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Illumina Body Map 2, young vs old

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Results for PKNOX2

Z-value: 0.06

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Transcription factors associated with PKNOX2

Gene Symbol Gene ID Gene Info
PKNOX2
ENSG00000165495.11 PBX/knotted 1 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PKNOX2hg19_v2_chr11_+_125034605_1250346360.144.6e-01Click!

Activity profile of PKNOX2 motif

Sorted Z-values of PKNOX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_31674639 0.85 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr21_-_34185989 0.68 ENST00000487113.1
ENST00000382373.4
C21orf62
chromosome 21 open reading frame 62
chr1_-_201081579 0.63 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr21_-_34185944 0.59 ENST00000479548.1
C21orf62
chromosome 21 open reading frame 62
chr2_-_211179883 0.59 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr14_+_22958441 0.58 ENST00000390488.1
TRAJ49
T cell receptor alpha joining 49
chr5_-_58882219 0.57 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_-_42452063 0.57 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr2_+_113321939 0.53 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr21_-_34186006 0.52 ENST00000490358.1
C21orf62
chromosome 21 open reading frame 62
chr17_-_29151686 0.48 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr17_-_29151794 0.48 ENST00000324238.6
CRLF3
cytokine receptor-like factor 3
chrX_-_153095813 0.45 ENST00000544474.1
PDZD4
PDZ domain containing 4
chr21_-_32931290 0.44 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr14_-_21994337 0.43 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr1_+_66258846 0.43 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr18_+_54318566 0.42 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr11_-_71810258 0.42 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr6_-_114664180 0.41 ENST00000312719.5
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr8_+_11666649 0.41 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr14_-_21994525 0.40 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr9_-_132805430 0.39 ENST00000446176.2
ENST00000355681.3
ENST00000420781.1
FNBP1
formin binding protein 1
chrX_-_39923656 0.38 ENST00000413905.1
BCOR
BCL6 corepressor
chr6_-_84418841 0.38 ENST00000369694.2
ENST00000195649.6
SNAP91
synaptosomal-associated protein, 91kDa
chr9_-_79307096 0.37 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2
prune homolog 2 (Drosophila)
chr18_+_54318616 0.36 ENST00000254442.3
WDR7
WD repeat domain 7
chr7_-_100253993 0.36 ENST00000461605.1
ENST00000160382.5
ACTL6B
actin-like 6B
chr6_-_84418860 0.36 ENST00000521743.1
SNAP91
synaptosomal-associated protein, 91kDa
chr5_-_139283982 0.33 ENST00000340391.3
NRG2
neuregulin 2
chr5_-_132073111 0.33 ENST00000403231.1
KIF3A
kinesin family member 3A
chr22_-_31885514 0.33 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_-_247171347 0.32 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chrX_-_153775426 0.31 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr18_+_54318893 0.30 ENST00000593058.1
WDR7
WD repeat domain 7
chrX_-_77225135 0.29 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr22_+_20905269 0.29 ENST00000457322.1
MED15
mediator complex subunit 15
chr1_-_54872059 0.29 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr1_+_161736072 0.28 ENST00000367942.3
ATF6
activating transcription factor 6
chr1_+_145549203 0.28 ENST00000355594.4
ENST00000544626.1
ANKRD35
ankyrin repeat domain 35
chr6_+_24126350 0.28 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr2_-_74780176 0.27 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr18_+_3449330 0.27 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr3_-_101395936 0.27 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr4_-_46391805 0.27 ENST00000540012.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_+_26124373 0.26 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr17_+_8316442 0.26 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr12_-_62653903 0.26 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr2_-_219524193 0.26 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chr3_+_140981456 0.25 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr11_+_12132117 0.25 ENST00000256194.4
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr15_+_34260921 0.25 ENST00000560035.1
CHRM5
cholinergic receptor, muscarinic 5
chr6_-_101329191 0.25 ENST00000324723.6
ENST00000369162.2
ENST00000522650.1
ASCC3
activating signal cointegrator 1 complex subunit 3
chr17_+_38474489 0.25 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr1_-_179112173 0.24 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_-_72358001 0.24 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr2_-_242842587 0.24 ENST00000404031.1
AC131097.4
Protein LOC285095
chr22_+_20905286 0.23 ENST00000428629.1
MED15
mediator complex subunit 15
chr7_-_156803329 0.23 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr9_-_123639600 0.23 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_-_179112189 0.23 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr15_-_61521495 0.22 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr11_-_46867780 0.22 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr6_-_32140886 0.22 ENST00000395496.1
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr17_+_78518617 0.22 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr11_-_132812987 0.22 ENST00000541867.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr6_-_84418738 0.22 ENST00000519779.1
SNAP91
synaptosomal-associated protein, 91kDa
chr4_-_46391567 0.21 ENST00000507460.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr22_+_20905422 0.21 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr3_+_46742823 0.21 ENST00000326431.3
TMIE
transmembrane inner ear
chr1_+_181057638 0.21 ENST00000367577.4
IER5
immediate early response 5
chr17_-_4046257 0.21 ENST00000381638.2
ZZEF1
zinc finger, ZZ-type with EF-hand domain 1
chr6_+_37225540 0.20 ENST00000373491.3
TBC1D22B
TBC1 domain family, member 22B
chr2_-_74779744 0.20 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr7_-_104909435 0.20 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr6_-_84418432 0.20 ENST00000519825.1
ENST00000523484.2
SNAP91
synaptosomal-associated protein, 91kDa
chr19_+_57050317 0.20 ENST00000301318.3
ENST00000591844.1
ZFP28
ZFP28 zinc finger protein
chr3_-_52001448 0.20 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
PCBP4
poly(rC) binding protein 4
chr19_-_6424783 0.20 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr1_-_35658736 0.20 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr8_+_31496809 0.20 ENST00000518104.1
ENST00000519301.1
NRG1
neuregulin 1
chr12_-_121734489 0.19 ENST00000412367.2
ENST00000402834.4
ENST00000404169.3
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr11_-_132813566 0.19 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr17_-_26220366 0.19 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr6_-_101329157 0.19 ENST00000369143.2
ASCC3
activating signal cointegrator 1 complex subunit 3
chr19_+_36142147 0.19 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr22_+_17082732 0.18 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr16_-_1275257 0.18 ENST00000234798.4
TPSG1
tryptase gamma 1
chr10_+_94608245 0.17 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr13_+_33160553 0.17 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_-_61765732 0.16 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_+_113033164 0.16 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr18_-_67872891 0.15 ENST00000454359.1
ENST00000437017.1
RTTN
rotatin
chr16_-_3030407 0.15 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
PKMYT1
protein kinase, membrane associated tyrosine/threonine 1
chr5_-_127873896 0.15 ENST00000502468.1
FBN2
fibrillin 2
chr17_-_35969409 0.14 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chrX_+_41548220 0.14 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr4_-_149365827 0.14 ENST00000344721.4
NR3C2
nuclear receptor subfamily 3, group C, member 2
chr6_+_110299501 0.14 ENST00000414000.2
GPR6
G protein-coupled receptor 6
chr12_+_69201923 0.14 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr15_+_96904487 0.14 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr16_+_50776021 0.14 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr10_+_28822636 0.14 ENST00000442148.1
ENST00000448193.1
WAC
WW domain containing adaptor with coiled-coil
chr15_+_59908633 0.13 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_113263199 0.13 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr9_-_123639304 0.13 ENST00000436309.1
PHF19
PHD finger protein 19
chr20_+_43514320 0.13 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr4_-_46391367 0.13 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_+_22778337 0.13 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr22_+_30279144 0.13 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3
myotubularin related protein 3
chr11_-_132813627 0.13 ENST00000374778.4
OPCML
opioid binding protein/cell adhesion molecule-like
chr4_-_157892055 0.13 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr3_-_52719810 0.12 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr6_+_108881012 0.12 ENST00000343882.6
FOXO3
forkhead box O3
chr22_-_30234218 0.12 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr11_-_1782625 0.12 ENST00000438213.1
CTSD
cathepsin D
chr9_-_99637820 0.12 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr3_-_3221358 0.12 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr18_+_30349623 0.12 ENST00000426194.1
AC012123.1
Uncharacterized protein
chr2_-_61765315 0.11 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr4_+_3076388 0.11 ENST00000355072.5
HTT
huntingtin
chr17_+_39868577 0.11 ENST00000329402.3
GAST
gastrin
chr6_+_29910301 0.11 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr6_+_138188551 0.11 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_-_30457048 0.11 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr19_+_10828724 0.11 ENST00000585892.1
ENST00000314646.5
ENST00000359692.6
DNM2
dynamin 2
chr5_-_81046922 0.11 ENST00000514493.1
ENST00000320672.4
SSBP2
single-stranded DNA binding protein 2
chr2_-_190446738 0.11 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr10_+_70661014 0.11 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chrX_+_41548259 0.11 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr17_-_27405875 0.11 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr6_+_150070831 0.10 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_42123141 0.10 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr6_-_149867122 0.10 ENST00000253329.2
PPIL4
peptidylprolyl isomerase (cyclophilin)-like 4
chr5_-_81046841 0.10 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr1_-_100598444 0.09 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr6_+_150070857 0.09 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_-_74660159 0.08 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr14_-_69619689 0.08 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr19_+_10828795 0.08 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
DNM2
dynamin 2
chrX_+_2924654 0.08 ENST00000381130.2
ARSH
arylsulfatase family, member H
chr2_+_64681219 0.08 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr9_-_73477826 0.08 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr11_-_111741994 0.07 ENST00000398006.2
ALG9
ALG9, alpha-1,2-mannosyltransferase
chr16_+_19297047 0.07 ENST00000493231.1
CLEC19A
C-type lectin domain family 19, member A
chr11_-_83878041 0.07 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr22_+_50946645 0.07 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
NCAPH2
non-SMC condensin II complex, subunit H2
chr15_+_68346501 0.07 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr10_+_51565188 0.07 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr1_-_234667504 0.07 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr6_-_29324054 0.06 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr4_+_140222609 0.06 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_119247004 0.06 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr2_+_64681103 0.06 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr21_-_26797019 0.06 ENST00000440205.1
LINC00158
long intergenic non-protein coding RNA 158
chr18_+_3450161 0.05 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr5_-_81046904 0.05 ENST00000515395.1
SSBP2
single-stranded DNA binding protein 2
chr9_-_140142181 0.05 ENST00000484720.1
FAM166A
family with sequence similarity 166, member A
chr12_+_62654155 0.05 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr16_+_88636789 0.05 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18
chr5_-_94620239 0.04 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr18_-_54318353 0.04 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr3_-_52719912 0.04 ENST00000420148.1
PBRM1
polybromo 1
chr6_+_138188378 0.04 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_+_62654119 0.04 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr11_-_74660065 0.04 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr10_+_94608218 0.04 ENST00000371543.1
EXOC6
exocyst complex component 6
chr3_+_183899770 0.03 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr9_-_123639445 0.03 ENST00000312189.6
PHF19
PHD finger protein 19
chr1_-_179198702 0.03 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr2_+_219081817 0.03 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr3_+_113667354 0.03 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr4_-_100871506 0.03 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr7_+_1272522 0.03 ENST00000316333.8
UNCX
UNC homeobox
chr8_+_133787586 0.03 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr18_-_44775554 0.03 ENST00000425639.1
ENST00000400404.1
SKOR2
SKI family transcriptional corepressor 2
chr9_+_125027127 0.03 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr14_+_61995722 0.02 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr4_-_157892167 0.02 ENST00000541126.1
PDGFC
platelet derived growth factor C
chr19_-_39735646 0.02 ENST00000413851.2
IFNL3
interferon, lambda 3
chr10_+_49514698 0.02 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr20_-_31124186 0.02 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr22_-_50946113 0.01 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
LMF2
lipase maturation factor 2
chr2_+_219524473 0.01 ENST00000439945.1
ENST00000431802.1
BCS1L
BC1 (ubiquinol-cytochrome c reductase) synthesis-like
chr17_+_68071458 0.01 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr3_+_23244579 0.01 ENST00000452894.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr19_+_39759154 0.01 ENST00000331982.5
IFNL2
interferon, lambda 2
chr16_-_57481278 0.01 ENST00000567751.1
ENST00000568940.1
ENST00000563341.1
ENST00000565961.1
ENST00000569370.1
ENST00000567518.1
ENST00000565786.1
ENST00000394391.4
CIAPIN1
cytokine induced apoptosis inhibitor 1
chr5_+_118406796 0.01 ENST00000503802.1
DMXL1
Dmx-like 1
chr10_-_124768300 0.01 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr18_+_3449695 0.00 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr3_+_23244780 0.00 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr8_-_57123815 0.00 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.1 0.4 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.6 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.1 GO:1903980 positive regulation of microglial cell activation(GO:1903980)
0.0 0.5 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.0 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.4 GO:0050656 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway