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Illumina Body Map 2, young vs old

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Results for SP100

Z-value: 0.55

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Transcription factors associated with SP100

Gene Symbol Gene ID Gene Info
SP100
ENSG00000067066.12 SP100 nuclear antigen

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SP100hg19_v2_chr2_+_231280908_2312809450.441.2e-02Click!

Activity profile of SP100 motif

Sorted Z-values of SP100 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_45909585 1.39 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr2_-_89399845 1.28 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr4_-_54518619 1.26 ENST00000507168.1
ENST00000510143.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr8_+_24241789 1.16 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr5_+_177540444 1.15 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr2_+_90192768 1.11 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr3_-_150996239 1.10 ENST00000309170.3
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr8_+_24241969 1.10 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr10_-_4285835 1.05 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr5_+_118604385 1.02 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr14_-_106586656 1.01 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr13_-_97646604 0.90 ENST00000298440.1
ENST00000543457.1
ENST00000541038.1
OXGR1
oxoglutarate (alpha-ketoglutarate) receptor 1
chr16_+_85936295 0.90 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr7_-_80551671 0.90 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_4285923 0.90 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr12_+_13044787 0.87 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr4_+_156588806 0.84 ENST00000513574.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_+_89975669 0.84 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr5_-_43397184 0.83 ENST00000513525.1
CCL28
chemokine (C-C motif) ligand 28
chr5_+_40841276 0.80 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr11_+_35201826 0.80 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr12_+_97306295 0.80 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr2_+_220495800 0.79 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr19_-_44172396 0.77 ENST00000602141.1
ENST00000593939.1
ENST00000599546.1
PLAUR
plasminogen activator, urokinase receptor
chr4_+_156588249 0.76 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_+_114163945 0.74 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr4_+_156588115 0.74 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr7_-_81635106 0.74 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr2_-_228582709 0.73 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr6_+_31165901 0.73 ENST00000424675.1
HCG27
HLA complex group 27 (non-protein coding)
chr17_+_45286706 0.72 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr4_+_156588350 0.71 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr2_-_89292422 0.70 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr6_+_116601265 0.70 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr4_+_15341442 0.70 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr1_+_62439037 0.69 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr9_+_112887772 0.69 ENST00000259318.7
AKAP2
A kinase (PRKA) anchor protein 2
chr4_+_169418255 0.69 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr6_+_121756809 0.69 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr16_-_69760409 0.68 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NQO1
NAD(P)H dehydrogenase, quinone 1
chr4_-_90757364 0.67 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_140514782 0.67 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr19_+_12175596 0.67 ENST00000441304.2
ZNF844
zinc finger protein 844
chr14_-_106478603 0.67 ENST00000390596.2
IGHV4-4
immunoglobulin heavy variable 4-4
chr5_+_118604439 0.66 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr19_+_44331444 0.65 ENST00000324461.7
ZNF283
zinc finger protein 283
chr5_+_148651469 0.64 ENST00000515000.1
AFAP1L1
actin filament associated protein 1-like 1
chr8_+_104310661 0.64 ENST00000522566.1
FZD6
frizzled family receptor 6
chr1_-_108735440 0.63 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr19_+_44331493 0.62 ENST00000588797.1
ZNF283
zinc finger protein 283
chr6_+_135502408 0.62 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr5_+_148651409 0.61 ENST00000296721.4
AFAP1L1
actin filament associated protein 1-like 1
chr5_+_54455946 0.61 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr1_+_24829384 0.60 ENST00000374395.4
ENST00000436717.2
RCAN3
RCAN family member 3
chr8_-_19459993 0.60 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr16_+_55512742 0.59 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr5_+_40841410 0.59 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr19_+_44331555 0.58 ENST00000590950.1
ZNF283
zinc finger protein 283
chr1_+_90098606 0.58 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr8_+_94767072 0.58 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
TMEM67
transmembrane protein 67
chr1_-_117210290 0.57 ENST00000369483.1
ENST00000369486.3
IGSF3
immunoglobulin superfamily, member 3
chrX_+_70586140 0.57 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr19_+_56989609 0.57 ENST00000601875.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr19_+_58095501 0.56 ENST00000536878.2
ENST00000597850.1
ENST00000597219.1
ENST00000598689.1
ENST00000599456.1
ENST00000307468.4
ZIK1
zinc finger protein interacting with K protein 1
chr4_-_5710257 0.55 ENST00000344938.1
ENST00000344408.5
EVC2
Ellis van Creveld syndrome 2
chr11_-_76381781 0.55 ENST00000260061.5
ENST00000404995.1
LRRC32
leucine rich repeat containing 32
chr2_+_85132749 0.55 ENST00000233143.4
TMSB10
thymosin beta 10
chr6_-_27806117 0.54 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr22_+_32455111 0.54 ENST00000543737.1
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr8_+_69242957 0.53 ENST00000518698.1
ENST00000539993.1
C8orf34
chromosome 8 open reading frame 34
chr11_+_62037622 0.53 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chrX_-_50386648 0.53 ENST00000460112.3
SHROOM4
shroom family member 4
chr16_+_71392616 0.53 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2
calbindin 2
chr6_+_135502501 0.52 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr10_-_28623368 0.52 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr2_+_241544834 0.52 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr6_+_29691056 0.51 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr19_+_12203069 0.51 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr3_+_62304648 0.51 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr11_+_60145948 0.51 ENST00000300184.3
ENST00000358246.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr8_+_104383728 0.50 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr11_+_102980126 0.50 ENST00000375735.2
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr18_-_46475696 0.50 ENST00000591805.1
SMAD7
SMAD family member 7
chr3_+_62304712 0.49 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr4_+_41540160 0.49 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr2_+_201994569 0.49 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr6_+_26204825 0.49 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr13_+_114462193 0.49 ENST00000375353.3
TMEM255B
transmembrane protein 255B
chr10_-_69425399 0.48 ENST00000330298.6
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr11_-_5248294 0.48 ENST00000335295.4
HBB
hemoglobin, beta
chr19_-_44172467 0.48 ENST00000599892.1
PLAUR
plasminogen activator, urokinase receptor
chr6_+_150285135 0.48 ENST00000229708.3
ULBP1
UL16 binding protein 1
chr5_-_157161727 0.48 ENST00000599823.1
AC026407.1
Uncharacterized protein
chr11_-_118550375 0.48 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
TREH
trehalase (brush-border membrane glycoprotein)
chr7_-_120498357 0.47 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr9_-_137809718 0.47 ENST00000371806.3
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr2_+_183943464 0.47 ENST00000354221.4
DUSP19
dual specificity phosphatase 19
chr12_+_56435637 0.47 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr6_+_32709119 0.46 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr4_+_89299994 0.46 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr12_+_12938541 0.46 ENST00000356591.4
APOLD1
apolipoprotein L domain containing 1
chr13_-_30169807 0.46 ENST00000380752.5
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr14_-_106471723 0.46 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr7_-_151330218 0.46 ENST00000476632.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr3_+_8543561 0.45 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr19_-_52391220 0.45 ENST00000419138.1
ZNF577
zinc finger protein 577
chr6_+_29691198 0.45 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_-_18249971 0.44 ENST00000507591.1
DEK
DEK oncogene
chr7_+_98971863 0.44 ENST00000443222.1
ENST00000414376.1
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr3_+_155838337 0.43 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_-_24898731 0.43 ENST00000267406.6
CBLN3
cerebellin 3 precursor
chr1_-_158656488 0.43 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr4_-_57522673 0.43 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOPX
HOP homeobox
chr6_-_41888843 0.43 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr3_-_16524357 0.43 ENST00000432519.1
RFTN1
raftlin, lipid raft linker 1
chr4_+_37245799 0.42 ENST00000309447.5
KIAA1239
KIAA1239
chr2_+_168043793 0.42 ENST00000409273.1
ENST00000409605.1
XIRP2
xin actin-binding repeat containing 2
chr21_-_43346790 0.42 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chr11_+_60145967 0.41 ENST00000534016.1
MS4A7
membrane-spanning 4-domains, subfamily A, member 7
chr15_+_42066888 0.41 ENST00000510535.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr5_+_140593509 0.41 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr2_-_37068530 0.41 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr19_+_41103063 0.41 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr3_+_153202284 0.41 ENST00000446603.2
C3orf79
chromosome 3 open reading frame 79
chr4_+_86396321 0.40 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr11_+_6947720 0.40 ENST00000414517.2
ZNF215
zinc finger protein 215
chr20_+_30309001 0.39 ENST00000597287.1
AL160175.1
AL160175.1
chr1_-_79472365 0.39 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr17_-_3571934 0.39 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr19_+_52901094 0.39 ENST00000391788.2
ENST00000436397.1
ENST00000391787.2
ENST00000360465.3
ENST00000494167.2
ENST00000493272.1
ZNF528
zinc finger protein 528
chr18_+_3247779 0.38 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr19_-_7812446 0.38 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr8_+_59465728 0.38 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP
syndecan binding protein (syntenin)
chr15_+_45021183 0.37 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr3_-_11685345 0.37 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr13_-_36944307 0.37 ENST00000355182.4
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr19_+_48281928 0.37 ENST00000593892.1
SEPW1
selenoprotein W, 1
chr2_+_201994042 0.37 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr10_+_60272814 0.37 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr16_-_57831914 0.37 ENST00000421376.2
KIFC3
kinesin family member C3
chr7_-_7782204 0.37 ENST00000418534.2
AC007161.5
AC007161.5
chr7_+_97361218 0.37 ENST00000319273.5
TAC1
tachykinin, precursor 1
chr1_+_2487800 0.37 ENST00000355716.4
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr1_+_104068312 0.37 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr22_-_37976082 0.36 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr11_-_76381029 0.36 ENST00000407242.2
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr6_+_26199737 0.36 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr15_-_72410350 0.36 ENST00000356056.5
ENST00000424560.1
ENST00000444904.1
MYO9A
myosin IXA
chr7_+_30589829 0.36 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr2_-_183106641 0.36 ENST00000346717.4
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_+_5890802 0.36 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chrX_+_100353153 0.36 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr17_-_8079648 0.35 ENST00000449985.2
ENST00000532998.1
ENST00000437139.2
ENST00000533070.1
ENST00000316425.5
TMEM107
transmembrane protein 107
chr19_-_36822595 0.35 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665
long intergenic non-protein coding RNA 665
chr19_+_38085731 0.35 ENST00000589117.1
ZNF540
zinc finger protein 540
chr19_+_7580103 0.35 ENST00000596712.1
ZNF358
zinc finger protein 358
chr17_-_15587602 0.35 ENST00000416464.2
ENST00000578237.1
ENST00000581200.1
TRIM16
tripartite motif containing 16
chr1_+_2487402 0.35 ENST00000451778.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr22_+_27068704 0.35 ENST00000444388.1
ENST00000450963.1
ENST00000449017.1
CTA-211A9.5
CTA-211A9.5
chr15_-_72410306 0.35 ENST00000566885.1
MYO9A
myosin IXA
chrX_+_15767971 0.34 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr17_-_8079632 0.34 ENST00000431792.2
TMEM107
transmembrane protein 107
chr4_-_57522598 0.34 ENST00000553379.2
HOPX
HOP homeobox
chr12_+_2079939 0.34 ENST00000543114.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr6_-_41888814 0.34 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr1_+_2487631 0.34 ENST00000409119.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr10_-_103815874 0.34 ENST00000370033.4
ENST00000311122.5
C10orf76
chromosome 10 open reading frame 76
chr4_+_169418195 0.34 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr16_+_22518495 0.33 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr12_-_110318130 0.33 ENST00000540772.1
GLTP
glycolipid transfer protein
chr3_+_40498783 0.33 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14
ribosomal protein L14
chr13_+_43597269 0.33 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr17_+_39969183 0.33 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr19_+_38085768 0.32 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr6_-_46424599 0.32 ENST00000405162.1
RCAN2
regulator of calcineurin 2
chr2_+_29353520 0.32 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr13_+_114567131 0.32 ENST00000608651.1
GAS6-AS2
GAS6 antisense RNA 2 (head to head)
chrX_-_10588595 0.31 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr19_+_53836985 0.31 ENST00000601857.1
ENST00000595091.1
ENST00000458035.1
ZNF845
zinc finger protein 845
chr1_+_44115814 0.31 ENST00000372396.3
KDM4A
lysine (K)-specific demethylase 4A
chr2_-_70475730 0.31 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr6_-_33048483 0.31 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr15_-_72410455 0.31 ENST00000569314.1
MYO9A
myosin IXA
chr7_+_117824086 0.31 ENST00000249299.2
ENST00000424702.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr9_-_99775862 0.31 ENST00000602917.1
ENST00000375223.4
HIATL2
hippocampus abundant transcript-like 2
chr21_-_48024986 0.30 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr6_+_32407619 0.30 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr19_-_52391142 0.30 ENST00000446514.1
ENST00000458390.1
ENST00000420592.1
ENST00000451628.2
ENST00000592321.1
ENST00000591320.1
ENST00000412216.1
ENST00000301399.5
ZNF577
zinc finger protein 577
chr14_+_75745477 0.30 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr7_+_117824210 0.30 ENST00000422760.1
ENST00000411938.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr19_-_53400813 0.30 ENST00000595635.1
ENST00000594741.1
ENST00000597111.1
ENST00000593618.1
ENST00000597909.1
ZNF320
zinc finger protein 320
chr21_-_27462351 0.30 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr2_-_47403642 0.30 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr2_+_201987200 0.30 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr18_-_52989217 0.29 ENST00000570287.2
TCF4
transcription factor 4
chr7_+_128095900 0.29 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr19_-_54876414 0.29 ENST00000474878.1
ENST00000348231.4
LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr7_+_870547 0.29 ENST00000457598.1
SUN1
Sad1 and UNC84 domain containing 1
chr3_-_138553779 0.29 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr12_-_10978957 0.29 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10

Network of associatons between targets according to the STRING database.

First level regulatory network of SP100

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.5 1.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.7 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 1.0 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 0.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.7 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 0.5 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.5 GO:0030185 nitric oxide transport(GO:0030185)
0.1 1.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 1.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.6 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 1.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.1 1.0 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.7 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.7 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.4 GO:1905154 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.3 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.2 GO:0061567 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 1.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.3 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.2 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1 0.7 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 1.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.5 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.6 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.6 GO:0015866 ADP transport(GO:0015866)
0.0 0.2 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.7 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 1.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.5 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.5 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.0 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475) mRNA methylation(GO:0080009)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.2 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0042325 regulation of phosphorylation(GO:0042325)
0.0 0.1 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1904925 negative regulation of mitochondrial fusion(GO:0010637) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 3.6 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.0 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0050911 detection of stimulus involved in sensory perception(GO:0050906) detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031417 NatC complex(GO:0031417)
0.1 0.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.4 GO:0036284 tubulobulbar complex(GO:0036284)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.3 GO:0071437 invadopodium(GO:0071437)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 1.8 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.7 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.7 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.2 0.7 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 1.3 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.5 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.7 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.0 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.5 GO:0019862 IgA binding(GO:0019862)
0.1 0.4 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 1.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 1.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 3.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.4 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.5 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.2 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 0.4 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1 0.3 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 0.5 GO:0015265 urea channel activity(GO:0015265)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 2.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 1.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 6.4 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.0 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 2.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters