ISMARA results: STAT1_STAT3

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Illumina Body Map 2, young vs old

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Results for STAT1_STAT3_BCL6

Z-value: 0.10

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol	Gene ID	Gene Info
STAT1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000115415.14	signal transducer and activator of transcription 1
STAT3 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000168610.10	signal transducer and activator of transcription 3
BCL6 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000113916.13	BCL6 transcription repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
STAT1	hg19_v2_chr2_-_191878162_191878313	-0.50	3.2e-03	Click!
STAT3	hg19_v2_chr17_-_40540586_40540600	0.32	7.4e-02	Click!
BCL6	hg19_v2_chr3_-_187455680_187455732	-0.28	1.3e-01	Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_230850043 Show fit	8.64	ENST00000366667.4	AGT Ensembl NCBI GeneCards UniProt NextProt Show fit	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_-_93692681 Show fit	6.77	ENST00000348974.4	PROS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein S (alpha)
chr17_+_77021702 Show fit	6.62	ENST00000392445.2 ENST00000354124.3	C1QTNF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	C1q and tumor necrosis factor related protein 1
chr3_-_93692781 Show fit	6.42	ENST00000394236.3	PROS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein S (alpha)
chr17_+_32683456 Show fit	5.83	ENST00000225844.2	CCL13 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) ligand 13
chr9_-_117880477 Show fit	5.49	ENST00000534839.1 ENST00000340094.3 ENST00000535648.1 ENST00000346706.3 ENST00000345230.3 ENST00000350763.4	TNC Ensembl NCBI GeneCards UniProt NextProt Show fit	tenascin C
chr1_-_68299130 Show fit	5.32	ENST00000370982.3	GNG12 Ensembl NCBI GeneCards UniProt NextProt Show fit	guanine nucleotide binding protein (G protein), gamma 12
chr12_+_53443963 Show fit	5.23	ENST00000546602.1 ENST00000552570.1 ENST00000549700.1	TENC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_148939598 Show fit	5.20	ENST00000455472.3	CP Ensembl NCBI GeneCards UniProt NextProt Show fit	ceruloplasmin (ferroxidase)
chr12_+_53443680 Show fit	4.91	ENST00000314250.6 ENST00000451358.1	TENC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tensin like C1 domain containing phosphatase (tensin 2)
chr12_-_7244469 Show fit	4.67	ENST00000538050.1 ENST00000536053.2	C1R Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, r subcomponent
chr3_-_52864680 Show fit	4.65	ENST00000406595.1 ENST00000485816.1 ENST00000434759.3 ENST00000346281.5 ENST00000266041.4	ITIH4 Ensembl NCBI GeneCards UniProt NextProt Show fit	inter-alpha-trypsin inhibitor heavy chain family, member 4
chr17_-_76356148 Show fit	4.62	ENST00000587578.1 ENST00000330871.2	SOCS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 3
chrX_-_139866723 Show fit	4.36	ENST00000370532.2	CDR1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cerebellar degeneration-related protein 1, 34kDa
chr20_-_49308048 Show fit	4.22	ENST00000327979.2	FAM65C Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 65, member C
chr15_+_84322827 Show fit	4.10	ENST00000286744.5 ENST00000567476.1	ADAMTSL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADAMTS-like 3
chr12_-_7245018 Show fit	4.04	ENST00000543835.1 ENST00000535233.2	C1R Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, r subcomponent
chr1_+_207262578 Show fit	4.04	ENST00000243611.5 ENST00000367076.3	C4BPB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4 binding protein, beta
chr5_+_40909354 Show fit	3.96	ENST00000313164.9	C7 Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 7
chr3_-_148939835 Show fit	3.96	ENST00000264613.6	CP Ensembl NCBI GeneCards UniProt NextProt Show fit	ceruloplasmin (ferroxidase)
chr19_+_35773242 Show fit	3.67	ENST00000222304.3	HAMP Ensembl NCBI GeneCards UniProt NextProt Show fit	hepcidin antimicrobial peptide
chr17_-_26697304 Show fit	3.62	ENST00000536498.1	VTN Ensembl NCBI GeneCards UniProt NextProt Show fit	vitronectin
chr4_-_185820602 Show fit	3.58	ENST00000515864.1 ENST00000507183.1	RP11-701P16.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	long intergenic non-protein coding RNA 1093
chr4_-_155511887 Show fit	3.36	ENST00000302053.3 ENST00000403106.3	FGA Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen alpha chain
chr19_+_15218180 Show fit	3.32	ENST00000342784.2 ENST00000597977.1 ENST00000600440.1	SYDE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_+_76493294 Show fit	3.18	ENST00000533752.1	TSKU Ensembl NCBI GeneCards UniProt NextProt Show fit	tsukushi, small leucine rich proteoglycan
chr16_+_72088376 Show fit	3.16	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP Ensembl NCBI GeneCards UniProt NextProt Show fit HPR Ensembl NCBI GeneCards UniProt NextProt Show fit	haptoglobin haptoglobin-related protein
chr17_+_32582293 Show fit	3.15	ENST00000580907.1 ENST00000225831.4	CCL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) ligand 2
chr1_+_207262540 Show fit	3.15	ENST00000452902.2	C4BPB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4 binding protein, beta
chr3_-_149095652 Show fit	3.04	ENST00000305366.3	TM4SF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane 4 L six family member 1
chr16_-_10652993 Show fit	2.99	ENST00000536829.1	EMP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	epithelial membrane protein 2
chr20_-_49307897 Show fit	2.95	ENST00000535356.1	FAM65C Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 65, member C
chr9_+_97766409 Show fit	2.94	ENST00000425634.2	C9orf3 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 3
chr7_+_134464414 Show fit	2.75	ENST00000361901.2	CALD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	caldesmon 1
chr14_-_25519095 Show fit	2.67	ENST00000419632.2 ENST00000358326.2 ENST00000396700.1 ENST00000548724.1	STXBP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin binding protein 6 (amisyn)
chr19_-_58864848 Show fit	2.64	ENST00000263100.3	A1BG Ensembl NCBI GeneCards UniProt NextProt Show fit	alpha-1-B glycoprotein
chr8_+_19759228 Show fit	2.63	ENST00000520959.1	LPL Ensembl NCBI GeneCards UniProt NextProt Show fit	lipoprotein lipase
chr1_+_202431859 Show fit	2.62	ENST00000391959.3 ENST00000367270.4	PPP1R12B Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1, regulatory subunit 12B
chr9_-_117853297 Show fit	2.55	ENST00000542877.1 ENST00000537320.1 ENST00000341037.4	TNC Ensembl NCBI GeneCards UniProt NextProt Show fit	tenascin C
chr7_+_134464376 Show fit	2.53	ENST00000454108.1 ENST00000361675.2	CALD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	caldesmon 1
chr1_+_207262627 Show fit	2.52	ENST00000391923.1	C4BPB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4 binding protein, beta
chr1_+_207262170 Show fit	2.51	ENST00000367078.3	C4BPB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4 binding protein, beta
chr2_-_190044480 Show fit	2.41	ENST00000374866.3	COL5A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen, type V, alpha 2
chr3_-_145940126 Show fit	2.37	ENST00000498625.1	PLSCR4 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 4
chr17_+_40912764 Show fit	2.35	ENST00000589683.1 ENST00000588928.1	RAMP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	receptor (G protein-coupled) activity modifying protein 2
chr11_+_57365150 Show fit	2.32	ENST00000457869.1 ENST00000340687.6 ENST00000378323.4 ENST00000378324.2 ENST00000403558.1	SERPING1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr9_+_97766469 Show fit	2.31	ENST00000433691.2	C9orf3 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 9 open reading frame 3
chr22_-_50699701 Show fit	2.30	ENST00000395780.1	MAPK12 Ensembl NCBI GeneCards UniProt NextProt Show fit	mitogen-activated protein kinase 12
chr4_-_155533787 Show fit	2.28	ENST00000407946.1 ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1	FGG Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen gamma chain
chr3_-_145940214 Show fit	2.24	ENST00000481701.1	PLSCR4 Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipid scramblase 4
chrX_-_154563889 Show fit	2.24	ENST00000369449.2 ENST00000321926.4	CLIC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride intracellular channel 2
chr22_+_33197683 Show fit	2.20	ENST00000266085.6	TIMP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	TIMP metallopeptidase inhibitor 3
chr19_-_4717835 Show fit	2.13	ENST00000599248.1	DPP9 Ensembl NCBI GeneCards UniProt NextProt Show fit	dipeptidyl-peptidase 9
chr1_-_153521714 Show fit	2.10	ENST00000368713.3	S100A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A3
chr9_+_70971815 Show fit	2.10	ENST00000396392.1 ENST00000396396.1	PGM5 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoglucomutase 5
chr11_+_57531292 Show fit	2.09	ENST00000524579.1	CTNND1 Ensembl NCBI GeneCards UniProt NextProt Show fit	catenin (cadherin-associated protein), delta 1
chr10_-_33625154 Show fit	2.08	ENST00000265371.4	NRP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuropilin 1
chr7_-_87936195 Show fit	2.06	ENST00000414498.1 ENST00000301959.5 ENST00000380079.4	STEAP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	STEAP family member 4
chr9_+_92316557 Show fit	2.06	ENST00000444374.1	RP11-316P17.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-316P17.2
chr1_-_147245445 Show fit	2.05	ENST00000430508.1	GJA5 Ensembl NCBI GeneCards UniProt NextProt Show fit	gap junction protein, alpha 5, 40kDa
chr11_-_102668879 Show fit	2.05	ENST00000315274.6	MMP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_93964746 Show fit	1.95	ENST00000536696.2	SOCS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	suppressor of cytokine signaling 2
chr11_+_46740730 Show fit	1.91	ENST00000311907.5 ENST00000530231.1 ENST00000442468.1	F2 Ensembl NCBI GeneCards UniProt NextProt Show fit	coagulation factor II (thrombin)
chr5_-_42812143 Show fit	1.89	ENST00000514985.1	SEPP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	selenoprotein P, plasma, 1
chr1_-_147245484 Show fit	1.88	ENST00000271348.2	GJA5 Ensembl NCBI GeneCards UniProt NextProt Show fit	gap junction protein, alpha 5, 40kDa
chr5_-_146781153 Show fit	1.87	ENST00000520473.1	DPYSL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydropyrimidinase-like 3
chr1_+_22979474 Show fit	1.87	ENST00000509305.1	C1QB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, q subcomponent, B chain
chr11_+_7506837 Show fit	1.87	ENST00000528758.1	OLFML1 Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactomedin-like 1
chr12_-_21928515 Show fit	1.85	ENST00000537950.1	KCNJ8 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium inwardly-rectifying channel, subfamily J, member 8
chr12_-_91539918 Show fit	1.82	ENST00000548218.1	DCN Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr10_-_90751038 Show fit	1.81	ENST00000458159.1 ENST00000415557.1 ENST00000458208.1	ACTA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	actin, alpha 2, smooth muscle, aorta
chr2_-_128399706 Show fit	1.78	ENST00000426981.1	LIMS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	LIM and senescent cell antigen-like domains 2
chr1_+_155099927 Show fit	1.78	ENST00000368407.3	EFNA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ephrin-A1
chr1_+_22979676 Show fit	1.75	ENST00000432749.2 ENST00000314933.6	C1QB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, q subcomponent, B chain
chr14_-_94919103 Show fit	1.74	ENST00000334708.3	SERPINA11 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr14_-_21270995 Show fit	1.69	ENST00000555698.1 ENST00000397970.4 ENST00000340900.3	RNASE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease, RNase A family, 1 (pancreatic)
chr1_+_56880606 Show fit	1.67	ENST00000451914.1	RP4-710M16.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP4-710M16.2
chrX_-_10544942 Show fit	1.63	ENST00000380779.1	MID1 Ensembl NCBI GeneCards UniProt NextProt Show fit	midline 1 (Opitz/BBB syndrome)
chr4_-_110723134 Show fit	1.61	ENST00000510800.1 ENST00000512148.1	CFI Ensembl NCBI GeneCards UniProt NextProt Show fit	complement factor I
chr5_-_122372354 Show fit	1.61	ENST00000306442.4	PPIC Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidylprolyl isomerase C (cyclophilin C)
chr8_-_86253888 Show fit	1.59	ENST00000522389.1 ENST00000432364.2 ENST00000517618.1	CA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	carbonic anhydrase I
chr6_-_46889694 Show fit	1.59	ENST00000283296.7 ENST00000362015.4 ENST00000456426.2	GPR116 Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein-coupled receptor 116
chr4_-_110723335 Show fit	1.58	ENST00000394634.2	CFI Ensembl NCBI GeneCards UniProt NextProt Show fit	complement factor I
chr8_-_120651020 Show fit	1.57	ENST00000522826.1 ENST00000520066.1 ENST00000259486.6 ENST00000075322.6	ENPP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_214163033 Show fit	1.56	ENST00000607425.1	PROX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	prospero homeobox 1
chr4_-_110723194 Show fit	1.54	ENST00000394635.3	CFI Ensembl NCBI GeneCards UniProt NextProt Show fit	complement factor I
chr22_-_31503490 Show fit	1.53	ENST00000400299.2	SELM Ensembl NCBI GeneCards UniProt NextProt Show fit	Selenoprotein M
chr7_+_117120017 Show fit	1.53	ENST00000003084.6 ENST00000454343.1	CFTR Ensembl NCBI GeneCards UniProt NextProt Show fit	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_-_11107280 Show fit	1.51	ENST00000400897.3 ENST00000400898.3	MASP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	mannan-binding lectin serine peptidase 2
chr8_-_82395461 Show fit	1.51	ENST00000256104.4	FABP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 4, adipocyte
chr5_+_38845960 Show fit	1.51	ENST00000502536.1	OSMR Ensembl NCBI GeneCards UniProt NextProt Show fit	oncostatin M receptor
chr2_-_105030466 Show fit	1.49	ENST00000449772.1	AC068535.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC068535.3
chr3_-_112329110 Show fit	1.47	ENST00000479368.1	CCDC80 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 80
chr9_-_89562104 Show fit	1.47	ENST00000298743.7	GAS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	growth arrest-specific 1
chr8_+_30300119 Show fit	1.47	ENST00000520191.1	RBPMS Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein with multiple splicing
chr1_-_144994909 Show fit	1.47	ENST00000369347.4 ENST00000369354.3	PDE4DIP Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 4D interacting protein
chr19_+_10381769 Show fit	1.47	ENST00000423829.2 ENST00000588645.1	ICAM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	intercellular adhesion molecule 1
chr5_+_140501581 Show fit	1.46	ENST00000194152.1	PCDHB4 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin beta 4
chr14_-_21270561 Show fit	1.46	ENST00000412779.2	RNASE1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease, RNase A family, 1 (pancreatic)
chr1_-_144995074 Show fit	1.46	ENST00000534536.1	PDE4DIP Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 4D interacting protein
chr9_+_133231604 Show fit	1.46	ENST00000442930.1	HMCN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	hemicentin 2
chr18_+_21464737 Show fit	1.42	ENST00000586751.1	LAMA3 Ensembl NCBI GeneCards UniProt NextProt Show fit	laminin, alpha 3
chr1_-_112903150 Show fit	1.41	ENST00000427290.1	RP5-965F6.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP5-965F6.2
chr12_-_22063787 Show fit	1.40	ENST00000544039.1	ABCC9 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr8_+_19796381 Show fit	1.38	ENST00000524029.1 ENST00000522701.1 ENST00000311322.8	LPL Ensembl NCBI GeneCards UniProt NextProt Show fit	lipoprotein lipase
chr12_-_88974236 Show fit	1.38	ENST00000228280.5 ENST00000552044.1 ENST00000357116.4	KITLG Ensembl NCBI GeneCards UniProt NextProt Show fit	KIT ligand
chr5_-_145214893 Show fit	1.38	ENST00000394450.2	PRELID2 Ensembl NCBI GeneCards UniProt NextProt Show fit	PRELI domain containing 2
chr1_-_153521597 Show fit	1.37	ENST00000368712.1	S100A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A3
chr5_+_38846101 Show fit	1.36	ENST00000274276.3	OSMR Ensembl NCBI GeneCards UniProt NextProt Show fit	oncostatin M receptor
chr14_-_25479811 Show fit	1.36	ENST00000550887.1	STXBP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	syntaxin binding protein 6 (amisyn)
chr2_+_169659121 Show fit	1.34	ENST00000397206.2 ENST00000397209.2 ENST00000421711.2	NOSTRIN Ensembl NCBI GeneCards UniProt NextProt Show fit	nitric oxide synthase trafficking
chrX_+_138612889 Show fit	1.34	ENST00000218099.2 ENST00000394090.2	F9 Ensembl NCBI GeneCards UniProt NextProt Show fit	coagulation factor IX
chr14_-_30396948 Show fit	1.31	ENST00000331968.5	PRKD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase D1
chr4_+_166300084 Show fit	1.30	ENST00000402744.4	CPE Ensembl NCBI GeneCards UniProt NextProt Show fit	carboxypeptidase E
chr2_+_97203082 Show fit	1.27	ENST00000454558.2	ARID5A Ensembl NCBI GeneCards UniProt NextProt Show fit	AT rich interactive domain 5A (MRF1-like)
chr11_+_112041253 Show fit	1.26	ENST00000532612.1	AP002884.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	AP002884.3
chr2_+_169658928 Show fit	1.26	ENST00000317647.7 ENST00000445023.2	NOSTRIN Ensembl NCBI GeneCards UniProt NextProt Show fit	nitric oxide synthase trafficking
chr5_+_140625147 Show fit	1.24	ENST00000231173.3	PCDHB15 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin beta 15
chr5_-_38845812 Show fit	1.21	ENST00000513480.1 ENST00000512519.1	CTD-2127H9.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD-2127H9.1
chr4_-_76957214 Show fit	1.21	ENST00000306621.3	CXCL11 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-X-C motif) ligand 11
chr14_+_76452090 Show fit	1.19	ENST00000314067.6 ENST00000238628.6 ENST00000556742.1	IFT43 Ensembl NCBI GeneCards UniProt NextProt Show fit	intraflagellar transport 43 homolog (Chlamydomonas)
chr7_-_75443118 Show fit	1.19	ENST00000222902.2	CCL24 Ensembl NCBI GeneCards UniProt NextProt Show fit	chemokine (C-C motif) ligand 24
chr22_+_23054174 Show fit	1.18	ENST00000390308.2	IGLV3-21 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin lambda variable 3-21
chr7_+_117120106 Show fit	1.17	ENST00000426809.1	CFTR Ensembl NCBI GeneCards UniProt NextProt Show fit	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr14_+_94577074 Show fit	1.17	ENST00000444961.1 ENST00000448882.1 ENST00000557098.1 ENST00000554800.1 ENST00000556544.1 ENST00000298902.5 ENST00000555819.1 ENST00000557634.1 ENST00000555744.1	IFI27 Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon, alpha-inducible protein 27
chr1_-_203198790 Show fit	1.17	ENST00000367229.1 ENST00000255427.3 ENST00000535569.1	CHIT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	chitinase 1 (chitotriosidase)
chr1_+_32712815 Show fit	1.15	ENST00000373582.3	FAM167B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 167, member B
chr17_-_41132088 Show fit	1.15	ENST00000591916.1 ENST00000451885.2 ENST00000454303.1	PTGES3L Ensembl NCBI GeneCards UniProt NextProt Show fit PTGES3L-AARSD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	prostaglandin E synthase 3 (cytosolic)-like PTGES3L-AARSD1 readthrough
chr19_-_4540486 Show fit	1.13	ENST00000306390.6	LRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine-rich alpha-2-glycoprotein 1
chr12_-_291556 Show fit	1.12	ENST00000537295.1 ENST00000537961.1	RP11-598F7.6 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-598F7.6
chr14_-_107083690 Show fit	1.11	ENST00000455737.1 ENST00000390629.2	IGHV4-59 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin heavy variable 4-59
chr8_-_6420565 Show fit	1.09	ENST00000338312.6	ANGPT2 Ensembl NCBI GeneCards UniProt NextProt Show fit	angiopoietin 2
chr3_-_151176497 Show fit	1.08	ENST00000282466.3	IGSF10 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily, member 10
chr1_+_163039143 Show fit	1.07	ENST00000531057.1 ENST00000527809.1 ENST00000367908.4	RGS4 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of G-protein signaling 4
chr19_-_7812446 Show fit	1.07	ENST00000394173.4 ENST00000301357.8	CD209 Ensembl NCBI GeneCards UniProt NextProt Show fit	CD209 molecule
chr14_-_92414294 Show fit	1.06	ENST00000554468.1	FBLN5 Ensembl NCBI GeneCards UniProt NextProt Show fit	fibulin 5
chr19_-_11688951 Show fit	1.05	ENST00000589792.1	ACP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	acid phosphatase 5, tartrate resistant
chr11_+_111412271 Show fit	1.05	ENST00000528102.1	LAYN Ensembl NCBI GeneCards UniProt NextProt Show fit	layilin
chr6_+_97010424 Show fit	1.05	ENST00000541107.1 ENST00000450218.1 ENST00000326771.2	FHL5 Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 5
chr17_-_19265982 Show fit	1.04	ENST00000268841.6 ENST00000261499.4 ENST00000575478.1	B9D1 Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 protein domain 1
chr10_-_35104185 Show fit	1.04	ENST00000374789.3 ENST00000374788.3 ENST00000346874.4 ENST00000374794.3 ENST00000350537.4 ENST00000374790.3 ENST00000374776.1 ENST00000374773.1 ENST00000545693.1 ENST00000545260.1 ENST00000340077.5	PARD3 Ensembl NCBI GeneCards UniProt NextProt Show fit	par-3 family cell polarity regulator
chr8_-_6420777 Show fit	1.03	ENST00000415216.1	ANGPT2 Ensembl NCBI GeneCards UniProt NextProt Show fit	angiopoietin 2
chr2_-_106013400 Show fit	1.02	ENST00000409807.1	FHL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	four and a half LIM domains 2
chr2_-_204398141 Show fit	1.00	ENST00000428637.1	RAPH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_-_201368653 Show fit	1.00	ENST00000367313.3	LAD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ladinin 1
chr3_-_112356944 Show fit	1.00	ENST00000461431.1	CCDC80 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 80
chr8_-_6420930 Show fit	0.99	ENST00000325203.5	ANGPT2 Ensembl NCBI GeneCards UniProt NextProt Show fit	angiopoietin 2
chr1_-_144994840 Show fit	0.98	ENST00000369351.3 ENST00000369349.3	PDE4DIP Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 4D interacting protein
chr11_+_130318869 Show fit	0.97	ENST00000299164.2	ADAMTS15 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr16_+_30996502 Show fit	0.97	ENST00000353250.5 ENST00000262520.6 ENST00000297679.5 ENST00000562932.1 ENST00000574447.1	HSD3B7 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_-_94759361 Show fit	0.95	ENST00000393096.1	SERPINA10 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr6_+_44194762 Show fit	0.94	ENST00000371708.1	SLC29A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_7261772 Show fit	0.94	ENST00000545280.1 ENST00000543933.1 ENST00000545337.1 ENST00000544702.1 ENST00000266542.4	C1RL Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 1, r subcomponent-like
chr14_-_94759408 Show fit	0.94	ENST00000554723.1	SERPINA10 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_162602244 Show fit	0.94	ENST00000367922.3 ENST00000367921.3	DDR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	discoidin domain receptor tyrosine kinase 2
chr11_+_111782934 Show fit	0.94	ENST00000304298.3	HSPB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_-_2162468 Show fit	0.94	ENST00000434045.2	IGF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 (somatomedin A)
chr4_+_126237554 Show fit	0.94	ENST00000394329.3	FAT4 Ensembl NCBI GeneCards UniProt NextProt Show fit	FAT atypical cadherin 4
chr4_+_155484103 Show fit	0.93	ENST00000302068.4	FGB Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen beta chain
chr14_+_100240019 Show fit	0.93	ENST00000556199.1	EML1 Ensembl NCBI GeneCards UniProt NextProt Show fit	echinoderm microtubule associated protein like 1
chr11_-_6462210 Show fit	0.92	ENST00000265983.3	HPX Ensembl NCBI GeneCards UniProt NextProt Show fit	hemopexin
chr17_-_9694614 Show fit	0.91	ENST00000330255.5 ENST00000571134.1	DHRS7C Ensembl NCBI GeneCards UniProt NextProt Show fit	dehydrogenase/reductase (SDR family) member 7C
chr15_+_74466012 Show fit	0.91	ENST00000249842.3	ISLR Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin superfamily containing leucine-rich repeat
chr14_-_24977457 Show fit	0.91	ENST00000250378.3 ENST00000206446.4	CMA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	chymase 1, mast cell
chr1_+_1370903 Show fit	0.90	ENST00000338660.5 ENST00000404702.3 ENST00000476993.1 ENST00000471398.1	VWA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	von Willebrand factor A domain containing 1
chr14_-_94759595 Show fit	0.90	ENST00000261994.4	SERPINA10 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_155484155 Show fit	0.90	ENST00000509493.1	FGB Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen beta chain
chr1_-_201368707 Show fit	0.90	ENST00000391967.2	LAD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ladinin 1
chr1_-_154946825 Show fit	0.90	ENST00000368453.4 ENST00000368450.1 ENST00000366442.2	SHC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	SHC (Src homology 2 domain containing) transforming protein 1
chr6_-_110011718 Show fit	0.90	ENST00000532976.1	AK9 Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate kinase 9
chr5_-_140013275 Show fit	0.89	ENST00000512545.1 ENST00000302014.6 ENST00000401743.2	CD14 Ensembl NCBI GeneCards UniProt NextProt Show fit	CD14 molecule
chr22_+_38597889 Show fit	0.89	ENST00000338483.2 ENST00000538320.1 ENST00000538999.1 ENST00000441709.1	MAFF Ensembl NCBI GeneCards UniProt NextProt Show fit	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr14_-_106406090 Show fit	0.89	ENST00000390593.2	IGHV6-1 Ensembl NCBI GeneCards UniProt NextProt Show fit	immunoglobulin heavy variable 6-1
chr17_-_19265855 Show fit	0.89	ENST00000440841.1 ENST00000395615.1 ENST00000461069.2	B9D1 Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 protein domain 1
chr3_+_45067659 Show fit	0.89	ENST00000296130.4	CLEC3B Ensembl NCBI GeneCards UniProt NextProt Show fit	C-type lectin domain family 3, member B
chr1_+_16083154 Show fit	0.88	ENST00000375771.1	FBLIM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	filamin binding LIM protein 1
chr2_+_173686303 Show fit	0.88	ENST00000397087.3	RAPGEF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_112930946 Show fit	0.88	ENST00000462425.1	BOC Ensembl NCBI GeneCards UniProt NextProt Show fit	BOC cell adhesion associated, oncogene regulated
chr10_-_48416849 Show fit	0.87	ENST00000249598.1	GDF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	growth differentiation factor 2
chr19_-_49339732 Show fit	0.86	ENST00000599157.1	HSD17B14 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (17-beta) dehydrogenase 14
chr22_-_36357671 Show fit	0.86	ENST00000408983.2	RBFOX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_49339915 Show fit	0.86	ENST00000263278.4	HSD17B14 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid (17-beta) dehydrogenase 14
chr7_-_74267836 Show fit	0.86	ENST00000361071.5 ENST00000453619.2 ENST00000417115.2 ENST00000405086.2	GTF2IRD2 Ensembl NCBI GeneCards UniProt NextProt Show fit	GTF2I repeat domain containing 2
chr6_+_125540951 Show fit	0.85	ENST00000524679.1	TPD52L1 Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor protein D52-like 1
chr1_-_144995002 Show fit	0.85	ENST00000369356.4	PDE4DIP Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 4D interacting protein
chr4_+_55096010 Show fit	0.85	ENST00000503856.1	PDGFRA Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet-derived growth factor receptor, alpha polypeptide
chr1_+_16083098 Show fit	0.85	ENST00000496928.2 ENST00000508310.1	FBLIM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	filamin binding LIM protein 1
chr11_-_2162162 Show fit	0.84	ENST00000381389.1	IGF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor 2 (somatomedin A)
chr17_-_73505961 Show fit	0.84	ENST00000433559.2	CASKIN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	CASK interacting protein 2
chr11_-_111782484 Show fit	0.84	ENST00000533971.1	CRYAB Ensembl NCBI GeneCards UniProt NextProt Show fit	crystallin, alpha B
chr1_+_207262881 Show fit	0.83	ENST00000451804.2	C4BPB Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 4 binding protein, beta
chr1_-_31845914 Show fit	0.83	ENST00000373713.2	FABP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr1_+_26485511 Show fit	0.83	ENST00000374268.3	FAM110D Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 110, member D
chr14_-_76447336 Show fit	0.83	ENST00000556285.1	TGFB3 Ensembl NCBI GeneCards UniProt NextProt Show fit	transforming growth factor, beta 3
chr22_+_38609538 Show fit	0.82	ENST00000407965.1	MAFF Ensembl NCBI GeneCards UniProt NextProt Show fit	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr17_+_76356516 Show fit	0.82	ENST00000592569.1	RP11-806H10.4 Ensembl NCBI GeneCards UniProt NextProt Show fit	RP11-806H10.4
chrX_-_65253506 Show fit	0.82	ENST00000427538.1	VSIG4 Ensembl NCBI GeneCards UniProt NextProt Show fit	V-set and immunoglobulin domain containing 4
chr5_+_140723601 Show fit	0.81	ENST00000253812.6	PCDHGA3 Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin gamma subfamily A, 3
chr11_-_115127611 Show fit	0.81	ENST00000545094.1	CADM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	cell adhesion molecule 1
chr3_+_136537911 Show fit	0.81	ENST00000393079.3	SLC35G2 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 35, member G2

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	8.6	GO:0034226	lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
1.9	5.8	GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
1.6	8.0	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
1.3	3.9	GO:0098906	atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
1.3	13.0	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
1.2	3.7	GO:1990641	cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
1.1	3.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.1	3.2	GO:2000502	negative regulation of natural killer cell chemotaxis(GO:2000502)
0.9	3.7	GO:0050928	negative regulation of positive chemotaxis(GO:0050928)
0.9	4.6	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.9	16.4	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8	3.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.8	6.6	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.8	2.4	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.8	3.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.8	2.3	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7	2.7	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.6	2.2	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.5	1.6	GO:0006756	dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.5	1.6	GO:0042704	detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.5	1.6	GO:0061114	hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5	0.9	GO:0090264	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.5	1.4	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4	4.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.4	2.1	GO:1902378	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4	2.8	GO:0008218	bioluminescence(GO:0008218)
0.4	2.0	GO:0030070	insulin processing(GO:0030070)
0.4	5.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.4	2.9	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.3	11.5	GO:0006825	copper ion transport(GO:0006825)
0.3	1.8	GO:0090131	mesenchyme migration(GO:0090131)
0.3	0.9	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.3	0.9	GO:0046041	ITP metabolic process(GO:0046041)
0.3	2.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	1.8	GO:0071727	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3	4.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.3	1.8	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2	3.0	GO:0070836	caveola assembly(GO:0070836)
0.2	2.5	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	1.5	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.2	0.7	GO:0034553	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2	5.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.2	1.7	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2	0.7	GO:0031247	actin rod assembly(GO:0031247)
0.2	0.7	GO:2000910	negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.2	0.9	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.2	1.1	GO:0046968	peptide antigen transport(GO:0046968)
0.2	0.8	GO:0052026	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2	0.4	GO:0007412	axon target recognition(GO:0007412)
0.2	1.6	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.2	1.8	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2	1.2	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.2	3.6	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.4	GO:0051710	regulation of cytolysis in other organism(GO:0051710)
0.2	0.9	GO:0015862	uridine transport(GO:0015862)
0.2	0.9	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.2	0.6	GO:0032824	negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2	4.6	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	2.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	2.9	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	0.7	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	0.5	GO:1990697	protein depalmitoleylation(GO:1990697)
0.2	1.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.2	0.8	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2	2.0	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1	22.5	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	1.3	GO:1901727	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) positive regulation of histone deacetylase activity(GO:1901727)
0.1	1.3	GO:0055011	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1	2.9	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	0.8	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.8	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1	1.7	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	0.5	GO:0071506	response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1	0.9	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.1	0.5	GO:0046035	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	0.5	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	1.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.7	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1	2.3	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.4	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.6	GO:0033384	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1	2.2	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1	1.2	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.1	2.1	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.1	GO:1902824	positive regulation of late endosome to lysosome transport(GO:1902824)
0.1	0.9	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.1	0.3	GO:0060545	positive regulation of necroptotic process(GO:0060545)
0.1	0.4	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1	2.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.4	GO:0044211	CTP salvage(GO:0044211)
0.1	0.6	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	1.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.6	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.5	GO:0071285	cellular response to lithium ion(GO:0071285)
0.1	1.2	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
0.1	0.7	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.4	GO:1990535	neuron projection maintenance(GO:1990535)
0.1	0.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.3	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.1	0.9	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.3	GO:1904425	negative regulation of GTP binding(GO:1904425)
0.1	1.3	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.5	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1	1.0	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.4	GO:0003095	pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.1	0.5	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1	0.3	GO:0008355	olfactory learning(GO:0008355)
0.1	2.7	GO:0007567	parturition(GO:0007567)
0.1	0.3	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.1	1.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.5	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1	0.3	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.1	1.5	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.1	1.8	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	1.7	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.5	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.1	1.4	GO:0051775	response to redox state(GO:0051775)
0.1	0.4	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
0.1	5.1	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.1	0.3	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1	1.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.3	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.1	0.8	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.8	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	2.2	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	2.1	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.1	0.3	GO:2000501	regulation of natural killer cell chemotaxis(GO:2000501)
0.1	0.4	GO:1903772	virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.1	1.5	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.4	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.3	GO:0097017	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) renal protein absorption(GO:0097017) regulation of plasma membrane raft polarization(GO:1903906)
0.1	4.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.1	0.4	GO:0035799	ureter maturation(GO:0035799)
0.1	0.2	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.1	0.5	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.5	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	0.3	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1	0.4	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1	1.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.4	GO:0001878	response to yeast(GO:0001878)
0.0	2.0	GO:0051764	actin crosslink formation(GO:0051764)
0.0	0.2	GO:0044376	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.7	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.3	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.0	0.3	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.5	GO:0070779	gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.7	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.3	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.7	GO:0015747	urate transport(GO:0015747)
0.0	0.2	GO:1902616	acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0	0.9	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	1.7	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.2	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	1.0	GO:0008356	asymmetric cell division(GO:0008356)
0.0	2.6	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.0	0.2	GO:0035669	TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0	0.4	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.7	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.7	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	3.7	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.3	GO:0071486	cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0	0.4	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	1.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.6	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	1.9	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	1.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.8	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.5	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.6	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.0	1.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	1.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0046373	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0	0.6	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.4	GO:0006098	pentose-phosphate shunt(GO:0006098)
0.0	0.3	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.1	GO:0071442	regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.8	GO:1900116	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	1.3	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0006740	NADPH regeneration(GO:0006740)
0.0	0.4	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.4	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.1	GO:0098907	protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0	1.8	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	0.3	GO:0061303	keratan sulfate catabolic process(GO:0042340) cornea development in camera-type eye(GO:0061303)
0.0	0.7	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0014839	myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0	0.4	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	3.6	GO:0002576	platelet degranulation(GO:0002576)
0.0	1.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.9	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0	0.1	GO:0048205	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	1.7	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.3	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.3	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.1	GO:0071105	response to interleukin-11(GO:0071105) cellular response to interleukin-11(GO:0071348)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:0090156	cellular sphingolipid homeostasis(GO:0090156)
0.0	0.1	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	1.3	GO:0035987	endodermal cell differentiation(GO:0035987)
0.0	0.4	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.7	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	1.3	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.9	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.8	GO:0046825	regulation of protein export from nucleus(GO:0046825)
0.0	2.7	GO:0006937	regulation of muscle contraction(GO:0006937)
0.0	0.5	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0	0.4	GO:0070200	establishment of protein localization to telomere(GO:0070200)
0.0	0.4	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0043086	negative regulation of catalytic activity(GO:0043086)
0.0	0.6	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.0	0.1	GO:0009149	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0	0.1	GO:1901475	pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0	0.2	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.4	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.4	GO:0045776	negative regulation of blood pressure(GO:0045776)
0.0	0.0	GO:0097198	histone H3-K36 trimethylation(GO:0097198)
0.0	3.3	GO:0006936	muscle contraction(GO:0006936)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0060356	leucine import(GO:0060356)
0.0	0.1	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.0	0.7	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.5	GO:0071526	semaphorin-plexin signaling pathway(GO:0071526)
0.0	0.6	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0051510	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0	2.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	0.0	GO:1904017	cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.2	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.6	GO:0042073	intraciliary transport(GO:0042073)
0.0	0.6	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	1.0	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.3	GO:0043968	histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	5.8	GO:0044299	C-fiber(GO:0044299)
1.0	2.9	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.9	3.6	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.8	2.4	GO:0005588	collagen type V trimer(GO:0005588)
0.8	3.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.7	3.6	GO:0005602	complement component C1 complex(GO:0005602)
0.5	7.5	GO:0005577	fibrinogen complex(GO:0005577)
0.4	2.7	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.4	4.4	GO:0005579	membrane attack complex(GO:0005579)
0.4	7.9	GO:0031089	platelet dense granule lumen(GO:0031089)
0.4	3.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.4	5.6	GO:0030478	actin cap(GO:0030478)
0.4	11.4	GO:0005614	interstitial matrix(GO:0005614)
0.3	2.4	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.3	1.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.2	2.7	GO:0097443	sorting endosome(GO:0097443)
0.2	1.7	GO:0070435	Shc-EGFR complex(GO:0070435)
0.2	1.8	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.2	50.5	GO:0072562	blood microparticle(GO:0072562)
0.2	4.0	GO:0042627	chylomicron(GO:0042627)
0.2	3.3	GO:0045179	apical cortex(GO:0045179)
0.2	1.8	GO:0071953	elastic fiber(GO:0071953)
0.2	2.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	1.1	GO:0036021	endolysosome lumen(GO:0036021)
0.1	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	1.4	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.7	GO:0031673	H zone(GO:0031673)
0.1	1.8	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.8	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.1	14.7	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	2.5	GO:0005915	zonula adherens(GO:0005915)
0.1	2.7	GO:0005922	connexon complex(GO:0005922)
0.1	1.6	GO:0097512	cardiac myofibril(GO:0097512)
0.1	4.0	GO:0000145	exocyst(GO:0000145)
0.1	1.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.4	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	1.6	GO:0032059	bleb(GO:0032059)
0.1	1.7	GO:0036038	MKS complex(GO:0036038)
0.1	5.6	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	1.0	GO:0033269	internode region of axon(GO:0033269)
0.1	3.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	7.4	GO:0005581	collagen trimer(GO:0005581)
0.1	1.1	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	5.0	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	1.0	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	4.3	GO:0031672	A band(GO:0031672)
0.0	2.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.7	GO:0090543	Flemming body(GO:0090543)
0.0	0.3	GO:0008537	proteasome activator complex(GO:0008537)
0.0	1.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.3	GO:0070876	SOSS complex(GO:0070876)
0.0	0.7	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.5	GO:0097433	dense body(GO:0097433)
0.0	0.7	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	1.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.5	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.9	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.7	GO:0051233	spindle midzone(GO:0051233)
0.0	3.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.8	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	1.8	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	1.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.2	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.0	0.1	GO:0031251	PAN complex(GO:0031251)
0.0	1.4	GO:0002102	podosome(GO:0002102)
0.0	0.8	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.6	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.3	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	1.6	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.6	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.9	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0035339	SPOTS complex(GO:0035339)
0.0	2.1	GO:0030175	filopodium(GO:0030175)
0.0	1.5	GO:0005902	microvillus(GO:0005902)
0.0	6.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.0	GO:0000806	Y chromosome(GO:0000806)
0.0	0.3	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	1.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.3	GO:0034707	chloride channel complex(GO:0034707)
0.0	1.5	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.3	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.5	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.2	GO:0033391	chromatoid body(GO:0033391)
0.0	0.6	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.4	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	9.0	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.3	3.9	GO:0086079	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
1.0	4.0	GO:0017129	triglyceride binding(GO:0017129)
0.8	8.0	GO:0045545	syndecan binding(GO:0045545)
0.8	9.5	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7	2.7	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
0.5	3.2	GO:0030492	hemoglobin binding(GO:0030492)
0.5	2.9	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.5	1.9	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.5	3.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.4	0.9	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4	8.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.4	1.7	GO:0005018	platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.4	2.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4	1.6	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.4	1.5	GO:0001855	complement component C4b binding(GO:0001855)
0.4	1.9	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.4	1.4	GO:0008281	sulfonylurea receptor activity(GO:0008281)
0.3	1.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	2.4	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.3	2.4	GO:0097643	amylin receptor activity(GO:0097643)
0.3	2.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3	1.9	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.3	0.8	GO:0070538	oleic acid binding(GO:0070538)
0.3	1.9	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.3	0.8	GO:0042007	interleukin-18 binding(GO:0042007)
0.2	1.7	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	1.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	1.2	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.2	5.3	GO:0042301	phosphate ion binding(GO:0042301)
0.2	1.5	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.2	2.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	1.6	GO:0004064	arylesterase activity(GO:0004064)
0.2	1.9	GO:0008158	hedgehog receptor activity(GO:0008158)
0.2	1.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.2	4.6	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	0.6	GO:0050135	NAD(P)+ nucleosidase activity(GO:0050135)
0.2	0.8	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2	1.7	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.9	GO:0019770	IgG receptor activity(GO:0019770)
0.2	1.0	GO:0004882	androgen receptor activity(GO:0004882)
0.2	0.7	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2	1.6	GO:0050692	DBD domain binding(GO:0050692)
0.2	0.7	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.2	0.5	GO:1990699	palmitoleyl hydrolase activity(GO:1990699)
0.2	1.8	GO:0046790	virion binding(GO:0046790)
0.2	1.6	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.2	5.3	GO:0005523	tropomyosin binding(GO:0005523)
0.2	4.4	GO:0017049	GTP-Rho binding(GO:0017049)
0.2	4.0	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	2.1	GO:0008199	ferric iron binding(GO:0008199)
0.1	4.3	GO:0031005	filamin binding(GO:0031005)
0.1	2.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.4	GO:0019150	D-ribulokinase activity(GO:0019150)
0.1	0.4	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.1	0.6	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.4	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	0.4	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.1	0.5	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.7	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.5	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	1.0	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1	0.6	GO:0004161	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1	2.6	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	0.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	1.7	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1	0.5	GO:0070568	guanylyltransferase activity(GO:0070568)
0.1	1.6	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.3	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1	0.7	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.4	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.9	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.8	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1	0.7	GO:0004447	iodide peroxidase activity(GO:0004447)
0.1	0.5	GO:0003712	transcription cofactor activity(GO:0003712)
0.1	0.5	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	2.5	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.5	GO:0060175	brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1	0.6	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1	0.4	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.1	24.9	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.1	10.2	GO:0005518	collagen binding(GO:0005518)
0.1	4.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.6	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.2	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1	2.7	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.1	1.9	GO:0008527	taste receptor activity(GO:0008527)
0.1	2.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.4	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.4	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1	0.4	GO:0042806	fucose binding(GO:0042806)
0.1	0.6	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.6	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1	0.2	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.1	18.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.2	GO:0030627	pre-mRNA 5'-splice site binding(GO:0030627)
0.1	1.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1	0.9	GO:0015232	heme transporter activity(GO:0015232)
0.1	1.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.9	GO:0004568	chitinase activity(GO:0004568)
0.1	1.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	2.1	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	0.5	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0015227	acyl carnitine transmembrane transporter activity(GO:0015227)
0.0	2.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.7	GO:0031404	chloride ion binding(GO:0031404)
0.0	2.8	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.3	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.3	GO:0045159	myosin II binding(GO:0045159)
0.0	0.7	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.3	GO:0061135	endopeptidase regulator activity(GO:0061135)
0.0	0.1	GO:0008746	NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0	0.3	GO:1990932	5.8S rRNA binding(GO:1990932)
0.0	0.9	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	1.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	1.3	GO:0005521	lamin binding(GO:0005521)
0.0	1.1	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.2	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.0	2.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0005477	pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	4.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.0	0.5	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	1.5	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	1.1	GO:0005504	fatty acid binding(GO:0005504)
0.0	0.3	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	1.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.4	GO:0019826	oxygen sensor activity(GO:0019826)
0.0	0.1	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0	4.3	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	2.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.8	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.3	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.6	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.6	GO:0031402	sodium ion binding(GO:0031402)
0.0	1.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.0	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	0.2	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.5	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.0	1.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0032093	SAM domain binding(GO:0032093)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.5	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.2	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0	0.8	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.9	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	3.2	GO:0030674	protein binding, bridging(GO:0030674)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0039552	RIG-I binding(GO:0039552)
0.0	0.6	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	19.6	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	9.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	13.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	8.0	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	2.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	1.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	3.8	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	4.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	4.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	9.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	2.4	PID ALK1 PATHWAY	ALK1 signaling events
0.1	2.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	1.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	2.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	4.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	21.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	3.0	ST ADRENERGIC	Adrenergic Pathway
0.1	1.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	1.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	2.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	10.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	1.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.8	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	9.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.8	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	1.2	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	1.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	1.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	2.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.5	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.4	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.7	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.9	PID P53 REGULATION PATHWAY	p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	22.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.6	17.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.4	9.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	4.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	5.8	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	8.8	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	5.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.2	3.7	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	9.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	5.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	1.8	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	2.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	3.9	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	14.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	2.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.1	3.3	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	2.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	2.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.4	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	12.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	3.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	1.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	2.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	3.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.3	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	2.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	4.6	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.5	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	1.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	3.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	2.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.9	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	1.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	1.8	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.4	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.3	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	1.1	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.1	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis

Results for STAT1_STAT3_BCL6

Z-value: 0.10

Motif logo

Transcription factors associated with STAT1_STAT3_BCL6

Activity-expression correlation:

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: