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Illumina Body Map 2, young vs old

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Results for PGR

Z-value: 0.29

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.10 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_1009998010.541.5e-03Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_54305101 4.23 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr4_-_88450612 3.94 ENST00000418378.1
ENST00000282470.6
SPARC-like 1 (hevin)
chr19_+_30863271 3.76 ENST00000355537.3
zinc finger protein 536
chr4_-_88450535 3.74 ENST00000541496.1
SPARC-like 1 (hevin)
chr4_-_88450372 3.48 ENST00000543631.1
SPARC-like 1 (hevin)
chr4_-_88450595 3.44 ENST00000434434.1
SPARC-like 1 (hevin)
chr20_-_52612705 3.37 ENST00000434986.2
breast carcinoma amplified sequence 1
chr4_-_88450511 3.34 ENST00000458304.2
SPARC-like 1 (hevin)
chr4_-_154710210 3.32 ENST00000274063.4
secreted frizzled-related protein 2
chr15_-_49255632 3.27 ENST00000332408.4
SHC (Src homology 2 domain containing) family, member 4
chr8_-_22089845 3.14 ENST00000454243.2
phytanoyl-CoA 2-hydroxylase interacting protein
chr20_-_52612468 3.02 ENST00000422805.1
breast carcinoma amplified sequence 1
chrX_-_132095419 2.99 ENST00000370836.2
ENST00000521489.1
heparan sulfate 6-O-sulfotransferase 2
chr12_-_88974236 2.78 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KIT ligand
chr10_-_49482907 2.61 ENST00000374201.3
ENST00000407470.4
FERM and PDZ domain containing 2
chr8_-_26371608 2.55 ENST00000522362.2
paraneoplastic Ma antigen 2
chr11_+_27062860 2.50 ENST00000528583.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_87028478 2.44 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr20_+_58203664 2.39 ENST00000541461.1
phosphatase and actin regulator 3
chr5_-_160279207 2.36 ENST00000327245.5
ATPase, class V, type 10B
chr3_-_139195350 2.25 ENST00000232217.2
retinol binding protein 2, cellular
chr8_+_35649365 2.20 ENST00000437887.1
Uncharacterized protein
chr2_+_73144604 2.18 ENST00000258106.6
empty spiracles homeobox 1
chrX_+_38420623 2.11 ENST00000378482.2
tetraspanin 7
chrX_-_21776281 2.08 ENST00000379494.3
small muscle protein, X-linked
chr17_-_42988004 2.07 ENST00000586125.1
ENST00000591880.1
glial fibrillary acidic protein
chr3_-_58563094 2.05 ENST00000464064.1
family with sequence similarity 107, member A
chr19_-_42947121 2.05 ENST00000601181.1
chemokine (C-X-C motif) ligand 17
chr12_-_71551652 2.03 ENST00000546561.1
tetraspanin 8
chr1_+_197237352 2.03 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr18_+_31185530 1.98 ENST00000586327.1
additional sex combs like 3 (Drosophila)
chr1_-_26394114 1.95 ENST00000374272.3
tripartite motif containing 63, E3 ubiquitin protein ligase
chr15_-_29745003 1.94 ENST00000560082.1
family with sequence similarity 189, member A1
chr18_+_580367 1.93 ENST00000327228.3
centrin, EF-hand protein, 1
chr2_-_183387064 1.88 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr15_+_48483736 1.88 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_+_16370271 1.83 ENST00000375679.4
chloride channel, voltage-sensitive Kb
chr15_-_65360276 1.81 ENST00000421977.3
RAS-like, family 12
chr2_-_175711978 1.79 ENST00000409089.2
chimerin 1
chr9_+_87285539 1.79 ENST00000359847.3
neurotrophic tyrosine kinase, receptor, type 2
chr9_+_127615733 1.77 ENST00000373574.1
WD repeat domain 38
chr18_-_44336998 1.76 ENST00000315087.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr13_+_102104980 1.75 ENST00000545560.2
integrin, beta-like 1 (with EGF-like repeat domains)
chr11_-_75379612 1.74 ENST00000526740.1
microtubule-associated protein 6
chr18_+_32173276 1.71 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr13_+_102104952 1.69 ENST00000376180.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr16_-_66952779 1.69 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr10_+_69865866 1.67 ENST00000354393.2
myopalladin
chrX_+_70364667 1.67 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
neuroligin 3
chr1_-_32210275 1.66 ENST00000440175.2
brain-specific angiogenesis inhibitor 2
chr14_+_29299437 1.65 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1
chr17_+_11144580 1.62 ENST00000441885.3
ENST00000432116.3
ENST00000409168.3
shisa family member 6
chr7_+_123241908 1.61 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chr5_+_140261703 1.60 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr20_+_33589048 1.59 ENST00000446156.1
ENST00000453028.1
ENST00000435272.1
ENST00000433934.2
ENST00000456649.1
myosin, heavy chain 7B, cardiac muscle, beta
chr19_-_36247910 1.59 ENST00000587965.1
ENST00000004982.3
heat shock protein, alpha-crystallin-related, B6
chr10_+_68685764 1.58 ENST00000361320.4
leucine rich repeat transmembrane neuronal 3
chr3_+_125985620 1.56 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
chr9_+_1051481 1.56 ENST00000358146.2
ENST00000259622.6
doublesex and mab-3 related transcription factor 2
chr17_+_37824411 1.55 ENST00000269582.2
phenylethanolamine N-methyltransferase
chr2_-_175711924 1.54 ENST00000444573.1
chimerin 1
chr3_+_158991025 1.53 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr16_+_58497274 1.52 ENST00000564207.1
NDRG family member 4
chrX_-_114253536 1.52 ENST00000371936.1
interleukin 13 receptor, alpha 2
chr16_-_66952742 1.52 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr6_+_72926145 1.51 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr15_-_76005170 1.50 ENST00000308508.5
chondroitin sulfate proteoglycan 4
chr4_-_87770416 1.50 ENST00000273905.6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr5_-_121413974 1.50 ENST00000231004.4
lysyl oxidase
chr4_+_79567233 1.49 ENST00000514130.1
long intergenic non-protein coding RNA 1094
chr11_-_75379479 1.48 ENST00000434603.2
microtubule-associated protein 6
chr8_-_11325047 1.48 ENST00000531804.1
family with sequence similarity 167, member A
chr6_-_47010061 1.46 ENST00000371253.2
G protein-coupled receptor 110
chr2_-_183387283 1.46 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr2_-_183387430 1.45 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr1_+_178482212 1.45 ENST00000319416.2
ENST00000258298.2
ENST00000367643.3
ENST00000367642.3
testis expressed 35
chr15_-_58306295 1.44 ENST00000559517.1
aldehyde dehydrogenase 1 family, member A2
chr1_-_166944652 1.44 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
immunoglobulin-like domain containing receptor 2
chr8_+_70476088 1.44 ENST00000525999.1
sulfatase 1
chr2_-_158182410 1.43 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr3_-_149051194 1.43 ENST00000470080.1
transmembrane 4 L six family member 18
chr11_-_126810521 1.42 ENST00000530572.1
RP11-688I9.4
chr4_-_139163491 1.42 ENST00000280612.5
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_-_205391178 1.37 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr3_+_173113898 1.37 ENST00000423427.1
neuroligin 1
chr18_-_3880051 1.37 ENST00000584874.1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_158182322 1.36 ENST00000420719.2
ENST00000409216.1
ermin, ERM-like protein
chr2_-_134326009 1.36 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr2_+_48796120 1.36 ENST00000394754.1
STON1-GTF2A1L readthrough
chr1_-_166944561 1.35 ENST00000271417.3
immunoglobulin-like domain containing receptor 2
chr9_-_73736511 1.35 ENST00000377110.3
ENST00000377111.2
transient receptor potential cation channel, subfamily M, member 3
chr1_+_95286151 1.35 ENST00000467909.1
ENST00000422520.2
ENST00000532427.1
solute carrier family 44, member 3
chr13_-_45768841 1.34 ENST00000379108.1
potassium channel tetramerization domain containing 4
chr17_+_37824217 1.33 ENST00000394246.1
phenylethanolamine N-methyltransferase
chrX_+_134887233 1.33 ENST00000443882.1
cancer/testis antigen family 45, member A3
chr11_-_88796803 1.32 ENST00000418177.2
ENST00000455756.2
glutamate receptor, metabotropic 5
chrX_+_135570046 1.31 ENST00000370648.3
bombesin-like receptor 3
chr2_+_232135245 1.31 ENST00000446447.1
armadillo repeat containing 9
chr5_+_140797296 1.30 ENST00000398594.2
protocadherin gamma subfamily B, 7
chr10_-_118429461 1.30 ENST00000588184.1
ENST00000369210.3
chromosome 10 open reading frame 82
chr6_+_30852738 1.29 ENST00000508312.1
ENST00000512336.1
discoidin domain receptor tyrosine kinase 1
chr12_+_79258547 1.29 ENST00000457153.2
synaptotagmin I
chr16_+_86600857 1.28 ENST00000320354.4
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr4_-_90759440 1.28 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_19144243 1.28 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr15_-_88799661 1.27 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
neurotrophic tyrosine kinase, receptor, type 3
chr6_+_30853002 1.26 ENST00000421124.2
ENST00000512725.1
discoidin domain receptor tyrosine kinase 1
chr14_-_23876801 1.26 ENST00000356287.3
myosin, heavy chain 6, cardiac muscle, alpha
chr1_-_234667504 1.26 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr17_+_65027509 1.25 ENST00000375684.1
Uncharacterized protein
chr9_-_34665983 1.25 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr7_+_30960915 1.25 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
aquaporin 1 (Colton blood group)
chr2_-_175711133 1.25 ENST00000409597.1
ENST00000413882.1
chimerin 1
chr11_-_26744908 1.24 ENST00000533617.1
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr12_+_58003935 1.24 ENST00000333972.7
Rho guanine nucleotide exchange factor (GEF) 25
chr2_-_180427304 1.22 ENST00000336917.5
zinc finger protein 385B
chr6_+_74405501 1.22 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr15_-_88799384 1.22 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
neurotrophic tyrosine kinase, receptor, type 3
chr2_-_183106641 1.21 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr5_+_180650271 1.21 ENST00000351937.5
ENST00000315073.5
tripartite motif containing 41
chr8_-_52721975 1.21 ENST00000356297.4
ENST00000543296.1
peroxidasin homolog (Drosophila)-like
chr3_-_179754806 1.21 ENST00000485199.1
peroxisomal biogenesis factor 5-like
chr17_-_15168624 1.21 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
peripheral myelin protein 22
chr1_+_162335197 1.21 ENST00000431696.1
Uncharacterized protein
chr1_-_145039835 1.20 ENST00000533259.1
phosphodiesterase 4D interacting protein
chr6_-_46922659 1.20 ENST00000265417.7
G protein-coupled receptor 116
chr10_+_97709725 1.20 ENST00000472454.2
Protein LOC100652732
chr3_-_179754556 1.18 ENST00000263962.8
peroxisomal biogenesis factor 5-like
chr13_-_103053946 1.17 ENST00000376131.4
fibroblast growth factor 14
chr19_+_46806856 1.16 ENST00000300862.3
hypoxia inducible factor 3, alpha subunit
chr1_+_172422026 1.16 ENST00000367725.4
chromosome 1 open reading frame 105
chr20_-_44168046 1.14 ENST00000372665.3
ENST00000372670.3
ENST00000600168.1
WAP four-disulfide core domain 6
chr7_-_92855762 1.13 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr17_+_59477233 1.13 ENST00000240328.3
T-box 2
chr3_-_48057890 1.13 ENST00000434267.1
microtubule-associated protein 4
chr6_+_108487245 1.13 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr2_+_173686303 1.13 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr3_-_149051444 1.12 ENST00000296059.2
transmembrane 4 L six family member 18
chr1_-_201391149 1.12 ENST00000555948.1
ENST00000556362.1
troponin I type 1 (skeletal, slow)
chr4_+_128802016 1.11 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chr12_-_81763184 1.09 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr18_+_43307294 1.07 ENST00000590246.1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr1_-_112903150 1.07 ENST00000427290.1
RP5-965F6.2
chr7_+_99202003 1.06 ENST00000609449.1
GS1-259H13.2
chr1_-_156828810 1.06 ENST00000368195.3
insulin receptor-related receptor
chr6_+_74405804 1.05 ENST00000287097.5
CD109 molecule
chr5_+_102201430 1.04 ENST00000438793.3
ENST00000346918.2
peptidylglycine alpha-amidating monooxygenase
chr3_-_179754733 1.03 ENST00000472994.1
peroxisomal biogenesis factor 5-like
chr16_-_3350614 1.03 ENST00000268674.2
tigger transposable element derived 7
chr17_+_7308172 1.02 ENST00000575301.1
neuroligin 2
chr9_-_140196703 1.01 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr5_+_137419581 1.01 ENST00000506684.1
ENST00000504809.1
ENST00000398754.1
wingless-type MMTV integration site family, member 8A
chr19_+_51153045 1.00 ENST00000458538.1
chromosome 19 open reading frame 81
chr7_-_123673471 0.99 ENST00000455783.1
transmembrane protein 229A
chr17_+_67590125 0.98 ENST00000591334.1
AC003051.1
chr7_+_105603738 0.98 ENST00000541203.1
cadherin-related family member 3
chr3_+_147795932 0.97 ENST00000490465.1
RP11-639B1.1
chr5_-_179107975 0.97 ENST00000376974.4
chibby homolog 3 (Drosophila)
chr3_-_114343039 0.97 ENST00000481632.1
zinc finger and BTB domain containing 20
chr12_+_40549984 0.96 ENST00000457989.1
AC079630.2
chr7_+_73442487 0.96 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
elastin
chr16_-_54882145 0.96 ENST00000561591.1
RP11-1136G4.1
chr2_-_167350747 0.96 ENST00000419992.1
sodium channel, voltage-gated, type VII, alpha subunit
chr7_+_105603683 0.95 ENST00000317716.9
cadherin-related family member 3
chr3_-_179754706 0.95 ENST00000465751.1
ENST00000467460.1
peroxisomal biogenesis factor 5-like
chr1_-_145039771 0.94 ENST00000493130.2
ENST00000532801.1
ENST00000478649.2
phosphodiesterase 4D interacting protein
chr14_-_21056121 0.94 ENST00000557105.1
ENST00000398008.2
ENST00000555841.1
ENST00000443456.2
ENST00000432835.2
ENST00000557503.1
ENST00000398009.2
ENST00000554842.1
ribonuclease, RNase A family, 11 (non-active)
chr5_-_38557561 0.94 ENST00000511561.1
leukemia inhibitory factor receptor alpha
chr7_+_79763271 0.93 ENST00000442586.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr19_+_42254885 0.93 ENST00000595740.1
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr1_-_61719160 0.93 ENST00000442027.1
ENST00000596354.1
ENST00000596404.1
RP5-833A20.1
chr11_+_125034640 0.92 ENST00000542175.1
PBX/knotted 1 homeobox 2
chr16_+_202686 0.92 ENST00000252951.2
hemoglobin, zeta
chr1_+_111770278 0.91 ENST00000369748.4
chitinase 3-like 2
chr12_-_11422630 0.91 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr8_+_142524738 0.91 ENST00000427937.1
Uncharacterized protein
chr8_-_87755878 0.91 ENST00000320005.5
cyclic nucleotide gated channel beta 3
chr10_-_97200772 0.91 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr7_-_14026123 0.90 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chr1_+_178482262 0.90 ENST00000367641.3
ENST00000367639.1
testis expressed 35
chr6_-_76203454 0.90 ENST00000237172.7
filamin A interacting protein 1
chr1_-_110933663 0.89 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
solute carrier family 16, member 4
chr2_+_111562758 0.89 ENST00000433706.1
acyl-CoA oxidase-like
chr5_+_72469014 0.89 ENST00000296776.5
transmembrane protein 174
chr1_-_145039949 0.89 ENST00000313382.9
phosphodiesterase 4D interacting protein
chr1_+_111770232 0.88 ENST00000369744.2
chitinase 3-like 2
chrX_+_101478829 0.88 ENST00000372763.1
ENST00000372758.1
nuclear RNA export factor 2
chr11_-_62689046 0.88 ENST00000306960.3
ENST00000543973.1
cholinergic receptor, muscarinic 1
chr3_+_25469802 0.88 ENST00000330688.4
retinoic acid receptor, beta
chrX_+_109602039 0.87 ENST00000520821.1
retrotransposon gag domain containing 1
chr2_-_216300784 0.87 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
fibronectin 1
chr6_-_150212029 0.87 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
retinoic acid early transcript 1E
chr17_-_46691990 0.86 ENST00000576562.1
homeobox B8
chr18_+_43304092 0.86 ENST00000321925.4
ENST00000587601.1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr2_-_158182105 0.86 ENST00000409925.1
ermin, ERM-like protein
chr8_+_65285851 0.85 ENST00000520799.1
ENST00000521441.1
long intergenic non-protein coding RNA 966
chr18_+_6729725 0.84 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
Rho GTPase activating protein 28
chr7_+_105603699 0.84 ENST00000478080.1
cadherin-related family member 3
chr4_+_100432161 0.83 ENST00000326581.4
ENST00000514652.1
chromosome 4 open reading frame 17
chr1_-_85870177 0.82 ENST00000542148.1
dimethylarginine dimethylaminohydrolase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.9 2.8 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.7 2.9 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.6 2.5 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.5 1.0 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.5 3.0 GO:0018032 protein amidation(GO:0018032)
0.5 3.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.3 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.4 4.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.4 1.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.4 4.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 2.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.4 1.1 GO:1901207 mammary placode formation(GO:0060596) regulation of heart looping(GO:1901207)
0.4 4.1 GO:0072553 terminal button organization(GO:0072553)
0.3 1.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 1.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.3 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 6.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.8 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3 2.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 0.9 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.3 2.3 GO:0072675 osteoclast fusion(GO:0072675)
0.3 1.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.1 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.3 2.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 1.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.3 1.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.3 0.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.3 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.7 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2 1.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 3.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 3.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 2.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 2.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 4.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 1.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 2.0 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 0.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.4 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 3.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 2.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 0.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.9 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.5 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 1.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 4.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 2.0 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 1.3 GO:0015871 choline transport(GO:0015871)
0.1 1.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 1.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 1.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.5 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 1.1 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 2.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.8 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 1.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.9 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 1.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 1.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.6 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 1.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 1.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.5 GO:0030238 male sex determination(GO:0030238)
0.0 1.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 1.6 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 8.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.5 GO:1902969 mitotic DNA replication(GO:1902969)
0.0 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 1.5 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.9 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.5 GO:0015747 urate transport(GO:0015747)
0.0 2.6 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 1.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.7 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 1.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.9 GO:0030252 growth hormone secretion(GO:0030252)
0.0 17.1 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.9 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.6 GO:0001501 skeletal system development(GO:0001501)
0.0 0.4 GO:0038084 vascular endothelial growth factor signaling pathway(GO:0038084)
0.0 0.0 GO:0061551 trigeminal ganglion development(GO:0061551) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.2 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.7 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.8 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.8 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0044305 calyx of Held(GO:0044305)
0.4 1.2 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3 2.1 GO:0005927 muscle tendon junction(GO:0005927)
0.3 0.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.3 3.6 GO:0033269 internode region of axon(GO:0033269)
0.2 2.6 GO:0071953 elastic fiber(GO:0071953)
0.2 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.1 GO:0098536 deuterosome(GO:0098536)
0.2 1.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0000811 GINS complex(GO:0000811)
0.1 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.0 GO:0042025 host cell nucleus(GO:0042025)
0.1 0.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 3.5 GO:0032982 myosin filament(GO:0032982)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 3.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0097386 voltage-gated sodium channel complex(GO:0001518) glial cell projection(GO:0097386)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.0 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0043218 compact myelin(GO:0043218)
0.0 1.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 4.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.0 15.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0031672 A band(GO:0031672)
0.0 0.8 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 7.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 6.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.0 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.0 3.9 GO:0030016 myofibril(GO:0030016)
0.0 6.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 4.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.9 GO:0043235 receptor complex(GO:0043235)
0.0 2.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.9 6.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.7 3.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.7 2.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 1.9 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.6 2.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.5 3.0 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 4.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 1.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.4 1.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.4 3.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 3.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.8 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 1.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 2.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 1.9 GO:0015265 urea channel activity(GO:0015265)
0.3 1.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 3.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.9 GO:0017018 myosin phosphatase activity(GO:0017018)
0.2 2.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.9 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 4.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 14.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.7 GO:0016918 retinal binding(GO:0016918)
0.1 1.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.9 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 4.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.8 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.8 GO:0004568 chitinase activity(GO:0004568)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 2.1 GO:0031432 titin binding(GO:0031432)
0.1 1.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 2.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 2.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 2.0 GO:0022839 ion gated channel activity(GO:0022839)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742) phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.4 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.0 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 19.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 3.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 2.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes