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Illumina Body Map 2, young vs old

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Results for SOX1

Z-value: 0.28

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.3 SRY-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg19_v2_chr13_+_112721913_1127219130.019.5e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_12058961 7.95 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr16_+_12059050 6.85 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr14_+_22356029 3.85 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr14_-_25078864 3.79 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr14_+_22689792 3.54 ENST00000390462.1
TRAV35
T cell receptor alpha variable 35
chr12_+_9980069 3.35 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr7_-_36634181 2.73 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr12_+_9980113 2.69 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr22_-_30662828 2.31 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr7_+_142000747 2.22 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr12_-_7848364 2.20 ENST00000329913.3
GDF3
growth differentiation factor 3
chr16_+_12059091 2.13 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr6_-_130543958 1.99 ENST00000437477.2
ENST00000439090.2
SAMD3
sterile alpha motif domain containing 3
chr7_-_142176790 1.87 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr18_-_67629015 1.76 ENST00000579496.1
CD226
CD226 molecule
chr14_+_22508822 1.71 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr4_-_48116540 1.62 ENST00000506073.1
TXK
TXK tyrosine kinase
chr14_+_22970526 1.62 ENST00000390498.1
TRAJ39
T cell receptor alpha joining 39
chr11_-_47400032 1.61 ENST00000533968.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr9_-_13432977 1.60 ENST00000605459.1
RP11-536O18.2
RP11-536O18.2
chr14_+_23009190 1.57 ENST00000390532.1
TRAJ5
T cell receptor alpha joining 5
chr11_-_47399942 1.55 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr11_-_47400078 1.50 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr11_-_47400062 1.46 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_-_10607084 1.43 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr2_+_87808725 1.41 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr7_-_139756791 1.34 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr4_+_154622652 1.32 ENST00000260010.6
TLR2
toll-like receptor 2
chr17_+_34391625 1.31 ENST00000004921.3
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr19_+_55385682 1.22 ENST00000391726.3
FCAR
Fc fragment of IgA, receptor for
chr1_+_174769006 1.21 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr12_+_75874460 1.14 ENST00000266659.3
GLIPR1
GLI pathogenesis-related 1
chr3_-_107596910 1.09 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr14_+_21249200 1.09 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr8_+_53207015 1.08 ENST00000522228.1
RP11-1023P17.2
RP11-1023P17.2
chr11_-_104827425 1.08 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr18_-_56985776 1.06 ENST00000587244.1
CPLX4
complexin 4
chr14_+_38033252 1.02 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr6_+_130742231 0.99 ENST00000545622.1
TMEM200A
transmembrane protein 200A
chr5_+_135383008 0.95 ENST00000508767.1
ENST00000604555.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_+_24232918 0.93 ENST00000406420.3
ENST00000338315.4
MFSD2B
major facilitator superfamily domain containing 2B
chr9_-_123638633 0.92 ENST00000456291.1
PHF19
PHD finger protein 19
chr12_+_93096619 0.81 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr13_+_49280951 0.78 ENST00000282018.3
CYSLTR2
cysteinyl leukotriene receptor 2
chr12_-_10151773 0.74 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr12_-_10605929 0.70 ENST00000347831.5
ENST00000359151.3
KLRC1
killer cell lectin-like receptor subfamily C, member 1
chr17_-_29624343 0.70 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr14_-_89878369 0.68 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr17_-_39646116 0.68 ENST00000328119.6
KRT36
keratin 36
chr2_+_102615416 0.67 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr12_-_110434096 0.66 ENST00000320063.9
ENST00000457474.2
ENST00000547815.1
ENST00000361006.5
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr1_-_86848760 0.66 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr4_-_122686261 0.64 ENST00000337677.5
TMEM155
transmembrane protein 155
chr5_-_54988559 0.62 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr11_-_111649015 0.62 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr11_-_6790286 0.62 ENST00000338569.2
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr11_-_123756334 0.61 ENST00000528595.1
ENST00000375026.2
TMEM225
transmembrane protein 225
chr10_-_45803286 0.60 ENST00000536058.1
OR13A1
olfactory receptor, family 13, subfamily A, member 1
chr19_+_21324863 0.60 ENST00000598331.1
ZNF431
zinc finger protein 431
chr11_-_78052923 0.58 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr17_+_75181292 0.57 ENST00000431431.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr19_-_6057282 0.57 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr1_-_52499443 0.54 ENST00000371614.1
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr21_-_16126181 0.53 ENST00000455253.2
AF127936.3
AF127936.3
chr1_-_200379129 0.51 ENST00000367353.1
ZNF281
zinc finger protein 281
chr7_-_76955563 0.51 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr12_+_57810198 0.51 ENST00000598001.1
AC126614.1
HCG1818482; Uncharacterized protein
chr17_+_74729060 0.50 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr14_+_22951993 0.50 ENST00000390485.1
TRAJ53
T cell receptor alpha joining 53
chr1_+_144811943 0.49 ENST00000281815.8
NBPF9
neuroblastoma breakpoint family, member 9
chr14_+_62164340 0.46 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr8_-_49533521 0.46 ENST00000523038.1
RP11-567J20.1
RP11-567J20.1
chr11_+_125496619 0.46 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr7_-_105029812 0.44 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr7_+_36450169 0.44 ENST00000428612.1
ANLN
anillin, actin binding protein
chr11_+_125496400 0.43 ENST00000524737.1
CHEK1
checkpoint kinase 1
chr1_+_148560843 0.42 ENST00000442702.2
ENST00000369187.3
NBPF15
neuroblastoma breakpoint family, member 15
chr6_-_15548591 0.41 ENST00000509674.1
DTNBP1
dystrobrevin binding protein 1
chr22_-_17302589 0.37 ENST00000331428.5
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr10_-_45802907 0.36 ENST00000374401.2
OR13A1
olfactory receptor, family 13, subfamily A, member 1
chr1_-_112106556 0.36 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr4_-_74486109 0.34 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr20_+_31805131 0.34 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr10_+_15085895 0.33 ENST00000378228.3
OLAH
oleoyl-ACP hydrolase
chr5_-_60411762 0.31 ENST00000594278.1
AC008498.1
AC008498.1
chr9_-_107299137 0.31 ENST00000374781.2
OR13C3
olfactory receptor, family 13, subfamily C, member 3
chr17_-_38821373 0.30 ENST00000394052.3
KRT222
keratin 222
chr18_+_21719018 0.30 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr1_+_206516200 0.30 ENST00000295713.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_127174845 0.29 ENST00000540814.1
ENST00000541065.1
ENST00000541769.1
RP11-407A16.3
RP11-407A16.4
RP11-407A16.3
RP11-407A16.4
chr7_-_110174754 0.29 ENST00000435466.1
AC003088.1
AC003088.1
chr19_+_35842445 0.28 ENST00000246553.2
FFAR1
free fatty acid receptor 1
chr19_+_17830051 0.27 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr12_+_55248289 0.26 ENST00000308796.6
MUCL1
mucin-like 1
chr11_-_5255861 0.26 ENST00000380299.3
HBD
hemoglobin, delta
chr19_+_49588690 0.26 ENST00000221448.5
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr5_+_147698550 0.26 ENST00000597116.1
AC091948.1
Uncharacterized protein
chr17_+_33448593 0.26 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr1_-_200379180 0.25 ENST00000294740.3
ZNF281
zinc finger protein 281
chr11_-_112131312 0.25 ENST00000527122.1
C11orf34
placenta expressed transcript 1
chr4_-_74486347 0.24 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr3_-_16524357 0.24 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr15_+_42565393 0.24 ENST00000561871.1
GANC
glucosidase, alpha; neutral C
chr1_-_112106578 0.23 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr3_+_136676707 0.23 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chrX_-_115594160 0.22 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr12_-_110434183 0.22 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chrX_-_11129229 0.22 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr19_+_49588677 0.21 ENST00000598984.1
ENST00000598441.1
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr18_-_51751132 0.20 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr8_-_86290333 0.20 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
CA1
carbonic anhydrase I
chr3_+_136676851 0.19 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr12_+_7456880 0.19 ENST00000399422.4
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr2_+_234296792 0.19 ENST00000409813.3
DGKD
diacylglycerol kinase, delta 130kDa
chr1_-_200379104 0.18 ENST00000367352.3
ZNF281
zinc finger protein 281
chr19_+_21324827 0.18 ENST00000600692.1
ENST00000599296.1
ENST00000594425.1
ENST00000311048.7
ZNF431
zinc finger protein 431
chr20_+_49575342 0.17 ENST00000244051.1
MOCS3
molybdenum cofactor synthesis 3
chr16_-_18937072 0.17 ENST00000569122.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr11_-_5255696 0.16 ENST00000292901.3
ENST00000417377.1
HBD
hemoglobin, delta
chr14_+_22951276 0.16 ENST00000390484.1
TRAJ54
T cell receptor alpha joining 54
chr19_-_10491234 0.15 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr12_-_65146636 0.15 ENST00000418919.2
GNS
glucosamine (N-acetyl)-6-sulfatase
chr11_+_125496124 0.14 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr11_-_112131583 0.14 ENST00000338832.2
C11orf34
placenta expressed transcript 1
chr4_-_74486217 0.13 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_74949033 0.13 ENST00000416014.2
LRRC53
leucine rich repeat containing 53
chr1_+_12806141 0.13 ENST00000288048.5
C1orf158
chromosome 1 open reading frame 158
chr6_+_149539767 0.13 ENST00000606202.1
ENST00000536230.1
ENST00000445901.1
TAB2
RP1-111D6.3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
RP1-111D6.3
chr3_-_44519131 0.12 ENST00000425708.2
ENST00000396077.2
ZNF445
zinc finger protein 445
chr8_-_102181718 0.12 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chr10_+_47894572 0.11 ENST00000355876.5
FAM21B
family with sequence similarity 21, member B
chr2_+_171036635 0.11 ENST00000484338.2
ENST00000334231.6
MYO3B
myosin IIIB
chr2_+_171034646 0.10 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr19_+_3762703 0.10 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chrX_+_129040122 0.10 ENST00000394422.3
ENST00000371051.5
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr19_-_10491130 0.10 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr11_+_55029628 0.10 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr11_-_18062872 0.09 ENST00000250018.2
TPH1
tryptophan hydroxylase 1
chr14_+_62462541 0.09 ENST00000430451.2
SYT16
synaptotagmin XVI
chr13_+_109248500 0.09 ENST00000356711.2
MYO16
myosin XVI
chr21_-_23058648 0.08 ENST00000416182.1
AF241725.6
AF241725.6
chr15_+_57540230 0.06 ENST00000559703.1
TCF12
transcription factor 12
chr1_+_202789394 0.04 ENST00000330493.5
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr8_+_137059264 0.04 ENST00000502901.2
ENST00000523150.1
RP11-149P24.1
RP11-149P24.1
chr11_-_57177586 0.03 ENST00000529411.1
RP11-872D17.8
Uncharacterized protein
chr1_+_24646263 0.03 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_184020811 0.02 ENST00000361641.1
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr5_+_158654712 0.02 ENST00000520323.1
CTB-11I22.2
CTB-11I22.2
chr16_-_52107814 0.02 ENST00000562818.1
C16orf97
chromosome 16 open reading frame 97
chr3_+_132316081 0.02 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr4_+_156680153 0.00 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 1.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 1.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.3 2.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 2.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 1.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 1.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 0.7 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 17.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.4 GO:1904172 septin ring assembly(GO:0000921) septin ring organization(GO:0031106) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.1 0.8 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.4 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 1.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.5 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.3 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 3.8 GO:0019835 cytolysis(GO:0019835)
0.1 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.6 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 1.3 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 1.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 1.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 6.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.5 6.1 GO:0051525 NFAT protein binding(GO:0051525)
0.5 6.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.4 2.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 1.2 GO:0019862 IgA binding(GO:0019862)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.8 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 1.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 2.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0004536 deoxyribonuclease activity(GO:0004536)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID IL3 PATHWAY IL3-mediated signaling events
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 6.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)