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Illumina Body Map 2, young vs old

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Results for PAX8

Z-value: 0.12

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Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
PAX8
ENSG00000125618.12 paired box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg19_v2_chr2_-_113999260_113999274-0.345.8e-02Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_22446680 2.27 ENST00000390443.3
TRAV8-6
T cell receptor alpha variable 8-6
chr20_+_44350968 1.74 ENST00000279058.3
SPINT4
serine peptidase inhibitor, Kunitz type 4
chr10_+_85933494 1.58 ENST00000372126.3
C10orf99
chromosome 10 open reading frame 99
chr7_-_142181009 1.54 ENST00000390368.2
TRBV6-5
T cell receptor beta variable 6-5
chr1_+_115642293 1.49 ENST00000448680.1
RP4-666F24.3
RP4-666F24.3
chr1_-_186649543 1.35 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_142428476 1.34 ENST00000390400.2
TRBV28
T cell receptor beta variable 28
chr1_-_161600990 1.29 ENST00000531221.1
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr1_-_161600942 1.19 ENST00000421702.2
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr11_+_60223312 1.13 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chrX_-_151938171 1.07 ENST00000393902.3
ENST00000417212.1
ENST00000370278.3
MAGEA3
melanoma antigen family A, 3
chr14_-_91710852 1.06 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr20_-_42355629 1.06 ENST00000373003.1
GTSF1L
gametocyte specific factor 1-like
chr19_-_7766991 1.05 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr11_+_1092184 1.05 ENST00000361558.6
MUC2
mucin 2, oligomeric mucus/gel-forming
chr14_+_22458631 1.05 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr2_+_217735493 1.05 ENST00000456163.1
AC007557.1
HCG1816075; Uncharacterized protein
chr2_+_90259593 1.05 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr15_+_34638066 1.04 ENST00000333756.4
NUTM1
NUT midline carcinoma, family member 1
chr2_+_185463093 1.04 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr19_-_40228657 1.03 ENST00000221804.4
CLC
Charcot-Leyden crystal galectin
chr11_+_60223225 1.02 ENST00000524807.1
ENST00000345732.4
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr19_+_42301079 1.00 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr6_-_6711235 0.98 ENST00000432823.2
RP1-80N2.2
RP1-80N2.2
chr1_-_25256368 0.97 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr3_-_169587621 0.96 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr1_-_27952741 0.94 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr7_-_142176790 0.92 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr19_+_42300548 0.89 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr6_-_27858570 0.88 ENST00000359303.2
HIST1H3J
histone cluster 1, H3j
chr12_-_92821922 0.86 ENST00000538965.1
ENST00000378487.2
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr6_+_135502501 0.86 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr8_+_7353368 0.82 ENST00000355602.2
DEFB107B
defensin, beta 107B
chr19_-_52254050 0.81 ENST00000600815.1
FPR1
formyl peptide receptor 1
chr11_+_117857063 0.81 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA
interleukin 10 receptor, alpha
chr22_+_22730353 0.81 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr8_-_126963487 0.80 ENST00000518964.1
LINC00861
long intergenic non-protein coding RNA 861
chr17_-_60883993 0.80 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr19_+_12862604 0.79 ENST00000553030.1
BEST2
bestrophin 2
chr2_+_231860830 0.78 ENST00000424440.1
ENST00000452881.1
ENST00000433428.2
ENST00000455816.1
ENST00000440792.1
ENST00000423134.1
SPATA3
spermatogenesis associated 3
chr1_+_160709029 0.78 ENST00000444090.2
ENST00000441662.2
SLAMF7
SLAM family member 7
chr19_-_52133588 0.77 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr1_-_27953031 0.77 ENST00000374003.3
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr6_-_44233361 0.76 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr12_+_18891045 0.75 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr1_-_27952617 0.72 ENST00000457296.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr2_+_79252834 0.72 ENST00000409471.1
REG3G
regenerating islet-derived 3 gamma
chr6_+_135502466 0.72 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr7_+_129984630 0.72 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5
carboxypeptidase A5
chr2_-_79386786 0.71 ENST00000393878.1
ENST00000305165.2
ENST00000409839.3
REG3A
regenerating islet-derived 3 alpha
chr14_-_106054659 0.70 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr14_-_106610852 0.69 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chrX_+_151867214 0.69 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
MAGEA6
melanoma antigen family A, 6
chr5_-_18746250 0.69 ENST00000512978.1
CTD-2023M8.1
CTD-2023M8.1
chr2_+_90198535 0.67 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr12_-_57873631 0.67 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9
Rho GTPase activating protein 9
chr1_+_100817262 0.67 ENST00000455467.1
CDC14A
cell division cycle 14A
chr14_-_23288930 0.67 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_-_20040638 0.65 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chrY_-_13524717 0.64 ENST00000331172.6
SLC9B1P1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr4_-_80329356 0.64 ENST00000358842.3
GK2
glycerol kinase 2
chr16_+_33006369 0.63 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr19_-_39303576 0.63 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chrX_-_153141783 0.63 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr10_+_70847852 0.62 ENST00000242465.3
SRGN
serglycin
chr8_-_57233103 0.61 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr1_-_161600822 0.61 ENST00000534776.1
ENST00000540048.1
FCGR3B
FCGR3A
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr14_+_22931924 0.61 ENST00000390477.2
TRDC
T cell receptor delta constant
chr12_-_18890940 0.60 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr12_-_123201337 0.60 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_123187890 0.59 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr8_-_7673238 0.59 ENST00000335021.2
DEFB107A
defensin, beta 107A
chr2_+_90248739 0.59 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr4_+_71091786 0.58 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr2_+_79252822 0.58 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chr1_-_85156417 0.58 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr16_-_28518153 0.57 ENST00000356897.1
IL27
interleukin 27
chr22_-_37403839 0.57 ENST00000402860.3
ENST00000381821.1
TEX33
testis expressed 33
chr6_+_41196077 0.56 ENST00000448827.2
TREML4
triggering receptor expressed on myeloid cells-like 4
chr22_-_37403858 0.56 ENST00000405091.2
TEX33
testis expressed 33
chr4_+_36283213 0.55 ENST00000357504.3
DTHD1
death domain containing 1
chr1_-_157522260 0.55 ENST00000368191.3
ENST00000361835.3
FCRL5
Fc receptor-like 5
chr8_-_21771182 0.55 ENST00000523932.1
ENST00000544659.1
DOK2
docking protein 2, 56kDa
chr4_-_46911223 0.55 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr2_+_79252804 0.55 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr6_+_41196052 0.54 ENST00000341495.2
TREML4
triggering receptor expressed on myeloid cells-like 4
chr16_-_20367584 0.54 ENST00000570689.1
UMOD
uromodulin
chr22_+_23029188 0.53 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr19_-_51538148 0.53 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr14_-_107114267 0.53 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr1_-_223853425 0.52 ENST00000366873.2
ENST00000419193.2
CAPN8
calpain 8
chr19_+_17865011 0.52 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr11_+_4510109 0.51 ENST00000307632.3
OR52K1
olfactory receptor, family 52, subfamily K, member 1
chr4_-_16077741 0.51 ENST00000447510.2
ENST00000540805.1
ENST00000539194.1
PROM1
prominin 1
chr11_+_60739249 0.51 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6
CD6 molecule
chr3_-_6847096 0.51 ENST00000454410.2
ENST00000424366.1
ENST00000417482.1
ENST00000412629.1
GRM7-AS3
GRM7 antisense RNA 3
chr9_+_111624577 0.50 ENST00000333999.3
ACTL7A
actin-like 7A
chr1_-_16730469 0.49 ENST00000491418.1
SPATA21
spermatogenesis associated 21
chr1_+_182419261 0.49 ENST00000294854.8
ENST00000542961.1
RGSL1
regulator of G-protein signaling like 1
chr5_-_156390230 0.49 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr6_+_135502408 0.49 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr1_-_173176452 0.49 ENST00000281834.3
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr14_+_23004404 0.48 ENST00000390528.1
TRAJ9
T cell receptor alpha joining 9
chr2_+_90192768 0.48 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr6_+_43266063 0.48 ENST00000372574.3
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr2_-_79313973 0.47 ENST00000454188.1
REG1B
regenerating islet-derived 1 beta
chr8_-_121825088 0.47 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_+_35939154 0.47 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr20_+_2795626 0.47 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr3_-_128684488 0.46 ENST00000511204.1
RP11-723O4.6
Uncharacterized protein FLJ43738
chr12_-_21556577 0.46 ENST00000450590.1
ENST00000453443.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr7_-_15014398 0.45 ENST00000437998.1
DGKB
diacylglycerol kinase, beta 90kDa
chr17_+_38444115 0.45 ENST00000580824.1
ENST00000577249.1
CDC6
cell division cycle 6
chr6_+_142623758 0.45 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chr11_-_104905840 0.44 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr19_-_51537982 0.44 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr16_+_63764128 0.43 ENST00000563061.1
RP11-370P15.2
RP11-370P15.2
chr6_+_117198400 0.43 ENST00000332958.2
RFX6
regulatory factor X, 6
chr1_+_186649754 0.43 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr4_+_75230853 0.42 ENST00000244869.2
EREG
epiregulin
chr6_-_32784687 0.42 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr22_+_22707260 0.42 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr7_-_144533074 0.41 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr22_+_27017921 0.41 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr17_-_34257771 0.40 ENST00000394529.3
ENST00000293273.6
RDM1
RAD52 motif 1
chr1_+_100818156 0.40 ENST00000336454.3
CDC14A
cell division cycle 14A
chr3_+_164924716 0.40 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
RP11-85M11.2
chrX_+_151883090 0.39 ENST00000370293.2
ENST00000423993.1
ENST00000447530.1
ENST00000458057.1
ENST00000331220.2
ENST00000422085.1
ENST00000453150.1
ENST00000409560.1
MAGEA2B
melanoma antigen family A, 2B
chr4_-_145061788 0.39 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA
GYPB
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr3_+_190105909 0.39 ENST00000456423.1
CLDN16
claudin 16
chr3_+_125694347 0.39 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr17_-_34257731 0.38 ENST00000431884.2
ENST00000425909.3
ENST00000394528.3
ENST00000430160.2
RDM1
RAD52 motif 1
chr6_+_30130969 0.38 ENST00000376694.4
TRIM15
tripartite motif containing 15
chr2_+_98993751 0.38 ENST00000409937.1
CNGA3
cyclic nucleotide gated channel alpha 3
chr19_-_54804173 0.38 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr9_-_116837249 0.37 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr11_-_58343319 0.37 ENST00000395074.2
LPXN
leupaxin
chr3_-_150264272 0.37 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr1_-_198509804 0.36 ENST00000489986.1
ENST00000367382.1
ATP6V1G3
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr19_-_51538118 0.36 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chrX_-_152160740 0.36 ENST00000361887.5
ENST00000439251.1
ENST00000452693.1
PNMA5
paraneoplastic Ma antigen family member 5
chr6_-_9939552 0.36 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr13_+_31309645 0.36 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr6_+_29274403 0.36 ENST00000377160.2
OR14J1
olfactory receptor, family 14, subfamily J, member 1
chr3_+_121796697 0.36 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr3_+_186435137 0.35 ENST00000447445.1
KNG1
kininogen 1
chr2_-_234763147 0.35 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
HJURP
Holliday junction recognition protein
chr20_+_31547651 0.35 ENST00000457731.1
EFCAB8
EF-hand calcium binding domain 8
chrX_+_134887233 0.35 ENST00000443882.1
CT45A3
cancer/testis antigen family 45, member A3
chr19_-_6057282 0.34 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr15_+_45028520 0.34 ENST00000329464.4
TRIM69
tripartite motif containing 69
chr7_+_12544025 0.34 ENST00000443874.1
ENST00000424453.1
AC005281.1
AC005281.1
chr14_+_22962898 0.34 ENST00000390492.1
TRAJ45
T cell receptor alpha joining 45
chr7_+_150413645 0.33 ENST00000307194.5
GIMAP1
GTPase, IMAP family member 1
chr1_-_157522180 0.33 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5
Fc receptor-like 5
chr3_-_111852128 0.33 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr2_-_26864228 0.33 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr20_+_2795609 0.33 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr12_-_6961050 0.33 ENST00000538862.2
CDCA3
cell division cycle associated 3
chr8_+_31496809 0.32 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr8_-_71157595 0.32 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chrX_+_55649833 0.32 ENST00000339140.3
FOXR2
forkhead box R2
chr6_-_138060103 0.31 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1
RP11-356I2.1
chr2_-_132589601 0.31 ENST00000437330.1
AC103564.7
AC103564.7
chr12_-_129308487 0.31 ENST00000266771.5
SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
chr6_+_14117872 0.31 ENST00000379153.3
CD83
CD83 molecule
chr11_+_64323156 0.31 ENST00000377585.3
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr12_-_53074182 0.31 ENST00000252244.3
KRT1
keratin 1
chr12_-_110883346 0.30 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr18_+_6511415 0.30 ENST00000584361.1
RP11-865B13.1
chromosome 18 open reading frame 64
chr16_-_86383240 0.30 ENST00000595169.1
ENST00000598994.1
ENST00000599619.1
ENST00000599664.1
LINC00917
long intergenic non-protein coding RNA 917
chr10_+_96443378 0.30 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr12_-_57410304 0.30 ENST00000441881.1
ENST00000458521.2
TAC3
tachykinin 3
chr14_+_58797974 0.30 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr21_-_32410795 0.29 ENST00000382822.2
KRTAP19-8
keratin associated protein 19-8
chr1_+_180165672 0.28 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr13_+_24844979 0.28 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr12_+_75874460 0.28 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr12_-_89919965 0.28 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr8_+_27168988 0.28 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr6_-_51952367 0.28 ENST00000340994.4
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr16_-_87350970 0.28 ENST00000567970.1
C16orf95
chromosome 16 open reading frame 95
chrX_-_153141434 0.27 ENST00000407935.2
ENST00000439496.1
L1CAM
L1 cell adhesion molecule
chr13_-_103426112 0.27 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr17_-_39646116 0.27 ENST00000328119.6
KRT36
keratin 36
chr22_-_31324215 0.26 ENST00000429468.1
MORC2
MORC family CW-type zinc finger 2
chrX_-_131228291 0.26 ENST00000370879.1
FRMD7
FERM domain containing 7
chr15_-_73925651 0.26 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN
neuroplastin
chr3_-_189840223 0.26 ENST00000427335.2
LEPREL1
leprecan-like 1
chrX_+_23925918 0.25 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr15_-_49255632 0.25 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr11_+_9482512 0.25 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr14_+_101123580 0.25 ENST00000556697.1
ENST00000360899.2
ENST00000553623.1
LINC00523
long intergenic non-protein coding RNA 523
chr13_+_51483814 0.25 ENST00000336617.3
ENST00000422660.1
RNASEH2B
ribonuclease H2, subunit B
chrX_-_151903184 0.24 ENST00000357916.4
ENST00000393869.3
MAGEA12
melanoma antigen family A, 12
chr5_-_140027357 0.23 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr4_+_120860695 0.23 ENST00000505122.2
RP11-700N1.1
RP11-700N1.1
chr15_+_45021183 0.23 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr12_-_6960407 0.23 ENST00000540683.1
ENST00000229265.6
ENST00000535406.1
ENST00000422785.3
CDCA3
cell division cycle associated 3
chr14_+_66578299 0.23 ENST00000554187.1
ENST00000556662.1
ENST00000556291.1
ENST00000557723.1
ENST00000557050.1
RP11-783L4.1
RP11-783L4.1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.6 1.9 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.4 1.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.6 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 1.1 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.5 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.4 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.4 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.1 0.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.4 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.3 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.5 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 2.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.9 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.9 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.7 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.7 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.8 GO:0042940 D-amino acid transport(GO:0042940)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 2.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.6 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 3.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.4 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 3.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.5 GO:0042100 B cell proliferation(GO:0042100)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.0 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.4 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 1.6 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.2 0.7 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.1 GO:0060091 kinocilium(GO:0060091)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.6 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 2.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.3 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 0.6 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 3.6 GO:0019864 IgG binding(GO:0019864)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 2.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.1 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 1.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.4 GO:0019862 IgA binding(GO:0019862)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 1.2 GO:0089720 caspase binding(GO:0089720)
0.1 0.8 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 2.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.3 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 3.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.3 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 1.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 3.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling