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Illumina Body Map 2, young vs old

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Results for STAT5B

Z-value: 0.46

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Transcription factors associated with STAT5B

Gene Symbol Gene ID Gene Info
STAT5B
ENSG00000173757.5 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT5Bhg19_v2_chr17_-_40428359_40428462-0.232.0e-01Click!

Activity profile of STAT5B motif

Sorted Z-values of STAT5B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_50523843 2.85 ENST00000535444.1
ENST00000431262.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_-_151047327 2.84 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr22_-_50523807 2.78 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523688 2.58 ENST00000450140.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_-_26697304 2.31 ENST00000536498.1
VTN
vitronectin
chr1_+_149754227 2.16 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr22_-_50523760 2.09 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_37213554 1.98 ENST00000443735.1
PVALB
parvalbumin
chr6_+_116782527 1.95 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr12_+_21207503 1.94 ENST00000545916.1
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_-_55367361 1.93 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr2_+_17721230 1.90 ENST00000457525.1
VSNL1
visinin-like 1
chr12_-_55367331 1.88 ENST00000526532.1
ENST00000532757.1
TESPA1
thymocyte expressed, positive selection associated 1
chr4_+_155484155 1.85 ENST00000509493.1
FGB
fibrinogen beta chain
chr19_+_44556158 1.85 ENST00000434772.3
ENST00000585552.1
ZNF223
zinc finger protein 223
chr4_-_155511887 1.85 ENST00000302053.3
ENST00000403106.3
FGA
fibrinogen alpha chain
chr4_+_155484103 1.83 ENST00000302068.4
FGB
fibrinogen beta chain
chr1_-_120935894 1.80 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr11_+_27062860 1.74 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_-_104145795 1.73 ENST00000259407.2
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chrX_+_107288280 1.67 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr19_-_44405623 1.52 ENST00000591815.1
RP11-15A1.3
RP11-15A1.3
chr5_-_111093081 1.51 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr7_+_110731062 1.49 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr11_+_27062502 1.47 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_+_6051526 1.46 ENST00000378111.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_-_49016847 1.42 ENST00000598924.1
CTC-273B12.10
CTC-273B12.10
chr18_-_67629015 1.40 ENST00000579496.1
CD226
CD226 molecule
chr3_-_130745403 1.39 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1 (Drosophila)
chr6_-_135818764 1.38 ENST00000488690.2
AHI1
Abelson helper integration site 1
chr1_+_159770292 1.37 ENST00000536257.1
ENST00000321935.6
FCRL6
Fc receptor-like 6
chr19_+_44488330 1.36 ENST00000591532.1
ENST00000407951.2
ENST00000270014.2
ENST00000590615.1
ENST00000586454.1
ZNF155
zinc finger protein 155
chr19_+_51152702 1.34 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr14_+_22180536 1.28 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr5_-_111093167 1.28 ENST00000446294.2
ENST00000419114.2
NREP
neuronal regeneration related protein
chr7_-_134001663 1.26 ENST00000378509.4
SLC35B4
solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
chr19_+_44617511 1.26 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr9_-_99637820 1.24 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr5_-_111092930 1.22 ENST00000257435.7
NREP
neuronal regeneration related protein
chr19_+_44669280 1.21 ENST00000590089.1
ENST00000454662.2
ZNF226
zinc finger protein 226
chr19_+_44529479 1.17 ENST00000587846.1
ENST00000187879.8
ENST00000391960.3
ZNF222
zinc finger protein 222
chr12_+_120740119 1.11 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr19_-_58326267 1.11 ENST00000391701.1
ZNF552
zinc finger protein 552
chr6_+_52226897 1.09 ENST00000442253.2
PAQR8
progestin and adipoQ receptor family member VIII
chr3_-_130745571 1.06 ENST00000514044.1
ENST00000264992.3
ASTE1
asteroid homolog 1 (Drosophila)
chr19_+_44507091 1.06 ENST00000429154.2
ENST00000585632.1
ZNF230
zinc finger protein 230
chr7_+_47834880 1.05 ENST00000258776.4
C7orf69
chromosome 7 open reading frame 69
chr5_-_111092873 1.03 ENST00000509025.1
ENST00000515855.1
NREP
neuronal regeneration related protein
chr16_+_69984810 1.00 ENST00000393701.2
ENST00000568461.1
CLEC18A
C-type lectin domain family 18, member A
chr1_+_155051305 0.99 ENST00000368408.3
EFNA3
ephrin-A3
chr6_+_28048753 0.99 ENST00000377325.1
ZNF165
zinc finger protein 165
chr19_-_3801789 0.97 ENST00000590849.1
ENST00000395045.2
MATK
megakaryocyte-associated tyrosine kinase
chrX_-_70474910 0.96 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_111093340 0.95 ENST00000508870.1
NREP
neuronal regeneration related protein
chr14_-_68162464 0.95 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr19_-_45004556 0.95 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180
zinc finger protein 180
chr19_+_35225060 0.94 ENST00000599244.1
ENST00000392232.3
ZNF181
zinc finger protein 181
chr19_+_45445491 0.94 ENST00000592954.1
ENST00000419266.2
ENST00000589057.1
APOC4
APOC4-APOC2
apolipoprotein C-IV
APOC4-APOC2 readthrough (NMD candidate)
chr12_+_14369524 0.93 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chr11_-_82997420 0.93 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr19_-_44439387 0.92 ENST00000269973.5
ZNF45
zinc finger protein 45
chr19_+_38085768 0.92 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr19_-_56904799 0.92 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582
zinc finger protein 582
chr19_+_58258164 0.90 ENST00000317178.5
ZNF776
zinc finger protein 776
chr3_-_181160240 0.90 ENST00000460993.1
RP11-275H4.1
RP11-275H4.1
chr19_+_40503013 0.90 ENST00000595225.1
ZNF546
zinc finger protein 546
chr1_-_112106556 0.90 ENST00000443498.1
ADORA3
adenosine A3 receptor
chr16_+_70207686 0.90 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
CLEC18C
C-type lectin domain family 18, member C
chr19_+_38085731 0.89 ENST00000589117.1
ZNF540
zinc finger protein 540
chr15_+_69854027 0.89 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr16_+_76343743 0.88 ENST00000478060.1
CNTNAP4
contactin associated protein-like 4
chr9_+_104161123 0.88 ENST00000374861.3
ENST00000339664.2
ENST00000259395.4
ZNF189
zinc finger protein 189
chrY_+_2709906 0.88 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr9_+_123906331 0.86 ENST00000431571.1
CNTRL
centriolin
chr2_-_170430366 0.86 ENST00000453153.2
ENST00000445210.1
FASTKD1
FAST kinase domains 1
chr3_+_156799587 0.86 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr1_-_112106578 0.85 ENST00000369717.4
ADORA3
adenosine A3 receptor
chr19_+_44669221 0.85 ENST00000590578.1
ENST00000589160.1
ENST00000337433.5
ENST00000586286.1
ENST00000585560.1
ENST00000586914.1
ENST00000588883.1
ENST00000413984.2
ENST00000588742.1
ENST00000300823.6
ENST00000585678.1
ENST00000586203.1
ENST00000590467.1
ENST00000588795.1
ENST00000588127.1
ZNF226
zinc finger protein 226
chrX_+_107288197 0.84 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_+_10197463 0.84 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr14_-_68162438 0.82 ENST00000557273.1
ENST00000428130.2
RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr2_-_170430277 0.81 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr19_+_40502938 0.81 ENST00000599504.1
ENST00000596894.1
ENST00000601138.1
ENST00000600094.1
ENST00000347077.4
ZNF546
zinc finger protein 546
chr12_+_21284118 0.81 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr2_-_207583120 0.80 ENST00000452335.2
DYTN
dystrotelin
chr19_-_58090240 0.80 ENST00000196489.3
ZNF416
zinc finger protein 416
chr6_-_25874440 0.79 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr1_+_40997233 0.79 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
ZNF684
zinc finger protein 684
chr12_+_133656995 0.79 ENST00000356456.5
ZNF140
zinc finger protein 140
chr19_-_44405941 0.78 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr8_+_93895865 0.77 ENST00000391681.1
AC117834.1
AC117834.1
chr19_+_58038683 0.77 ENST00000240719.3
ENST00000376233.3
ENST00000594943.1
ENST00000602149.1
ZNF549
zinc finger protein 549
chrY_+_2709527 0.76 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr1_+_155051379 0.74 ENST00000418360.2
EFNA3
ephrin-A3
chr20_+_34556488 0.74 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr4_+_74347400 0.74 ENST00000226355.3
AFM
afamin
chr3_-_183735651 0.74 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chrX_+_107288239 0.73 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr19_-_37406923 0.73 ENST00000520965.1
ZNF829
zinc finger protein 829
chr13_+_52436111 0.71 ENST00000242819.4
CCDC70
coiled-coil domain containing 70
chr19_-_4902877 0.70 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr19_+_35225121 0.70 ENST00000595708.1
ENST00000593781.1
ZNF181
zinc finger protein 181
chr12_+_133657461 0.67 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
ZNF140
zinc finger protein 140
chr19_+_44598534 0.66 ENST00000336976.6
ZNF224
zinc finger protein 224
chr19_+_13229126 0.66 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr17_-_16472483 0.66 ENST00000395824.1
ENST00000448349.2
ENST00000395825.3
ZNF287
zinc finger protein 287
chr19_+_15783879 0.65 ENST00000551607.1
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr19_-_38183201 0.65 ENST00000590008.1
ENST00000358582.4
ZNF781
zinc finger protein 781
chr6_-_27440460 0.63 ENST00000377419.1
ZNF184
zinc finger protein 184
chr2_-_37193606 0.62 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr9_-_115774453 0.61 ENST00000427548.1
ZNF883
zinc finger protein 883
chr1_-_168464875 0.60 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr19_-_37407172 0.60 ENST00000391711.3
ZNF829
zinc finger protein 829
chr19_-_37958318 0.59 ENST00000316950.6
ENST00000591710.1
ZNF569
zinc finger protein 569
chr19_-_57988871 0.59 ENST00000596831.1
ENST00000601768.1
ENST00000356584.3
ENST00000600175.1
ENST00000425074.3
ENST00000343280.4
ENST00000427512.2
AC004076.9
ZNF772
Uncharacterized protein
zinc finger protein 772
chr16_-_20710212 0.58 ENST00000523065.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr9_+_100069933 0.58 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr19_-_37157713 0.57 ENST00000592829.1
ENST00000591370.1
ENST00000588268.1
ENST00000360357.4
ZNF461
zinc finger protein 461
chr9_+_130186653 0.57 ENST00000342483.5
ENST00000543471.1
ZNF79
zinc finger protein 79
chr6_+_135818979 0.56 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
LINC00271
long intergenic non-protein coding RNA 271
chr17_+_15603447 0.56 ENST00000395893.2
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr10_-_127505167 0.56 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr2_-_214017151 0.55 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr1_-_146054494 0.54 ENST00000401009.2
NBPF11
neuroblastoma breakpoint family, member 11
chr11_-_87908600 0.54 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr6_+_84569359 0.53 ENST00000369681.5
ENST00000369679.4
CYB5R4
cytochrome b5 reductase 4
chr13_-_99404875 0.53 ENST00000376503.5
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr11_+_73357614 0.53 ENST00000536527.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr16_-_53737795 0.53 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr19_+_44598492 0.52 ENST00000589680.1
ZNF224
zinc finger protein 224
chr2_+_63816295 0.52 ENST00000539945.1
ENST00000544381.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr6_-_27440837 0.52 ENST00000211936.6
ZNF184
zinc finger protein 184
chr7_-_93633658 0.52 ENST00000433727.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr14_-_77889860 0.52 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chrX_+_106045891 0.51 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1D8B
TBC1 domain family, member 8B (with GRAM domain)
chr20_+_54987305 0.51 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr2_+_63816269 0.51 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr9_-_104160872 0.51 ENST00000539624.1
ENST00000374865.4
MRPL50
mitochondrial ribosomal protein L50
chr2_+_63816126 0.50 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr15_+_22833395 0.49 ENST00000283645.4
TUBGCP5
tubulin, gamma complex associated protein 5
chr13_+_115079949 0.49 ENST00000361283.1
CHAMP1
chromosome alignment maintaining phosphoprotein 1
chr7_-_93633684 0.49 ENST00000222547.3
ENST00000425626.1
BET1
Bet1 golgi vesicular membrane trafficking protein
chr2_+_172290707 0.49 ENST00000375255.3
ENST00000539783.1
DCAF17
DDB1 and CUL4 associated factor 17
chr11_+_2920951 0.49 ENST00000347936.2
SLC22A18
solute carrier family 22, member 18
chr2_+_27760247 0.49 ENST00000447166.1
AC109829.1
Uncharacterized protein
chr7_+_99102267 0.49 ENST00000326775.5
ENST00000451158.1
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr19_+_58258202 0.48 ENST00000431353.1
ZNF776
zinc finger protein 776
chr6_+_2245982 0.47 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS-AS1
GMDS antisense RNA 1 (head to head)
chr19_-_44905741 0.46 ENST00000591679.1
ENST00000544719.2
ENST00000330997.4
ENST00000585868.1
ENST00000588212.1
ZNF285
CTC-512J12.6
zinc finger protein 285
Uncharacterized protein
chr11_-_82997371 0.46 ENST00000525503.1
CCDC90B
coiled-coil domain containing 90B
chr19_+_13228917 0.46 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_+_63816087 0.46 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr8_+_27632047 0.44 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr4_+_40195262 0.44 ENST00000503941.1
RHOH
ras homolog family member H
chr19_-_36980337 0.44 ENST00000434377.2
ENST00000424129.2
ENST00000452939.1
ENST00000427002.1
ZNF566
zinc finger protein 566
chr15_+_22833482 0.43 ENST00000453949.2
TUBGCP5
tubulin, gamma complex associated protein 5
chr6_-_32784687 0.42 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr11_-_67374177 0.41 ENST00000333139.3
C11orf72
chromosome 11 open reading frame 72
chr9_-_113100088 0.41 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr12_-_133532864 0.41 ENST00000536932.1
ENST00000360187.4
ENST00000392321.3
CHFR
ZNF605
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
zinc finger protein 605
chr4_+_40194570 0.40 ENST00000507851.1
RHOH
ras homolog family member H
chr19_-_56826157 0.40 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
ZSCAN5A
zinc finger and SCAN domain containing 5A
chr16_-_89785777 0.39 ENST00000561976.1
VPS9D1
VPS9 domain containing 1
chr11_-_61124266 0.38 ENST00000539890.1
CYB561A3
cytochrome b561 family, member A3
chr19_+_44645700 0.38 ENST00000592437.1
ZNF234
zinc finger protein 234
chr9_-_70488865 0.37 ENST00000377392.5
CBWD5
COBW domain containing 5
chr19_-_58220517 0.37 ENST00000512439.2
ENST00000426889.1
ZNF154
zinc finger protein 154
chr11_-_115127611 0.37 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr19_+_56368803 0.37 ENST00000587891.1
NLRP4
NLR family, pyrin domain containing 4
chr19_+_39881951 0.37 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr2_-_142888573 0.36 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr15_+_42066740 0.36 ENST00000514566.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr16_+_50914085 0.36 ENST00000576842.1
CTD-2034I21.2
CTD-2034I21.2
chr4_+_25378912 0.35 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr8_-_56685859 0.35 ENST00000523423.1
ENST00000523073.1
ENST00000519784.1
ENST00000434581.2
ENST00000519780.1
ENST00000521229.1
ENST00000522576.1
ENST00000523180.1
ENST00000522090.1
TMEM68
transmembrane protein 68
chr19_-_36980455 0.34 ENST00000454319.1
ENST00000392170.2
ZNF566
zinc finger protein 566
chr19_-_58427944 0.34 ENST00000312026.5
ENST00000536263.1
ENST00000598629.1
ENST00000595559.1
ENST00000597515.1
ENST00000599251.1
ENST00000598526.1
ZNF417
zinc finger protein 417
chr5_-_177423243 0.33 ENST00000308304.2
PROP1
PROP paired-like homeobox 1
chr20_+_54987168 0.33 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr7_+_142985308 0.33 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr2_+_238877424 0.33 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr5_+_178450753 0.33 ENST00000444149.2
ENST00000519896.1
ENST00000522442.1
ZNF879
zinc finger protein 879
chr3_+_169940153 0.33 ENST00000295797.4
PRKCI
protein kinase C, iota
chr4_+_86396265 0.33 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr4_+_25378826 0.32 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chr8_-_56685966 0.32 ENST00000334667.2
TMEM68
transmembrane protein 68
chr3_-_183735731 0.31 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_-_37958086 0.31 ENST00000592490.1
ENST00000392149.2
ZNF569
zinc finger protein 569
chr5_+_118668846 0.31 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_-_87564620 0.31 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr17_+_38097727 0.30 ENST00000377924.4
LRRC3C
leucine rich repeat containing 3C
chr5_+_32585605 0.30 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chr5_+_68856035 0.30 ENST00000512736.1
ENST00000510979.1
ENST00000514162.1
ENST00000380729.3
ENST00000508344.2
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr8_+_27632083 0.29 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr17_+_57784826 0.29 ENST00000262291.4
VMP1
vacuole membrane protein 1
chr4_+_130017268 0.29 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr19_+_37341260 0.29 ENST00000589046.1
ZNF345
zinc finger protein 345
chr19_+_44764031 0.29 ENST00000592581.1
ENST00000590668.1
ENST00000588489.1
ENST00000391958.2
ZNF233
zinc finger protein 233
chr2_-_44223089 0.29 ENST00000447246.1
ENST00000409946.1
ENST00000409659.1
LRPPRC
leucine-rich pentatricopeptide repeat containing
chr7_-_108096822 0.29 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT5B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.5 10.3 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.5 1.4 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.4 1.8 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 5.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.3 1.3 GO:1990569 GDP-fucose transport(GO:0015783) UDP-N-acetylglucosamine transport(GO:0015788) purine nucleotide-sugar transport(GO:0036079) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 3.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.4 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.2 0.6 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.5 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.6 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.7 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 1.7 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.7 GO:0003095 pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360)
0.1 2.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 2.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 3.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 2.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.2 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.7 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.2 GO:0015747 urate transport(GO:0015747)
0.1 2.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.6 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 1.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.5 GO:0046618 drug export(GO:0046618)
0.1 1.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 1.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.8 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 3.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0015781 nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.4 5.5 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.5 GO:1990031 pinceau fiber(GO:1990031)
0.2 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.9 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 10.5 GO:0005901 caveola(GO:0005901)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 3.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 4.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.6 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.5 2.0 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.3 1.1 GO:0047708 biotinidase activity(GO:0047708)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.3 1.3 GO:0005462 GDP-fucose transmembrane transporter activity(GO:0005457) UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.2 1.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 0.8 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.2 0.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.7 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.5 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 1.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 4.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 1.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 2.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.8 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 2.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.5 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.1 1.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 1.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 9.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 1.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0015165 nucleotide-sugar transmembrane transporter activity(GO:0005338) pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 3.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 1.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 4.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 3.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 24.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.0 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling