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Illumina Body Map 2, young vs old

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Results for SOX4

Z-value: 0.10

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Transcription factors associated with SOX4

Gene Symbol Gene ID Gene Info
SOX4
ENSG00000124766.4 SRY-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX4hg19_v2_chr6_+_21593972_215940710.327.8e-02Click!

Activity profile of SOX4 motif

Sorted Z-values of SOX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27219849 3.32 ENST00000396344.4
HOXA10
homeobox A10
chr6_-_139613269 3.07 ENST00000358430.3
TXLNB
taxilin beta
chr14_+_75746664 2.70 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_75746781 2.28 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_+_55248289 2.07 ENST00000308796.6
MUCL1
mucin-like 1
chr5_+_102200948 2.02 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_-_39424961 1.90 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr18_+_3449821 1.82 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr5_-_141338627 1.78 ENST00000231484.3
PCDH12
protocadherin 12
chr10_+_6244829 1.75 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr22_+_40322595 1.68 ENST00000420971.1
ENST00000544756.1
GRAP2
GRB2-related adaptor protein 2
chr13_-_110959478 1.57 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr18_+_3450161 1.55 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr7_+_139528952 1.54 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr5_-_39425290 1.50 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_-_37899323 1.49 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr5_-_39425222 1.45 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr10_-_105845536 1.45 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr6_+_139456226 1.45 ENST00000367658.2
HECA
headcase homolog (Drosophila)
chr9_+_112852477 1.43 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr5_-_141338377 1.40 ENST00000510041.1
PCDH12
protocadherin 12
chr4_+_102734967 1.40 ENST00000444316.2
BANK1
B-cell scaffold protein with ankyrin repeats 1
chr2_-_85641162 1.40 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr13_-_41593425 1.39 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_-_10830463 1.39 ENST00000527419.1
ENST00000530211.1
ENST00000530702.1
ENST00000524932.1
ENST00000532570.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr22_+_40322623 1.33 ENST00000399090.2
GRAP2
GRB2-related adaptor protein 2
chr21_+_30671690 1.31 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr4_+_40201954 1.30 ENST00000511121.1
RHOH
ras homolog family member H
chr19_+_10765614 1.29 ENST00000589283.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr4_-_109090106 1.28 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chrX_+_12993336 1.26 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr18_+_6729698 1.26 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr5_-_39425068 1.26 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr11_-_6677018 1.26 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr10_+_11047259 1.20 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr3_+_111260856 1.18 ENST00000352690.4
CD96
CD96 molecule
chr12_-_10251603 1.17 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr20_-_39317868 1.16 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr7_+_115850547 1.16 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
TES
testis derived transcript (3 LIM domains)
chr1_+_28844778 1.15 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr10_+_17272608 1.15 ENST00000421459.2
VIM
vimentin
chr9_+_101705893 1.15 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr14_-_61124977 1.14 ENST00000554986.1
SIX1
SIX homeobox 1
chr15_+_41136216 1.14 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr9_-_117150243 1.13 ENST00000374088.3
AKNA
AT-hook transcription factor
chr15_+_41136734 1.13 ENST00000568580.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_+_111260954 1.13 ENST00000283285.5
CD96
CD96 molecule
chr2_+_201981663 1.09 ENST00000433445.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_111260980 1.09 ENST00000438817.2
CD96
CD96 molecule
chr15_+_91416092 1.09 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr18_+_6729725 1.08 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr10_-_105845674 1.08 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr17_+_67498538 1.07 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_-_50649192 1.06 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr2_+_223536428 1.06 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr10_+_11207088 1.06 ENST00000608830.1
CELF2
CUGBP, Elav-like family member 2
chr2_-_1748214 1.05 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr6_-_133055815 1.04 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr16_+_54964740 1.04 ENST00000394636.4
IRX5
iroquois homeobox 5
chr12_-_10251576 1.03 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr1_-_93645818 1.02 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr9_-_74383302 1.01 ENST00000377066.5
TMEM2
transmembrane protein 2
chr17_-_10372875 1.00 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr14_-_23791484 1.00 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr1_+_209602771 0.99 ENST00000440276.1
MIR205HG
MIR205 host gene (non-protein coding)
chr12_-_10251539 0.99 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr15_-_70390213 0.98 ENST00000557997.1
ENST00000317509.8
ENST00000442299.2
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr12_+_95611536 0.96 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_167487808 0.96 ENST00000392122.3
CD247
CD247 molecule
chr1_-_167487758 0.96 ENST00000362089.5
CD247
CD247 molecule
chr15_+_41136263 0.95 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr19_+_56111680 0.93 ENST00000301073.3
ZNF524
zinc finger protein 524
chr19_+_10765699 0.92 ENST00000590009.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr20_-_13971255 0.92 ENST00000284951.5
ENST00000378072.5
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr12_-_76879852 0.91 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr11_-_71810258 0.90 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr11_-_10829851 0.90 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr15_-_70390191 0.89 ENST00000559191.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr7_-_38305279 0.87 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr2_+_54684327 0.86 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr20_-_56284816 0.85 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr10_+_11206925 0.85 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr17_+_67498295 0.84 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr14_+_24439148 0.82 ENST00000543805.1
ENST00000534993.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr4_-_109089573 0.82 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr12_+_95611569 0.82 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr9_-_117150303 0.82 ENST00000312033.3
AKNA
AT-hook transcription factor
chr4_+_78078304 0.81 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2
cyclin G2
chrX_+_12993202 0.81 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chrX_-_153599578 0.80 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chrX_+_9433289 0.80 ENST00000422314.1
TBL1X
transducin (beta)-like 1X-linked
chr3_-_186262166 0.78 ENST00000307944.5
CRYGS
crystallin, gamma S
chr14_+_22987424 0.78 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr12_+_8666126 0.78 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr20_+_30598231 0.78 ENST00000300415.8
ENST00000262659.8
CCM2L
cerebral cavernous malformation 2-like
chr22_-_31688431 0.77 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chrX_-_2847366 0.77 ENST00000381154.1
ARSD
arylsulfatase D
chr15_+_41136369 0.77 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr13_+_110958124 0.76 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr16_+_21608525 0.76 ENST00000567404.1
METTL9
methyltransferase like 9
chr2_+_36923933 0.76 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT
vitrin
chr3_-_128207349 0.75 ENST00000487848.1
GATA2
GATA binding protein 2
chr7_-_84122033 0.73 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr15_+_81293254 0.73 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr5_+_102201509 0.73 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr9_+_124088860 0.72 ENST00000373806.1
GSN
gelsolin
chr3_+_50649302 0.72 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr7_-_27219632 0.72 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr22_-_31688381 0.72 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr2_+_235346970 0.71 ENST00000418025.1
AC097713.3
AC097713.3
chr4_+_2819883 0.70 ENST00000511747.1
ENST00000503393.2
SH3BP2
SH3-domain binding protein 2
chr8_-_6420777 0.70 ENST00000415216.1
ANGPT2
angiopoietin 2
chr12_-_10282681 0.69 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr3_+_141105235 0.69 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr9_-_131940526 0.69 ENST00000372491.2
IER5L
immediate early response 5-like
chr12_+_95611516 0.68 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr8_-_6420759 0.67 ENST00000523120.1
ANGPT2
angiopoietin 2
chrX_-_135962923 0.67 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr3_-_134092561 0.67 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr5_-_175964366 0.66 ENST00000274811.4
RNF44
ring finger protein 44
chr11_+_5711010 0.66 ENST00000454828.1
TRIM22
tripartite motif containing 22
chr1_+_66458072 0.65 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_156052354 0.65 ENST00000368301.2
LMNA
lamin A/C
chr8_-_116504448 0.65 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr17_-_38928414 0.65 ENST00000335552.4
KRT26
keratin 26
chr14_-_73493784 0.65 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr1_+_93645314 0.64 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr7_-_42276612 0.64 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr7_-_92855762 0.64 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr12_-_10282836 0.63 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr2_-_227050079 0.63 ENST00000423838.1
AC068138.1
AC068138.1
chr2_-_165697717 0.62 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr1_+_40840320 0.62 ENST00000372708.1
SMAP2
small ArfGAP2
chr10_+_11207438 0.62 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chrX_-_135962876 0.62 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr7_-_148725733 0.61 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr1_+_185703513 0.61 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr14_-_73493825 0.60 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr1_-_155880672 0.59 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr10_+_11207485 0.59 ENST00000537122.1
CELF2
CUGBP, Elav-like family member 2
chr8_-_6420930 0.59 ENST00000325203.5
ANGPT2
angiopoietin 2
chr4_-_69111401 0.59 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr2_+_36923830 0.59 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr16_-_73082274 0.58 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr15_+_75940218 0.58 ENST00000308527.5
SNX33
sorting nexin 33
chr8_+_61822605 0.58 ENST00000526936.1
AC022182.1
AC022182.1
chr8_-_6420565 0.57 ENST00000338312.6
ANGPT2
angiopoietin 2
chr6_-_168468082 0.56 ENST00000537786.1
FRMD1
FERM domain containing 1
chr15_-_72564906 0.55 ENST00000566844.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr4_+_78079450 0.54 ENST00000395640.1
ENST00000512918.1
CCNG2
cyclin G2
chr13_-_39612176 0.54 ENST00000352251.3
ENST00000350125.3
PROSER1
proline and serine rich 1
chr12_-_10282742 0.54 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr7_-_148581360 0.53 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr14_+_22982921 0.53 ENST00000390508.1
TRAJ29
T cell receptor alpha joining 29
chr1_-_153940097 0.53 ENST00000413622.1
ENST00000310483.6
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr8_-_16043780 0.53 ENST00000445506.2
MSR1
macrophage scavenger receptor 1
chr19_+_1249869 0.53 ENST00000591446.2
MIDN
midnolin
chr4_+_78079570 0.53 ENST00000509972.1
CCNG2
cyclin G2
chr12_+_93963590 0.51 ENST00000340600.2
SOCS2
suppressor of cytokine signaling 2
chr7_+_141408153 0.50 ENST00000397541.2
WEE2
WEE1 homolog 2 (S. pombe)
chr4_+_71263599 0.50 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr2_+_36923901 0.50 ENST00000457137.2
VIT
vitrin
chr1_-_152297679 0.49 ENST00000368799.1
FLG
filaggrin
chr11_+_113930955 0.49 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr5_+_150816595 0.49 ENST00000520111.1
ENST00000520701.1
ENST00000429484.2
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr12_+_69004619 0.49 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B
RAP1B, member of RAS oncogene family
chr5_-_135701164 0.49 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr7_-_148725544 0.48 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chr13_+_39612442 0.47 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr17_+_67498396 0.47 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_208423891 0.46 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr15_+_63335899 0.46 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr7_-_148581251 0.45 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr16_-_85617170 0.45 ENST00000602862.1
RP11-118F19.1
RP11-118F19.1
chr1_+_28261533 0.45 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_108231101 0.45 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr2_-_37501692 0.45 ENST00000443977.1
PRKD3
protein kinase D3
chr12_+_8849773 0.44 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr9_-_74979420 0.44 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr5_+_102201430 0.44 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr18_+_7946839 0.43 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr1_+_153940713 0.43 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4
cAMP responsive element binding protein 3-like 4
chr1_+_25664408 0.43 ENST00000374358.4
TMEM50A
transmembrane protein 50A
chr11_+_57531292 0.43 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr4_+_90033968 0.43 ENST00000317005.2
TIGD2
tigger transposable element derived 2
chr15_+_41136586 0.43 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr7_-_105926058 0.43 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr12_-_95611149 0.43 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr16_+_30406423 0.42 ENST00000524644.1
ZNF48
zinc finger protein 48
chr3_-_3152031 0.42 ENST00000383846.1
ENST00000427088.1
ENST00000446632.2
ENST00000438560.1
IL5RA
interleukin 5 receptor, alpha
chr15_+_78730531 0.42 ENST00000258886.8
IREB2
iron-responsive element binding protein 2
chr10_-_91102410 0.42 ENST00000282673.4
LIPA
lipase A, lysosomal acid, cholesterol esterase
chr2_-_20425158 0.42 ENST00000381150.1
SDC1
syndecan 1
chr5_+_67586465 0.41 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_153940346 0.40 ENST00000405694.3
ENST00000449724.1
ENST00000368607.3
ENST00000271889.4
CREB3L4
cAMP responsive element binding protein 3-like 4
chr14_-_57960456 0.39 ENST00000534126.1
ENST00000422976.2
C14orf105
chromosome 14 open reading frame 105
chr11_-_85430088 0.39 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr15_+_78730622 0.39 ENST00000560440.1
IREB2
iron-responsive element binding protein 2
chr6_-_27440837 0.38 ENST00000211936.6
ZNF184
zinc finger protein 184
chr17_+_9066252 0.38 ENST00000436734.1
NTN1
netrin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
1.0 6.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.6 2.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.6 2.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 5.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 3.2 GO:0018032 protein amidation(GO:0018032)
0.5 2.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 1.3 GO:0003192 mitral valve formation(GO:0003192)
0.4 1.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 1.2 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 1.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.3 1.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.3 2.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 0.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 2.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 1.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.6 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.8 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.2 0.7 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 1.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 4.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 0.5 GO:0035038 female pronucleus assembly(GO:0035038)
0.2 0.9 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.7 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.4 GO:0048627 myoblast development(GO:0048627)
0.1 0.8 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 1.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 1.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.1 0.4 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 1.9 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 3.7 GO:0060065 uterus development(GO:0060065)
0.1 1.3 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.9 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 4.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.5 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 1.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 2.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488) anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0030421 defecation(GO:0030421)
0.0 1.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.8 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 1.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 3.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0090287 regulation of cellular response to growth factor stimulus(GO:0090287)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 2.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.8 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.7 GO:0070206 protein trimerization(GO:0070206)
0.0 2.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 2.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 1.1 GO:0001960 negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.1 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 5.0 GO:0035976 AP1 complex(GO:0035976)
0.3 1.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 3.5 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.2 1.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.2 0.5 GO:0036457 keratohyalin granule(GO:0036457)
0.2 2.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.9 GO:0032437 cuticular plate(GO:0032437)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 1.4 GO:0090543 Flemming body(GO:0090543)
0.1 0.9 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 1.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.0 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.0 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 2.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.5 1.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 1.5 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 0.8 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 1.7 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2 1.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 6.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.6 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.0 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 1.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.2 1.2 GO:1990254 keratin filament binding(GO:1990254)
0.2 1.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 1.0 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 1.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 2.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 5.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.7 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.0 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 4.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.5 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 1.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 4.8 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 3.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 2.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 6.0 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 3.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 3.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 9.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 2.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 4.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 4.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 6.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 2.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 3.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle