Project
Illumina Body Map 2, young vs old
Navigation
Downloads
Results for TBX2
Z-value: 0.09
Motif logo
Transcription factors associated with TBX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TBX2
|
ENSG00000121068.9 | T-box transcription factor 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TBX2 | hg19_v2_chr17_+_59477233_59477263 | -0.11 | 5.5e-01 | Click! |
Activity profile of TBX2 motif
Sorted Z-values of TBX2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_219031709 | 3.74 |
ENST00000295683.2
|
CXCR1
|
chemokine (C-X-C motif) receptor 1 |
| chrY_+_2709527 | 3.49 |
ENST00000250784.8
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1 |
| chrY_+_2709906 | 3.18 |
ENST00000430575.1
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1 |
| chr19_-_51875894 | 2.89 |
ENST00000600427.1
ENST00000595217.1 ENST00000221978.5 |
NKG7
|
natural killer cell group 7 sequence |
| chr5_+_54320078 | 2.69 |
ENST00000231009.2
|
GZMK
|
granzyme K (granzyme 3; tryptase II) |
| chr19_+_859425 | 2.68 |
ENST00000327726.6
|
CFD
|
complement factor D (adipsin) |
| chr6_+_131894284 | 2.37 |
ENST00000368087.3
ENST00000356962.2 |
ARG1
|
arginase 1 |
| chr19_+_859654 | 2.37 |
ENST00000592860.1
|
CFD
|
complement factor D (adipsin) |
| chr19_-_51875523 | 2.31 |
ENST00000593572.1
ENST00000595157.1 |
NKG7
|
natural killer cell group 7 sequence |
| chr3_-_44465475 | 1.97 |
ENST00000416124.1
|
LINC00694
|
long intergenic non-protein coding RNA 694 |
| chr2_+_171571827 | 1.93 |
ENST00000375281.3
|
SP5
|
Sp5 transcription factor |
| chr15_-_22448819 | 1.84 |
ENST00000604066.1
|
IGHV1OR15-1
|
immunoglobulin heavy variable 1/OR15-1 (non-functional) |
| chr12_-_7848364 | 1.78 |
ENST00000329913.3
|
GDF3
|
growth differentiation factor 3 |
| chr6_-_6225026 | 1.74 |
ENST00000445223.1
|
F13A1
|
coagulation factor XIII, A1 polypeptide |
| chr3_+_52811596 | 1.71 |
ENST00000542827.1
ENST00000273283.2 |
ITIH1
|
inter-alpha-trypsin inhibitor heavy chain 1 |
| chr7_-_142181009 | 1.61 |
ENST00000390368.2
|
TRBV6-5
|
T cell receptor beta variable 6-5 |
| chr1_+_203444887 | 1.57 |
ENST00000343110.2
|
PRELP
|
proline/arginine-rich end leucine-rich repeat protein |
| chr1_+_32716857 | 1.53 |
ENST00000482949.1
ENST00000495610.2 |
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr12_-_91348949 | 1.53 |
ENST00000358859.2
|
CCER1
|
coiled-coil glutamate-rich protein 1 |
| chr7_+_80253387 | 1.52 |
ENST00000438020.1
|
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr1_+_32716840 | 1.51 |
ENST00000336890.5
|
LCK
|
lymphocyte-specific protein tyrosine kinase |
| chr8_-_99955042 | 1.48 |
ENST00000519420.1
|
STK3
|
serine/threonine kinase 3 |
| chr1_-_150780757 | 1.48 |
ENST00000271651.3
|
CTSK
|
cathepsin K |
| chr20_-_1538319 | 1.47 |
ENST00000381621.1
|
SIRPD
|
signal-regulatory protein delta |
| chr7_-_142240014 | 1.46 |
ENST00000390363.2
|
TRBV9
|
T cell receptor beta variable 9 |
| chrX_-_70329118 | 1.44 |
ENST00000374188.3
|
IL2RG
|
interleukin 2 receptor, gamma |
| chr3_+_148447887 | 1.41 |
ENST00000475347.1
ENST00000474935.1 ENST00000461609.1 |
AGTR1
|
angiotensin II receptor, type 1 |
| chr6_+_391739 | 1.41 |
ENST00000380956.4
|
IRF4
|
interferon regulatory factor 4 |
| chr21_+_30502806 | 1.40 |
ENST00000399928.1
ENST00000399926.1 |
MAP3K7CL
|
MAP3K7 C-terminal like |
| chr7_-_142120321 | 1.37 |
ENST00000390377.1
|
TRBV7-7
|
T cell receptor beta variable 7-7 |
| chr15_-_35088340 | 1.34 |
ENST00000290378.4
|
ACTC1
|
actin, alpha, cardiac muscle 1 |
| chr22_+_40441456 | 1.33 |
ENST00000402203.1
|
TNRC6B
|
trinucleotide repeat containing 6B |
| chr4_+_124317940 | 1.32 |
ENST00000505319.1
ENST00000339241.1 |
SPRY1
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| chr10_-_99531709 | 1.31 |
ENST00000266066.3
|
SFRP5
|
secreted frizzled-related protein 5 |
| chr2_+_7865923 | 1.25 |
ENST00000417930.1
|
AC092580.4
|
AC092580.4 |
| chr21_+_30503282 | 1.24 |
ENST00000399925.1
|
MAP3K7CL
|
MAP3K7 C-terminal like |
| chr14_+_21236586 | 1.22 |
ENST00000326783.3
|
EDDM3B
|
epididymal protein 3B |
| chr7_-_142224280 | 1.20 |
ENST00000390367.3
|
TRBV11-1
|
T cell receptor beta variable 11-1 |
| chr1_+_154975110 | 1.20 |
ENST00000535420.1
ENST00000368426.3 |
ZBTB7B
|
zinc finger and BTB domain containing 7B |
| chr10_+_114135952 | 1.19 |
ENST00000356116.1
ENST00000433418.1 ENST00000354273.4 |
ACSL5
|
acyl-CoA synthetase long-chain family member 5 |
| chr19_-_39108643 | 1.18 |
ENST00000396857.2
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr1_+_20915409 | 1.17 |
ENST00000375071.3
|
CDA
|
cytidine deaminase |
| chr12_+_58148842 | 1.17 |
ENST00000266643.5
|
MARCH9
|
membrane-associated ring finger (C3HC4) 9 |
| chrX_+_123480194 | 1.16 |
ENST00000371139.4
|
SH2D1A
|
SH2 domain containing 1A |
| chr17_-_46657473 | 1.15 |
ENST00000332503.5
|
HOXB4
|
homeobox B4 |
| chr19_+_55235969 | 1.14 |
ENST00000402254.2
ENST00000538269.1 ENST00000541392.1 ENST00000291860.1 ENST00000396284.2 |
KIR3DL1
KIR3DL3
KIR2DL4
|
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
| chr16_+_12059050 | 1.13 |
ENST00000396495.3
|
TNFRSF17
|
tumor necrosis factor receptor superfamily, member 17 |
| chr19_-_39108568 | 1.13 |
ENST00000586296.1
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr4_+_155484155 | 1.13 |
ENST00000509493.1
|
FGB
|
fibrinogen beta chain |
| chr19_-_39108552 | 1.12 |
ENST00000591517.1
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1 |
| chr1_-_25256368 | 1.11 |
ENST00000308873.6
|
RUNX3
|
runt-related transcription factor 3 |
| chr4_+_155484103 | 1.10 |
ENST00000302068.4
|
FGB
|
fibrinogen beta chain |
| chrX_+_99899180 | 1.09 |
ENST00000373004.3
|
SRPX2
|
sushi-repeat containing protein, X-linked 2 |
| chr16_-_79634595 | 1.09 |
ENST00000326043.4
ENST00000393350.1 |
MAF
|
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| chr2_-_217724767 | 1.08 |
ENST00000236979.2
|
TNP1
|
transition protein 1 (during histone to protamine replacement) |
| chr5_+_35856951 | 1.07 |
ENST00000303115.3
ENST00000343305.4 ENST00000506850.1 ENST00000511982.1 |
IL7R
|
interleukin 7 receptor |
| chr10_+_114135004 | 1.05 |
ENST00000393081.1
|
ACSL5
|
acyl-CoA synthetase long-chain family member 5 |
| chr9_-_117150303 | 1.03 |
ENST00000312033.3
|
AKNA
|
AT-hook transcription factor |
| chr7_-_18067478 | 1.01 |
ENST00000506618.2
|
PRPS1L1
|
phosphoribosyl pyrophosphate synthetase 1-like 1 |
| chr14_-_21058982 | 1.00 |
ENST00000556526.1
|
RNASE12
|
ribonuclease, RNase A family, 12 (non-active) |
| chr7_-_27135591 | 1.00 |
ENST00000343060.4
ENST00000355633.5 |
HOXA1
|
homeobox A1 |
| chr1_-_207095212 | 0.99 |
ENST00000420007.2
|
FAIM3
|
Fas apoptotic inhibitory molecule 3 |
| chr2_+_102758751 | 0.99 |
ENST00000442590.1
|
IL1R1
|
interleukin 1 receptor, type I |
| chr16_+_12058961 | 0.99 |
ENST00000053243.1
|
TNFRSF17
|
tumor necrosis factor receptor superfamily, member 17 |
| chr12_+_52431016 | 0.98 |
ENST00000553200.1
|
NR4A1
|
nuclear receptor subfamily 4, group A, member 1 |
| chr12_+_93965609 | 0.98 |
ENST00000549887.1
ENST00000551556.1 |
SOCS2
|
suppressor of cytokine signaling 2 |
| chr19_+_52264104 | 0.97 |
ENST00000340023.6
|
FPR2
|
formyl peptide receptor 2 |
| chr16_+_31271274 | 0.97 |
ENST00000287497.8
ENST00000544665.3 |
ITGAM
|
integrin, alpha M (complement component 3 receptor 3 subunit) |
| chr1_-_1142067 | 0.96 |
ENST00000379268.2
|
TNFRSF18
|
tumor necrosis factor receptor superfamily, member 18 |
| chr8_-_101724989 | 0.96 |
ENST00000517403.1
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr17_-_7081435 | 0.96 |
ENST00000380920.4
|
ASGR1
|
asialoglycoprotein receptor 1 |
| chr19_-_10213335 | 0.96 |
ENST00000592641.1
ENST00000253109.4 |
ANGPTL6
|
angiopoietin-like 6 |
| chr15_-_55581954 | 0.95 |
ENST00000336787.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr1_+_167599532 | 0.95 |
ENST00000537350.1
|
RCSD1
|
RCSD domain containing 1 |
| chr1_-_22263790 | 0.93 |
ENST00000374695.3
|
HSPG2
|
heparan sulfate proteoglycan 2 |
| chr7_-_36764062 | 0.92 |
ENST00000435386.1
|
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr12_+_32112340 | 0.92 |
ENST00000540924.1
ENST00000312561.4 |
KIAA1551
|
KIAA1551 |
| chrX_+_70503037 | 0.92 |
ENST00000535149.1
|
NONO
|
non-POU domain containing, octamer-binding |
| chr12_+_57388230 | 0.91 |
ENST00000300098.1
|
GPR182
|
G protein-coupled receptor 182 |
| chr1_+_154975258 | 0.91 |
ENST00000417934.2
|
ZBTB7B
|
zinc finger and BTB domain containing 7B |
| chr5_+_38445641 | 0.89 |
ENST00000397210.3
ENST00000506135.1 ENST00000508131.1 |
EGFLAM
|
EGF-like, fibronectin type III and laminin G domains |
| chr5_+_137514403 | 0.89 |
ENST00000513276.1
|
KIF20A
|
kinesin family member 20A |
| chr15_+_94774767 | 0.89 |
ENST00000543482.1
|
MCTP2
|
multiple C2 domains, transmembrane 2 |
| chr12_+_47617284 | 0.89 |
ENST00000549630.1
ENST00000551777.1 |
PCED1B
|
PC-esterase domain containing 1B |
| chr2_+_234875252 | 0.88 |
ENST00000456930.1
|
TRPM8
|
transient receptor potential cation channel, subfamily M, member 8 |
| chr7_-_100239132 | 0.88 |
ENST00000223051.3
ENST00000431692.1 |
TFR2
|
transferrin receptor 2 |
| chr14_+_103058948 | 0.87 |
ENST00000262241.6
|
RCOR1
|
REST corepressor 1 |
| chr7_-_99381884 | 0.86 |
ENST00000336411.2
|
CYP3A4
|
cytochrome P450, family 3, subfamily A, polypeptide 4 |
| chr19_-_6670128 | 0.86 |
ENST00000245912.3
|
TNFSF14
|
tumor necrosis factor (ligand) superfamily, member 14 |
| chr10_-_131762105 | 0.86 |
ENST00000368648.3
ENST00000355311.5 |
EBF3
|
early B-cell factor 3 |
| chr14_-_24664540 | 0.86 |
ENST00000530563.1
ENST00000528895.1 ENST00000528669.1 ENST00000532632.1 |
TM9SF1
|
transmembrane 9 superfamily member 1 |
| chr11_-_414948 | 0.85 |
ENST00000530494.1
ENST00000528209.1 ENST00000431843.2 ENST00000528058.1 |
SIGIRR
|
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| chr1_+_101702417 | 0.85 |
ENST00000305352.6
|
S1PR1
|
sphingosine-1-phosphate receptor 1 |
| chr12_+_11905413 | 0.85 |
ENST00000545027.1
|
ETV6
|
ets variant 6 |
| chr10_+_95256356 | 0.84 |
ENST00000371485.3
|
CEP55
|
centrosomal protein 55kDa |
| chr19_-_17958771 | 0.84 |
ENST00000534444.1
|
JAK3
|
Janus kinase 3 |
| chr11_-_28129656 | 0.84 |
ENST00000263181.6
|
KIF18A
|
kinesin family member 18A |
| chr19_-_45748628 | 0.84 |
ENST00000590022.1
|
AC006126.4
|
AC006126.4 |
| chr5_-_137610300 | 0.83 |
ENST00000274721.3
|
GFRA3
|
GDNF family receptor alpha 3 |
| chr12_-_49318715 | 0.82 |
ENST00000444214.2
|
FKBP11
|
FK506 binding protein 11, 19 kDa |
| chr20_-_44516256 | 0.81 |
ENST00000372519.3
|
SPATA25
|
spermatogenesis associated 25 |
| chr12_+_52430894 | 0.81 |
ENST00000546842.1
|
NR4A1
|
nuclear receptor subfamily 4, group A, member 1 |
| chr7_-_36764004 | 0.80 |
ENST00000431169.1
|
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr16_-_67450325 | 0.80 |
ENST00000348579.2
|
ZDHHC1
|
zinc finger, DHHC-type containing 1 |
| chr14_+_21249200 | 0.79 |
ENST00000304677.2
|
RNASE6
|
ribonuclease, RNase A family, k6 |
| chr12_+_65672423 | 0.79 |
ENST00000355192.3
ENST00000308259.5 ENST00000540804.1 ENST00000535664.1 ENST00000541189.1 |
MSRB3
|
methionine sulfoxide reductase B3 |
| chr19_+_55281260 | 0.79 |
ENST00000336077.6
ENST00000291633.7 |
KIR2DL1
|
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| chr12_+_54379569 | 0.78 |
ENST00000513209.1
|
RP11-834C11.12
|
RP11-834C11.12 |
| chr11_+_71846764 | 0.77 |
ENST00000456237.1
ENST00000442948.2 ENST00000546166.1 |
FOLR3
|
folate receptor 3 (gamma) |
| chr5_-_137610254 | 0.77 |
ENST00000378362.3
|
GFRA3
|
GDNF family receptor alpha 3 |
| chr19_+_50529212 | 0.77 |
ENST00000270617.3
ENST00000445728.3 ENST00000601364.1 |
ZNF473
|
zinc finger protein 473 |
| chr11_-_66112555 | 0.77 |
ENST00000425825.2
ENST00000359957.3 |
BRMS1
|
breast cancer metastasis suppressor 1 |
| chr14_+_95027772 | 0.76 |
ENST00000555095.1
ENST00000298841.5 ENST00000554220.1 ENST00000553780.1 |
SERPINA4
SERPINA5
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| chr12_+_65672702 | 0.76 |
ENST00000538045.1
ENST00000535239.1 |
MSRB3
|
methionine sulfoxide reductase B3 |
| chr4_+_141445333 | 0.76 |
ENST00000507667.1
|
ELMOD2
|
ELMO/CED-12 domain containing 2 |
| chr1_+_178482212 | 0.76 |
ENST00000319416.2
ENST00000258298.2 ENST00000367643.3 ENST00000367642.3 |
TEX35
|
testis expressed 35 |
| chr11_-_615570 | 0.75 |
ENST00000525445.1
ENST00000348655.6 ENST00000397566.1 |
IRF7
|
interferon regulatory factor 7 |
| chr6_-_84937314 | 0.75 |
ENST00000257766.4
ENST00000403245.3 |
KIAA1009
|
KIAA1009 |
| chr11_+_120081475 | 0.75 |
ENST00000328965.4
|
OAF
|
OAF homolog (Drosophila) |
| chr19_-_40772221 | 0.75 |
ENST00000441941.2
ENST00000580747.1 |
AKT2
|
v-akt murine thymoma viral oncogene homolog 2 |
| chr1_+_172628154 | 0.75 |
ENST00000340030.3
ENST00000367721.2 |
FASLG
|
Fas ligand (TNF superfamily, member 6) |
| chr19_+_50528971 | 0.74 |
ENST00000598809.1
ENST00000595661.1 ENST00000391821.2 |
ZNF473
|
zinc finger protein 473 |
| chr11_+_1940786 | 0.73 |
ENST00000278317.6
ENST00000381561.4 ENST00000381548.3 ENST00000360603.3 ENST00000381549.3 |
TNNT3
|
troponin T type 3 (skeletal, fast) |
| chr6_-_26108355 | 0.73 |
ENST00000338379.4
|
HIST1H1T
|
histone cluster 1, H1t |
| chr12_+_57853918 | 0.73 |
ENST00000532291.1
ENST00000543426.1 ENST00000228682.2 ENST00000546141.1 |
GLI1
|
GLI family zinc finger 1 |
| chr1_+_206858232 | 0.72 |
ENST00000294981.4
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2 |
| chr1_-_1141927 | 0.71 |
ENST00000328596.6
ENST00000379265.5 |
TNFRSF18
|
tumor necrosis factor receptor superfamily, member 18 |
| chr9_-_134585221 | 0.70 |
ENST00000372190.3
ENST00000427994.1 |
RAPGEF1
|
Rap guanine nucleotide exchange factor (GEF) 1 |
| chr20_+_48884002 | 0.70 |
ENST00000425497.1
ENST00000445003.1 |
RP11-290F20.3
|
RP11-290F20.3 |
| chr16_+_27413483 | 0.69 |
ENST00000337929.3
ENST00000564089.1 |
IL21R
|
interleukin 21 receptor |
| chr19_-_44174330 | 0.69 |
ENST00000340093.3
|
PLAUR
|
plasminogen activator, urokinase receptor |
| chr4_+_55096010 | 0.69 |
ENST00000503856.1
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide |
| chr7_-_36764142 | 0.69 |
ENST00000258749.5
ENST00000535891.1 |
AOAH
|
acyloxyacyl hydrolase (neutrophil) |
| chr20_+_59654146 | 0.69 |
ENST00000441660.1
|
RP5-827L5.1
|
RP5-827L5.1 |
| chr2_+_53994927 | 0.68 |
ENST00000295304.4
|
CHAC2
|
ChaC, cation transport regulator homolog 2 (E. coli) |
| chr2_+_28718921 | 0.68 |
ENST00000327757.5
ENST00000422425.2 ENST00000404858.1 |
PLB1
|
phospholipase B1 |
| chr9_+_214842 | 0.68 |
ENST00000453981.1
ENST00000432829.2 |
DOCK8
|
dedicator of cytokinesis 8 |
| chr22_+_35776828 | 0.67 |
ENST00000216117.8
|
HMOX1
|
heme oxygenase (decycling) 1 |
| chr3_-_187694195 | 0.67 |
ENST00000446091.1
|
RP11-132N15.3
|
RP11-132N15.3 |
| chr19_-_13213662 | 0.67 |
ENST00000264824.4
|
LYL1
|
lymphoblastic leukemia derived sequence 1 |
| chr17_-_7590745 | 0.66 |
ENST00000514944.1
ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4 |
TP53
|
tumor protein p53 |
| chr12_+_75874984 | 0.66 |
ENST00000550491.1
|
GLIPR1
|
GLI pathogenesis-related 1 |
| chr2_+_102758210 | 0.65 |
ENST00000450319.1
|
IL1R1
|
interleukin 1 receptor, type I |
| chr4_+_55096489 | 0.65 |
ENST00000504461.1
|
PDGFRA
|
platelet-derived growth factor receptor, alpha polypeptide |
| chr22_+_24823517 | 0.65 |
ENST00000496258.1
ENST00000337539.7 |
ADORA2A
|
adenosine A2a receptor |
| chr9_-_96717654 | 0.65 |
ENST00000253968.6
|
BARX1
|
BARX homeobox 1 |
| chr22_+_22988816 | 0.65 |
ENST00000480559.1
ENST00000448514.1 |
GGTLC2
|
gamma-glutamyltransferase light chain 2 |
| chr2_+_90248739 | 0.65 |
ENST00000468879.1
|
IGKV1D-43
|
immunoglobulin kappa variable 1D-43 |
| chr2_+_102758271 | 0.64 |
ENST00000428279.1
|
IL1R1
|
interleukin 1 receptor, type I |
| chr4_+_105828537 | 0.64 |
ENST00000515649.1
|
RP11-556I14.1
|
RP11-556I14.1 |
| chr1_+_182758900 | 0.64 |
ENST00000367555.1
ENST00000367554.3 |
NPL
|
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| chr6_-_31619697 | 0.64 |
ENST00000434444.1
|
BAG6
|
BCL2-associated athanogene 6 |
| chr6_-_31620149 | 0.64 |
ENST00000435080.1
ENST00000375976.4 ENST00000441054.1 |
BAG6
|
BCL2-associated athanogene 6 |
| chr3_-_183967296 | 0.64 |
ENST00000455059.1
ENST00000445626.2 |
ALG3
|
ALG3, alpha-1,3- mannosyltransferase |
| chr12_-_56121580 | 0.64 |
ENST00000550776.1
|
CD63
|
CD63 molecule |
| chr8_+_24241969 | 0.63 |
ENST00000522298.1
|
ADAMDEC1
|
ADAM-like, decysin 1 |
| chr20_-_23433494 | 0.63 |
ENST00000377007.3
|
CST11
|
cystatin 11 |
| chr9_-_71161505 | 0.63 |
ENST00000446290.1
|
RP11-274B18.2
|
RP11-274B18.2 |
| chr6_-_130536774 | 0.63 |
ENST00000532763.1
|
SAMD3
|
sterile alpha motif domain containing 3 |
| chr10_-_74114714 | 0.62 |
ENST00000338820.3
ENST00000394903.2 ENST00000444643.2 |
DNAJB12
|
DnaJ (Hsp40) homolog, subfamily B, member 12 |
| chr1_-_67519782 | 0.62 |
ENST00000235345.5
|
SLC35D1
|
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| chr1_+_92417716 | 0.61 |
ENST00000402388.1
|
BRDT
|
bromodomain, testis-specific |
| chr12_-_15104040 | 0.61 |
ENST00000541644.1
ENST00000545895.1 |
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta |
| chrX_-_119693745 | 0.61 |
ENST00000371323.2
|
CUL4B
|
cullin 4B |
| chr5_-_44388899 | 0.61 |
ENST00000264664.4
|
FGF10
|
fibroblast growth factor 10 |
| chr3_-_119379427 | 0.61 |
ENST00000264231.3
ENST00000468801.1 ENST00000538678.1 |
POPDC2
|
popeye domain containing 2 |
| chrX_-_53461288 | 0.60 |
ENST00000375298.4
ENST00000375304.5 |
HSD17B10
|
hydroxysteroid (17-beta) dehydrogenase 10 |
| chr19_+_18529674 | 0.60 |
ENST00000597724.2
|
SSBP4
|
single stranded DNA binding protein 4 |
| chr17_-_43502987 | 0.60 |
ENST00000376922.2
|
ARHGAP27
|
Rho GTPase activating protein 27 |
| chr6_-_160166218 | 0.59 |
ENST00000537657.1
|
SOD2
|
superoxide dismutase 2, mitochondrial |
| chr19_-_46526304 | 0.59 |
ENST00000008938.4
|
PGLYRP1
|
peptidoglycan recognition protein 1 |
| chr5_+_110407390 | 0.59 |
ENST00000344895.3
|
TSLP
|
thymic stromal lymphopoietin |
| chr20_+_816695 | 0.59 |
ENST00000246100.3
|
FAM110A
|
family with sequence similarity 110, member A |
| chr11_-_15643937 | 0.59 |
ENST00000533082.1
|
RP11-531H8.2
|
RP11-531H8.2 |
| chr12_-_56122426 | 0.59 |
ENST00000551173.1
|
CD63
|
CD63 molecule |
| chr2_+_29033682 | 0.59 |
ENST00000379579.4
ENST00000334056.5 ENST00000449210.1 |
SPDYA
|
speedy/RINGO cell cycle regulator family member A |
| chr19_-_55458860 | 0.59 |
ENST00000592784.1
ENST00000448121.2 ENST00000340844.2 |
NLRP7
|
NLR family, pyrin domain containing 7 |
| chr10_-_97175444 | 0.59 |
ENST00000486141.2
|
SORBS1
|
sorbin and SH3 domain containing 1 |
| chr12_-_53614043 | 0.59 |
ENST00000338561.5
|
RARG
|
retinoic acid receptor, gamma |
| chr16_-_11367452 | 0.58 |
ENST00000327157.2
|
PRM3
|
protamine 3 |
| chr19_-_50529193 | 0.58 |
ENST00000596445.1
ENST00000599538.1 |
VRK3
|
vaccinia related kinase 3 |
| chr12_-_46385811 | 0.58 |
ENST00000419565.2
|
SCAF11
|
SR-related CTD-associated factor 11 |
| chr12_+_21525818 | 0.58 |
ENST00000240652.3
ENST00000542023.1 ENST00000537593.1 |
IAPP
|
islet amyloid polypeptide |
| chr8_+_56014949 | 0.58 |
ENST00000327381.6
|
XKR4
|
XK, Kell blood group complex subunit-related family, member 4 |
| chr22_-_31328881 | 0.58 |
ENST00000445980.1
|
MORC2
|
MORC family CW-type zinc finger 2 |
| chr12_-_18890940 | 0.57 |
ENST00000543242.1
ENST00000539072.1 ENST00000541966.1 ENST00000266505.7 ENST00000447925.2 ENST00000435379.1 |
PLCZ1
|
phospholipase C, zeta 1 |
| chr21_-_35884573 | 0.57 |
ENST00000399286.2
|
KCNE1
|
potassium voltage-gated channel, Isk-related family, member 1 |
| chr15_-_37783009 | 0.57 |
ENST00000561054.1
|
RP11-720L8.1
|
RP11-720L8.1 |
| chr3_-_39196049 | 0.57 |
ENST00000514182.1
|
CSRNP1
|
cysteine-serine-rich nuclear protein 1 |
| chr20_+_44509857 | 0.56 |
ENST00000372523.1
ENST00000372520.1 |
ZSWIM1
|
zinc finger, SWIM-type containing 1 |
| chr19_-_17958832 | 0.56 |
ENST00000458235.1
|
JAK3
|
Janus kinase 3 |
| chr12_-_57522813 | 0.56 |
ENST00000556155.1
|
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr11_-_44972476 | 0.56 |
ENST00000527685.1
ENST00000308212.5 |
TP53I11
|
tumor protein p53 inducible protein 11 |
| chr19_+_50832943 | 0.55 |
ENST00000542413.1
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2 |
| chr14_-_51411194 | 0.55 |
ENST00000544180.2
|
PYGL
|
phosphorylase, glycogen, liver |
| chr7_+_99036996 | 0.54 |
ENST00000441580.1
ENST00000412686.1 |
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa |
| chr19_+_55897699 | 0.54 |
ENST00000558131.1
ENST00000558752.1 ENST00000458349.2 |
RPL28
|
ribosomal protein L28 |
| chr8_-_134584092 | 0.54 |
ENST00000522652.1
|
ST3GAL1
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| chr1_-_6260896 | 0.54 |
ENST00000497965.1
|
RPL22
|
ribosomal protein L22 |
| chr2_-_209118974 | 0.54 |
ENST00000415913.1
ENST00000415282.1 ENST00000446179.1 |
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.7 | GO:0038112 | interleukin-8-mediated signaling pathway(GO:0038112) |
| 0.6 | 2.8 | GO:0090467 | L-arginine import(GO:0043091) arginine import(GO:0090467) |
| 0.5 | 2.1 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.5 | 1.4 | GO:0045082 | positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.5 | 1.4 | GO:0045210 | negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) |
| 0.5 | 2.8 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.4 | 1.4 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.3 | 1.3 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.3 | 1.9 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 0.3 | 1.6 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.3 | 0.9 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 0.3 | 0.8 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.3 | 1.1 | GO:0060032 | notochord regression(GO:0060032) |
| 0.3 | 0.3 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.3 | 2.6 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.2 | 3.2 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.2 | 1.6 | GO:0070384 | Harderian gland development(GO:0070384) |
| 0.2 | 0.7 | GO:0061485 | memory T cell proliferation(GO:0061485) |
| 0.2 | 1.3 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.2 | 0.7 | GO:0090108 | positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340) |
| 0.2 | 0.9 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 0.2 | 1.1 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.2 | 0.6 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.2 | 5.0 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 1.2 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.2 | 0.6 | GO:0032824 | negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714) |
| 0.2 | 1.8 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
| 0.2 | 2.0 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.2 | 1.3 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.2 | 1.3 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) |
| 0.2 | 2.0 | GO:0035771 | interleukin-4-mediated signaling pathway(GO:0035771) |
| 0.2 | 0.5 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.2 | 0.5 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 0.2 | 0.9 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.2 | 0.7 | GO:0006788 | heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) |
| 0.2 | 0.7 | GO:0051097 | negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252) |
| 0.2 | 2.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.2 | 1.1 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
| 0.2 | 0.5 | GO:0042231 | interleukin-13 biosynthetic process(GO:0042231) |
| 0.1 | 1.5 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 0.9 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.1 | 1.1 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.1 | 1.0 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 1.0 | GO:0097473 | cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.1 | 1.5 | GO:0070543 | response to linoleic acid(GO:0070543) |
| 0.1 | 1.8 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.1 | 0.9 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 0.1 | 3.0 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.1 | 1.1 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.8 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.1 | 0.6 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.1 | 0.9 | GO:0050955 | thermoception(GO:0050955) |
| 0.1 | 0.7 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.1 | 0.5 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 0.1 | 0.9 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.1 | 0.2 | GO:0046110 | xanthine metabolic process(GO:0046110) |
| 0.1 | 1.6 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 0.6 | GO:0003069 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.1 | 1.0 | GO:2000510 | positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 0.1 | 0.6 | GO:0007343 | egg activation(GO:0007343) |
| 0.1 | 0.3 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.1 | 0.8 | GO:0002767 | immune response-inhibiting cell surface receptor signaling pathway(GO:0002767) |
| 0.1 | 0.9 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.1 | 0.6 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.1 | 3.6 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.5 | GO:0046778 | modification by virus of host mRNA processing(GO:0046778) |
| 0.1 | 0.5 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.1 | 0.8 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 0.3 | GO:0002372 | myeloid dendritic cell cytokine production(GO:0002372) |
| 0.1 | 0.4 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.1 | 1.5 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.1 | 0.7 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.1 | 2.3 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.1 | 1.1 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
| 0.1 | 0.4 | GO:1902024 | histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024) |
| 0.1 | 0.4 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.1 | 0.7 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
| 0.1 | 0.6 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.1 | 0.5 | GO:0039019 | pronephric nephron development(GO:0039019) |
| 0.1 | 0.4 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 0.3 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.1 | 0.2 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.1 | 0.7 | GO:0071395 | response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395) |
| 0.1 | 1.0 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.1 | 1.6 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.1 | 0.2 | GO:1903464 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.1 | 0.6 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.1 | 0.4 | GO:0010847 | regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 0.3 | GO:0098838 | reduced folate transmembrane transport(GO:0098838) |
| 0.1 | 0.8 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.1 | 0.5 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.1 | 0.2 | GO:0061580 | colon epithelial cell migration(GO:0061580) |
| 0.1 | 0.3 | GO:2001162 | regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162) |
| 0.1 | 0.4 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 1.6 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.1 | 0.4 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 1.6 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 0.8 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 0.8 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.1 | 0.3 | GO:0061687 | detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) |
| 0.1 | 1.7 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.1 | 0.5 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.1 | 0.1 | GO:0060268 | negative regulation of respiratory burst(GO:0060268) |
| 0.1 | 0.6 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.1 | 1.0 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.1 | 0.8 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.1 | 0.6 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.1 | 0.5 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.1 | 0.3 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 0.1 | 0.3 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.1 | 0.3 | GO:0001519 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 0.1 | 0.8 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.1 | 1.0 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 2.0 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.1 | 2.4 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.1 | 0.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.1 | 0.3 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.1 | 0.4 | GO:1901297 | arterial endothelial cell fate commitment(GO:0060844) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.1 | 0.2 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 8.4 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 0.7 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.1 | 0.9 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 0.4 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.0 | 0.5 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 1.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 1.7 | GO:0045589 | regulation of regulatory T cell differentiation(GO:0045589) |
| 0.0 | 0.2 | GO:0009107 | lipoate biosynthetic process(GO:0009107) |
| 0.0 | 0.7 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.0 | 0.4 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.0 | 1.1 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.0 | 0.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.0 | 0.2 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 0.0 | 0.4 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.0 | 1.3 | GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
| 0.0 | 0.5 | GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.7 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.3 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.0 | 0.6 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 0.0 | 0.5 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.9 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.2 | GO:0021827 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.0 | 3.2 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.4 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.0 | 0.7 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 1.4 | GO:0048485 | sympathetic nervous system development(GO:0048485) |
| 0.0 | 0.2 | GO:0061083 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.0 | 0.9 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.0 | 0.1 | GO:0071393 | cellular response to progesterone stimulus(GO:0071393) |
| 0.0 | 0.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.0 | 0.1 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.0 | 0.5 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.0 | 0.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 0.4 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.2 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.0 | 0.1 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.0 | 0.3 | GO:1902846 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.0 | 0.2 | GO:2000323 | circadian regulation of translation(GO:0097167) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.0 | 0.7 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.0 | 0.6 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.0 | 0.3 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.5 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.0 | 0.4 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.0 | 0.1 | GO:0003415 | chondrocyte hypertrophy(GO:0003415) |
| 0.0 | 0.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.0 | 0.6 | GO:0071474 | cellular hyperosmotic response(GO:0071474) |
| 0.0 | 0.1 | GO:0097017 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) renal protein absorption(GO:0097017) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.0 | 0.1 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.0 | 0.4 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.0 | 0.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.0 | 2.2 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
| 0.0 | 0.4 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.0 | 1.8 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.4 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.0 | 0.4 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.1 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
| 0.0 | 0.4 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) |
| 0.0 | 0.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.1 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 0.4 | GO:0033630 | positive regulation of cell adhesion mediated by integrin(GO:0033630) |
| 0.0 | 0.6 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.0 | 0.5 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 0.2 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
| 0.0 | 0.9 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.4 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.0 | 0.6 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 1.1 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.0 | 0.2 | GO:0055009 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
| 0.0 | 0.5 | GO:0060397 | JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) |
| 0.0 | 0.7 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.6 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.0 | 0.4 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.0 | 0.3 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
| 0.0 | 0.9 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.5 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 0.9 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.3 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.0 | 0.5 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 1.3 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.2 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.0 | 0.4 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.4 | GO:0034384 | high-density lipoprotein particle clearance(GO:0034384) |
| 0.0 | 0.6 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.2 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.0 | 0.6 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
| 0.0 | 0.5 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.4 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.4 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.7 | GO:0048536 | spleen development(GO:0048536) |
| 0.0 | 0.3 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.0 | 0.1 | GO:0061101 | neuroendocrine cell differentiation(GO:0061101) |
| 0.0 | 0.2 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.0 | 0.2 | GO:2000507 | cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507) |
| 0.0 | 0.5 | GO:0006631 | fatty acid metabolic process(GO:0006631) |
| 0.0 | 0.5 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 0.1 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.4 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.0 | 0.6 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.3 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.1 | GO:0009149 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 0.0 | 0.3 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.6 | GO:0044364 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) |
| 0.0 | 0.3 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 0.4 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.0 | 0.1 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205) |
| 0.0 | 0.4 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.0 | 0.6 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.0 | 0.2 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.4 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.1 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
| 0.0 | 0.3 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.3 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 0.7 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.3 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.2 | 3.2 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.2 | 2.6 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.2 | 1.5 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.2 | 0.8 | GO:0097183 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.2 | 2.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 2.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 1.1 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.1 | 1.0 | GO:0034688 | integrin alphaM-beta2 complex(GO:0034688) |
| 0.1 | 0.3 | GO:0036194 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 0.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.1 | 7.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 3.0 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 0.6 | GO:0097013 | phagocytic vesicle lumen(GO:0097013) |
| 0.1 | 0.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.1 | 0.9 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 0.2 | GO:0005668 | RNA polymerase transcription factor SL1 complex(GO:0005668) |
| 0.1 | 0.5 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 0.1 | 0.8 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.9 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 0.2 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.1 | 0.3 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.1 | 0.8 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 0.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 1.1 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.1 | 0.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 1.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 0.8 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.7 | GO:0043197 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
| 0.0 | 1.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.5 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.8 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 5.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.8 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.4 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 0.4 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.0 | 0.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.4 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 0.1 | GO:0034515 | proteasome storage granule(GO:0034515) |
| 0.0 | 0.4 | GO:0005638 | lamin filament(GO:0005638) |
| 0.0 | 0.3 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.0 | 0.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.5 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 1.6 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.0 | 1.8 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.8 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 3.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.4 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.3 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.4 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
| 0.0 | 0.4 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.5 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.1 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.3 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 9.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.2 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.0 | 0.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 2.1 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.3 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.5 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.5 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 3.6 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 1.1 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.8 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 0.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.1 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.0 | 0.9 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.0 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 1.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.6 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 0.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.6 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 0.4 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.9 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.8 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 2.0 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.1 | GO:0044754 | autolysosome(GO:0044754) |
| 0.0 | 0.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 1.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.3 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.3 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.5 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.6 | 3.7 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.6 | 2.4 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
| 0.5 | 1.4 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.4 | 2.8 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.3 | 3.0 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.3 | 1.3 | GO:0005018 | platelet-derived growth factor alpha-receptor activity(GO:0005018) |
| 0.2 | 1.6 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.2 | 0.7 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
| 0.2 | 0.9 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.2 | 0.9 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.2 | 0.6 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.2 | 1.1 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) |
| 0.2 | 1.5 | GO:0005124 | N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124) |
| 0.2 | 0.6 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.2 | 0.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325) |
| 0.2 | 0.7 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
| 0.2 | 0.5 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.2 | 1.8 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 0.7 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.2 | 0.7 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.2 | 0.5 | GO:0035034 | histone acetyltransferase regulator activity(GO:0035034) |
| 0.2 | 1.1 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 0.2 | 0.6 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.1 | 0.6 | GO:0008745 | N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) |
| 0.1 | 0.4 | GO:0051139 | metal ion:proton antiporter activity(GO:0051139) |
| 0.1 | 0.4 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
| 0.1 | 1.0 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 3.6 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.5 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 0.5 | GO:0008184 | purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184) |
| 0.1 | 0.7 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
| 0.1 | 1.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.1 | 0.4 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 0.1 | 2.0 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.1 | 0.5 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.1 | 1.0 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 2.6 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.1 | 1.0 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 0.5 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.1 | 0.5 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.1 | 0.6 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 0.6 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.1 | 0.7 | GO:0047086 | phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086) |
| 0.1 | 0.6 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.1 | 0.3 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.1 | 0.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 2.4 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 0.5 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) |
| 0.1 | 0.3 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.1 | 0.5 | GO:0047685 | amine sulfotransferase activity(GO:0047685) |
| 0.1 | 0.3 | GO:0004307 | diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307) |
| 0.1 | 1.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 0.3 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.1 | 0.3 | GO:0008518 | reduced folate carrier activity(GO:0008518) |
| 0.1 | 6.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 1.0 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 0.1 | 1.1 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
| 0.1 | 1.0 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.1 | 0.2 | GO:0005148 | prolactin receptor binding(GO:0005148) |
| 0.1 | 0.6 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 0.3 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.1 | 0.4 | GO:1901474 | azole transmembrane transporter activity(GO:1901474) |
| 0.1 | 0.8 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 2.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.2 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.1 | 0.5 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.2 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
| 0.1 | 0.3 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 0.1 | 0.4 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 1.0 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 0.5 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 0.5 | GO:0030884 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.1 | 0.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.7 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 1.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.7 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 1.0 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.0 | 0.6 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 0.8 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.9 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.4 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.0 | 1.9 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 0.2 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.0 | 0.1 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.0 | 1.0 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.7 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 1.7 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 1.5 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.2 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 0.0 | 0.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 1.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.5 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.0 | 0.3 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 1.5 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.1 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.9 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.1 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.0 | 1.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 2.0 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.2 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.0 | 0.8 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.0 | 0.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.0 | 0.4 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 1.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.7 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.0 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 0.9 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 2.6 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 1.6 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 0.4 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.0 | 0.3 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.2 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.0 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.1 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
| 0.0 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 1.7 | GO:0016279 | protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.1 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.0 | 0.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 1.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.6 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 2.2 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 1.4 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 2.5 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.0 | 9.8 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 0.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.2 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 0.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.4 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.0 | 4.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.2 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
| 0.0 | 0.8 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 1.3 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 3.3 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.0 | 0.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 1.4 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.1 | 3.7 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 5.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 4.5 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 0.4 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 2.0 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 3.4 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.6 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 2.7 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 3.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 3.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 3.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.9 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.8 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.7 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 4.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.2 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 1.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.2 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.3 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 1.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 3.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.3 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.4 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.6 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.5 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 5.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.3 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.3 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.1 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 5.0 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.1 | 3.2 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.1 | 2.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 4.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.1 | 1.5 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 1.1 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 6.7 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 2.8 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 1.6 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 0.3 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 1.0 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 0.7 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 0.7 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 3.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.9 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 1.6 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 2.5 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.9 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.2 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.0 | 1.8 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.6 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 2.8 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 1.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.7 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.2 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 3.3 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.0 | 1.3 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 1.2 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.3 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 0.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.5 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.6 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.8 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.0 | 2.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.2 | REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT | Genes involved in p53-Independent G1/S DNA damage checkpoint |
| 0.0 | 0.6 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.6 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.2 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 2.1 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 1.9 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.7 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.0 | 2.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.4 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.1 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.4 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 1.9 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.3 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 1.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.5 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.5 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 2.6 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.9 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 0.7 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 1.0 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 0.7 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |