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Illumina Body Map 2, young vs old

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Results for PAX4

Z-value: 0.38

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255982_127255982-0.096.2e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_26644441 6.90 ENST00000374213.2
CD52 molecule
chr1_-_153348067 5.65 ENST00000368737.3
S100 calcium binding protein A12
chr4_-_84030996 5.28 ENST00000411416.2
placenta-specific 8
chr12_-_45269769 4.06 ENST00000548826.1
NEL-like 2 (chicken)
chr5_+_147258266 4.03 ENST00000296694.4
secretoglobin, family 3A, member 2
chr12_-_45269430 3.95 ENST00000395487.2
NEL-like 2 (chicken)
chr1_-_25291475 3.81 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr6_+_31553901 3.75 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr6_-_25042390 3.70 ENST00000606385.1
RP11-367G6.3
chr12_-_45269251 3.67 ENST00000553120.1
NEL-like 2 (chicken)
chr6_+_31553978 3.61 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr2_-_136875712 3.58 ENST00000241393.3
chemokine (C-X-C motif) receptor 4
chr19_+_55105085 3.58 ENST00000251372.3
ENST00000453777.1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr7_+_26331541 3.57 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr6_-_25042231 3.50 ENST00000510784.2
family with sequence similarity 65, member B
chr6_+_31554612 3.38 ENST00000211921.7
leukocyte specific transcript 1
chr6_+_31554456 3.38 ENST00000339530.4
leukocyte specific transcript 1
chr8_-_126963487 3.34 ENST00000518964.1
long intergenic non-protein coding RNA 861
chr22_-_17700260 3.32 ENST00000399837.2
ENST00000543038.1
cat eye syndrome chromosome region, candidate 1
chr1_+_101702417 3.31 ENST00000305352.6
sphingosine-1-phosphate receptor 1
chr7_+_26331678 3.26 ENST00000446848.2
sorting nexin 10
chr2_-_136873735 3.23 ENST00000409817.1
chemokine (C-X-C motif) receptor 4
chr7_+_80267949 3.16 ENST00000482059.2
CD36 molecule (thrombospondin receptor)
chr7_+_80267973 3.13 ENST00000394788.3
ENST00000447544.2
CD36 molecule (thrombospondin receptor)
chr5_+_118668846 3.12 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chr2_-_87088995 3.11 ENST00000393759.2
ENST00000349455.3
ENST00000331469.2
ENST00000431506.2
ENST00000393761.2
ENST00000390655.6
CD8b molecule
chr22_+_23229960 3.10 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
immunoglobulin lambda-like polypeptide 5
chr19_-_54784937 3.09 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr9_-_20622478 3.06 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_31554636 2.97 ENST00000433492.1
leukocyte specific transcript 1
chr1_-_151032040 2.88 ENST00000540998.1
ENST00000357235.5
CDC42 small effector 1
chr6_+_32407619 2.85 ENST00000395388.2
ENST00000374982.5
major histocompatibility complex, class II, DR alpha
chr11_-_124622134 2.78 ENST00000326621.5
V-set and immunoglobulin domain containing 2
chr1_+_21880560 2.72 ENST00000425315.2
alkaline phosphatase, liver/bone/kidney
chr19_+_55141861 2.64 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chrX_-_49121165 2.63 ENST00000376207.4
ENST00000376199.2
forkhead box P3
chr8_-_21771182 2.58 ENST00000523932.1
ENST00000544659.1
docking protein 2, 56kDa
chr11_-_58980342 2.56 ENST00000361050.3
macrophage expressed 1
chr16_-_28621353 2.43 ENST00000567512.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_10959043 2.41 ENST00000397820.4
chromosome 19 open reading frame 38
chr3_+_27754397 2.38 ENST00000606069.1
RP11-222K16.2
chr17_+_43299241 2.38 ENST00000328118.3
formin-like 1
chr19_+_55141948 2.38 ENST00000396332.4
ENST00000427581.2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr16_-_28621298 2.32 ENST00000566189.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr8_-_21771214 2.32 ENST00000276420.4
docking protein 2, 56kDa
chr17_+_7253667 2.31 ENST00000570504.1
ENST00000574499.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_-_23510086 2.28 ENST00000258729.3
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_7253635 2.28 ENST00000571471.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_-_101410762 2.26 ENST00000543160.1
ENST00000333643.3
brain expressed, X-linked 5
chr12_-_121477039 2.26 ENST00000257570.5
2'-5'-oligoadenylate synthetase-like
chr20_-_52210368 2.22 ENST00000371471.2
zinc finger protein 217
chr8_-_21771173 2.19 ENST00000518197.1
docking protein 2, 56kDa
chr16_-_28621312 2.19 ENST00000314752.7
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_131623982 2.18 ENST00000370844.1
muscleblind-like splicing regulator 3
chr11_-_124622083 2.03 ENST00000403470.1
V-set and immunoglobulin domain containing 2
chrX_-_131623874 2.00 ENST00000436215.1
muscleblind-like splicing regulator 3
chr18_-_3013307 1.99 ENST00000584294.1
lipin 2
chr12_-_121476959 1.97 ENST00000339275.5
2'-5'-oligoadenylate synthetase-like
chr16_+_50730910 1.97 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr2_+_185463093 1.94 ENST00000302277.6
zinc finger protein 804A
chr19_-_36391434 1.91 ENST00000396901.1
ENST00000585925.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr14_-_50053081 1.90 ENST00000396020.3
ENST00000245458.6
ribosomal protein S29
chr9_-_20621834 1.89 ENST00000429426.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr13_+_28712614 1.88 ENST00000380958.3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_44465475 1.80 ENST00000416124.1
long intergenic non-protein coding RNA 694
chr6_+_32605134 1.75 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
major histocompatibility complex, class II, DQ alpha 1
chr19_-_55836697 1.73 ENST00000438693.1
ENST00000591570.1
transmembrane protein 150B
chr6_+_15246501 1.67 ENST00000341776.2
jumonji, AT rich interactive domain 2
chr1_+_21877753 1.66 ENST00000374832.1
alkaline phosphatase, liver/bone/kidney
chr11_+_1874200 1.64 ENST00000311604.3
lymphocyte-specific protein 1
chr19_-_55836669 1.61 ENST00000326652.4
transmembrane protein 150B
chr8_-_101963482 1.59 ENST00000419477.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_71632894 1.59 ENST00000493089.1
forkhead box P1
chr4_-_141074123 1.57 ENST00000502696.1
mastermind-like 3 (Drosophila)
chr15_-_40401062 1.51 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr16_-_28608424 1.51 ENST00000335715.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr22_-_31688431 1.50 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr2_+_102972363 1.45 ENST00000409599.1
interleukin 18 receptor 1
chr6_+_32605195 1.45 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr17_+_7254184 1.44 ENST00000575415.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr22_-_31688381 1.43 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr9_+_134103496 1.42 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
nucleoporin 214kDa
chr8_-_116680833 1.41 ENST00000220888.5
trichorhinophalangeal syndrome I
chr7_-_139763521 1.39 ENST00000263549.3
poly (ADP-ribose) polymerase family, member 12
chr1_+_12123414 1.36 ENST00000263932.2
tumor necrosis factor receptor superfamily, member 8
chr6_+_133135580 1.35 ENST00000230050.3
ribosomal protein S12
chr7_+_26191809 1.34 ENST00000056233.3
nuclear factor, erythroid 2-like 3
chr6_-_90062543 1.34 ENST00000435041.2
ubiquitin-conjugating enzyme E2, J1
chr21_+_26934165 1.32 ENST00000456917.1
MIR155 host gene (non-protein coding)
chr10_+_114135004 1.32 ENST00000393081.1
acyl-CoA synthetase long-chain family member 5
chr8_-_623547 1.30 ENST00000522893.1
glutamate-rich 1
chr8_-_101963677 1.29 ENST00000395956.3
ENST00000395953.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_+_69064566 1.28 ENST00000403018.2
autism susceptibility candidate 2
chr17_+_72322346 1.27 ENST00000551294.1
ENST00000389916.4
kinesin family member 19
chr1_+_155146318 1.26 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
tripartite motif containing 46
chr3_+_46283863 1.25 ENST00000545097.1
ENST00000541018.1
chemokine (C-C motif) receptor 3
chr1_+_161190160 1.25 ENST00000594609.1
Uncharacterized protein
chr7_-_137686791 1.24 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr16_+_69958887 1.24 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr11_+_134144139 1.23 ENST00000389887.5
galactosidase, beta 1-like 3
chr4_-_113207048 1.22 ENST00000361717.3
TRAF-interacting protein with forkhead-associated domain
chr19_-_10420459 1.19 ENST00000403352.1
ENST00000403903.3
zinc finger, GATA-like protein 1
chr18_-_53255379 1.17 ENST00000565908.2
transcription factor 4
chr11_-_93276582 1.17 ENST00000298966.2
single-pass membrane protein with coiled-coil domains 4
chr7_-_38313235 1.13 ENST00000390338.2
T cell receptor gamma joining P
chr4_+_47487285 1.13 ENST00000273859.3
ENST00000504445.1
ATPase, class V, type 10D
chr1_+_12123463 1.11 ENST00000417814.2
tumor necrosis factor receptor superfamily, member 8
chr15_-_60690932 1.08 ENST00000559818.1
annexin A2
chr12_+_121570631 1.07 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_-_37488834 1.05 ENST00000310758.4
engulfment and cell motility 1
chr2_+_99758161 1.05 ENST00000409684.1
Uncharacterized protein C2orf15
chr5_-_169407744 1.04 ENST00000377365.3
family with sequence similarity 196, member B
chr7_-_76955563 1.04 ENST00000441833.2
gamma-secretase activating protein
chr18_-_53089723 1.04 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr11_+_20385327 1.03 ENST00000451739.2
ENST00000532505.1
HIV-1 Tat interactive protein 2, 30kDa
chr7_+_69064300 1.03 ENST00000342771.4
autism susceptibility candidate 2
chr9_-_123676827 1.02 ENST00000546084.1
TNF receptor-associated factor 1
chr11_-_62368696 1.01 ENST00000527204.1
metastasis associated 1 family, member 2
chr1_-_85742773 1.01 ENST00000370580.1
B-cell CLL/lymphoma 10
chr7_-_37488777 1.00 ENST00000445322.1
ENST00000448602.1
engulfment and cell motility 1
chrX_-_131547596 1.00 ENST00000538204.1
ENST00000370849.3
muscleblind-like splicing regulator 3
chr18_-_60986613 0.99 ENST00000444484.1
B-cell CLL/lymphoma 2
chr11_+_46740730 0.99 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr4_-_40516560 0.98 ENST00000513473.1
RNA binding motif protein 47
chr22_-_39151463 0.98 ENST00000405510.1
ENST00000433561.1
Sad1 and UNC84 domain containing 2
chr11_-_65374430 0.98 ENST00000532507.1
mitogen-activated protein kinase kinase kinase 11
chr17_-_77005801 0.95 ENST00000392446.5
calcium activated nucleotidase 1
chr2_+_12857043 0.92 ENST00000381465.2
tribbles pseudokinase 2
chr6_-_32806483 0.92 ENST00000374899.4
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_152061537 0.92 ENST00000368806.1
trichohyalin-like 1
chr17_-_77005860 0.90 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
calcium activated nucleotidase 1
chr6_-_32095968 0.86 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr2_-_191878162 0.86 ENST00000540176.1
signal transducer and activator of transcription 1, 91kDa
chr3_+_46283916 0.86 ENST00000395940.2
chemokine (C-C motif) receptor 3
chr8_+_11666649 0.85 ENST00000528643.1
ENST00000525777.1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_72270380 0.83 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr1_-_228594490 0.81 ENST00000366699.3
ENST00000284551.6
tripartite motif containing 11
chr7_+_66386204 0.81 ENST00000341567.4
ENST00000607045.1
transmembrane protein 248
chrX_-_131547625 0.80 ENST00000394311.2
muscleblind-like splicing regulator 3
chr12_-_95945246 0.79 ENST00000258499.3
ubiquitin specific peptidase 44
chr21_-_33651324 0.79 ENST00000290130.3
MIS18 kinetochore protein A
chr6_-_130031358 0.79 ENST00000368149.2
Rho GTPase activating protein 18
chr3_+_107318157 0.78 ENST00000406780.1
bobby sox homolog (Drosophila)
chr18_+_72922710 0.78 ENST00000322038.5
teashirt zinc finger homeobox 1
chr11_+_20385231 0.77 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HIV-1 Tat interactive protein 2, 30kDa
chr12_-_109221160 0.77 ENST00000326470.5
slingshot protein phosphatase 1
chr16_-_28608364 0.77 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_21022818 0.76 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
chromosome 2 open reading frame 43
chr5_-_54988448 0.76 ENST00000503817.1
ENST00000512595.1
solute carrier family 38, member 9
chr16_-_84273304 0.76 ENST00000308251.4
ENST00000568181.1
potassium voltage-gated channel, subfamily G, member 4
chr17_-_77005813 0.76 ENST00000590370.1
ENST00000591625.1
calcium activated nucleotidase 1
chr3_-_197476560 0.75 ENST00000273582.5
KIAA0226
chr18_-_53255766 0.75 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
transcription factor 4
chr1_-_231376836 0.74 ENST00000451322.1
chromosome 1 open reading frame 131
chr9_-_4859260 0.74 ENST00000599351.1
HCG2011465; Uncharacterized protein
chr12_-_2986107 0.73 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr2_-_208489275 0.72 ENST00000272839.3
ENST00000426075.1
methyltransferase like 21A
chr11_-_67211263 0.72 ENST00000393893.1
coronin, actin binding protein, 1B
chr8_-_144660771 0.72 ENST00000449291.2
nicotinate phosphoribosyltransferase domain containing 1
chr20_+_277737 0.72 ENST00000382352.3
zinc finger, CCHC domain containing 3
chr14_-_50559361 0.71 ENST00000305273.1
chromosome 14 open reading frame 183
chr6_-_32806506 0.71 ENST00000374897.2
ENST00000452392.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr4_+_109571800 0.70 ENST00000512478.2
oligosaccharyltransferase complex subunit (non-catalytic)
chr12_-_99288536 0.70 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_231376867 0.70 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
chromosome 1 open reading frame 131
chr14_+_104394770 0.69 ENST00000409874.4
ENST00000339063.5
tudor domain containing 9
chr8_-_116681123 0.69 ENST00000519674.1
trichorhinophalangeal syndrome I
chr19_+_38779778 0.68 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4
chr3_-_142166904 0.68 ENST00000264951.4
5'-3' exoribonuclease 1
chr13_-_28194541 0.68 ENST00000316334.3
ligand of numb-protein X 2
chr1_-_151319283 0.68 ENST00000392746.3
regulatory factor X, 5 (influences HLA class II expression)
chr14_+_76072096 0.68 ENST00000555058.1
feline leukemia virus subgroup C cellular receptor family, member 2
chr14_+_78227105 0.67 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
chromosome 14 open reading frame 178
chr10_+_33271469 0.65 ENST00000414157.1
RP11-462L8.1
chr11_-_62474803 0.64 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_-_230787879 0.63 ENST00000435716.1
thyroid hormone receptor interactor 12
chr1_-_1624083 0.63 ENST00000378662.1
ENST00000234800.6
solute carrier family 35, member E2B
chr18_+_3448455 0.62 ENST00000549780.1
TGFB-induced factor homeobox 1
chr4_+_109571740 0.61 ENST00000361564.4
oligosaccharyltransferase complex subunit (non-catalytic)
chr19_-_51308175 0.60 ENST00000345523.4
chromosome 19 open reading frame 48
chr11_-_64545222 0.60 ENST00000433274.2
ENST00000432725.1
splicing factor 1
chr10_-_27703269 0.59 ENST00000438700.3
patched domain containing 3
chr3_+_119298523 0.58 ENST00000357003.3
ADP-ribosylarginine hydrolase
chr17_+_73089382 0.57 ENST00000538213.2
ENST00000584118.1
solute carrier family 16 (monocarboxylate transporter), member 5
chr10_-_14920599 0.56 ENST00000609399.1
RP11-398C13.6
chr5_+_150157444 0.55 ENST00000526627.1
small integral membrane protein 3
chr21_+_43934633 0.54 ENST00000398343.2
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr5_-_130500922 0.53 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
histidine triad nucleotide binding protein 1
chr20_-_44993012 0.53 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
solute carrier family 35 (GDP-fucose transporter), member C2
chr18_-_60987220 0.52 ENST00000398117.1
B-cell CLL/lymphoma 2
chr1_-_155145721 0.52 ENST00000295682.4
keratinocyte associated protein 2
chr18_+_29027696 0.51 ENST00000257189.4
desmoglein 3
chr10_-_70092671 0.51 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr4_+_95128996 0.50 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_176733897 0.48 ENST00000393658.2
glycoprotein M6A
chr18_-_5396271 0.47 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr12_-_57146095 0.46 ENST00000550770.1
ENST00000338193.6
primase, DNA, polypeptide 1 (49kDa)
chr15_-_34502278 0.46 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
katanin p80 subunit B-like 1
chr6_-_113754604 0.45 ENST00000421737.1
RP1-124C6.1
chr18_+_61254534 0.45 ENST00000269489.5
serpin peptidase inhibitor, clade B (ovalbumin), member 13

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0071529 cementum mineralization(GO:0071529)
1.3 5.0 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
1.1 3.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.9 2.6 GO:0032831 regulation of tolerance induction dependent upon immune response(GO:0002652) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.8 2.5 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.8 3.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.8 6.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 2.9 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 11.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.6 2.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.6 2.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.5 1.6 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.5 6.3 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 2.0 GO:0060585 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.5 2.0 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.4 1.2 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.4 1.1 GO:0043132 NAD transport(GO:0043132)
0.3 1.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.3 9.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.9 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.3 1.1 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 1.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 0.8 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.3 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 0.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.2 1.9 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 5.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 4.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.0 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 1.0 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 6.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 0.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 6.9 GO:0045730 respiratory burst(GO:0045730)
0.2 2.9 GO:0090168 Golgi reassembly(GO:0090168)
0.2 0.8 GO:0060023 soft palate development(GO:0060023)
0.1 17.4 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 6.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.4 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 0.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 3.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 5.8 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.7 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 5.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 2.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.7 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 1.2 GO:0051014 actin filament severing(GO:0051014)
0.0 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 7.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 3.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 3.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 2.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 1.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 2.6 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 2.3 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 2.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 4.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.5 1.9 GO:0031251 PAN complex(GO:0031251)
0.3 1.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 6.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.2 1.0 GO:0032449 CBM complex(GO:0032449)
0.1 4.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 4.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.7 GO:0071547 piP-body(GO:0071547)
0.1 5.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 3.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 5.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 5.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 5.7 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 4.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 5.8 GO:0005769 early endosome(GO:0005769)
0.0 5.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 11.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.3 5.0 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
1.0 2.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.8 3.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.6 6.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 4.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.5 8.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.5 2.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.4 6.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 4.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 1.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 5.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 3.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 7.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.9 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 2.6 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.0 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 5.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 2.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.5 GO:0003896 DNA primase activity(GO:0003896)
0.1 2.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 2.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 3.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.6 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 3.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 1.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 2.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 7.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 7.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 9.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 5.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 10.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 7.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 5.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 3.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 3.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors