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Illumina Body Map 2, young vs old

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Results for PLAG1

Z-value: 0.18

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Transcription factors associated with PLAG1

Gene Symbol Gene ID Gene Info
ENSG00000181690.3 PLAG1 zinc finger

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PLAG1hg19_v2_chr8_-_57123815_571238670.431.4e-02Click!

Activity profile of PLAG1 motif

Sorted Z-values of PLAG1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_220306745 2.37 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG complex locus
chr17_+_30593195 1.92 ENST00000431505.2
ENST00000269051.4
ENST00000538145.1
rhomboid, veinlet-like 3 (Drosophila)
chr15_-_44486632 1.62 ENST00000484674.1
FERM domain containing 5
chr9_+_139874683 1.54 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chr11_+_46299199 1.51 ENST00000529193.1
ENST00000288400.3
cAMP responsive element binding protein 3-like 1
chr19_+_55795493 1.47 ENST00000309383.1
BR serine/threonine kinase 1
chr14_-_25519317 1.40 ENST00000323944.5
syntaxin binding protein 6 (amisyn)
chr14_-_25519095 1.40 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
syntaxin binding protein 6 (amisyn)
chr1_-_31845914 1.40 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr16_-_65155833 1.31 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_58005204 1.30 ENST00000286494.4
Rho guanine nucleotide exchange factor (GEF) 25
chr14_+_79746249 1.28 ENST00000428277.2
neurexin 3
chrX_-_45060135 1.27 ENST00000398000.2
ENST00000377934.4
chromosome X open reading frame 36
chr5_+_7654057 1.25 ENST00000537121.1
adenylate cyclase 2 (brain)
chr3_-_73673991 1.24 ENST00000308537.4
ENST00000263666.4
PDZ domain containing ring finger 3
chr11_+_1940925 1.23 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr14_+_79745746 1.18 ENST00000281127.7
neurexin 3
chr1_-_201438282 1.17 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr18_+_56531584 1.16 ENST00000590287.1
zinc finger protein 532
chr14_+_79745682 1.14 ENST00000557594.1
neurexin 3
chr3_-_116163830 1.10 ENST00000333617.4
limbic system-associated membrane protein
chr1_+_163038565 1.03 ENST00000421743.2
regulator of G-protein signaling 4
chr19_-_35626104 1.01 ENST00000310123.3
ENST00000392225.3
leucine-rich repeat LGI family, member 4
chr17_+_45771420 0.99 ENST00000578982.1
TBK1 binding protein 1
chr19_-_49565254 0.93 ENST00000593537.1
neurotrophin 4
chr11_-_1606513 0.89 ENST00000382171.2
keratin associated protein 5-1
chr2_-_74618907 0.89 ENST00000421392.1
ENST00000437375.1
dynactin 1
chr9_+_2621950 0.89 ENST00000382096.1
very low density lipoprotein receptor
chrX_-_78622805 0.89 ENST00000373298.2
integral membrane protein 2A
chr19_+_40973049 0.87 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
spectrin, beta, non-erythrocytic 4
chr1_+_202431859 0.85 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chrX_+_51927919 0.81 ENST00000416960.1
melanoma antigen family D, 4
chr11_-_2323290 0.79 ENST00000381153.3
chromosome 11 open reading frame 21
chr19_-_51054299 0.79 ENST00000599957.1
leucine rich repeat containing 4B
chr17_+_39968926 0.79 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FK506 binding protein 10, 65 kDa
chr12_+_122018697 0.75 ENST00000541574.1
RP13-941N14.1
chr4_-_5890145 0.74 ENST00000397890.2
collapsin response mediator protein 1
chr12_+_79258444 0.73 ENST00000261205.4
synaptotagmin I
chr1_+_145470504 0.72 ENST00000323397.4
ankyrin repeat domain 34A
chr7_-_158380371 0.72 ENST00000389418.4
ENST00000389416.4
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr14_-_75079294 0.71 ENST00000556359.1
latent transforming growth factor beta binding protein 2
chr9_-_34662651 0.70 ENST00000259631.4
chemokine (C-C motif) ligand 27
chr14_-_75079026 0.70 ENST00000261978.4
latent transforming growth factor beta binding protein 2
chr22_+_19744226 0.69 ENST00000332710.4
ENST00000329705.7
ENST00000359500.3
T-box 1
chr11_-_6440283 0.67 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr11_-_45687128 0.66 ENST00000308064.2
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr1_-_115632035 0.65 ENST00000433172.1
ENST00000369514.2
ENST00000369516.2
ENST00000369515.2
tetraspanin 2
chr19_+_40697514 0.63 ENST00000253055.3
mitogen-activated protein kinase kinase kinase 10
chr7_-_158380465 0.62 ENST00000389413.3
ENST00000409483.1
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr4_+_36283213 0.60 ENST00000357504.3
death domain containing 1
chrX_-_16887963 0.58 ENST00000380084.4
retinoblastoma binding protein 7
chr1_-_151138422 0.57 ENST00000440902.2
LysM, putative peptidoglycan-binding, domain containing 1
chr8_-_23261589 0.57 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr11_+_1651033 0.54 ENST00000399676.2
keratin associated protein 5-5
chr12_-_58131931 0.54 ENST00000547588.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr12_+_57998595 0.54 ENST00000337737.3
ENST00000548198.1
ENST00000551632.1
deltex homolog 3 (Drosophila)
chr9_+_2621798 0.54 ENST00000382100.3
very low density lipoprotein receptor
chr2_+_153191706 0.53 ENST00000288670.9
formin-like 2
chr2_-_74618964 0.51 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr11_-_94964210 0.51 ENST00000416495.2
ENST00000393234.1
sestrin 3
chr19_-_2702681 0.50 ENST00000382159.3
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_4607335 0.49 ENST00000570571.1
ENST00000575101.1
ENST00000436683.2
ENST00000574876.1
proline, glutamate and leucine rich protein 1
chr2_-_30144432 0.48 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr5_+_161274940 0.48 ENST00000393943.4
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_+_57998400 0.48 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
deltex homolog 3 (Drosophila)
chrX_-_137793826 0.48 ENST00000315930.6
fibroblast growth factor 13
chr5_+_161275320 0.47 ENST00000437025.2
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr7_+_73703728 0.46 ENST00000361545.5
ENST00000223398.6
CAP-GLY domain containing linker protein 2
chr1_-_151138323 0.46 ENST00000368908.5
LysM, putative peptidoglycan-binding, domain containing 1
chr20_+_35169885 0.46 ENST00000279022.2
ENST00000346786.2
myosin, light chain 9, regulatory
chr12_+_79258547 0.45 ENST00000457153.2
synaptotagmin I
chr3_-_19988462 0.45 ENST00000344838.4
EF-hand domain family, member B
chr6_-_33285505 0.44 ENST00000431845.2
zinc finger and BTB domain containing 22
chr20_-_1974692 0.44 ENST00000217305.2
ENST00000539905.1
prodynorphin
chr15_+_29131103 0.44 ENST00000558402.1
ENST00000558330.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr19_+_38924316 0.43 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
ryanodine receptor 1 (skeletal)
chr2_+_157292933 0.43 ENST00000540309.1
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr4_-_114682719 0.41 ENST00000394522.3
calcium/calmodulin-dependent protein kinase II delta
chr11_-_94964354 0.41 ENST00000536441.1
sestrin 3
chr17_-_56405407 0.40 ENST00000343736.4
benzodiazepine receptor (peripheral) associated protein 1
chr22_+_29469012 0.39 ENST00000400335.4
ENST00000400338.2
kringle containing transmembrane protein 1
chr3_-_52001448 0.39 ENST00000461554.1
ENST00000395013.3
ENST00000428823.2
ENST00000483411.1
ENST00000461544.1
ENST00000355852.2
poly(rC) binding protein 4
chr19_+_41725140 0.38 ENST00000359092.3
AXL receptor tyrosine kinase
chr16_-_30134524 0.38 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
mitogen-activated protein kinase 3
chr2_-_128399706 0.38 ENST00000426981.1
LIM and senescent cell antigen-like domains 2
chr9_-_136004782 0.37 ENST00000393157.3
ral guanine nucleotide dissociation stimulator
chr16_+_31483451 0.37 ENST00000565360.1
ENST00000361773.3
transforming growth factor beta 1 induced transcript 1
chr22_+_29469100 0.36 ENST00000327813.5
ENST00000407188.1
kringle containing transmembrane protein 1
chr12_+_56546363 0.35 ENST00000551834.1
ENST00000552568.1
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr11_+_65343494 0.35 ENST00000309295.4
ENST00000533237.1
EH domain binding protein 1-like 1
chr5_-_59189545 0.34 ENST00000340635.6
phosphodiesterase 4D, cAMP-specific
chr16_+_31483374 0.34 ENST00000394863.3
transforming growth factor beta 1 induced transcript 1
chr11_-_1619524 0.34 ENST00000412090.1
keratin associated protein 5-2
chr10_+_111767720 0.33 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chrX_+_110339439 0.33 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_+_71276609 0.33 ENST00000398531.1
ENST00000376536.4
keratin associated protein 5-10
chr6_-_71012773 0.33 ENST00000370496.3
ENST00000357250.6
collagen, type IX, alpha 1
chr14_-_106518922 0.31 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr11_-_72852320 0.31 ENST00000422375.1
FCH and double SH3 domains 2
chr21_-_18985158 0.31 ENST00000339775.6
BTG family, member 3
chr17_+_48351785 0.31 ENST00000507382.1
transmembrane protein 92
chr16_-_3030283 0.30 ENST00000572619.1
ENST00000574415.1
ENST00000440027.2
ENST00000572059.1
protein kinase, membrane associated tyrosine/threonine 1
chr14_-_101351184 0.30 ENST00000534062.1
retrotransposon-like 1
chr16_-_56485257 0.29 ENST00000300291.5
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr11_-_71293921 0.29 ENST00000398530.1
keratin associated protein 5-11
chr2_-_74619152 0.29 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr11_-_61062762 0.28 ENST00000335613.5
von Willebrand factor C and EGF domains
chr22_-_30642782 0.28 ENST00000249075.3
leukemia inhibitory factor
chr9_-_135819987 0.28 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr4_-_47839966 0.28 ENST00000273857.4
ENST00000505909.1
ENST00000502252.1
corin, serine peptidase
chr15_-_43910438 0.27 ENST00000432436.1
stereocilin
chr17_-_3819751 0.27 ENST00000225538.3
purinergic receptor P2X, ligand-gated ion channel, 1
chr16_+_33006369 0.26 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr20_+_18269121 0.26 ENST00000377671.3
ENST00000360010.5
ENST00000396026.3
ENST00000402618.2
ENST00000401790.1
ENST00000434018.1
ENST00000538547.1
ENST00000535822.1
zinc finger protein 133
chr12_-_112819896 0.26 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr7_+_75024903 0.26 ENST00000323819.3
ENST00000430211.1
tripartite motif containing 73
chr14_+_45605157 0.25 ENST00000542564.2
Fanconi anemia, complementation group M
chr4_-_47840112 0.25 ENST00000504584.1
corin, serine peptidase
chr19_+_56116771 0.25 ENST00000568956.1
zinc finger protein 865
chr19_+_39904168 0.25 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_+_154193643 0.25 ENST00000456325.1
ubiquitin associated protein 2-like
chr16_-_29910853 0.23 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr7_+_72742178 0.23 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FK506 binding protein 6, 36kDa
chr14_-_51562037 0.23 ENST00000338969.5
tripartite motif containing 9
chr19_+_45973360 0.22 ENST00000589593.1
FBJ murine osteosarcoma viral oncogene homolog B
chr2_-_152955537 0.22 ENST00000201943.5
ENST00000539935.1
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_152955213 0.22 ENST00000427385.1
calcium channel, voltage-dependent, beta 4 subunit
chr20_+_37353084 0.22 ENST00000217420.1
solute carrier family 32 (GABA vesicular transporter), member 1
chr16_-_46723066 0.22 ENST00000299138.7
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr4_-_114682936 0.21 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
calcium/calmodulin-dependent protein kinase II delta
chr15_+_92397051 0.20 ENST00000424469.2
solute carrier organic anion transporter family, member 3A1
chr2_+_16080659 0.20 ENST00000281043.3
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr7_+_72742162 0.20 ENST00000431982.2
FK506 binding protein 6, 36kDa
chr1_+_62902308 0.20 ENST00000339950.4
ubiquitin specific peptidase 1
chr4_-_114682597 0.19 ENST00000394524.3
calcium/calmodulin-dependent protein kinase II delta
chr19_+_45973120 0.19 ENST00000592811.1
ENST00000586615.1
FBJ murine osteosarcoma viral oncogene homolog B
chr16_-_29910365 0.19 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
seizure related 6 homolog (mouse)-like 2
chr7_-_72439997 0.19 ENST00000285805.3
tripartite motif containing 74
chr6_-_97345689 0.18 ENST00000316149.7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chrX_+_48398053 0.18 ENST00000537536.1
ENST00000418627.1
TBC1 domain family, member 25
chr1_+_151138500 0.17 ENST00000368905.4
sodium channel modifier 1
chr11_-_72852958 0.17 ENST00000458644.2
FCH and double SH3 domains 2
chr13_+_53602894 0.16 ENST00000219022.2
olfactomedin 4
chr9_-_140115775 0.16 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr11_+_64053311 0.15 ENST00000540370.1
G protein-coupled receptor 137
chrX_-_71526999 0.15 ENST00000453707.2
ENST00000373619.3
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr14_+_45605127 0.15 ENST00000556036.1
ENST00000267430.5
Fanconi anemia, complementation group M
chr12_-_52715179 0.15 ENST00000293670.3
keratin 83
chr16_+_32063311 0.14 ENST00000426099.1
AC142381.1
chr16_+_56485402 0.14 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr11_-_73309112 0.14 ENST00000450446.2
family with sequence similarity 168, member A
chr17_+_48046671 0.14 ENST00000505318.2
distal-less homeobox 4
chr22_-_30661807 0.14 ENST00000403389.1
oncostatin M
chr11_-_124180733 0.14 ENST00000357821.2
olfactory receptor, family 8, subfamily D, member 1
chr19_-_56048456 0.14 ENST00000413299.1
SH3 domain binding kinase family, member 2
chr17_+_48046538 0.14 ENST00000240306.3
distal-less homeobox 4
chr10_+_24497704 0.13 ENST00000376456.4
ENST00000458595.1
KIAA1217
chr1_-_204654481 0.12 ENST00000367176.3
leucine rich repeat neuronal 2
chr20_-_18038521 0.12 ENST00000278780.6
ovo-like zinc finger 2
chr6_+_38690622 0.11 ENST00000327475.6
dynein, axonemal, heavy chain 8
chr17_-_3599327 0.11 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_+_20483037 0.11 ENST00000399044.1
CMT1A duplicated region transcript 15-like 2
chr5_-_137368726 0.11 ENST00000420893.2
ENST00000425075.2
family with sequence similarity 13, member B
chr6_-_31940065 0.11 ENST00000375349.3
ENST00000337523.5
decapping exoribonuclease
chr17_-_50237374 0.10 ENST00000442502.2
carbonic anhydrase X
chrX_-_16888276 0.09 ENST00000493145.1
retinoblastoma binding protein 7
chr6_-_150039170 0.09 ENST00000458696.2
ENST00000392273.3
large tumor suppressor kinase 1
chr3_+_124303539 0.08 ENST00000428018.2
kalirin, RhoGEF kinase
chr4_-_99850243 0.08 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr16_+_31128978 0.07 ENST00000448516.2
ENST00000219797.4
K(lysine) acetyltransferase 8
chr1_+_22962948 0.07 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr18_-_51750948 0.07 ENST00000583046.1
ENST00000398398.2
methyl-CpG binding domain protein 2
chr10_-_126849588 0.07 ENST00000411419.2
C-terminal binding protein 2
chr4_+_55095428 0.07 ENST00000508170.1
ENST00000512143.1
platelet-derived growth factor receptor, alpha polypeptide
chr5_-_137368708 0.07 ENST00000033079.3
family with sequence similarity 13, member B
chr16_+_46723552 0.06 ENST00000219097.2
ENST00000568364.2
origin recognition complex, subunit 6
chr12_+_107168342 0.06 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr9_-_95527079 0.06 ENST00000356884.6
ENST00000375512.3
bicaudal D homolog 2 (Drosophila)
chr15_+_74833518 0.06 ENST00000346246.5
AT rich interactive domain 3B (BRIGHT-like)
chr3_-_197024394 0.06 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
discs, large homolog 1 (Drosophila)
chr19_-_44258770 0.06 ENST00000601925.1
ENST00000602222.1
ENST00000599804.1
SMG9 nonsense mediated mRNA decay factor
chr20_+_62716348 0.05 ENST00000349451.3
opiate receptor-like 1
chr22_+_51112800 0.04 ENST00000414786.2
SH3 and multiple ankyrin repeat domains 3
chr6_+_43044003 0.04 ENST00000230419.4
ENST00000476760.1
ENST00000471863.1
ENST00000349241.2
ENST00000352931.2
ENST00000345201.2
protein tyrosine kinase 7
chr3_-_15374033 0.03 ENST00000253688.5
ENST00000383791.3
SH3-domain binding protein 5 (BTK-associated)
chr6_+_32812568 0.03 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr9_+_34652164 0.03 ENST00000441545.2
ENST00000553620.1
interleukin 11 receptor, alpha
chr16_-_18812746 0.03 ENST00000546206.2
ENST00000562819.1
ENST00000562234.2
ENST00000304414.7
ENST00000567078.2
ADP-ribosylation factor-like 6 interacting protein 1
Uncharacterized protein
chr19_+_45843994 0.03 ENST00000391946.2
kinesin light chain 3
chr19_-_44258733 0.03 ENST00000597586.1
ENST00000596714.1
SMG9 nonsense mediated mRNA decay factor
chr12_+_57522439 0.02 ENST00000338962.4
low density lipoprotein receptor-related protein 1
chr11_-_111170526 0.01 ENST00000355430.4
colorectal cancer associated 1
chr14_+_105047478 0.01 ENST00000410013.1
chromosome 14 open reading frame 180
chr1_+_151138526 0.00 ENST00000368902.1
sodium channel modifier 1
chr11_-_73309228 0.00 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of PLAG1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.3 1.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 0.7 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 0.7 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.7 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2 1.4 GO:0034436 glycoprotein transport(GO:0034436)
0.2 1.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.8 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 1.7 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 2.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 0.5 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 3.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 1.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.6 GO:0018277 protein deamination(GO:0018277)
0.1 0.7 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.4 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.5 GO:0036269 swimming behavior(GO:0036269)
0.1 0.7 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.4 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.2 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.9 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0051029 rRNA transport(GO:0051029)
0.1 0.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0002351 serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 1.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.8 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.7 GO:0006012 galactose metabolic process(GO:0006012)
0.0 1.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 1.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 1.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 1.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 1.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.0 GO:0097107 postsynaptic density assembly(GO:0097107)
0.0 1.0 GO:0042551 neuron maturation(GO:0042551)
0.0 0.4 GO:0051412 response to corticosterone(GO:0051412)
0.0 1.3 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 2.5 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.7 GO:0005869 dynactin complex(GO:0005869)
0.1 0.4 GO:1990425 ryanodine receptor complex(GO:1990425)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:1990812 growth cone filopodium(GO:1990812)
0.1 2.8 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 2.5 GO:0045095 keratin filament(GO:0045095)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426) kinocilium(GO:0060091)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.2 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 6.4 GO:0098793 presynapse(GO:0098793)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070538 oleic acid binding(GO:0070538)
0.4 1.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.4 1.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 1.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 3.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.4 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 2.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.0 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.7 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0048156 tau protein binding(GO:0048156)
0.0 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.2 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.2 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs