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Illumina Body Map 2, young vs old

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Results for STAT4

Z-value: 0.71

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192015697_192015743-0.048.1e-01Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_196242233 2.35 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr3_+_50649302 1.80 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr4_-_76957214 1.60 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr4_+_169575875 1.49 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr12_-_15082050 1.25 ENST00000540097.1
ERP27
endoplasmic reticulum protein 27
chr6_-_49712123 1.13 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr6_-_123958141 1.01 ENST00000334268.4
TRDN
triadin
chr6_-_49712072 1.00 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr16_-_46782221 0.98 ENST00000394809.4
MYLK3
myosin light chain kinase 3
chr1_+_202431859 0.96 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr6_-_123958051 0.92 ENST00000546248.1
TRDN
triadin
chr6_-_49712091 0.91 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr10_+_115312766 0.87 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr3_-_108672742 0.77 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chr6_-_123957942 0.77 ENST00000398178.3
TRDN
triadin
chr6_-_123958111 0.75 ENST00000542443.1
TRDN
triadin
chr4_-_177162822 0.75 ENST00000512254.1
ASB5
ankyrin repeat and SOCS box containing 5
chr3_-_108672609 0.73 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr9_-_134151915 0.68 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr1_-_120935894 0.66 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr1_+_149754227 0.64 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chrX_+_107288280 0.63 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr1_-_144994909 0.62 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_51875894 0.60 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chrX_+_107288239 0.60 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_107288197 0.60 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr12_-_11139511 0.59 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr1_+_161551101 0.58 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr15_+_63340775 0.57 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr19_+_35225060 0.57 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chrX_-_46187069 0.56 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr14_+_22538811 0.52 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr1_+_161632937 0.51 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr16_-_67517716 0.50 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr5_-_127674883 0.50 ENST00000507835.1
FBN2
fibrillin 2
chr5_-_111092873 0.50 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr4_-_48116540 0.50 ENST00000506073.1
TXK
TXK tyrosine kinase
chr15_+_63340858 0.46 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr14_-_25103472 0.45 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr3_-_156534754 0.44 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr2_+_113885138 0.44 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr12_+_60083118 0.44 ENST00000261187.4
ENST00000543448.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr1_-_144994840 0.44 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_109655377 0.44 ENST00000369948.3
C1orf194
chromosome 1 open reading frame 194
chr8_-_42358742 0.43 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr5_-_111093081 0.43 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr1_-_109655355 0.43 ENST00000369945.3
C1orf194
chromosome 1 open reading frame 194
chr3_-_183735651 0.43 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_100841930 0.43 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS
tryptophanyl-tRNA synthetase
chr14_-_100841670 0.43 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr17_-_42994283 0.41 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr1_-_161337662 0.40 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr5_-_111093340 0.40 ENST00000508870.1
NREP
neuronal regeneration related protein
chr19_-_44405941 0.39 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr19_-_44405623 0.39 ENST00000591815.1
RP11-15A1.3
RP11-15A1.3
chr5_-_111092930 0.39 ENST00000257435.7
NREP
neuronal regeneration related protein
chr11_-_119999611 0.38 ENST00000529044.1
TRIM29
tripartite motif containing 29
chrX_-_70474910 0.38 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_111093167 0.38 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr18_+_61144160 0.38 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr5_-_111093406 0.37 ENST00000379671.3
NREP
neuronal regeneration related protein
chr9_-_85882145 0.37 ENST00000328788.1
FRMD3
FERM domain containing 3
chr2_-_197675000 0.37 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr10_-_116444371 0.36 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr10_+_6625605 0.36 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr2_-_29297127 0.36 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr15_+_63340734 0.35 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr3_+_111260980 0.34 ENST00000438817.2
CD96
CD96 molecule
chr14_+_56127960 0.34 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr5_-_39274617 0.33 ENST00000510188.1
FYB
FYN binding protein
chr11_+_12302492 0.33 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr9_-_116159635 0.32 ENST00000452726.1
ALAD
aminolevulinate dehydratase
chr12_+_14518598 0.31 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
ATF7IP
activating transcription factor 7 interacting protein
chr16_+_78056412 0.31 ENST00000299642.4
ENST00000575655.1
CLEC3A
C-type lectin domain family 3, member A
chr6_+_32407619 0.30 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr5_-_64777733 0.30 ENST00000381055.3
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr5_+_36606700 0.30 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_56716686 0.30 ENST00000520645.1
DST
dystonin
chr11_+_5509915 0.30 ENST00000322641.5
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr11_-_119999539 0.29 ENST00000541857.1
TRIM29
tripartite motif containing 29
chr18_-_67629015 0.29 ENST00000579496.1
CD226
CD226 molecule
chr2_-_160472952 0.29 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr2_+_234294585 0.29 ENST00000447484.1
DGKD
diacylglycerol kinase, delta 130kDa
chr14_-_100841794 0.28 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr6_+_84222220 0.28 ENST00000369700.3
PRSS35
protease, serine, 35
chr1_+_117297007 0.28 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr14_+_56127989 0.28 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr7_-_115670804 0.27 ENST00000320239.7
TFEC
transcription factor EC
chrX_+_149861836 0.27 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr19_+_35225121 0.27 ENST00000595708.1
ENST00000593781.1
ZNF181
zinc finger protein 181
chr20_+_5731027 0.26 ENST00000378979.4
ENST00000303142.6
C20orf196
chromosome 20 open reading frame 196
chr6_+_134210243 0.26 ENST00000367882.4
TCF21
transcription factor 21
chr12_-_11184006 0.26 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chr1_+_17906970 0.26 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_65235916 0.26 ENST00000579861.1
HELZ
helicase with zinc finger
chr3_+_111260954 0.26 ENST00000283285.5
CD96
CD96 molecule
chr18_+_6729725 0.25 ENST00000400091.2
ENST00000583410.1
ENST00000584387.1
ARHGAP28
Rho GTPase activating protein 28
chr6_+_31082603 0.25 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr7_-_115670792 0.25 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr11_+_118175596 0.25 ENST00000528600.1
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr2_+_68962014 0.25 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr12_-_91398796 0.25 ENST00000261172.3
ENST00000551767.1
EPYC
epiphycan
chr5_-_140013224 0.25 ENST00000498971.2
CD14
CD14 molecule
chr9_-_95166841 0.25 ENST00000262551.4
OGN
osteoglycin
chr9_-_95166884 0.24 ENST00000375561.5
OGN
osteoglycin
chr5_-_64777685 0.24 ENST00000536360.1
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr11_-_133715394 0.24 ENST00000299140.3
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr1_-_185597619 0.23 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr3_-_183735731 0.23 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_+_32811861 0.23 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr1_-_8000872 0.22 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr2_+_27760247 0.22 ENST00000447166.1
AC109829.1
Uncharacterized protein
chr22_+_44761431 0.22 ENST00000406912.1
RP1-32I10.10
Uncharacterized protein
chr4_-_155533787 0.22 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr16_+_19467772 0.22 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr3_+_111260856 0.22 ENST00000352690.4
CD96
CD96 molecule
chr3_-_126327398 0.22 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_-_140013275 0.21 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr19_+_35168547 0.21 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr19_-_44952635 0.21 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr19_-_10613862 0.21 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr3_-_71114066 0.21 ENST00000485326.2
FOXP1
forkhead box P1
chr7_-_33842742 0.21 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
RP11-89N17.4
chr12_+_113587558 0.21 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr18_+_18822216 0.20 ENST00000269218.6
GREB1L
growth regulation by estrogen in breast cancer-like
chr18_+_6729698 0.20 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr2_+_95831529 0.20 ENST00000295210.6
ENST00000453539.2
ZNF2
zinc finger protein 2
chr19_-_56904799 0.20 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582
zinc finger protein 582
chr17_-_27038063 0.20 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr18_+_61143994 0.19 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr14_+_100240019 0.19 ENST00000556199.1
EML1
echinoderm microtubule associated protein like 1
chr9_+_100069933 0.19 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr5_+_53686658 0.19 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr17_-_34207295 0.19 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_-_32821599 0.19 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_38210644 0.19 ENST00000394128.2
ENST00000394127.2
ENST00000356271.3
ENST00000535071.2
ENST00000580885.1
ENST00000543759.2
ENST00000537674.2
ENST00000580517.1
ENST00000578161.1
MED24
mediator complex subunit 24
chr10_+_81065975 0.18 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chr16_-_1660662 0.18 ENST00000569646.1
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr19_+_57106647 0.18 ENST00000328070.6
ZNF71
zinc finger protein 71
chr14_+_55034599 0.17 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr2_-_84686552 0.16 ENST00000393868.2
SUCLG1
succinate-CoA ligase, alpha subunit
chr14_-_81408063 0.16 ENST00000557411.1
CEP128
centrosomal protein 128kDa
chr3_+_122296465 0.16 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr2_+_68961934 0.16 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr11_+_118175132 0.16 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr2_+_68961905 0.16 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr15_+_45021183 0.16 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr3_-_194119995 0.15 ENST00000323007.3
GP5
glycoprotein V (platelet)
chr5_-_95018660 0.15 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr6_-_116833500 0.15 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr19_+_57106624 0.15 ENST00000599599.1
ZNF71
zinc finger protein 71
chr15_-_60690163 0.15 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2
annexin A2
chr6_+_139349903 0.15 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr14_+_20811722 0.15 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr10_+_6625733 0.15 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr1_-_226065330 0.15 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr17_-_58603482 0.14 ENST00000585368.1
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr5_+_137203541 0.14 ENST00000421631.2
MYOT
myotilin
chr12_-_55367331 0.14 ENST00000526532.1
ENST00000532757.1
TESPA1
thymocyte expressed, positive selection associated 1
chr10_-_6622201 0.14 ENST00000539722.1
ENST00000397176.2
PRKCQ
protein kinase C, theta
chr6_+_108977520 0.14 ENST00000540898.1
FOXO3
forkhead box O3
chr12_+_20848282 0.14 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr15_-_75660919 0.14 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1
mannosidase, alpha, class 2C, member 1
chr14_+_96722539 0.14 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr4_+_130017268 0.13 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr6_-_166581333 0.13 ENST00000366876.2
T
T, brachyury homolog (mouse)
chr19_+_35168633 0.13 ENST00000505365.2
ZNF302
zinc finger protein 302
chr14_+_20811766 0.13 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr7_-_41740181 0.13 ENST00000442711.1
INHBA
inhibin, beta A
chr6_+_31540056 0.13 ENST00000418386.2
LTA
lymphotoxin alpha
chr19_+_44669280 0.13 ENST00000590089.1
ENST00000454662.2
ZNF226
zinc finger protein 226
chr21_+_38593701 0.12 ENST00000440629.1
AP001432.14
AP001432.14
chr16_+_58283814 0.12 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr7_+_10000640 0.12 ENST00000451755.1
AC006373.1
AC006373.1
chr1_-_144364246 0.12 ENST00000540273.1
PPIAL4B
peptidylprolyl isomerase A (cyclophilin A)-like 4B
chr9_-_95166976 0.12 ENST00000447356.1
OGN
osteoglycin
chr5_+_137203557 0.12 ENST00000515645.1
MYOT
myotilin
chr14_+_35591020 0.12 ENST00000603611.1
KIAA0391
KIAA0391
chr5_+_137203465 0.12 ENST00000239926.4
MYOT
myotilin
chrX_-_63005405 0.11 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr12_+_27396901 0.11 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr13_-_41240717 0.11 ENST00000379561.5
FOXO1
forkhead box O1
chr15_-_60690932 0.11 ENST00000559818.1
ANXA2
annexin A2
chr14_-_35591156 0.11 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr9_-_116163400 0.11 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD
aminolevulinate dehydratase
chr1_+_149553003 0.11 ENST00000369222.3
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chrX_+_54834159 0.11 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr19_+_50529212 0.11 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473
zinc finger protein 473
chr1_+_214163033 0.11 ENST00000607425.1
PROX1
prospero homeobox 1
chr17_+_7358889 0.10 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chrX_+_24711997 0.10 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr5_-_16509101 0.10 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr10_-_50396357 0.10 ENST00000453436.1
ENST00000474718.1
C10orf128
chromosome 10 open reading frame 128
chr20_+_5731083 0.10 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr3_+_130064359 0.10 ENST00000432398.2
ENST00000265379.6
COL6A5
collagen, type VI, alpha 5
chr12_+_56435637 0.10 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr11_+_73003824 0.09 ENST00000538328.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_+_38179969 0.09 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
MYD88
myeloid differentiation primary response 88
chr1_+_179699318 0.09 ENST00000423879.1
RP11-12M5.1
RP11-12M5.1
chr19_+_35168567 0.09 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
ZNF302
zinc finger protein 302

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.4 1.1 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.3 0.8 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 1.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 1.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 1.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.6 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.8 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.5 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.3 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.1 0.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.5 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.3 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 1.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:2000110 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.3 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0070417 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) cellular response to cold(GO:0070417)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:1902230 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.3 GO:0032059 bleb(GO:0032059)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 1.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 3.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.5 GO:0002102 podosome(GO:0002102)
0.0 1.6 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 1.0 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.1 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.5 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 1.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 1.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling