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Illumina Body Map 2, young vs old

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Results for TBP

Z-value: 0.38

Motif logo

Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863421_170863484-0.183.3e-01Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_59043166 11.92 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr16_+_82068830 10.46 ENST00000199936.4
hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_18287721 10.28 ENST00000356524.4
serum amyloid A1
chr11_+_18287801 10.25 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr15_+_45722727 10.01 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
chromosome 15 open reading frame 48
chr17_-_34345002 10.00 ENST00000293280.2
chemokine (C-C motif) ligand 23
chr1_+_159557607 9.55 ENST00000255040.2
amyloid P component, serum
chr7_+_142829162 9.48 ENST00000291009.3
prolactin-induced protein
chr19_+_46367518 8.42 ENST00000302177.2
forkhead box A3
chr17_-_34344991 8.40 ENST00000591423.1
chemokine (C-C motif) ligand 23
chr21_-_43735628 7.93 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr11_-_5248294 7.84 ENST00000335295.4
hemoglobin, beta
chr11_-_18270182 7.71 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
serum amyloid A2
chr3_-_165555200 7.57 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr21_-_43735446 7.29 ENST00000398431.2
trefoil factor 3 (intestinal)
chr8_-_6735451 7.21 ENST00000297439.3
defensin, beta 1
chr16_+_82068585 7.15 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_169703203 7.13 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr11_+_43964055 6.86 ENST00000528572.1
chromosome 11 open reading frame 96
chr16_+_82068873 6.78 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr3_+_148583043 6.76 ENST00000296046.3
carboxypeptidase A3 (mast cell)
chr18_-_61329118 6.72 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr6_+_25727046 6.69 ENST00000274764.2
histone cluster 1, H2ba
chr10_-_81320151 6.65 ENST00000372325.2
ENST00000372327.5
ENST00000417041.1
surfactant protein A2
chr12_+_13044787 6.65 ENST00000534831.1
G protein-coupled receptor, family C, group 5, member A
chr17_-_39661849 6.63 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
keratin 13
chr9_+_117092149 6.59 ENST00000431067.2
ENST00000412657.1
orosomucoid 2
chr2_-_151344172 6.54 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
Rho family GTPase 3
chr9_+_130911723 6.44 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
lipocalin 2
chr3_+_149192475 6.22 ENST00000465758.1
transmembrane 4 L six family member 4
chr17_-_39780634 6.10 ENST00000577817.2
keratin 17
chr19_+_11650709 6.06 ENST00000586059.1
calponin 1, basic, smooth muscle
chr11_-_102651343 5.97 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr17_-_39780819 5.89 ENST00000311208.8
keratin 17
chr20_+_3052264 5.83 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr5_-_42812143 5.81 ENST00000514985.1
selenoprotein P, plasma, 1
chr13_+_53602894 5.74 ENST00000219022.2
olfactomedin 4
chr16_+_2880369 5.74 ENST00000572863.1
zymogen granule protein 16B
chr17_-_48278983 5.62 ENST00000225964.5
collagen, type I, alpha 1
chr17_+_32683456 5.59 ENST00000225844.2
chemokine (C-C motif) ligand 13
chr9_+_130911770 5.53 ENST00000372998.1
lipocalin 2
chr10_+_96698406 5.52 ENST00000260682.6
cytochrome P450, family 2, subfamily C, polypeptide 9
chr5_+_78407602 5.32 ENST00000274353.5
ENST00000524080.1
betaine--homocysteine S-methyltransferase
chr15_-_62457480 5.31 ENST00000380392.3
C2 calcium-dependent domain containing 4B
chr14_-_25045446 5.29 ENST00000216336.2
cathepsin G
chr21_-_43786634 5.29 ENST00000291527.2
trefoil factor 1
chr1_-_168698433 5.26 ENST00000367817.3
dermatopontin
chrX_-_101771645 5.18 ENST00000289373.4
thymosin beta 15a
chr11_-_5255861 4.92 ENST00000380299.3
hemoglobin, delta
chr20_+_31823792 4.88 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPI fold containing family A, member 1
chr12_-_11463353 4.85 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
proline-rich protein BstNI subfamily 4
chr20_-_43883197 4.81 ENST00000338380.2
secretory leukocyte peptidase inhibitor
chr17_+_32612687 4.80 ENST00000305869.3
chemokine (C-C motif) ligand 11
chr11_-_102714534 4.79 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr11_-_5255696 4.76 ENST00000292901.3
ENST00000417377.1
hemoglobin, delta
chr12_-_11508520 4.72 ENST00000545626.1
ENST00000500254.2
proline-rich protein BstNI subfamily 1
chr3_+_193853927 4.63 ENST00000232424.3
hes family bHLH transcription factor 1
chr17_-_39781054 4.57 ENST00000463128.1
keratin 17
chr17_-_48546232 4.53 ENST00000258969.4
chondroadherin
chr6_-_25726781 4.48 ENST00000297012.3
histone cluster 1, H2aa
chr5_-_42811986 4.47 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr17_-_48546324 4.46 ENST00000508540.1
chondroadherin
chr20_+_30193083 4.41 ENST00000376112.3
ENST00000376105.3
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr16_+_78056412 4.09 ENST00000299642.4
ENST00000575655.1
C-type lectin domain family 3, member A
chr4_-_74904398 4.09 ENST00000296026.4
chemokine (C-X-C motif) ligand 3
chr11_-_116694009 4.07 ENST00000357780.3
apolipoprotein A-IV
chr16_+_2014941 3.88 ENST00000531523.1
small nucleolar RNA host gene 9 (non-protein coding)
chr11_-_2950642 3.86 ENST00000314222.4
pleckstrin homology-like domain, family A, member 2
chr19_-_36247910 3.80 ENST00000587965.1
ENST00000004982.3
heat shock protein, alpha-crystallin-related, B6
chr12_+_50355647 3.77 ENST00000293599.6
aquaporin 5
chr12_-_15038779 3.73 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr1_-_159684371 3.72 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
C-reactive protein, pentraxin-related
chr16_+_2880157 3.71 ENST00000382280.3
zymogen granule protein 16B
chr1_+_86046433 3.65 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr1_+_161228517 3.64 ENST00000504449.1
Purkinje cell protein 4 like 1
chr17_-_39661947 3.64 ENST00000590425.1
keratin 13
chr9_-_33447584 3.61 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr1_-_161193349 3.57 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr15_-_41166414 3.54 ENST00000220507.4
ras homolog family member V
chr16_+_57406368 3.52 ENST00000006053.6
ENST00000563383.1
chemokine (C-X3-C motif) ligand 1
chr1_+_152881014 3.49 ENST00000368764.3
ENST00000392667.2
involucrin
chr11_+_68451943 3.47 ENST00000265643.3
galanin/GMAP prepropeptide
chr15_-_50558223 3.42 ENST00000267845.3
histidine decarboxylase
chr8_+_66955648 3.39 ENST00000522619.1
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr2_-_85895295 3.36 ENST00000428225.1
ENST00000519937.2
surfactant protein B
chr6_+_71104588 3.34 ENST00000418403.1
RP11-462G2.1
chr1_-_117753540 3.33 ENST00000328189.3
ENST00000369458.3
V-set domain containing T cell activation inhibitor 1
chr19_-_6720686 3.32 ENST00000245907.6
complement component 3
chr12_-_91539918 3.29 ENST00000548218.1
decorin
chr12_-_11036844 3.27 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr12_+_11081828 3.25 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chrX_-_45629661 3.24 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr4_+_74702214 3.22 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr2_-_89521942 3.19 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr22_+_23029188 3.15 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr3_+_142342228 3.13 ENST00000337777.3
plastin 1
chrX_-_105282712 3.12 ENST00000372563.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_+_40909354 3.10 ENST00000313164.9
complement component 7
chr2_-_89292422 3.07 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr11_-_2160611 3.07 ENST00000416167.2
insulin-like growth factor 2 (somatomedin A)
chr9_-_34691201 3.05 ENST00000378800.3
ENST00000311925.2
chemokine (C-C motif) ligand 19
chr10_-_90712520 3.03 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr10_+_7745232 3.00 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_21757774 2.99 ENST00000261195.2
glycogen synthase 2 (liver)
chr2_+_135596106 2.96 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr17_-_38545799 2.96 ENST00000577541.1
topoisomerase (DNA) II alpha 170kDa
chr18_+_56887381 2.94 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
gastrin-releasing peptide
chr20_+_36932521 2.92 ENST00000262865.4
bactericidal/permeability-increasing protein
chr16_+_56685796 2.91 ENST00000334346.2
ENST00000562399.1
metallothionein 1B
chr1_-_209825674 2.91 ENST00000367030.3
ENST00000356082.4
laminin, beta 3
chr2_-_89327228 2.91 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr4_-_110723134 2.89 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_110723194 2.89 ENST00000394635.3
complement factor I
chr11_-_2160180 2.89 ENST00000381406.4
insulin-like growth factor 2 (somatomedin A)
chr1_+_31885963 2.88 ENST00000373709.3
serine incorporator 2
chr16_+_57406437 2.87 ENST00000564948.1
chemokine (C-X3-C motif) ligand 1
chr1_+_192544857 2.86 ENST00000367459.3
ENST00000469578.2
regulator of G-protein signaling 1
chr6_-_133035185 2.84 ENST00000367928.4
vanin 1
chr10_+_124320156 2.83 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr6_-_26235206 2.78 ENST00000244534.5
histone cluster 1, H1d
chr8_-_23021533 2.77 ENST00000312584.3
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr22_+_39916558 2.76 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr2_-_190044480 2.75 ENST00000374866.3
collagen, type V, alpha 2
chr19_+_840963 2.75 ENST00000234347.5
proteinase 3
chr14_-_106478603 2.73 ENST00000390596.2
immunoglobulin heavy variable 4-4
chr17_-_38574169 2.72 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr3_-_170587974 2.71 ENST00000463836.1
ribosomal protein L22-like 1
chr15_-_50557863 2.69 ENST00000543581.1
histidine decarboxylase
chr4_-_110723335 2.66 ENST00000394634.2
complement factor I
chr2_-_238305397 2.64 ENST00000409809.1
collagen, type VI, alpha 3
chr16_-_15950868 2.61 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chr10_+_7745303 2.61 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_170588163 2.60 ENST00000295830.8
ribosomal protein L22-like 1
chr4_-_100140331 2.56 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
alcohol dehydrogenase 6 (class V)
chr1_-_8086343 2.54 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERBB receptor feedback inhibitor 1
chr8_-_6914251 2.54 ENST00000330590.2
defensin, alpha 5, Paneth cell-specific
chr10_-_99771079 2.52 ENST00000309155.3
cartilage acidic protein 1
chr19_+_10381769 2.52 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr7_-_94285472 2.51 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
sarcoglycan, epsilon
chr17_-_39041479 2.49 ENST00000167588.3
keratin 20
chr2_+_90211643 2.49 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr10_+_96522361 2.48 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr3_-_100712352 2.47 ENST00000471714.1
ENST00000284322.5
ABI family, member 3 (NESH) binding protein
chr7_-_94285511 2.47 ENST00000265735.7
sarcoglycan, epsilon
chr11_-_102826434 2.46 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr3_-_170587815 2.44 ENST00000466674.1
ribosomal protein L22-like 1
chr12_-_120765565 2.42 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr15_-_63674034 2.41 ENST00000344366.3
ENST00000422263.2
carbonic anhydrase XII
chr2_-_163008903 2.41 ENST00000418842.2
ENST00000375497.3
glucagon
chr1_-_156675535 2.40 ENST00000368221.1
cellular retinoic acid binding protein 2
chr11_+_1074870 2.40 ENST00000441003.2
ENST00000359061.5
mucin 2, oligomeric mucus/gel-forming
chr11_-_5276008 2.40 ENST00000336906.4
hemoglobin, gamma G
chr22_-_39715600 2.38 ENST00000427905.1
ENST00000402527.1
ENST00000216146.4
ribosomal protein L3
chr19_+_49468558 2.37 ENST00000331825.6
ferritin, light polypeptide
chr2_-_75426183 2.37 ENST00000409848.3
tachykinin receptor 1
chr17_+_77021702 2.36 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr8_+_99956759 2.36 ENST00000522510.1
ENST00000457907.2
odd-skipped related transciption factor 2
chr21_+_45905448 2.35 ENST00000449713.1
AP001065.15
chr14_-_55369525 2.35 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GTP cyclohydrolase 1
chr12_+_21284118 2.35 ENST00000256958.2
solute carrier organic anion transporter family, member 1B1
chr7_-_41742697 2.33 ENST00000242208.4
inhibin, beta A
chr7_+_75931861 2.32 ENST00000248553.6
heat shock 27kDa protein 1
chr14_-_47120956 2.31 ENST00000298283.3
ribosomal protein L10-like
chr3_-_194090460 2.31 ENST00000428839.1
ENST00000347624.3
leucine rich repeat containing 15
chr16_+_2880254 2.29 ENST00000570670.1
zymogen granule protein 16B
chr12_-_52867569 2.27 ENST00000252250.6
keratin 6C
chr1_-_153518270 2.26 ENST00000354332.4
ENST00000368716.4
S100 calcium binding protein A4
chr2_+_135596180 2.25 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr5_-_169816638 2.24 ENST00000521859.1
ENST00000274629.4
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr1_+_37940153 2.23 ENST00000373087.6
zinc finger CCCH-type containing 12A
chr10_+_5135981 2.21 ENST00000380554.3
aldo-keto reductase family 1, member C3
chr17_+_56315787 2.21 ENST00000262290.4
ENST00000421678.2
lactoperoxidase
chr7_-_7575477 2.20 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr12_-_92539614 2.17 ENST00000256015.3
B-cell translocation gene 1, anti-proliferative
chr16_+_202686 2.16 ENST00000252951.2
hemoglobin, zeta
chr6_+_33239787 2.16 ENST00000439602.2
ENST00000474973.1
ribosomal protein S18
chr4_+_129730779 2.15 ENST00000226319.6
jade family PHD finger 1
chr12_-_53074182 2.15 ENST00000252244.3
keratin 1
chr11_-_2182388 2.13 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr16_+_71392616 2.10 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
calbindin 2
chr1_+_55446465 2.10 ENST00000371268.3
transmembrane protein 61
chr10_+_22634384 2.10 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
sperm associated antigen 6
chr1_-_935361 2.08 ENST00000484667.2
hes family bHLH transcription factor 4
chr17_+_32646055 2.08 ENST00000394620.1
chemokine (C-C motif) ligand 8
chr10_+_54074033 2.07 ENST00000373970.3
dickkopf WNT signaling pathway inhibitor 1
chr16_+_56659687 2.07 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr10_+_124320195 2.06 ENST00000359586.6
deleted in malignant brain tumors 1
chr19_-_14628645 2.05 ENST00000598235.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr7_-_94285402 2.05 ENST00000428696.2
ENST00000445866.2
sarcoglycan, epsilon
chr17_-_38859996 2.05 ENST00000264651.2
keratin 24
chr12_+_56435637 2.01 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr6_-_27114577 1.99 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr9_-_104198042 1.97 ENST00000374855.4
aldolase B, fructose-bisphosphate
chr12_+_50344516 1.97 ENST00000199280.3
ENST00000550862.1
aquaporin 2 (collecting duct)
chr5_-_153857819 1.96 ENST00000231121.2
heart and neural crest derivatives expressed 1
chr12_-_11548496 1.94 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr9_+_136501478 1.94 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr17_-_39674668 1.92 ENST00000393981.3
keratin 15
chr16_+_67840986 1.92 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
translin-associated factor X interacting protein 1
chr12_-_52845910 1.91 ENST00000252252.3
keratin 6B

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0014016 neuroblast differentiation(GO:0014016)
2.4 12.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
2.2 9.0 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
2.1 6.4 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
2.0 6.1 GO:0001694 histamine biosynthetic process(GO:0001694)
2.0 7.8 GO:0030185 nitric oxide transport(GO:0030185)
1.9 5.8 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
1.9 5.6 GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
1.8 5.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
1.7 6.7 GO:0035425 autocrine signaling(GO:0035425)
1.5 4.6 GO:0060164 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
1.5 11.9 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.5 4.4 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
1.4 7.2 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.4 5.6 GO:0044691 tooth eruption(GO:0044691)
1.4 9.6 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
1.3 5.2 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.3 3.8 GO:0015670 carbon dioxide transport(GO:0015670)
1.2 8.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.2 4.9 GO:1900228 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.2 3.6 GO:1903413 cellular response to bile acid(GO:1903413)
1.2 6.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
1.2 3.5 GO:0018969 thiocyanate metabolic process(GO:0018969)
1.2 3.5 GO:0051795 positive regulation of catagen(GO:0051795)
1.1 3.3 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
1.0 2.1 GO:0003129 heart induction(GO:0003129) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
1.0 3.0 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
1.0 2.0 GO:0071288 cellular response to mercury ion(GO:0071288)
1.0 3.9 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
1.0 4.8 GO:0035962 response to interleukin-13(GO:0035962)
0.9 22.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.9 3.7 GO:0010193 response to ozone(GO:0010193)
0.9 2.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.9 2.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 3.6 GO:0070295 renal water absorption(GO:0070295)
0.8 0.8 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.8 2.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.8 2.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.8 5.3 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.7 5.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 2.2 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.7 2.2 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.7 5.7 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389)
0.7 2.1 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.7 3.5 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.7 2.7 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.7 6.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.7 2.0 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7 2.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.6 10.4 GO:0043587 tongue morphogenesis(GO:0043587)
0.6 42.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.6 16.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.6 15.7 GO:0015669 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.6 1.9 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.6 1.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.6 6.6 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.6 2.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.6 2.3 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.6 3.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.6 5.7 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.6 4.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.6 1.7 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.6 3.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.5 6.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.5 3.7 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.5 1.5 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.5 3.0 GO:0090131 mesenchyme migration(GO:0090131)
0.5 8.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.5 4.8 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.5 2.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.5 2.9 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.5 4.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.5 1.8 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.4 1.8 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.4 1.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.4 3.0 GO:1902896 terminal web assembly(GO:1902896)
0.4 5.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 9.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.4 2.9 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 9.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 1.6 GO:0018277 protein deamination(GO:0018277)
0.4 1.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.4 1.2 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.4 2.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.4 6.8 GO:0002003 angiotensin maturation(GO:0002003)
0.3 4.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 12.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 4.8 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.3 1.3 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 2.0 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 0.7 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.3 1.9 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.3 1.3 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.3 1.5 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.3 3.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 1.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 4.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 2.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 8.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.2 GO:0008050 female courtship behavior(GO:0008050)
0.3 8.2 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.3 6.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.3 1.4 GO:0035993 subthalamic nucleus development(GO:0021763) deltoid tuberosity development(GO:0035993) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.3 1.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.3 1.1 GO:0006566 threonine metabolic process(GO:0006566)
0.3 0.8 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.3 0.8 GO:1903991 positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.3 1.5 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 0.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.9 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 2.0 GO:0042436 tryptophan catabolic process(GO:0006569) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.2 1.8 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 0.7 GO:0030474 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.2 0.7 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2 3.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 3.4 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.2 0.6 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.2 1.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 0.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.2 1.6 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.2 6.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.5 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 2.0 GO:0050957 equilibrioception(GO:0050957)
0.2 2.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 1.8 GO:0034465 response to carbon monoxide(GO:0034465)
0.2 0.5 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.2 28.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 2.6 GO:0006069 ethanol oxidation(GO:0006069)
0.2 0.8 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 7.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 1.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 2.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.9 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.2 2.9 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 1.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 2.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.4 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.1 11.4 GO:0001895 retina homeostasis(GO:0001895)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.1 0.8 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.8 GO:0001878 response to yeast(GO:0001878)
0.1 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.5 GO:0002215 defense response to nematode(GO:0002215)
0.1 3.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.9 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945) cellular response to lithium ion(GO:0071285)
0.1 2.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 2.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 3.7 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.6 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 7.2 GO:0006953 acute-phase response(GO:0006953)
0.1 0.7 GO:0060686 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.9 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 3.3 GO:0030728 ovulation(GO:0030728)
0.1 4.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 2.9 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.8 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.1 0.7 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 15.2 GO:0070268 cornification(GO:0070268)
0.1 8.9 GO:0030574 collagen catabolic process(GO:0030574)
0.1 1.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.4 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 3.2 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.2 GO:0035106 operant conditioning(GO:0035106)
0.1 8.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 1.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 7.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 1.5 GO:0030903 notochord development(GO:0030903)
0.1 1.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 2.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.7 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.1 8.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.1 4.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.4 GO:0060356 leucine import(GO:0060356)
0.1 2.3 GO:0030261 chromosome condensation(GO:0030261)
0.1 3.8 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.4 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 1.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 5.3 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 1.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 3.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0019079 viral genome replication(GO:0019079)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.5 GO:0030238 male sex determination(GO:0030238) Leydig cell differentiation(GO:0033327)
0.0 4.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 5.6 GO:0007586 digestion(GO:0007586)
0.0 0.9 GO:0042755 eating behavior(GO:0042755)
0.0 2.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 7.4 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.9 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562) snRNA modification(GO:0040031)
0.0 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.9 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 1.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.7 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.4 GO:0031069 hair follicle morphogenesis(GO:0031069) epidermis morphogenesis(GO:0048730)
0.0 1.8 GO:0033260 nuclear DNA replication(GO:0033260)
0.0 0.7 GO:0016032 viral process(GO:0016032) multi-organism cellular process(GO:0044764)
0.0 4.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.8 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 1.8 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 5.5 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.2 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 2.3 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.7 GO:0051896 regulation of protein kinase B signaling(GO:0051896)
0.0 1.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.5 GO:0010468 regulation of gene expression(GO:0010468)
0.0 1.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 1.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.9 5.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
1.9 5.6 GO:0005584 collagen type I trimer(GO:0005584)
1.9 5.6 GO:0044299 C-fiber(GO:0044299)
1.2 7.2 GO:1990742 microvesicle(GO:1990742)
1.1 15.7 GO:0005833 hemoglobin complex(GO:0005833)
0.9 2.8 GO:0005588 collagen type V trimer(GO:0005588)
0.9 25.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.8 2.4 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.8 2.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.7 7.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.6 1.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 8.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 3.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.5 7.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 2.8 GO:1990037 Lewy body core(GO:1990037)
0.4 5.9 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.4 3.2 GO:0070876 SOSS complex(GO:0070876)
0.4 3.0 GO:1990357 terminal web(GO:1990357)
0.3 36.7 GO:0035580 specific granule lumen(GO:0035580)
0.3 10.0 GO:0042599 lamellar body(GO:0042599)
0.3 15.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 5.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 2.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 3.1 GO:0005579 membrane attack complex(GO:0005579)
0.3 0.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 2.9 GO:0005610 laminin-5 complex(GO:0005610)
0.3 15.7 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 18.7 GO:0045095 keratin filament(GO:0045095)
0.2 1.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 3.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 20.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.2 9.3 GO:0000786 nucleosome(GO:0000786)
0.1 17.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 14.5 GO:0005882 intermediate filament(GO:0005882)
0.1 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 10.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 24.4 GO:0072562 blood microparticle(GO:0072562)
0.1 1.4 GO:0045179 apical cortex(GO:0045179)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 53.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 3.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 5.5 GO:0001533 cornified envelope(GO:0001533)
0.1 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 138.0 GO:0005615 extracellular space(GO:0005615)
0.1 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.1 GO:0005921 gap junction(GO:0005921)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.7 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 2.0 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 1.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.8 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.5 GO:0000346 transcription export complex(GO:0000346)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 1.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 10.8 GO:0005925 focal adhesion(GO:0005925)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 24.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
2.6 18.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.4 7.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
2.3 11.3 GO:0033265 choline binding(GO:0033265)
2.1 16.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.8 5.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
1.4 5.7 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.3 5.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.3 7.8 GO:0030492 hemoglobin binding(GO:0030492)
1.3 11.4 GO:0001849 complement component C1q binding(GO:0001849)
1.2 6.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.2 3.5 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
1.2 5.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.1 5.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.8 3.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.8 15.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.8 3.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.7 2.2 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.7 3.6 GO:0015254 glycerol channel activity(GO:0015254)
0.7 10.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.6 2.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.5 28.4 GO:0042056 chemoattractant activity(GO:0042056)
0.5 4.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 9.5 GO:0019864 IgG binding(GO:0019864)
0.5 3.5 GO:0004966 galanin receptor activity(GO:0004966)
0.5 2.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 3.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.4 7.1 GO:0033691 sialic acid binding(GO:0033691)
0.4 2.5 GO:0045569 TRAIL binding(GO:0045569)
0.4 8.5 GO:0008009 chemokine activity(GO:0008009)
0.4 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 3.8 GO:0015250 water channel activity(GO:0015250)
0.4 3.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.4 5.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 9.0 GO:0019887 protein kinase regulator activity(GO:0019887)
0.3 5.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 5.6 GO:0019841 retinol binding(GO:0019841)
0.3 0.8 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 3.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 1.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 1.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2 2.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 3.0 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 0.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.9 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 3.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 1.5 GO:0046790 virion binding(GO:0046790)
0.2 7.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 9.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 2.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 2.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 2.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 2.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 2.4 GO:0008097 5S rRNA binding(GO:0008097)
0.2 25.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 13.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 3.6 GO:0008494 translation activator activity(GO:0008494)
0.1 4.4 GO:0070628 proteasome binding(GO:0070628)
0.1 1.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 1.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 2.5 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.7 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 9.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.7 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.5 GO:0035473 lipase binding(GO:0035473)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 34.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.5 GO:0046870 cadmium ion binding(GO:0046870)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 21.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 2.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 8.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 11.0 GO:0002020 protease binding(GO:0002020)
0.1 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 4.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 2.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 6.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 6.4 GO:0051087 chaperone binding(GO:0051087)
0.0 1.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 17.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.8 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 2.9 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 1.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 3.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 4.6 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 2.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.9 GO:0008083 growth factor activity(GO:0008083)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 6.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 21.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 28.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 3.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 12.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 3.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 14.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 2.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 12.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 6.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 7.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 7.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 16.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 7.0 ST ADRENERGIC Adrenergic Pathway
0.1 7.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 7.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.5 PID IL23 PATHWAY IL23-mediated signaling events
0.1 28.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 2.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 30.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 5.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 3.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 12.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 10.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 20.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.5 1.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.5 8.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 17.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 8.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 11.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 5.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 4.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 7.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 4.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.3 5.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 3.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 19.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 6.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 22.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 13.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 9.8 REACTOME DEFENSINS Genes involved in Defensins
0.2 5.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 3.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 9.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 3.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 3.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 7.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 5.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 7.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 15.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 6.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 4.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)