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Illumina Body Map 2, young vs old

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Results for SOX5

Z-value: 0.13

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
SOX5
ENSG00000134532.11 SRY-box transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX5hg19_v2_chr12_-_24103841_241038800.318.6e-02Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_110958124 3.42 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr10_+_24528108 3.27 ENST00000438429.1
KIAA1217
KIAA1217
chr14_-_92414294 3.27 ENST00000554468.1
FBLN5
fibulin 5
chr7_+_15728003 2.87 ENST00000442176.1
AC005550.4
AC005550.4
chr14_-_92414055 2.76 ENST00000342058.4
FBLN5
fibulin 5
chr17_-_10452929 2.75 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr12_-_8815404 2.69 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr12_-_6233828 2.57 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chrX_+_135251783 2.41 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr7_-_83824449 2.31 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_135252050 2.25 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chrX_+_135251835 2.25 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_-_102874330 2.21 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr14_-_23904861 2.08 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chrX_+_99839799 2.07 ENST00000373031.4
TNMD
tenomodulin
chr14_-_92413727 2.05 ENST00000267620.10
FBLN5
fibulin 5
chr3_+_112930306 2.01 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr12_-_111358372 1.98 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr15_+_49715449 1.94 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr12_-_8815477 1.93 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr3_+_89156674 1.86 ENST00000336596.2
EPHA3
EPH receptor A3
chr7_-_27205136 1.81 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr7_-_16921601 1.77 ENST00000402239.3
ENST00000310398.2
ENST00000414935.1
AGR3
anterior gradient 3
chr1_+_185703513 1.73 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr8_+_144295067 1.71 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr3_+_112929850 1.61 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr7_-_7575477 1.59 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr3_-_73483055 1.57 ENST00000479530.1
PDZRN3
PDZ domain containing ring finger 3
chr12_-_102874378 1.56 ENST00000456098.1
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_1666108 1.56 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_92413353 1.52 ENST00000556154.1
FBLN5
fibulin 5
chr17_-_39041479 1.50 ENST00000167588.3
KRT20
keratin 20
chr6_-_46048116 1.47 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chrX_+_15525426 1.43 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr13_-_28545276 1.43 ENST00000381020.7
CDX2
caudal type homeobox 2
chr2_-_188312971 1.40 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr12_-_102874416 1.40 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr21_-_39870339 1.36 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr12_-_102872317 1.36 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr7_-_83824169 1.35 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr17_-_39743139 1.34 ENST00000167586.6
KRT14
keratin 14
chr5_-_158526756 1.31 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr9_-_124989804 1.30 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr7_+_134576317 1.29 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr3_+_112930387 1.29 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr12_+_60058458 1.28 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr5_-_158526693 1.28 ENST00000380654.4
EBF1
early B-cell factor 1
chr3_+_189507523 1.27 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr4_-_186732048 1.27 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr4_-_101439148 1.27 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN
endomucin
chr18_-_52989217 1.26 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_81771806 1.26 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr15_+_49715293 1.25 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr3_+_112930373 1.25 ENST00000498710.1
BOC
BOC cell adhesion associated, oncogene regulated
chr12_-_16758835 1.22 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_189507432 1.22 ENST00000354600.5
TP63
tumor protein p63
chr12_-_16758873 1.22 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_89156799 1.20 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr4_-_101439242 1.19 ENST00000296420.4
EMCN
endomucin
chr12_+_52306113 1.17 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr6_-_139613269 1.15 ENST00000358430.3
TXLNB
taxilin beta
chr7_+_134576151 1.15 ENST00000393118.2
CALD1
caldesmon 1
chr3_+_189349162 1.15 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr15_-_41166414 1.14 ENST00000220507.4
RHOV
ras homolog family member V
chr12_+_53443963 1.13 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr10_+_52750930 1.12 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr7_+_134551583 1.10 ENST00000435928.1
CALD1
caldesmon 1
chr18_-_53177984 1.09 ENST00000543082.1
TCF4
transcription factor 4
chr10_-_116444371 1.09 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr12_+_52445191 1.08 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr12_+_53443680 1.08 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr16_-_11375179 1.08 ENST00000312511.3
PRM1
protamine 1
chr13_+_73629107 1.07 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr4_+_165675197 1.04 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr12_-_24715376 1.03 ENST00000446891.2
ENST00000429944.2
RP11-444D3.1
RP11-444D3.1
chr5_-_138780159 1.03 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr12_-_16759440 1.02 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_68864330 1.01 ENST00000288368.4
PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr21_+_35552978 0.97 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr3_-_65583561 0.95 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr18_-_52989525 0.94 ENST00000457482.3
TCF4
transcription factor 4
chr10_+_52751010 0.94 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr1_+_153232160 0.94 ENST00000368742.3
LOR
loricrin
chr7_+_30960915 0.93 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr4_-_65275100 0.93 ENST00000509536.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr4_+_41614909 0.92 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr3_+_181429704 0.92 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr5_-_39462390 0.91 ENST00000511792.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_+_41614720 0.90 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr9_-_14314518 0.90 ENST00000397581.2
NFIB
nuclear factor I/B
chr9_-_14314566 0.89 ENST00000397579.2
NFIB
nuclear factor I/B
chrX_-_50557014 0.88 ENST00000376020.2
SHROOM4
shroom family member 4
chr12_-_71031185 0.88 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr8_-_93115445 0.87 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_50557302 0.85 ENST00000289292.7
SHROOM4
shroom family member 4
chr12_-_102874102 0.85 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr10_+_35415978 0.85 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM
cAMP responsive element modulator
chr10_-_13523073 0.84 ENST00000440282.1
BEND7
BEN domain containing 7
chr6_+_12290586 0.83 ENST00000379375.5
EDN1
endothelin 1
chr17_-_46703826 0.82 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr17_-_46671323 0.81 ENST00000239151.5
HOXB5
homeobox B5
chr7_+_28448995 0.81 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr6_+_126070726 0.80 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr12_-_24715478 0.79 ENST00000456299.2
ENST00000540811.1
RP11-444D3.1
RP11-444D3.1
chrX_-_17878827 0.77 ENST00000360011.1
RAI2
retinoic acid induced 2
chr10_+_35415719 0.77 ENST00000474362.1
ENST00000374721.3
CREM
cAMP responsive element modulator
chr10_+_35416090 0.77 ENST00000354759.3
CREM
cAMP responsive element modulator
chr11_+_46402744 0.76 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_+_173115520 0.75 ENST00000413821.1
NLGN1
neuroligin 1
chr11_+_46402583 0.74 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_99594948 0.73 ENST00000471562.1
ENST00000495625.2
FILIP1L
filamin A interacting protein 1-like
chr12_-_71003568 0.73 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr10_+_63661053 0.73 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr5_-_38595498 0.72 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr7_-_131241361 0.72 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr11_+_131781290 0.72 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr3_-_8686479 0.71 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr3_+_173116225 0.70 ENST00000457714.1
NLGN1
neuroligin 1
chr2_-_230787879 0.69 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr22_-_36236265 0.69 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr17_-_73505961 0.68 ENST00000433559.2
CASKIN2
CASK interacting protein 2
chr2_-_192711968 0.67 ENST00000304141.4
SDPR
serum deprivation response
chr14_+_37126765 0.66 ENST00000402703.2
PAX9
paired box 9
chr17_-_41910505 0.66 ENST00000398389.4
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr9_+_27109133 0.66 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr1_-_151119087 0.65 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr3_-_52486841 0.63 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr12_-_71031220 0.63 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_-_157198860 0.63 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr18_+_56532100 0.63 ENST00000588456.1
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr3_-_99595037 0.63 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr4_-_186732892 0.62 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_2938044 0.61 ENST00000378404.2
ACTRT2
actin-related protein T2
chr1_-_232651312 0.61 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_+_164529004 0.60 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr15_+_90319557 0.60 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr14_-_89883412 0.60 ENST00000557258.1
FOXN3
forkhead box N3
chr8_-_93115508 0.59 ENST00000518832.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_164528866 0.58 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr12_-_11508520 0.58 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr4_+_113970772 0.58 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr1_+_61547405 0.58 ENST00000371189.4
NFIA
nuclear factor I/A
chr15_+_71228826 0.57 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr9_+_27109440 0.57 ENST00000519080.1
TEK
TEK tyrosine kinase, endothelial
chr10_-_13570533 0.57 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr12_-_91451758 0.56 ENST00000266719.3
KERA
keratocan
chr7_+_114055052 0.55 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr8_+_103563792 0.55 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr20_-_61002584 0.55 ENST00000252998.1
RBBP8NL
RBBP8 N-terminal like
chr8_-_33424636 0.54 ENST00000256257.1
RNF122
ring finger protein 122
chr1_-_39395165 0.54 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr8_-_72274355 0.54 ENST00000388741.2
EYA1
eyes absent homolog 1 (Drosophila)
chrY_+_15016013 0.54 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr18_+_42260861 0.53 ENST00000282030.5
SETBP1
SET binding protein 1
chr11_+_110001723 0.53 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr18_+_3451646 0.53 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1
TGFB-induced factor homeobox 1
chr16_-_73093597 0.53 ENST00000397992.5
ZFHX3
zinc finger homeobox 3
chr4_-_65275162 0.53 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr22_+_38093005 0.52 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr11_-_89224638 0.52 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr10_+_35416223 0.51 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr11_-_72852320 0.51 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr10_+_11207088 0.51 ENST00000608830.1
CELF2
CUGBP, Elav-like family member 2
chr3_-_123339418 0.50 ENST00000583087.1
MYLK
myosin light chain kinase
chr4_+_42895284 0.50 ENST00000399770.2
GRXCR1
glutaredoxin, cysteine rich 1
chr7_+_111846741 0.49 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
ZNF277
zinc finger protein 277
chr1_+_231297798 0.49 ENST00000444294.3
TRIM67
tripartite motif containing 67
chr16_+_1128781 0.48 ENST00000293897.4
ENST00000562758.1
SSTR5
somatostatin receptor 5
chr9_+_27109392 0.48 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr1_-_36906474 0.48 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr3_-_114173654 0.48 ENST00000482689.1
ZBTB20
zinc finger and BTB domain containing 20
chr5_-_88120151 0.47 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr3_-_192635943 0.46 ENST00000392452.2
MB21D2
Mab-21 domain containing 2
chr12_+_78359999 0.46 ENST00000550503.1
NAV3
neuron navigator 3
chr12_-_65090329 0.45 ENST00000594966.1
AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
chr3_-_46904946 0.44 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_+_37894179 0.44 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr1_+_228337553 0.44 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr4_-_184241927 0.43 ENST00000323319.5
CLDN22
claudin 22
chr20_+_17207636 0.43 ENST00000262545.2
PCSK2
proprotein convertase subtilisin/kexin type 2
chr15_+_78556428 0.43 ENST00000394855.3
ENST00000489435.2
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr2_-_97536490 0.42 ENST00000449330.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr10_+_11206925 0.42 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr3_-_46904918 0.42 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr11_+_111807863 0.41 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr4_-_186732241 0.41 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr12_+_49761147 0.41 ENST00000549298.1
SPATS2
spermatogenesis associated, serine-rich 2
chr20_+_17207665 0.40 ENST00000536609.1
PCSK2
proprotein convertase subtilisin/kexin type 2
chr1_-_119543994 0.40 ENST00000439394.1
ENST00000449439.1
RP4-712E4.1
RP4-712E4.2
RP4-712E4.1
RP4-712E4.2
chr6_+_138699042 0.39 ENST00000573100.1
RP3-422G23.4
Uncharacterized protein
chr7_+_106810165 0.39 ENST00000468401.1
ENST00000497535.1
ENST00000485846.1
HBP1
HMG-box transcription factor 1
chr3_-_141747439 0.38 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_+_46402482 0.38 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_123339343 0.38 ENST00000578202.1
MYLK
myosin light chain kinase
chr2_-_208030295 0.38 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_-_24770632 0.38 ENST00000596413.1
AL353583.1
AL353583.1
chr8_+_26435915 0.38 ENST00000523027.1
DPYSL2
dihydropyrimidinase-like 2
chr15_-_34610962 0.37 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr12_+_27398584 0.37 ENST00000543246.1
STK38L
serine/threonine kinase 38 like
chr6_+_89790459 0.35 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.4 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.1 3.2 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.9 3.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.9 3.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.8 3.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.7 9.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.5 2.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.4 1.8 GO:0030185 nitric oxide transport(GO:0030185)
0.4 1.4 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.3 1.9 GO:0030421 defecation(GO:0030421)
0.3 2.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.3 2.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 1.6 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 3.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 1.7 GO:0071503 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.2 1.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 1.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 1.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.2 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.2 0.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 2.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 6.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 2.7 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.8 GO:0030070 insulin processing(GO:0030070)
0.2 1.3 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.6 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 0.9 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 1.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 2.1 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 3.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.4 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.6 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 1.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 5.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.5 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 1.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 1.5 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 1.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 6.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.9 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 1.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.4 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.7 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.3 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 1.5 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.9 GO:0070997 neuron death(GO:0070997)
0.1 0.2 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 2.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0008038 neuron recognition(GO:0008038)
0.0 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 1.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.3 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.6 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.6 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 2.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 3.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.1 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.1 GO:0050890 cognition(GO:0050890)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.4 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.9 9.6 GO:0071953 elastic fiber(GO:0071953)
0.4 3.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 2.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 0.9 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 3.5 GO:0030478 actin cap(GO:0030478)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 4.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.6 GO:0097124 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.1 2.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 5.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.7 GO:0016460 myosin II complex(GO:0016460)
0.1 0.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.6 GO:0043203 axon hillock(GO:0043203)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 3.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.8 GO:0045178 basal part of cell(GO:0045178)
0.0 10.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 10.5 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 1.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.3 1.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 0.9 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 3.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.7 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.2 1.7 GO:0035473 lipase binding(GO:0035473)
0.2 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.3 GO:1990254 keratin filament binding(GO:1990254)
0.2 3.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.9 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 1.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 3.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 7.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0031013 troponin I binding(GO:0031013)
0.1 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 4.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 3.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 2.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.7 GO:0035198 miRNA binding(GO:0035198)
0.1 1.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 9.8 GO:0005178 integrin binding(GO:0005178)
0.0 5.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.0 6.6 GO:0044325 ion channel binding(GO:0044325)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 6.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 9.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 5.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 5.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 15.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 3.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 3.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 8.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 7.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 5.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 2.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 3.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.4 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)