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Illumina Body Map 2, young vs old

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Results for TEAD4

Z-value: 0.50

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Transcription factors associated with TEAD4

Gene Symbol Gene ID Gene Info
TEAD4
ENSG00000197905.4 TEA domain transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD4hg19_v2_chr12_+_3068466_30684960.431.3e-02Click!

Activity profile of TEAD4 motif

Sorted Z-values of TEAD4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_86268065 2.87 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr9_+_71944241 2.55 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr10_-_75410771 2.52 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr9_-_104249400 2.45 ENST00000374848.3
TMEM246
transmembrane protein 246
chr14_-_106791536 2.30 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr10_-_4285835 2.26 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr5_+_53751445 2.21 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr4_-_110723134 2.16 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr17_-_29624343 2.11 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr17_-_66951382 1.93 ENST00000586539.1
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_179672142 1.83 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr9_+_13446472 1.81 ENST00000428006.2
RP11-536O18.1
RP11-536O18.1
chr19_+_35630022 1.73 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr14_-_106586656 1.71 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr14_-_106725723 1.71 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr7_-_82073109 1.59 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_+_35630628 1.59 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr14_-_106518922 1.58 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr16_-_46797149 1.56 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr7_-_82073031 1.56 ENST00000356253.5
ENST00000423588.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_-_110723335 1.54 ENST00000394634.2
CFI
complement factor I
chr11_+_94439591 1.52 ENST00000299004.9
AMOTL1
angiomotin like 1
chr2_+_1418154 1.51 ENST00000423320.1
ENST00000382198.1
TPO
thyroid peroxidase
chr2_-_89513402 1.51 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr10_-_4285923 1.51 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr17_-_66951474 1.48 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_151395525 1.47 ENST00000439275.1
RND3
Rho family GTPase 3
chr15_+_80733570 1.45 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_+_169079823 1.45 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_79472365 1.42 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr2_-_151344172 1.40 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr19_+_35630344 1.38 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr17_+_4855053 1.38 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr16_+_33006369 1.37 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr4_-_110723194 1.37 ENST00000394635.3
CFI
complement factor I
chr2_+_238767517 1.36 ENST00000404910.2
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr17_+_32582293 1.36 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr1_-_178838404 1.33 ENST00000444255.1
ANGPTL1
angiopoietin-like 1
chr14_-_106845789 1.31 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr10_+_63808970 1.31 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_+_120056939 1.30 ENST00000307128.5
MYOZ2
myozenin 2
chr14_-_106622419 1.29 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr3_+_98216448 1.29 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr2_+_239047337 1.28 ENST00000409223.1
ENST00000305959.4
KLHL30
kelch-like family member 30
chr3_+_123813509 1.28 ENST00000460856.1
ENST00000240874.3
KALRN
kalirin, RhoGEF kinase
chr10_+_123923205 1.26 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr14_-_106758101 1.25 ENST00000390611.2
IGHV2-26
immunoglobulin heavy variable 2-26
chr4_+_41614909 1.25 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr12_-_91572278 1.24 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN
decorin
chr7_-_111428957 1.24 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr13_-_62001982 1.23 ENST00000409186.1
PCDH20
protocadherin 20
chr2_+_238768187 1.23 ENST00000254661.4
ENST00000409726.1
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr6_+_125540951 1.22 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr12_+_101869096 1.20 ENST00000551346.1
SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr12_-_91539918 1.19 ENST00000548218.1
DCN
decorin
chr2_+_223916862 1.18 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr2_-_158184211 1.17 ENST00000397283.2
ERMN
ermin, ERM-like protein
chr10_+_50507232 1.15 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr13_-_38172863 1.15 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr7_-_22234381 1.15 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chrX_-_33146477 1.15 ENST00000378677.2
DMD
dystrophin
chr10_+_50507181 1.15 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chrX_-_73061339 1.14 ENST00000602863.1
XIST
X inactive specific transcript (non-protein coding)
chr12_-_111358372 1.14 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr4_-_13546632 1.14 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr3_-_119379719 1.13 ENST00000493094.1
POPDC2
popeye domain containing 2
chr3_-_100565249 1.13 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr14_-_107049312 1.13 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr3_-_112356944 1.12 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr22_-_42765174 1.12 ENST00000432473.1
ENST00000412060.1
ENST00000424852.1
Z83851.1
Z83851.1
chr5_-_124081008 1.12 ENST00000306315.5
ZNF608
zinc finger protein 608
chr3_-_100566492 1.11 ENST00000528490.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr18_-_3220106 1.09 ENST00000356443.4
ENST00000400569.3
MYOM1
myomesin 1
chr18_-_3219847 1.08 ENST00000261606.7
MYOM1
myomesin 1
chr2_+_220299547 1.04 ENST00000312358.7
SPEG
SPEG complex locus
chr8_+_55370487 1.04 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chr10_-_61513201 1.03 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr3_+_132316081 1.02 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr2_-_188419078 1.01 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_+_41614720 1.00 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr5_-_10308125 1.00 ENST00000296658.3
CMBL
carboxymethylenebutenolidase homolog (Pseudomonas)
chr8_-_70745575 0.98 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr21_-_39870339 0.96 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr15_-_22448819 0.95 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr4_-_186732048 0.95 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr20_+_43160458 0.92 ENST00000372889.1
ENST00000372887.1
ENST00000372882.3
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr3_-_52486841 0.92 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr3_-_47932759 0.90 ENST00000441748.2
ENST00000335271.5
MAP4
microtubule-associated protein 4
chr2_-_211168332 0.89 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_+_12766583 0.89 ENST00000361985.2
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr5_+_38445641 0.89 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr11_+_120255997 0.88 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr6_-_56507586 0.88 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr2_-_188419200 0.87 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_123317116 0.87 ENST00000275162.5
CLVS2
clavesin 2
chr1_+_161676739 0.86 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr5_+_57878859 0.85 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr21_-_27423339 0.85 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr11_-_10590238 0.84 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr10_-_61513146 0.83 ENST00000430431.1
LINC00948
long intergenic non-protein coding RNA 948
chrX_-_15402498 0.83 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr6_-_45983549 0.81 ENST00000544153.1
CLIC5
chloride intracellular channel 5
chr15_-_20193370 0.80 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr8_+_67405438 0.76 ENST00000305454.3
C8orf46
chromosome 8 open reading frame 46
chr2_+_33683109 0.75 ENST00000437184.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_163038565 0.74 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chr5_-_88120151 0.74 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr11_-_10590118 0.72 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_-_14028488 0.70 ENST00000405358.4
ETV1
ets variant 1
chr6_-_42690312 0.70 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr1_-_102462565 0.69 ENST00000370103.4
OLFM3
olfactomedin 3
chr12_+_109554386 0.69 ENST00000338432.7
ACACB
acetyl-CoA carboxylase beta
chr14_-_75530693 0.68 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr5_-_41794313 0.68 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr7_-_14029283 0.67 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chrX_+_21392873 0.67 ENST00000379510.3
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr16_-_2155399 0.66 ENST00000567946.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr2_+_201987200 0.66 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr3_+_123813543 0.66 ENST00000360013.3
KALRN
kalirin, RhoGEF kinase
chr7_+_87563557 0.65 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr18_+_52258390 0.65 ENST00000321600.1
DYNAP
dynactin associated protein
chrX_+_21392529 0.64 ENST00000425654.2
ENST00000543067.1
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr7_+_37960163 0.64 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1
ependymin related 1
chr4_-_44450814 0.64 ENST00000360029.3
KCTD8
potassium channel tetramerization domain containing 8
chr10_+_5005445 0.61 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr4_-_186682716 0.59 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_134639235 0.58 ENST00000533224.1
SGK1
serum/glucocorticoid regulated kinase 1
chr7_+_150811705 0.58 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr3_+_63428982 0.58 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr11_+_57308979 0.57 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr5_-_41794663 0.56 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr17_+_79369249 0.55 ENST00000574717.2
RP11-1055B8.6
Uncharacterized protein
chr2_-_89459813 0.54 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr18_-_66569492 0.54 ENST00000579678.1
RP11-861L17.3
Uncharacterized protein
chr12_+_109569155 0.54 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr6_-_109330702 0.53 ENST00000356644.7
SESN1
sestrin 1
chr1_-_60392452 0.53 ENST00000371204.3
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr5_-_88120083 0.53 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr3_-_164875850 0.52 ENST00000472120.1
RP11-747D18.1
RP11-747D18.1
chr4_+_141264597 0.52 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr8_-_30002179 0.51 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr8_+_22225041 0.51 ENST00000289952.5
ENST00000524285.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_-_45983581 0.51 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr1_+_161676983 0.51 ENST00000367957.2
FCRLA
Fc receptor-like A
chr8_-_27115931 0.50 ENST00000523048.1
STMN4
stathmin-like 4
chr3_+_130279178 0.50 ENST00000358511.6
ENST00000453409.2
COL6A6
collagen, type VI, alpha 6
chr2_-_180610767 0.50 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr1_+_178310581 0.50 ENST00000462775.1
RASAL2
RAS protein activator like 2
chr2_-_119605253 0.50 ENST00000295206.6
EN1
engrailed homeobox 1
chr1_+_164528616 0.49 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr1_+_66458072 0.49 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_60223225 0.48 ENST00000524807.1
ENST00000345732.4
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr11_-_6440624 0.47 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr3_+_101546827 0.46 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr6_+_31638156 0.46 ENST00000409525.1
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chrX_-_10588595 0.46 ENST00000423614.1
ENST00000317552.4
MID1
midline 1 (Opitz/BBB syndrome)
chr3_-_142608001 0.46 ENST00000295992.3
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr19_+_37825526 0.45 ENST00000592768.1
ENST00000591417.1
ENST00000585623.1
ENST00000592168.1
ENST00000591391.1
ENST00000392153.3
ENST00000589392.1
ENST00000324411.4
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr15_-_65398647 0.45 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr19_+_37837185 0.44 ENST00000541583.2
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr11_-_101778665 0.44 ENST00000534527.1
ANGPTL5
angiopoietin-like 5
chr2_+_90060377 0.44 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr11_-_71639446 0.44 ENST00000534704.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr8_-_134511587 0.43 ENST00000523855.1
ENST00000523854.1
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr15_+_89164560 0.43 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr2_-_237150258 0.43 ENST00000330842.6
ASB18
ankyrin repeat and SOCS box containing 18
chr4_+_70861647 0.43 ENST00000246895.4
ENST00000381060.2
STATH
statherin
chr12_-_125401885 0.42 ENST00000542416.1
UBC
ubiquitin C
chr11_-_102595681 0.42 ENST00000236826.3
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr10_+_24528108 0.42 ENST00000438429.1
KIAA1217
KIAA1217
chr3_-_196987309 0.41 ENST00000453607.1
DLG1
discs, large homolog 1 (Drosophila)
chr18_+_3466248 0.41 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr8_+_67405755 0.40 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr4_-_39033963 0.40 ENST00000381938.3
TMEM156
transmembrane protein 156
chr2_-_231989808 0.40 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr5_+_154092396 0.39 ENST00000336314.4
LARP1
La ribonucleoprotein domain family, member 1
chr4_+_40337340 0.39 ENST00000310169.2
CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
chr21_-_33975547 0.39 ENST00000431599.1
C21orf59
chromosome 21 open reading frame 59
chr2_-_161056802 0.39 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr15_-_42343388 0.37 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr7_+_80267973 0.37 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr1_-_151798546 0.37 ENST00000356728.6
RORC
RAR-related orphan receptor C
chr2_-_136875712 0.37 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr7_-_45956856 0.37 ENST00000428530.1
IGFBP3
insulin-like growth factor binding protein 3
chr12_-_123011476 0.37 ENST00000528279.1
ENST00000344591.4
ENST00000526560.2
RSRC2
arginine/serine-rich coiled-coil 2
chr12_-_123011536 0.36 ENST00000331738.7
ENST00000354654.2
RSRC2
arginine/serine-rich coiled-coil 2
chr4_+_87928413 0.36 ENST00000544085.1
AFF1
AF4/FMR2 family, member 1
chr6_-_134638767 0.35 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_44550441 0.35 ENST00000420756.1
ENST00000444696.1
PREPL
prolyl endopeptidase-like
chr8_-_27115903 0.34 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr1_+_164529004 0.34 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr11_-_71639613 0.34 ENST00000528184.1
ENST00000528511.2
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chrX_+_21392553 0.34 ENST00000279451.4
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr12_-_76478446 0.34 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr12_-_49393092 0.34 ENST00000421952.2
DDN
dendrin
chr21_+_17214724 0.33 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr15_-_72563585 0.33 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr4_+_55096010 0.32 ENST00000503856.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_+_60223312 0.32 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
MS4A1
membrane-spanning 4-domains, subfamily A, member 1
chr16_+_30386098 0.32 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.7 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.5 1.5 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 1.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.4 3.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 3.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.3 1.0 GO:0061010 endodermal cell fate determination(GO:0007493) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.3 2.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.9 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.2 0.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 3.6 GO:0042908 xenobiotic transport(GO:0042908)
0.2 2.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.2 1.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.2 1.1 GO:1990523 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.2 1.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.5 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 0.8 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.2 0.7 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.2 2.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2 1.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 1.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 20.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.6 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 2.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.2 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 1.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.4 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.7 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 1.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 1.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 1.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:1903874 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.5 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.9 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 2.3 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.3 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 1.1 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.9 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.2 GO:0001824 blastocyst development(GO:0001824)
0.0 2.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.0 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.7 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 2.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 6.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 0.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 3.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 8.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 1.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.9 GO:0031673 H zone(GO:0031673)
0.1 4.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0002133 polycystin complex(GO:0002133)
0.1 1.3 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.3 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 1.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 0.2 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 3.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 6.4 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.6 2.6 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.3 1.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.3 3.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.7 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 1.3 GO:0051373 FATZ binding(GO:0051373)
0.2 1.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.2 1.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 1.8 GO:0031433 telethonin binding(GO:0031433)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 8.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 2.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 2.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 5.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.8 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 5.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 2.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 8.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 5.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.9 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0030552 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) cAMP binding(GO:0030552)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 4.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 5.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS