Project

Illumina Body Map 2, young vs old

Navigation
Downloads

Results for PAX4

Z-value: 0.38

Motif logo

logo of

Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.10 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg19_v2_chr7_-_127255982_127255982-0.096.2e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_26644441 6.90 ENST00000374213.2
CD52
CD52 molecule
chr1_-_153348067 5.65 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr4_-_84030996 5.28 ENST00000411416.2
PLAC8
placenta-specific 8
chr12_-_45269769 4.06 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr5_+_147258266 4.03 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr12_-_45269430 3.95 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr1_-_25291475 3.81 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr6_+_31553901 3.75 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
LST1
leukocyte specific transcript 1
chr6_-_25042390 3.70 ENST00000606385.1
RP11-367G6.3
RP11-367G6.3
chr12_-_45269251 3.67 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr6_+_31553978 3.61 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr2_-_136875712 3.58 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr19_+_55105085 3.58 ENST00000251372.3
ENST00000453777.1
LILRA1
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
chr7_+_26331541 3.57 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr6_-_25042231 3.50 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr6_+_31554612 3.38 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr6_+_31554456 3.38 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr8_-_126963487 3.34 ENST00000518964.1
LINC00861
long intergenic non-protein coding RNA 861
chr22_-_17700260 3.32 ENST00000399837.2
ENST00000543038.1
CECR1
cat eye syndrome chromosome region, candidate 1
chr1_+_101702417 3.31 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr7_+_26331678 3.26 ENST00000446848.2
SNX10
sorting nexin 10
chr2_-_136873735 3.23 ENST00000409817.1
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_+_80267949 3.16 ENST00000482059.2
CD36
CD36 molecule (thrombospondin receptor)
chr7_+_80267973 3.13 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr5_+_118668846 3.12 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr2_-_87088995 3.11 ENST00000393759.2
ENST00000349455.3
ENST00000331469.2
ENST00000431506.2
ENST00000393761.2
ENST00000390655.6
CD8B
CD8b molecule
chr22_+_23229960 3.10 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr19_-_54784937 3.09 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr9_-_20622478 3.06 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_31554636 2.97 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr1_-_151032040 2.88 ENST00000540998.1
ENST00000357235.5
CDC42SE1
CDC42 small effector 1
chr6_+_32407619 2.85 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_-_124622134 2.78 ENST00000326621.5
VSIG2
V-set and immunoglobulin domain containing 2
chr1_+_21880560 2.72 ENST00000425315.2
ALPL
alkaline phosphatase, liver/bone/kidney
chr19_+_55141861 2.64 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chrX_-_49121165 2.63 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr8_-_21771182 2.58 ENST00000523932.1
ENST00000544659.1
DOK2
docking protein 2, 56kDa
chr11_-_58980342 2.56 ENST00000361050.3
MPEG1
macrophage expressed 1
chr16_-_28621353 2.43 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr19_+_10959043 2.41 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr3_+_27754397 2.38 ENST00000606069.1
RP11-222K16.2
RP11-222K16.2
chr17_+_43299241 2.38 ENST00000328118.3
FMNL1
formin-like 1
chr19_+_55141948 2.38 ENST00000396332.4
ENST00000427581.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr16_-_28621298 2.32 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr8_-_21771214 2.32 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr17_+_7253667 2.31 ENST00000570504.1
ENST00000574499.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr7_-_23510086 2.28 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_7253635 2.28 ENST00000571471.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_-_101410762 2.26 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr12_-_121477039 2.26 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr20_-_52210368 2.22 ENST00000371471.2
ZNF217
zinc finger protein 217
chr8_-_21771173 2.19 ENST00000518197.1
DOK2
docking protein 2, 56kDa
chr16_-_28621312 2.19 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_-_131623982 2.18 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr11_-_124622083 2.03 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chrX_-_131623874 2.00 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr18_-_3013307 1.99 ENST00000584294.1
LPIN2
lipin 2
chr12_-_121476959 1.97 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr16_+_50730910 1.97 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr2_+_185463093 1.94 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr19_-_36391434 1.91 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr14_-_50053081 1.90 ENST00000396020.3
ENST00000245458.6
RPS29
ribosomal protein S29
chr9_-_20621834 1.89 ENST00000429426.2
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr13_+_28712614 1.88 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_44465475 1.80 ENST00000416124.1
LINC00694
long intergenic non-protein coding RNA 694
chr6_+_32605134 1.75 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_-_55836697 1.73 ENST00000438693.1
ENST00000591570.1
TMEM150B
transmembrane protein 150B
chr6_+_15246501 1.67 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr1_+_21877753 1.66 ENST00000374832.1
ALPL
alkaline phosphatase, liver/bone/kidney
chr11_+_1874200 1.64 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr19_-_55836669 1.61 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chr8_-_101963482 1.59 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_71632894 1.59 ENST00000493089.1
FOXP1
forkhead box P1
chr4_-_141074123 1.57 ENST00000502696.1
MAML3
mastermind-like 3 (Drosophila)
chr15_-_40401062 1.51 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr16_-_28608424 1.51 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr22_-_31688431 1.50 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr2_+_102972363 1.45 ENST00000409599.1
IL18R1
interleukin 18 receptor 1
chr6_+_32605195 1.45 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr17_+_7254184 1.44 ENST00000575415.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr22_-_31688381 1.43 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr9_+_134103496 1.42 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr8_-_116680833 1.41 ENST00000220888.5
TRPS1
trichorhinophalangeal syndrome I
chr7_-_139763521 1.39 ENST00000263549.3
PARP12
poly (ADP-ribose) polymerase family, member 12
chr1_+_12123414 1.36 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr6_+_133135580 1.35 ENST00000230050.3
RPS12
ribosomal protein S12
chr7_+_26191809 1.34 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr6_-_90062543 1.34 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr21_+_26934165 1.32 ENST00000456917.1
MIR155HG
MIR155 host gene (non-protein coding)
chr10_+_114135004 1.32 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_-_623547 1.30 ENST00000522893.1
ERICH1
glutamate-rich 1
chr8_-_101963677 1.29 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_+_69064566 1.28 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr17_+_72322346 1.27 ENST00000551294.1
ENST00000389916.4
KIF19
kinesin family member 19
chr1_+_155146318 1.26 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr3_+_46283863 1.25 ENST00000545097.1
ENST00000541018.1
CCR3
chemokine (C-C motif) receptor 3
chr1_+_161190160 1.25 ENST00000594609.1
AL590714.1
Uncharacterized protein
chr7_-_137686791 1.24 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr16_+_69958887 1.24 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr11_+_134144139 1.23 ENST00000389887.5
GLB1L3
galactosidase, beta 1-like 3
chr4_-_113207048 1.22 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr19_-_10420459 1.19 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr18_-_53255379 1.17 ENST00000565908.2
TCF4
transcription factor 4
chr11_-_93276582 1.17 ENST00000298966.2
SMCO4
single-pass membrane protein with coiled-coil domains 4
chr7_-_38313235 1.13 ENST00000390338.2
TRGJP
T cell receptor gamma joining P
chr4_+_47487285 1.13 ENST00000273859.3
ENST00000504445.1
ATP10D
ATPase, class V, type 10D
chr1_+_12123463 1.11 ENST00000417814.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr15_-_60690932 1.08 ENST00000559818.1
ANXA2
annexin A2
chr12_+_121570631 1.07 ENST00000546057.1
ENST00000377162.2
ENST00000328963.5
ENST00000535250.1
ENST00000541446.1
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr7_-_37488834 1.05 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr2_+_99758161 1.05 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr5_-_169407744 1.04 ENST00000377365.3
FAM196B
family with sequence similarity 196, member B
chr7_-_76955563 1.04 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr18_-_53089723 1.04 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr11_+_20385327 1.03 ENST00000451739.2
ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr7_+_69064300 1.03 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr9_-_123676827 1.02 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr11_-_62368696 1.01 ENST00000527204.1
MTA2
metastasis associated 1 family, member 2
chr1_-_85742773 1.01 ENST00000370580.1
BCL10
B-cell CLL/lymphoma 10
chr7_-_37488777 1.00 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chrX_-_131547596 1.00 ENST00000538204.1
ENST00000370849.3
MBNL3
muscleblind-like splicing regulator 3
chr18_-_60986613 0.99 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr11_+_46740730 0.99 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr4_-_40516560 0.98 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr22_-_39151463 0.98 ENST00000405510.1
ENST00000433561.1
SUN2
Sad1 and UNC84 domain containing 2
chr11_-_65374430 0.98 ENST00000532507.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr17_-_77005801 0.95 ENST00000392446.5
CANT1
calcium activated nucleotidase 1
chr2_+_12857043 0.92 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr6_-_32806483 0.92 ENST00000374899.4
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_152061537 0.92 ENST00000368806.1
TCHHL1
trichohyalin-like 1
chr17_-_77005860 0.90 ENST00000591773.1
ENST00000588611.1
ENST00000586916.2
ENST00000592033.1
ENST00000588075.1
ENST00000302345.2
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr6_-_32095968 0.86 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr2_-_191878162 0.86 ENST00000540176.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr3_+_46283916 0.86 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chr8_+_11666649 0.85 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr17_+_72270380 0.83 ENST00000582036.1
ENST00000307504.5
DNAI2
dynein, axonemal, intermediate chain 2
chr1_-_228594490 0.81 ENST00000366699.3
ENST00000284551.6
TRIM11
tripartite motif containing 11
chr7_+_66386204 0.81 ENST00000341567.4
ENST00000607045.1
TMEM248
transmembrane protein 248
chrX_-_131547625 0.80 ENST00000394311.2
MBNL3
muscleblind-like splicing regulator 3
chr12_-_95945246 0.79 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr21_-_33651324 0.79 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr6_-_130031358 0.79 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr3_+_107318157 0.78 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr18_+_72922710 0.78 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr11_+_20385231 0.77 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr12_-_109221160 0.77 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr16_-_28608364 0.77 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_21022818 0.76 ENST00000440866.2
ENST00000541941.1
ENST00000402479.2
ENST00000435420.2
ENST00000432947.1
ENST00000403006.2
ENST00000419825.2
ENST00000381090.3
ENST00000237822.3
ENST00000412261.1
C2orf43
chromosome 2 open reading frame 43
chr5_-_54988448 0.76 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr16_-_84273304 0.76 ENST00000308251.4
ENST00000568181.1
KCNG4
potassium voltage-gated channel, subfamily G, member 4
chr17_-_77005813 0.76 ENST00000590370.1
ENST00000591625.1
CANT1
calcium activated nucleotidase 1
chr3_-_197476560 0.75 ENST00000273582.5
KIAA0226
KIAA0226
chr18_-_53255766 0.75 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4
transcription factor 4
chr1_-_231376836 0.74 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr9_-_4859260 0.74 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr12_-_2986107 0.73 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
FOXM1
forkhead box M1
chr2_-_208489275 0.72 ENST00000272839.3
ENST00000426075.1
METTL21A
methyltransferase like 21A
chr11_-_67211263 0.72 ENST00000393893.1
CORO1B
coronin, actin binding protein, 1B
chr8_-_144660771 0.72 ENST00000449291.2
NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr20_+_277737 0.72 ENST00000382352.3
ZCCHC3
zinc finger, CCHC domain containing 3
chr14_-_50559361 0.71 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr6_-_32806506 0.71 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr4_+_109571800 0.70 ENST00000512478.2
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr12_-_99288536 0.70 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_231376867 0.70 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
C1orf131
chromosome 1 open reading frame 131
chr14_+_104394770 0.69 ENST00000409874.4
ENST00000339063.5
TDRD9
tudor domain containing 9
chr8_-_116681123 0.69 ENST00000519674.1
TRPS1
trichorhinophalangeal syndrome I
chr19_+_38779778 0.68 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4
serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4
chr3_-_142166904 0.68 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr13_-_28194541 0.68 ENST00000316334.3
LNX2
ligand of numb-protein X 2
chr1_-_151319283 0.68 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr14_+_76072096 0.68 ENST00000555058.1
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr14_+_78227105 0.67 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr10_+_33271469 0.65 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr11_-_62474803 0.64 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_-_230787879 0.63 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr1_-_1624083 0.63 ENST00000378662.1
ENST00000234800.6
SLC35E2B
solute carrier family 35, member E2B
chr18_+_3448455 0.62 ENST00000549780.1
TGIF1
TGFB-induced factor homeobox 1
chr4_+_109571740 0.61 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr19_-_51308175 0.60 ENST00000345523.4
C19orf48
chromosome 19 open reading frame 48
chr11_-_64545222 0.60 ENST00000433274.2
ENST00000432725.1
SF1
splicing factor 1
chr10_-_27703269 0.59 ENST00000438700.3
PTCHD3
patched domain containing 3
chr3_+_119298523 0.58 ENST00000357003.3
ADPRH
ADP-ribosylarginine hydrolase
chr17_+_73089382 0.57 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr10_-_14920599 0.56 ENST00000609399.1
RP11-398C13.6
RP11-398C13.6
chr5_+_150157444 0.55 ENST00000526627.1
SMIM3
small integral membrane protein 3
chr21_+_43934633 0.54 ENST00000398343.2
SLC37A1
solute carrier family 37 (glucose-6-phosphate transporter), member 1
chr5_-_130500922 0.53 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1
histidine triad nucleotide binding protein 1
chr20_-_44993012 0.53 ENST00000372229.1
ENST00000372230.5
ENST00000543605.1
ENST00000243896.2
ENST00000317734.8
SLC35C2
solute carrier family 35 (GDP-fucose transporter), member C2
chr18_-_60987220 0.52 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr1_-_155145721 0.52 ENST00000295682.4
KRTCAP2
keratinocyte associated protein 2
chr18_+_29027696 0.51 ENST00000257189.4
DSG3
desmoglein 3
chr10_-_70092671 0.51 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD
phenazine biosynthesis-like protein domain containing
chr4_+_95128996 0.50 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_176733897 0.48 ENST00000393658.2
GPM6A
glycoprotein M6A
chr18_-_5396271 0.47 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr12_-_57146095 0.46 ENST00000550770.1
ENST00000338193.6
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr15_-_34502278 0.46 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr6_-_113754604 0.45 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr18_+_61254534 0.45 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0071529 cementum mineralization(GO:0071529)
1.3 5.0 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
1.1 3.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.9 2.6 GO:0032831 regulation of tolerance induction dependent upon immune response(GO:0002652) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.8 2.5 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.8 3.1 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.8 6.8 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.7 2.9 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 11.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.6 2.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.6 2.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.5 1.6 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.5 6.3 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 2.0 GO:0060585 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.5 2.0 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.4 1.2 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.4 1.1 GO:0043132 NAD transport(GO:0043132)
0.3 1.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.3 9.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.3 0.9 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.3 1.1 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 1.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 0.8 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.3 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 0.7 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.2 1.9 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 5.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 4.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.0 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.2 1.0 GO:1900738 cytolysis in other organism involved in symbiotic interaction(GO:0051801) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 6.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.9 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 0.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 6.9 GO:0045730 respiratory burst(GO:0045730)
0.2 2.9 GO:0090168 Golgi reassembly(GO:0090168)
0.2 0.8 GO:0060023 soft palate development(GO:0060023)
0.1 17.4 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.1 6.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.4 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 0.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 3.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 5.8 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 1.7 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 5.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 2.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.7 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 1.2 GO:0051014 actin filament severing(GO:0051014)
0.0 1.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 7.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 3.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 3.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 2.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 2.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.8 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 1.2 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 2.6 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 2.3 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 2.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 4.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.5 1.9 GO:0031251 PAN complex(GO:0031251)
0.3 1.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 6.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.2 1.0 GO:0032449 CBM complex(GO:0032449)
0.1 4.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 4.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.2 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 3.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.7 GO:0071547 piP-body(GO:0071547)
0.1 5.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 3.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 5.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 5.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 5.7 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 4.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 5.8 GO:0005769 early endosome(GO:0005769)
0.0 5.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 11.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.3 5.0 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
1.0 2.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.8 3.1 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.6 6.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 4.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.5 8.9 GO:0019957 C-C chemokine binding(GO:0019957)
0.5 2.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.4 6.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 4.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 2.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 1.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.2 5.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 3.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 7.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 0.9 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 2.6 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.0 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 5.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 2.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 0.5 GO:0003896 DNA primase activity(GO:0003896)
0.1 2.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 2.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 3.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 1.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 2.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.6 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 3.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 1.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 2.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 6.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 7.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 7.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.8 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 9.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 5.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 3.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 10.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 7.9 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 5.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 3.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.1 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 3.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors