old

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Results for NR4A2

Z-value: 0.84

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
NR4A2
ENSG00000153234.9 nuclear receptor subfamily 4 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v2_chr2_-_157189180_157189290-0.222.4e-01Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_42744130 3.49 ENST00000417472.1
ENST00000442469.1
HHATL
hedgehog acyltransferase-like
chr3_-_42743006 3.19 ENST00000310417.5
HHATL
hedgehog acyltransferase-like
chr20_-_62130474 2.83 ENST00000217182.3
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_-_229569834 2.72 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr5_+_149569520 2.54 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr19_-_51289436 2.25 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chrX_-_21776281 2.06 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr16_+_6069586 2.01 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_58535372 1.99 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr16_-_4292071 1.90 ENST00000399609.3
SRL
sarcalumenin
chr11_-_47470591 1.84 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr12_-_114843889 1.81 ENST00000405440.2
TBX5
T-box 5
chr11_-_19223523 1.78 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr8_+_21911054 1.77 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr16_+_6069072 1.62 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_6069664 1.62 ENST00000422070.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_+_135230712 1.54 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr11_-_47470682 1.50 ENST00000529341.1
ENST00000352508.3
RAPSN
receptor-associated protein of the synapse
chr17_-_56358287 1.48 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr11_-_47470703 1.45 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr4_-_65275100 1.45 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr4_+_41614720 1.42 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr20_+_57875758 1.41 ENST00000395654.3
EDN3
endothelin 3
chr10_-_128359008 1.41 ENST00000488181.1
C10orf90
chromosome 10 open reading frame 90
chr20_+_57875457 1.38 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr17_-_42988004 1.37 ENST00000586125.1
ENST00000591880.1
GFAP
glial fibrillary acidic protein
chr17_-_29624343 1.34 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr3_+_159557637 1.32 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr10_-_128359074 1.27 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr15_-_42783303 1.27 ENST00000565380.1
ENST00000564754.1
ZNF106
zinc finger protein 106
chr4_-_65275162 1.27 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr12_-_16760021 1.23 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_80253387 1.23 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr11_-_790060 1.22 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr12_-_16760195 1.19 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_+_41614909 1.19 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr12_-_16759711 1.13 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_27503770 1.13 ENST00000533112.1
MYO18A
myosin XVIIIA
chr1_-_205904950 1.10 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr17_-_4889508 1.09 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr10_+_81065975 1.08 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr2_-_207024134 1.05 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr3_-_150966902 1.04 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr19_+_589893 1.01 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr9_+_95997205 0.99 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chr1_-_154164534 0.98 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chrX_-_153640420 0.96 ENST00000451865.1
ENST00000432135.1
ENST00000369809.1
ENST00000393638.1
ENST00000424626.1
ENST00000309585.5
DNASE1L1
deoxyribonuclease I-like 1
chr9_+_113431029 0.96 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK
muscle, skeletal, receptor tyrosine kinase
chr20_+_57875658 0.95 ENST00000371025.3
EDN3
endothelin 3
chr8_-_70745575 0.94 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_+_220299547 0.94 ENST00000312358.7
SPEG
SPEG complex locus
chr22_+_31518938 0.94 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_+_119616447 0.90 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr17_-_9939854 0.90 ENST00000584146.2
GAS7
growth arrest-specific 7
chr8_-_131028782 0.88 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr11_-_111794446 0.88 ENST00000527950.1
CRYAB
crystallin, alpha B
chrY_-_15591818 0.86 ENST00000382893.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr2_-_85895295 0.84 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr12_-_16758873 0.84 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_207023918 0.84 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr10_-_94301107 0.83 ENST00000436178.1
IDE
insulin-degrading enzyme
chr1_-_116311402 0.83 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr1_+_222913009 0.82 ENST00000456298.1
FAM177B
family with sequence similarity 177, member B
chrY_-_15591485 0.81 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr12_-_16759440 0.80 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_116311323 0.79 ENST00000456138.2
CASQ2
calsequestrin 2 (cardiac muscle)
chr7_+_142000747 0.77 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr19_+_3880581 0.77 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr11_-_66139199 0.74 ENST00000357440.2
SLC29A2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr17_-_9940058 0.74 ENST00000585266.1
GAS7
growth arrest-specific 7
chr16_-_745946 0.73 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr17_-_9939935 0.72 ENST00000580043.1
GAS7
growth arrest-specific 7
chr2_+_210288760 0.72 ENST00000199940.6
MAP2
microtubule-associated protein 2
chr10_-_61122934 0.70 ENST00000512919.1
FAM13C
family with sequence similarity 13, member C
chr14_-_61191049 0.70 ENST00000556952.3
SIX4
SIX homeobox 4
chr3_+_14989186 0.70 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr8_-_53626974 0.68 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr8_+_134125727 0.68 ENST00000521107.1
TG
thyroglobulin
chr10_-_14880002 0.67 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr9_+_34957477 0.67 ENST00000544237.1
KIAA1045
KIAA1045
chr17_-_1553346 0.67 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr15_+_54901540 0.66 ENST00000539562.2
UNC13C
unc-13 homolog C (C. elegans)
chr6_-_39290316 0.66 ENST00000425054.2
ENST00000373227.4
ENST00000373229.5
ENST00000437525.2
KCNK16
potassium channel, subfamily K, member 16
chr17_-_79359154 0.65 ENST00000572077.1
RP11-1055B8.3
RP11-1055B8.3
chr14_+_22963806 0.65 ENST00000390493.1
TRAJ44
T cell receptor alpha joining 44
chr5_-_107703556 0.65 ENST00000496714.1
FBXL17
F-box and leucine-rich repeat protein 17
chr6_-_34664612 0.64 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr3_+_9745510 0.64 ENST00000383831.3
CPNE9
copine family member IX
chr3_+_159570722 0.64 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr17_-_9923302 0.63 ENST00000579158.1
ENST00000542249.1
GAS7
growth arrest-specific 7
chr6_-_76072719 0.63 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr14_-_61190754 0.63 ENST00000216513.4
SIX4
SIX homeobox 4
chr10_+_11207438 0.62 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chr9_+_113431059 0.62 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr2_-_207024233 0.62 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr8_-_131028869 0.60 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chrX_-_150067069 0.60 ENST00000466436.1
CD99L2
CD99 molecule-like 2
chr15_+_78441663 0.60 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr12_-_8088773 0.60 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr22_-_24110063 0.60 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr4_-_139163491 0.58 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr10_+_11207485 0.57 ENST00000537122.1
CELF2
CUGBP, Elav-like family member 2
chr14_-_21492251 0.56 ENST00000554398.1
NDRG2
NDRG family member 2
chr12_-_16761007 0.55 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_44336754 0.54 ENST00000538168.1
ENST00000536490.1
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr18_-_12377001 0.54 ENST00000590811.1
AFG3L2
AFG3-like AAA ATPase 2
chr8_-_145018905 0.54 ENST00000398774.2
PLEC
plectin
chr10_-_75634219 0.54 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr22_+_18121356 0.53 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr14_+_75761099 0.53 ENST00000561000.1
ENST00000558575.1
RP11-293M10.5
RP11-293M10.5
chr17_+_42836521 0.52 ENST00000535346.1
ADAM11
ADAM metallopeptidase domain 11
chr9_+_129567282 0.52 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
ZBTB43
zinc finger and BTB domain containing 43
chr10_+_81107271 0.51 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr15_-_43882140 0.50 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr14_-_104387888 0.50 ENST00000286953.3
C14orf2
chromosome 14 open reading frame 2
chr3_-_15540055 0.50 ENST00000605797.1
ENST00000435459.2
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr12_-_95397442 0.49 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr22_+_18121562 0.49 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr16_-_4466565 0.49 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr7_-_81399744 0.49 ENST00000421558.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr17_-_36760865 0.48 ENST00000584266.1
SRCIN1
SRC kinase signaling inhibitor 1
chr5_-_131347583 0.48 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr6_+_139456226 0.47 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr15_-_88247083 0.47 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chr12_-_6715808 0.46 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr12_-_15865844 0.46 ENST00000543612.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr18_-_12377283 0.46 ENST00000269143.3
AFG3L2
AFG3-like AAA ATPase 2
chr3_+_9745487 0.46 ENST00000383832.3
CPNE9
copine family member IX
chr17_-_2615031 0.45 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr16_+_11038403 0.45 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr17_-_10276319 0.45 ENST00000252172.4
ENST00000418404.3
MYH13
myosin, heavy chain 13, skeletal muscle
chr8_-_131028641 0.45 ENST00000523509.1
FAM49B
family with sequence similarity 49, member B
chr6_+_36683256 0.44 ENST00000229824.8
RAB44
RAB44, member RAS oncogene family
chr9_-_136344237 0.44 ENST00000432868.1
ENST00000371899.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr1_+_36024107 0.43 ENST00000437806.1
NCDN
neurochondrin
chr18_+_13382553 0.43 ENST00000586222.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr22_+_23213658 0.43 ENST00000390318.2
IGLV4-3
immunoglobulin lambda variable 4-3
chr2_+_191334212 0.42 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr22_-_32341336 0.42 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr2_+_133874577 0.42 ENST00000596384.1
AC011755.1
HCG2006742; Protein LOC100996685
chr22_+_30163340 0.42 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr22_+_50354104 0.42 ENST00000360612.4
PIM3
pim-3 oncogene
chr12_-_81992111 0.41 ENST00000443686.3
ENST00000407050.4
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chrX_+_72223352 0.41 ENST00000373521.2
ENST00000538388.1
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr15_-_75017711 0.40 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr3_-_197024965 0.40 ENST00000392382.2
DLG1
discs, large homolog 1 (Drosophila)
chr11_-_9336117 0.39 ENST00000527813.1
ENST00000533723.1
TMEM41B
transmembrane protein 41B
chr10_+_14880364 0.39 ENST00000441647.1
HSPA14
heat shock 70kDa protein 14
chr12_-_8088871 0.39 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr11_+_34938119 0.39 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr3_-_197025447 0.39 ENST00000346964.2
ENST00000357674.4
ENST00000314062.3
ENST00000448528.2
ENST00000419553.1
DLG1
discs, large homolog 1 (Drosophila)
chr9_-_136344197 0.38 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr1_+_32084641 0.38 ENST00000373706.5
HCRTR1
hypocretin (orexin) receptor 1
chr1_+_206858232 0.37 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr1_+_174417095 0.37 ENST00000367685.2
GPR52
G protein-coupled receptor 52
chr9_+_112852477 0.37 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr1_-_234667504 0.36 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chrX_-_150067272 0.36 ENST00000355149.3
ENST00000437787.2
CD99L2
CD99 molecule-like 2
chrX_+_153639856 0.35 ENST00000426834.1
ENST00000369790.4
ENST00000454722.1
ENST00000350743.4
ENST00000299328.5
ENST00000351413.4
TAZ
tafazzin
chr7_+_129007964 0.35 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr17_+_45973516 0.35 ENST00000376741.4
SP2
Sp2 transcription factor
chr17_-_56350797 0.35 ENST00000577220.1
MPO
myeloperoxidase
chr15_+_43985084 0.35 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr20_+_47538357 0.34 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_-_78052923 0.34 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr1_-_36023251 0.34 ENST00000426982.2
KIAA0319L
KIAA0319-like
chr12_-_22487588 0.34 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr6_+_107077471 0.33 ENST00000369044.1
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr5_+_218356 0.33 ENST00000264932.6
ENST00000504309.1
ENST00000510361.1
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr3_-_10028366 0.33 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr1_+_36690011 0.33 ENST00000354618.5
ENST00000469141.2
ENST00000478853.1
THRAP3
thyroid hormone receptor associated protein 3
chr2_-_26467557 0.33 ENST00000380649.3
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr15_+_43885252 0.32 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43885799 0.32 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr15_-_42565023 0.32 ENST00000566474.1
TMEM87A
transmembrane protein 87A
chr7_-_105029812 0.32 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr8_+_145149930 0.32 ENST00000318911.4
CYC1
cytochrome c-1
chr8_-_93115508 0.32 ENST00000518832.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_+_54606145 0.31 ENST00000485876.1
ENST00000391762.1
ENST00000471292.1
ENST00000391763.3
ENST00000391764.3
ENST00000303553.5
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr2_+_11817713 0.31 ENST00000449576.2
LPIN1
lipin 1
chr14_+_22320634 0.31 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr14_-_104387831 0.31 ENST00000557040.1
ENST00000414262.2
ENST00000555030.1
ENST00000554713.1
ENST00000553430.1
C14orf2
chromosome 14 open reading frame 2
chr1_-_8877692 0.31 ENST00000400908.2
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr14_-_21492113 0.31 ENST00000554094.1
NDRG2
NDRG family member 2
chr2_-_26467465 0.31 ENST00000457468.2
HADHA
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
chr19_+_38880695 0.30 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr2_+_162016827 0.30 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr5_-_133340326 0.30 ENST00000425992.1
ENST00000395044.3
ENST00000395047.2
VDAC1
voltage-dependent anion channel 1
chrX_-_150067173 0.30 ENST00000370377.3
ENST00000320893.6
CD99L2
CD99 molecule-like 2
chr20_-_21086975 0.29 ENST00000420705.1
ENST00000593272.1
LINC00237
long intergenic non-protein coding RNA 237
chr5_-_131347501 0.29 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr3_-_46000146 0.29 ENST00000438446.1
FYCO1
FYVE and coiled-coil domain containing 1
chr8_-_100905850 0.28 ENST00000520271.1
ENST00000522940.1
ENST00000523016.1
ENST00000517682.2
ENST00000297564.2
COX6C
cytochrome c oxidase subunit VIc
chr22_+_40573921 0.28 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr1_+_206858328 0.27 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr10_+_81107216 0.27 ENST00000394579.3
ENST00000225174.3
PPIF
peptidylprolyl isomerase F
chr19_-_36054555 0.27 ENST00000262623.3
ATP4A
ATPase, H+/K+ exchanging, alpha polypeptide
chr9_-_138853156 0.26 ENST00000371756.3
UBAC1
UBA domain containing 1
chr1_+_16062820 0.26 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chrX_-_63005405 0.26 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
1.6 4.8 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.6 1.8 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.5 3.7 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.5 2.7 GO:0090131 mesenchyme migration(GO:0090131)
0.4 5.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 3.4 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.3 1.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.3 1.9 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.3 0.8 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 2.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.7 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 1.8 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 1.5 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.2 0.8 GO:1901143 insulin catabolic process(GO:1901143)
0.2 1.8 GO:0001878 response to yeast(GO:0001878)
0.2 1.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 1.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 4.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 1.8 GO:0070560 protein secretion by platelet(GO:0070560)
0.2 2.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.4 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 1.6 GO:0071313 cellular response to caffeine(GO:0071313) Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.1 0.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.2 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.0 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 2.0 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 1.0 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.8 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 5.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.7 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.0 3.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.9 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.6 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.6 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.7 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1903275 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.2 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 1.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.5 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.1 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.7 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.3 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.4 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 2.1 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.3 2.1 GO:0005927 muscle tendon junction(GO:0005927)
0.3 1.0 GO:0098855 HCN channel complex(GO:0098855)
0.3 1.0 GO:0005745 m-AAA complex(GO:0005745)
0.3 0.3 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.3 4.8 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.2 2.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.8 GO:0097486 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.1 0.3 GO:0032279 axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 3.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 1.4 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.0 7.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.7 3.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 0.8 GO:0031626 beta-endorphin binding(GO:0031626)
0.3 1.9 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 1.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 4.8 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.6 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0004040 amidase activity(GO:0004040)
0.1 0.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 1.8 GO:0031433 telethonin binding(GO:0031433)
0.1 0.6 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 1.0 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0016499 orexin receptor activity(GO:0016499)
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.8 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.1 2.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.3 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.9 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.5 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 4.4 GO:0043531 ADP binding(GO:0043531)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 1.0 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 3.1 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 2.0 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 5.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 3.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.3 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 3.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation