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Illumina Body Map 2, young vs old

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Results for STAT1_STAT3_BCL6

Z-value: 0.10

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
ENSG00000115415.14 signal transducer and activator of transcription 1
ENSG00000168610.10 signal transducer and activator of transcription 3
ENSG00000113916.13 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT1hg19_v2_chr2_-_191878162_191878313-0.503.2e-03Click!
STAT3hg19_v2_chr17_-_40540586_405406000.327.4e-02Click!
BCL6hg19_v2_chr3_-_187455680_187455732-0.281.3e-01Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_230850043 8.64 ENST00000366667.4
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_-_93692681 6.77 ENST00000348974.4
protein S (alpha)
chr17_+_77021702 6.62 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr3_-_93692781 6.42 ENST00000394236.3
protein S (alpha)
chr17_+_32683456 5.83 ENST00000225844.2
chemokine (C-C motif) ligand 13
chr9_-_117880477 5.49 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr1_-_68299130 5.32 ENST00000370982.3
guanine nucleotide binding protein (G protein), gamma 12
chr12_+_53443963 5.23 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_148939598 5.20 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr12_+_53443680 4.91 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr12_-_7244469 4.67 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr3_-_52864680 4.65 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr17_-_76356148 4.62 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chrX_-_139866723 4.36 ENST00000370532.2
cerebellar degeneration-related protein 1, 34kDa
chr20_-_49308048 4.22 ENST00000327979.2
family with sequence similarity 65, member C
chr15_+_84322827 4.10 ENST00000286744.5
ENST00000567476.1
ADAMTS-like 3
chr12_-_7245018 4.04 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr1_+_207262578 4.04 ENST00000243611.5
ENST00000367076.3
complement component 4 binding protein, beta
chr5_+_40909354 3.96 ENST00000313164.9
complement component 7
chr3_-_148939835 3.96 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr19_+_35773242 3.67 ENST00000222304.3
hepcidin antimicrobial peptide
chr17_-_26697304 3.62 ENST00000536498.1
vitronectin
chr4_-_185820602 3.58 ENST00000515864.1
ENST00000507183.1
long intergenic non-protein coding RNA 1093
chr4_-_155511887 3.36 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr19_+_15218180 3.32 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr11_+_76493294 3.18 ENST00000533752.1
tsukushi, small leucine rich proteoglycan
chr16_+_72088376 3.16 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr17_+_32582293 3.15 ENST00000580907.1
ENST00000225831.4
chemokine (C-C motif) ligand 2
chr1_+_207262540 3.15 ENST00000452902.2
complement component 4 binding protein, beta
chr3_-_149095652 3.04 ENST00000305366.3
transmembrane 4 L six family member 1
chr16_-_10652993 2.99 ENST00000536829.1
epithelial membrane protein 2
chr20_-_49307897 2.95 ENST00000535356.1
family with sequence similarity 65, member C
chr9_+_97766409 2.94 ENST00000425634.2
chromosome 9 open reading frame 3
chr7_+_134464414 2.75 ENST00000361901.2
caldesmon 1
chr14_-_25519095 2.67 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
syntaxin binding protein 6 (amisyn)
chr19_-_58864848 2.64 ENST00000263100.3
alpha-1-B glycoprotein
chr8_+_19759228 2.63 ENST00000520959.1
lipoprotein lipase
chr1_+_202431859 2.62 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr9_-_117853297 2.55 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr7_+_134464376 2.53 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr1_+_207262627 2.52 ENST00000391923.1
complement component 4 binding protein, beta
chr1_+_207262170 2.51 ENST00000367078.3
complement component 4 binding protein, beta
chr2_-_190044480 2.41 ENST00000374866.3
collagen, type V, alpha 2
chr3_-_145940126 2.37 ENST00000498625.1
phospholipid scramblase 4
chr17_+_40912764 2.35 ENST00000589683.1
ENST00000588928.1
receptor (G protein-coupled) activity modifying protein 2
chr11_+_57365150 2.32 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr9_+_97766469 2.31 ENST00000433691.2
chromosome 9 open reading frame 3
chr22_-_50699701 2.30 ENST00000395780.1
mitogen-activated protein kinase 12
chr4_-_155533787 2.28 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr3_-_145940214 2.24 ENST00000481701.1
phospholipid scramblase 4
chrX_-_154563889 2.24 ENST00000369449.2
ENST00000321926.4
chloride intracellular channel 2
chr22_+_33197683 2.20 ENST00000266085.6
TIMP metallopeptidase inhibitor 3
chr19_-_4717835 2.13 ENST00000599248.1
dipeptidyl-peptidase 9
chr1_-_153521714 2.10 ENST00000368713.3
S100 calcium binding protein A3
chr9_+_70971815 2.10 ENST00000396392.1
ENST00000396396.1
phosphoglucomutase 5
chr11_+_57531292 2.09 ENST00000524579.1
catenin (cadherin-associated protein), delta 1
chr10_-_33625154 2.08 ENST00000265371.4
neuropilin 1
chr7_-_87936195 2.06 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP family member 4
chr9_+_92316557 2.06 ENST00000444374.1
RP11-316P17.2
chr1_-_147245445 2.05 ENST00000430508.1
gap junction protein, alpha 5, 40kDa
chr11_-_102668879 2.05 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_93964746 1.95 ENST00000536696.2
suppressor of cytokine signaling 2
chr11_+_46740730 1.91 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
coagulation factor II (thrombin)
chr5_-_42812143 1.89 ENST00000514985.1
selenoprotein P, plasma, 1
chr1_-_147245484 1.88 ENST00000271348.2
gap junction protein, alpha 5, 40kDa
chr5_-_146781153 1.87 ENST00000520473.1
dihydropyrimidinase-like 3
chr1_+_22979474 1.87 ENST00000509305.1
complement component 1, q subcomponent, B chain
chr11_+_7506837 1.87 ENST00000528758.1
olfactomedin-like 1
chr12_-_21928515 1.85 ENST00000537950.1
potassium inwardly-rectifying channel, subfamily J, member 8
chr12_-_91539918 1.82 ENST00000548218.1
decorin
chr10_-_90751038 1.81 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
actin, alpha 2, smooth muscle, aorta
chr2_-_128399706 1.78 ENST00000426981.1
LIM and senescent cell antigen-like domains 2
chr1_+_155099927 1.78 ENST00000368407.3
ephrin-A1
chr1_+_22979676 1.75 ENST00000432749.2
ENST00000314933.6
complement component 1, q subcomponent, B chain
chr14_-_94919103 1.74 ENST00000334708.3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr14_-_21270995 1.69 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr1_+_56880606 1.67 ENST00000451914.1
RP4-710M16.2
chrX_-_10544942 1.63 ENST00000380779.1
midline 1 (Opitz/BBB syndrome)
chr4_-_110723134 1.61 ENST00000510800.1
ENST00000512148.1
complement factor I
chr5_-_122372354 1.61 ENST00000306442.4
peptidylprolyl isomerase C (cyclophilin C)
chr8_-_86253888 1.59 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
carbonic anhydrase I
chr6_-_46889694 1.59 ENST00000283296.7
ENST00000362015.4
ENST00000456426.2
G protein-coupled receptor 116
chr4_-_110723335 1.58 ENST00000394634.2
complement factor I
chr8_-_120651020 1.57 ENST00000522826.1
ENST00000520066.1
ENST00000259486.6
ENST00000075322.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr1_+_214163033 1.56 ENST00000607425.1
prospero homeobox 1
chr4_-_110723194 1.54 ENST00000394635.3
complement factor I
chr22_-_31503490 1.53 ENST00000400299.2
Selenoprotein M
chr7_+_117120017 1.53 ENST00000003084.6
ENST00000454343.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_-_11107280 1.51 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr8_-_82395461 1.51 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr5_+_38845960 1.51 ENST00000502536.1
oncostatin M receptor
chr2_-_105030466 1.49 ENST00000449772.1
AC068535.3
chr3_-_112329110 1.47 ENST00000479368.1
coiled-coil domain containing 80
chr9_-_89562104 1.47 ENST00000298743.7
growth arrest-specific 1
chr8_+_30300119 1.47 ENST00000520191.1
RNA binding protein with multiple splicing
chr1_-_144994909 1.47 ENST00000369347.4
ENST00000369354.3
phosphodiesterase 4D interacting protein
chr19_+_10381769 1.47 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr5_+_140501581 1.46 ENST00000194152.1
protocadherin beta 4
chr14_-_21270561 1.46 ENST00000412779.2
ribonuclease, RNase A family, 1 (pancreatic)
chr1_-_144995074 1.46 ENST00000534536.1
phosphodiesterase 4D interacting protein
chr9_+_133231604 1.46 ENST00000442930.1
hemicentin 2
chr18_+_21464737 1.42 ENST00000586751.1
laminin, alpha 3
chr1_-_112903150 1.41 ENST00000427290.1
RP5-965F6.2
chr12_-_22063787 1.40 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr8_+_19796381 1.38 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
lipoprotein lipase
chr12_-_88974236 1.38 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KIT ligand
chr5_-_145214893 1.38 ENST00000394450.2
PRELI domain containing 2
chr1_-_153521597 1.37 ENST00000368712.1
S100 calcium binding protein A3
chr5_+_38846101 1.36 ENST00000274276.3
oncostatin M receptor
chr14_-_25479811 1.36 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr2_+_169659121 1.34 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chrX_+_138612889 1.34 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr14_-_30396948 1.31 ENST00000331968.5
protein kinase D1
chr4_+_166300084 1.30 ENST00000402744.4
carboxypeptidase E
chr2_+_97203082 1.27 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr11_+_112041253 1.26 ENST00000532612.1
AP002884.3
chr2_+_169658928 1.26 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr5_+_140625147 1.24 ENST00000231173.3
protocadherin beta 15
chr5_-_38845812 1.21 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr4_-_76957214 1.21 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr14_+_76452090 1.19 ENST00000314067.6
ENST00000238628.6
ENST00000556742.1
intraflagellar transport 43 homolog (Chlamydomonas)
chr7_-_75443118 1.19 ENST00000222902.2
chemokine (C-C motif) ligand 24
chr22_+_23054174 1.18 ENST00000390308.2
immunoglobulin lambda variable 3-21
chr7_+_117120106 1.17 ENST00000426809.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr14_+_94577074 1.17 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr1_-_203198790 1.17 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
chitinase 1 (chitotriosidase)
chr1_+_32712815 1.15 ENST00000373582.3
family with sequence similarity 167, member B
chr17_-_41132088 1.15 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr19_-_4540486 1.13 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr12_-_291556 1.12 ENST00000537295.1
ENST00000537961.1
RP11-598F7.6
chr14_-_107083690 1.11 ENST00000455737.1
ENST00000390629.2
immunoglobulin heavy variable 4-59
chr8_-_6420565 1.09 ENST00000338312.6
angiopoietin 2
chr3_-_151176497 1.08 ENST00000282466.3
immunoglobulin superfamily, member 10
chr1_+_163039143 1.07 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
regulator of G-protein signaling 4
chr19_-_7812446 1.07 ENST00000394173.4
ENST00000301357.8
CD209 molecule
chr14_-_92414294 1.06 ENST00000554468.1
fibulin 5
chr19_-_11688951 1.05 ENST00000589792.1
acid phosphatase 5, tartrate resistant
chr11_+_111412271 1.05 ENST00000528102.1
layilin
chr6_+_97010424 1.05 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
four and a half LIM domains 5
chr17_-_19265982 1.04 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9 protein domain 1
chr10_-_35104185 1.04 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
par-3 family cell polarity regulator
chr8_-_6420777 1.03 ENST00000415216.1
angiopoietin 2
chr2_-_106013400 1.02 ENST00000409807.1
four and a half LIM domains 2
chr2_-_204398141 1.00 ENST00000428637.1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr1_-_201368653 1.00 ENST00000367313.3
ladinin 1
chr3_-_112356944 1.00 ENST00000461431.1
coiled-coil domain containing 80
chr8_-_6420930 0.99 ENST00000325203.5
angiopoietin 2
chr1_-_144994840 0.98 ENST00000369351.3
ENST00000369349.3
phosphodiesterase 4D interacting protein
chr11_+_130318869 0.97 ENST00000299164.2
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr16_+_30996502 0.97 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_-_94759361 0.95 ENST00000393096.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr6_+_44194762 0.94 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_7261772 0.94 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
complement component 1, r subcomponent-like
chr14_-_94759408 0.94 ENST00000554723.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_162602244 0.94 ENST00000367922.3
ENST00000367921.3
discoidin domain receptor tyrosine kinase 2
chr11_+_111782934 0.94 ENST00000304298.3
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_-_2162468 0.94 ENST00000434045.2
insulin-like growth factor 2 (somatomedin A)
chr4_+_126237554 0.94 ENST00000394329.3
FAT atypical cadherin 4
chr4_+_155484103 0.93 ENST00000302068.4
fibrinogen beta chain
chr14_+_100240019 0.93 ENST00000556199.1
echinoderm microtubule associated protein like 1
chr11_-_6462210 0.92 ENST00000265983.3
hemopexin
chr17_-_9694614 0.91 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr15_+_74466012 0.91 ENST00000249842.3
immunoglobulin superfamily containing leucine-rich repeat
chr14_-_24977457 0.91 ENST00000250378.3
ENST00000206446.4
chymase 1, mast cell
chr1_+_1370903 0.90 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
von Willebrand factor A domain containing 1
chr14_-_94759595 0.90 ENST00000261994.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_155484155 0.90 ENST00000509493.1
fibrinogen beta chain
chr1_-_201368707 0.90 ENST00000391967.2
ladinin 1
chr1_-_154946825 0.90 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC (Src homology 2 domain containing) transforming protein 1
chr6_-_110011718 0.90 ENST00000532976.1
adenylate kinase 9
chr5_-_140013275 0.89 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr22_+_38597889 0.89 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr14_-_106406090 0.89 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr17_-_19265855 0.89 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr3_+_45067659 0.89 ENST00000296130.4
C-type lectin domain family 3, member B
chr1_+_16083154 0.88 ENST00000375771.1
filamin binding LIM protein 1
chr2_+_173686303 0.88 ENST00000397087.3
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_112930946 0.88 ENST00000462425.1
BOC cell adhesion associated, oncogene regulated
chr10_-_48416849 0.87 ENST00000249598.1
growth differentiation factor 2
chr19_-_49339732 0.86 ENST00000599157.1
hydroxysteroid (17-beta) dehydrogenase 14
chr22_-_36357671 0.86 ENST00000408983.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_49339915 0.86 ENST00000263278.4
hydroxysteroid (17-beta) dehydrogenase 14
chr7_-_74267836 0.86 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2I repeat domain containing 2
chr6_+_125540951 0.85 ENST00000524679.1
tumor protein D52-like 1
chr1_-_144995002 0.85 ENST00000369356.4
phosphodiesterase 4D interacting protein
chr4_+_55096010 0.85 ENST00000503856.1
platelet-derived growth factor receptor, alpha polypeptide
chr1_+_16083098 0.85 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr11_-_2162162 0.84 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr17_-_73505961 0.84 ENST00000433559.2
CASK interacting protein 2
chr11_-_111782484 0.84 ENST00000533971.1
crystallin, alpha B
chr1_+_207262881 0.83 ENST00000451804.2
complement component 4 binding protein, beta
chr1_-_31845914 0.83 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr1_+_26485511 0.83 ENST00000374268.3
family with sequence similarity 110, member D
chr14_-_76447336 0.83 ENST00000556285.1
transforming growth factor, beta 3
chr22_+_38609538 0.82 ENST00000407965.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr17_+_76356516 0.82 ENST00000592569.1
RP11-806H10.4
chrX_-_65253506 0.82 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr5_+_140723601 0.81 ENST00000253812.6
protocadherin gamma subfamily A, 3
chr11_-_115127611 0.81 ENST00000545094.1
cell adhesion molecule 1
chr3_+_136537911 0.81 ENST00000393079.3
solute carrier family 35, member G2

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
1.9 5.8 GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
1.6 8.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.3 3.9 GO:0098906 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
1.3 13.0 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
1.2 3.7 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
1.1 3.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.1 3.2 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.9 3.7 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.9 4.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 16.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.8 3.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.8 6.6 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.8 2.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 3.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.8 2.3 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7 2.7 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.6 2.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.5 1.6 GO:0006756 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.5 1.6 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.5 1.6 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 0.9 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264)
0.5 1.4 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4 4.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 2.1 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.4 2.8 GO:0008218 bioluminescence(GO:0008218)
0.4 2.0 GO:0030070 insulin processing(GO:0030070)
0.4 5.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 2.9 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 11.5 GO:0006825 copper ion transport(GO:0006825)
0.3 1.8 GO:0090131 mesenchyme migration(GO:0090131)
0.3 0.9 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.3 0.9 GO:0046041 ITP metabolic process(GO:0046041)
0.3 2.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.3 1.8 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 4.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 1.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 3.0 GO:0070836 caveola assembly(GO:0070836)
0.2 2.5 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 0.7 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 5.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.7 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.7 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.2 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.2 1.1 GO:0046968 peptide antigen transport(GO:0046968)
0.2 0.8 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2 0.4 GO:0007412 axon target recognition(GO:0007412)
0.2 1.6 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 1.8 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 1.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 3.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.4 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
0.2 0.9 GO:0015862 uridine transport(GO:0015862)
0.2 0.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.6 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 4.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 2.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 1.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.8 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 2.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 22.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.3 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 2.9 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.8 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.8 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 1.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.5 GO:0071506 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 1.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.7 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 2.3 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 2.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 2.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.3 GO:0060545 positive regulation of necroptotic process(GO:0060545)
0.1 0.4 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 2.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.7 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.3 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.5 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.1 0.5 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.1 2.7 GO:0007567 parturition(GO:0007567)
0.1 0.3 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.1 1.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 1.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 1.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.1 5.1 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 2.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 2.1 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.3 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.4 GO:1903772 virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 1.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.3 GO:0097017 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) renal protein absorption(GO:0097017) regulation of plasma membrane raft polarization(GO:1903906)
0.1 4.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.4 GO:0035799 ureter maturation(GO:0035799)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.5 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.4 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 2.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.5 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.7 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.7 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 1.7 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 1.0 GO:0008356 asymmetric cell division(GO:0008356)
0.0 2.6 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 3.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 1.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.8 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 1.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.4 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 1.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.3 GO:0061303 keratan sulfate catabolic process(GO:0042340) cornea development in camera-type eye(GO:0061303)
0.0 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 3.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.9 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.3 GO:0071236 cellular response to antibiotic(GO:0071236)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105) cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 1.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 1.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.9 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.8 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 2.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.5 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.4 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.0 0.6 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.1 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 3.3 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.0 0.7 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.5 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 2.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.0 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0044299 C-fiber(GO:0044299)
1.0 2.9 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.9 3.6 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.8 2.4 GO:0005588 collagen type V trimer(GO:0005588)
0.8 3.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.7 3.6 GO:0005602 complement component C1 complex(GO:0005602)
0.5 7.5 GO:0005577 fibrinogen complex(GO:0005577)
0.4 2.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.4 4.4 GO:0005579 membrane attack complex(GO:0005579)
0.4 7.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 3.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 5.6 GO:0030478 actin cap(GO:0030478)
0.4 11.4 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.3 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 2.7 GO:0097443 sorting endosome(GO:0097443)
0.2 1.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 1.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 50.5 GO:0072562 blood microparticle(GO:0072562)
0.2 4.0 GO:0042627 chylomicron(GO:0042627)
0.2 3.3 GO:0045179 apical cortex(GO:0045179)
0.2 1.8 GO:0071953 elastic fiber(GO:0071953)
0.2 2.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 1.1 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.4 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 1.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 14.7 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 2.5 GO:0005915 zonula adherens(GO:0005915)
0.1 2.7 GO:0005922 connexon complex(GO:0005922)
0.1 1.6 GO:0097512 cardiac myofibril(GO:0097512)
0.1 4.0 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 1.6 GO:0032059 bleb(GO:0032059)
0.1 1.7 GO:0036038 MKS complex(GO:0036038)
0.1 5.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 3.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 7.4 GO:0005581 collagen trimer(GO:0005581)
0.1 1.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 4.3 GO:0031672 A band(GO:0031672)
0.0 2.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 3.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 2.1 GO:0030175 filopodium(GO:0030175)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 6.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0000806 Y chromosome(GO:0000806)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.3 3.9 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
1.0 4.0 GO:0017129 triglyceride binding(GO:0017129)
0.8 8.0 GO:0045545 syndecan binding(GO:0045545)
0.8 9.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 2.7 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 3.2 GO:0030492 hemoglobin binding(GO:0030492)
0.5 2.9 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.5 1.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.5 3.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 8.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.4 1.7 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.4 2.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 1.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 1.5 GO:0001855 complement component C4b binding(GO:0001855)
0.4 1.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 1.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 2.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 2.4 GO:0097643 amylin receptor activity(GO:0097643)
0.3 2.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 0.8 GO:0070538 oleic acid binding(GO:0070538)
0.3 1.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 0.8 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 1.7 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 5.3 GO:0042301 phosphate ion binding(GO:0042301)
0.2 1.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 2.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.6 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 4.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 0.6 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.2 0.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 1.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.9 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.0 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.6 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.5 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.2 1.8 GO:0046790 virion binding(GO:0046790)
0.2 1.6 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.2 5.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 4.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 4.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 4.3 GO:0031005 filamin binding(GO:0031005)
0.1 2.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.6 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.6 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 2.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.5 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.9 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.5 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 2.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.4 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 24.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 10.2 GO:0005518 collagen binding(GO:0005518)
0.1 4.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 2.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.9 GO:0008527 taste receptor activity(GO:0008527)
0.1 2.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.4 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 18.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 1.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 2.1 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 2.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0061135 endopeptidase regulator activity(GO:0061135)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 2.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 4.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.0 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 3.2 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 19.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 9.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 13.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 8.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.7 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 9.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.4 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 4.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 21.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.0 ST ADRENERGIC Adrenergic Pathway
0.1 1.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 10.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 9.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.2 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 22.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 17.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.4 9.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 5.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 8.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 5.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 3.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 9.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 14.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 3.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 12.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 3.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 2.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 3.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 4.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis