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Illumina Body Map 2, young vs old

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Results for PPARG

Z-value: 0.02

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Transcription factors associated with PPARG

Gene Symbol Gene ID Gene Info
PPARG
ENSG00000132170.15 peroxisome proliferator activated receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PPARGhg19_v2_chr3_+_12329397_123294330.281.3e-01Click!

Activity profile of PPARG motif

Sorted Z-values of PPARG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_49864746 10.32 ENST00000598810.1
TEAD2
TEA domain family member 2
chr22_+_23029188 5.58 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_23229960 5.41 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr14_-_106330458 5.20 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr22_+_22676808 4.37 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr2_-_89513402 4.32 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr8_+_11351494 4.24 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr8_+_11351876 4.04 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr14_-_106453155 4.03 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr14_-_106642049 3.92 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr22_+_23264766 3.91 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr10_-_72362515 3.89 ENST00000373209.2
ENST00000441259.1
PRF1
perforin 1 (pore forming protein)
chr14_-_106330824 3.84 ENST00000463911.1
IGHJ3
immunoglobulin heavy joining 3
chr19_+_544034 3.78 ENST00000592501.1
ENST00000264553.3
GZMM
granzyme M (lymphocyte met-ase 1)
chr19_-_10445399 3.32 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr7_+_80253387 3.30 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr22_+_22681656 3.18 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr11_+_14665373 3.09 ENST00000455098.2
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr14_-_106471723 3.04 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr2_-_219031709 3.02 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1
chr2_+_112895939 2.99 ENST00000331203.2
ENST00000409903.1
ENST00000409667.3
ENST00000409450.3
FBLN7
fibulin 7
chr14_-_106866934 2.96 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr19_+_50016411 2.95 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr12_-_53601000 2.81 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr19_+_18283959 2.73 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr9_-_130524695 2.73 ENST00000440630.1
ENST00000429553.1
SH2D3C
SH2 domain containing 3C
chr1_+_2487078 2.71 ENST00000426449.1
ENST00000434817.1
ENST00000435221.2
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr1_-_154941350 2.62 ENST00000444179.1
ENST00000414115.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr14_+_105046021 2.59 ENST00000557649.1
C14orf180
chromosome 14 open reading frame 180
chr9_-_117150243 2.58 ENST00000374088.3
AKNA
AT-hook transcription factor
chr1_-_183538319 2.54 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr17_-_18945798 2.47 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr20_+_43803517 2.45 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr22_+_23089870 2.43 ENST00000390311.2
IGLV3-16
immunoglobulin lambda variable 3-16
chr1_+_2487402 2.38 ENST00000451778.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr12_+_57849048 2.34 ENST00000266646.2
INHBE
inhibin, beta E
chr14_+_22748980 2.26 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr19_+_50016610 2.22 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_29817399 2.20 ENST00000545521.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_-_33447584 2.20 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr2_+_85922491 2.19 ENST00000526018.1
GNLY
granulysin
chr14_+_105046094 2.18 ENST00000331952.2
C14orf180
chromosome 14 open reading frame 180
chr7_-_150498426 2.17 ENST00000447204.2
TMEM176B
transmembrane protein 176B
chr22_+_23241661 2.15 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr7_+_150498610 2.15 ENST00000461345.1
TMEM176A
transmembrane protein 176A
chr9_-_139927462 2.15 ENST00000314412.6
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chrX_+_135252050 2.12 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr8_-_27850180 2.12 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
SCARA5
scavenger receptor class A, member 5 (putative)
chr17_+_42427826 2.12 ENST00000586443.1
GRN
granulin
chr14_+_105953246 2.11 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr1_+_207070775 2.10 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24
interleukin 24
chr4_-_25865159 2.07 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_+_14665263 2.05 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr14_+_105953204 2.00 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_+_21152259 2.00 ENST00000555835.1
ENST00000336811.6
RNASE4
ANG
ribonuclease, RNase A family, 4
angiogenin, ribonuclease, RNase A family, 5
chr14_+_22670455 1.98 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr8_-_27850141 1.97 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr11_-_5255861 1.96 ENST00000380299.3
HBD
hemoglobin, delta
chr11_+_75479763 1.96 ENST00000228027.7
DGAT2
diacylglycerol O-acyltransferase 2
chr17_+_45286706 1.95 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr19_+_49661037 1.95 ENST00000427978.2
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr20_+_31870927 1.95 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr8_-_25902876 1.93 ENST00000520164.1
EBF2
early B-cell factor 2
chr19_-_54784353 1.93 ENST00000391746.1
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr14_-_106331652 1.89 ENST00000390565.1
IGHJ1
immunoglobulin heavy joining 1
chr9_-_117150303 1.89 ENST00000312033.3
AKNA
AT-hook transcription factor
chr19_+_850985 1.88 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr7_+_150498783 1.87 ENST00000475536.1
ENST00000468689.1
TMEM176A
transmembrane protein 176A
chr1_+_200011711 1.84 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_-_7297519 1.84 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr7_-_75443118 1.83 ENST00000222902.2
CCL24
chemokine (C-C motif) ligand 24
chr19_+_42388437 1.81 ENST00000378152.4
ENST00000337665.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr5_-_180076613 1.80 ENST00000261937.6
ENST00000393347.3
FLT4
fms-related tyrosine kinase 4
chr12_-_96390108 1.78 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr9_+_95709733 1.76 ENST00000375482.3
FGD3
FYVE, RhoGEF and PH domain containing 3
chr6_-_112575838 1.74 ENST00000455073.1
LAMA4
laminin, alpha 4
chr1_+_10057274 1.74 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr22_-_24096630 1.73 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr17_-_7297833 1.71 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr19_+_51645556 1.71 ENST00000601682.1
ENST00000317643.6
ENST00000305628.7
ENST00000600577.1
SIGLEC7
sialic acid binding Ig-like lectin 7
chr2_-_87018784 1.70 ENST00000283635.3
ENST00000538832.1
CD8A
CD8a molecule
chr5_-_176936844 1.69 ENST00000510380.1
ENST00000510898.1
ENST00000357198.4
DOK3
docking protein 3
chr5_-_176936817 1.66 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr19_-_55836697 1.66 ENST00000438693.1
ENST00000591570.1
TMEM150B
transmembrane protein 150B
chr19_-_54746600 1.65 ENST00000245621.5
ENST00000270464.5
ENST00000419410.2
ENST00000391735.3
ENST00000396365.2
ENST00000440558.2
ENST00000407860.2
LILRA6
LILRB3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr11_-_5255696 1.65 ENST00000292901.3
ENST00000417377.1
HBD
hemoglobin, delta
chr7_+_75932863 1.61 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr19_+_49661079 1.61 ENST00000355712.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr5_-_180076580 1.60 ENST00000502649.1
FLT4
fms-related tyrosine kinase 4
chr10_+_114135952 1.59 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_-_180242576 1.59 ENST00000514438.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr14_+_23341513 1.59 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr10_-_129924468 1.57 ENST00000368653.3
MKI67
marker of proliferation Ki-67
chr12_+_6494285 1.56 ENST00000541102.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr17_-_34207295 1.55 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr4_+_15704573 1.55 ENST00000265016.4
BST1
bone marrow stromal cell antigen 1
chr21_-_43771226 1.51 ENST00000291526.4
TFF2
trefoil factor 2
chr4_+_15704679 1.51 ENST00000382346.3
BST1
bone marrow stromal cell antigen 1
chr1_+_12185949 1.50 ENST00000413146.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr5_-_180242534 1.48 ENST00000333055.3
ENST00000513431.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr7_-_100425112 1.47 ENST00000358173.3
EPHB4
EPH receptor B4
chr11_+_46740730 1.46 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2
coagulation factor II (thrombin)
chr22_+_37309662 1.45 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr3_+_148415571 1.45 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr17_+_61571746 1.44 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr6_-_52441713 1.44 ENST00000182527.3
TRAM2
translocation associated membrane protein 2
chr11_+_308143 1.44 ENST00000399817.4
IFITM2
interferon induced transmembrane protein 2
chr3_-_133748758 1.44 ENST00000493729.1
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr19_+_49660997 1.43 ENST00000598691.1
ENST00000252826.5
TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr20_+_48884002 1.42 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr12_-_96390063 1.42 ENST00000541929.1
HAL
histidine ammonia-lyase
chr19_-_13213954 1.42 ENST00000590974.1
LYL1
lymphoblastic leukemia derived sequence 1
chr11_+_75526212 1.41 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr1_+_158815588 1.41 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr19_-_55836669 1.38 ENST00000326652.4
TMEM150B
transmembrane protein 150B
chr8_-_82024290 1.38 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr11_+_67171548 1.37 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr11_+_67171358 1.36 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr5_-_150460539 1.36 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr6_-_112575758 1.35 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr10_+_102758105 1.34 ENST00000429732.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr2_-_32490801 1.34 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr3_+_52811596 1.34 ENST00000542827.1
ENST00000273283.2
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr11_+_67171391 1.34 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr5_+_149865377 1.33 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr7_-_38370536 1.33 ENST00000390343.2
TRGV8
T cell receptor gamma variable 8
chr2_+_201994208 1.32 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_+_142000747 1.32 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr5_-_176937351 1.31 ENST00000377112.4
ENST00000501403.2
ENST00000312943.6
DOK3
docking protein 3
chr2_+_201994042 1.30 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_-_62097927 1.30 ENST00000578313.1
ENST00000584084.1
ENST00000579788.1
ENST00000579687.1
ENST00000578379.1
ENST00000578892.1
ENST00000412356.1
ENST00000418105.1
ICAM2
intercellular adhesion molecule 2
chr19_-_1592828 1.28 ENST00000592012.1
MBD3
methyl-CpG binding domain protein 3
chr20_+_814349 1.28 ENST00000381941.3
FAM110A
family with sequence similarity 110, member A
chr2_+_28853443 1.24 ENST00000436775.1
PLB1
phospholipase B1
chr19_-_48894762 1.24 ENST00000600980.1
ENST00000330720.2
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr14_-_106066376 1.23 ENST00000412518.1
ENST00000428654.1
ENST00000427543.1
ENST00000420153.1
ENST00000577108.1
ENST00000576077.1
AL928742.12
IGHE
AL928742.12
immunoglobulin heavy constant epsilon
chr14_-_107283278 1.22 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr1_+_203274639 1.22 ENST00000290551.4
BTG2
BTG family, member 2
chr2_-_32490859 1.21 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr22_-_36784035 1.20 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr19_+_1407517 1.20 ENST00000336761.6
ENST00000233078.4
DAZAP1
DAZ associated protein 1
chr15_-_60690163 1.20 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr6_-_112575912 1.19 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr3_-_133748913 1.18 ENST00000310926.4
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr14_+_22409308 1.17 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr19_-_36399149 1.17 ENST00000585901.2
ENST00000544690.2
ENST00000424586.3
ENST00000262629.4
ENST00000589517.1
TYROBP
TYRO protein tyrosine kinase binding protein
chr12_+_66582919 1.17 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr4_-_682769 1.16 ENST00000507165.1
MFSD7
major facilitator superfamily domain containing 7
chr16_-_28518153 1.16 ENST00000356897.1
IL27
interleukin 27
chr11_+_76494253 1.14 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr5_+_32710736 1.14 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_+_1942580 1.14 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr22_+_24823517 1.13 ENST00000496258.1
ENST00000337539.7
ADORA2A
adenosine A2a receptor
chr11_-_59951430 1.13 ENST00000533409.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr12_+_109569155 1.12 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr20_+_816695 1.12 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr6_-_112575687 1.11 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr6_+_31465849 1.11 ENST00000399150.3
MICB
MHC class I polypeptide-related sequence B
chr19_+_45349630 1.11 ENST00000252483.5
PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_207925391 1.11 ENST00000358170.2
ENST00000354848.1
ENST00000322918.5
ENST00000367042.1
ENST00000367041.1
ENST00000357714.1
ENST00000322875.4
ENST00000367047.1
ENST00000441839.2
ENST00000361067.1
ENST00000360212.2
ENST00000480003.1
CD46
CD46 molecule, complement regulatory protein
chr8_-_9009079 1.11 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr15_+_41056218 1.10 ENST00000260447.4
GCHFR
GTP cyclohydrolase I feedback regulator
chr11_+_844406 1.09 ENST00000397404.1
TSPAN4
tetraspanin 4
chr5_+_176731572 1.08 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr12_-_125348329 1.08 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1
scavenger receptor class B, member 1
chr19_-_44031341 1.07 ENST00000600651.1
ETHE1
ethylmalonic encephalopathy 1
chr8_-_11725549 1.07 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB
cathepsin B
chr11_-_60720002 1.07 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr22_+_50312274 1.06 ENST00000404488.3
CRELD2
cysteine-rich with EGF-like domains 2
chr19_-_13213662 1.06 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr20_+_37434329 1.04 ENST00000299824.1
ENST00000373331.2
PPP1R16B
protein phosphatase 1, regulatory subunit 16B
chr16_+_55522536 1.04 ENST00000570283.1
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chrX_+_9433289 1.03 ENST00000422314.1
TBL1X
transducin (beta)-like 1X-linked
chrX_-_48325857 1.03 ENST00000376875.1
SLC38A5
solute carrier family 38, member 5
chrX_-_48326683 1.02 ENST00000440085.1
SLC38A5
solute carrier family 38, member 5
chr5_+_38445641 1.00 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr6_+_31465892 0.98 ENST00000252229.6
ENST00000427115.1
MICB
MHC class I polypeptide-related sequence B
chr9_-_136242956 0.98 ENST00000371989.3
ENST00000485435.2
SURF4
surfeit 4
chr2_+_219247021 0.98 ENST00000539932.1
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr11_-_82612549 0.97 ENST00000528082.1
ENST00000533126.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr6_-_24911195 0.96 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr12_-_39299406 0.96 ENST00000331366.5
CPNE8
copine VIII
chr19_+_56154913 0.95 ENST00000270451.5
ENST00000588537.1
ZNF581
zinc finger protein 581
chr2_-_74780176 0.95 ENST00000409549.1
LOXL3
lysyl oxidase-like 3
chr1_-_160832670 0.95 ENST00000368032.2
CD244
CD244 molecule, natural killer cell receptor 2B4
chr12_-_80084594 0.95 ENST00000548426.1
PAWR
PRKC, apoptosis, WT1, regulator
chr1_+_201617450 0.95 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr1_+_10459433 0.94 ENST00000465632.1
ENST00000460189.1
PGD
phosphogluconate dehydrogenase
chrX_-_153979315 0.94 ENST00000369575.3
ENST00000369568.4
ENST00000424127.2
GAB3
GRB2-associated binding protein 3
chr1_-_154164534 0.94 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr2_+_11295624 0.94 ENST00000402361.1
ENST00000428481.1
PQLC3
PQ loop repeat containing 3
chr11_-_64901900 0.93 ENST00000526060.1
ENST00000307289.6
ENST00000528487.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr22_-_50689786 0.92 ENST00000216271.5
HDAC10
histone deacetylase 10
chr11_-_64901978 0.92 ENST00000294256.8
ENST00000377190.3
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr3_+_69812877 0.92 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr20_+_814377 0.91 ENST00000304189.2
ENST00000381939.1
FAM110A
family with sequence similarity 110, member A
chr1_+_16084428 0.90 ENST00000510929.1
ENST00000502638.1
FBLIM1
filamin binding LIM protein 1
chr11_+_82612740 0.90 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82
chromosome 11 open reading frame 82
chr12_-_57504069 0.90 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr10_-_46089939 0.90 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of PPARG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.2 5.0 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.8 4.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.7 2.2 GO:0002818 intracellular defense response(GO:0002818)
0.7 2.2 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.6 1.9 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.6 1.8 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.6 2.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.6 3.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.5 1.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.5 5.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.5 3.0 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.5 1.5 GO:0045554 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.5 1.9 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.5 3.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.4 5.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.4 6.2 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.4 4.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4 2.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 2.0 GO:0071400 cellular response to oleic acid(GO:0071400)
0.4 9.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.4 0.8 GO:0048320 axial mesoderm formation(GO:0048320)
0.4 2.6 GO:0002254 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.4 1.5 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.4 2.2 GO:0070295 renal water absorption(GO:0070295)
0.4 1.5 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 3.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.3 1.7 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.3 2.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.3 1.0 GO:0071661 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.3 1.9 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.3 1.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.3 25.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 1.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 0.6 GO:0001300 chronological cell aging(GO:0001300)
0.3 1.2 GO:0052418 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 4.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.3 1.4 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.3 1.4 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.3 1.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 1.1 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.3 1.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 2.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.3 0.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 0.5 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.2 2.0 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 1.4 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 1.2 GO:0032796 uropod organization(GO:0032796)
0.2 1.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 2.6 GO:0070269 pyroptosis(GO:0070269)
0.2 1.8 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.9 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 3.5 GO:0001955 blood vessel maturation(GO:0001955)
0.2 2.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 1.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 1.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 3.9 GO:0060312 regulation of blood vessel remodeling(GO:0060312)
0.2 0.5 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) positive regulation of T cell extravasation(GO:2000409) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.2 1.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.2 0.8 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.2 8.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.2 1.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 2.0 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.6 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:2000563 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.8 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 3.6 GO:0015671 oxygen transport(GO:0015671)
0.1 1.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 1.2 GO:0046618 drug export(GO:0046618)
0.1 0.8 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.6 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.7 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 2.6 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0043335 protein unfolding(GO:0043335)
0.1 2.0 GO:0015816 glycine transport(GO:0015816)
0.1 0.5 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 3.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 12.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 1.3 GO:0006477 protein sulfation(GO:0006477)
0.1 0.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 4.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.4 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 1.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.7 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 1.4 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 3.4 GO:0019835 cytolysis(GO:0019835)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 1.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 3.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.6 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.8 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.9 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.7 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 1.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.5 GO:0045730 respiratory burst(GO:0045730)
0.1 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.3 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 1.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.9 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 2.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.1 12.8 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.3 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.8 GO:0007320 insemination(GO:0007320)
0.1 1.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0050668 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) positive regulation of homocysteine metabolic process(GO:0050668)
0.1 1.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 2.6 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 0.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.1 2.3 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.7 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 3.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.2 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.7 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 4.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 1.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 1.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 2.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.6 GO:0044351 macropinocytosis(GO:0044351)
0.0 2.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.6 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 4.5 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 2.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 2.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 2.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 3.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.5 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.9 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.4 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.6 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 4.0 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 2.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.7 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.7 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 1.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 10.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.7 6.1 GO:0044194 cytolytic granule(GO:0044194)
0.6 2.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 1.4 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.4 21.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 2.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.3 2.5 GO:0032010 phagolysosome(GO:0032010)
0.3 2.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 2.6 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.2 1.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 6.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 3.6 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 0.8 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.2 0.6 GO:0072563 endothelial microparticle(GO:0072563)
0.2 5.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.1 GO:0036021 endolysosome lumen(GO:0036021)
0.1 5.0 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 13.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 2.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.8 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 2.1 GO:0030897 HOPS complex(GO:0030897)
0.1 4.6 GO:0005605 basal lamina(GO:0005605)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.8 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 11.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0002133 polycystin complex(GO:0002133)
0.0 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 7.2 GO:0072562 blood microparticle(GO:0072562)
0.0 2.4 GO:0001533 cornified envelope(GO:0001533)
0.0 4.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 4.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.6 GO:0036020 endolysosome(GO:0036019) endolysosome membrane(GO:0036020)
0.0 3.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 7.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 1.9 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 5.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 27.8 GO:0005615 extracellular space(GO:0005615)
0.0 1.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 3.2 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.7 GO:0030496 midbody(GO:0030496)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
1.1 3.4 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
1.1 3.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
1.0 5.2 GO:0019770 IgG receptor activity(GO:0019770)
1.0 3.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.6 1.9 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.6 1.8 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.5 3.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.5 1.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.4 2.2 GO:0015254 glycerol channel activity(GO:0015254)
0.4 1.6 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.4 2.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.4 2.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.4 3.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.4 10.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 1.5 GO:0008518 reduced folate carrier activity(GO:0008518)
0.4 1.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.3 3.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 21.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.7 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 1.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.3 4.8 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.3 1.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.3 1.4 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.3 1.4 GO:0031711 bradykinin receptor binding(GO:0031711)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 1.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.2 1.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 1.9 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.4 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 1.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 1.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.8 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 1.2 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 0.6 GO:0004766 spermidine synthase activity(GO:0004766)
0.2 2.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 1.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 4.1 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 8.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.7 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 3.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 2.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 2.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.6 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 1.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.6 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 4.2 GO:0022829 wide pore channel activity(GO:0022829)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 2.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 21.8 GO:0003823 antigen binding(GO:0003823)
0.1 1.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.5 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 11.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 5.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 2.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 1.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 4.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.1 GO:0005123 death receptor binding(GO:0005123)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.3 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 2.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.8 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 4.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 3.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 2.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 4.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.0 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.7 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 3.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:0035529 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 9.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 5.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.5 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 3.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 3.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 10.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 5.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 6.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.4 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 5.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 4.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID ARF 3PATHWAY Arf1 pathway
0.0 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 4.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 7.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 10.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 15.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 5.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 5.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 4.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 4.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 4.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.7 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 3.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions