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Illumina Body Map 2, young vs old
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Results for SRY
Z-value: 0.37
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Transcription factors associated with SRY
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SRY
|
ENSG00000184895.6 | sex determining region Y |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SRY | hg19_v2_chrY_-_2655644_2655740 | -0.14 | 4.4e-01 | Click! |
Activity profile of SRY motif
Sorted Z-values of SRY motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_39509070 | 4.42 |
ENST00000354668.4
ENST00000428261.1 ENST00000420739.1 ENST00000415443.1 ENST00000447324.1 ENST00000383754.3 |
MOBP
|
myelin-associated oligodendrocyte basic protein |
| chr11_+_112832090 | 3.85 |
ENST00000533760.1
|
NCAM1
|
neural cell adhesion molecule 1 |
| chr8_+_67405794 | 3.54 |
ENST00000522977.1
ENST00000480005.1 |
C8orf46
|
chromosome 8 open reading frame 46 |
| chr3_+_39509163 | 3.24 |
ENST00000436143.2
ENST00000441980.2 ENST00000311042.6 |
MOBP
|
myelin-associated oligodendrocyte basic protein |
| chr8_+_67405755 | 3.16 |
ENST00000521495.1
|
C8orf46
|
chromosome 8 open reading frame 46 |
| chr5_-_146435572 | 2.95 |
ENST00000394414.1
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr5_-_146435694 | 2.90 |
ENST00000356826.3
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr2_-_2334888 | 2.84 |
ENST00000428368.2
ENST00000399161.2 |
MYT1L
|
myelin transcription factor 1-like |
| chr5_-_146435501 | 2.69 |
ENST00000336640.6
|
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr10_+_11206925 | 2.49 |
ENST00000354440.2
ENST00000315874.4 ENST00000427450.1 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chrX_+_107288280 | 2.38 |
ENST00000458383.1
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr7_+_28452130 | 2.34 |
ENST00000357727.2
|
CREB5
|
cAMP responsive element binding protein 5 |
| chr9_-_92051391 | 2.18 |
ENST00000420681.2
|
SEMA4D
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| chr5_-_146461027 | 2.07 |
ENST00000394410.2
ENST00000508267.1 ENST00000504198.1 |
PPP2R2B
|
protein phosphatase 2, regulatory subunit B, beta |
| chr11_+_112832133 | 2.07 |
ENST00000524665.1
|
NCAM1
|
neural cell adhesion molecule 1 |
| chr9_-_92051354 | 2.07 |
ENST00000418828.1
|
SEMA4D
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| chr21_-_32931290 | 2.06 |
ENST00000286827.3
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1 |
| chr12_-_62586543 | 2.04 |
ENST00000416284.3
|
FAM19A2
|
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 |
| chr5_-_111091948 | 2.03 |
ENST00000447165.2
|
NREP
|
neuronal regeneration related protein |
| chr11_+_112832202 | 2.03 |
ENST00000534015.1
|
NCAM1
|
neural cell adhesion molecule 1 |
| chr14_-_60097297 | 2.01 |
ENST00000395090.1
|
RTN1
|
reticulon 1 |
| chr11_-_35441524 | 1.98 |
ENST00000395750.1
ENST00000449068.1 |
SLC1A2
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| chr5_-_147162263 | 1.97 |
ENST00000333010.6
ENST00000265272.5 |
JAKMIP2
|
janus kinase and microtubule interacting protein 2 |
| chr11_-_35441597 | 1.91 |
ENST00000395753.1
|
SLC1A2
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| chr11_-_35440796 | 1.88 |
ENST00000278379.3
|
SLC1A2
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| chr12_-_121973974 | 1.68 |
ENST00000538379.1
ENST00000541318.1 ENST00000541511.1 |
KDM2B
|
lysine (K)-specific demethylase 2B |
| chr10_+_11207088 | 1.68 |
ENST00000608830.1
|
CELF2
|
CUGBP, Elav-like family member 2 |
| chr1_-_40367668 | 1.64 |
ENST00000397332.2
ENST00000429311.1 |
MYCL
|
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| chr1_-_193155729 | 1.64 |
ENST00000367434.4
|
B3GALT2
|
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| chr4_-_164534657 | 1.62 |
ENST00000339875.5
|
MARCH1
|
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase |
| chr11_-_46848393 | 1.60 |
ENST00000526496.1
|
CKAP5
|
cytoskeleton associated protein 5 |
| chr1_+_84630352 | 1.60 |
ENST00000450730.1
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr3_-_10332416 | 1.60 |
ENST00000450603.1
ENST00000449554.2 |
GHRL
|
ghrelin/obestatin prepropeptide |
| chr1_+_50574585 | 1.51 |
ENST00000371824.1
ENST00000371823.4 |
ELAVL4
|
ELAV like neuron-specific RNA binding protein 4 |
| chr20_-_52612705 | 1.51 |
ENST00000434986.2
|
BCAS1
|
breast carcinoma amplified sequence 1 |
| chr14_+_22994472 | 1.50 |
ENST00000390519.1
|
TRAJ18
|
T cell receptor alpha joining 18 |
| chr5_+_173930676 | 1.48 |
ENST00000504512.1
|
RP11-267A15.1
|
RP11-267A15.1 |
| chr1_-_40367530 | 1.41 |
ENST00000372816.2
ENST00000372815.1 |
MYCL
|
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| chr17_-_37764128 | 1.41 |
ENST00000302584.4
|
NEUROD2
|
neuronal differentiation 2 |
| chrX_-_19689106 | 1.41 |
ENST00000379716.1
|
SH3KBP1
|
SH3-domain kinase binding protein 1 |
| chr20_-_52645231 | 1.39 |
ENST00000448484.1
|
BCAS1
|
breast carcinoma amplified sequence 1 |
| chr22_+_19710468 | 1.38 |
ENST00000366425.3
|
GP1BB
|
glycoprotein Ib (platelet), beta polypeptide |
| chr1_+_84630645 | 1.38 |
ENST00000394839.2
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr1_+_84630574 | 1.36 |
ENST00000413538.1
ENST00000417530.1 |
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr3_-_71353892 | 1.36 |
ENST00000484350.1
|
FOXP1
|
forkhead box P1 |
| chr1_+_50571949 | 1.35 |
ENST00000357083.4
|
ELAVL4
|
ELAV like neuron-specific RNA binding protein 4 |
| chr1_+_84630053 | 1.35 |
ENST00000394838.2
ENST00000370682.3 ENST00000432111.1 |
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr14_-_89960395 | 1.35 |
ENST00000555034.1
ENST00000553904.1 |
FOXN3
|
forkhead box N3 |
| chrX_+_28605516 | 1.33 |
ENST00000378993.1
|
IL1RAPL1
|
interleukin 1 receptor accessory protein-like 1 |
| chr1_+_84630367 | 1.32 |
ENST00000370680.1
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr2_+_181988560 | 1.32 |
ENST00000424170.1
ENST00000435411.1 |
AC104820.2
|
AC104820.2 |
| chr10_+_99079008 | 1.26 |
ENST00000371021.3
|
FRAT1
|
frequently rearranged in advanced T-cell lymphomas |
| chr5_-_88120151 | 1.24 |
ENST00000506716.1
|
MEF2C
|
myocyte enhancer factor 2C |
| chr13_-_114843416 | 1.22 |
ENST00000389544.4
|
RASA3
|
RAS p21 protein activator 3 |
| chrX_+_107288197 | 1.19 |
ENST00000415430.3
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr13_-_46716969 | 1.19 |
ENST00000435666.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr8_-_124553437 | 1.18 |
ENST00000517956.1
ENST00000443022.2 |
FBXO32
|
F-box protein 32 |
| chr13_-_99910620 | 1.16 |
ENST00000416594.1
|
GPR18
|
G protein-coupled receptor 18 |
| chr5_-_88120083 | 1.16 |
ENST00000509373.1
|
MEF2C
|
myocyte enhancer factor 2C |
| chrX_-_24690771 | 1.15 |
ENST00000379145.1
|
PCYT1B
|
phosphate cytidylyltransferase 1, choline, beta |
| chr15_-_34610962 | 1.14 |
ENST00000290209.5
|
SLC12A6
|
solute carrier family 12 (potassium/chloride transporter), member 6 |
| chr4_+_170581213 | 1.13 |
ENST00000507875.1
|
CLCN3
|
chloride channel, voltage-sensitive 3 |
| chr11_+_22359562 | 1.12 |
ENST00000263160.3
|
SLC17A6
|
solute carrier family 17 (vesicular glutamate transporter), member 6 |
| chr5_-_147162078 | 1.12 |
ENST00000507386.1
|
JAKMIP2
|
janus kinase and microtubule interacting protein 2 |
| chr4_-_109090106 | 1.11 |
ENST00000379951.2
|
LEF1
|
lymphoid enhancer-binding factor 1 |
| chr6_-_56716686 | 1.11 |
ENST00000520645.1
|
DST
|
dystonin |
| chr8_+_79503458 | 1.10 |
ENST00000518467.1
|
PKIA
|
protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| chr10_-_14613968 | 1.10 |
ENST00000488576.1
ENST00000472095.1 |
FAM107B
|
family with sequence similarity 107, member B |
| chr20_-_52612468 | 1.09 |
ENST00000422805.1
|
BCAS1
|
breast carcinoma amplified sequence 1 |
| chr12_+_94542459 | 1.08 |
ENST00000258526.4
|
PLXNC1
|
plexin C1 |
| chr17_+_76037081 | 1.08 |
ENST00000588549.1
|
TNRC6C
|
trinucleotide repeat containing 6C |
| chr8_+_53207015 | 1.08 |
ENST00000522228.1
|
RP11-1023P17.2
|
RP11-1023P17.2 |
| chr10_-_99094458 | 1.07 |
ENST00000371019.2
|
FRAT2
|
frequently rearranged in advanced T-cell lymphomas 2 |
| chr17_-_57229155 | 1.07 |
ENST00000584089.1
|
SKA2
|
spindle and kinetochore associated complex subunit 2 |
| chr15_+_90544532 | 1.07 |
ENST00000268154.4
|
ZNF710
|
zinc finger protein 710 |
| chr3_+_178865887 | 1.06 |
ENST00000477735.1
|
PIK3CA
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| chrX_+_107288239 | 1.06 |
ENST00000217957.5
|
VSIG1
|
V-set and immunoglobulin domain containing 1 |
| chr10_-_14614311 | 1.05 |
ENST00000479731.1
ENST00000468492.1 |
FAM107B
|
family with sequence similarity 107, member B |
| chr14_+_22951276 | 1.05 |
ENST00000390484.1
|
TRAJ54
|
T cell receptor alpha joining 54 |
| chr2_+_27070964 | 1.05 |
ENST00000288699.6
|
DPYSL5
|
dihydropyrimidinase-like 5 |
| chr1_-_156217822 | 1.04 |
ENST00000368270.1
|
PAQR6
|
progestin and adipoQ receptor family member VI |
| chr5_+_133859996 | 1.03 |
ENST00000512386.1
|
PHF15
|
jade family PHD finger 2 |
| chr5_+_137673200 | 1.01 |
ENST00000434981.2
|
FAM53C
|
family with sequence similarity 53, member C |
| chr1_-_156217875 | 1.01 |
ENST00000292291.5
|
PAQR6
|
progestin and adipoQ receptor family member VI |
| chr7_+_106505696 | 1.00 |
ENST00000440650.2
ENST00000496166.1 ENST00000473541.1 |
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr16_-_4852915 | 1.00 |
ENST00000322048.7
|
ROGDI
|
rogdi homolog (Drosophila) |
| chr7_+_29519662 | 0.99 |
ENST00000424025.2
ENST00000439711.2 ENST00000421775.2 |
CHN2
|
chimerin 2 |
| chr5_-_41794663 | 0.99 |
ENST00000510634.1
|
OXCT1
|
3-oxoacid CoA transferase 1 |
| chr10_-_14614122 | 0.98 |
ENST00000378465.3
ENST00000452706.2 ENST00000378458.2 |
FAM107B
|
family with sequence similarity 107, member B |
| chr1_-_156217829 | 0.98 |
ENST00000356983.2
ENST00000335852.1 ENST00000340183.5 ENST00000540423.1 |
PAQR6
|
progestin and adipoQ receptor family member VI |
| chr14_+_22748980 | 0.98 |
ENST00000390465.2
|
TRAV38-2DV8
|
T cell receptor alpha variable 38-2/delta variable 8 |
| chr5_+_173930710 | 0.97 |
ENST00000511707.1
|
RP11-267A15.1
|
RP11-267A15.1 |
| chr16_+_6069586 | 0.97 |
ENST00000547372.1
|
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr17_-_49124230 | 0.97 |
ENST00000510283.1
ENST00000510855.1 |
SPAG9
|
sperm associated antigen 9 |
| chr1_-_177134024 | 0.96 |
ENST00000367654.3
|
ASTN1
|
astrotactin 1 |
| chr13_-_74708372 | 0.96 |
ENST00000377666.4
|
KLF12
|
Kruppel-like factor 12 |
| chr6_-_108145499 | 0.95 |
ENST00000369020.3
ENST00000369022.2 |
SCML4
|
sex comb on midleg-like 4 (Drosophila) |
| chr7_+_129015484 | 0.95 |
ENST00000490911.1
|
AHCYL2
|
adenosylhomocysteinase-like 2 |
| chr10_-_14614095 | 0.94 |
ENST00000482277.1
ENST00000378462.1 |
FAM107B
|
family with sequence similarity 107, member B |
| chr10_+_11207438 | 0.94 |
ENST00000609692.1
ENST00000354897.3 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr14_+_22982921 | 0.93 |
ENST00000390508.1
|
TRAJ29
|
T cell receptor alpha joining 29 |
| chr4_-_109089573 | 0.93 |
ENST00000265165.1
|
LEF1
|
lymphoid enhancer-binding factor 1 |
| chr7_+_30185406 | 0.93 |
ENST00000324489.5
|
C7orf41
|
maturin, neural progenitor differentiation regulator homolog (Xenopus) |
| chr2_+_27071045 | 0.92 |
ENST00000401478.1
|
DPYSL5
|
dihydropyrimidinase-like 5 |
| chr12_-_75603202 | 0.92 |
ENST00000393288.2
|
KCNC2
|
potassium voltage-gated channel, Shaw-related subfamily, member 2 |
| chr6_+_98264571 | 0.90 |
ENST00000607823.1
|
RP11-436D23.1
|
RP11-436D23.1 |
| chr12_-_24715307 | 0.90 |
ENST00000538905.1
|
RP11-444D3.1
|
RP11-444D3.1 |
| chr20_-_21494654 | 0.90 |
ENST00000377142.4
|
NKX2-2
|
NK2 homeobox 2 |
| chr2_+_181988620 | 0.90 |
ENST00000428474.1
ENST00000424655.1 |
AC104820.2
|
AC104820.2 |
| chr5_-_11589131 | 0.89 |
ENST00000511377.1
|
CTNND2
|
catenin (cadherin-associated protein), delta 2 |
| chr10_+_111967345 | 0.88 |
ENST00000332674.5
ENST00000453116.1 |
MXI1
|
MAX interactor 1, dimerization protein |
| chr1_-_177133998 | 0.88 |
ENST00000367657.3
|
ASTN1
|
astrotactin 1 |
| chr1_-_177133818 | 0.88 |
ENST00000424564.2
ENST00000361833.2 |
ASTN1
|
astrotactin 1 |
| chr13_-_99910673 | 0.87 |
ENST00000397473.2
ENST00000397470.2 |
GPR18
|
G protein-coupled receptor 18 |
| chr7_+_106505912 | 0.86 |
ENST00000359195.3
|
PIK3CG
|
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| chr12_-_12674032 | 0.86 |
ENST00000298573.4
|
DUSP16
|
dual specificity phosphatase 16 |
| chr1_+_40840320 | 0.86 |
ENST00000372708.1
|
SMAP2
|
small ArfGAP2 |
| chr2_-_166060552 | 0.85 |
ENST00000283254.7
ENST00000453007.1 |
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chr10_-_62332357 | 0.84 |
ENST00000503366.1
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr18_+_72201664 | 0.83 |
ENST00000358821.3
|
CNDP1
|
carnosine dipeptidase 1 (metallopeptidase M20 family) |
| chr18_+_55024383 | 0.83 |
ENST00000586360.1
|
ST8SIA3
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| chr2_+_120517174 | 0.83 |
ENST00000263708.2
|
PTPN4
|
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| chr4_-_53522703 | 0.83 |
ENST00000508499.1
|
USP46
|
ubiquitin specific peptidase 46 |
| chr10_+_11207485 | 0.83 |
ENST00000537122.1
|
CELF2
|
CUGBP, Elav-like family member 2 |
| chr14_-_70038032 | 0.82 |
ENST00000543986.1
|
CCDC177
|
coiled-coil domain containing 177 |
| chr7_+_30185496 | 0.82 |
ENST00000455738.1
|
C7orf41
|
maturin, neural progenitor differentiation regulator homolog (Xenopus) |
| chr11_-_46141338 | 0.82 |
ENST00000529782.1
ENST00000532010.1 ENST00000525438.1 ENST00000533757.1 ENST00000527782.1 |
PHF21A
|
PHD finger protein 21A |
| chr8_+_77316233 | 0.82 |
ENST00000603284.1
ENST00000603837.1 |
RP11-706J10.2
RP11-706J10.3
|
RP11-706J10.2 long intergenic non-protein coding RNA 1109 |
| chr11_-_82708519 | 0.82 |
ENST00000534301.1
|
RAB30
|
RAB30, member RAS oncogene family |
| chr22_+_40297105 | 0.81 |
ENST00000540310.1
|
GRAP2
|
GRB2-related adaptor protein 2 |
| chr2_-_166060382 | 0.80 |
ENST00000409101.3
|
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chr16_+_6069072 | 0.80 |
ENST00000547605.1
ENST00000550418.1 ENST00000553186.1 |
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr5_-_65018834 | 0.80 |
ENST00000506816.1
|
SGTB
|
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta |
| chr3_-_33700589 | 0.78 |
ENST00000461133.3
ENST00000496954.2 |
CLASP2
|
cytoplasmic linker associated protein 2 |
| chr1_+_100316041 | 0.77 |
ENST00000370165.3
ENST00000370163.3 ENST00000294724.4 |
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| chr9_-_123476612 | 0.77 |
ENST00000426959.1
|
MEGF9
|
multiple EGF-like-domains 9 |
| chr2_+_149447783 | 0.77 |
ENST00000449013.1
|
EPC2
|
enhancer of polycomb homolog 2 (Drosophila) |
| chr1_-_102312600 | 0.77 |
ENST00000359814.3
|
OLFM3
|
olfactomedin 3 |
| chr7_+_129015671 | 0.77 |
ENST00000466993.1
|
AHCYL2
|
adenosylhomocysteinase-like 2 |
| chr10_-_62149433 | 0.76 |
ENST00000280772.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr21_-_19191703 | 0.76 |
ENST00000284881.4
ENST00000400559.3 ENST00000400558.3 |
C21orf91
|
chromosome 21 open reading frame 91 |
| chr12_-_498415 | 0.76 |
ENST00000535014.1
ENST00000543507.1 ENST00000544760.1 |
KDM5A
|
lysine (K)-specific demethylase 5A |
| chr4_-_185395191 | 0.76 |
ENST00000510814.1
ENST00000507523.1 ENST00000506230.1 |
IRF2
|
interferon regulatory factor 2 |
| chr3_-_62358690 | 0.76 |
ENST00000475839.1
|
FEZF2
|
FEZ family zinc finger 2 |
| chr1_-_160231451 | 0.75 |
ENST00000495887.1
|
DCAF8
|
DDB1 and CUL4 associated factor 8 |
| chr14_-_23904861 | 0.74 |
ENST00000355349.3
|
MYH7
|
myosin, heavy chain 7, cardiac muscle, beta |
| chr11_-_82708435 | 0.74 |
ENST00000525117.1
ENST00000532548.1 |
RAB30
|
RAB30, member RAS oncogene family |
| chr1_-_102312517 | 0.72 |
ENST00000338858.5
|
OLFM3
|
olfactomedin 3 |
| chr17_+_79953310 | 0.72 |
ENST00000582355.2
|
ASPSCR1
|
alveolar soft part sarcoma chromosome region, candidate 1 |
| chr20_+_18125727 | 0.72 |
ENST00000489634.2
|
CSRP2BP
|
CSRP2 binding protein |
| chr12_+_498545 | 0.72 |
ENST00000543504.1
|
CCDC77
|
coiled-coil domain containing 77 |
| chr11_-_13461790 | 0.72 |
ENST00000530907.1
|
BTBD10
|
BTB (POZ) domain containing 10 |
| chr11_-_118095718 | 0.71 |
ENST00000526620.1
|
AMICA1
|
adhesion molecule, interacts with CXADR antigen 1 |
| chr1_+_66797687 | 0.70 |
ENST00000371045.5
ENST00000531025.1 ENST00000526197.1 |
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr12_-_76817036 | 0.69 |
ENST00000546946.1
|
OSBPL8
|
oxysterol binding protein-like 8 |
| chr11_-_118095801 | 0.68 |
ENST00000356289.5
|
AMICA1
|
adhesion molecule, interacts with CXADR antigen 1 |
| chr12_+_498500 | 0.68 |
ENST00000540180.1
ENST00000422000.1 ENST00000535052.1 |
CCDC77
|
coiled-coil domain containing 77 |
| chr2_-_160472952 | 0.68 |
ENST00000541068.2
ENST00000355831.2 ENST00000343439.5 ENST00000392782.1 |
BAZ2B
|
bromodomain adjacent to zinc finger domain, 2B |
| chr5_+_137673945 | 0.67 |
ENST00000513056.1
ENST00000511276.1 |
FAM53C
|
family with sequence similarity 53, member C |
| chr3_-_33700933 | 0.67 |
ENST00000480013.1
|
CLASP2
|
cytoplasmic linker associated protein 2 |
| chr16_+_53469525 | 0.66 |
ENST00000544405.2
|
RBL2
|
retinoblastoma-like 2 (p130) |
| chr5_-_24645078 | 0.66 |
ENST00000264463.4
|
CDH10
|
cadherin 10, type 2 (T2-cadherin) |
| chr2_-_160473114 | 0.66 |
ENST00000392783.2
|
BAZ2B
|
bromodomain adjacent to zinc finger domain, 2B |
| chr3_-_28389922 | 0.65 |
ENST00000415852.1
|
AZI2
|
5-azacytidine induced 2 |
| chr10_+_70847852 | 0.65 |
ENST00000242465.3
|
SRGN
|
serglycin |
| chr10_-_61900762 | 0.65 |
ENST00000355288.2
|
ANK3
|
ankyrin 3, node of Ranvier (ankyrin G) |
| chr3_-_62359180 | 0.65 |
ENST00000283268.3
|
FEZF2
|
FEZ family zinc finger 2 |
| chr12_-_498620 | 0.64 |
ENST00000399788.2
ENST00000382815.4 |
KDM5A
|
lysine (K)-specific demethylase 5A |
| chr18_+_72201829 | 0.64 |
ENST00000582365.1
|
CNDP1
|
carnosine dipeptidase 1 (metallopeptidase M20 family) |
| chr11_+_128563652 | 0.64 |
ENST00000527786.2
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr11_+_36317830 | 0.64 |
ENST00000530639.1
|
PRR5L
|
proline rich 5 like |
| chr6_-_116866773 | 0.63 |
ENST00000368602.3
|
TRAPPC3L
|
trafficking protein particle complex 3-like |
| chr9_-_123476719 | 0.63 |
ENST00000373930.3
|
MEGF9
|
multiple EGF-like-domains 9 |
| chr6_-_152489484 | 0.63 |
ENST00000354674.4
ENST00000539504.1 |
SYNE1
|
spectrin repeat containing, nuclear envelope 1 |
| chr6_+_84563295 | 0.63 |
ENST00000369687.1
|
RIPPLY2
|
ripply transcriptional repressor 2 |
| chr2_-_166060571 | 0.63 |
ENST00000360093.3
|
SCN3A
|
sodium channel, voltage-gated, type III, alpha subunit |
| chr11_-_125351481 | 0.62 |
ENST00000577924.1
|
FEZ1
|
fasciculation and elongation protein zeta 1 (zygin I) |
| chr2_+_86668464 | 0.62 |
ENST00000409064.1
|
KDM3A
|
lysine (K)-specific demethylase 3A |
| chr4_+_24661479 | 0.62 |
ENST00000569621.1
|
RP11-496D24.2
|
RP11-496D24.2 |
| chr8_-_133071627 | 0.62 |
ENST00000443356.2
ENST00000603859.1 ENST00000254627.3 |
OC90
OC90
|
Otoconin-90 otoconin 90 |
| chr1_-_108231101 | 0.62 |
ENST00000544443.1
ENST00000415432.2 |
VAV3
|
vav 3 guanine nucleotide exchange factor |
| chr3_+_57882061 | 0.61 |
ENST00000461354.1
ENST00000466255.1 |
SLMAP
|
sarcolemma associated protein |
| chr2_-_192711968 | 0.61 |
ENST00000304141.4
|
SDPR
|
serum deprivation response |
| chr17_+_6658878 | 0.61 |
ENST00000574394.1
|
XAF1
|
XIAP associated factor 1 |
| chr7_+_7811992 | 0.60 |
ENST00000406829.1
|
RPA3-AS1
|
RPA3 antisense RNA 1 |
| chr8_+_85095497 | 0.59 |
ENST00000522455.1
ENST00000521695.1 |
RALYL
|
RALY RNA binding protein-like |
| chr14_-_55878538 | 0.59 |
ENST00000247178.5
|
ATG14
|
autophagy related 14 |
| chr8_+_24151553 | 0.59 |
ENST00000265769.4
ENST00000540823.1 ENST00000397649.3 |
ADAM28
|
ADAM metallopeptidase domain 28 |
| chr16_-_69390209 | 0.59 |
ENST00000563634.1
|
RP11-343C2.9
|
Uncharacterized protein |
| chr7_+_29519486 | 0.58 |
ENST00000409041.4
|
CHN2
|
chimerin 2 |
| chr2_+_86947296 | 0.58 |
ENST00000283632.4
|
RMND5A
|
required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| chr9_-_23826298 | 0.57 |
ENST00000380117.1
|
ELAVL2
|
ELAV like neuron-specific RNA binding protein 2 |
| chr2_+_191273052 | 0.57 |
ENST00000417958.1
ENST00000432036.1 ENST00000392328.1 |
MFSD6
|
major facilitator superfamily domain containing 6 |
| chr14_+_58894404 | 0.57 |
ENST00000554463.1
ENST00000555833.1 |
KIAA0586
|
KIAA0586 |
| chr6_-_42418999 | 0.56 |
ENST00000340840.2
ENST00000354325.2 |
TRERF1
|
transcriptional regulating factor 1 |
| chr14_+_22988947 | 0.56 |
ENST00000390513.1
|
TRAJ24
|
T cell receptor alpha joining 24 |
| chr12_+_42725554 | 0.56 |
ENST00000546750.1
ENST00000547847.1 |
PPHLN1
|
periphilin 1 |
| chr20_-_43150601 | 0.55 |
ENST00000541235.1
ENST00000255175.1 ENST00000342374.4 |
SERINC3
|
serine incorporator 3 |
| chr8_-_116673894 | 0.55 |
ENST00000395713.2
|
TRPS1
|
trichorhinophalangeal syndrome I |
| chr16_-_68482440 | 0.55 |
ENST00000219334.5
|
SMPD3
|
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
Network of associatons between targets according to the STRING database.
First level regulatory network of SRY
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.2 | GO:0010693 | negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.7 | 7.0 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.5 | 1.6 | GO:1904346 | positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) |
| 0.5 | 5.8 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.5 | 2.0 | GO:0002304 | gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305) |
| 0.5 | 1.9 | GO:0032252 | secretory granule localization(GO:0032252) |
| 0.5 | 7.7 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.4 | 2.3 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 10.6 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.4 | 1.4 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.3 | 2.1 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.3 | 2.4 | GO:0003138 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.3 | 2.4 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.3 | 0.9 | GO:0021530 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.3 | 2.0 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.3 | 1.4 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.3 | 1.7 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 1.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.2 | 0.9 | GO:0044029 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.2 | 1.1 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.2 | 1.4 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.2 | 0.7 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.2 | 0.9 | GO:0045209 | MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209) |
| 0.2 | 1.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 1.1 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.2 | 0.7 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 0.2 | 0.5 | GO:0019082 | viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.2 | 0.5 | GO:1904585 | response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828) |
| 0.2 | 0.5 | GO:0042245 | RNA repair(GO:0042245) |
| 0.2 | 4.6 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.1 | 0.6 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.1 | 1.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 1.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.5 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 0.1 | 0.5 | GO:0003162 | atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928) |
| 0.1 | 1.6 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.6 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.1 | 1.0 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.4 | GO:0097198 | histone H3-K36 trimethylation(GO:0097198) |
| 0.1 | 0.6 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.1 | 0.9 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.1 | 6.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 1.1 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.1 | 1.0 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 0.8 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 1.2 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 1.4 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.1 | 1.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 2.7 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.4 | GO:0045354 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) |
| 0.1 | 1.3 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.1 | 0.3 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.1 | 0.2 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 0.6 | GO:0009597 | detection of virus(GO:0009597) |
| 0.1 | 0.3 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 0.1 | 0.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 0.8 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.1 | 1.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 1.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 2.3 | GO:1904886 | beta-catenin destruction complex disassembly(GO:1904886) |
| 0.1 | 0.9 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 1.9 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.1 | 0.4 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.1 | 0.4 | GO:1901631 | postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.1 | 1.2 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.1 | 0.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.1 | 0.5 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.9 | GO:1901078 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.1 | 0.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.1 | 1.4 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.1 | 0.4 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.1 | 0.3 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.1 | 0.2 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.2 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.1 | 8.7 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 0.8 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 1.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 0.6 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 0.0 | 1.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.8 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 1.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.4 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.0 | 0.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.3 | GO:0045588 | positive regulation of gamma-delta T cell differentiation(GO:0045588) |
| 0.0 | 0.3 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.0 | 0.6 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 0.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.5 | GO:0031442 | positive regulation of mRNA 3'-end processing(GO:0031442) |
| 0.0 | 0.7 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 1.0 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
| 0.0 | 1.2 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.3 | GO:0021559 | trigeminal nerve development(GO:0021559) |
| 0.0 | 0.7 | GO:0033500 | carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) |
| 0.0 | 0.8 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.6 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 2.4 | GO:0006536 | glutamate metabolic process(GO:0006536) |
| 0.0 | 0.6 | GO:0043578 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.0 | 1.9 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.1 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.0 | 0.4 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.1 | GO:0033385 | geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386) |
| 0.0 | 0.4 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.0 | 1.3 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 1.7 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.0 | 0.5 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.3 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
| 0.0 | 0.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.0 | 0.1 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 1.1 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.2 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.0 | 0.1 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.0 | 0.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.6 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 0.0 | 0.4 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.8 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.0 | 0.1 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.0 | 0.4 | GO:0035886 | vascular smooth muscle cell differentiation(GO:0035886) |
| 0.0 | 1.0 | GO:0007420 | brain development(GO:0007420) |
| 0.0 | 0.3 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 0.8 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.2 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.0 | 0.2 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.0 | 0.6 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.0 | 0.1 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
| 0.0 | 0.2 | GO:0008037 | cell recognition(GO:0008037) |
| 0.0 | 0.6 | GO:0030890 | positive regulation of B cell proliferation(GO:0030890) |
| 0.0 | 0.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 1.3 | GO:0031295 | T cell costimulation(GO:0031295) |
| 0.0 | 0.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.2 | GO:0034374 | low-density lipoprotein particle remodeling(GO:0034374) |
| 0.0 | 0.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.9 | GO:0005944 | phosphatidylinositol 3-kinase complex, class IB(GO:0005944) |
| 0.3 | 7.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.3 | 1.0 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.2 | 10.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 0.6 | GO:0034657 | GID complex(GO:0034657) |
| 0.2 | 1.1 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 2.0 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 6.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 1.4 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.1 | 1.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.3 | GO:0043614 | multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451) |
| 0.1 | 2.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 1.4 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 2.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 0.9 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.1 | 2.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 1.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.4 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.1 | 0.5 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.7 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.5 | GO:0072487 | MSL complex(GO:0072487) |
| 0.0 | 0.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.6 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.2 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.0 | 1.2 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 0.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 1.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 7.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 6.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.8 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.6 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 2.1 | GO:0044304 | main axon(GO:0044304) |
| 0.0 | 1.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 4.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.4 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 1.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.5 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 1.8 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.1 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.7 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.8 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.8 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 0.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.8 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 1.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.8 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.5 | 1.6 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.5 | 1.6 | GO:0031768 | ghrelin receptor binding(GO:0031768) |
| 0.5 | 1.4 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.4 | 7.7 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.4 | 1.4 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.3 | 2.4 | GO:0047820 | D-glutamate cyclase activity(GO:0047820) |
| 0.3 | 7.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.3 | 3.1 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.3 | 0.8 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 0.2 | 1.0 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.2 | 1.7 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.2 | 1.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.2 | 1.1 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.2 | 4.2 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 0.5 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.1 | 0.5 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.1 | 2.0 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.1 | 1.9 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 1.0 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 6.5 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 4.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 0.3 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.1 | 1.1 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.6 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 0.4 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.1 | 0.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 10.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 1.3 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.1 | 0.4 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.1 | 2.3 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.5 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 8.0 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 2.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.8 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 0.1 | 2.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 1.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 1.1 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.1 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.4 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.0 | 0.2 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.6 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.9 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.2 | GO:0015278 | calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604) |
| 0.0 | 0.5 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.0 | 1.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.6 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 1.5 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 2.3 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.7 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.6 | GO:0051020 | GTPase binding(GO:0051020) |
| 0.0 | 1.2 | GO:0030371 | translation repressor activity(GO:0030371) |
| 0.0 | 0.9 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 1.3 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.3 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.0 | 0.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 1.6 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.0 | 0.1 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.0 | 0.4 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.0 | 0.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.8 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.1 | GO:0004161 | dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337) |
| 0.0 | 0.6 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.6 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 2.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.0 | 3.5 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 6.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 1.4 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.4 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.5 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.2 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.0 | 1.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 1.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.2 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.1 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 0.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 0.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 8.2 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 2.5 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 2.1 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.1 | 8.2 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 0.6 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.9 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 2.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.6 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 1.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 3.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.0 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.5 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.0 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 1.6 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 1.3 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.4 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.6 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.8 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.0 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.1 | 7.9 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.1 | 2.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.1 | 4.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 4.8 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.1 | 1.4 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 7.3 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 2.3 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 1.6 | REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 2.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.4 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 0.0 | 1.4 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.6 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 1.2 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |
| 0.0 | 1.2 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 1.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.9 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 3.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.8 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 2.8 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 0.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.9 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.0 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.4 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.3 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 1.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |