ISMARA results: TEAD3

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Illumina Body Map 2, young vs old

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Results for TEAD3_TEAD1

Z-value: 0.03

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol	Gene ID	Gene Info
TEAD3 Ensembl NCBI GeneCards UniProt	ENSG00000007866.14	TEA domain transcription factor 3
TEAD1 Ensembl NCBI GeneCards UniProt	ENSG00000187079.10	TEA domain transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TEAD1	hg19_v2_chr11_+_12766583_12766592	0.90	2.1e-12	Click!
TEAD3	hg19_v2_chr6_-_35464817_35464894	0.79	8.3e-08	Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_-_132272504 Show fit	33.59	ENST00000367976.3	CTGF Ensembl NCBI GeneCards UniProt Show fit	connective tissue growth factor
chr1_-_16344500 Show fit	27.53	ENST00000406363.2 ENST00000411503.1 ENST00000545268.1 ENST00000487046.1	HSPB7 Ensembl NCBI GeneCards UniProt Show fit	heat shock 27kDa protein family, member 7 (cardiovascular)
chr3_-_119379427 Show fit	26.48	ENST00000264231.3 ENST00000468801.1 ENST00000538678.1	POPDC2 Ensembl NCBI GeneCards UniProt Show fit	popeye domain containing 2
chr7_+_128470431 Show fit	25.86	ENST00000325888.8 ENST00000346177.6	FLNC Ensembl NCBI GeneCards UniProt Show fit	filamin C, gamma
chr3_-_119379719 Show fit	23.38	ENST00000493094.1	POPDC2 Ensembl NCBI GeneCards UniProt Show fit	popeye domain containing 2
chr14_-_23904861 Show fit	23.19	ENST00000355349.3	MYH7 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 7, cardiac muscle, beta
chr5_-_138842286 Show fit	20.40	ENST00000515823.1	ECSCR Ensembl NCBI GeneCards UniProt Show fit	endothelial cell surface expressed chemotaxis and apoptosis regulator
chr11_-_111781454 Show fit	18.02	ENST00000533280.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr4_-_186733363 Show fit	18.01	ENST00000393523.2 ENST00000393528.3 ENST00000449407.2	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr1_+_86046433 Show fit	17.38	ENST00000451137.2	CYR61 Ensembl NCBI GeneCards UniProt Show fit	cysteine-rich, angiogenic inducer, 61
chr10_-_90712520 Show fit	16.84	ENST00000224784.6	ACTA2 Ensembl NCBI GeneCards UniProt Show fit	actin, alpha 2, smooth muscle, aorta
chr14_-_23877474 Show fit	16.54	ENST00000405093.3	MYH6 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 6, cardiac muscle, alpha
chr17_-_40575535 Show fit	16.37	ENST00000357037.5	PTRF Ensembl NCBI GeneCards UniProt Show fit	polymerase I and transcript release factor
chr11_+_66824276 Show fit	14.88	ENST00000308831.2	RHOD Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member D
chr11_+_66824346 Show fit	14.87	ENST00000532559.1	RHOD Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member D
chr10_+_123872483 Show fit	14.75	ENST00000369001.1	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming, acidic coiled-coil containing protein 2
chr10_+_24498060 Show fit	14.75	ENST00000376454.3 ENST00000376452.3	KIAA1217 Ensembl NCBI GeneCards UniProt Show fit	KIAA1217
chr15_+_96869165 Show fit	14.26	ENST00000421109.2	NR2F2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2, group F, member 2
chr16_-_122619 Show fit	14.08	ENST00000262316.6	RHBDF1 Ensembl NCBI GeneCards UniProt Show fit	rhomboid 5 homolog 1 (Drosophila)
chr10_+_24497704 Show fit	13.96	ENST00000376456.4 ENST00000458595.1	KIAA1217 Ensembl NCBI GeneCards UniProt Show fit	KIAA1217
chr12_-_7245125 Show fit	13.81	ENST00000542285.1 ENST00000540610.1	C1R Ensembl NCBI GeneCards UniProt Show fit	complement component 1, r subcomponent
chr3_-_112360116 Show fit	13.51	ENST00000206423.3 ENST00000439685.2	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr11_+_66824303 Show fit	13.49	ENST00000533360.1	RHOD Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member D
chr1_-_201438282 Show fit	13.26	ENST00000367311.3 ENST00000367309.1	PHLDA3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology-like domain, family A, member 3
chr4_-_187644930 Show fit	13.06	ENST00000441802.2	FAT1 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 1
chr4_+_184020398 Show fit	12.99	ENST00000403733.3 ENST00000378925.3	WWC2 Ensembl NCBI GeneCards UniProt Show fit	WW and C2 domain containing 2
chr6_-_35464817 Show fit	12.96	ENST00000338863.7	TEAD3 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 3
chr6_-_35464727 Show fit	12.83	ENST00000402886.3	TEAD3 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 3
chr1_-_26394114 Show fit	12.69	ENST00000374272.3	TRIM63 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 63, E3 ubiquitin protein ligase
chr12_-_7245152 Show fit	12.50	ENST00000542220.2	C1R Ensembl NCBI GeneCards UniProt Show fit	complement component 1, r subcomponent
chr6_+_118869452 Show fit	12.45	ENST00000357525.5	PLN Ensembl NCBI GeneCards UniProt Show fit	phospholamban
chr9_+_72658490 Show fit	12.34	ENST00000377182.4	MAMDC2 Ensembl NCBI GeneCards UniProt Show fit	MAM domain containing 2
chr6_+_30850697 Show fit	12.03	ENST00000509639.1 ENST00000412274.2 ENST00000507901.1 ENST00000507046.1 ENST00000437124.2 ENST00000454612.2 ENST00000396342.2	DDR1 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 1
chr4_-_186732892 Show fit	11.91	ENST00000451958.1 ENST00000439914.1 ENST00000428330.1 ENST00000429056.1	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr12_-_7245018 Show fit	11.88	ENST00000543835.1 ENST00000535233.2	C1R Ensembl NCBI GeneCards UniProt Show fit	complement component 1, r subcomponent
chr17_-_27949911 Show fit	11.62	ENST00000492276.2 ENST00000345068.5 ENST00000584602.1	CORO6 Ensembl NCBI GeneCards UniProt Show fit	coronin 6
chr19_+_45409011 Show fit	11.58	ENST00000252486.4 ENST00000446996.1 ENST00000434152.1	APOE Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein E
chr12_-_96184533 Show fit	11.56	ENST00000343702.4 ENST00000344911.4	NTN4 Ensembl NCBI GeneCards UniProt Show fit	netrin 4
chr11_-_111782484 Show fit	11.50	ENST00000533971.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr15_+_63334831 Show fit	11.33	ENST00000288398.6 ENST00000358278.3 ENST00000560445.1 ENST00000403994.3 ENST00000357980.4 ENST00000559556.1 ENST00000559397.1 ENST00000267996.7 ENST00000560970.1	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1 (alpha)
chr12_-_96184913 Show fit	11.31	ENST00000538383.1	NTN4 Ensembl NCBI GeneCards UniProt Show fit	netrin 4
chr2_-_217560248 Show fit	11.29	ENST00000233813.4	IGFBP5 Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor binding protein 5
chr4_-_152149033 Show fit	11.23	ENST00000514152.1	SH3D19 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing 19
chr11_-_111782696 Show fit	10.92	ENST00000227251.3 ENST00000526180.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr14_-_89021077 Show fit	10.82	ENST00000556564.1	PTPN21 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 21
chr8_-_82395461 Show fit	10.57	ENST00000256104.4	FABP4 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 4, adipocyte
chr5_-_38595498 Show fit	10.50	ENST00000263409.4	LIFR Ensembl NCBI GeneCards UniProt Show fit	leukemia inhibitory factor receptor alpha
chr12_-_7245080 Show fit	10.48	ENST00000541042.1 ENST00000540242.1	C1R Ensembl NCBI GeneCards UniProt Show fit	complement component 1, r subcomponent
chr15_+_62853562 Show fit	10.48	ENST00000561311.1	TLN2 Ensembl NCBI GeneCards UniProt Show fit	talin 2
chr1_-_1293904 Show fit	10.24	ENST00000309212.6 ENST00000342753.4 ENST00000445648.2	MXRA8 Ensembl NCBI GeneCards UniProt Show fit	matrix-remodelling associated 8
chr11_-_111781554 Show fit	10.06	ENST00000526167.1 ENST00000528961.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr2_+_27505260 Show fit	9.99	ENST00000380075.2 ENST00000296098.4	TRIM54 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 54
chr1_+_78354330 Show fit	9.99	ENST00000440324.1	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin (F actin binding protein)
chr16_+_30387141 Show fit	9.95	ENST00000566955.1	MYLPF Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr11_-_111781610 Show fit	9.94	ENST00000525823.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin, alpha B
chr3_-_134093275 Show fit	9.93	ENST00000513145.1 ENST00000422605.2	AMOTL2 Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 2
chr7_+_116165754 Show fit	9.69	ENST00000405348.1	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1, caveolae protein, 22kDa
chr1_-_201346761 Show fit	9.67	ENST00000455702.1 ENST00000422165.1 ENST00000367318.5 ENST00000367320.2 ENST00000438742.1 ENST00000412633.1 ENST00000458432.2 ENST00000421663.2 ENST00000367322.1 ENST00000509001.1	TNNT2 Ensembl NCBI GeneCards UniProt Show fit	troponin T type 2 (cardiac)
chr1_+_78354175 Show fit	9.55	ENST00000401035.3 ENST00000457030.1 ENST00000330010.8	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin (F actin binding protein)
chr7_+_116165038 Show fit	9.53	ENST00000393470.1	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1, caveolae protein, 22kDa
chr19_+_15218180 Show fit	9.50	ENST00000342784.2 ENST00000597977.1 ENST00000600440.1	SYDE1 Ensembl NCBI GeneCards UniProt Show fit	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr10_-_17659234 Show fit	9.44	ENST00000466335.1	PTPLA Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_-_134093395 Show fit	9.35	ENST00000249883.5	AMOTL2 Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 2
chr1_+_78354243 Show fit	9.34	ENST00000294624.8	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin (F actin binding protein)
chr19_+_34972543 Show fit	9.13	ENST00000590071.2	WTIP Ensembl NCBI GeneCards UniProt Show fit	Wilms tumor 1 interacting protein
chr1_-_229569834 Show fit	9.02	ENST00000366684.3 ENST00000366683.2	ACTA1 Ensembl NCBI GeneCards UniProt Show fit	actin, alpha 1, skeletal muscle
chr1_-_94050668 Show fit	9.01	ENST00000539242.1	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	breast cancer anti-estrogen resistance 3
chr1_-_201915590 Show fit	8.93	ENST00000367288.4	LMOD1 Ensembl NCBI GeneCards UniProt Show fit	leiomodin 1 (smooth muscle)
chr2_+_228029281 Show fit	8.89	ENST00000396578.3	COL4A3 Ensembl NCBI GeneCards UniProt Show fit	collagen, type IV, alpha 3 (Goodpasture antigen)
chr17_-_39677971 Show fit	8.88	ENST00000393976.2	KRT15 Ensembl NCBI GeneCards UniProt Show fit	keratin 15
chr8_+_70378852 Show fit	8.87	ENST00000525061.1 ENST00000458141.2 ENST00000260128.4	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chrX_-_46187069 Show fit	8.70	ENST00000446884.1	RP1-30G7.2 Ensembl NCBI GeneCards UniProt Show fit	RP1-30G7.2
chr1_-_11918988 Show fit	8.69	ENST00000376468.3	NPPB Ensembl NCBI GeneCards UniProt Show fit	natriuretic peptide B
chr7_+_134464376 Show fit	8.60	ENST00000454108.1 ENST00000361675.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr4_-_186733119 Show fit	8.49	ENST00000419063.1	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr7_+_134464414 Show fit	8.45	ENST00000361901.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr1_+_78354297 Show fit	8.42	ENST00000334785.7	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin (F actin binding protein)
chr22_+_26138108 Show fit	8.39	ENST00000536101.1 ENST00000335473.7 ENST00000407587.2	MYO18B Ensembl NCBI GeneCards UniProt Show fit	myosin XVIIIB
chr4_+_41614720 Show fit	8.25	ENST00000509277.1	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr11_+_114166536 Show fit	8.25	ENST00000299964.3	NNMT Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr1_+_183155373 Show fit	8.21	ENST00000493293.1 ENST00000264144.4	LAMC2 Ensembl NCBI GeneCards UniProt Show fit	laminin, gamma 2
chr9_-_13175823 Show fit	8.17	ENST00000545857.1	MPDZ Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain protein
chr16_+_28889703 Show fit	8.11	ENST00000357084.3	ATP2A1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_+_50691437 Show fit	8.07	ENST00000598205.1	MYH14 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 14, non-muscle
chr1_-_95391315 Show fit	8.05	ENST00000545882.1 ENST00000415017.1	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3, acidic
chr4_+_41614909 Show fit	8.01	ENST00000509454.1 ENST00000396595.3 ENST00000381753.4	LIMCH1 Ensembl NCBI GeneCards UniProt Show fit	LIM and calponin homology domains 1
chr1_-_24438664 Show fit	7.94	ENST00000374434.3 ENST00000330966.7 ENST00000329601.7	MYOM3 Ensembl NCBI GeneCards UniProt Show fit	myomesin 3
chr16_+_28889801 Show fit	7.89	ENST00000395503.4	ATP2A1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr18_+_32173276 Show fit	7.86	ENST00000591816.1 ENST00000588125.1 ENST00000598334.1 ENST00000588684.1 ENST00000554864.3 ENST00000399121.5 ENST00000595022.1 ENST00000269190.7 ENST00000399097.3	DTNA Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin, alpha
chr11_+_111782934 Show fit	7.80	ENST00000304298.3	HSPB2 Ensembl NCBI GeneCards UniProt Show fit	Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr6_-_75915757 Show fit	7.73	ENST00000322507.8	COL12A1 Ensembl NCBI GeneCards UniProt Show fit	collagen, type XII, alpha 1
chr16_+_30386098 Show fit	7.71	ENST00000322861.7	MYLPF Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr12_-_47219733 Show fit	7.66	ENST00000547477.1 ENST00000447411.1 ENST00000266579.4	SLC38A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 4
chr5_+_145316120 Show fit	7.65	ENST00000359120.4	SH3RF2 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing ring finger 2
chr14_-_23451845 Show fit	7.65	ENST00000262713.2	AJUBA Ensembl NCBI GeneCards UniProt Show fit	ajuba LIM protein
chr15_-_99548775 Show fit	7.56	ENST00000378919.6	PGPEP1L Ensembl NCBI GeneCards UniProt Show fit	pyroglutamyl-peptidase I-like
chr11_-_8832521 Show fit	7.55	ENST00000530438.1	ST5 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 5
chr16_-_46797149 Show fit	7.50	ENST00000536476.1	MYLK3 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase 3
chr3_+_9944303 Show fit	7.44	ENST00000421412.1 ENST00000295980.3	IL17RE Ensembl NCBI GeneCards UniProt Show fit	interleukin 17 receptor E
chr3_-_134093738 Show fit	7.44	ENST00000506107.1	AMOTL2 Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 2
chr12_-_8815404 Show fit	7.42	ENST00000359478.2 ENST00000396549.2	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr1_-_59043166 Show fit	7.35	ENST00000371225.2	TACSTD2 Ensembl NCBI GeneCards UniProt Show fit	tumor-associated calcium signal transducer 2
chr10_+_69869237 Show fit	7.29	ENST00000373675.3	MYPN Ensembl NCBI GeneCards UniProt Show fit	myopalladin
chr12_+_27677085 Show fit	7.28	ENST00000545334.1 ENST00000540114.1 ENST00000537927.1 ENST00000318304.8 ENST00000535047.1 ENST00000542629.1 ENST00000228425.6	PPFIBP1 Ensembl NCBI GeneCards UniProt Show fit	PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr12_-_8815215 Show fit	7.28	ENST00000544889.1 ENST00000543369.1	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr4_-_186877502 Show fit	7.15	ENST00000431902.1 ENST00000284776.7 ENST00000415274.1	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr12_-_111358372 Show fit	7.15	ENST00000548438.1 ENST00000228841.8	MYL2 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 2, regulatory, cardiac, slow
chr6_+_53883790 Show fit	6.97	ENST00000509997.1	MLIP Ensembl NCBI GeneCards UniProt Show fit	muscular LMNA-interacting protein
chr22_+_41956767 Show fit	6.97	ENST00000306149.7	CSDC2 Ensembl NCBI GeneCards UniProt Show fit	cold shock domain containing C2, RNA binding
chr11_-_47470703 Show fit	6.91	ENST00000298854.2	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chrX_+_99899180 Show fit	6.89	ENST00000373004.3	SRPX2 Ensembl NCBI GeneCards UniProt Show fit	sushi-repeat containing protein, X-linked 2
chr4_+_55096489 Show fit	6.86	ENST00000504461.1	PDGFRA Ensembl NCBI GeneCards UniProt Show fit	platelet-derived growth factor receptor, alpha polypeptide
chr19_-_54984354 Show fit	6.85	ENST00000301200.2	CDC42EP5 Ensembl NCBI GeneCards UniProt Show fit	CDC42 effector protein (Rho GTPase binding) 5
chr10_+_112404132 Show fit	6.76	ENST00000369519.3	RBM20 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 20
chr14_+_32964258 Show fit	6.62	ENST00000556638.1	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A kinase (PRKA) anchor protein 6
chr12_+_3068466 Show fit	6.61	ENST00000358409.2	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 4
chr14_+_63671105 Show fit	6.57	ENST00000316754.3	RHOJ Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr11_-_76381029 Show fit	6.57	ENST00000407242.2 ENST00000421973.1	LRRC32 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 32
chr2_-_211179883 Show fit	6.43	ENST00000352451.3	MYL1 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 1, alkali; skeletal, fast
chr12_+_3068544 Show fit	6.42	ENST00000540314.1 ENST00000536826.1 ENST00000359864.2	TEAD4 Ensembl NCBI GeneCards UniProt Show fit	TEA domain family member 4
chr7_+_134430212 Show fit	6.30	ENST00000436461.2	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr11_+_46299199 Show fit	6.20	ENST00000529193.1 ENST00000288400.3	CREB3L1 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 3-like 1
chr2_-_218770168 Show fit	6.19	ENST00000413554.1	TNS1 Ensembl NCBI GeneCards UniProt Show fit	tensin 1
chr20_-_62680984 Show fit	6.15	ENST00000340356.7	SOX18 Ensembl NCBI GeneCards UniProt Show fit	SRY (sex determining region Y)-box 18
chr11_-_119249805 Show fit	6.15	ENST00000527843.1	USP2 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 2
chr4_-_186732048 Show fit	6.14	ENST00000448662.2 ENST00000439049.1 ENST00000420158.1 ENST00000431808.1 ENST00000319471.9	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr17_+_70117153 Show fit	6.10	ENST00000245479.2	SOX9 Ensembl NCBI GeneCards UniProt Show fit	SRY (sex determining region Y)-box 9
chr11_-_47470682 Show fit	6.04	ENST00000529341.1 ENST00000352508.3	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chr17_+_4901199 Show fit	6.03	ENST00000320785.5 ENST00000574165.1	KIF1C Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 1C
chr19_-_49567124 Show fit	6.02	ENST00000301411.3	NTF4 Ensembl NCBI GeneCards UniProt Show fit	neurotrophin 4
chr10_+_50507232 Show fit	5.99	ENST00000374144.3	C10orf71 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 71
chr19_-_46272462 Show fit	5.98	ENST00000317578.6	SIX5 Ensembl NCBI GeneCards UniProt Show fit	SIX homeobox 5
chr12_-_8815299 Show fit	5.97	ENST00000535336.1	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr16_+_23194033 Show fit	5.95	ENST00000300061.2	SCNN1G Ensembl NCBI GeneCards UniProt Show fit	sodium channel, non-voltage-gated 1, gamma subunit
chr10_-_97175444 Show fit	5.95	ENST00000486141.2	SORBS1 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 1
chr6_+_53883708 Show fit	5.93	ENST00000514921.1 ENST00000274897.5 ENST00000370877.2	MLIP Ensembl NCBI GeneCards UniProt Show fit	muscular LMNA-interacting protein
chr16_-_46782221 Show fit	5.85	ENST00000394809.4	MYLK3 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase 3
chr4_+_169552748 Show fit	5.85	ENST00000504519.1 ENST00000512127.1	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr1_+_114522049 Show fit	5.83	ENST00000369551.1 ENST00000320334.4	OLFML3 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin-like 3
chr12_-_12419905 Show fit	5.83	ENST00000535731.1	LRP6 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor-related protein 6
chr4_+_166300084 Show fit	5.82	ENST00000402744.4	CPE Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase E
chr2_-_216257849 Show fit	5.77	ENST00000456923.1	FN1 Ensembl NCBI GeneCards UniProt Show fit	fibronectin 1
chr4_+_110834033 Show fit	5.77	ENST00000509793.1 ENST00000265171.5	EGF Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor
chr3_-_149375783 Show fit	5.75	ENST00000467467.1 ENST00000460517.1 ENST00000360632.3	WWTR1 Ensembl NCBI GeneCards UniProt Show fit	WW domain containing transcription regulator 1
chr10_+_123923205 Show fit	5.70	ENST00000369004.3 ENST00000260733.3	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming, acidic coiled-coil containing protein 2
chrX_-_10851762 Show fit	5.69	ENST00000380785.1 ENST00000380787.1	MID1 Ensembl NCBI GeneCards UniProt Show fit	midline 1 (Opitz/BBB syndrome)
chr22_+_24577183 Show fit	5.67	ENST00000358321.3	SUSD2 Ensembl NCBI GeneCards UniProt Show fit	sushi domain containing 2
chr21_-_40033618 Show fit	5.63	ENST00000417133.2 ENST00000398910.1 ENST00000442448.1	ERG Ensembl NCBI GeneCards UniProt Show fit	v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_+_42423872 Show fit	5.57	ENST00000230882.4 ENST00000357703.3	GHR Ensembl NCBI GeneCards UniProt Show fit	growth hormone receptor
chr21_+_17566643 Show fit	5.54	ENST00000419952.1 ENST00000445461.2	LINC00478 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 478
chr6_+_19837592 Show fit	5.53	ENST00000378700.3	ID4 Ensembl NCBI GeneCards UniProt Show fit	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_+_170366203 Show fit	5.52	ENST00000284669.1	KLHL41 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 41
chr2_+_189157536 Show fit	5.50	ENST00000409580.1 ENST00000409637.3	GULP1 Ensembl NCBI GeneCards UniProt Show fit	GULP, engulfment adaptor PTB domain containing 1
chr13_-_33760216 Show fit	5.46	ENST00000255486.4	STARD13 Ensembl NCBI GeneCards UniProt Show fit	StAR-related lipid transfer (START) domain containing 13
chr10_+_81891416 Show fit	5.45	ENST00000372270.2	PLAC9 Ensembl NCBI GeneCards UniProt Show fit	placenta-specific 9
chr9_+_27109440 Show fit	5.45	ENST00000519080.1	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK tyrosine kinase, endothelial
chr17_-_73511504 Show fit	5.43	ENST00000581870.1	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr11_-_8832182 Show fit	5.41	ENST00000527510.1 ENST00000528527.1 ENST00000528523.1 ENST00000313726.6	ST5 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 5
chr11_-_68780824 Show fit	5.41	ENST00000441623.1 ENST00000309099.6	MRGPRF Ensembl NCBI GeneCards UniProt Show fit	MAS-related GPR, member F
chr10_+_50507181 Show fit	5.40	ENST00000323868.4	C10orf71 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 71
chr1_-_161279749 Show fit	5.37	ENST00000533357.1 ENST00000360451.6 ENST00000336559.4	MPZ Ensembl NCBI GeneCards UniProt Show fit	myelin protein zero
chr3_-_52868931 Show fit	5.31	ENST00000486659.1	MUSTN1 Ensembl NCBI GeneCards UniProt Show fit	musculoskeletal, embryonic nuclear protein 1
chr9_-_14308004 Show fit	5.31	ENST00000493697.1	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I/B
chr9_+_109694914 Show fit	5.30	ENST00000542028.1	ZNF462 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 462
chr4_-_186877806 Show fit	5.30	ENST00000355634.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr17_-_73511584 Show fit	5.29	ENST00000321617.3	CASKIN2 Ensembl NCBI GeneCards UniProt Show fit	CASK interacting protein 2
chr2_+_189157498 Show fit	5.28	ENST00000359135.3	GULP1 Ensembl NCBI GeneCards UniProt Show fit	GULP, engulfment adaptor PTB domain containing 1
chr9_+_27109392 Show fit	5.28	ENST00000406359.4	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK tyrosine kinase, endothelial
chr1_+_178310581 Show fit	5.22	ENST00000462775.1	RASAL2 Ensembl NCBI GeneCards UniProt Show fit	RAS protein activator like 2
chr1_+_66999799 Show fit	5.20	ENST00000371035.3 ENST00000371036.3 ENST00000371037.4	SGIP1 Ensembl NCBI GeneCards UniProt Show fit	SH3-domain GRB2-like (endophilin) interacting protein 1
chr5_-_58882219 Show fit	5.19	ENST00000505453.1 ENST00000360047.5	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D, cAMP-specific
chr14_+_63671577 Show fit	5.18	ENST00000555125.1	RHOJ Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr3_+_9944492 Show fit	5.18	ENST00000383814.3 ENST00000454190.2 ENST00000454992.1	IL17RE Ensembl NCBI GeneCards UniProt Show fit	interleukin 17 receptor E
chr15_-_48937982 Show fit	5.11	ENST00000316623.5	FBN1 Ensembl NCBI GeneCards UniProt Show fit	fibrillin 1
chr17_+_73717516 Show fit	5.06	ENST00000200181.3 ENST00000339591.3	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 4
chr11_-_47470591 Show fit	5.01	ENST00000524487.1	RAPSN Ensembl NCBI GeneCards UniProt Show fit	receptor-associated protein of the synapse
chr3_-_66024213 Show fit	4.97	ENST00000483466.1	MAGI1 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 1
chrX_-_33229636 Show fit	4.96	ENST00000357033.4	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr12_-_8815477 Show fit	4.92	ENST00000433590.2	MFAP5 Ensembl NCBI GeneCards UniProt Show fit	microfibrillar associated protein 5
chr11_+_101981169 Show fit	4.92	ENST00000526343.1 ENST00000282441.5 ENST00000537274.1 ENST00000345877.2	YAP1 Ensembl NCBI GeneCards UniProt Show fit	Yes-associated protein 1
chr15_+_65369082 Show fit	4.92	ENST00000432196.2	KBTBD13 Ensembl NCBI GeneCards UniProt Show fit	kelch repeat and BTB (POZ) domain containing 13
chr16_+_30907927 Show fit	4.90	ENST00000279804.2 ENST00000395019.3	CTF1 Ensembl NCBI GeneCards UniProt Show fit	cardiotrophin 1
chr6_-_55740352 Show fit	4.83	ENST00000370830.3	BMP5 Ensembl NCBI GeneCards UniProt Show fit	bone morphogenetic protein 5
chr14_-_23446900 Show fit	4.81	ENST00000556731.1	AJUBA Ensembl NCBI GeneCards UniProt Show fit	ajuba LIM protein
chr1_+_62417957 Show fit	4.72	ENST00000307297.7 ENST00000543708.1	INADL Ensembl NCBI GeneCards UniProt Show fit	InaD-like (Drosophila)
chr9_+_113431029 Show fit	4.72	ENST00000189978.5 ENST00000374448.4 ENST00000374440.3	MUSK Ensembl NCBI GeneCards UniProt Show fit	muscle, skeletal, receptor tyrosine kinase
chr11_+_7506713 Show fit	4.71	ENST00000329293.3 ENST00000534244.1	OLFML1 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin-like 1
chr9_+_102584128 Show fit	4.69	ENST00000338488.4 ENST00000395097.2	NR4A3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4, group A, member 3
chr3_-_149051444 Show fit	4.68	ENST00000296059.2	TM4SF18 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 18
chr1_+_19967014 Show fit	4.67	ENST00000428975.1	NBL1 Ensembl NCBI GeneCards UniProt Show fit	neuroblastoma 1, DAN family BMP antagonist
chr4_+_111397216 Show fit	4.66	ENST00000265162.5	ENPEP Ensembl NCBI GeneCards UniProt Show fit	glutamyl aminopeptidase (aminopeptidase A)
chr5_-_149516966 Show fit	4.66	ENST00000517957.1	PDGFRB Ensembl NCBI GeneCards UniProt Show fit	platelet-derived growth factor receptor, beta polypeptide
chr5_+_150406527 Show fit	4.62	ENST00000520059.1	GPX3 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 3 (plasma)
chr19_-_49371711 Show fit	4.62	ENST00000355496.5 ENST00000263265.6	PLEKHA4 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr17_+_73717407 Show fit	4.62	ENST00000579662.1	ITGB4 Ensembl NCBI GeneCards UniProt Show fit	integrin, beta 4
chr5_-_41213607 Show fit	4.61	ENST00000337836.5 ENST00000433294.1	C6 Ensembl NCBI GeneCards UniProt Show fit	complement component 6
chr8_-_81787006 Show fit	4.56	ENST00000327835.3	ZNF704 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 704
chr15_+_74466744 Show fit	4.56	ENST00000560862.1 ENST00000395118.1	ISLR Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily containing leucine-rich repeat
chr3_-_149051194 Show fit	4.55	ENST00000470080.1	TM4SF18 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 4 L six family member 18
chr4_+_55096010 Show fit	4.55	ENST00000503856.1	PDGFRA Ensembl NCBI GeneCards UniProt Show fit	platelet-derived growth factor receptor, alpha polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.2	33.6	GO:0034059	response to anoxia(GO:0034059)
9.8	39.2	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
6.4	19.2	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
6.0	18.0	GO:1900073	regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
4.3	25.9	GO:0090131	mesenchyme migration(GO:0090131)
4.1	12.4	GO:1901876	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
3.9	11.6	GO:2000646	lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
3.8	22.9	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
3.8	11.3	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
3.6	14.3	GO:0009956	radial pattern formation(GO:0009956)
3.3	13.3	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
3.2	9.7	GO:0035261	external genitalia morphogenesis(GO:0035261) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
3.1	6.1	GO:0072197	ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
2.7	13.4	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
2.5	17.8	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
2.5	12.7	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.5	35.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
2.5	19.9	GO:0072276	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.4	60.4	GO:0007021	tubulin complex assembly(GO:0007021)
2.4	12.1	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
2.4	9.5	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
2.4	61.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
2.2	17.4	GO:0003278	apoptotic process involved in heart morphogenesis(GO:0003278)
2.1	4.2	GO:0007266	Rho protein signal transduction(GO:0007266)
2.1	16.8	GO:0048014	Tie signaling pathway(GO:0048014)
2.0	6.0	GO:0008052	sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
2.0	25.8	GO:0055059	asymmetric neuroblast division(GO:0055059)
2.0	5.9	GO:0071676	negative regulation of mononuclear cell migration(GO:0071676)
1.9	9.7	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
1.9	5.8	GO:1904237	regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.9	9.3	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.8	14.5	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.8	12.3	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
1.7	10.3	GO:0061107	seminal vesicle development(GO:0061107)
1.6	13.1	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
1.6	1.6	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
1.6	6.5	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
1.6	3.3	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.6	4.7	GO:0032765	positive regulation of mast cell cytokine production(GO:0032765)
1.5	6.0	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.4	21.1	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
1.4	4.2	GO:0035378	carbon dioxide transmembrane transport(GO:0035378)
1.4	70.6	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.3	4.0	GO:2000830	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.3	4.0	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.3	3.9	GO:0048320	axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
1.2	6.2	GO:0048865	stem cell fate commitment(GO:0048865)
1.2	9.8	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
1.2	9.5	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
1.2	5.8	GO:0030070	insulin processing(GO:0030070)
1.1	12.6	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
1.1	6.5	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.1	14.0	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.0	1.0	GO:1990785	response to water-immersion restraint stress(GO:1990785)
1.0	25.0	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.0	13.0	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.0	9.9	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.0	56.1	GO:0035329	hippo signaling(GO:0035329)
1.0	6.9	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.0	6.8	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.9	6.6	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.9	4.6	GO:0001970	positive regulation of activation of membrane attack complex(GO:0001970)
0.9	5.5	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.9	8.1	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.9	4.5	GO:0042360	vitamin E metabolic process(GO:0042360)
0.8	2.5	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.8	14.2	GO:0035878	nail development(GO:0035878)
0.8	8.9	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.8	5.6	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.8	5.6	GO:0000255	allantoin metabolic process(GO:0000255)
0.8	8.7	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.8	6.2	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.8	1.5	GO:0009644	response to high light intensity(GO:0009644)
0.7	6.7	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.7	18.8	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.7	1.4	GO:0002035	brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.7	12.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.7	11.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.7	4.7	GO:0051012	microtubule sliding(GO:0051012)
0.7	4.6	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.6	3.1	GO:1903412	response to bile acid(GO:1903412)
0.6	0.6	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.6	6.8	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.6	3.6	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6	4.1	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.6	38.5	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.6	4.7	GO:0002005	angiotensin catabolic process in blood(GO:0002005)
0.6	2.3	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.6	9.9	GO:0035372	protein localization to microtubule(GO:0035372)
0.6	11.2	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6	2.8	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6	3.3	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5	1.6	GO:0097106	postsynaptic density organization(GO:0097106)
0.5	10.2	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.5	25.6	GO:0060216	definitive hemopoiesis(GO:0060216)
0.5	10.2	GO:0045475	locomotor rhythm(GO:0045475)
0.5	3.5	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.5	35.6	GO:0048747	muscle fiber development(GO:0048747)
0.5	5.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.5	11.8	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.5	7.9	GO:0071285	cellular response to lithium ion(GO:0071285)
0.5	1.8	GO:0046013	regulation of T cell homeostatic proliferation(GO:0046013)
0.5	6.4	GO:0015705	iodide transport(GO:0015705)
0.5	2.3	GO:0021778	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.4	1.8	GO:0042264	peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4	3.6	GO:1905150	regulation of voltage-gated sodium channel activity(GO:1905150)
0.4	1.3	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.4	2.6	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4	5.2	GO:0031272	regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.4	1.3	GO:0045360	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4	8.2	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4	8.6	GO:0070314	G1 to G0 transition(GO:0070314)
0.4	1.2	GO:0042245	RNA repair(GO:0042245)
0.4	9.3	GO:0035988	chondrocyte proliferation(GO:0035988)
0.4	1.2	GO:0006481	C-terminal protein methylation(GO:0006481)
0.4	2.0	GO:0060005	vestibular reflex(GO:0060005)
0.4	8.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.4	1.2	GO:1904888	cranial skeletal system development(GO:1904888)
0.4	52.0	GO:0002027	regulation of heart rate(GO:0002027)
0.4	2.3	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.4	11.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.4	3.3	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4	2.9	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.4	4.6	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	0.7	GO:0016999	antibiotic metabolic process(GO:0016999)
0.3	54.1	GO:0030449	regulation of complement activation(GO:0030449)
0.3	5.8	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.3	6.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.3	3.2	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	2.2	GO:0008218	bioluminescence(GO:0008218)
0.3	0.9	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.3	11.6	GO:0071625	vocalization behavior(GO:0071625)
0.3	2.2	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3	6.7	GO:0098743	cell aggregation(GO:0098743)
0.3	1.5	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.3	1.5	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3	4.1	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.3	7.9	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.3	1.7	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.3	0.3	GO:2000630	regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) positive regulation of miRNA metabolic process(GO:2000630)
0.3	1.4	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.3	3.6	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.3	3.0	GO:0006528	asparagine metabolic process(GO:0006528)
0.3	3.7	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	1.1	GO:0009224	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3	1.1	GO:0035690	cellular response to drug(GO:0035690)
0.3	8.7	GO:0006825	copper ion transport(GO:0006825)
0.2	1.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2	8.8	GO:0040023	establishment of nucleus localization(GO:0040023)
0.2	5.8	GO:0003334	keratinocyte development(GO:0003334)
0.2	3.2	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.2	1.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	1.4	GO:0003344	pericardium morphogenesis(GO:0003344)
0.2	3.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	0.2	GO:1903216	regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2	0.7	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.2	1.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
0.2	0.6	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.2	2.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.2	2.8	GO:0060056	mammary gland involution(GO:0060056)
0.2	2.3	GO:0051451	myoblast migration(GO:0051451)
0.2	3.7	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	4.2	GO:0035994	response to muscle stretch(GO:0035994)
0.2	1.0	GO:0052250	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2	0.6	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.2	5.2	GO:0097320	membrane tubulation(GO:0097320)
0.2	6.0	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.2	37.6	GO:0048706	embryonic skeletal system development(GO:0048706)
0.2	3.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	7.1	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.2	3.4	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	4.3	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.2	1.8	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.2	4.2	GO:0051764	actin crosslink formation(GO:0051764)
0.2	2.2	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.2	2.8	GO:0072189	ureter development(GO:0072189)
0.2	1.6	GO:0031120	snRNA pseudouridine synthesis(GO:0031120)
0.2	3.7	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.2	2.3	GO:1990118	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	2.4	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.2	1.8	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.2	1.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.2	2.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.2	0.8	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2	0.5	GO:0051758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.2	7.9	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.2	1.7	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2	2.6	GO:0061162	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	7.5	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	5.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	13.4	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.7	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.4	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.1	4.5	GO:0055078	sodium ion homeostasis(GO:0055078)
0.1	20.1	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.1	3.6	GO:0010842	retina layer formation(GO:0010842) retinal ganglion cell axon guidance(GO:0031290)
0.1	3.1	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.1	0.9	GO:0044245	polysaccharide digestion(GO:0044245)
0.1	0.7	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.1	1.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	6.8	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.1	0.9	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	18.9	GO:0021987	cerebral cortex development(GO:0021987)
0.1	5.3	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.1	0.3	GO:2000987	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1	1.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	19.8	GO:0008016	regulation of heart contraction(GO:0008016)
0.1	26.2	GO:0006936	muscle contraction(GO:0006936)
0.1	1.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	5.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.9	GO:0035585	calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1	0.3	GO:0071316	cellular response to nicotine(GO:0071316)
0.1	1.3	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1	0.5	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.1	0.5	GO:1900039	positive regulation of cellular response to hypoxia(GO:1900039)
0.1	1.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1	0.7	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.5	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1	0.6	GO:0019566	arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1	1.9	GO:0060325	face morphogenesis(GO:0060325)
0.1	3.0	GO:0030252	growth hormone secretion(GO:0030252)
0.1	4.0	GO:0007340	acrosome reaction(GO:0007340)
0.1	11.1	GO:0050709	negative regulation of protein secretion(GO:0050709)
0.1	0.5	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	1.8	GO:0006884	cell volume homeostasis(GO:0006884)
0.1	1.0	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	1.4	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	2.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.2	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.1	0.8	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	0.4	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	1.5	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	14.5	GO:0031032	actomyosin structure organization(GO:0031032)
0.1	1.4	GO:0006751	glutathione catabolic process(GO:0006751)
0.1	0.8	GO:0006828	manganese ion transport(GO:0006828)
0.1	0.8	GO:0044351	macropinocytosis(GO:0044351)
0.1	3.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.5	GO:0015811	L-cystine transport(GO:0015811)
0.1	0.5	GO:0051639	actin filament network formation(GO:0051639)
0.1	1.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.1	1.0	GO:0008286	insulin receptor signaling pathway(GO:0008286)
0.1	0.3	GO:0071934	thiamine transmembrane transport(GO:0071934)
0.1	0.6	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.1	1.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	1.4	GO:0051382	kinetochore assembly(GO:0051382)
0.1	3.2	GO:1901998	toxin transport(GO:1901998)
0.1	4.8	GO:0032465	regulation of cytokinesis(GO:0032465)
0.1	2.7	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.1	3.3	GO:0008542	visual learning(GO:0008542)
0.1	0.4	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1	0.3	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.0	6.0	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.2	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.2	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	4.2	GO:0051782	negative regulation of cell division(GO:0051782)
0.0	0.6	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	1.3	GO:0046710	GDP metabolic process(GO:0046710)
0.0	1.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	1.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.4	GO:0021681	cerebellar granular layer development(GO:0021681)
0.0	2.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	1.2	GO:0031638	zymogen activation(GO:0031638)
0.0	3.8	GO:0000271	polysaccharide biosynthetic process(GO:0000271)
0.0	1.3	GO:0007035	vacuolar acidification(GO:0007035)
0.0	2.1	GO:0051693	actin filament capping(GO:0051693)
0.0	3.1	GO:0007517	muscle organ development(GO:0007517)
0.0	1.6	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.6	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.4	GO:0000492	box C/D snoRNP assembly(GO:0000492)
0.0	1.7	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.5	GO:0030855	epithelial cell differentiation(GO:0030855)
0.0	0.8	GO:0008272	sulfate transport(GO:0008272)
0.0	2.6	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	1.8	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.3	GO:0043586	tongue development(GO:0043586)
0.0	1.8	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	1.2	GO:0007018	microtubule-based movement(GO:0007018)
0.0	0.6	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	9.1	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.5	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.6	GO:0017145	stem cell division(GO:0017145)
0.0	0.3	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.7	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	1.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.8	GO:0000187	activation of MAPK activity(GO:0000187)
0.0	8.8	GO:0006869	lipid transport(GO:0006869)
0.0	1.3	GO:0046785	microtubule polymerization(GO:0046785)
0.0	0.9	GO:0042438	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	1.4	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.5	GO:0007605	sensory perception of sound(GO:0007605)
0.0	0.5	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	1.1	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.0	1.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.8	GO:1903363	negative regulation of cellular protein catabolic process(GO:1903363)
0.0	2.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	1.0	GO:0043413	protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0	0.0	GO:0007343	egg activation(GO:0007343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.3	78.2	GO:0097512	cardiac myofibril(GO:0097512)
3.9	11.6	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
3.0	8.9	GO:0005900	oncostatin-M receptor complex(GO:0005900)
2.8	16.8	GO:0030485	smooth muscle contractile fiber(GO:0030485)
2.7	8.2	GO:0005863	striated muscle myosin thick filament(GO:0005863)
2.6	7.7	GO:0005595	collagen type XII trimer(GO:0005595)
2.1	8.2	GO:0005607	laminin-2 complex(GO:0005607)
2.0	52.0	GO:0032982	myosin filament(GO:0032982)
1.9	9.7	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.9	5.6	GO:0070195	growth hormone receptor complex(GO:0070195)
1.8	3.6	GO:1990584	cardiac Troponin complex(GO:1990584)
1.4	35.9	GO:0005859	muscle myosin complex(GO:0005859)
1.4	4.2	GO:0020005	symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.2	18.0	GO:0030478	actin cap(GO:0030478)
1.2	4.8	GO:0097182	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.1	28.4	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
1.1	13.0	GO:0016013	syntrophin complex(GO:0016013)
1.1	18.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.1	18.0	GO:0099634	postsynaptic specialization membrane(GO:0099634)
1.0	11.3	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
1.0	8.9	GO:0005587	collagen type IV trimer(GO:0005587)
1.0	4.9	GO:0071149	TEAD-2-YAP complex(GO:0071149)
1.0	14.5	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.9	6.0	GO:0005899	insulin receptor complex(GO:0005899)
0.8	2.5	GO:0005588	collagen type V trimer(GO:0005588)
0.8	3.0	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
0.7	42.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.7	22.9	GO:0005614	interstitial matrix(GO:0005614)
0.7	178.5	GO:0030018	Z disc(GO:0030018)
0.7	14.2	GO:0030056	hemidesmosome(GO:0030056)
0.7	13.1	GO:0032059	bleb(GO:0032059)
0.6	8.8	GO:0002116	semaphorin receptor complex(GO:0002116)
0.6	8.4	GO:0016461	unconventional myosin complex(GO:0016461)
0.5	22.4	GO:0009925	basal plasma membrane(GO:0009925)
0.5	1.5	GO:1990716	axonemal central apparatus(GO:1990716)
0.5	1.4	GO:0044299	C-fiber(GO:0044299)
0.5	4.6	GO:0005579	membrane attack complex(GO:0005579)
0.4	4.2	GO:0031674	I band(GO:0031674)
0.4	3.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4	17.9	GO:0005865	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.4	31.6	GO:0005801	cis-Golgi network(GO:0005801)
0.4	29.0	GO:0016235	aggresome(GO:0016235)
0.4	1.1	GO:0000806	Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124)
0.4	2.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.3	8.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	0.9	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3	3.9	GO:0016600	flotillin complex(GO:0016600)
0.3	6.0	GO:0034706	sodium channel complex(GO:0034706)
0.3	3.0	GO:0005610	laminin-5 complex(GO:0005610)
0.3	4.6	GO:0005869	dynactin complex(GO:0005869)
0.3	52.5	GO:0042383	sarcolemma(GO:0042383)
0.3	30.7	GO:0005604	basement membrane(GO:0005604)
0.3	6.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	7.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3	7.9	GO:0031672	A band(GO:0031672)
0.2	2.6	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	51.4	GO:0072562	blood microparticle(GO:0072562)
0.2	1.0	GO:0071942	XPC complex(GO:0071942)
0.2	1.2	GO:0043083	synaptic cleft(GO:0043083)
0.2	8.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.2	4.2	GO:0031941	filamentous actin(GO:0031941)
0.2	32.7	GO:0005923	bicellular tight junction(GO:0005923)
0.2	1.6	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1	2.1	GO:0044754	autolysosome(GO:0044754)
0.1	14.7	GO:0031526	brush border membrane(GO:0031526)
0.1	1.6	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	3.9	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.1	84.1	GO:0005667	transcription factor complex(GO:0005667)
0.1	14.4	GO:0005902	microvillus(GO:0005902)
0.1	10.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	0.6	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.1	2.3	GO:0034709	methylosome(GO:0034709)
0.1	0.6	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	12.5	GO:0005811	lipid particle(GO:0005811)
0.1	10.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	2.7	GO:0071004	U2-type prespliceosome(GO:0071004)
0.1	10.1	GO:0005938	cell cortex(GO:0005938)
0.1	5.9	GO:0005903	brush border(GO:0005903)
0.1	40.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	1.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	1.5	GO:0032039	integrator complex(GO:0032039)
0.1	10.5	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	1.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.6	GO:0071438	invadopodium membrane(GO:0071438)
0.1	7.2	GO:0005871	kinesin complex(GO:0005871)
0.1	37.8	GO:0005769	early endosome(GO:0005769)
0.1	0.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	0.9	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.5	GO:0044305	calyx of Held(GO:0044305)
0.1	11.0	GO:0016605	PML body(GO:0016605)
0.1	19.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	4.2	GO:0005771	multivesicular body(GO:0005771)
0.1	0.4	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	40.1	GO:0005925	focal adhesion(GO:0005925)
0.1	1.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	3.8	GO:0031594	neuromuscular junction(GO:0031594)
0.1	0.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.4	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	11.4	GO:0030658	transport vesicle membrane(GO:0030658)
0.0	2.1	GO:0005901	caveola(GO:0005901)
0.0	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	4.4	GO:0005912	adherens junction(GO:0005912)
0.0	0.3	GO:0042788	polysomal ribosome(GO:0042788)
0.0	6.3	GO:0005795	Golgi stack(GO:0005795)
0.0	2.6	GO:0005581	collagen trimer(GO:0005581)
0.0	1.1	GO:0000145	exocyst(GO:0000145)
0.0	0.8	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0044853	plasma membrane raft(GO:0044853)
0.0	2.8	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	5.3	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	3.0	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	1.2	GO:0043657	host(GO:0018995) host cell(GO:0043657)
0.0	0.2	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	19.2	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.2	9.7	GO:1904928	coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
3.2	19.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
2.9	11.6	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
2.9	11.4	GO:0005018	platelet-derived growth factor alpha-receptor activity(GO:0005018)
2.2	20.2	GO:0043237	laminin-1 binding(GO:0043237)
2.1	8.2	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
2.0	17.6	GO:0017018	myosin phosphatase activity(GO:0017018)
1.8	56.9	GO:0005212	structural constituent of eye lens(GO:0005212)
1.8	12.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
1.7	75.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
1.6	4.9	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
1.6	7.9	GO:0032038	myosin II heavy chain binding(GO:0032038)
1.5	63.8	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
1.4	12.6	GO:0030368	interleukin-17 receptor activity(GO:0030368)
1.4	4.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4	4.2	GO:0035379	carbon dioxide transmembrane transporter activity(GO:0035379)
1.4	30.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
1.4	45.9	GO:0005523	tropomyosin binding(GO:0005523)
1.3	13.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
1.3	12.7	GO:0031432	titin binding(GO:0031432)
1.2	12.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.2	4.7	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor beta-receptor activity(GO:0005019)
1.1	121.4	GO:0008307	structural constituent of muscle(GO:0008307)
1.1	12.1	GO:0001042	RNA polymerase I core binding(GO:0001042)
1.1	31.7	GO:0031005	filamin binding(GO:0031005)
1.1	16.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0	7.7	GO:0050682	AF-2 domain binding(GO:0050682)
0.9	3.7	GO:0038132	neuregulin binding(GO:0038132)
0.9	1.8	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.9	6.5	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.9	29.1	GO:0030506	ankyrin binding(GO:0030506)
0.9	6.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.9	8.1	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.9	13.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.8	24.6	GO:0043495	protein anchor(GO:0043495)
0.8	4.2	GO:0031013	troponin I binding(GO:0031013)
0.8	6.4	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.8	3.2	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.7	8.7	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7	7.7	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7	6.7	GO:0016015	morphogen activity(GO:0016015)
0.7	13.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6	2.5	GO:0004967	glucagon receptor activity(GO:0004967)
0.6	1.8	GO:0036361	racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.6	7.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.6	1.7	GO:0047536	2-aminoadipate transaminase activity(GO:0047536)
0.5	4.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.5	11.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.5	13.0	GO:0045294	alpha-catenin binding(GO:0045294)
0.5	4.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.5	2.9	GO:0042015	interleukin-20 binding(GO:0042015)
0.5	9.9	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.4	13.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.4	4.4	GO:0032190	acrosin binding(GO:0032190)
0.4	5.2	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.4	13.2	GO:0070064	proline-rich region binding(GO:0070064)
0.4	5.9	GO:0070700	BMP receptor binding(GO:0070700)
0.4	9.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.4	1.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
0.4	14.6	GO:0001968	fibronectin binding(GO:0001968)
0.4	1.2	GO:0003880	protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.4	3.6	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.4	6.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.4	14.3	GO:0001972	retinoic acid binding(GO:0001972)
0.4	2.6	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4	5.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.4	1.1	GO:0050333	thiamin-triphosphatase activity(GO:0050333)
0.3	1.4	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.3	2.3	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3	1.7	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3	1.0	GO:0047275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3	4.6	GO:0008430	selenium binding(GO:0008430)
0.3	3.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	3.2	GO:0019534	toxin transporter activity(GO:0019534)
0.3	2.2	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.3	2.8	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.3	1.2	GO:0035514	DNA demethylase activity(GO:0035514)
0.3	23.3	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3	1.4	GO:0004995	tachykinin receptor activity(GO:0004995)
0.3	10.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.3	3.6	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3	9.2	GO:0035497	cAMP response element binding(GO:0035497)
0.3	3.0	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3	1.4	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3	7.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.3	5.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.2	4.7	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.2	27.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	6.0	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	4.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.2	2.8	GO:0004969	histamine receptor activity(GO:0004969)
0.2	2.5	GO:0008432	JUN kinase binding(GO:0008432)
0.2	0.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.2	0.6	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.2	1.4	GO:0050733	RS domain binding(GO:0050733)
0.2	0.6	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.2	5.1	GO:0031404	chloride ion binding(GO:0031404)
0.2	17.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	5.5	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	1.6	GO:0031433	telethonin binding(GO:0031433)
0.2	13.2	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	1.4	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.7	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.2	10.2	GO:0030332	cyclin binding(GO:0030332)
0.2	0.8	GO:0010736	serum response element binding(GO:0010736)
0.2	3.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	6.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2	1.3	GO:0036122	BMP binding(GO:0036122)
0.2	40.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.2	6.4	GO:0051213	dioxygenase activity(GO:0051213)
0.2	1.6	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.2	0.9	GO:0034711	inhibin binding(GO:0034711)
0.2	8.7	GO:0005504	fatty acid binding(GO:0005504)
0.2	2.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	19.8	GO:0019838	growth factor binding(GO:0019838)
0.2	4.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	2.3	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.2	4.7	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	28.2	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	17.0	GO:0032947	protein complex scaffold(GO:0032947)
0.1	4.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	3.4	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	3.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	1.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	3.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	56.7	GO:0003924	GTPase activity(GO:0003924)
0.1	0.9	GO:0004331	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1	0.7	GO:0070573	metallodipeptidase activity(GO:0070573)
0.1	0.6	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	7.1	GO:0005158	insulin receptor binding(GO:0005158)
0.1	1.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	1.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	1.5	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.6	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.1	2.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	13.4	GO:0030165	PDZ domain binding(GO:0030165)
0.1	36.6	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	2.6	GO:0005112	Notch binding(GO:0005112)
0.1	3.8	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	1.1	GO:0004849	uridine kinase activity(GO:0004849)
0.1	5.8	GO:0016504	peptidase activator activity(GO:0016504)
0.1	39.8	GO:0008017	microtubule binding(GO:0008017)
0.1	5.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	1.7	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	11.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.8	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.6	GO:0046556	alpha-L-arabinofuranosidase activity(GO:0046556)
0.1	1.8	GO:0001054	RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1	0.3	GO:0015563	thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1	15.1	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.1	1.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	16.0	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.1	35.0	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1	2.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.3	GO:0034046	poly(G) binding(GO:0034046)
0.1	0.5	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	0.4	GO:0043532	angiostatin binding(GO:0043532)
0.1	1.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	4.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	2.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.2	GO:0047708	biotinidase activity(GO:0047708)
0.1	1.4	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	0.3	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.8	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	1.9	GO:0019894	kinesin binding(GO:0019894)
0.0	0.4	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.8	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.0	3.2	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	1.4	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	1.0	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.9	GO:0030507	spectrin binding(GO:0030507)
0.0	1.5	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	1.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	4.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.2	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	5.1	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.5	GO:0030955	potassium ion binding(GO:0030955)
0.0	1.0	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	1.7	GO:0019825	oxygen binding(GO:0019825)
0.0	0.8	GO:0000287	magnesium ion binding(GO:0000287)
0.0	0.8	GO:0008009	chemokine activity(GO:0008009)
0.0	0.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	4.9	GO:0008022	protein C-terminus binding(GO:0008022)
0.0	0.9	GO:0005549	odorant binding(GO:0005549)
0.0	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	8.3	GO:0003779	actin binding(GO:0003779)
0.0	0.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.6	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	8.1	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.6	GO:0016758	transferase activity, transferring hexosyl groups(GO:0016758)
0.0	0.4	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.5	GO:0005109	frizzled binding(GO:0005109)
0.0	1.5	GO:0003774	motor activity(GO:0003774)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.9	GO:0035326	enhancer binding(GO:0035326)
0.0	0.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	25.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	28.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6	24.1	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.5	29.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.5	19.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	12.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3	3.9	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.3	12.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	7.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.3	30.7	PID SHP2 PATHWAY	SHP2 signaling
0.3	33.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.3	4.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	25.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.3	31.0	PID NOTCH PATHWAY	Notch signaling pathway
0.2	10.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	21.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	17.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.2	17.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	10.3	NABA COLLAGENS	Genes encoding collagen proteins
0.2	17.1	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	4.7	ST GA12 PATHWAY	G alpha 12 Pathway
0.2	5.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.2	6.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.2	6.4	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	13.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	5.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	6.8	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	4.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.1	2.4	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	2.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	19.3	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	5.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	5.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	6.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	5.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	2.4	PID ARF 3PATHWAY	Arf1 pathway
0.1	2.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	3.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	23.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	1.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.1	2.9	PID FGF PATHWAY	FGF signaling pathway
0.1	1.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	3.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	2.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	16.2	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.6	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	5.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.9	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	10.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.9	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	1.4	PID RHOA REG PATHWAY	Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	82.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.1	144.5	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
1.0	36.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.9	33.9	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.7	19.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.6	25.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	3.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.6	25.7	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.6	16.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.6	14.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.5	15.1	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	18.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.4	5.8	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.4	3.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.4	16.8	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.4	1.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3	28.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.3	4.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	37.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	19.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	5.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.2	5.1	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	6.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	6.9	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.2	3.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	10.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.2	8.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	4.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	15.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	7.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	4.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	30.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.8	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.1	10.7	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	2.8	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	0.9	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	3.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	6.2	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	8.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	2.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.3	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	1.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	4.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	0.3	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	1.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	4.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	5.7	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.7	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	10.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	2.3	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	1.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.9	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	2.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	1.1	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	2.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.5	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport

Results for TEAD3_TEAD1

Z-value: 0.03

Motif logo

Transcription factors associated with TEAD3_TEAD1

Activity-expression correlation:

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: