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Illumina Body Map 2, young vs old

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Results for PAX3

Z-value: 0.11

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Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
PAX3
ENSG00000135903.14 paired box 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg19_v2_chr2_-_223163465_2231637300.318.5e-02Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_44258360 7.10 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr22_-_44258280 5.75 ENST00000540422.1
SULT4A1
sulfotransferase family 4A, member 1
chr11_+_65122216 3.55 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr3_+_14716606 3.40 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chrX_+_70364667 3.22 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chrX_+_37850026 3.19 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr2_+_217735493 3.13 ENST00000456163.1
AC007557.1
HCG1816075; Uncharacterized protein
chr15_+_39765435 3.00 ENST00000560552.1
RP11-624L4.2
RP11-624L4.2
chr22_+_42372764 2.96 ENST00000396426.3
ENST00000406029.1
SEPT3
septin 3
chr7_+_142031986 2.89 ENST00000547918.2
TRBV7-1
T cell receptor beta variable 7-1 (non-functional)
chrX_-_70326455 2.80 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr4_-_168155577 2.76 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_154127518 2.74 ENST00000368559.3
ENST00000271854.3
NUP210L
nucleoporin 210kDa-like
chr1_+_50513686 2.67 ENST00000448907.2
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr16_-_52640834 2.64 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr2_-_217724767 2.61 ENST00000236979.2
TNP1
transition protein 1 (during histone to protamine replacement)
chr14_+_22217447 2.52 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr4_-_168155730 2.39 ENST00000502330.1
ENST00000357154.3
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_168155700 2.35 ENST00000357545.4
ENST00000512648.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_+_38226827 2.30 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
TMCO5A
transmembrane and coiled-coil domains 5A
chr14_-_21058982 2.26 ENST00000556526.1
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr7_-_142659388 2.25 ENST00000476829.1
ENST00000467543.1
KEL
Kell blood group, metallo-endopeptidase
chr11_-_62477313 2.22 ENST00000464544.1
ENST00000530009.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_73358594 2.22 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrY_+_20708557 2.18 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr2_-_11810284 2.17 ENST00000306928.5
NTSR2
neurotensin receptor 2
chrY_-_20935572 2.09 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr11_+_73358690 2.07 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr12_-_10562356 2.04 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr4_-_168155417 2.04 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_48116540 2.00 ENST00000506073.1
TXK
TXK tyrosine kinase
chr5_-_157079428 1.99 ENST00000265007.6
SOX30
SRY (sex determining region Y)-box 30
chr12_-_58131931 1.99 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr15_+_51973680 1.95 ENST00000542355.2
SCG3
secretogranin III
chrX_+_30265256 1.94 ENST00000397548.2
MAGEB1
melanoma antigen family B, 1
chr22_+_18593507 1.92 ENST00000330423.3
TUBA8
tubulin, alpha 8
chr16_+_23847339 1.90 ENST00000303531.7
PRKCB
protein kinase C, beta
chr5_+_171621176 1.85 ENST00000398186.4
EFCAB9
EF-hand calcium binding domain 9
chr15_+_51973708 1.73 ENST00000558709.1
SCG3
secretogranin III
chr12_-_75603643 1.68 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr11_+_66059339 1.68 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr14_+_52313833 1.66 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr10_-_104178857 1.63 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr11_-_19082216 1.61 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr9_+_33795533 1.59 ENST00000379405.3
PRSS3
protease, serine, 3
chr5_+_127039075 1.59 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr3_-_51813009 1.56 ENST00000398780.3
IQCF6
IQ motif containing F6
chr5_+_7654057 1.56 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr15_+_51973550 1.52 ENST00000220478.3
SCG3
secretogranin III
chr7_-_142232071 1.52 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr14_+_22675388 1.51 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chr3_-_110612323 1.50 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr2_+_242811874 1.49 ENST00000343216.3
CXXC11
CXXC finger protein 11
chr11_+_112038088 1.43 ENST00000530752.1
ENST00000280358.4
TEX12
testis expressed 12
chr19_-_19626351 1.42 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr5_+_147648393 1.37 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr19_-_35719609 1.34 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr10_-_126432821 1.32 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr20_-_17511962 1.29 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr1_-_7913089 1.29 ENST00000361696.5
UTS2
urotensin 2
chr6_-_10435032 1.27 ENST00000491317.1
ENST00000496285.1
ENST00000479822.1
ENST00000487130.1
LINC00518
long intergenic non-protein coding RNA 518
chr7_-_19813192 1.26 ENST00000422233.1
ENST00000433641.1
TMEM196
transmembrane protein 196
chr18_+_23806437 1.26 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr1_+_209545365 1.25 ENST00000447257.1
RP11-372M18.2
RP11-372M18.2
chr11_+_65851443 1.25 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr19_-_52005009 1.22 ENST00000291707.3
SIGLEC12
sialic acid binding Ig-like lectin 12 (gene/pseudogene)
chr10_+_134150835 1.22 ENST00000432555.2
LRRC27
leucine rich repeat containing 27
chr14_+_22964877 1.18 ENST00000390494.1
TRAJ43
T cell receptor alpha joining 43
chr18_+_23806382 1.16 ENST00000400466.2
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr7_-_142162390 1.13 ENST00000390371.3
TRBV6-6
T cell receptor beta variable 6-6
chr14_-_69658127 1.12 ENST00000556182.1
RP11-363J20.1
RP11-363J20.1
chr17_-_60883993 1.12 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr6_-_109804412 1.09 ENST00000230122.3
ZBTB24
zinc finger and BTB domain containing 24
chr1_+_84629976 1.09 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_37407172 1.07 ENST00000391711.3
ZNF829
zinc finger protein 829
chr2_-_96812751 1.06 ENST00000449242.1
AC012307.2
AC012307.2
chr19_-_48048518 1.06 ENST00000595558.1
ENST00000263351.5
ZNF541
zinc finger protein 541
chr7_-_107883678 1.06 ENST00000417701.1
NRCAM
neuronal cell adhesion molecule
chr12_-_69080590 1.04 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr7_-_142198049 1.03 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr4_-_104119528 1.01 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
CENPE
centromere protein E, 312kDa
chr12_+_7060414 1.00 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr10_+_124739911 0.99 ENST00000405485.1
PSTK
phosphoseryl-tRNA kinase
chr1_-_205180664 0.98 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
DSTYK
dual serine/threonine and tyrosine protein kinase
chr9_-_114521783 0.97 ENST00000394779.3
ENST00000394777.4
C9orf84
chromosome 9 open reading frame 84
chr7_+_99816859 0.97 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr1_-_145715565 0.97 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr12_+_8309630 0.96 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr17_-_39538550 0.96 ENST00000394001.1
KRT34
keratin 34
chr10_+_129785574 0.94 ENST00000430713.2
ENST00000471218.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_+_84630053 0.92 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_108786689 0.91 ENST00000415641.3
NBPF4
neuroblastoma breakpoint family, member 4
chr1_-_243349684 0.91 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr2_+_240323439 0.91 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chr10_+_118305435 0.91 ENST00000369221.2
PNLIP
pancreatic lipase
chr19_+_31658405 0.89 ENST00000589511.1
CTC-439O9.3
CTC-439O9.3
chr6_+_36683256 0.88 ENST00000229824.8
RAB44
RAB44, member RAS oncogene family
chr7_-_151330218 0.87 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr12_+_7060508 0.85 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_-_88200641 0.84 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr8_+_117950422 0.83 ENST00000378279.3
AARD
alanine and arginine rich domain containing protein
chr19_+_32836499 0.83 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr4_+_14113592 0.83 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr5_-_177180297 0.83 ENST00000504518.1
FAM153A
family with sequence similarity 153, member A
chr1_+_247670360 0.82 ENST00000527084.1
ENST00000527541.1
ENST00000366490.3
GCSAML
germinal center-associated, signaling and motility-like
chr17_-_59668550 0.81 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr22_+_27068704 0.80 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chrX_+_114423963 0.79 ENST00000424776.3
RBMXL3
RNA binding motif protein, X-linked-like 3
chr6_+_140175987 0.79 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr11_+_33563821 0.79 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr10_+_129785536 0.78 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chrX_-_15872914 0.77 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_152214098 0.76 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr17_+_35732916 0.76 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr15_-_43622736 0.75 ENST00000544735.1
ENST00000567039.1
ENST00000305641.5
LCMT2
leucine carboxyl methyltransferase 2
chr5_-_35938674 0.75 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr17_+_35732955 0.75 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chrX_-_13835461 0.74 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr13_+_96085847 0.74 ENST00000376873.3
CLDN10
claudin 10
chr2_-_25194476 0.73 ENST00000534855.1
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr13_-_81801115 0.71 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr4_-_87278857 0.71 ENST00000509464.1
ENST00000511167.1
MAPK10
mitogen-activated protein kinase 10
chr9_+_104161123 0.70 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chr5_+_177457525 0.68 ENST00000511856.1
ENST00000511189.1
FAM153C
family with sequence similarity 153, member C
chr6_+_10634158 0.66 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr3_-_119379719 0.66 ENST00000493094.1
POPDC2
popeye domain containing 2
chr20_-_23807358 0.65 ENST00000304725.2
CST2
cystatin SA
chr12_+_9142131 0.65 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr10_-_75226166 0.65 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr4_-_87279520 0.64 ENST00000506773.1
MAPK10
mitogen-activated protein kinase 10
chr7_+_142457315 0.63 ENST00000486171.1
ENST00000311737.7
PRSS1
protease, serine, 1 (trypsin 1)
chr12_+_7060432 0.62 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_+_66624527 0.61 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr14_+_19553365 0.61 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr1_+_99729813 0.61 ENST00000457765.1
LPPR4
Lipid phosphate phosphatase-related protein type 4
chr8_+_107670064 0.61 ENST00000312046.6
OXR1
oxidation resistance 1
chr6_+_28493753 0.60 ENST00000469384.1
GPX5
glutathione peroxidase 5 (epididymal androgen-related protein)
chr15_-_52861157 0.59 ENST00000564163.1
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr4_-_170924888 0.58 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr1_-_247887345 0.58 ENST00000366485.1
OR14A2
olfactory receptor, family 14, subfamily A, member 2
chr15_-_80263506 0.57 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr5_-_67829357 0.57 ENST00000515199.1
CTC-537E7.2
CTC-537E7.2
chr12_+_10460549 0.57 ENST00000543420.1
ENST00000543777.1
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr9_-_21239978 0.56 ENST00000380222.2
IFNA14
interferon, alpha 14
chr5_-_180688105 0.55 ENST00000327767.4
TRIM52
tripartite motif containing 52
chr8_-_121825088 0.54 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_-_41903161 0.54 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr19_-_38085633 0.54 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr10_-_50143242 0.53 ENST00000298124.3
LRRC18
leucine rich repeat containing 18
chr22_+_27068766 0.53 ENST00000435162.1
ENST00000437071.1
ENST00000440816.1
ENST00000421253.1
CTA-211A9.5
CTA-211A9.5
chr2_-_128051670 0.52 ENST00000493187.2
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr6_+_14117872 0.51 ENST00000379153.3
CD83
CD83 molecule
chr12_+_652294 0.51 ENST00000322843.3
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr8_-_81083618 0.50 ENST00000520795.1
TPD52
tumor protein D52
chr19_+_38085731 0.49 ENST00000589117.1
ZNF540
zinc finger protein 540
chr4_+_105828492 0.47 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr12_-_53594227 0.47 ENST00000550743.2
ITGB7
integrin, beta 7
chr19_+_2841433 0.47 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
ZNF555
zinc finger protein 555
chrX_-_13835398 0.45 ENST00000475307.1
GPM6B
glycoprotein M6B
chr13_+_76445187 0.45 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr5_+_49961727 0.44 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr19_+_38085768 0.44 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr7_-_148580563 0.43 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_11036272 0.43 ENST00000520253.1
C1orf127
chromosome 1 open reading frame 127
chr9_-_35650900 0.42 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr10_+_91087651 0.42 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_31391276 0.42 ENST00000452803.1
DCDC1
doublecortin domain containing 1
chr6_+_10633993 0.41 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr6_-_32908765 0.41 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr14_+_45464658 0.41 ENST00000555874.1
FAM179B
family with sequence similarity 179, member B
chr12_+_10460417 0.41 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chrX_-_48931648 0.40 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr1_+_158323486 0.40 ENST00000444681.2
ENST00000368167.3
CD1E
CD1e molecule
chr2_-_128051708 0.39 ENST00000285398.2
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr2_-_44588893 0.38 ENST00000409272.1
ENST00000410081.1
ENST00000541738.1
PREPL
prolyl endopeptidase-like
chr2_-_68479614 0.37 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr6_+_1080164 0.37 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr11_-_104972158 0.36 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr3_-_55001115 0.34 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr2_-_219524193 0.33 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chrX_+_68725084 0.33 ENST00000252338.4
FAM155B
family with sequence similarity 155, member B
chr17_-_3461092 0.33 ENST00000301365.4
ENST00000572519.1
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chrX_-_118699325 0.32 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
CXorf56
chromosome X open reading frame 56
chr19_-_57183114 0.32 ENST00000537055.2
ENST00000601659.1
ZNF835
zinc finger protein 835
chr6_-_9939552 0.32 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr9_+_100395891 0.31 ENST00000375147.3
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr5_-_179498703 0.30 ENST00000522208.2
RNF130
ring finger protein 130
chr1_-_183538319 0.29 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr1_+_248651885 0.29 ENST00000366473.2
OR2T5
olfactory receptor, family 2, subfamily T, member 5
chr16_-_71523179 0.28 ENST00000564230.1
ENST00000565637.1
ZNF19
zinc finger protein 19
chr3_+_112709804 0.28 ENST00000383677.3
GTPBP8
GTP-binding protein 8 (putative)
chr1_+_247670415 0.28 ENST00000366491.2
ENST00000366489.1
ENST00000526896.1
GCSAML
germinal center-associated, signaling and motility-like
chr19_+_55105085 0.25 ENST00000251372.3
ENST00000453777.1
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chrX_+_153770421 0.25 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr7_+_129015671 0.25 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_-_52344416 0.25 ENST00000544028.1
NRD1
nardilysin (N-arginine dibasic convertase)
chr10_+_90521163 0.25 ENST00000404459.1
LIPN
lipase, family member N
chr14_+_69658480 0.24 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
EXD2
exonuclease 3'-5' domain containing 2
chr6_+_127588020 0.24 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146
ring finger protein 146
chr6_-_32908792 0.24 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.6 2.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.5 1.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.4 1.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 2.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.4 9.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 2.6 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.4 1.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.3 2.0 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 12.8 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.2 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 1.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.7 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.2 2.0 GO:0097338 response to clozapine(GO:0097338)
0.2 1.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 1.0 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 1.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 2.7 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.5 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 1.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 1.3 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 2.2 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.0 1.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 4.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.9 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 2.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.9 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 3.9 GO:0006968 cellular defense response(GO:0006968)
0.0 1.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 1.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.6 GO:0030431 sleep(GO:0030431)
0.0 1.3 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.3 GO:1905216 positive regulation of RNA binding(GO:1905216)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 1.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.0 GO:0040017 positive regulation of cell migration(GO:0030335) positive regulation of locomotion(GO:0040017) positive regulation of cellular component movement(GO:0051272) positive regulation of cell motility(GO:2000147)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 2.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.4 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.0 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.9 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.1 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.1 GO:0043194 axon initial segment(GO:0043194)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.7 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 2.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 4.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.4 12.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 9.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.0 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.2 0.9 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 2.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 3.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 4.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.9 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.6 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.5 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 2.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 2.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 9.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.5 PID EPO PATHWAY EPO signaling pathway
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 1.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 3.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins