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Illumina Body Map 2, young vs old

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Results for SRY

Z-value: 0.37

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
ENSG00000184895.6 sex determining region Y

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg19_v2_chrY_-_2655644_2655740-0.144.4e-01Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39509070 4.42 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
myelin-associated oligodendrocyte basic protein
chr11_+_112832090 3.85 ENST00000533760.1
neural cell adhesion molecule 1
chr8_+_67405794 3.54 ENST00000522977.1
ENST00000480005.1
chromosome 8 open reading frame 46
chr3_+_39509163 3.24 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
myelin-associated oligodendrocyte basic protein
chr8_+_67405755 3.16 ENST00000521495.1
chromosome 8 open reading frame 46
chr5_-_146435572 2.95 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr5_-_146435694 2.90 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr2_-_2334888 2.84 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chr5_-_146435501 2.69 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr10_+_11206925 2.49 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chrX_+_107288280 2.38 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr7_+_28452130 2.34 ENST00000357727.2
cAMP responsive element binding protein 5
chr9_-_92051391 2.18 ENST00000420681.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr5_-_146461027 2.07 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
protein phosphatase 2, regulatory subunit B, beta
chr11_+_112832133 2.07 ENST00000524665.1
neural cell adhesion molecule 1
chr9_-_92051354 2.07 ENST00000418828.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr21_-_32931290 2.06 ENST00000286827.3
T-cell lymphoma invasion and metastasis 1
chr12_-_62586543 2.04 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr5_-_111091948 2.03 ENST00000447165.2
neuronal regeneration related protein
chr11_+_112832202 2.03 ENST00000534015.1
neural cell adhesion molecule 1
chr14_-_60097297 2.01 ENST00000395090.1
reticulon 1
chr11_-_35441524 1.98 ENST00000395750.1
ENST00000449068.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_147162263 1.97 ENST00000333010.6
ENST00000265272.5
janus kinase and microtubule interacting protein 2
chr11_-_35441597 1.91 ENST00000395753.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_-_35440796 1.88 ENST00000278379.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_-_121973974 1.68 ENST00000538379.1
ENST00000541318.1
ENST00000541511.1
lysine (K)-specific demethylase 2B
chr10_+_11207088 1.68 ENST00000608830.1
CUGBP, Elav-like family member 2
chr1_-_40367668 1.64 ENST00000397332.2
ENST00000429311.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr1_-_193155729 1.64 ENST00000367434.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_-_164534657 1.62 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr11_-_46848393 1.60 ENST00000526496.1
cytoskeleton associated protein 5
chr1_+_84630352 1.60 ENST00000450730.1
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_10332416 1.60 ENST00000450603.1
ENST00000449554.2
ghrelin/obestatin prepropeptide
chr1_+_50574585 1.51 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr20_-_52612705 1.51 ENST00000434986.2
breast carcinoma amplified sequence 1
chr14_+_22994472 1.50 ENST00000390519.1
T cell receptor alpha joining 18
chr5_+_173930676 1.48 ENST00000504512.1
RP11-267A15.1
chr1_-_40367530 1.41 ENST00000372816.2
ENST00000372815.1
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr17_-_37764128 1.41 ENST00000302584.4
neuronal differentiation 2
chrX_-_19689106 1.41 ENST00000379716.1
SH3-domain kinase binding protein 1
chr20_-_52645231 1.39 ENST00000448484.1
breast carcinoma amplified sequence 1
chr22_+_19710468 1.38 ENST00000366425.3
glycoprotein Ib (platelet), beta polypeptide
chr1_+_84630645 1.38 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_84630574 1.36 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_71353892 1.36 ENST00000484350.1
forkhead box P1
chr1_+_50571949 1.35 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr1_+_84630053 1.35 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr14_-_89960395 1.35 ENST00000555034.1
ENST00000553904.1
forkhead box N3
chrX_+_28605516 1.33 ENST00000378993.1
interleukin 1 receptor accessory protein-like 1
chr1_+_84630367 1.32 ENST00000370680.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_181988560 1.32 ENST00000424170.1
ENST00000435411.1
AC104820.2
chr10_+_99079008 1.26 ENST00000371021.3
frequently rearranged in advanced T-cell lymphomas
chr5_-_88120151 1.24 ENST00000506716.1
myocyte enhancer factor 2C
chr13_-_114843416 1.22 ENST00000389544.4
RAS p21 protein activator 3
chrX_+_107288197 1.19 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr13_-_46716969 1.19 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr8_-_124553437 1.18 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr13_-_99910620 1.16 ENST00000416594.1
G protein-coupled receptor 18
chr5_-_88120083 1.16 ENST00000509373.1
myocyte enhancer factor 2C
chrX_-_24690771 1.15 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr15_-_34610962 1.14 ENST00000290209.5
solute carrier family 12 (potassium/chloride transporter), member 6
chr4_+_170581213 1.13 ENST00000507875.1
chloride channel, voltage-sensitive 3
chr11_+_22359562 1.12 ENST00000263160.3
solute carrier family 17 (vesicular glutamate transporter), member 6
chr5_-_147162078 1.12 ENST00000507386.1
janus kinase and microtubule interacting protein 2
chr4_-_109090106 1.11 ENST00000379951.2
lymphoid enhancer-binding factor 1
chr6_-_56716686 1.11 ENST00000520645.1
dystonin
chr8_+_79503458 1.10 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr10_-_14613968 1.10 ENST00000488576.1
ENST00000472095.1
family with sequence similarity 107, member B
chr20_-_52612468 1.09 ENST00000422805.1
breast carcinoma amplified sequence 1
chr12_+_94542459 1.08 ENST00000258526.4
plexin C1
chr17_+_76037081 1.08 ENST00000588549.1
trinucleotide repeat containing 6C
chr8_+_53207015 1.08 ENST00000522228.1
RP11-1023P17.2
chr10_-_99094458 1.07 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr17_-_57229155 1.07 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr15_+_90544532 1.07 ENST00000268154.4
zinc finger protein 710
chr3_+_178865887 1.06 ENST00000477735.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chrX_+_107288239 1.06 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr10_-_14614311 1.05 ENST00000479731.1
ENST00000468492.1
family with sequence similarity 107, member B
chr14_+_22951276 1.05 ENST00000390484.1
T cell receptor alpha joining 54
chr2_+_27070964 1.05 ENST00000288699.6
dihydropyrimidinase-like 5
chr1_-_156217822 1.04 ENST00000368270.1
progestin and adipoQ receptor family member VI
chr5_+_133859996 1.03 ENST00000512386.1
jade family PHD finger 2
chr5_+_137673200 1.01 ENST00000434981.2
family with sequence similarity 53, member C
chr1_-_156217875 1.01 ENST00000292291.5
progestin and adipoQ receptor family member VI
chr7_+_106505696 1.00 ENST00000440650.2
ENST00000496166.1
ENST00000473541.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr16_-_4852915 1.00 ENST00000322048.7
rogdi homolog (Drosophila)
chr7_+_29519662 0.99 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
chimerin 2
chr5_-_41794663 0.99 ENST00000510634.1
3-oxoacid CoA transferase 1
chr10_-_14614122 0.98 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
family with sequence similarity 107, member B
chr1_-_156217829 0.98 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
progestin and adipoQ receptor family member VI
chr14_+_22748980 0.98 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr5_+_173930710 0.97 ENST00000511707.1
RP11-267A15.1
chr16_+_6069586 0.97 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_-_49124230 0.97 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr1_-_177134024 0.96 ENST00000367654.3
astrotactin 1
chr13_-_74708372 0.96 ENST00000377666.4
Kruppel-like factor 12
chr6_-_108145499 0.95 ENST00000369020.3
ENST00000369022.2
sex comb on midleg-like 4 (Drosophila)
chr7_+_129015484 0.95 ENST00000490911.1
adenosylhomocysteinase-like 2
chr10_-_14614095 0.94 ENST00000482277.1
ENST00000378462.1
family with sequence similarity 107, member B
chr10_+_11207438 0.94 ENST00000609692.1
ENST00000354897.3
CUGBP, Elav-like family member 2
chr14_+_22982921 0.93 ENST00000390508.1
T cell receptor alpha joining 29
chr4_-_109089573 0.93 ENST00000265165.1
lymphoid enhancer-binding factor 1
chr7_+_30185406 0.93 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_+_27071045 0.92 ENST00000401478.1
dihydropyrimidinase-like 5
chr12_-_75603202 0.92 ENST00000393288.2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr6_+_98264571 0.90 ENST00000607823.1
RP11-436D23.1
chr12_-_24715307 0.90 ENST00000538905.1
RP11-444D3.1
chr20_-_21494654 0.90 ENST00000377142.4
NK2 homeobox 2
chr2_+_181988620 0.90 ENST00000428474.1
ENST00000424655.1
AC104820.2
chr5_-_11589131 0.89 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr10_+_111967345 0.88 ENST00000332674.5
ENST00000453116.1
MAX interactor 1, dimerization protein
chr1_-_177133998 0.88 ENST00000367657.3
astrotactin 1
chr1_-_177133818 0.88 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr13_-_99910673 0.87 ENST00000397473.2
ENST00000397470.2
G protein-coupled receptor 18
chr7_+_106505912 0.86 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr12_-_12674032 0.86 ENST00000298573.4
dual specificity phosphatase 16
chr1_+_40840320 0.86 ENST00000372708.1
small ArfGAP2
chr2_-_166060552 0.85 ENST00000283254.7
ENST00000453007.1
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_62332357 0.84 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr18_+_72201664 0.83 ENST00000358821.3
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr18_+_55024383 0.83 ENST00000586360.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_120517174 0.83 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr4_-_53522703 0.83 ENST00000508499.1
ubiquitin specific peptidase 46
chr10_+_11207485 0.83 ENST00000537122.1
CUGBP, Elav-like family member 2
chr14_-_70038032 0.82 ENST00000543986.1
coiled-coil domain containing 177
chr7_+_30185496 0.82 ENST00000455738.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr11_-_46141338 0.82 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHD finger protein 21A
chr8_+_77316233 0.82 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr11_-_82708519 0.82 ENST00000534301.1
RAB30, member RAS oncogene family
chr22_+_40297105 0.81 ENST00000540310.1
GRB2-related adaptor protein 2
chr2_-_166060382 0.80 ENST00000409101.3
sodium channel, voltage-gated, type III, alpha subunit
chr16_+_6069072 0.80 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_65018834 0.80 ENST00000506816.1
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr3_-_33700589 0.78 ENST00000461133.3
ENST00000496954.2
cytoplasmic linker associated protein 2
chr1_+_100316041 0.77 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr9_-_123476612 0.77 ENST00000426959.1
multiple EGF-like-domains 9
chr2_+_149447783 0.77 ENST00000449013.1
enhancer of polycomb homolog 2 (Drosophila)
chr1_-_102312600 0.77 ENST00000359814.3
olfactomedin 3
chr7_+_129015671 0.77 ENST00000466993.1
adenosylhomocysteinase-like 2
chr10_-_62149433 0.76 ENST00000280772.2
ankyrin 3, node of Ranvier (ankyrin G)
chr21_-_19191703 0.76 ENST00000284881.4
ENST00000400559.3
ENST00000400558.3
chromosome 21 open reading frame 91
chr12_-_498415 0.76 ENST00000535014.1
ENST00000543507.1
ENST00000544760.1
lysine (K)-specific demethylase 5A
chr4_-_185395191 0.76 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr3_-_62358690 0.76 ENST00000475839.1
FEZ family zinc finger 2
chr1_-_160231451 0.75 ENST00000495887.1
DDB1 and CUL4 associated factor 8
chr14_-_23904861 0.74 ENST00000355349.3
myosin, heavy chain 7, cardiac muscle, beta
chr11_-_82708435 0.74 ENST00000525117.1
ENST00000532548.1
RAB30, member RAS oncogene family
chr1_-_102312517 0.72 ENST00000338858.5
olfactomedin 3
chr17_+_79953310 0.72 ENST00000582355.2
alveolar soft part sarcoma chromosome region, candidate 1
chr20_+_18125727 0.72 ENST00000489634.2
CSRP2 binding protein
chr12_+_498545 0.72 ENST00000543504.1
coiled-coil domain containing 77
chr11_-_13461790 0.72 ENST00000530907.1
BTB (POZ) domain containing 10
chr11_-_118095718 0.71 ENST00000526620.1
adhesion molecule, interacts with CXADR antigen 1
chr1_+_66797687 0.70 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr12_-_76817036 0.69 ENST00000546946.1
oxysterol binding protein-like 8
chr11_-_118095801 0.68 ENST00000356289.5
adhesion molecule, interacts with CXADR antigen 1
chr12_+_498500 0.68 ENST00000540180.1
ENST00000422000.1
ENST00000535052.1
coiled-coil domain containing 77
chr2_-_160472952 0.68 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
bromodomain adjacent to zinc finger domain, 2B
chr5_+_137673945 0.67 ENST00000513056.1
ENST00000511276.1
family with sequence similarity 53, member C
chr3_-_33700933 0.67 ENST00000480013.1
cytoplasmic linker associated protein 2
chr16_+_53469525 0.66 ENST00000544405.2
retinoblastoma-like 2 (p130)
chr5_-_24645078 0.66 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr2_-_160473114 0.66 ENST00000392783.2
bromodomain adjacent to zinc finger domain, 2B
chr3_-_28389922 0.65 ENST00000415852.1
5-azacytidine induced 2
chr10_+_70847852 0.65 ENST00000242465.3
serglycin
chr10_-_61900762 0.65 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr3_-_62359180 0.65 ENST00000283268.3
FEZ family zinc finger 2
chr12_-_498620 0.64 ENST00000399788.2
ENST00000382815.4
lysine (K)-specific demethylase 5A
chr18_+_72201829 0.64 ENST00000582365.1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr11_+_128563652 0.64 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_36317830 0.64 ENST00000530639.1
proline rich 5 like
chr6_-_116866773 0.63 ENST00000368602.3
trafficking protein particle complex 3-like
chr9_-_123476719 0.63 ENST00000373930.3
multiple EGF-like-domains 9
chr6_-_152489484 0.63 ENST00000354674.4
ENST00000539504.1
spectrin repeat containing, nuclear envelope 1
chr6_+_84563295 0.63 ENST00000369687.1
ripply transcriptional repressor 2
chr2_-_166060571 0.63 ENST00000360093.3
sodium channel, voltage-gated, type III, alpha subunit
chr11_-_125351481 0.62 ENST00000577924.1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_+_86668464 0.62 ENST00000409064.1
lysine (K)-specific demethylase 3A
chr4_+_24661479 0.62 ENST00000569621.1
RP11-496D24.2
chr8_-_133071627 0.62 ENST00000443356.2
ENST00000603859.1
ENST00000254627.3
Otoconin-90
otoconin 90
chr1_-_108231101 0.62 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr3_+_57882061 0.61 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr2_-_192711968 0.61 ENST00000304141.4
serum deprivation response
chr17_+_6658878 0.61 ENST00000574394.1
XIAP associated factor 1
chr7_+_7811992 0.60 ENST00000406829.1
RPA3 antisense RNA 1
chr8_+_85095497 0.59 ENST00000522455.1
ENST00000521695.1
RALY RNA binding protein-like
chr14_-_55878538 0.59 ENST00000247178.5
autophagy related 14
chr8_+_24151553 0.59 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr16_-_69390209 0.59 ENST00000563634.1
Uncharacterized protein
chr7_+_29519486 0.58 ENST00000409041.4
chimerin 2
chr2_+_86947296 0.58 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr9_-_23826298 0.57 ENST00000380117.1
ELAV like neuron-specific RNA binding protein 2
chr2_+_191273052 0.57 ENST00000417958.1
ENST00000432036.1
ENST00000392328.1
major facilitator superfamily domain containing 6
chr14_+_58894404 0.57 ENST00000554463.1
ENST00000555833.1
KIAA0586
chr6_-_42418999 0.56 ENST00000340840.2
ENST00000354325.2
transcriptional regulating factor 1
chr14_+_22988947 0.56 ENST00000390513.1
T cell receptor alpha joining 24
chr12_+_42725554 0.56 ENST00000546750.1
ENST00000547847.1
periphilin 1
chr20_-_43150601 0.55 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr8_-_116673894 0.55 ENST00000395713.2
trichorhinophalangeal syndrome I
chr16_-_68482440 0.55 ENST00000219334.5
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.7 7.0 GO:0097338 response to clozapine(GO:0097338)
0.5 1.6 GO:1904346 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.5 5.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 2.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.5 1.9 GO:0032252 secretory granule localization(GO:0032252)
0.5 7.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 2.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 10.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.4 1.4 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.3 2.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 2.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 2.4 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 0.9 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 2.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 1.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 1.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 1.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.9 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 1.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.9 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 1.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 0.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.5 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 0.5 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.2 0.5 GO:0042245 RNA repair(GO:0042245)
0.2 4.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.5 GO:0003162 atrioventricular node development(GO:0003162) cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.1 1.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.9 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 6.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 2.7 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.4 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 1.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.6 GO:0009597 detection of virus(GO:0009597)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.8 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.0 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 2.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.4 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.4 GO:1901631 postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 1.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.9 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.4 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 8.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 1.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.7 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 2.4 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.6 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.9 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 1.3 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.6 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 1.0 GO:0007420 brain development(GO:0007420)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.6 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.2 GO:0008037 cell recognition(GO:0008037)
0.0 0.6 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.3 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 7.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 10.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.2 1.1 GO:0031673 H zone(GO:0031673)
0.1 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 6.7 GO:0030673 axolemma(GO:0030673)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 2.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 2.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0072487 MSL complex(GO:0072487)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 7.7 GO:0043209 myelin sheath(GO:0043209)
0.0 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.1 GO:0044304 main axon(GO:0044304)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.6 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.3 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0031768 ghrelin receptor binding(GO:0031768)
0.5 1.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.4 7.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 1.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 2.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.3 7.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 3.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 0.8 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 1.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 4.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.5 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 2.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 6.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 4.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 10.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 2.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 8.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 2.9 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0051020 GTPase binding(GO:0051020)
0.0 1.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 2.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 3.5 GO:0005496 steroid binding(GO:0005496)
0.0 6.4 GO:0008017 microtubule binding(GO:0008017)
0.0 1.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.7 PID ATR PATHWAY ATR signaling pathway
0.1 8.2 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 8.2 PID FGF PATHWAY FGF signaling pathway
0.1 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.8 PID FOXO PATHWAY FoxO family signaling
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 1.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 7.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 7.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 1.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.2 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 3.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell