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Illumina Body Map 2, young vs old

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Results for POU4F2

Z-value: 0.52

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Transcription factors associated with POU4F2

Gene Symbol Gene ID Gene Info
POU4F2
ENSG00000151615.3 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F2hg19_v2_chr4_+_147560042_1475600460.029.1e-01Click!

Activity profile of POU4F2 motif

Sorted Z-values of POU4F2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_78432907 2.78 ENST00000286758.4
CXCL13
chemokine (C-X-C motif) ligand 13
chr10_-_73848531 2.75 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_73848086 2.51 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_+_22356029 2.22 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr3_+_108541545 1.81 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr7_-_81399355 1.81 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399329 1.74 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399438 1.73 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr9_+_125132803 1.71 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_198607801 1.69 ENST00000367379.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr14_+_22891362 1.68 ENST00000390469.2
TRDV2
T cell receptor delta variable 2
chr3_+_108541608 1.68 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr7_-_81399411 1.67 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_22564294 1.66 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr9_+_125133315 1.60 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_50574585 1.56 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr1_+_198608146 1.52 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_+_169013666 1.50 ENST00000359299.3
ANXA10
annexin A10
chr11_+_118175132 1.43 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr1_+_198608292 1.37 ENST00000418674.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_-_158300556 1.36 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr12_+_93130311 1.35 ENST00000344636.3
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr14_+_97925151 1.24 ENST00000554862.1
ENST00000554260.1
ENST00000499910.2
CTD-2506J14.1
CTD-2506J14.1
chr1_-_47655686 1.21 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr17_-_64225508 1.13 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_70780572 1.10 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr9_+_125133467 1.07 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr4_+_159442878 1.03 ENST00000307765.5
ENST00000423548.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr3_+_121774202 0.99 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr16_-_4852915 0.96 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr7_-_81399287 0.95 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr14_+_22987424 0.95 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr20_-_7238861 0.92 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr4_+_159443024 0.92 ENST00000448688.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr17_-_79623597 0.90 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr4_-_36245561 0.90 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_-_89746173 0.84 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr3_+_115342349 0.82 ENST00000393780.3
GAP43
growth associated protein 43
chr4_+_159443090 0.81 ENST00000343542.5
ENST00000470033.1
RXFP1
relaxin/insulin-like family peptide receptor 1
chr19_-_10446449 0.80 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr8_+_50824233 0.77 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr6_-_25874440 0.75 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr6_-_109776901 0.74 ENST00000431946.1
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr14_+_42077552 0.71 ENST00000554120.1
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr11_-_795170 0.70 ENST00000481290.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr4_-_176733377 0.69 ENST00000505375.1
GPM6A
glycoprotein M6A
chr17_+_73539339 0.69 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr12_-_89746264 0.67 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr6_-_109777128 0.67 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr17_-_9929581 0.66 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr6_-_111136513 0.66 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr8_-_18541603 0.65 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_204183071 0.65 ENST00000308302.3
GOLT1A
golgi transport 1A
chr11_+_73498898 0.64 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48
mitochondrial ribosomal protein L48
chr6_+_12717892 0.62 ENST00000379350.1
PHACTR1
phosphatase and actin regulator 1
chr13_+_46039037 0.56 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr2_+_44502630 0.56 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr17_-_7832753 0.54 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr15_-_74421477 0.52 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr4_-_123542224 0.51 ENST00000264497.3
IL21
interleukin 21
chr2_+_21444025 0.51 ENST00000435237.1
ENST00000457901.1
AC067959.1
AC067959.1
chr10_+_18549645 0.47 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr20_-_21086975 0.46 ENST00000420705.1
ENST00000593272.1
LINC00237
long intergenic non-protein coding RNA 237
chr11_-_795286 0.45 ENST00000533385.1
ENST00000527723.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_190446759 0.45 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr19_-_36304201 0.44 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr1_+_40506392 0.43 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr1_-_44482979 0.43 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_-_7698599 0.43 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr8_-_49833978 0.43 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr2_+_191792376 0.42 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr3_+_63428752 0.42 ENST00000295894.5
SYNPR
synaptoporin
chr2_+_17997763 0.40 ENST00000281047.3
MSGN1
mesogenin 1
chr2_+_44502597 0.40 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr17_+_61151306 0.40 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr2_+_54951679 0.39 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr12_+_79371565 0.39 ENST00000551304.1
SYT1
synaptotagmin I
chr1_+_66820058 0.39 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chrX_-_133931164 0.38 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr20_+_11008408 0.36 ENST00000378252.1
C20orf187
chromosome 20 open reading frame 187
chr6_+_10521574 0.36 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr4_+_104346194 0.35 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr16_+_28505955 0.35 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr6_+_130339710 0.35 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr14_+_38033252 0.33 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr20_+_5987890 0.31 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr2_+_35056422 0.29 ENST00000592523.1
ENST00000588944.1
ENST00000585391.1
ENST00000591221.1
ENST00000586769.1
ENST00000588650.1
AC012593.1
AC012593.1
chr6_-_111136299 0.28 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr1_+_40506255 0.27 ENST00000421589.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr17_-_38956205 0.27 ENST00000306658.7
KRT28
keratin 28
chr6_-_89927151 0.26 ENST00000454853.2
GABRR1
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr4_+_147145709 0.25 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr15_-_37393406 0.25 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr5_+_55354822 0.24 ENST00000511861.1
CTD-2227I18.1
CTD-2227I18.1
chr7_+_142919130 0.24 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr12_-_52779433 0.23 ENST00000257951.3
KRT84
keratin 84
chr5_-_134914673 0.23 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr15_-_98417780 0.22 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr9_-_5830768 0.22 ENST00000381506.3
ERMP1
endoplasmic reticulum metallopeptidase 1
chr1_-_182641367 0.21 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr11_-_107729887 0.21 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr8_-_49834299 0.21 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr19_-_7697857 0.21 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr4_-_169401628 0.20 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr9_-_79520989 0.18 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2
prune homolog 2 (Drosophila)
chr12_-_30887948 0.17 ENST00000433722.2
CAPRIN2
caprin family member 2
chrX_+_139791917 0.15 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_+_56510368 0.15 ENST00000546591.1
ENST00000501597.3
RPL41
ribosomal protein L41
chr1_-_193028621 0.14 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr4_-_10686373 0.14 ENST00000442825.2
CLNK
cytokine-dependent hematopoietic cell linker
chr6_-_74231444 0.14 ENST00000331523.2
ENST00000356303.2
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr10_+_95372289 0.13 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr11_+_31531291 0.13 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr13_-_74993252 0.12 ENST00000325811.1
AL355390.1
Uncharacterized protein
chr1_-_182640988 0.11 ENST00000367556.1
RGS8
regulator of G-protein signaling 8
chrX_-_18690210 0.11 ENST00000379984.3
RS1
retinoschisin 1
chr7_-_142919360 0.09 ENST00000595842.1
AC073342.1
HCG2002387; Uncharacterized protein
chr1_-_193028632 0.09 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chrX_+_3189861 0.09 ENST00000457435.1
ENST00000420429.2
CXorf28
chromosome X open reading frame 28
chr5_-_140998616 0.09 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chrX_+_133930798 0.08 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr11_-_125550726 0.08 ENST00000315608.3
ENST00000530048.1
ACRV1
acrosomal vesicle protein 1
chr1_-_182641037 0.08 ENST00000483095.2
RGS8
regulator of G-protein signaling 8
chr11_-_31531121 0.08 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_-_107729504 0.07 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr10_+_99205894 0.07 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chrX_+_68835911 0.06 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr4_+_169418195 0.05 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr1_+_229440129 0.04 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr16_-_20416053 0.04 ENST00000302451.4
PDILT
protein disulfide isomerase-like, testis expressed
chr5_-_87516448 0.04 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr9_+_77230499 0.03 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr6_-_138820624 0.03 ENST00000343505.5
NHSL1
NHS-like 1
chr16_+_89228757 0.02 ENST00000565008.1
LINC00304
long intergenic non-protein coding RNA 304
chr6_-_111804905 0.02 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_+_193028552 0.02 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr18_-_71959159 0.01 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr15_+_45544426 0.01 ENST00000347644.3
ENST00000560438.1
SLC28A2
solute carrier family 28 (concentrative nucleoside transporter), member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.7 2.8 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.6 7.9 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 3.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.4 GO:0019417 sulfur oxidation(GO:0019417)
0.3 1.0 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 1.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 5.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 4.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.0 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.5 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 1.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.9 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 2.5 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 6.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 4.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 5.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.7 2.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 5.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 7.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 3.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 4.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 1.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 1.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 1.4 GO:0071949 FAD binding(GO:0071949)
0.0 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 7.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 6.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 4.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters