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Illumina Body Map 2, young vs old

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Results for STAT5A

Z-value: 0.24

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Transcription factors associated with STAT5A

Gene Symbol Gene ID Gene Info
ENSG00000126561.12 signal transducer and activator of transcription 5A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Ahg19_v2_chr17_+_40440481_404405610.029.3e-01Click!

Activity profile of STAT5A motif

Sorted Z-values of STAT5A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_50649192 5.72 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chr1_-_36937075 5.46 ENST00000464465.2
colony stimulating factor 3 receptor (granulocyte)
chr12_-_15082050 5.14 ENST00000540097.1
endoplasmic reticulum protein 27
chr3_+_111260954 5.05 ENST00000283285.5
CD96 molecule
chr4_+_155484103 4.79 ENST00000302068.4
fibrinogen beta chain
chr4_-_155511887 4.61 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr2_+_90198535 4.57 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr2_-_89292422 4.50 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr17_-_33864772 4.46 ENST00000361112.4
schlafen family member 12-like
chr1_-_36948879 4.35 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
colony stimulating factor 3 receptor (granulocyte)
chr3_+_111260980 4.16 ENST00000438817.2
CD96 molecule
chr14_+_22320634 3.94 ENST00000390435.1
T cell receptor alpha variable 8-3
chr10_-_6104253 3.84 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
interleukin 2 receptor, alpha
chr1_-_162381907 3.83 ENST00000367929.2
ENST00000359567.3
SH2 domain containing 1B
chrX_+_78426469 3.78 ENST00000276077.1
G protein-coupled receptor 174
chr15_+_58430567 3.75 ENST00000536493.1
aquaporin 9
chr2_-_89399845 3.71 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_-_89160770 3.66 ENST00000390240.2
immunoglobulin kappa joining 3
chr12_+_10705960 3.62 ENST00000544591.1
RP11-291B21.2
chr7_+_142008340 3.62 ENST00000390387.3
T cell receptor beta variable 3-1
chr4_+_155484155 3.61 ENST00000509493.1
fibrinogen beta chain
chr12_-_10151773 3.59 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr7_-_142198049 3.58 ENST00000471935.1
T cell receptor beta variable 11-2
chr1_-_159046617 3.57 ENST00000368130.4
absent in melanoma 2
chr4_+_40194570 3.57 ENST00000507851.1
ras homolog family member H
chr19_+_47835404 3.49 ENST00000595464.1
complement component 5a receptor 2
chr6_+_131894284 3.39 ENST00000368087.3
ENST00000356962.2
arginase 1
chr7_-_36634181 3.38 ENST00000538464.1
acyloxyacyl hydrolase (neutrophil)
chr19_+_52264104 3.33 ENST00000340023.6
formyl peptide receptor 2
chr9_-_97402531 3.29 ENST00000415431.1
fructose-1,6-bisphosphatase 1
chr14_+_22111077 3.19 ENST00000390423.2
T cell receptor alpha variable 1-2
chr2_-_75796837 3.18 ENST00000233712.1
eva-1 homolog A (C. elegans)
chr4_-_71532207 3.16 ENST00000543780.1
ENST00000391614.3
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr9_-_97402413 3.11 ENST00000414122.1
fructose-1,6-bisphosphatase 1
chr8_-_134114721 3.06 ENST00000522119.1
ENST00000523610.1
ENST00000521302.1
ENST00000519558.1
ENST00000519747.1
ENST00000517648.1
Src-like-adaptor
chr4_-_71532601 3.03 ENST00000510614.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr3_+_111260856 3.02 ENST00000352690.4
CD96 molecule
chr14_+_22180536 3.02 ENST00000390424.2
T cell receptor alpha variable 2
chr1_+_158901329 3.00 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr4_-_71532339 3.00 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_-_139727118 2.98 ENST00000484111.1
poly (ADP-ribose) polymerase family, member 12
chr4_-_71532668 2.97 ENST00000510437.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr8_-_6836156 2.97 ENST00000382679.2
defensin, alpha 1
chr11_-_111320706 2.97 ENST00000531398.1
POU class 2 associating factor 1
chr3_+_50649302 2.96 ENST00000446044.1
mitogen-activated protein kinase-activated protein kinase 3
chr16_+_27413483 2.95 ENST00000337929.3
ENST00000564089.1
interleukin 21 receptor
chr12_+_66696322 2.93 ENST00000247815.4
helicase (DNA) B
chr18_-_67624160 2.90 ENST00000581982.1
ENST00000280200.4
CD226 molecule
chr19_+_55361898 2.83 ENST00000326321.3
ENST00000270442.5
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
chr19_+_18284477 2.83 ENST00000407280.3
interferon, gamma-inducible protein 30
chr1_+_159770292 2.81 ENST00000536257.1
ENST00000321935.6
Fc receptor-like 6
chr8_-_134114866 2.81 ENST00000524345.1
Src-like-adaptor
chr2_+_7865923 2.80 ENST00000417930.1
AC092580.4
chr2_-_89161432 2.79 ENST00000390242.2
immunoglobulin kappa joining 1
chr22_-_42828375 2.76 ENST00000329021.5
NFAT activating protein with ITAM motif 1
chr3_-_120365866 2.74 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr19_-_51875894 2.73 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr17_-_34207295 2.72 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr1_-_161600822 2.69 ENST00000534776.1
ENST00000540048.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr14_-_25103472 2.69 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr17_-_64216748 2.63 ENST00000585162.1
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_38858428 2.63 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
toll-like receptor 6
toll-like receptor 1
chr2_+_218989991 2.62 ENST00000453237.1
chemokine (C-X-C motif) receptor 2
chr2_+_90139056 2.61 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr18_-_67623906 2.61 ENST00000583955.1
CD226 molecule
chr14_+_23009190 2.59 ENST00000390532.1
T cell receptor alpha joining 5
chr5_-_138725594 2.54 ENST00000302125.8
marginal zone B and B1 cell-specific protein
chr8_-_134114887 2.54 ENST00000519341.1
Src-like-adaptor
chr1_+_158801095 2.53 ENST00000368141.4
myeloid cell nuclear differentiation antigen
chr12_-_54689532 2.51 ENST00000540264.2
ENST00000312156.4
nuclear factor, erythroid 2
chr19_-_10446449 2.50 ENST00000592439.1
intercellular adhesion molecule 3
chr16_+_30485267 2.50 ENST00000569725.1
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr14_+_22458631 2.50 ENST00000390444.1
T cell receptor alpha variable 16
chr14_-_25103388 2.47 ENST00000526004.1
ENST00000415355.3
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr5_-_138725560 2.44 ENST00000412103.2
ENST00000457570.2
marginal zone B and B1 cell-specific protein
chr11_-_104893863 2.43 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
caspase 5, apoptosis-related cysteine peptidase
chr14_+_22204418 2.41 ENST00000390426.2
T cell receptor alpha variable 4
chr2_+_163200848 2.40 ENST00000233612.4
grancalcin, EF-hand calcium binding protein
chr2_-_89340242 2.37 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr7_-_142224280 2.37 ENST00000390367.3
T cell receptor beta variable 11-1
chr7_+_150382781 2.34 ENST00000223293.5
ENST00000474605.1
GTPase, IMAP family member 2
chr2_-_89160117 2.34 ENST00000390238.2
immunoglobulin kappa joining 5
chr6_-_31560729 2.33 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
natural cytotoxicity triggering receptor 3
chr3_-_172019686 2.32 ENST00000596321.1
Uncharacterized protein
chr1_+_111415757 2.32 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr12_+_8666126 2.32 ENST00000299665.2
C-type lectin domain family 4, member D
chr12_-_15103621 2.31 ENST00000536592.1
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_161600990 2.29 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr1_-_161600942 2.29 ENST00000421702.2
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr15_-_38856836 2.29 ENST00000450598.2
ENST00000559830.1
ENST00000558164.1
ENST00000310803.5
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr6_-_154567984 2.28 ENST00000517438.1
interaction protein for cytohesin exchange factors 1
chrY_+_15016725 2.28 ENST00000336079.3
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_+_81043000 2.27 ENST00000482617.1
RP11-6B4.1
chr4_-_165305086 2.27 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_-_30654977 2.27 ENST00000399199.3
protein phosphatase 1, regulatory subunit 18
chr3_-_52864680 2.26 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr19_+_55327923 2.24 ENST00000391728.4
ENST00000326542.7
ENST00000358178.4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
chr2_+_135596180 2.23 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr17_-_72619869 2.22 ENST00000392619.1
ENST00000426295.2
CD300e molecule
chr4_+_40194609 2.22 ENST00000508513.1
ras homolog family member H
chr17_-_72619783 2.21 ENST00000328630.3
CD300e molecule
chr10_+_26727125 2.19 ENST00000376236.4
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_-_37026108 2.19 ENST00000396045.3
engulfment and cell motility 1
chr16_-_21663919 2.17 ENST00000569602.1
immunoglobulin superfamily, member 6
chr11_-_104827425 2.16 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr19_+_55235969 2.16 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr14_+_22554680 2.14 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr4_+_40195262 2.12 ENST00000503941.1
ras homolog family member H
chr7_+_139529040 2.12 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr7_-_36764004 2.12 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chrY_+_22737604 2.10 ENST00000361365.2
eukaryotic translation initiation factor 1A, Y-linked
chr22_+_23247030 2.09 ENST00000390324.2
immunoglobulin lambda joining 3
chr8_-_133772870 2.08 ENST00000522334.1
ENST00000519016.1
transmembrane protein 71
chr1_-_161519579 2.08 ENST00000426740.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr12_-_45269769 2.07 ENST00000548826.1
NEL-like 2 (chicken)
chr18_-_67629015 2.07 ENST00000579496.1
CD226 molecule
chr22_-_37640456 2.07 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_247582097 2.06 ENST00000391827.2
NLR family, pyrin domain containing 3
chr2_+_90259593 2.04 ENST00000471857.1
immunoglobulin kappa variable 1D-8
chrY_+_15016013 2.04 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_+_40841276 2.04 ENST00000254691.5
caspase recruitment domain family, member 6
chr3_+_38179969 2.04 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
myeloid differentiation primary response 88
chr2_-_89161064 2.02 ENST00000390241.2
immunoglobulin kappa joining 2
chr7_+_139528952 2.01 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr14_-_25078864 1.99 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr4_-_153601136 1.99 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr5_-_140013275 1.99 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14 molecule
chr10_+_6625605 1.98 ENST00000414894.1
ENST00000449648.1
PRKCQ antisense RNA 1
chr7_+_74188309 1.98 ENST00000289473.4
ENST00000433458.1
neutrophil cytosolic factor 1
chr6_-_116866773 1.97 ENST00000368602.3
trafficking protein particle complex 3-like
chr3_-_71777824 1.96 ENST00000469524.1
eukaryotic translation initiation factor 4E family member 3
chr19_-_8567505 1.96 ENST00000600262.1
PML-RARA regulated adaptor molecule 1
chr21_+_34602680 1.96 ENST00000447980.1
interferon (alpha, beta and omega) receptor 2
chr1_-_226065330 1.96 ENST00000436966.1
transmembrane protein 63A
chr5_-_140013224 1.95 ENST00000498971.2
CD14 molecule
chr8_-_133772794 1.92 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr14_-_94919103 1.91 ENST00000334708.3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr2_+_90192768 1.91 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr22_-_37640277 1.90 ENST00000401529.3
ENST00000249071.6
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_+_102196739 1.90 ENST00000556973.1
Uncharacterized protein
chr18_-_67624412 1.89 ENST00000580335.1
CD226 molecule
chr4_-_38806404 1.88 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
toll-like receptor 1
chr17_-_76356148 1.88 ENST00000587578.1
ENST00000330871.2
suppressor of cytokine signaling 3
chr16_-_67517716 1.88 ENST00000290953.2
agouti related protein homolog (mouse)
chr5_-_140013241 1.87 ENST00000519715.1
CD14 molecule
chr1_-_167487758 1.87 ENST00000362089.5
CD247 molecule
chr12_-_45269430 1.87 ENST00000395487.2
NEL-like 2 (chicken)
chr5_-_169694286 1.87 ENST00000521416.1
ENST00000520344.1
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_+_135730297 1.87 ENST00000370629.2
CD40 ligand
chr19_+_55281260 1.87 ENST00000336077.6
ENST00000291633.7
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
chr4_+_108815402 1.86 ENST00000503385.1
sphingomyelin synthase 2
chr22_+_22385332 1.86 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr12_+_20963647 1.86 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr16_-_21663950 1.86 ENST00000268389.4
immunoglobulin superfamily, member 6
chr3_-_112218378 1.85 ENST00000334529.5
B and T lymphocyte associated
chr14_-_106805716 1.84 ENST00000438142.2
immunoglobulin heavy variable 4-31
chr22_+_23222886 1.84 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr14_+_22538811 1.84 ENST00000390450.3
T cell receptor alpha variable 22
chr2_-_113594279 1.83 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr10_-_72362515 1.83 ENST00000373209.2
ENST00000441259.1
perforin 1 (pore forming protein)
chr6_+_31540056 1.82 ENST00000418386.2
lymphotoxin alpha
chr14_+_22591276 1.82 ENST00000390455.3
T cell receptor alpha variable 26-1
chr12_-_45270077 1.81 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr16_+_50730910 1.81 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr22_+_25003626 1.80 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
gamma-glutamyltransferase 1
chr7_+_139529085 1.80 ENST00000539806.1
thromboxane A synthase 1 (platelet)
chr2_+_85804614 1.79 ENST00000263864.5
ENST00000409760.1
vesicle-associated membrane protein 8
chr12_-_45269251 1.79 ENST00000553120.1
NEL-like 2 (chicken)
chr6_-_32151999 1.77 ENST00000375069.3
ENST00000538695.1
ENST00000438221.2
ENST00000375065.5
ENST00000450110.1
ENST00000375067.3
ENST00000375056.2
advanced glycosylation end product-specific receptor
chr19_-_8567478 1.77 ENST00000255612.3
PML-RARA regulated adaptor molecule 1
chr12_+_56324933 1.77 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr22_-_24096562 1.76 ENST00000398465.3
pre-B lymphocyte 3
chr17_-_26697304 1.74 ENST00000536498.1
vitronectin
chr22_+_23010756 1.74 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr22_+_23241661 1.73 ENST00000390322.2
immunoglobulin lambda joining 2
chr11_+_58695174 1.73 ENST00000317391.4
glycine-N-acyltransferase-like 1
chr2_-_207583120 1.73 ENST00000452335.2
dystrotelin
chr22_-_50523807 1.73 ENST00000442311.1
ENST00000538737.1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_-_179499108 1.72 ENST00000521389.1
ring finger protein 130
chr22_-_50523843 1.70 ENST00000535444.1
ENST00000431262.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr4_-_185820602 1.70 ENST00000515864.1
ENST00000507183.1
long intergenic non-protein coding RNA 1093
chr10_-_6019552 1.70 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr19_+_51728316 1.69 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33 molecule
chr7_+_117120017 1.69 ENST00000003084.6
ENST00000454343.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr2_+_135596106 1.68 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr1_-_161519682 1.68 ENST00000367969.3
ENST00000443193.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_+_128563652 1.67 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr7_-_29186008 1.67 ENST00000396276.3
ENST00000265394.5
carboxypeptidase, vitellogenic-like
chr19_-_7764960 1.67 ENST00000593418.1
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr14_+_21249200 1.67 ENST00000304677.2
ribonuclease, RNase A family, k6
chr19_+_55128576 1.66 ENST00000396331.1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr5_-_147211190 1.66 ENST00000510027.2
serine peptidase inhibitor, Kazal type 1
chr14_+_22675388 1.65 ENST00000390461.2
T cell receptor alpha variable 34
chr12_-_103352144 1.65 ENST00000551337.1
phenylalanine hydroxylase
chr11_+_121461097 1.64 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_85932760 1.64 ENST00000565552.1
interferon regulatory factor 8
chr9_-_123812542 1.64 ENST00000223642.1
complement component 5
chr7_-_38315919 1.64 ENST00000390339.1
T cell receptor gamma joining P1
chr5_-_13944652 1.64 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr22_-_50523688 1.64 ENST00000450140.2
megalencephalic leukoencephalopathy with subcortical cysts 1

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
2.0 6.0 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
1.6 6.4 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.6 9.5 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
1.6 4.7 GO:1904604 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
1.5 3.0 GO:0035915 pore formation in membrane of other organism(GO:0035915)
1.5 5.8 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.2 3.5 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
1.1 1.1 GO:2001179 interleukin-10 secretion(GO:0072608) regulation of interleukin-10 secretion(GO:2001179)
1.0 3.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.9 13.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.9 1.8 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.9 5.2 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.8 5.0 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.8 4.8 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.8 2.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.8 2.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.8 5.3 GO:0071461 cellular response to redox state(GO:0071461)
0.8 8.3 GO:0070269 pyroptosis(GO:0070269)
0.7 3.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.7 3.6 GO:0019303 D-ribose catabolic process(GO:0019303)
0.7 1.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 2.9 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.7 2.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.7 3.4 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.7 2.0 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.7 8.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.6 1.9 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.6 5.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.6 1.9 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.6 2.6 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 3.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.6 3.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.6 1.8 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6 3.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.5 1.6 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.5 3.7 GO:0008218 bioluminescence(GO:0008218)
0.5 3.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5 1.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.5 1.6 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.5 5.6 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.5 2.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.5 2.0 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.5 1.4 GO:0061580 colon epithelial cell migration(GO:0061580)
0.5 8.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.5 1.9 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.5 2.7 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.4 2.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.4 2.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 2.6 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.4 1.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 4.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.4 1.2 GO:1903413 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.4 1.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.4 1.5 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.4 5.7 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.4 1.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.4 1.4 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.3 1.0 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.3 2.3 GO:0032252 secretory granule localization(GO:0032252)
0.3 2.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.9 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.3 1.3 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.3 2.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 2.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 0.9 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 6.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 0.9 GO:0070839 spleen trabecula formation(GO:0060345) divalent metal ion export(GO:0070839) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 3.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 0.9 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 3.2 GO:0018377 protein myristoylation(GO:0018377)
0.3 0.9 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.3 2.9 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 5.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 4.8 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.3 1.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 0.6 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.3 1.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.3 1.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 4.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 1.6 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.3 1.9 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.3 0.8 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 0.8 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.3 0.8 GO:0061485 memory T cell proliferation(GO:0061485)
0.3 2.1 GO:0032621 interleukin-18 production(GO:0032621)
0.3 2.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 1.0 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.3 2.1 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.3 0.8 GO:0042938 dipeptide transport(GO:0042938)
0.3 9.8 GO:0097186 amelogenesis(GO:0097186)
0.3 0.5 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 2.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.0 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.2 1.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 2.8 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 3.7 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.2 1.6 GO:0072679 thymocyte migration(GO:0072679)
0.2 0.6 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.6 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 0.8 GO:0042369 vitamin D catabolic process(GO:0042369)
0.2 0.2 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.2 0.8 GO:1990637 response to prolactin(GO:1990637)
0.2 4.4 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.2 0.6 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.6 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 6.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.2 1.7 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.2 1.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 0.9 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.7 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.2 3.0 GO:0044351 macropinocytosis(GO:0044351)
0.2 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.7 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.2 0.7 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.2 0.9 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.2 1.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2 0.3 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.2 1.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2 2.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 0.5 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 0.2 GO:0060061 Spemann organizer formation(GO:0060061)
0.2 1.5 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 3.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 0.3 GO:0070426 nitric oxide production involved in inflammatory response(GO:0002537) positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 1.0 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 0.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.9 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.2 1.1 GO:1902896 terminal web assembly(GO:1902896)
0.2 2.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 2.7 GO:0015747 urate transport(GO:0015747)
0.2 1.7 GO:0019530 taurine metabolic process(GO:0019530)
0.2 1.4 GO:0000023 maltose metabolic process(GO:0000023)
0.2 0.6 GO:0006788 heme oxidation(GO:0006788)
0.2 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 2.0 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.2 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.6 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.1 1.6 GO:0035855 megakaryocyte development(GO:0035855)
0.1 4.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 7.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.6 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.6 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 8.1 GO:1900077 negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.4 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.8 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 2.8 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 33.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 1.6 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.6 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 0.4 GO:0071400 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 1.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.7 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 1.8 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 3.5 GO:0045730 respiratory burst(GO:0045730)
0.1 1.3 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 11.5 GO:0045576 mast cell activation(GO:0045576)
0.1 1.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.1 0.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 2.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 1.9 GO:0007172 signal complex assembly(GO:0007172)
0.1 1.6 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 1.0 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1 1.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.9 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 7.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.0 GO:0046618 drug export(GO:0046618)
0.1 0.9 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.6 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 2.5 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.5 GO:0007059 chromosome segregation(GO:0007059)
0.1 0.9 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.5 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 1.8 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.6 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.4 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.1 0.9 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.1 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 1.0 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 2.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.7 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 2.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 10.7 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.6 GO:0001555 oocyte growth(GO:0001555)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.2 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 4.4 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.5 GO:0090156 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 3.7 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.9 GO:0045064 T-helper 2 cell differentiation(GO:0045064)
0.1 0.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 1.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 3.6 GO:0030220 platelet formation(GO:0030220)
0.1 1.1 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.5 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.6 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.7 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 2.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.5 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.7 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.1 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.9 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 0.3 GO:0039521 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 2.8 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.7 GO:0002385 mucosal immune response(GO:0002385)
0.1 1.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 0.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.6 GO:0034201 response to oleic acid(GO:0034201)
0.1 1.5 GO:0015816 glycine transport(GO:0015816)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.8 GO:0001554 luteolysis(GO:0001554)
0.1 1.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.9 GO:0032620 interleukin-17 production(GO:0032620)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415)
0.1 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.9 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.7 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 1.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.1 GO:0036376 sodium ion export from cell(GO:0036376)
0.1 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.2 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.2 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 2.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 11.2 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.5 GO:0071436 sodium ion export(GO:0071436)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 5.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.5 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.1 0.7 GO:0042246 tissue regeneration(GO:0042246)
0.1 1.2 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 0.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 1.2 GO:0071467 cellular response to pH(GO:0071467)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 1.7 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.3 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.1 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.3 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 3.7 GO:0006968 cellular defense response(GO:0006968)
0.1 0.8 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 1.3 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.7 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 1.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 4.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 2.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 2.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.7 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.9 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 2.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 2.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.6 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 2.3 GO:0030101 natural killer cell activation(GO:0030101)
0.0 1.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.7 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.0 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 2.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.3 GO:0060068 vagina development(GO:0060068)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.0 1.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0021915 neural tube development(GO:0021915)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.9 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 1.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0006569 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.6 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.9 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 1.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.9 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.5 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.3 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.4 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 1.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 6.9 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 14.3 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)
0.0 1.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 1.4 GO:0007140 male meiosis(GO:0007140)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.9 GO:0006909 phagocytosis(GO:0006909)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 1.0 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.4 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.1 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 1.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 2.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 2.9 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.0 GO:0006956 complement activation(GO:0006956)
0.0 1.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.5 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0006506 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.0 9.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
1.0 13.6 GO:0005577 fibrinogen complex(GO:0005577)
0.7 6.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.7 3.3 GO:0036398 TCR signalosome(GO:0036398)
0.6 2.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.6 2.2 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.5 1.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.5 2.9 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.4 1.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.4 1.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.4 2.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.4 2.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 7.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 3.4 GO:0032010 phagolysosome(GO:0032010)
0.3 1.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 2.9 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 5.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 1.8 GO:0044194 cytolytic granule(GO:0044194)
0.3 2.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 1.0 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 1.0 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 1.0 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.7 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.2 16.7 GO:0001772 immunological synapse(GO:0001772)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 2.5 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 5.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 4.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.9 GO:0002079 inner acrosomal membrane(GO:0002079)
0.2 1.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 0.7 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.8 GO:0070701 mucus layer(GO:0070701)
0.2 0.5 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 4.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 5.1 GO:0042629 mast cell granule(GO:0042629)
0.1 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.2 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.9 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.6 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 1.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.6 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 20.8 GO:0035579 specific granule membrane(GO:0035579)
0.1 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:1990769 proximal neuron projection(GO:1990769)
0.1 2.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 14.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0016600 flotillin complex(GO:0016600)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.9 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.6 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 6.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.0 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 2.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 28.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 1.5 GO:0042599 lamellar body(GO:0042599)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 4.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 1.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 3.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 1.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 5.3 GO:0005901 caveola(GO:0005901)
0.1 4.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.1 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 3.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 4.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 2.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 5.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.5 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 8.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 3.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 2.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.9 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 5.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 8.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.0 GO:0032991 macromolecular complex(GO:0032991)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 2.2 GO:0044432 endoplasmic reticulum part(GO:0044432)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.4 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 2.9 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 7.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.8 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 22.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 9.8 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
1.6 6.4 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.6 4.7 GO:1904599 advanced glycation end-product binding(GO:1904599)
1.5 5.9 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.4 5.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.2 6.2 GO:0004905 type I interferon receptor activity(GO:0004905)
1.2 6.0 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
1.2 3.5 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.1 1.1 GO:0001855 complement component C4b binding(GO:0001855)
1.1 3.4 GO:0005174 CD40 receptor binding(GO:0005174)
1.0 6.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
1.0 2.9 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
1.0 5.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.9 3.6 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.8 3.2 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.8 3.8 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.7 3.7 GO:0015254 glycerol channel activity(GO:0015254)
0.7 3.0 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.7 2.9 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.7 2.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.7 13.0 GO:0019864 IgG binding(GO:0019864)
0.6 1.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.5 1.6 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.5 3.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.5 1.9 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 5.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 2.6 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.4 2.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.4 6.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 1.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.4 2.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.1 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.4 4.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.4 1.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.4 1.4 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3 6.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 1.0 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.3 1.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.3 2.0 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 1.3 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.3 2.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 2.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 1.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 0.9 GO:0097689 iron channel activity(GO:0097689)
0.3 0.9 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.3 4.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 2.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 2.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 2.8 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.3 1.6 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.3 6.8 GO:0050700 CARD domain binding(GO:0050700)
0.3 3.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 0.8 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.9 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 0.8 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 1.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 7.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.0 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 0.7 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 7.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.1 GO:0051525 NFAT protein binding(GO:0051525)
0.2 1.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.6 GO:0046979 TAP2 binding(GO:0046979)
0.2 5.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 3.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 2.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 1.8 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 1.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 3.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.2 4.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 3.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.3 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 1.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.2 1.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 1.6 GO:0019863 IgE binding(GO:0019863)
0.2 1.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 0.5 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.2 1.0 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 0.5 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 0.8 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 2.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.0 GO:0004797 thymidine kinase activity(GO:0004797)
0.2 1.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.2 1.4 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.2 0.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.2 37.0 GO:0003823 antigen binding(GO:0003823)
0.2 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 3.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.9 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.6 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 3.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 3.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.7 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.9 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 2.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.6 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0052835 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 3.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 1.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 2.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 1.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.3 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.6 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 2.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.4 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 10.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 1.9 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 2.3 GO:0005123 death receptor binding(GO:0005123)
0.1 1.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 2.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.8 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.3 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.0 GO:0015266 protein channel activity(GO:0015266)
0.1 4.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 3.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 1.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 6.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.6 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 2.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 9.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 3.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.3 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 3.8 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 3.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 1.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.7 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 5.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 4.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 1.8 GO:0017166 vinculin binding(GO:0017166)
0.0 2.2 GO:0016773 phosphotransferase activity, alcohol group as acceptor(GO:0016773)
0.0 7.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 2.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0035276 ethanol binding(GO:0035276)
0.0 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0036122 BMP binding(GO:0036122)
0.0 6.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.5 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 2.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 10.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.9 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 1.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 3.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0046935 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0008233 peptidase activity(GO:0008233)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 8.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.3 22.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 14.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 11.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 9.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 1.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 4.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 8.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 10.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 7.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 4.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 14.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 5.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 5.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 5.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 5.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.9 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 6.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 4.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 8.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 51.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 6.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 9.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 4.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 1.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 7.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 7.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.2 2.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 9.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 4.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 7.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 7.9 REACTOME DEFENSINS Genes involved in Defensins
0.2 2.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 7.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 6.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 6.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 8.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 5.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 8.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 6.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 0.7 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 4.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 4.1 REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.6 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.1 2.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 3.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 2.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 2.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 4.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 2.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 2.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.6 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 1.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 5.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)