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Illumina Body Map 2, young vs old

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Results for TBX3

Z-value: 0.86

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
TBX3
ENSG00000135111.10 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg19_v2_chr12_-_115121962_115121987-0.086.8e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_156824840 4.44 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr6_-_52668605 3.83 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr20_+_56725952 3.73 ENST00000371168.3
C20orf85
chromosome 20 open reading frame 85
chr13_-_46679144 3.43 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr22_+_22749343 3.26 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr2_-_89310012 3.18 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr5_+_54320078 3.00 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr14_-_106642049 2.98 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr3_+_149192475 2.93 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr22_+_23237555 2.90 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr2_-_89266286 2.88 ENST00000464162.1
IGKV1-6
immunoglobulin kappa variable 1-6
chr14_-_106471723 2.73 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr16_+_72088376 2.72 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr14_+_22475742 2.63 ENST00000390447.3
TRAV19
T cell receptor alpha variable 19
chr2_-_89513402 2.49 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr2_+_90229045 2.48 ENST00000390278.2
IGKV1D-42
immunoglobulin kappa variable 1D-42 (non-functional)
chr3_+_149191723 2.36 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr22_+_23063100 2.35 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr4_+_155484155 2.24 ENST00000509493.1
FGB
fibrinogen beta chain
chr14_-_94919103 2.16 ENST00000334708.3
SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr4_+_40195262 2.14 ENST00000503941.1
RHOH
ras homolog family member H
chr11_-_18258342 2.12 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr2_+_241807870 2.09 ENST00000307503.3
AGXT
alanine-glyoxylate aminotransferase
chr4_+_155484103 2.08 ENST00000302068.4
FGB
fibrinogen beta chain
chr17_-_7017559 1.99 ENST00000446679.2
ASGR2
asialoglycoprotein receptor 2
chr14_-_107283278 1.91 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr4_-_71532207 1.87 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_+_142448053 1.86 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr3_+_108541545 1.83 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr2_+_89184868 1.82 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr4_-_84030996 1.77 ENST00000411416.2
PLAC8
placenta-specific 8
chr6_-_52628271 1.73 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr2_+_90153696 1.70 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr3_+_108541608 1.65 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_+_22433675 1.63 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr15_+_38296918 1.63 ENST00000557883.2
RP11-1008C21.1
RP11-1008C21.1
chr2_+_90259593 1.61 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr2_+_90192768 1.59 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr22_+_22723969 1.57 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr5_-_80689945 1.56 ENST00000307624.3
ACOT12
acyl-CoA thioesterase 12
chr2_-_209118974 1.54 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr2_+_96331830 1.49 ENST00000425887.2
AC008268.1
AC008268.1
chr12_+_11081828 1.48 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr2_-_89545079 1.45 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr11_-_104893863 1.45 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr19_-_3478477 1.41 ENST00000591708.1
C19orf77
chromosome 19 open reading frame 77
chr1_+_159772121 1.36 ENST00000339348.5
ENST00000392235.3
ENST00000368106.3
FCRL6
Fc receptor-like 6
chr7_-_99381884 1.34 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chrX_-_131623043 1.33 ENST00000421707.1
MBNL3
muscleblind-like splicing regulator 3
chr9_-_113100088 1.33 ENST00000374510.4
ENST00000423740.2
ENST00000374511.3
ENST00000374507.4
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr19_-_33360647 1.33 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr11_+_7506837 1.32 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr3_+_52454971 1.30 ENST00000465863.1
PHF7
PHD finger protein 7
chr3_-_42452050 1.28 ENST00000441172.1
ENST00000287748.3
LYZL4
lysozyme-like 4
chrX_+_73524020 1.24 ENST00000339534.2
ZCCHC13
zinc finger, CCHC domain containing 13
chr10_+_71561704 1.24 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr1_+_94798754 1.23 ENST00000418242.1
RP11-148B18.3
RP11-148B18.3
chr20_+_29956369 1.23 ENST00000253381.2
DEFB118
defensin, beta 118
chr21_-_15918618 1.22 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_212208919 1.21 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr22_+_24999114 1.19 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr2_-_209119831 1.17 ENST00000345146.2
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr19_-_51530916 1.17 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr17_-_55822653 1.15 ENST00000299415.2
AC007431.1
coiled-coil domain containing 182
chr4_+_187148556 1.14 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr2_-_133429091 1.13 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr1_+_162351503 1.13 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr2_+_234580499 1.11 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr10_+_71561630 1.11 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr19_-_51531272 1.11 ENST00000319720.7
KLK11
kallikrein-related peptidase 11
chr11_-_104916034 1.09 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr19_-_52005009 1.08 ENST00000291707.3
SIGLEC12
sialic acid binding Ig-like lectin 12 (gene/pseudogene)
chr1_+_172628154 1.06 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr2_-_4021609 1.06 ENST00000425949.1
ENST00000453880.1
ENST00000588796.1
AC107070.1
AC107070.1
chr19_+_1077393 1.05 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr4_+_15704573 1.05 ENST00000265016.4
BST1
bone marrow stromal cell antigen 1
chr11_+_7506713 1.05 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr6_+_126661253 1.04 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW
centromere protein W
chr7_-_99381798 1.02 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr6_-_32821599 1.01 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr22_+_24891210 1.00 ENST00000382760.2
UPB1
ureidopropionase, beta
chr6_+_160542821 1.00 ENST00000366963.4
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chr19_-_7766991 0.98 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr1_+_159770292 0.98 ENST00000536257.1
ENST00000321935.6
FCRL6
Fc receptor-like 6
chr20_+_55108302 0.98 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr2_+_234580525 0.98 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_+_22766766 0.98 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_182921119 0.97 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr11_+_45743858 0.97 ENST00000532307.1
CTD-2210P24.1
CTD-2210P24.1
chrX_+_150884539 0.96 ENST00000417321.1
FATE1
fetal and adult testis expressed 1
chr4_-_46911223 0.96 ENST00000396533.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr16_+_27078219 0.94 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chrX_-_101726732 0.93 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
NXF2B
TCP11X2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2
chr7_-_93519471 0.93 ENST00000451238.1
TFPI2
tissue factor pathway inhibitor 2
chr14_+_24641820 0.93 ENST00000560501.1
REC8
REC8 meiotic recombination protein
chr19_-_51531210 0.92 ENST00000391804.3
KLK11
kallikrein-related peptidase 11
chr14_-_21056121 0.92 ENST00000557105.1
ENST00000398008.2
ENST00000555841.1
ENST00000443456.2
ENST00000432835.2
ENST00000557503.1
ENST00000398009.2
ENST00000554842.1
RNASE11
ribonuclease, RNase A family, 11 (non-active)
chr7_+_137761199 0.92 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr12_+_7169887 0.90 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr21_-_46340807 0.90 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_60883993 0.90 ENST00000583803.1
ENST00000456609.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr11_+_34643600 0.90 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr17_-_3375033 0.90 ENST00000268981.5
ENST00000397168.3
ENST00000572969.1
ENST00000355380.4
ENST00000571553.1
ENST00000574797.1
ENST00000575375.1
SPATA22
spermatogenesis associated 22
chr6_+_32821924 0.89 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr3_+_133118839 0.89 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr10_+_71561649 0.87 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chrX_+_101470280 0.86 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2
TCP11X1
nuclear RNA export factor 2
t-complex 11 family, X-linked 1
chr12_+_12223867 0.85 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chr12_+_57849048 0.85 ENST00000266646.2
INHBE
inhibin, beta E
chr17_+_45286387 0.85 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr11_+_77774897 0.84 ENST00000281030.2
THRSP
thyroid hormone responsive
chrX_-_70838306 0.84 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chr7_+_117119187 0.84 ENST00000446805.1
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_+_94713418 0.83 ENST00000413103.1
RP11-148B18.1
RP11-148B18.1
chr2_-_4021643 0.82 ENST00000454455.1
AC107070.1
AC107070.1
chr11_-_10590118 0.81 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr17_+_20483037 0.79 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr10_-_44274273 0.79 ENST00000419406.1
RP11-272J7.4
RP11-272J7.4
chr19_-_51538148 0.79 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr11_+_18433840 0.76 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr15_-_50411412 0.76 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr11_-_327537 0.75 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr2_+_149974684 0.74 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr4_+_123300664 0.74 ENST00000388725.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr2_+_234637754 0.73 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_-_121825088 0.72 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr19_+_9361606 0.72 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr10_+_90750378 0.71 ENST00000355740.2
ENST00000352159.4
FAS
Fas cell surface death receptor
chr11_-_10590238 0.70 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr6_+_6588316 0.70 ENST00000379953.2
LY86
lymphocyte antigen 86
chr2_+_202937972 0.69 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr20_+_123010 0.69 ENST00000382398.3
DEFB126
defensin, beta 126
chr16_+_63764128 0.68 ENST00000563061.1
RP11-370P15.2
RP11-370P15.2
chr3_-_172019686 0.68 ENST00000596321.1
AC092964.2
Uncharacterized protein
chr9_-_100954910 0.68 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr14_+_90422867 0.67 ENST00000553989.1
TDP1
tyrosyl-DNA phosphodiesterase 1
chr15_-_38852251 0.66 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr11_+_45743931 0.66 ENST00000530051.1
CTD-2210P24.1
CTD-2210P24.1
chr12_-_7848364 0.66 ENST00000329913.3
GDF3
growth differentiation factor 3
chr2_-_55459485 0.66 ENST00000451916.1
CLHC1
clathrin heavy chain linker domain containing 1
chr20_+_2795626 0.65 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr9_+_273038 0.64 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr20_-_1472053 0.64 ENST00000537284.1
SIRPB2
signal-regulatory protein beta 2
chr16_-_67360662 0.63 ENST00000304372.5
KCTD19
potassium channel tetramerization domain containing 19
chrX_-_131352152 0.62 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr4_-_80247162 0.62 ENST00000286794.4
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr1_-_89488510 0.62 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr11_-_104972158 0.62 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_+_151020175 0.61 ENST00000368926.5
C1orf56
chromosome 1 open reading frame 56
chr8_+_23386305 0.60 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr19_-_43835582 0.60 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr2_+_162101247 0.58 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr7_+_150434430 0.58 ENST00000358647.3
GIMAP5
GTPase, IMAP family member 5
chr2_-_37415690 0.57 ENST00000260637.3
ENST00000535679.1
ENST00000379149.2
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr1_-_183560011 0.57 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr4_-_46911248 0.56 ENST00000355591.3
ENST00000505102.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr12_+_1800179 0.56 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chrX_+_44703249 0.55 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr19_+_41103063 0.55 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr19_-_51538118 0.55 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr19_+_51754526 0.54 ENST00000596117.1
SIGLECL1
SIGLEC family like 1
chr22_-_39928823 0.53 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr17_-_72619783 0.52 ENST00000328630.3
CD300E
CD300e molecule
chr2_-_165698662 0.52 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr20_-_1472029 0.51 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr7_-_150721570 0.51 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr14_+_22958441 0.51 ENST00000390488.1
TRAJ49
T cell receptor alpha joining 49
chr11_+_125616184 0.50 ENST00000305738.5
ENST00000437148.2
PATE1
prostate and testis expressed 1
chr4_+_178230985 0.50 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr3_+_118866222 0.50 ENST00000490594.1
RP11-484M3.5
Uncharacterized protein
chr2_+_114647617 0.50 ENST00000536059.1
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr19_-_47291843 0.49 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr5_-_39425222 0.48 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_+_55459808 0.48 ENST00000404735.1
RPS27A
ribosomal protein S27a
chr5_-_174871136 0.48 ENST00000393752.2
DRD1
dopamine receptor D1
chr4_+_103790462 0.47 ENST00000503643.1
CISD2
CDGSH iron sulfur domain 2
chr9_-_130679257 0.46 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr2_+_66666432 0.46 ENST00000495021.2
MEIS1
Meis homeobox 1
chr11_+_71249071 0.46 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr2_-_24149977 0.45 ENST00000238789.5
ATAD2B
ATPase family, AAA domain containing 2B
chr7_-_112726393 0.45 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr19_+_32516768 0.45 ENST00000593056.1
ENST00000588694.1
ENST00000585739.1
CTC-360P9.3
CTC-360P9.3
chr6_-_35888905 0.44 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr1_-_119869846 0.44 ENST00000457719.1
RP11-418J17.3
RP11-418J17.3
chr19_+_31658405 0.43 ENST00000589511.1
CTC-439O9.3
CTC-439O9.3
chr16_+_55512742 0.43 ENST00000568715.1
ENST00000219070.4
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_+_150264365 0.42 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr2_+_55459495 0.42 ENST00000272317.6
ENST00000449323.1
RPS27A
ribosomal protein S27a
chr22_+_27017921 0.42 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr1_+_171217622 0.40 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr20_-_1472121 0.40 ENST00000444444.2
SIRPB2
signal-regulatory protein beta 2
chr8_+_86851932 0.39 ENST00000517368.1
CTA-392E5.1
CTA-392E5.1
chr11_+_71259466 0.39 ENST00000528743.2
KRTAP5-9
keratin associated protein 5-9
chr14_+_23009190 0.39 ENST00000390532.1
TRAJ5
T cell receptor alpha joining 5
chr14_-_23446900 0.38 ENST00000556731.1
AJUBA
ajuba LIM protein
chr6_-_46703092 0.38 ENST00000541026.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr7_+_99971129 0.38 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chrX_-_65259914 0.37 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_65259900 0.37 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr19_-_55677920 0.37 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.9 2.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.9 2.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.9 3.4 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.7 2.1 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.6 2.4 GO:0009822 alkaloid catabolic process(GO:0009822)
0.4 3.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 1.7 GO:0070980 biphenyl catabolic process(GO:0070980)
0.3 4.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 0.8 GO:0019516 lactate oxidation(GO:0019516)
0.3 1.8 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.3 1.0 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 1.0 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.0 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.2 0.9 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 0.2 GO:0010157 response to chlorate(GO:0010157)
0.2 0.6 GO:0061485 memory T cell proliferation(GO:0061485)
0.2 0.8 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.6 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 1.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 1.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 1.7 GO:0071494 cellular response to UV-C(GO:0071494)
0.2 1.1 GO:0051552 flavone metabolic process(GO:0051552)
0.2 0.9 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 1.3 GO:0015811 L-cystine transport(GO:0015811)
0.2 0.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2 1.4 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.0 GO:0048241 epinephrine transport(GO:0048241)
0.1 5.6 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 10.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.7 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 1.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 22.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.7 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.5 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 1.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 1.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.1 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 8.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.9 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.3 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.4 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.7 GO:0072718 response to cisplatin(GO:0072718)
0.0 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.0 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 3.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.0 5.3 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0043449 coumarin metabolic process(GO:0009804) cellular alkene metabolic process(GO:0043449)
0.0 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0010446 response to alkaline pH(GO:0010446)
0.0 2.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 1.2 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.8 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 1.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 2.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.1 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 2.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.2 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.6 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.7 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.7 2.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 4.3 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 1.1 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 10.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.9 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.0 GO:0042825 TAP complex(GO:0042825)
0.1 0.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.7 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 3.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 3.2 GO:0070069 cytochrome complex(GO:0070069)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 4.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.9 GO:0005694 chromosome(GO:0005694)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0016939 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.0 2.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 2.6 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 4.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005884 actin filament(GO:0005884)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 21.8 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.7 4.4 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.6 2.4 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.5 2.7 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.3 1.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 2.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.3 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.0 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 2.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 0.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.2 0.6 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 0.9 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.2 0.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 10.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 0.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.0 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.7 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 1.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.5 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 3.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 3.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 23.7 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.0 GO:0019863 IgE binding(GO:0019863)
0.1 1.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 2.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 3.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 10.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 4.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 3.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 3.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors