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Illumina Body Map 2, young vs old

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Results for POU4F1_POU4F3

Z-value: 0.19

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
POU4F1
ENSG00000152192.6 POU class 4 homeobox 1
POU4F3
ENSG00000091010.4 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F1hg19_v2_chr13_-_79177673_791777010.281.2e-01Click!
POU4F3hg19_v2_chr5_+_145718587_1457186070.105.8e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_38821373 3.92 ENST00000394052.3
KRT222
keratin 222
chr1_+_50574585 3.79 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr4_+_74269956 3.68 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr18_-_31803435 3.24 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4
nucleolar protein 4
chr4_-_72649763 3.08 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr2_-_88285309 3.07 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr12_+_41221794 3.02 ENST00000547849.1
CNTN1
contactin 1
chr12_+_51985001 2.94 ENST00000354534.6
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr3_+_68055366 2.78 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr22_+_30476163 2.63 ENST00000336726.6
HORMAD2
HORMA domain containing 2
chr14_-_65409438 2.58 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_-_136847099 2.53 ENST00000438100.2
MAP7
microtubule-associated protein 7
chr12_+_51984657 2.47 ENST00000550891.1
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_138724677 2.43 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chrX_-_138724994 2.37 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr9_+_34458771 2.28 ENST00000437363.1
ENST00000242317.4
DNAI1
dynein, axonemal, intermediate chain 1
chr3_+_35722487 2.26 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_136847610 2.26 ENST00000454590.1
ENST00000432797.2
MAP7
microtubule-associated protein 7
chr19_+_17865011 2.23 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1
FCH domain only 1
chr3_-_52860850 2.22 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr12_+_79357815 2.12 ENST00000547046.1
SYT1
synaptotagmin I
chr2_+_87135076 2.08 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr14_-_65409502 1.89 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr9_+_34458851 1.86 ENST00000545019.1
DNAI1
dynein, axonemal, intermediate chain 1
chr3_+_35722844 1.84 ENST00000436702.1
ENST00000438071.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_35722424 1.83 ENST00000396481.2
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chrX_-_106146547 1.79 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr18_-_31803169 1.78 ENST00000590712.1
NOL4
nucleolar protein 4
chr18_+_76740189 1.78 ENST00000537592.2
ENST00000575389.2
SALL3
spalt-like transcription factor 3
chr22_+_30477000 1.75 ENST00000403975.1
HORMAD2
HORMA domain containing 2
chr12_+_41221975 1.75 ENST00000552913.1
CNTN1
contactin 1
chr3_+_46742823 1.71 ENST00000326431.3
TMIE
transmembrane inner ear
chr19_-_36304201 1.71 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr1_+_63063152 1.70 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr2_+_185463093 1.61 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr16_-_51185172 1.55 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr11_-_35441524 1.55 ENST00000395750.1
ENST00000449068.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_-_51185149 1.51 ENST00000566102.1
ENST00000541611.1
SALL1
spalt-like transcription factor 1
chr11_-_35441597 1.50 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_+_49740700 1.49 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr14_-_101036119 1.47 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr5_+_139739772 1.47 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr3_-_194072019 1.41 ENST00000429275.1
ENST00000323830.3
CPN2
carboxypeptidase N, polypeptide 2
chr17_-_50236039 1.34 ENST00000451037.2
CA10
carbonic anhydrase X
chr17_+_18012020 1.32 ENST00000205890.5
MYO15A
myosin XVA
chr16_+_24621546 1.31 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr21_-_37914898 1.27 ENST00000399136.1
CLDN14
claudin 14
chr2_-_209054709 1.26 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80
chromosome 2 open reading frame 80
chr10_-_128359008 1.25 ENST00000488181.1
C10orf90
chromosome 10 open reading frame 90
chr12_-_9885888 1.24 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr19_+_19639704 1.21 ENST00000514277.4
YJEFN3
YjeF N-terminal domain containing 3
chr19_+_19639670 1.21 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr11_-_7698453 1.16 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr17_-_10741762 1.16 ENST00000580256.2
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr2_+_182850551 1.14 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_179318295 1.11 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr19_-_13734804 1.11 ENST00000574974.1
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr15_+_58724184 1.09 ENST00000433326.2
LIPC
lipase, hepatic
chr4_-_21546272 1.07 ENST00000509207.1
KCNIP4
Kv channel interacting protein 4
chr9_-_123812542 1.07 ENST00000223642.1
C5
complement component 5
chr1_+_149239529 1.07 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr1_+_101003687 1.04 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr1_-_108231101 1.04 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr1_+_160336851 1.04 ENST00000302101.5
NHLH1
nescient helix loop helix 1
chr9_-_74675521 1.00 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr4_+_159236462 0.99 ENST00000460056.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr2_-_183387283 0.97 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr12_+_100750846 0.95 ENST00000323346.5
SLC17A8
solute carrier family 17 (vesicular glutamate transporter), member 8
chr10_-_128359074 0.95 ENST00000544758.1
C10orf90
chromosome 10 open reading frame 90
chr5_-_13944652 0.93 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr11_+_58706944 0.90 ENST00000532726.1
GLYATL1
glycine-N-acyltransferase-like 1
chrX_-_142605301 0.90 ENST00000370503.2
SPANXN3
SPANX family, member N3
chr15_+_76352178 0.89 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr22_-_30970560 0.88 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr8_-_110986918 0.88 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr11_-_83393429 0.88 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr2_+_179317994 0.87 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr6_-_10115007 0.87 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr11_+_98891797 0.87 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5
contactin 5
chr17_-_72855989 0.84 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr20_+_30555805 0.82 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr17_-_56492989 0.80 ENST00000583753.1
RNF43
ring finger protein 43
chr5_-_135290705 0.79 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr19_-_51141196 0.78 ENST00000338916.4
SYT3
synaptotagmin III
chr1_-_197036364 0.78 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr11_-_83393457 0.77 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chrX_-_72097698 0.77 ENST00000373530.1
DMRTC1
DMRT-like family C1
chr2_-_183387430 0.77 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr1_+_47603109 0.77 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chr3_-_185826855 0.75 ENST00000306376.5
ETV5
ets variant 5
chrX_+_72062802 0.74 ENST00000373533.1
DMRTC1B
DMRT-like family C1B
chr10_-_128210005 0.74 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
C10orf90
chromosome 10 open reading frame 90
chr2_+_133174147 0.74 ENST00000329321.3
GPR39
G protein-coupled receptor 39
chrX_+_72062617 0.74 ENST00000440247.1
DMRTC1B
DMRT-like family C1B
chr5_-_11589131 0.72 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr7_-_107880508 0.72 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr18_-_70305745 0.72 ENST00000581073.1
CBLN2
cerebellin 2 precursor
chr11_-_83393303 0.70 ENST00000398304.1
ENST00000420775.2
DLG2
discs, large homolog 2 (Drosophila)
chr17_+_28268623 0.69 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr18_+_47088401 0.69 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr2_-_183387064 0.67 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_-_100026280 0.67 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr19_+_54466179 0.65 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr11_-_26593649 0.65 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_-_11588907 0.63 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr12_-_120241187 0.63 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr18_-_24443151 0.62 ENST00000440832.3
AQP4
aquaporin 4
chr1_-_248845629 0.60 ENST00000342623.3
OR14I1
olfactory receptor, family 14, subfamily I, member 1
chr22_-_38506619 0.60 ENST00000332536.5
ENST00000381669.3
BAIAP2L2
BAI1-associated protein 2-like 2
chr2_+_87144738 0.60 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr12_+_81664424 0.59 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3
RP11-121G22.3
chr4_-_69817481 0.59 ENST00000251566.4
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_-_39402798 0.58 ENST00000571838.1
CTC-360G5.1
coiled-coil glutamate-rich protein 2
chr9_-_16253112 0.58 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr2_+_197577841 0.56 ENST00000409270.1
CCDC150
coiled-coil domain containing 150
chr11_-_88799113 0.55 ENST00000393294.3
GRM5
glutamate receptor, metabotropic 5
chr7_+_99195677 0.55 ENST00000431679.1
GS1-259H13.2
GS1-259H13.2
chr22_-_30970498 0.53 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr7_-_15014398 0.50 ENST00000437998.1
DGKB
diacylglycerol kinase, beta 90kDa
chr6_-_127840021 0.50 ENST00000465909.2
SOGA3
SOGA family member 3
chr6_-_76782371 0.50 ENST00000369950.3
ENST00000369963.3
IMPG1
interphotoreceptor matrix proteoglycan 1
chr11_-_69587718 0.49 ENST00000602104.1
AP001888.1
Uncharacterized protein
chr19_-_55677920 0.47 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr19_+_56368803 0.45 ENST00000587891.1
NLRP4
NLR family, pyrin domain containing 4
chr9_+_35673853 0.45 ENST00000378357.4
CA9
carbonic anhydrase IX
chr3_-_33686925 0.44 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr6_-_26108355 0.44 ENST00000338379.4
HIST1H1T
histone cluster 1, H1t
chr12_+_110011571 0.43 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr14_+_101297740 0.41 ENST00000555928.1
MEG3
maternally expressed 3 (non-protein coding)
chr3_-_74570291 0.41 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr1_-_222014008 0.41 ENST00000431729.1
RP11-191N8.2
RP11-191N8.2
chr2_+_182850743 0.41 ENST00000409702.1
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr5_-_135290651 0.40 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr13_-_20110902 0.38 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr4_-_103998439 0.38 ENST00000503230.1
ENST00000503818.1
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr2_+_65663812 0.38 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr17_+_37783197 0.38 ENST00000582680.1
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_35013217 0.38 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr10_+_90346519 0.38 ENST00000371939.3
LIPJ
lipase, family member J
chr11_+_86085778 0.37 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81
coiled-coil domain containing 81
chr2_+_191221240 0.37 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr13_-_70682590 0.37 ENST00000377844.4
KLHL1
kelch-like family member 1
chr22_+_17956618 0.36 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr1_-_47017199 0.36 ENST00000481882.2
KNCN
kinocilin
chr6_-_127840336 0.36 ENST00000525778.1
SOGA3
SOGA family member 3
chr22_+_43011247 0.35 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr9_-_21166659 0.34 ENST00000380225.1
IFNA21
interferon, alpha 21
chr2_-_26781521 0.34 ENST00000403946.3
ENST00000272371.2
OTOF
otoferlin
chr11_+_22696314 0.34 ENST00000532398.1
ENST00000433790.1
GAS2
growth arrest-specific 2
chr3_-_33686743 0.34 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr1_-_154580616 0.34 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr10_-_128975273 0.34 ENST00000424811.2
FAM196A
family with sequence similarity 196, member A
chr17_+_37782955 0.34 ENST00000580825.1
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr17_+_37783453 0.33 ENST00000579000.1
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr20_-_29978383 0.33 ENST00000339144.3
ENST00000376321.3
DEFB119
defensin, beta 119
chr22_-_39268308 0.33 ENST00000407418.3
CBX6
chromobox homolog 6
chr1_+_161691353 0.32 ENST00000367948.2
FCRLB
Fc receptor-like B
chr4_+_68424434 0.32 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr14_+_22580233 0.31 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr2_+_47454054 0.31 ENST00000426892.1
AC106869.2
AC106869.2
chr17_-_37123646 0.30 ENST00000378079.2
FBXO47
F-box protein 47
chr10_+_104614008 0.30 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chr6_+_126102292 0.30 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr12_-_23737534 0.30 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr11_-_26593677 0.30 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr4_+_146601356 0.29 ENST00000438731.1
ENST00000511965.1
C4orf51
chromosome 4 open reading frame 51
chr9_-_107361788 0.29 ENST00000374779.2
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr17_+_37783170 0.29 ENST00000254079.4
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_40973618 0.28 ENST00000420187.1
AC007317.1
AC007317.1
chr4_-_122085469 0.27 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr4_-_16085314 0.27 ENST00000510224.1
PROM1
prominin 1
chr3_-_167371704 0.27 ENST00000488012.1
WDR49
WD repeat domain 49
chr12_+_130554803 0.27 ENST00000535487.1
RP11-474D1.2
RP11-474D1.2
chr3_-_167371740 0.26 ENST00000466760.1
ENST00000479765.1
WDR49
WD repeat domain 49
chr10_-_112678904 0.26 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr14_+_22978168 0.26 ENST00000390505.1
TRAJ32
T cell receptor alpha joining 32
chr16_-_67217844 0.26 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr1_-_95538492 0.26 ENST00000370205.5
ALG14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr11_-_111649074 0.26 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr19_-_23941639 0.25 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr10_+_135207598 0.25 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr2_-_183106641 0.24 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr6_-_2634820 0.24 ENST00000296847.3
C6orf195
chromosome 6 open reading frame 195
chr4_-_16085340 0.24 ENST00000508167.1
PROM1
prominin 1
chr19_-_46580352 0.24 ENST00000601672.1
IGFL4
IGF-like family member 4
chr16_-_52061283 0.24 ENST00000566314.1
C16orf97
chromosome 16 open reading frame 97
chr3_-_185826718 0.23 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr10_-_112678692 0.23 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr5_-_39270725 0.23 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr9_-_4666421 0.23 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr13_+_113698946 0.23 ENST00000397021.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr10_+_135207623 0.23 ENST00000317502.6
ENST00000432508.3
MTG1
mitochondrial ribosome-associated GTPase 1
chr2_+_169757750 0.23 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr9_-_4666337 0.22 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr20_+_57875758 0.22 ENST00000395654.3
EDN3
endothelin 3
chr10_+_104613980 0.21 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr13_+_46039037 0.21 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr19_-_55677999 0.21 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
DNAAF3
dynein, axonemal, assembly factor 3
chr6_-_52859046 0.20 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr6_-_161695074 0.20 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 3.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 4.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.4 2.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 1.8 GO:0001757 somite specification(GO:0001757)
0.3 0.8 GO:0033058 directional locomotion(GO:0033058)
0.3 3.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.0 GO:0061743 motor learning(GO:0061743)
0.2 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 5.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 1.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 5.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.8 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 1.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 3.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 5.6 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 3.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.1 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.9 GO:0046710 GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120)
0.0 4.8 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 5.1 GO:0021549 cerebellum development(GO:0021549)
0.0 0.2 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 5.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 3.9 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 5.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.2 GO:0042330 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 3.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0050777 negative regulation of immune response(GO:0050777)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.3 GO:0007420 brain development(GO:0007420)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 GO:0036157 outer dynein arm(GO:0036157)
0.3 1.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 2.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 5.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.1 GO:0010369 chromocenter(GO:0010369)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 6.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 4.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 9.2 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.8 2.4 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.4 1.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 2.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 3.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.2 0.9 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.2 2.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 5.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 4.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 1.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 3.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.8 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.0 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 2.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 5.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 4.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 4.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 5.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 4.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling