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Illumina Body Map 2, young vs old

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Results for PTF1A

Z-value: 0.26

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.5 pancreas associated transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PTF1Ahg19_v2_chr10_+_23481233_234812560.431.3e-02Click!

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_35721106 2.70 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr8_-_22089533 2.39 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_-_22089845 2.32 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr8_+_11351494 2.27 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr3_+_35721182 2.20 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_9129598 2.16 ENST00000535586.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_9129631 2.15 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr22_-_50523807 2.09 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_35681081 2.09 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr22_-_50523688 2.07 ENST00000450140.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523760 1.98 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_+_11351876 1.84 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr6_-_159466042 1.82 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chrX_-_13956497 1.78 ENST00000398361.3
GPM6B
glycoprotein M6B
chr1_-_9129895 1.78 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_159466136 1.61 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chrX_-_13956737 1.58 ENST00000454189.2
GPM6B
glycoprotein M6B
chr3_+_35721130 1.57 ENST00000432450.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr14_-_77737543 1.53 ENST00000298352.4
NGB
neuroglobin
chr12_-_75603482 1.53 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr2_-_239140011 1.50 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr4_-_83719983 1.47 ENST00000319540.4
SCD5
stearoyl-CoA desaturase 5
chr12_-_75603643 1.46 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr7_-_142169013 1.46 ENST00000454561.2
TRBV5-4
T cell receptor beta variable 5-4
chr3_-_193272874 1.39 ENST00000342695.4
ATP13A4
ATPase type 13A4
chr3_+_35680339 1.36 ENST00000450234.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr15_-_89764929 1.34 ENST00000268125.5
RLBP1
retinaldehyde binding protein 1
chr1_-_40782347 1.34 ENST00000417105.1
COL9A2
collagen, type IX, alpha 2
chr2_+_89196746 1.32 ENST00000390244.2
IGKV5-2
immunoglobulin kappa variable 5-2
chr4_-_87278857 1.31 ENST00000509464.1
ENST00000511167.1
MAPK10
mitogen-activated protein kinase 10
chr3_+_167453493 1.29 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr7_-_142207004 1.28 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr13_+_107029084 1.28 ENST00000444865.1
LINC00460
long intergenic non-protein coding RNA 460
chr1_-_9129735 1.26 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr4_+_40198527 1.25 ENST00000381799.5
RHOH
ras homolog family member H
chr12_+_50451331 1.24 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr11_-_83878041 1.23 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr16_+_71392616 1.21 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr14_-_24042184 1.20 ENST00000544177.1
JPH4
junctophilin 4
chr3_+_167453026 1.20 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr11_+_73357614 1.15 ENST00000536527.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_-_62996066 1.15 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr10_-_10504285 1.10 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr2_-_237412331 1.02 ENST00000418802.1
IQCA1
IQ motif containing with AAA domain 1
chr1_+_23037323 0.99 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr6_-_127780510 0.97 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr6_+_27107053 0.95 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr17_-_61778528 0.94 ENST00000584645.1
LIMD2
LIM domain containing 2
chrX_-_48216101 0.93 ENST00000298396.2
ENST00000376893.3
SSX3
synovial sarcoma, X breakpoint 3
chr12_+_1929644 0.92 ENST00000299194.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr10_-_1779663 0.91 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr22_+_23101182 0.91 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr5_+_132149017 0.90 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr9_+_33795533 0.88 ENST00000379405.3
PRSS3
protease, serine, 3
chr2_-_237416071 0.88 ENST00000309507.5
ENST00000431676.2
IQCA1
IQ motif containing with AAA domain 1
chr7_-_142099977 0.88 ENST00000390359.3
TRBV7-8
T cell receptor beta variable 7-8
chr7_-_142198049 0.84 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr11_+_56949221 0.82 ENST00000497933.1
LRRC55
leucine rich repeat containing 55
chr17_+_40996590 0.80 ENST00000253799.3
ENST00000452774.2
AOC2
amine oxidase, copper containing 2 (retina-specific)
chr11_-_45687128 0.78 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr19_+_29493456 0.76 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2
CTD-2081K17.2
chr12_+_1929421 0.75 ENST00000543818.1
LRTM2
leucine-rich repeats and transmembrane domains 2
chr1_+_26856236 0.75 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_2005126 0.75 ENST00000495347.1
PRKCZ
protein kinase C, zeta
chr16_+_89696692 0.74 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr2_-_237416181 0.74 ENST00000409907.3
IQCA1
IQ motif containing with AAA domain 1
chr12_-_10095997 0.73 ENST00000412084.1
AC091814.2
AC091814.2
chr13_+_107028897 0.70 ENST00000439790.1
ENST00000435024.1
LINC00460
long intergenic non-protein coding RNA 460
chr15_+_81225699 0.70 ENST00000560027.1
KIAA1199
KIAA1199
chr2_-_89417335 0.69 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr10_+_124739911 0.67 ENST00000405485.1
PSTK
phosphoseryl-tRNA kinase
chr1_+_228337553 0.67 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr2_+_173600514 0.67 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_90102594 0.67 ENST00000428670.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_57644952 0.66 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr11_-_1629693 0.65 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr2_+_173600565 0.64 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr8_-_9762871 0.64 ENST00000521242.1
LINC00599
long intergenic non-protein coding RNA 599
chr4_-_5990166 0.62 ENST00000324058.5
C4orf50
chromosome 4 open reading frame 50
chr2_+_85922491 0.61 ENST00000526018.1
GNLY
granulysin
chr10_+_124739964 0.60 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr6_-_24877490 0.60 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr15_+_68924327 0.60 ENST00000543950.1
CORO2B
coronin, actin binding protein, 2B
chr11_+_71276609 0.58 ENST00000398531.1
ENST00000376536.4
KRTAP5-10
keratin associated protein 5-10
chr15_+_51633826 0.56 ENST00000335449.6
GLDN
gliomedin
chr11_+_64107663 0.55 ENST00000356786.5
CCDC88B
coiled-coil domain containing 88B
chr2_-_89278535 0.55 ENST00000390247.2
IGKV3-7
immunoglobulin kappa variable 3-7 (non-functional)
chr4_-_175750364 0.55 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3
chr4_-_83719884 0.54 ENST00000282709.4
ENST00000273908.4
SCD5
stearoyl-CoA desaturase 5
chr17_-_3461092 0.54 ENST00000301365.4
ENST00000572519.1
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr17_+_67498538 0.54 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr17_+_67498396 0.52 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr1_-_114447683 0.51 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr1_-_45956822 0.51 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr1_-_45956800 0.51 ENST00000538496.1
TESK2
testis-specific kinase 2
chr1_-_231114542 0.51 ENST00000522821.1
ENST00000366661.4
ENST00000366662.4
ENST00000414259.1
ENST00000522399.1
TTC13
tetratricopeptide repeat domain 13
chr20_+_42544782 0.50 ENST00000423191.2
ENST00000372999.1
TOX2
TOX high mobility group box family member 2
chr1_+_114447763 0.50 ENST00000369563.3
DCLRE1B
DNA cross-link repair 1B
chr10_+_49892904 0.50 ENST00000360890.2
WDFY4
WDFY family member 4
chr8_-_110660975 0.50 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr17_-_36499693 0.50 ENST00000342292.4
GPR179
G protein-coupled receptor 179
chr17_-_73892992 0.49 ENST00000540128.1
ENST00000269383.3
TRIM65
tripartite motif containing 65
chr19_-_7764960 0.47 ENST00000593418.1
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr1_-_114447620 0.47 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr7_-_142251148 0.47 ENST00000390360.3
TRBV6-4
T cell receptor beta variable 6-4
chr11_-_40315640 0.46 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_+_19779686 0.46 ENST00000415784.2
ZNF101
zinc finger protein 101
chr1_-_45956868 0.46 ENST00000451835.2
TESK2
testis-specific kinase 2
chr11_+_64058758 0.44 ENST00000538767.1
KCNK4
potassium channel, subfamily K, member 4
chr9_+_107266455 0.44 ENST00000334726.2
OR13F1
olfactory receptor, family 13, subfamily F, member 1
chr1_-_205649580 0.43 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr5_-_55902050 0.42 ENST00000438651.1
AC022431.2
Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
chr5_-_75013193 0.42 ENST00000514838.2
ENST00000506164.1
ENST00000502826.1
ENST00000503835.1
ENST00000428202.2
ENST00000380475.2
POC5
POC5 centriolar protein
chr3_+_49027308 0.41 ENST00000383729.4
ENST00000343546.4
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr13_-_31736132 0.41 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr13_-_111522162 0.40 ENST00000538077.1
LINC00346
long intergenic non-protein coding RNA 346
chr13_-_31736027 0.39 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1
heat shock 105kDa/110kDa protein 1
chr3_-_69249863 0.39 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr16_-_75569068 0.39 ENST00000336257.3
ENST00000565039.1
CHST5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr19_+_54495542 0.39 ENST00000252729.2
ENST00000352529.1
CACNG6
calcium channel, voltage-dependent, gamma subunit 6
chr11_+_71249071 0.38 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr22_-_50051151 0.37 ENST00000400023.1
ENST00000444628.1
C22orf34
chromosome 22 open reading frame 34
chr12_+_112451120 0.36 ENST00000261735.3
ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr3_+_2140565 0.34 ENST00000455083.1
ENST00000418658.1
CNTN4
contactin 4
chr19_+_11670245 0.34 ENST00000585493.1
ZNF627
zinc finger protein 627
chr1_-_33647267 0.33 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr2_-_228497888 0.33 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr11_-_96123022 0.32 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr17_+_67498295 0.31 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr20_-_44937124 0.31 ENST00000537909.1
CDH22
cadherin 22, type 2
chr11_+_7597639 0.30 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_-_134305322 0.30 ENST00000276241.6
ENST00000344129.2
CXorf48
cancer/testis antigen 55
chr12_+_31079362 0.29 ENST00000545802.1
TSPAN11
tetraspanin 11
chr5_-_173217916 0.29 ENST00000523617.1
CTB-43E15.4
CTB-43E15.4
chr17_+_12692774 0.28 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr19_+_29493486 0.27 ENST00000589821.1
CTD-2081K17.2
CTD-2081K17.2
chr17_-_33415837 0.27 ENST00000414419.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr20_+_44637526 0.27 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr13_-_79979952 0.27 ENST00000438724.1
RBM26
RNA binding motif protein 26
chr11_-_1606513 0.26 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr10_+_43572475 0.26 ENST00000355710.3
ENST00000498820.1
ENST00000340058.5
RET
ret proto-oncogene
chr15_+_91446961 0.26 ENST00000559965.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr5_-_162887071 0.25 ENST00000302764.4
NUDCD2
NudC domain containing 2
chr11_-_102576537 0.25 ENST00000260229.4
MMP27
matrix metallopeptidase 27
chr3_+_2140476 0.25 ENST00000422330.1
CNTN4
contactin 4
chr17_+_79859985 0.24 ENST00000333383.7
NPB
neuropeptide B
chrX_+_15808569 0.23 ENST00000380308.3
ENST00000307771.7
ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr11_+_6806248 0.22 ENST00000307401.4
OR2AG1
olfactory receptor, family 2, subfamily AG, member 1
chr13_+_113633620 0.22 ENST00000421756.1
ENST00000375601.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_20446020 0.22 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr2_-_136288113 0.21 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr11_+_1651033 0.21 ENST00000399676.2
KRTAP5-5
keratin associated protein 5-5
chr9_-_35042824 0.21 ENST00000595331.1
FLJ00273
FLJ00273
chr19_+_17326521 0.20 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr2_-_89513402 0.20 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr22_-_50050986 0.20 ENST00000405854.1
C22orf34
chromosome 22 open reading frame 34
chr9_-_139219640 0.20 ENST00000601276.1
DKFZP434A062
HCG2022364; Putative uncharacterized protein DKFZp434A062; Uncharacterized protein
chr11_+_64052692 0.19 ENST00000377702.4
GPR137
G protein-coupled receptor 137
chr20_+_44441304 0.18 ENST00000352551.5
UBE2C
ubiquitin-conjugating enzyme E2C
chr5_+_140557371 0.18 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr8_-_145642203 0.18 ENST00000526658.1
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_-_114447412 0.18 ENST00000369567.1
ENST00000369566.3
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr14_+_70346125 0.18 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr13_-_79979919 0.18 ENST00000267229.7
RBM26
RNA binding motif protein 26
chr5_+_125800836 0.18 ENST00000511134.1
GRAMD3
GRAM domain containing 3
chr1_-_204654826 0.18 ENST00000367177.3
LRRN2
leucine rich repeat neuronal 2
chr14_+_22981834 0.17 ENST00000390507.1
TRAJ30
T cell receptor alpha joining 30
chr18_+_5238055 0.16 ENST00000582363.1
ENST00000582008.1
ENST00000580082.1
LINC00667
long intergenic non-protein coding RNA 667
chr16_-_46723066 0.16 ENST00000299138.7
VPS35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr19_-_44258733 0.16 ENST00000597586.1
ENST00000596714.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr2_+_202122826 0.15 ENST00000413726.1
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr11_+_64052266 0.15 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr9_+_99691286 0.14 ENST00000372322.3
NUTM2G
NUT family member 2G
chr20_+_18125727 0.14 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr9_+_138235095 0.14 ENST00000320778.2
C9orf62
chromosome 9 open reading frame 62
chr17_-_33416231 0.14 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr1_+_100503643 0.13 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr11_+_96123158 0.13 ENST00000332349.4
ENST00000458427.1
JRKL
jerky homolog-like (mouse)
chr5_-_162887054 0.13 ENST00000517501.1
NUDCD2
NudC domain containing 2
chr3_-_169587621 0.13 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr4_+_183370146 0.13 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr3_+_49027771 0.13 ENST00000475629.1
ENST00000444213.1
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr2_+_202122703 0.12 ENST00000447616.1
ENST00000358485.4
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr18_-_53177984 0.11 ENST00000543082.1
TCF4
transcription factor 4
chr1_-_76076759 0.11 ENST00000370855.5
SLC44A5
solute carrier family 44, member 5
chr5_+_109218883 0.11 ENST00000523446.1
AC011366.3
Uncharacterized protein
chr2_-_196933536 0.10 ENST00000312428.6
ENST00000410072.1
DNAH7
dynein, axonemal, heavy chain 7
chr20_+_54823788 0.10 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr9_-_104145795 0.10 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_+_40204538 0.10 ENST00000324379.5
ENST00000356511.2
ENST00000497370.1
ENST00000470213.1
ENST00000372835.5
ENST00000372830.1
PPIE
peptidylprolyl isomerase E (cyclophilin E)
chr11_-_130298888 0.09 ENST00000257359.6
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr17_-_3375033 0.09 ENST00000268981.5
ENST00000397168.3
ENST00000572969.1
ENST00000355380.4
ENST00000571553.1
ENST00000574797.1
ENST00000575375.1
SPATA22
spermatogenesis associated 22
chr14_-_58893832 0.09 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr7_-_100844193 0.09 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
MOGAT3
monoacylglycerol O-acyltransferase 3
chr11_+_64052454 0.09 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr7_-_152373216 0.08 ENST00000359321.1
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr7_+_141811539 0.08 ENST00000550469.2
ENST00000477922.3
RP11-1220K2.2
Putative inactive maltase-glucoamylase-like protein LOC93432
chr14_+_67656110 0.07 ENST00000524532.1
ENST00000530728.1
FAM71D
family with sequence similarity 71, member D
chr9_-_97090926 0.06 ENST00000335456.7
ENST00000253262.4
ENST00000341207.4
NUTM2F
NUT family member 2F
chr8_-_145641864 0.06 ENST00000276833.5
SLC39A4
solute carrier family 39 (zinc transporter), member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0032445 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.7 2.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 3.0 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 1.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.3 3.4 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 1.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 5.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 0.7 GO:0016999 antibiotic metabolic process(GO:0016999)
0.2 0.6 GO:0002818 intracellular defense response(GO:0002818)
0.2 1.3 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.2 1.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.2 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.4 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.4 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.8 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 1.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0007497 posterior midgut development(GO:0007497)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.5 GO:0031627 telomeric loop formation(GO:0031627) telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 4.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.7 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.5 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.8 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.3 GO:0039650 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 8.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 1.2 GO:0046710 GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.4 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 2.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.2 GO:0007602 phototransduction(GO:0007602)
0.0 1.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.7 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.7 GO:0048741 skeletal muscle fiber development(GO:0048741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 0.5 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.4 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 1.2 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 3.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.9 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 5.6 GO:0005901 caveola(GO:0005901)
0.0 7.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.2 GO:0031904 endosome lumen(GO:0031904)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.0 3.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.2 2.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 1.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 0.8 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 1.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 3.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.7 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0019863 IgE binding(GO:0019863)
0.0 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 6.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 2.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 8.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.3 GO:0030552 cAMP binding(GO:0030552)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 4.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 4.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS