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Illumina Body Map 2, young vs old

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Results for RARB

Z-value: 0.26

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Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
RARB
ENSG00000077092.14 retinoic acid receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARBhg19_v2_chr3_+_25469724_25469773-0.154.0e-01Click!

Activity profile of RARB motif

Sorted Z-values of RARB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_17721920 4.63 ENST00000295156.4
VSNL1
visinin-like 1
chr2_-_21266935 4.01 ENST00000233242.1
APOB
apolipoprotein B
chr2_+_17721937 3.89 ENST00000451533.1
VSNL1
visinin-like 1
chr16_+_20462783 3.16 ENST00000574251.1
ENST00000576361.1
ENST00000417235.2
ENST00000573854.1
ENST00000424070.1
ENST00000536134.1
ENST00000219054.6
ENST00000575690.1
ENST00000571894.1
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr11_-_116708302 3.02 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr2_-_21266816 3.02 ENST00000399256.4
APOB
apolipoprotein B
chr16_-_20587599 2.97 ENST00000566384.1
ENST00000565232.1
ENST00000567001.1
ENST00000565322.1
ENST00000569344.1
ENST00000329697.6
ENST00000414188.2
ENST00000568882.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr1_+_161190160 2.76 ENST00000594609.1
AL590714.1
Uncharacterized protein
chr17_-_26903900 2.73 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr12_-_10151773 2.72 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr9_-_104145795 2.44 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr19_-_51017127 2.36 ENST00000389208.4
ASPDH
aspartate dehydrogenase domain containing
chr11_-_116663127 2.18 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr4_-_69536346 2.16 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr4_-_100140331 2.07 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr10_-_101825151 2.00 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr12_-_323689 1.99 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr7_-_44180884 1.94 ENST00000458240.1
ENST00000223364.3
MYL7
myosin, light chain 7, regulatory
chr1_+_196946664 1.90 ENST00000367414.5
CFHR5
complement factor H-related 5
chr7_-_99381798 1.85 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr19_+_1491144 1.80 ENST00000233596.3
REEP6
receptor accessory protein 6
chr12_-_323248 1.79 ENST00000535347.1
ENST00000536824.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr11_+_121447469 1.75 ENST00000532694.1
ENST00000534286.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_+_61520075 1.72 ENST00000278836.5
MYRF
myelin regulatory factor
chr4_-_6557336 1.70 ENST00000507294.1
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr11_-_796197 1.70 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr6_+_24495067 1.60 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr18_-_70210764 1.58 ENST00000585159.1
ENST00000584764.1
CBLN2
cerebellin 2 precursor
chr12_+_57943781 1.57 ENST00000455537.2
ENST00000286452.5
KIF5A
kinesin family member 5A
chr7_-_99381884 1.49 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr1_-_112106556 1.48 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr1_-_161519682 1.44 ENST00000367969.3
ENST00000443193.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr12_+_56075330 1.42 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr5_-_74162739 1.41 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chr4_-_171011323 1.41 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
AADAT
aminoadipate aminotransferase
chr1_+_53392901 1.35 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
SCP2
sterol carrier protein 2
chr4_-_6202291 1.31 ENST00000282924.5
JAKMIP1
janus kinase and microtubule interacting protein 1
chr6_+_24495185 1.24 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chrY_-_23548246 1.24 ENST00000382764.1
CYorf17
chromosome Y open reading frame 17
chr16_-_4852915 1.23 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chrX_+_152224766 1.23 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chrX_+_102024075 1.21 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr14_+_95078714 1.19 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr5_-_147211190 1.16 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr12_+_4130143 1.08 ENST00000543206.1
RP11-320N7.2
RP11-320N7.2
chr11_-_131533462 1.08 ENST00000416725.1
AP003039.3
AP003039.3
chr16_-_10868853 1.07 ENST00000572428.1
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chr7_-_99332719 1.06 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr11_-_63381823 1.05 ENST00000323646.5
PLA2G16
phospholipase A2, group XVI
chr5_-_135290705 1.04 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr11_+_118398178 1.02 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr5_-_135290651 1.01 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_217082311 1.01 ENST00000597904.1
RP11-566E18.3
RP11-566E18.3
chr8_+_67624653 1.00 ENST00000521198.2
SGK3
serum/glucocorticoid regulated kinase family, member 3
chr11_+_63870660 1.00 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr11_-_798239 0.97 ENST00000531437.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_+_225600404 0.97 ENST00000366845.2
AC092811.1
AC092811.1
chr20_-_43729750 0.96 ENST00000537075.1
ENST00000306117.1
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr11_-_63381925 0.95 ENST00000415826.1
PLA2G16
phospholipase A2, group XVI
chr8_+_91013676 0.93 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr6_-_49430886 0.91 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr5_+_70883154 0.91 ENST00000509358.2
MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr19_-_19384055 0.90 ENST00000389363.4
TM6SF2
transmembrane 6 superfamily member 2
chr7_+_99425633 0.90 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr11_-_798305 0.89 ENST00000531514.1
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr8_-_36636676 0.89 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr2_-_152830441 0.88 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr15_+_40531243 0.88 ENST00000558055.1
ENST00000455577.2
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr7_+_73623717 0.87 ENST00000344995.5
ENST00000460943.1
LAT2
linker for activation of T cells family, member 2
chr2_+_220492116 0.86 ENST00000373760.2
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr5_-_74162605 0.85 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr16_-_1993124 0.85 ENST00000473663.1
ENST00000399753.2
ENST00000564908.1
MSRB1
methionine sulfoxide reductase B1
chr19_-_33360647 0.85 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr8_+_91013577 0.82 ENST00000220764.2
DECR1
2,4-dienoyl CoA reductase 1, mitochondrial
chr15_-_54051831 0.82 ENST00000557913.1
ENST00000360509.5
WDR72
WD repeat domain 72
chr16_-_1993260 0.81 ENST00000361871.3
MSRB1
methionine sulfoxide reductase B1
chr1_+_174669653 0.78 ENST00000325589.5
RABGAP1L
RAB GTPase activating protein 1-like
chr14_+_89290965 0.78 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8
tetratricopeptide repeat domain 8
chrM_+_3299 0.77 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr6_+_31554779 0.77 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr3_-_121448791 0.77 ENST00000489400.1
GOLGB1
golgin B1
chr17_-_56358287 0.76 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr21_-_35284635 0.75 ENST00000429238.1
AP000304.12
AP000304.12
chr7_-_127671674 0.72 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr12_-_81763184 0.72 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr19_+_55174400 0.72 ENST00000430952.2
ENST00000391734.3
ENST00000391733.3
ENST00000434286.1
LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr17_-_41277317 0.72 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
BRCA1
breast cancer 1, early onset
chr10_-_103599591 0.71 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr11_+_73359936 0.71 ENST00000542389.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_56100757 0.69 ENST00000433279.1
AL353698.1
Uncharacterized protein
chr18_-_74839891 0.69 ENST00000581878.1
MBP
myelin basic protein
chr7_-_144533074 0.69 ENST00000360057.3
ENST00000378099.3
TPK1
thiamin pyrophosphokinase 1
chr7_+_73624327 0.68 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
LAT2
linker for activation of T cells family, member 2
chr10_-_43762329 0.68 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr18_-_24765248 0.66 ENST00000580774.1
ENST00000284224.8
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr4_-_168155300 0.64 ENST00000541637.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr22_-_37976082 0.64 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr7_-_141401951 0.64 ENST00000536163.1
KIAA1147
KIAA1147
chr1_+_78245303 0.63 ENST00000370791.3
ENST00000443751.2
FAM73A
family with sequence similarity 73, member A
chrX_+_23682379 0.63 ENST00000379349.1
PRDX4
peroxiredoxin 4
chr17_-_41277370 0.63 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
BRCA1
breast cancer 1, early onset
chr1_+_43803475 0.63 ENST00000372470.3
ENST00000413998.2
MPL
myeloproliferative leukemia virus oncogene
chr1_+_28206150 0.62 ENST00000456990.1
THEMIS2
thymocyte selection associated family member 2
chr4_+_70146217 0.62 ENST00000335568.5
ENST00000511240.1
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28
chr2_+_119981384 0.62 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP3
STEAP family member 3, metalloreductase
chr10_-_27530997 0.61 ENST00000375901.1
ENST00000412279.1
ENST00000375905.4
ACBD5
acyl-CoA binding domain containing 5
chr9_+_34957477 0.60 ENST00000544237.1
KIAA1045
KIAA1045
chr19_-_54692132 0.60 ENST00000449249.1
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr5_-_55412774 0.60 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr6_+_2988199 0.60 ENST00000450238.1
ENST00000445000.1
ENST00000426637.1
LINC01011
NQO2
long intergenic non-protein coding RNA 1011
NAD(P)H dehydrogenase, quinone 2
chr19_+_46531127 0.60 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr1_+_17944832 0.59 ENST00000167825.4
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_-_110052302 0.59 ENST00000369864.4
ENST00000369862.1
AMIGO1
adhesion molecule with Ig-like domain 1
chr12_+_28605426 0.58 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr6_+_31554962 0.58 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr18_-_44336754 0.58 ENST00000538168.1
ENST00000536490.1
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr6_+_31554612 0.57 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr15_+_32888449 0.56 ENST00000426622.2
GOLGA8N
golgin A8 family, member N
chr19_-_22193706 0.56 ENST00000597040.1
ZNF208
zinc finger protein 208
chr11_+_73360024 0.56 ENST00000540431.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_-_3521518 0.56 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr19_+_13228917 0.56 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_-_152830479 0.55 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr15_+_29211570 0.54 ENST00000558804.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr5_+_125935960 0.53 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr12_+_56862301 0.53 ENST00000338146.5
SPRYD4
SPRY domain containing 4
chr12_-_120241187 0.52 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr18_-_24722995 0.52 ENST00000581714.1
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr14_+_104710541 0.51 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr17_+_8316442 0.51 ENST00000582812.1
NDEL1
nudE neurodevelopment protein 1-like 1
chr1_-_150979333 0.50 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr19_-_23869999 0.50 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr19_-_23185947 0.50 ENST00000594710.1
ZNF728
zinc finger protein 728
chr14_+_103566665 0.50 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr1_+_59775752 0.50 ENST00000371212.1
FGGY
FGGY carbohydrate kinase domain containing
chr12_+_49658855 0.50 ENST00000549183.1
TUBA1C
tubulin, alpha 1c
chrX_-_119709637 0.49 ENST00000404115.3
CUL4B
cullin 4B
chr11_+_85566422 0.49 ENST00000342404.3
CCDC83
coiled-coil domain containing 83
chr6_+_160327974 0.49 ENST00000252660.4
MAS1
MAS1 oncogene
chr3_-_110612059 0.47 ENST00000485473.1
RP11-553A10.1
Uncharacterized protein
chr5_-_133968529 0.46 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr20_-_3185279 0.46 ENST00000354488.3
ENST00000380201.2
DDRGK1
DDRGK domain containing 1
chr3_-_195938256 0.45 ENST00000296326.3
ZDHHC19
zinc finger, DHHC-type containing 19
chr1_+_26872324 0.45 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_+_7118755 0.45 ENST00000433456.1
RNF144A
ring finger protein 144A
chr1_-_160313025 0.45 ENST00000368069.3
ENST00000241704.7
COPA
coatomer protein complex, subunit alpha
chr2_-_3606206 0.44 ENST00000315212.3
RNASEH1
ribonuclease H1
chr3_-_64009658 0.44 ENST00000394431.2
PSMD6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr18_-_19283649 0.44 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr3_-_122283079 0.44 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr19_-_8567505 0.43 ENST00000600262.1
PRAM1
PML-RARA regulated adaptor molecule 1
chr8_+_48873453 0.43 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr16_+_2533020 0.43 ENST00000562105.1
TBC1D24
TBC1 domain family, member 24
chr16_+_57673207 0.43 ENST00000564783.1
ENST00000564729.1
ENST00000565976.1
ENST00000566508.1
ENST00000544297.1
GPR56
G protein-coupled receptor 56
chr2_+_11679963 0.42 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr6_+_88106840 0.41 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr10_-_61899124 0.41 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_10534944 0.40 ENST00000356607.4
ENST00000538836.1
ENST00000491661.2
PEX14
peroxisomal biogenesis factor 14
chr8_-_27462822 0.40 ENST00000522098.1
CLU
clusterin
chr4_-_141075330 0.40 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chr7_-_123198284 0.40 ENST00000355749.2
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr3_-_122283100 0.39 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr6_+_49431073 0.39 ENST00000335783.3
CENPQ
centromere protein Q
chr10_-_70287231 0.39 ENST00000609923.1
SLC25A16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr1_+_16330723 0.38 ENST00000329454.2
C1orf64
chromosome 1 open reading frame 64
chr6_+_24667257 0.37 ENST00000537591.1
ENST00000230048.4
ACOT13
acyl-CoA thioesterase 13
chr8_-_141774467 0.37 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr19_-_46142637 0.37 ENST00000590043.1
ENST00000589876.1
EML2
echinoderm microtubule associated protein like 2
chr13_+_73302047 0.36 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
BORA
bora, aurora kinase A activator
chr11_-_122931881 0.36 ENST00000526110.1
ENST00000227378.3
HSPA8
heat shock 70kDa protein 8
chrX_+_55246771 0.34 ENST00000289619.5
ENST00000374955.3
PAGE5
P antigen family, member 5 (prostate associated)
chr20_-_5485166 0.34 ENST00000589201.1
ENST00000379053.4
LINC00654
long intergenic non-protein coding RNA 654
chr2_+_74361599 0.34 ENST00000401851.1
MGC10955
MGC10955
chr1_+_155278539 0.34 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chrX_-_53461288 0.33 ENST00000375298.4
ENST00000375304.5
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr20_+_33462745 0.33 ENST00000488172.1
ACSS2
acyl-CoA synthetase short-chain family member 2
chr16_-_18923035 0.32 ENST00000563836.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr1_+_120049826 0.32 ENST00000369413.3
ENST00000235547.6
ENST00000528909.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr6_+_3982909 0.32 ENST00000356722.3
C6ORF50
C6ORF50
chr7_-_6098770 0.32 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr19_+_21688366 0.32 ENST00000358491.4
ENST00000597078.1
ZNF429
zinc finger protein 429
chr11_+_69240431 0.31 ENST00000545202.1
AP000439.1
AP000439.1
chr10_+_11784360 0.31 ENST00000379215.4
ENST00000420401.1
ECHDC3
enoyl CoA hydratase domain containing 3
chr16_-_46649905 0.31 ENST00000569702.1
SHCBP1
SHC SH2-domain binding protein 1
chr14_+_22964877 0.30 ENST00000390494.1
TRAJ43
T cell receptor alpha joining 43
chr11_-_62476694 0.30 ENST00000524862.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr1_-_86861660 0.29 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr1_-_173572181 0.29 ENST00000536496.1
ENST00000367714.3
SLC9C2
solute carrier family 9, member C2 (putative)
chr7_+_73624276 0.28 ENST00000475494.1
ENST00000398475.1
LAT2
linker for activation of T cells family, member 2
chr3_-_47554791 0.28 ENST00000449409.1
ENST00000414236.1
ENST00000444760.1
ENST00000439305.1
ELP6
elongator acetyltransferase complex subunit 6
chr3_-_109056419 0.28 ENST00000335658.6
DPPA4
developmental pluripotency associated 4
chr7_-_155601766 0.28 ENST00000430104.1
SHH
sonic hedgehog
chr5_+_80597453 0.27 ENST00000438268.2
ZCCHC9
zinc finger, CCHC domain containing 9
chrX_-_128782722 0.27 ENST00000427399.1
APLN
apelin
chr1_+_120049809 0.26 ENST00000531340.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr19_+_38880695 0.26 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr19_-_58204128 0.26 ENST00000597520.1
AC004017.1
Uncharacterized protein
chr17_+_78518617 0.25 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr22_-_43036607 0.25 ENST00000505920.1
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr22_-_43398442 0.25 ENST00000422336.1
PACSIN2
protein kinase C and casein kinase substrate in neurons 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.8 3.3 GO:0009822 alkaloid catabolic process(GO:0009822)
0.8 2.4 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.8 3.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.6 1.7 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 1.3 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.4 2.2 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.4 2.8 GO:0006540 glutamate decarboxylation to succinate(GO:0006540) gamma-aminobutyric acid catabolic process(GO:0009450)
0.4 2.0 GO:0030070 insulin processing(GO:0030070)
0.3 3.2 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.3 1.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 1.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.2 3.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.2 0.6 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 2.4 GO:0019530 taurine metabolic process(GO:0019530)
0.2 2.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.2 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 1.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 2.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 0.7 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 0.9 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.9 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 2.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 8.3 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1 0.7 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.5 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 1.7 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.5 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.1 0.7 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 2.4 GO:0006069 ethanol oxidation(GO:0006069)
0.1 3.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.9 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.8 GO:0050893 sensory processing(GO:0050893)
0.1 0.3 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.9 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.3 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.1 2.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.8 GO:0001878 response to yeast(GO:0001878)
0.1 0.6 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.4 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.5 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 2.6 GO:0030220 platelet formation(GO:0030220)
0.1 1.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.7 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 1.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.8 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 1.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.6 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.3 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:0019860 uracil metabolic process(GO:0019860) intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.4 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 2.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 4.2 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.8 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.5 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 2.0 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.7 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 10.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 0.9 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.2 3.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.7 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.7 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 3.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 1.8 GO:0042629 mast cell granule(GO:0042629)
0.0 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 1.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 3.0 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 2.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 13.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.2 GO:0035473 lipase binding(GO:0035473)
0.8 3.3 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.8 3.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.5 2.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.5 3.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.5 6.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.5 1.4 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.4 1.3 GO:0070538 oleic acid binding(GO:0070538)
0.4 1.8 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.3 3.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.2 1.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 2.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 2.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.2 1.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.5 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 0.9 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 2.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.5 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.6 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.9 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 1.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.5 GO:0019864 IgG binding(GO:0019864)
0.1 2.0 GO:0070330 aromatase activity(GO:0070330)
0.1 1.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.7 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 2.8 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 7.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 2.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 2.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 3.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide