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Illumina Body Map 2, young vs old

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Results for SOX6

Z-value: 0.04

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_16430440-0.402.5e-02Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_52645231 5.79 ENST00000448484.1
breast carcinoma amplified sequence 1
chr12_-_45270077 4.97 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr4_-_109090106 4.86 ENST00000379951.2
lymphoid enhancer-binding factor 1
chr4_-_109089573 4.65 ENST00000265165.1
lymphoid enhancer-binding factor 1
chr12_-_45269769 4.53 ENST00000548826.1
NEL-like 2 (chicken)
chr12_-_45270151 4.51 ENST00000429094.2
NEL-like 2 (chicken)
chr8_+_24151553 4.37 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr11_+_36317830 4.25 ENST00000530639.1
proline rich 5 like
chr14_-_106725723 4.08 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr5_-_146435572 3.51 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr5_-_146435694 3.44 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr14_+_22748980 3.41 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr5_-_146435501 3.34 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr14_-_91884115 3.30 ENST00000389857.6
coiled-coil domain containing 88C
chr14_-_106866934 3.25 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr14_-_106845789 3.25 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_106926724 3.23 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr8_+_24151620 3.12 ENST00000437154.2
ADAM metallopeptidase domain 28
chr3_+_181429704 3.05 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr8_+_61822605 2.99 ENST00000526936.1
AC022182.1
chr11_+_128563652 2.85 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr14_-_106518922 2.82 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr1_-_32801825 2.62 ENST00000329421.7
MARCKS-like 1
chr12_-_62586543 2.62 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr11_-_85430356 2.58 ENST00000526999.1
synaptotagmin-like 2
chr3_+_39509070 2.47 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
myelin-associated oligodendrocyte basic protein
chr14_-_91884150 2.46 ENST00000553403.1
coiled-coil domain containing 88C
chr3_+_39509163 2.41 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
myelin-associated oligodendrocyte basic protein
chr2_-_208031542 2.36 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr5_-_114515734 2.34 ENST00000514154.1
ENST00000282369.3
tripartite motif containing 36
chr5_+_147258266 2.26 ENST00000296694.4
secretoglobin, family 3A, member 2
chr2_-_158182322 2.19 ENST00000420719.2
ENST00000409216.1
ermin, ERM-like protein
chr2_-_166702601 2.11 ENST00000428888.1
AC009495.4
chr2_-_158182410 2.07 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr11_-_85430204 2.07 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chr17_+_30813576 2.02 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_-_204463829 2.02 ENST00000429009.1
ENST00000415899.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_-_26233423 2.01 ENST00000357865.2
stathmin 1
chr11_-_85430163 1.98 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr17_+_72667239 1.97 ENST00000402449.4
RAB37, member RAS oncogene family
chrX_+_12993202 1.96 ENST00000451311.2
ENST00000380636.1
thymosin beta 4, X-linked
chr11_-_94965667 1.92 ENST00000542176.1
ENST00000278499.2
sestrin 3
chr7_-_121944491 1.91 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr11_-_85430088 1.91 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr3_+_111260980 1.87 ENST00000438817.2
CD96 molecule
chr22_-_42336209 1.84 ENST00000472374.2
centromere protein M
chr5_-_157002749 1.84 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM metallopeptidase domain 19
chr1_-_204436344 1.81 ENST00000367184.2
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr16_+_33605231 1.80 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr6_-_24877490 1.75 ENST00000540914.1
ENST00000378023.4
family with sequence similarity 65, member B
chr2_+_27070964 1.74 ENST00000288699.6
dihydropyrimidinase-like 5
chr5_-_157002775 1.74 ENST00000257527.4
ADAM metallopeptidase domain 19
chr6_+_13272904 1.72 ENST00000379335.3
ENST00000379329.1
phosphatase and actin regulator 1
chr12_-_11548496 1.69 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr2_-_9143786 1.69 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr6_-_49712072 1.65 ENST00000423399.2
cysteine-rich secretory protein 3
chr14_-_106791536 1.64 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr2_-_2334888 1.62 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr2_-_135805008 1.60 ENST00000414343.1
mitogen-activated protein kinase kinase kinase 19
chr6_-_133055815 1.57 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr12_+_11081828 1.56 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr1_-_26232951 1.55 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr2_+_27071045 1.54 ENST00000401478.1
dihydropyrimidinase-like 5
chr12_-_50294033 1.53 ENST00000552669.1
Fas apoptotic inhibitory molecule 2
chr1_-_26232522 1.52 ENST00000399728.1
stathmin 1
chr20_-_17511962 1.51 ENST00000377873.3
beaded filament structural protein 1, filensin
chr13_+_51913819 1.46 ENST00000419898.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr7_+_87563557 1.44 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM metallopeptidase domain 22
chr9_-_130712995 1.43 ENST00000373084.4
family with sequence similarity 102, member A
chr7_+_87563458 1.43 ENST00000398204.4
ADAM metallopeptidase domain 22
chr9_+_139874683 1.42 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chrX_+_84499038 1.42 ENST00000373165.3
zinc finger protein 711
chr12_-_11036844 1.42 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr6_-_49712091 1.39 ENST00000371159.4
cysteine-rich secretory protein 3
chrX_+_84498989 1.38 ENST00000395402.1
zinc finger protein 711
chr1_+_240255166 1.37 ENST00000319653.9
formin 2
chr2_-_158182105 1.37 ENST00000409925.1
ermin, ERM-like protein
chr5_-_169725231 1.35 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_-_127840021 1.35 ENST00000465909.2
SOGA family member 3
chr5_+_49962772 1.34 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr6_+_13925098 1.33 ENST00000488300.1
ENST00000544682.1
ENST00000420478.2
ring finger protein 182
chr15_-_52043722 1.33 ENST00000454181.2
LysM, putative peptidoglycan-binding, domain containing 2
chr11_-_123756334 1.33 ENST00000528595.1
ENST00000375026.2
transmembrane protein 225
chr15_+_52043813 1.32 ENST00000435126.2
tropomodulin 2 (neuronal)
chrX_+_84499081 1.32 ENST00000276123.3
zinc finger protein 711
chr17_+_64961026 1.31 ENST00000262138.3
calcium channel, voltage-dependent, gamma subunit 4
chr22_+_43808014 1.30 ENST00000334209.5
ENST00000443721.1
ENST00000414469.2
ENST00000439548.1
metallophosphoesterase domain containing 1
chr7_-_142232071 1.30 ENST00000390364.3
T cell receptor beta variable 10-1(gene/pseudogene)
chr19_+_35783028 1.29 ENST00000600291.1
ENST00000392213.3
myelin associated glycoprotein
chr15_+_52043758 1.28 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr12_-_10151773 1.27 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr15_+_101402041 1.27 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
chrX_+_107288280 1.26 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr6_+_132455118 1.26 ENST00000458028.1
long intergenic non-protein coding RNA 1013
chr13_-_95131923 1.25 ENST00000377028.5
ENST00000446125.1
dopachrome tautomerase
chr7_+_139528952 1.24 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr5_+_139175380 1.24 ENST00000274710.3
pleckstrin and Sec7 domain containing 2
chr10_-_25241499 1.24 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
phosphoribosyl transferase domain containing 1
chr12_-_11508520 1.23 ENST00000545626.1
ENST00000500254.2
proline-rich protein BstNI subfamily 1
chr5_-_180018540 1.23 ENST00000292641.3
secretoglobin, family 3A, member 1
chr22_+_37959647 1.22 ENST00000415670.1
CDC42 effector protein (Rho GTPase binding) 1
chrX_+_12993336 1.20 ENST00000380635.1
thymosin beta 4, X-linked
chr10_+_121578211 1.19 ENST00000369080.3
inositol polyphosphate-5-phosphatase F
chr6_-_127840336 1.19 ENST00000525778.1
SOGA family member 3
chr2_-_157198860 1.19 ENST00000409572.1
nuclear receptor subfamily 4, group A, member 2
chr4_-_143227088 1.19 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr17_-_42441204 1.18 ENST00000293443.7
family with sequence similarity 171, member A2
chr12_-_11463353 1.18 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
proline-rich protein BstNI subfamily 4
chr19_-_51891209 1.15 ENST00000221973.3
ENST00000596399.1
lens intrinsic membrane protein 2, 19kDa
chr14_+_23011142 1.15 ENST00000390533.1
T cell receptor alpha joining 4
chr10_-_99030395 1.13 ENST00000355366.5
ENST00000371027.1
Rho GTPase activating protein 19
chr20_-_35492048 1.13 ENST00000237536.4
suppressor of glucose, autophagy associated 1
chr4_-_143226979 1.11 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr3_+_133118839 1.11 ENST00000302334.2
beaded filament structural protein 2, phakinin
chr20_+_48884002 1.11 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr15_+_81293254 1.11 ENST00000267984.2
mesoderm development candidate 1
chr19_+_35783047 1.11 ENST00000595791.1
ENST00000597035.1
ENST00000537831.2
myelin associated glycoprotein
chr12_-_5352315 1.11 ENST00000536518.1
RP11-319E16.1
chr3_-_123339343 1.11 ENST00000578202.1
myosin light chain kinase
chr12_-_49582978 1.10 ENST00000301071.7
tubulin, alpha 1a
chr6_-_109777128 1.09 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr2_-_37899323 1.08 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr19_+_35783037 1.07 ENST00000361922.4
myelin associated glycoprotein
chr6_-_109776901 1.07 ENST00000431946.1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr3_-_149510553 1.07 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr14_+_100070869 1.06 ENST00000502101.2
RP11-543C4.1
chr6_+_114178512 1.04 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr11_+_63974135 1.04 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
fermitin family member 3
chr1_-_6479963 1.03 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
hes family bHLH transcription factor 2
chr20_+_20348740 1.03 ENST00000310227.1
insulinoma-associated 1
chr6_+_97372596 1.03 ENST00000369261.4
kelch-like family member 32
chr5_-_39424961 1.02 ENST00000503513.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr4_-_87028478 1.01 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr12_+_93096619 1.00 ENST00000397833.3
chromosome 12 open reading frame 74
chr11_+_128563948 0.99 ENST00000534087.2
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_46402583 0.99 ENST00000359803.3
midkine (neurite growth-promoting factor 2)
chr1_+_1361494 0.99 ENST00000378821.3
transmembrane protein 88B
chr5_+_140213815 0.99 ENST00000525929.1
ENST00000378125.3
protocadherin alpha 7
chr1_-_201476274 0.97 ENST00000340006.2
cysteine and glycine-rich protein 1
chr6_-_64029879 0.97 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
lengsin, lens protein with glutamine synthetase domain
chrX_+_65384052 0.97 ENST00000336279.5
ENST00000458621.1
hephaestin
chr1_-_201476220 0.96 ENST00000526723.1
ENST00000524951.1
cysteine and glycine-rich protein 1
chr12_-_49581152 0.95 ENST00000550811.1
tubulin, alpha 1a
chr14_+_103589789 0.95 ENST00000558056.1
ENST00000560869.1
tumor necrosis factor, alpha-induced protein 2
chr9_+_139221880 0.95 ENST00000392945.3
ENST00000440944.1
G-protein signaling modulator 1
chr12_-_99288536 0.95 ENST00000549797.1
ENST00000333732.7
ENST00000341752.7
ankyrin repeat and sterile alpha motif domain containing 1B
chrX_-_153599578 0.94 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr3_-_69402828 0.93 ENST00000460709.1
FERM domain containing 4B
chr17_-_9940058 0.92 ENST00000585266.1
growth arrest-specific 7
chr16_+_89989687 0.92 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr2_-_114647327 0.91 ENST00000602760.1
RP11-141B14.1
chr17_+_75283973 0.91 ENST00000431235.2
ENST00000449803.2
septin 9
chr3_-_123339418 0.90 ENST00000583087.1
myosin light chain kinase
chr4_+_2819883 0.90 ENST00000511747.1
ENST00000503393.2
SH3-domain binding protein 2
chr12_+_25205666 0.89 ENST00000547044.1
lymphoid-restricted membrane protein
chr3_-_181160240 0.87 ENST00000460993.1
RP11-275H4.1
chr13_-_41593425 0.87 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr17_-_9939935 0.87 ENST00000580043.1
growth arrest-specific 7
chr12_+_15475462 0.86 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr1_+_228337553 0.86 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr1_+_212797789 0.86 ENST00000294829.3
family with sequence similarity 71, member A
chr11_+_196738 0.85 ENST00000325113.4
ENST00000342593.5
outer dense fiber of sperm tails 3
chr2_-_70475586 0.85 ENST00000416149.2
TIA1 cytotoxic granule-associated RNA binding protein
chr16_-_22385901 0.84 ENST00000268383.2
cerebellar degeneration-related protein 2, 62kDa
chr2_-_85641162 0.84 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
capping protein (actin filament), gelsolin-like
chr14_-_70038032 0.84 ENST00000543986.1
coiled-coil domain containing 177
chr5_+_55033845 0.83 ENST00000353507.5
ENST00000514278.2
ENST00000505374.1
ENST00000506511.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr5_-_39425068 0.82 ENST00000515700.1
ENST00000339788.6
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr15_+_74610894 0.82 ENST00000558821.1
ENST00000268082.4
coiled-coil domain containing 33
chr6_-_49712123 0.82 ENST00000263045.4
cysteine-rich secretory protein 3
chr1_+_150229554 0.81 ENST00000369111.4
carbonic anhydrase XIV
chr7_+_99006232 0.81 ENST00000403633.2
BUD31 homolog (S. cerevisiae)
chr15_-_80695917 0.81 ENST00000559008.1
Uncharacterized protein
chr17_-_76713100 0.80 ENST00000585509.1
cytohesin 1
chr7_-_71868354 0.80 ENST00000412588.1
calneuron 1
chr19_-_10047219 0.80 ENST00000264833.4
olfactomedin 2
chr12_+_93096759 0.80 ENST00000544406.2
chromosome 12 open reading frame 74
chr15_-_73076030 0.80 ENST00000311669.8
ADP-dependent glucokinase
chr5_+_79615790 0.79 ENST00000296739.4
spermatogenic leucine zipper 1
chrX_+_65384182 0.79 ENST00000441993.2
ENST00000419594.1
hephaestin
chr12_-_49582593 0.78 ENST00000295766.5
tubulin, alpha 1a
chr4_-_103266355 0.78 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chr21_-_40720995 0.77 ENST00000380749.5
high mobility group nucleosome binding domain 1
chrX_+_107288239 0.77 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr11_-_125365435 0.77 ENST00000524435.1
fasciculation and elongation protein zeta 1 (zygin I)
chr22_-_38480100 0.76 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr14_+_22982921 0.76 ENST00000390508.1
T cell receptor alpha joining 29
chr10_-_98118724 0.75 ENST00000393870.2
oligodendrocytic myelin paranodal and inner loop protein
chr12_-_48213568 0.75 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
histone deacetylase 7
chr4_-_103266219 0.75 ENST00000394833.2
solute carrier family 39 (zinc transporter), member 8
chr4_+_26322987 0.74 ENST00000505958.1
recombination signal binding protein for immunoglobulin kappa J region
chr16_+_3704822 0.74 ENST00000414110.2
deoxyribonuclease I
chr12_+_25205628 0.74 ENST00000554942.1
lymphoid-restricted membrane protein
chr7_-_107968999 0.73 ENST00000456431.1
neuronal cell adhesion molecule
chr11_+_125365110 0.73 ENST00000527818.1
AP000708.1
chr1_+_14075865 0.71 ENST00000413440.1
PR domain containing 2, with ZNF domain
chr8_+_27631903 0.71 ENST00000305188.8
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_+_12859080 0.70 ENST00000583608.1
Rho GTPase activating protein 44
chr8_-_20161466 0.70 ENST00000381569.1
leucine zipper, putative tumor suppressor 1
chr2_-_70475701 0.70 ENST00000282574.4
TIA1 cytotoxic granule-associated RNA binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.8 14.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.7 2.0 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.6 1.9 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.6 8.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.5 2.2 GO:0019417 sulfur oxidation(GO:0019417)
0.5 1.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.4 2.9 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4 1.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.4 3.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.4 2.3 GO:0030421 defecation(GO:0030421)
0.4 1.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4 10.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.3 1.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.3 6.2 GO:0038203 TORC2 signaling(GO:0038203)
0.3 1.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 0.9 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 4.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.3 0.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 3.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.3 1.0 GO:0003358 noradrenergic neuron development(GO:0003358)
0.2 2.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.4 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 2.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.6 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.2 1.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.6 GO:0070307 lens fiber cell development(GO:0070307)
0.2 1.0 GO:0010157 response to chlorate(GO:0010157)
0.2 15.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 2.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 1.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.2 2.6 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.1 0.8 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 2.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.0 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.5 GO:0021681 cerebellar granular layer development(GO:0021681)
0.1 1.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 2.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 3.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.7 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.2 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.7 GO:1905066 regulation of Wnt signaling pathway involved in heart development(GO:0003307) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.3 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 5.8 GO:0031648 protein destabilization(GO:0031648)
0.1 2.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0031175 neuron projection development(GO:0031175)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.2 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 1.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 6.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 2.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 2.9 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.8 GO:0006825 copper ion transport(GO:0006825)
0.1 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.4 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 3.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 1.3 GO:0030220 platelet formation(GO:0030220)
0.1 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 1.0 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.7 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 1.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 1.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.2 GO:0035407 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767) histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 4.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.6 GO:0008037 cell recognition(GO:0008037)
0.0 1.1 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.8 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.7 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 1.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 2.6 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0000075 cell cycle checkpoint(GO:0000075)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.4 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 3.9 GO:0009566 fertilization(GO:0009566)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.7 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:0006308 DNA catabolic process(GO:0006308)
0.0 1.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.8 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.7 9.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.5 2.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.4 5.8 GO:0033269 internode region of axon(GO:0033269)
0.3 15.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 2.2 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.4 GO:0036398 TCR signalosome(GO:0036398)
0.3 1.0 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.9 GO:0031523 Myb complex(GO:0031523)
0.2 6.2 GO:0031932 TORC2 complex(GO:0031932)
0.2 0.6 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.2 9.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 1.0 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.8 GO:0071547 piP-body(GO:0071547)
0.1 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.0 1.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.8 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.8 GO:0090543 Flemming body(GO:0090543)
0.0 3.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.7 GO:0097433 dense body(GO:0097433)
0.0 1.1 GO:0005922 connexon complex(GO:0005922)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 4.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 3.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 2.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 9.4 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.2 GO:0043195 terminal bouton(GO:0043195)
0.0 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 2.9 GO:0072562 blood microparticle(GO:0072562)
0.0 3.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.5 9.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.4 1.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4 2.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.4 1.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 3.8 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 1.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.3 8.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 1.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.3 5.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 16.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.2 3.5 GO:0033691 sialic acid binding(GO:0033691)
0.2 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 0.5 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 1.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0005119 smoothened binding(GO:0005119)
0.1 1.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 5.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 1.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 3.1 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.6 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.9 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 2.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 12.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 10.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.2 GO:0071949 FAD binding(GO:0071949)
0.1 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 2.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0000150 recombinase activity(GO:0000150)
0.0 2.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 2.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 4.5 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 8.9 GO:0015631 tubulin binding(GO:0015631)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 5.1 GO:0003924 GTPase activity(GO:0003924)
0.0 1.0 GO:0033613 activating transcription factor binding(GO:0033613)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.2 PID ATR PATHWAY ATR signaling pathway
0.1 2.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 9.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 9.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 4.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 3.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 3.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 3.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway