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Illumina Body Map 2, young vs old

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Results for SOX9

Z-value: 0.30

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Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
SOX9
ENSG00000125398.5 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg19_v2_chr17_+_70117153_701171740.373.9e-02Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_119530428 2.56 ENST00000369429.3
TBX15
T-box 15
chr4_-_186732048 2.37 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr8_+_144295067 2.32 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr6_-_139613269 2.25 ENST00000358430.3
TXLNB
taxilin beta
chr3_-_46904946 2.21 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr8_+_19759228 2.16 ENST00000520959.1
LPL
lipoprotein lipase
chr3_-_46904918 2.14 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr12_-_6233828 2.03 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr19_-_17375527 1.89 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr8_-_82395461 1.88 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr12_-_8815215 1.88 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chrX_-_45060135 1.83 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr13_+_110958124 1.75 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr14_-_38725573 1.73 ENST00000342213.2
CLEC14A
C-type lectin domain family 14, member A
chr10_-_97321112 1.60 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1
sorbin and SH3 domain containing 1
chr11_+_131781290 1.59 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr10_-_97321165 1.58 ENST00000306402.6
SORBS1
sorbin and SH3 domain containing 1
chr12_-_8815299 1.58 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr17_-_39743139 1.55 ENST00000167586.6
KRT14
keratin 14
chr1_+_156589051 1.53 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr5_+_140593509 1.51 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr18_+_7946839 1.51 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr18_+_7946941 1.49 ENST00000444013.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr3_-_112329110 1.48 ENST00000479368.1
CCDC80
coiled-coil domain containing 80
chr16_+_82660560 1.48 ENST00000268613.10
ENST00000565636.1
ENST00000431540.3
ENST00000428848.3
CDH13
cadherin 13
chr10_+_24497704 1.39 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr5_+_148521454 1.38 ENST00000508983.1
ABLIM3
actin binding LIM protein family, member 3
chr12_-_18243119 1.38 ENST00000538724.1
ENST00000229002.2
RERGL
RERG/RAS-like
chr6_-_75915757 1.37 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr4_+_41614909 1.35 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr12_+_53443680 1.32 ENST00000314250.6
ENST00000451358.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_149051194 1.30 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr17_+_8213590 1.27 ENST00000361926.3
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr10_+_24498060 1.26 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr5_-_146833485 1.25 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr12_+_53443963 1.24 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_185826855 1.23 ENST00000306376.5
ETV5
ets variant 5
chr17_+_1666108 1.23 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_100565249 1.22 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr10_+_24528108 1.19 ENST00000438429.1
KIAA1217
KIAA1217
chr10_+_102106829 1.16 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr12_-_8815477 1.16 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr7_-_131241361 1.14 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr4_+_41614720 1.14 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr5_-_146833803 1.13 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr3_-_149051444 1.13 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr19_-_17375541 1.12 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr1_-_79472365 1.12 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr6_+_53976235 1.09 ENST00000502396.1
ENST00000358276.5
MLIP
muscular LMNA-interacting protein
chr1_+_185703513 1.08 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr9_-_124989804 1.08 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr22_-_19512893 1.06 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr10_+_6244829 1.05 ENST00000317350.4
ENST00000379785.1
ENST00000379782.3
ENST00000360521.2
ENST00000379775.4
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_-_38080077 1.04 ENST00000378533.3
ENST00000544439.1
ENST00000432886.2
ENST00000538295.1
SRPX
sushi-repeat containing protein, X-linked
chr17_-_73505961 1.04 ENST00000433559.2
CASKIN2
CASK interacting protein 2
chr5_+_140602904 1.04 ENST00000515856.2
ENST00000239449.4
PCDHB14
protocadherin beta 14
chr6_+_53976211 1.02 ENST00000503951.1
MLIP
muscular LMNA-interacting protein
chr9_+_27109392 1.02 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr2_-_151344172 1.02 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr9_+_27109440 1.02 ENST00000519080.1
TEK
TEK tyrosine kinase, endothelial
chr6_+_148663729 1.01 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr12_-_71003568 1.00 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_+_124461603 1.00 ENST00000373782.3
DAB2IP
DAB2 interacting protein
chr3_-_65583561 1.00 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr5_+_15500280 0.99 ENST00000504595.1
FBXL7
F-box and leucine-rich repeat protein 7
chr2_-_158182410 0.99 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr9_+_27109133 0.96 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr17_+_8213539 0.96 ENST00000583529.1
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chrX_+_114874727 0.96 ENST00000543070.1
PLS3
plastin 3
chr9_+_2622085 0.96 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr12_-_111358372 0.94 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr16_+_82660635 0.94 ENST00000567445.1
ENST00000446376.2
CDH13
cadherin 13
chr13_+_113656092 0.93 ENST00000397024.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_27339317 0.93 ENST00000289166.5
FAM46B
family with sequence similarity 46, member B
chr15_+_71184931 0.92 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr16_+_66400533 0.92 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr19_-_8408139 0.92 ENST00000330915.3
ENST00000593649.1
ENST00000595639.1
KANK3
KN motif and ankyrin repeat domains 3
chr8_-_38326139 0.92 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
FGFR1
fibroblast growth factor receptor 1
chr3_+_85008089 0.90 ENST00000383699.3
CADM2
cell adhesion molecule 2
chr6_-_46293378 0.89 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr5_-_158526693 0.89 ENST00000380654.4
EBF1
early B-cell factor 1
chr5_-_146833222 0.88 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr4_-_182186182 0.88 ENST00000512547.1
RP11-665C14.2
RP11-665C14.2
chr17_-_56605341 0.88 ENST00000583114.1
SEPT4
septin 4
chr11_+_60691924 0.88 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A
transmembrane protein 132A
chr7_+_107110488 0.86 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr1_+_43766642 0.86 ENST00000372476.3
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr5_-_141338627 0.85 ENST00000231484.3
PCDH12
protocadherin 12
chr20_+_61147651 0.85 ENST00000370527.3
ENST00000370524.2
C20orf166
chromosome 20 open reading frame 166
chr6_+_53976285 0.85 ENST00000514433.1
MLIP
muscular LMNA-interacting protein
chr7_-_107968921 0.84 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr10_-_105845674 0.83 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr12_-_88974236 0.82 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr5_-_83680192 0.82 ENST00000380138.3
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr8_-_38326119 0.81 ENST00000356207.5
ENST00000326324.6
FGFR1
fibroblast growth factor receptor 1
chr5_-_158526756 0.81 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr1_+_43766668 0.80 ENST00000441333.2
ENST00000538015.1
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr17_-_14683517 0.80 ENST00000379640.1
AC005863.1
AC005863.1
chr7_-_27219849 0.80 ENST00000396344.4
HOXA10
homeobox A10
chr4_-_186732241 0.80 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_55277436 0.78 ENST00000354474.6
RTN4
reticulon 4
chr5_-_83680603 0.78 ENST00000296591.5
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr2_-_1748214 0.78 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN
peroxidasin homolog (Drosophila)
chr4_-_186732892 0.78 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
SORBS2
sorbin and SH3 domain containing 2
chr5_+_140557371 0.77 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr1_-_217311090 0.77 ENST00000493603.1
ENST00000366940.2
ESRRG
estrogen-related receptor gamma
chr3_+_89156674 0.77 ENST00000336596.2
EPHA3
EPH receptor A3
chr1_+_156589198 0.77 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr14_+_63671105 0.75 ENST00000316754.3
RHOJ
ras homolog family member J
chr7_-_11871815 0.74 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr9_+_112403059 0.73 ENST00000374531.2
PALM2
paralemmin 2
chr2_-_55277692 0.72 ENST00000394611.2
RTN4
reticulon 4
chr9_-_140196703 0.71 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr17_+_16945820 0.71 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr4_-_110723335 0.70 ENST00000394634.2
CFI
complement factor I
chr16_+_2083265 0.69 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr2_-_55277654 0.69 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr2_-_55277512 0.69 ENST00000402434.2
RTN4
reticulon 4
chr2_-_158182322 0.69 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr1_-_85930246 0.69 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_+_45971246 0.69 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr12_+_95611536 0.69 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr4_-_110723194 0.68 ENST00000394635.3
CFI
complement factor I
chr2_+_30569506 0.68 ENST00000421976.2
AC109642.1
AC109642.1
chr5_+_140739537 0.67 ENST00000522605.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr12_-_24715478 0.67 ENST00000456299.2
ENST00000540811.1
RP11-444D3.1
RP11-444D3.1
chr3_-_185826718 0.67 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr5_+_172068232 0.66 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr17_+_36584662 0.66 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr11_-_65640071 0.66 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr2_-_175869936 0.65 ENST00000409900.3
CHN1
chimerin 1
chr8_+_70378852 0.65 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr5_+_140729649 0.65 ENST00000523390.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr10_-_61122934 0.65 ENST00000512919.1
FAM13C
family with sequence similarity 13, member C
chr10_+_73724123 0.65 ENST00000373115.4
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr11_+_77532233 0.65 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr7_-_22233442 0.64 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_220309379 0.64 ENST00000451076.1
SPEG
SPEG complex locus
chr8_-_93115445 0.64 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_140797296 0.63 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr9_+_112852477 0.63 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr14_-_95236551 0.63 ENST00000238558.3
GSC
goosecoid homeobox
chr1_+_164528866 0.63 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr6_+_13272904 0.63 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr19_+_36359341 0.62 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr8_-_42358742 0.62 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr5_-_146889619 0.62 ENST00000343218.5
DPYSL3
dihydropyrimidinase-like 3
chr22_+_38864041 0.62 ENST00000216014.4
ENST00000409006.3
KDELR3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr11_+_77532155 0.62 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC
adipogenesis associated, Mth938 domain containing
chr1_-_182360498 0.61 ENST00000417584.2
GLUL
glutamate-ammonia ligase
chr1_+_209602156 0.61 ENST00000429156.1
ENST00000366437.3
ENST00000603283.1
ENST00000431096.1
MIR205HG
MIR205 host gene (non-protein coding)
chr9_-_85882145 0.61 ENST00000328788.1
FRMD3
FERM domain containing 3
chr21_+_17442799 0.61 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr7_+_116312411 0.60 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chrM_+_4431 0.60 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr11_-_76155618 0.60 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr1_+_93913713 0.60 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr7_-_107643567 0.60 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr3_+_69985734 0.60 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr18_-_21891460 0.60 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chrX_+_103028638 0.60 ENST00000434483.1
PLP1
proteolipid protein 1
chr4_-_110723134 0.60 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr15_+_101402041 0.59 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr4_-_87028478 0.59 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr18_-_53177984 0.59 ENST00000543082.1
TCF4
transcription factor 4
chr7_-_112635675 0.58 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr16_+_15528332 0.58 ENST00000566490.1
C16orf45
chromosome 16 open reading frame 45
chr8_-_38325219 0.58 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
FGFR1
fibroblast growth factor receptor 1
chr14_-_21516590 0.57 ENST00000555026.1
NDRG2
NDRG family member 2
chrX_-_17878827 0.57 ENST00000360011.1
RAI2
retinoic acid induced 2
chr20_-_1317555 0.56 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr11_+_68080077 0.56 ENST00000294304.7
LRP5
low density lipoprotein receptor-related protein 5
chr11_-_76155700 0.56 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr2_-_175629164 0.56 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr3_+_69985792 0.55 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr6_-_127840048 0.55 ENST00000467753.1
SOGA3
SOGA family member 3
chr19_+_48972459 0.55 ENST00000427476.1
CYTH2
cytohesin 2
chr1_-_205904950 0.55 ENST00000340781.4
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr3_-_48470838 0.54 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr11_-_44971702 0.54 ENST00000533940.1
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr10_-_105845536 0.54 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1
chr7_-_107643674 0.54 ENST00000222399.6
LAMB1
laminin, beta 1
chr2_+_223536428 0.53 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr16_-_46782221 0.53 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr17_-_10372875 0.52 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr15_-_37392703 0.52 ENST00000382766.2
ENST00000444725.1
MEIS2
Meis homeobox 2
chr12_-_24715376 0.52 ENST00000446891.2
ENST00000429944.2
RP11-444D3.1
RP11-444D3.1
chr2_+_168725458 0.52 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_+_134464376 0.52 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr12_+_130646999 0.51 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr11_+_110001723 0.51 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr1_+_164529004 0.51 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr5_-_16936340 0.51 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr5_-_141338377 0.50 ENST00000510041.1
PCDH12
protocadherin 12
chr21_+_41239243 0.50 ENST00000328619.5
PCP4
Purkinje cell protein 4
chr13_+_98795505 0.50 ENST00000319562.6
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr10_+_70748487 0.50 ENST00000361983.4
KIAA1279
KIAA1279
chr7_+_128379449 0.50 ENST00000479257.1
CALU
calumenin
chr12_+_95611569 0.50 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr7_+_94537542 0.50 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 1.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 2.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.4 3.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 2.3 GO:0071503 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.3 0.6 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 4.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 1.2 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.3 3.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 0.8 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.3 1.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.2 0.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.2 1.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 2.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 1.9 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 0.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.9 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.2 1.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 0.5 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 1.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.5 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.6 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.6 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.7 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 4.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.0 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 4.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 3.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 4.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 5.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.3 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 3.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 0.4 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 1.8 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 2.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 0.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 2.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 1.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.7 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.7 GO:0098722 asymmetric stem cell division(GO:0098722)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 1.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 2.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.5 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.3 GO:1902952 regulation of postsynaptic density protein 95 clustering(GO:1902897) positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0032900 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 6.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.7 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.7 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 1.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 1.7 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 1.2 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 4.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.1 GO:1903935 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 4.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.7 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.9 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.3 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.9 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.0 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 2.0 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 1.0 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005595 collagen type XII trimer(GO:0005595)
0.5 3.2 GO:0005899 insulin receptor complex(GO:0005899)
0.4 2.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 1.1 GO:0043257 laminin-8 complex(GO:0043257)
0.3 1.0 GO:1990032 parallel fiber(GO:1990032)
0.2 1.8 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 4.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.5 GO:0036457 keratohyalin granule(GO:0036457)
0.2 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.4 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 2.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 4.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 2.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0044326 dendritic spine neck(GO:0044326)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 4.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 3.7 GO:0031941 filamentous actin(GO:0031941)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0016011 dystroglycan complex(GO:0016011)
0.1 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.0 GO:0043194 axon initial segment(GO:0043194)
0.0 0.9 GO:0097227 sperm annulus(GO:0097227)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.8 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.5 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.6 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 9.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 4.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 1.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.1 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.5 2.2 GO:0017129 triglyceride binding(GO:0017129)
0.5 2.4 GO:0055100 adiponectin binding(GO:0055100)
0.3 2.3 GO:0035473 lipase binding(GO:0035473)
0.3 4.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 1.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.2 1.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 1.5 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 2.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.6 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 0.8 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 0.6 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 4.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0004803 transposase activity(GO:0004803)
0.1 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 3.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 10.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.5 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 2.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.2 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 5.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 3.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 1.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.0 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0031014 troponin T binding(GO:0031014)
0.0 1.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 3.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 1.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.0 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 4.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 4.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.3 PID INSULIN PATHWAY Insulin Pathway
0.0 4.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 3.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 4.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA