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Illumina Body Map 2, young vs old

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Results for SCRT1_SCRT2

Z-value: 0.21

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
SCRT1
ENSG00000170616.9 scratch family transcriptional repressor 1
SCRT2
ENSG00000215397.3 scratch family transcriptional repressor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg19_v2_chr8_-_145559943_1455599430.541.5e-03Click!
SCRT2hg19_v2_chr20_-_656823_6569020.411.9e-02Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_41258786 10.60 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr6_+_121756809 7.48 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr17_+_37784749 6.52 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr1_+_16083098 5.97 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr1_+_16083154 5.94 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr3_+_181429704 5.91 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr15_-_30114231 5.77 ENST00000356107.6
ENST00000545208.2
TJP1
tight junction protein 1
chr3_+_16216210 5.55 ENST00000437509.1
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr1_+_16083123 5.43 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chr7_-_122526499 5.35 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr4_+_41540160 4.94 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr12_-_15374328 4.92 ENST00000537647.1
RERG
RAS-like, estrogen-regulated, growth inhibitor
chrX_-_134232630 4.78 ENST00000535837.1
ENST00000433425.2
LINC00087
long intergenic non-protein coding RNA 87
chr3_+_16216137 4.74 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr15_-_30113676 4.70 ENST00000400011.2
TJP1
tight junction protein 1
chr19_-_7990991 4.43 ENST00000318978.4
CTXN1
cortexin 1
chr7_+_20370746 4.40 ENST00000222573.4
ITGB8
integrin, beta 8
chr17_+_53343577 3.76 ENST00000573945.1
HLF
hepatic leukemia factor
chr2_+_18059906 3.72 ENST00000304101.4
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr5_+_15500280 3.69 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr8_+_75736761 3.62 ENST00000260113.2
PI15
peptidase inhibitor 15
chr4_-_5890145 3.56 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr4_-_110223799 3.50 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1
collagen, type XXV, alpha 1
chr13_+_39261224 3.30 ENST00000280481.7
FREM2
FRAS1 related extracellular matrix protein 2
chrX_-_70150939 3.20 ENST00000374299.3
ENST00000298085.4
SLC7A3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr8_+_98881268 3.18 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr19_-_409134 3.02 ENST00000332235.6
C2CD4C
C2 calcium-dependent domain containing 4C
chrX_-_151143140 3.02 ENST00000393914.3
ENST00000370328.3
ENST00000370325.1
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr13_+_96743093 2.99 ENST00000376705.2
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr12_-_33049690 2.91 ENST00000070846.6
ENST00000340811.4
PKP2
plakophilin 2
chr8_+_120220561 2.91 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_122526411 2.89 ENST00000449022.2
CADPS2
Ca++-dependent secretion activator 2
chr3_-_147124547 2.83 ENST00000491672.1
ENST00000383075.3
ZIC4
Zic family member 4
chr7_-_122526799 2.76 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr1_-_95392635 2.71 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr9_+_69650263 2.69 ENST00000322495.3
AL445665.1
Protein LOC100996643
chr15_+_63889577 2.63 ENST00000534939.1
ENST00000539570.3
FBXL22
F-box and leucine-rich repeat protein 22
chr9_-_35658007 2.55 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr4_+_165675197 2.55 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr2_-_241759622 2.55 ENST00000320389.7
ENST00000498729.2
KIF1A
kinesin family member 1A
chr2_-_224467093 2.54 ENST00000305409.2
SCG2
secretogranin II
chr15_+_63889552 2.47 ENST00000360587.2
FBXL22
F-box and leucine-rich repeat protein 22
chr11_-_111794446 2.40 ENST00000527950.1
CRYAB
crystallin, alpha B
chr14_+_23775971 2.38 ENST00000250405.5
BCL2L2
BCL2-like 2
chr2_+_101437487 2.38 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr2_+_173600671 2.38 ENST00000409036.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chrX_-_55057403 2.37 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2
aminolevulinate, delta-, synthase 2
chrX_-_107975917 2.35 ENST00000563887.1
RP6-24A23.6
Uncharacterized protein
chr18_+_61616510 2.29 ENST00000408945.3
HMSD
histocompatibility (minor) serpin domain containing
chr2_-_119916459 2.27 ENST00000272520.3
C1QL2
complement component 1, q subcomponent-like 2
chr10_+_6779326 2.24 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr15_+_43885252 2.19 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr1_+_156308403 2.18 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr11_-_8739566 2.16 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr19_-_46974741 2.14 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1
chr2_-_178753465 2.14 ENST00000389683.3
PDE11A
phosphodiesterase 11A
chr1_-_204135450 2.14 ENST00000272190.8
ENST00000367195.2
REN
renin
chrX_-_99986494 2.13 ENST00000372989.1
ENST00000455616.1
ENST00000454200.2
ENST00000276141.6
SYTL4
synaptotagmin-like 4
chr1_+_156308245 2.12 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr18_-_10791648 2.02 ENST00000583325.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr18_+_74962505 2.01 ENST00000299727.3
GALR1
galanin receptor 1
chrX_-_99987088 1.98 ENST00000372981.1
ENST00000263033.5
SYTL4
synaptotagmin-like 4
chr15_+_43985084 1.98 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr4_-_141348789 1.96 ENST00000414773.1
CLGN
calmegin
chr19_-_46974664 1.95 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr3_-_62861012 1.95 ENST00000357948.3
ENST00000383710.4
CADPS
Ca++-dependent secretion activator
chr4_-_89619386 1.90 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr4_-_110223523 1.87 ENST00000399127.1
COL25A1
collagen, type XXV, alpha 1
chrX_-_31284974 1.84 ENST00000378702.4
DMD
dystrophin
chr14_-_24042184 1.82 ENST00000544177.1
JPH4
junctophilin 4
chr5_+_32710736 1.82 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr11_+_27062272 1.81 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_-_147211226 1.80 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr13_+_58206655 1.79 ENST00000377918.3
PCDH17
protocadherin 17
chr5_-_35938674 1.78 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL
calcyphosine-like
chr12_+_129028500 1.78 ENST00000315208.8
TMEM132C
transmembrane protein 132C
chr12_+_81471816 1.76 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr2_-_110962544 1.75 ENST00000355301.4
ENST00000445609.2
ENST00000417665.1
ENST00000418527.1
ENST00000316534.4
ENST00000393272.3
NPHP1
nephronophthisis 1 (juvenile)
chr12_-_71148413 1.74 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr17_-_32484313 1.73 ENST00000359872.6
ASIC2
acid-sensing (proton-gated) ion channel 2
chr11_-_117748138 1.72 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chrX_-_31285018 1.72 ENST00000361471.4
DMD
dystrophin
chr3_-_62860878 1.71 ENST00000283269.9
CADPS
Ca++-dependent secretion activator
chr20_-_43977055 1.71 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr12_-_71148357 1.71 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_215256467 1.65 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chrX_-_31285042 1.65 ENST00000378680.2
ENST00000378723.3
DMD
dystrophin
chr1_+_220701456 1.64 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr12_-_71003568 1.60 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_-_179754556 1.59 ENST00000263962.8
PEX5L
peroxisomal biogenesis factor 5-like
chr11_-_61584233 1.57 ENST00000491310.1
FADS1
fatty acid desaturase 1
chr18_+_32073839 1.54 ENST00000590412.1
DTNA
dystrobrevin, alpha
chr3_+_133465228 1.54 ENST00000482271.1
ENST00000264998.3
TF
transferrin
chr8_-_139509065 1.51 ENST00000395297.1
FAM135B
family with sequence similarity 135, member B
chr4_-_83483395 1.50 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr2_+_173600565 1.46 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr20_-_23402028 1.45 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chr2_+_173600514 1.45 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr7_+_94536898 1.42 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr2_-_224467002 1.41 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr15_-_76352069 1.39 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr13_-_25746416 1.34 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr1_-_94312706 1.33 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr2_-_180726232 1.30 ENST00000410066.1
ZNF385B
zinc finger protein 385B
chr14_+_32964258 1.29 ENST00000556638.1
AKAP6
A kinase (PRKA) anchor protein 6
chr2_+_24397930 1.29 ENST00000295150.3
FAM228A
family with sequence similarity 228, member A
chr15_-_44486632 1.28 ENST00000484674.1
FRMD5
FERM domain containing 5
chr3_-_147124307 1.26 ENST00000463250.1
ZIC4
Zic family member 4
chr10_+_24528108 1.25 ENST00000438429.1
KIAA1217
KIAA1217
chr19_-_11373128 1.24 ENST00000294618.7
DOCK6
dedicator of cytokinesis 6
chr11_-_117747607 1.24 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr3_-_143567262 1.24 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr11_-_30038490 1.24 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr11_-_117747434 1.23 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr5_+_125759140 1.23 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr3_+_107096188 1.21 ENST00000261058.1
CCDC54
coiled-coil domain containing 54
chr3_+_167453026 1.20 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_+_125758813 1.19 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr11_+_61583968 1.16 ENST00000517839.1
FADS2
fatty acid desaturase 2
chr1_-_21044489 1.16 ENST00000247986.2
KIF17
kinesin family member 17
chr5_+_125758865 1.16 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr3_-_79816965 1.15 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_+_140430979 1.12 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr2_-_175870085 1.11 ENST00000409156.3
CHN1
chimerin 1
chr19_-_51220176 1.10 ENST00000359082.3
ENST00000293441.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chrX_+_51636629 1.10 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr4_-_52904425 1.09 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr3_+_10857885 1.09 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr5_+_148651469 1.08 ENST00000515000.1
AFAP1L1
actin filament associated protein 1-like 1
chr1_-_52456352 1.06 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr3_+_167453493 1.05 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chrX_+_55744228 1.05 ENST00000262850.7
RRAGB
Ras-related GTP binding B
chr19_-_49250054 1.04 ENST00000602105.1
ENST00000332955.2
IZUMO1
izumo sperm-egg fusion 1
chrX_-_51812268 1.04 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B
melanoma antigen family D, 4B
chr16_+_2198604 1.03 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr10_+_3109695 1.02 ENST00000381125.4
PFKP
phosphofructokinase, platelet
chr4_-_90757364 1.02 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_61583721 1.02 ENST00000257261.6
FADS2
fatty acid desaturase 2
chr17_-_45056606 1.01 ENST00000322329.3
RPRML
reprimo-like
chr7_+_73242069 1.00 ENST00000435050.1
CLDN4
claudin 4
chr6_+_71122974 1.00 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr6_+_69345166 1.00 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr16_-_53537105 0.99 ENST00000568596.1
ENST00000570004.1
ENST00000564497.1
ENST00000300245.4
ENST00000394657.7
AKTIP
AKT interacting protein
chr4_+_165675269 0.98 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr13_+_20268547 0.98 ENST00000601204.1
AL354808.2
AL354808.2
chr11_-_117747327 0.96 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr5_-_73936544 0.96 ENST00000509127.2
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr5_+_173763250 0.96 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr8_-_33330595 0.95 ENST00000524021.1
ENST00000335589.3
FUT10
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr1_+_24645807 0.95 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_-_73936451 0.95 ENST00000537006.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr11_-_8816375 0.93 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr16_-_84076241 0.93 ENST00000568178.1
SLC38A8
solute carrier family 38, member 8
chr1_-_162838551 0.93 ENST00000367910.1
ENST00000367912.2
ENST00000367911.2
C1orf110
chromosome 1 open reading frame 110
chrX_+_151806637 0.92 ENST00000370306.2
GABRQ
gamma-aminobutyric acid (GABA) A receptor, theta
chr5_+_148651409 0.91 ENST00000296721.4
AFAP1L1
actin filament associated protein 1-like 1
chr10_+_24497704 0.91 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr10_+_24498060 0.91 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr17_-_36105009 0.90 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr15_+_43885799 0.89 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr2_-_237172988 0.89 ENST00000409749.3
ENST00000430053.1
ASB18
ankyrin repeat and SOCS box containing 18
chr17_-_15496722 0.88 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr7_+_6713376 0.88 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
AC073343.1
Uncharacterized protein
chr11_+_69455855 0.87 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr7_-_50628745 0.87 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_+_73242490 0.87 ENST00000431918.1
CLDN4
claudin 4
chr11_-_26593677 0.87 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_-_67197760 0.86 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr12_-_21810726 0.85 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr1_+_24645865 0.85 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr2_+_223289208 0.85 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr9_+_125703282 0.84 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr16_+_2039946 0.84 ENST00000248121.2
ENST00000568896.1
SYNGR3
synaptogyrin 3
chr19_-_58609570 0.84 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr3_-_55515202 0.83 ENST00000482079.1
WNT5A
wingless-type MMTV integration site family, member 5A
chr11_+_107650219 0.82 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr10_-_116164239 0.82 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
AFAP1L2
actin filament associated protein 1-like 2
chr8_-_110988070 0.82 ENST00000524391.1
KCNV1
potassium channel, subfamily V, member 1
chr14_+_66578299 0.81 ENST00000554187.1
ENST00000556662.1
ENST00000556291.1
ENST00000557723.1
ENST00000557050.1
RP11-783L4.1
RP11-783L4.1
chr12_+_101988627 0.81 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chrX_+_51928002 0.81 ENST00000375626.3
MAGED4
melanoma antigen family D, 4
chr1_+_150245099 0.79 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr3_-_179754733 0.78 ENST00000472994.1
PEX5L
peroxisomal biogenesis factor 5-like
chrX_-_153141302 0.77 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1CAM
L1 cell adhesion molecule
chr9_+_99212403 0.76 ENST00000375251.3
ENST00000375249.4
HABP4
hyaluronan binding protein 4
chr7_+_94536514 0.76 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr1_-_183622442 0.76 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr12_-_21810765 0.75 ENST00000450584.1
ENST00000350669.1
LDHB
lactate dehydrogenase B
chr9_+_140125209 0.75 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr14_+_67707826 0.75 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr1_-_219615984 0.72 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr11_-_71159380 0.72 ENST00000525346.1
ENST00000531364.1
ENST00000529990.1
ENST00000527316.1
ENST00000407721.2
DHCR7
7-dehydrocholesterol reductase
chr21_+_25801041 0.70 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr3_-_179754706 0.70 ENST00000465751.1
ENST00000467460.1
PEX5L
peroxisomal biogenesis factor 5-like
chr1_-_212588157 0.70 ENST00000261455.4
ENST00000535273.1
TMEM206
transmembrane protein 206
chr6_-_34113856 0.70 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr11_+_61583772 0.68 ENST00000522639.1
ENST00000522056.1
FADS2
fatty acid desaturase 2
chr3_+_26664291 0.68 ENST00000396641.2
LRRC3B
leucine rich repeat containing 3B
chr3_+_145782358 0.67 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr11_+_65779283 0.67 ENST00000312134.2
CST6
cystatin E/M

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0007412 axon target recognition(GO:0007412)
2.6 10.5 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.9 7.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.6 14.7 GO:1990504 dense core granule exocytosis(GO:1990504)
1.2 3.6 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.0 3.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.8 17.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.7 3.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.6 2.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 6.8 GO:0001714 endodermal cell fate specification(GO:0001714)
0.6 1.8 GO:1990709 presynaptic active zone organization(GO:1990709)
0.6 6.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.6 1.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.5 3.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.5 3.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 1.4 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.5 3.2 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.4 5.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 3.7 GO:0010265 SCF complex assembly(GO:0010265)
0.4 1.1 GO:0050894 determination of affect(GO:0050894)
0.4 5.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 2.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.3 1.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 2.0 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 1.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.3 1.9 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3 0.9 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.3 1.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.3 1.5 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 1.8 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 1.7 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 2.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 3.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.2 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 1.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.8 GO:0060809 chemoattraction of serotonergic neuron axon(GO:0036517) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.2 1.0 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.6 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 3.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 2.4 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 0.7 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 1.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 1.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.0 GO:1990539 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.4 GO:0006173 dADP biosynthetic process(GO:0006173)
0.1 1.8 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 4.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.9 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.7 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.4 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.4 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.1 2.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 2.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 2.4 GO:0051775 response to redox state(GO:0051775)
0.1 1.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.8 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 3.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.4 GO:0003409 optic cup structural organization(GO:0003409)
0.1 2.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 10.3 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 2.9 GO:0045056 transcytosis(GO:0045056)
0.1 0.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.1 1.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 1.6 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.8 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 5.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 1.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 2.0 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 0.9 GO:0070141 response to UV-A(GO:0070141)
0.1 2.5 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 5.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 1.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 1.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.8 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 1.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.6 GO:0007498 mesoderm development(GO:0007498)
0.0 0.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 1.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 3.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475) mRNA methylation(GO:0080009)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 1.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.0 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.9 GO:0008347 glial cell migration(GO:0008347)
0.0 0.6 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 8.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 4.0 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.8 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 3.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 1.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.0 GO:0035272 exocrine system development(GO:0035272)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.8 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 4.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.4 5.2 GO:0016013 syntrophin complex(GO:0016013)
0.4 17.9 GO:0005921 gap junction(GO:0005921)
0.3 1.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.3 2.6 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 13.1 GO:1904115 axon cytoplasm(GO:1904115)
0.2 3.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.7 GO:0044305 calyx of Held(GO:0044305)
0.1 5.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.9 GO:0031045 dense core granule(GO:0031045)
0.1 1.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 3.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 17.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.4 GO:0043219 lateral loop(GO:0043219)
0.1 8.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.4 GO:0032982 myosin filament(GO:0032982)
0.1 10.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.9 GO:0030057 desmosome(GO:0030057)
0.1 1.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 7.6 GO:0005581 collagen trimer(GO:0005581)
0.0 2.0 GO:0071437 invadopodium(GO:0071437)
0.0 1.7 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 6.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 15.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.9 GO:0098793 presynapse(GO:0098793)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.3 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 2.8 GO:0042383 sarcolemma(GO:0042383)
0.0 3.8 GO:0030496 midbody(GO:0030496)
0.0 1.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 2.1 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.3 6.5 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.8 7.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.8 2.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.7 3.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.7 4.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 20.9 GO:0031005 filamin binding(GO:0031005)
0.5 1.6 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.5 1.5 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.5 2.9 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.5 1.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 3.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 1.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.4 1.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 3.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 1.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 2.0 GO:0004966 galanin receptor activity(GO:0004966)
0.3 2.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 10.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 1.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.2 1.8 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 0.6 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 0.8 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 2.0 GO:0004111 creatine kinase activity(GO:0004111)
0.2 5.9 GO:0035198 miRNA binding(GO:0035198)
0.2 0.6 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 5.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 3.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.9 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 5.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 5.5 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.8 GO:0051400 BH domain binding(GO:0051400)
0.1 1.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.4 GO:0031432 titin binding(GO:0031432)
0.1 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 5.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 5.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 4.9 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 4.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 5.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 4.3 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 3.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 4.1 GO:0051087 chaperone binding(GO:0051087)
0.0 9.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0031420 alkali metal ion binding(GO:0031420)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 5.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 2.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 11.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 7.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 4.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 7.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 17.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 7.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 4.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 5.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 5.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 6.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 4.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.7 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 3.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 4.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 4.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids