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Illumina Body Map 2, young vs old
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Results for PBX1
Z-value: 0.36
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Transcription factors associated with PBX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PBX1
|
ENSG00000185630.14 | PBX homeobox 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PBX1 | hg19_v2_chr1_+_164528616_164528660 | -0.39 | 2.7e-02 | Click! |
Activity profile of PBX1 motif
Sorted Z-values of PBX1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_29171689 | 7.63 |
ENST00000237014.3
|
TTR
|
transthyretin |
| chr4_-_72649763 | 5.10 |
ENST00000513476.1
|
GC
|
group-specific component (vitamin D binding protein) |
| chr17_-_26694979 | 4.60 |
ENST00000438614.1
|
VTN
|
vitronectin |
| chr17_-_26695013 | 4.46 |
ENST00000555059.2
|
CTB-96E2.2
|
Homeobox protein SEBOX |
| chr13_-_46679144 | 3.96 |
ENST00000181383.4
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr13_-_46679185 | 3.84 |
ENST00000439329.3
|
CPB2
|
carboxypeptidase B2 (plasma) |
| chr4_+_69962185 | 3.75 |
ENST00000305231.7
|
UGT2B7
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
| chr12_+_20968608 | 3.59 |
ENST00000381541.3
ENST00000540229.1 ENST00000553473.1 ENST00000554957.1 |
LST3
SLCO1B3
SLCO1B7
|
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein solute carrier organic anion transporter family, member 1B3 solute carrier organic anion transporter family, member 1B7 (non-functional) |
| chr2_-_88427568 | 3.56 |
ENST00000393750.3
ENST00000295834.3 |
FABP1
|
fatty acid binding protein 1, liver |
| chr4_+_69962212 | 3.51 |
ENST00000508661.1
|
UGT2B7
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
| chr12_+_81471816 | 3.20 |
ENST00000261206.3
|
ACSS3
|
acyl-CoA synthetase short-chain family member 3 |
| chr19_-_16008880 | 3.13 |
ENST00000011989.7
ENST00000221700.6 |
CYP4F2
|
cytochrome P450, family 4, subfamily F, polypeptide 2 |
| chr4_+_69681710 | 3.13 |
ENST00000265403.7
ENST00000458688.2 |
UGT2B10
|
UDP glucuronosyltransferase 2 family, polypeptide B10 |
| chr2_+_211342432 | 2.65 |
ENST00000430249.2
|
CPS1
|
carbamoyl-phosphate synthase 1, mitochondrial |
| chr10_-_101190202 | 2.50 |
ENST00000543866.1
ENST00000370508.5 |
GOT1
|
glutamic-oxaloacetic transaminase 1, soluble |
| chr4_+_187148556 | 2.40 |
ENST00000264690.6
ENST00000446598.2 ENST00000414291.1 ENST00000513864.1 |
KLKB1
|
kallikrein B, plasma (Fletcher factor) 1 |
| chr5_-_42825983 | 2.37 |
ENST00000506577.1
|
SEPP1
|
selenoprotein P, plasma, 1 |
| chr10_+_5238793 | 2.35 |
ENST00000263126.1
|
AKR1C4
|
aldo-keto reductase family 1, member C4 |
| chr2_+_234600253 | 2.19 |
ENST00000373424.1
ENST00000441351.1 |
UGT1A6
|
UDP glucuronosyltransferase 1 family, polypeptide A6 |
| chr4_-_69536346 | 2.18 |
ENST00000338206.5
|
UGT2B15
|
UDP glucuronosyltransferase 2 family, polypeptide B15 |
| chr6_+_25754927 | 2.15 |
ENST00000377905.4
ENST00000439485.2 |
SLC17A4
|
solute carrier family 17, member 4 |
| chrM_+_4431 | 2.15 |
ENST00000361453.3
|
MT-ND2
|
mitochondrially encoded NADH dehydrogenase 2 |
| chr12_+_21679220 | 2.13 |
ENST00000256969.2
|
C12orf39
|
chromosome 12 open reading frame 39 |
| chr4_-_70080449 | 2.12 |
ENST00000446444.1
|
UGT2B11
|
UDP glucuronosyltransferase 2 family, polypeptide B11 |
| chr14_-_74551096 | 1.94 |
ENST00000350259.4
|
ALDH6A1
|
aldehyde dehydrogenase 6 family, member A1 |
| chr10_+_96522361 | 1.86 |
ENST00000371321.3
|
CYP2C19
|
cytochrome P450, family 2, subfamily C, polypeptide 19 |
| chr11_+_22689648 | 1.85 |
ENST00000278187.3
|
GAS2
|
growth arrest-specific 2 |
| chr19_-_15590306 | 1.84 |
ENST00000292609.4
|
PGLYRP2
|
peptidoglycan recognition protein 2 |
| chr11_-_2162162 | 1.83 |
ENST00000381389.1
|
IGF2
|
insulin-like growth factor 2 (somatomedin A) |
| chr7_+_107110488 | 1.82 |
ENST00000304402.4
|
GPR22
|
G protein-coupled receptor 22 |
| chr18_-_48346298 | 1.79 |
ENST00000398439.3
|
MRO
|
maestro |
| chr14_-_74551172 | 1.79 |
ENST00000553458.1
|
ALDH6A1
|
aldehyde dehydrogenase 6 family, member A1 |
| chrM_-_14670 | 1.77 |
ENST00000361681.2
|
MT-ND6
|
mitochondrially encoded NADH dehydrogenase 6 |
| chr18_-_48346415 | 1.70 |
ENST00000431965.2
ENST00000436348.2 |
MRO
|
maestro |
| chr17_+_4853442 | 1.68 |
ENST00000522301.1
|
ENO3
|
enolase 3 (beta, muscle) |
| chr17_-_38821373 | 1.65 |
ENST00000394052.3
|
KRT222
|
keratin 222 |
| chr3_+_159557637 | 1.58 |
ENST00000445224.2
|
SCHIP1
|
schwannomin interacting protein 1 |
| chr5_+_166711804 | 1.57 |
ENST00000518659.1
ENST00000545108.1 |
TENM2
|
teneurin transmembrane protein 2 |
| chr6_-_110736742 | 1.57 |
ENST00000368924.3
ENST00000368923.3 |
DDO
|
D-aspartate oxidase |
| chr4_+_77356248 | 1.55 |
ENST00000296043.6
|
SHROOM3
|
shroom family member 3 |
| chr10_+_24738355 | 1.53 |
ENST00000307544.6
|
KIAA1217
|
KIAA1217 |
| chr8_+_99076509 | 1.52 |
ENST00000318528.3
|
C8orf47
|
chromosome 8 open reading frame 47 |
| chr11_+_114166536 | 1.52 |
ENST00000299964.3
|
NNMT
|
nicotinamide N-methyltransferase |
| chr12_-_96389702 | 1.50 |
ENST00000552509.1
|
HAL
|
histidine ammonia-lyase |
| chr8_+_99076750 | 1.49 |
ENST00000545282.1
|
C8orf47
|
chromosome 8 open reading frame 47 |
| chr6_-_26124138 | 1.48 |
ENST00000314332.5
ENST00000396984.1 |
HIST1H2BC
|
histone cluster 1, H2bc |
| chr14_+_24584056 | 1.48 |
ENST00000561001.1
|
DCAF11
|
DDB1 and CUL4 associated factor 11 |
| chr7_-_120498357 | 1.45 |
ENST00000415871.1
ENST00000222747.3 ENST00000430985.1 |
TSPAN12
|
tetraspanin 12 |
| chr1_+_156589198 | 1.43 |
ENST00000456112.1
|
HAPLN2
|
hyaluronan and proteoglycan link protein 2 |
| chr15_-_54025300 | 1.43 |
ENST00000559418.1
|
WDR72
|
WD repeat domain 72 |
| chr18_+_44526744 | 1.42 |
ENST00000585469.1
|
KATNAL2
|
katanin p60 subunit A-like 2 |
| chr14_+_24584372 | 1.38 |
ENST00000559396.1
ENST00000558638.1 ENST00000561041.1 ENST00000559288.1 ENST00000558408.1 |
DCAF11
|
DDB1 and CUL4 associated factor 11 |
| chr5_-_125930877 | 1.37 |
ENST00000510111.2
ENST00000509270.1 |
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1 |
| chrM_+_14741 | 1.37 |
ENST00000361789.2
|
MT-CYB
|
mitochondrially encoded cytochrome b |
| chr5_+_43602750 | 1.36 |
ENST00000505678.2
ENST00000512422.1 ENST00000264663.5 |
NNT
|
nicotinamide nucleotide transhydrogenase |
| chr19_-_33360647 | 1.34 |
ENST00000590341.1
ENST00000587772.1 ENST00000023064.4 |
SLC7A9
|
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| chr2_-_200323414 | 1.27 |
ENST00000443023.1
|
SATB2
|
SATB homeobox 2 |
| chr11_-_126870683 | 1.24 |
ENST00000525704.2
|
KIRREL3
|
kin of IRRE like 3 (Drosophila) |
| chr14_+_24583836 | 1.24 |
ENST00000559115.1
ENST00000558215.1 ENST00000557810.1 ENST00000561375.1 ENST00000446197.3 ENST00000559796.1 ENST00000560713.1 ENST00000560901.1 ENST00000559382.1 |
DCAF11
|
DDB1 and CUL4 associated factor 11 |
| chr17_+_58018269 | 1.24 |
ENST00000591035.1
|
RP11-178C3.1
|
Uncharacterized protein |
| chr5_+_43603229 | 1.24 |
ENST00000344920.4
ENST00000512996.2 |
NNT
|
nicotinamide nucleotide transhydrogenase |
| chr8_-_42360015 | 1.23 |
ENST00000522707.1
|
SLC20A2
|
solute carrier family 20 (phosphate transporter), member 2 |
| chr5_-_125930929 | 1.21 |
ENST00000553117.1
ENST00000447989.2 ENST00000409134.3 |
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1 |
| chr8_-_36636676 | 1.20 |
ENST00000524132.1
ENST00000519451.1 |
RP11-962G15.1
|
RP11-962G15.1 |
| chr22_+_29138013 | 1.16 |
ENST00000216027.3
ENST00000398941.2 |
HSCB
|
HscB mitochondrial iron-sulfur cluster co-chaperone |
| chr12_+_79258444 | 1.16 |
ENST00000261205.4
|
SYT1
|
synaptotagmin I |
| chr4_-_152147579 | 1.15 |
ENST00000304527.4
ENST00000455740.1 ENST00000424281.1 ENST00000409598.4 |
SH3D19
|
SH3 domain containing 19 |
| chr16_+_7560114 | 1.10 |
ENST00000570626.1
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr18_+_44526786 | 1.08 |
ENST00000245121.5
ENST00000356157.7 |
KATNAL2
|
katanin p60 subunit A-like 2 |
| chr4_-_6557336 | 1.05 |
ENST00000507294.1
|
PPP2R2C
|
protein phosphatase 2, regulatory subunit B, gamma |
| chr9_+_140135665 | 1.04 |
ENST00000340384.4
|
TUBB4B
|
tubulin, beta 4B class IVb |
| chr4_-_186570679 | 1.02 |
ENST00000451974.1
|
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr3_+_159570722 | 1.02 |
ENST00000482804.1
|
SCHIP1
|
schwannomin interacting protein 1 |
| chr14_+_50234309 | 1.02 |
ENST00000298307.5
|
KLHDC2
|
kelch domain containing 2 |
| chrM_+_9207 | 1.00 |
ENST00000362079.2
|
MT-CO3
|
mitochondrially encoded cytochrome c oxidase III |
| chr11_-_126870655 | 1.00 |
ENST00000525144.2
|
KIRREL3
|
kin of IRRE like 3 (Drosophila) |
| chr11_+_34938119 | 0.99 |
ENST00000227868.4
ENST00000430469.2 ENST00000533262.1 |
PDHX
|
pyruvate dehydrogenase complex, component X |
| chr4_-_186682716 | 0.98 |
ENST00000445343.1
|
SORBS2
|
sorbin and SH3 domain containing 2 |
| chr5_-_43313574 | 0.97 |
ENST00000325110.6
ENST00000433297.2 |
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| chr15_-_37393406 | 0.96 |
ENST00000338564.5
ENST00000558313.1 ENST00000340545.5 |
MEIS2
|
Meis homeobox 2 |
| chr1_+_156589051 | 0.95 |
ENST00000255039.1
|
HAPLN2
|
hyaluronan and proteoglycan link protein 2 |
| chr8_-_91095099 | 0.94 |
ENST00000265431.3
|
CALB1
|
calbindin 1, 28kDa |
| chr3_+_139063372 | 0.94 |
ENST00000478464.1
|
MRPS22
|
mitochondrial ribosomal protein S22 |
| chr2_-_158182410 | 0.93 |
ENST00000419116.2
ENST00000410096.1 |
ERMN
|
ermin, ERM-like protein |
| chr6_+_26124373 | 0.91 |
ENST00000377791.2
ENST00000602637.1 |
HIST1H2AC
|
histone cluster 1, H2ac |
| chr12_-_39734783 | 0.89 |
ENST00000552961.1
|
KIF21A
|
kinesin family member 21A |
| chr10_+_69865866 | 0.88 |
ENST00000354393.2
|
MYPN
|
myopalladin |
| chr14_-_64971893 | 0.87 |
ENST00000555220.1
|
ZBTB25
|
zinc finger and BTB domain containing 25 |
| chr13_-_48612067 | 0.87 |
ENST00000543413.1
|
SUCLA2
|
succinate-CoA ligase, ADP-forming, beta subunit |
| chr20_+_48909240 | 0.84 |
ENST00000371639.3
|
RP11-290F20.1
|
RP11-290F20.1 |
| chr2_-_200322723 | 0.84 |
ENST00000417098.1
|
SATB2
|
SATB homeobox 2 |
| chr17_+_1665345 | 0.83 |
ENST00000576406.1
ENST00000571149.1 |
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| chr10_+_95517660 | 0.83 |
ENST00000371413.3
|
LGI1
|
leucine-rich, glioma inactivated 1 |
| chr20_+_58203664 | 0.82 |
ENST00000541461.1
|
PHACTR3
|
phosphatase and actin regulator 3 |
| chr10_+_69869237 | 0.82 |
ENST00000373675.3
|
MYPN
|
myopalladin |
| chr1_+_205473720 | 0.81 |
ENST00000429964.2
ENST00000506784.1 ENST00000360066.2 |
CDK18
|
cyclin-dependent kinase 18 |
| chr3_+_186743261 | 0.80 |
ENST00000423451.1
ENST00000446170.1 |
ST6GAL1
|
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| chr12_+_21525818 | 0.80 |
ENST00000240652.3
ENST00000542023.1 ENST00000537593.1 |
IAPP
|
islet amyloid polypeptide |
| chr16_+_19222479 | 0.79 |
ENST00000568433.1
|
SYT17
|
synaptotagmin XVII |
| chr3_-_129375556 | 0.79 |
ENST00000510323.1
|
TMCC1
|
transmembrane and coiled-coil domain family 1 |
| chr4_+_83956237 | 0.79 |
ENST00000264389.2
|
COPS4
|
COP9 signalosome subunit 4 |
| chr10_-_5227096 | 0.78 |
ENST00000488756.1
ENST00000334314.3 |
AKR1CL1
|
aldo-keto reductase family 1, member C-like 1 |
| chr3_-_178103144 | 0.78 |
ENST00000417383.1
ENST00000418585.1 ENST00000411727.1 ENST00000439810.1 |
RP11-33A14.1
|
RP11-33A14.1 |
| chr10_-_18948208 | 0.78 |
ENST00000607346.1
|
ARL5B-AS1
|
ARL5B antisense RNA 1 |
| chr16_+_69458537 | 0.77 |
ENST00000515314.1
ENST00000561792.1 ENST00000568237.1 |
CYB5B
|
cytochrome b5 type B (outer mitochondrial membrane) |
| chr4_+_83956312 | 0.76 |
ENST00000509317.1
ENST00000503682.1 ENST00000511653.1 |
COPS4
|
COP9 signalosome subunit 4 |
| chr2_+_79412357 | 0.76 |
ENST00000466387.1
|
CTNNA2
|
catenin (cadherin-associated protein), alpha 2 |
| chr2_+_44396000 | 0.75 |
ENST00000409895.4
ENST00000409432.3 ENST00000282412.4 ENST00000378551.2 ENST00000345249.4 |
PPM1B
|
protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| chr4_+_118349545 | 0.74 |
ENST00000422145.3
ENST00000437514.1 |
AC092661.1
|
AC092661.1 |
| chr10_+_95517616 | 0.74 |
ENST00000371418.4
|
LGI1
|
leucine-rich, glioma inactivated 1 |
| chr17_-_57604227 | 0.73 |
ENST00000584262.1
|
RP11-567L7.6
|
RP11-567L7.6 |
| chr4_-_48014931 | 0.71 |
ENST00000420489.2
ENST00000504722.1 |
CNGA1
|
cyclic nucleotide gated channel alpha 1 |
| chr6_-_84417633 | 0.71 |
ENST00000521931.1
|
SNAP91
|
synaptosomal-associated protein, 91kDa |
| chrX_+_139791917 | 0.71 |
ENST00000607004.1
ENST00000370535.3 |
LINC00632
|
long intergenic non-protein coding RNA 632 |
| chr12_-_56848426 | 0.70 |
ENST00000257979.4
|
MIP
|
major intrinsic protein of lens fiber |
| chr9_-_73736511 | 0.70 |
ENST00000377110.3
ENST00000377111.2 |
TRPM3
|
transient receptor potential cation channel, subfamily M, member 3 |
| chr10_+_114043493 | 0.69 |
ENST00000369422.3
|
TECTB
|
tectorin beta |
| chrX_+_120181457 | 0.69 |
ENST00000328078.1
|
GLUD2
|
glutamate dehydrogenase 2 |
| chr17_+_46125685 | 0.68 |
ENST00000579889.1
|
NFE2L1
|
nuclear factor, erythroid 2-like 1 |
| chr2_+_201242715 | 0.68 |
ENST00000421573.1
|
SPATS2L
|
spermatogenesis associated, serine-rich 2-like |
| chr12_+_79258547 | 0.67 |
ENST00000457153.2
|
SYT1
|
synaptotagmin I |
| chr21_+_44313375 | 0.67 |
ENST00000354250.2
ENST00000340344.4 |
NDUFV3
|
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa |
| chr4_-_70626430 | 0.67 |
ENST00000310613.3
|
SULT1B1
|
sulfotransferase family, cytosolic, 1B, member 1 |
| chrX_+_125953746 | 0.67 |
ENST00000371125.3
|
CXorf64
|
chromosome X open reading frame 64 |
| chr12_+_21168630 | 0.65 |
ENST00000421593.2
|
SLCO1B7
|
solute carrier organic anion transporter family, member 1B7 (non-functional) |
| chr12_-_106477805 | 0.65 |
ENST00000553094.1
ENST00000549704.1 |
NUAK1
|
NUAK family, SNF1-like kinase, 1 |
| chr13_-_33760216 | 0.65 |
ENST00000255486.4
|
STARD13
|
StAR-related lipid transfer (START) domain containing 13 |
| chr21_+_27543175 | 0.64 |
ENST00000608591.1
ENST00000609365.1 |
AP000230.1
|
AP000230.1 |
| chr13_+_95254085 | 0.64 |
ENST00000376958.4
|
GPR180
|
G protein-coupled receptor 180 |
| chr21_-_35014027 | 0.63 |
ENST00000399442.1
ENST00000413017.2 ENST00000445393.1 ENST00000417979.1 ENST00000426935.1 ENST00000381540.3 ENST00000361534.2 ENST00000381554.3 |
CRYZL1
|
crystallin, zeta (quinone reductase)-like 1 |
| chr4_-_140005341 | 0.62 |
ENST00000379549.2
ENST00000512627.1 |
ELF2
|
E74-like factor 2 (ets domain transcription factor) |
| chr2_-_158182322 | 0.62 |
ENST00000420719.2
ENST00000409216.1 |
ERMN
|
ermin, ERM-like protein |
| chr16_+_15596123 | 0.62 |
ENST00000452191.2
|
C16orf45
|
chromosome 16 open reading frame 45 |
| chr19_-_51141196 | 0.61 |
ENST00000338916.4
|
SYT3
|
synaptotagmin III |
| chr3_+_148508845 | 0.61 |
ENST00000491148.1
|
CPB1
|
carboxypeptidase B1 (tissue) |
| chr5_-_133702761 | 0.60 |
ENST00000521118.1
ENST00000265334.4 ENST00000435211.1 |
CDKL3
|
cyclin-dependent kinase-like 3 |
| chr2_+_201242941 | 0.59 |
ENST00000449647.1
|
SPATS2L
|
spermatogenesis associated, serine-rich 2-like |
| chr5_+_68513622 | 0.58 |
ENST00000512880.1
ENST00000602380.1 |
MRPS36
|
mitochondrial ribosomal protein S36 |
| chr10_+_60028818 | 0.58 |
ENST00000333926.5
|
CISD1
|
CDGSH iron sulfur domain 1 |
| chr9_-_32573130 | 0.57 |
ENST00000350021.2
ENST00000379847.3 |
NDUFB6
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| chr6_-_84418432 | 0.56 |
ENST00000519825.1
ENST00000523484.2 |
SNAP91
|
synaptosomal-associated protein, 91kDa |
| chr14_-_36536396 | 0.56 |
ENST00000546376.1
|
RP11-116N8.4
|
RP11-116N8.4 |
| chr10_+_95517566 | 0.56 |
ENST00000542308.1
|
LGI1
|
leucine-rich, glioma inactivated 1 |
| chr1_-_238108575 | 0.55 |
ENST00000604646.1
|
MTRNR2L11
|
MT-RNR2-like 11 (pseudogene) |
| chr10_+_18689637 | 0.55 |
ENST00000377315.4
|
CACNB2
|
calcium channel, voltage-dependent, beta 2 subunit |
| chr12_-_133787772 | 0.55 |
ENST00000545350.1
|
AC226150.4
|
Uncharacterized protein |
| chr14_-_24584138 | 0.55 |
ENST00000558280.1
ENST00000561028.1 |
NRL
|
neural retina leucine zipper |
| chr9_-_101471479 | 0.54 |
ENST00000259455.2
|
GABBR2
|
gamma-aminobutyric acid (GABA) B receptor, 2 |
| chr6_-_167040693 | 0.53 |
ENST00000366863.2
|
RPS6KA2
|
ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| chrX_-_92928557 | 0.53 |
ENST00000373079.3
ENST00000475430.2 |
NAP1L3
|
nucleosome assembly protein 1-like 3 |
| chr12_-_10962767 | 0.50 |
ENST00000240691.2
|
TAS2R9
|
taste receptor, type 2, member 9 |
| chr6_+_36839616 | 0.50 |
ENST00000359359.2
ENST00000510325.2 |
C6orf89
|
chromosome 6 open reading frame 89 |
| chrX_-_63005405 | 0.50 |
ENST00000374878.1
ENST00000437457.2 |
ARHGEF9
|
Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| chr4_-_105416039 | 0.49 |
ENST00000394767.2
|
CXXC4
|
CXXC finger protein 4 |
| chr4_-_140005443 | 0.48 |
ENST00000510408.1
ENST00000420916.2 ENST00000358635.3 |
ELF2
|
E74-like factor 2 (ets domain transcription factor) |
| chr12_+_123944070 | 0.47 |
ENST00000412157.2
|
SNRNP35
|
small nuclear ribonucleoprotein 35kDa (U11/U12) |
| chr12_-_54653313 | 0.47 |
ENST00000550411.1
ENST00000439541.2 |
CBX5
|
chromobox homolog 5 |
| chr6_-_167040731 | 0.47 |
ENST00000265678.4
|
RPS6KA2
|
ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| chr13_+_97928395 | 0.44 |
ENST00000445661.2
|
MBNL2
|
muscleblind-like splicing regulator 2 |
| chr19_-_5903714 | 0.44 |
ENST00000586349.1
ENST00000585661.1 ENST00000308961.4 ENST00000592634.1 ENST00000418389.2 ENST00000252675.5 |
AC024592.12
NDUFA11
FUT5
|
Uncharacterized protein NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa fucosyltransferase 5 (alpha (1,3) fucosyltransferase) |
| chr2_-_158182105 | 0.43 |
ENST00000409925.1
|
ERMN
|
ermin, ERM-like protein |
| chr14_+_88851874 | 0.43 |
ENST00000393545.4
ENST00000356583.5 ENST00000555401.1 ENST00000553885.1 |
SPATA7
|
spermatogenesis associated 7 |
| chr19_+_12203100 | 0.43 |
ENST00000596883.1
|
ZNF788
|
zinc finger family member 788 |
| chr5_-_86708833 | 0.42 |
ENST00000256897.4
|
CCNH
|
cyclin H |
| chr9_-_14308004 | 0.42 |
ENST00000493697.1
|
NFIB
|
nuclear factor I/B |
| chr16_-_63651939 | 0.42 |
ENST00000563855.1
ENST00000568932.1 ENST00000564290.1 |
RP11-368L12.1
|
RP11-368L12.1 |
| chr3_-_169587621 | 0.42 |
ENST00000523069.1
ENST00000316428.5 ENST00000264676.5 |
LRRC31
|
leucine rich repeat containing 31 |
| chr17_+_46125707 | 0.41 |
ENST00000584137.1
ENST00000362042.3 ENST00000585291.1 ENST00000357480.5 |
NFE2L1
|
nuclear factor, erythroid 2-like 1 |
| chr4_-_184241927 | 0.40 |
ENST00000323319.5
|
CLDN22
|
claudin 22 |
| chr15_+_36871983 | 0.39 |
ENST00000437989.2
ENST00000569302.1 |
C15orf41
|
chromosome 15 open reading frame 41 |
| chrM_+_10053 | 0.39 |
ENST00000361227.2
|
MT-ND3
|
mitochondrially encoded NADH dehydrogenase 3 |
| chr6_+_99282570 | 0.39 |
ENST00000328345.5
|
POU3F2
|
POU class 3 homeobox 2 |
| chr22_+_29834572 | 0.38 |
ENST00000354373.2
|
RFPL1
|
ret finger protein-like 1 |
| chr1_-_3713042 | 0.38 |
ENST00000378251.1
|
LRRC47
|
leucine rich repeat containing 47 |
| chr16_+_19079215 | 0.38 |
ENST00000544894.2
ENST00000561858.1 |
COQ7
|
coenzyme Q7 homolog, ubiquinone (yeast) |
| chr19_+_14640372 | 0.37 |
ENST00000215567.5
ENST00000598298.1 ENST00000596073.1 ENST00000600083.1 ENST00000436007.2 |
TECR
|
trans-2,3-enoyl-CoA reductase |
| chr19_+_58341656 | 0.37 |
ENST00000442832.4
ENST00000594901.1 |
ZNF587B
|
zinc finger protein 587B |
| chr16_-_88729473 | 0.37 |
ENST00000301012.3
ENST00000569177.1 |
MVD
|
mevalonate (diphospho) decarboxylase |
| chr7_+_7196565 | 0.37 |
ENST00000429911.1
|
C1GALT1
|
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 |
| chrX_+_92929192 | 0.37 |
ENST00000332647.4
|
FAM133A
|
family with sequence similarity 133, member A |
| chr3_-_38835501 | 0.37 |
ENST00000449082.2
|
SCN10A
|
sodium channel, voltage-gated, type X, alpha subunit |
| chr2_+_27886330 | 0.36 |
ENST00000326019.6
|
SLC4A1AP
|
solute carrier family 4 (anion exchanger), member 1, adaptor protein |
| chr19_-_58400148 | 0.36 |
ENST00000595048.1
ENST00000600634.1 ENST00000595295.1 ENST00000596604.1 ENST00000597342.1 ENST00000597807.1 |
ZNF814
|
zinc finger protein 814 |
| chr11_-_34938039 | 0.36 |
ENST00000395787.3
|
APIP
|
APAF1 interacting protein |
| chr12_-_24097236 | 0.36 |
ENST00000538083.1
|
SOX5
|
SRY (sex determining region Y)-box 5 |
| chr3_+_161214596 | 0.35 |
ENST00000327928.4
|
OTOL1
|
otolin 1 |
| chrX_+_119737806 | 0.35 |
ENST00000371317.5
|
MCTS1
|
malignant T cell amplified sequence 1 |
| chr17_+_21030260 | 0.34 |
ENST00000579303.1
|
DHRS7B
|
dehydrogenase/reductase (SDR family) member 7B |
| chr15_+_74421961 | 0.34 |
ENST00000565159.1
ENST00000567206.1 |
ISLR2
|
immunoglobulin superfamily containing leucine-rich repeat 2 |
| chr4_-_113437328 | 0.34 |
ENST00000313341.3
|
NEUROG2
|
neurogenin 2 |
| chr4_+_120056939 | 0.33 |
ENST00000307128.5
|
MYOZ2
|
myozenin 2 |
| chr17_+_43239191 | 0.33 |
ENST00000589230.1
|
HEXIM2
|
hexamethylene bis-acetamide inducible 2 |
| chr16_-_20416053 | 0.33 |
ENST00000302451.4
|
PDILT
|
protein disulfide isomerase-like, testis expressed |
| chr5_-_86708670 | 0.33 |
ENST00000504878.1
|
CCNH
|
cyclin H |
| chr1_-_98511756 | 0.33 |
ENST00000602984.1
ENST00000602852.1 |
MIR137HG
|
MIR137 host gene (non-protein coding) |
| chr17_+_43239231 | 0.32 |
ENST00000591576.1
ENST00000591070.1 ENST00000592695.1 |
HEXIM2
|
hexamethylene bis-acetamide inducible 2 |
| chr22_+_31795509 | 0.32 |
ENST00000331457.4
|
DRG1
|
developmentally regulated GTP binding protein 1 |
| chr7_+_16700806 | 0.32 |
ENST00000446596.1
ENST00000438834.1 |
BZW2
|
basic leucine zipper and W2 domains 2 |
| chr16_-_70323422 | 0.32 |
ENST00000261772.8
|
AARS
|
alanyl-tRNA synthetase |
| chrX_-_70473957 | 0.31 |
ENST00000373984.3
ENST00000314425.5 ENST00000373982.1 |
ZMYM3
|
zinc finger, MYM-type 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PBX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 7.8 | GO:0003330 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 1.0 | 3.1 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 0.9 | 3.7 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 0.9 | 2.7 | GO:0070408 | carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718) |
| 0.8 | 2.5 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) |
| 0.8 | 2.4 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.7 | 2.2 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.6 | 2.6 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.6 | 1.8 | GO:0032824 | negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) |
| 0.5 | 7.6 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.5 | 1.6 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
| 0.5 | 11.6 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.4 | 2.4 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 0.4 | 2.6 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.3 | 1.8 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.3 | 2.4 | GO:0009753 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.3 | 1.9 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.2 | 4.6 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.2 | 0.9 | GO:0006781 | succinyl-CoA pathway(GO:0006781) |
| 0.2 | 1.5 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.2 | 3.6 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.2 | 3.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.2 | 1.3 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.2 | 1.8 | GO:2000467 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.2 | 1.2 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 2.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.2 | 5.1 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.1 | 0.5 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 0.1 | 0.4 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.1 | 0.8 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.1 | 0.3 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.1 | 0.6 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.1 | 0.6 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 0.9 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
| 0.1 | 0.5 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 1.0 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.1 | 3.4 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.1 | 0.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.1 | 0.8 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.1 | 0.4 | GO:0016267 | O-glycan processing, core 1(GO:0016267) |
| 0.1 | 1.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 4.2 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 1.6 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.1 | 1.7 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 0.3 | GO:1903939 | negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) |
| 0.1 | 1.1 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.1 | 1.5 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.1 | 0.6 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 1.6 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 1.5 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.1 | 0.6 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 0.1 | 6.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 1.6 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.5 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.2 | GO:0042245 | RNA repair(GO:0042245) |
| 0.1 | 1.7 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 1.2 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 0.6 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.1 | 0.3 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
| 0.1 | 0.7 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
| 0.1 | 0.7 | GO:0006538 | glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538) |
| 0.1 | 0.7 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.2 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
| 0.1 | 0.3 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.1 | 0.4 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.1 | 0.4 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.1 | 0.7 | GO:0009812 | flavonoid metabolic process(GO:0009812) |
| 0.1 | 2.1 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.0 | 0.8 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 1.0 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.0 | 0.2 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.0 | 0.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 2.0 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 1.0 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.0 | 0.9 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 1.0 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 1.4 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 0.3 | GO:0046836 | glycolipid transport(GO:0046836) |
| 0.0 | 0.4 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.0 | 0.3 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 0.0 | 0.3 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.0 | 0.4 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.0 | 1.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.8 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.0 | 0.6 | GO:1901661 | quinone metabolic process(GO:1901661) |
| 0.0 | 0.4 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.0 | 0.4 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.0 | 1.1 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.1 | GO:0080120 | CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120) |
| 0.0 | 1.1 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.0 | 0.2 | GO:0071233 | cellular response to leucine(GO:0071233) |
| 0.0 | 1.2 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 0.1 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
| 0.0 | 0.7 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 0.7 | GO:0016048 | detection of temperature stimulus(GO:0016048) |
| 0.0 | 0.7 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.0 | 0.4 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 1.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 0.3 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 0.3 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.0 | 0.5 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.1 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 0.0 | 1.5 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 0.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.0 | GO:0003147 | neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) |
| 0.0 | 0.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 0.2 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.2 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.0 | 0.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.6 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
| 0.0 | 0.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 4.6 | GO:0071062 | rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.2 | 1.8 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.2 | 3.6 | GO:0045179 | apical cortex(GO:0045179) |
| 0.2 | 0.7 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.2 | 1.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 2.0 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 0.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.1 | 1.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 0.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.1 | 1.0 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 4.2 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 9.6 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 0.4 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.1 | 0.6 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 0.2 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 0.5 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.1 | 0.8 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.1 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.0 | 0.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 0.3 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.0 | 2.7 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 5.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.1 | GO:0097196 | Shu complex(GO:0097196) |
| 0.0 | 0.5 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 0.6 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.6 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 0.7 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.9 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 4.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.0 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 1.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 1.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 3.4 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.7 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 9.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 2.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 3.5 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.2 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.1 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.0 | 0.3 | GO:0015935 | small ribosomal subunit(GO:0015935) |
| 0.0 | 17.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 1.6 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 2.0 | GO:0005884 | actin filament(GO:0005884) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.1 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 1.0 | 3.1 | GO:0052871 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 0.9 | 2.6 | GO:0008746 | NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652) |
| 0.8 | 2.5 | GO:0070546 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 0.7 | 2.7 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
| 0.5 | 3.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.5 | 1.5 | GO:0004397 | histidine ammonia-lyase activity(GO:0004397) |
| 0.5 | 7.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.5 | 2.4 | GO:0047023 | androsterone dehydrogenase activity(GO:0047023) |
| 0.5 | 1.8 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.4 | 3.2 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.4 | 1.5 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.3 | 0.7 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.3 | 1.0 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.3 | 15.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.2 | 0.9 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.2 | 2.5 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.2 | 8.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 1.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 0.9 | GO:0004775 | succinate-CoA ligase (ADP-forming) activity(GO:0004775) |
| 0.2 | 1.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.2 | 3.4 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 0.2 | 1.3 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.2 | 1.8 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.2 | 4.2 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.2 | 4.6 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.1 | 1.5 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 1.0 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.1 | 0.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.1 | 3.5 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 0.4 | GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) |
| 0.1 | 5.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 0.8 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 2.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.4 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.1 | 0.4 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.1 | 0.6 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.1 | 1.6 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.1 | 0.6 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.1 | 0.3 | GO:0051373 | FATZ binding(GO:0051373) |
| 0.1 | 1.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 0.4 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.1 | 2.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.2 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.1 | 0.2 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.0 | 1.1 | GO:0008392 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 2.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.7 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.7 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.3 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 1.8 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 1.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 1.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.0 | 1.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.2 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.0 | 1.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.7 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.0 | 0.5 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.0 | 0.3 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 0.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 1.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 0.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.1 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.0 | 0.1 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.1 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.0 | 1.8 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.4 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 1.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 3.9 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.3 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 1.0 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 8.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 3.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.1 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.0 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.7 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 14.7 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.2 | 3.4 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.2 | 2.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 3.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 3.5 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 3.1 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 1.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 5.1 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.4 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 1.8 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.1 | 2.3 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.1 | 5.9 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.1 | 1.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.0 | 1.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 2.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.2 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.3 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 1.0 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.3 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.7 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 0.8 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 6.7 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 2.1 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.0 | 1.0 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.0 | 4.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.5 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 1.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.2 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 0.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.8 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |