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Illumina Body Map 2, young vs old

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Results for TGIF1

Z-value: 0.01

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.16 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3450161_3450210-0.522.3e-03Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_88367299 6.25 ENST00000419482.2
ENST00000444564.2
SET and MYND domain containing 1
chr2_+_88367368 5.52 ENST00000438570.1
SET and MYND domain containing 1
chr19_-_45826125 4.53 ENST00000221476.3
creatine kinase, muscle
chr14_-_23904861 3.59 ENST00000355349.3
myosin, heavy chain 7, cardiac muscle, beta
chr22_-_36013368 3.50 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
myoglobin
chr12_+_101988627 3.46 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr2_-_172750733 3.46 ENST00000392592.4
ENST00000422440.2
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr13_+_76413852 3.28 ENST00000533809.2
LIM domain 7
chr1_-_11907829 3.28 ENST00000376480.3
natriuretic peptide A
chr6_+_41021027 3.15 ENST00000244669.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr12_+_101988774 2.96 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr6_-_33714667 2.85 ENST00000293756.4
inositol hexakisphosphate kinase 3
chr1_-_217250231 2.65 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr10_-_98116912 2.62 ENST00000536387.1
oligodendrocytic myelin paranodal and inner loop protein
chr6_-_33714752 2.51 ENST00000451316.1
inositol hexakisphosphate kinase 3
chr13_+_30002741 2.45 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr2_+_27505260 2.45 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr8_-_41522779 2.36 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chr1_+_6615241 2.33 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
taste receptor, type 1, member 1
chr2_+_166430619 2.28 ENST00000409420.1
cysteine-serine-rich nuclear protein 3
chr6_-_84418841 2.27 ENST00000369694.2
ENST00000195649.6
synaptosomal-associated protein, 91kDa
chr13_+_30002846 2.23 ENST00000542829.1
microtubule associated tumor suppressor candidate 2
chr7_+_95401851 2.22 ENST00000447467.2
dynein, cytoplasmic 1, intermediate chain 1
chr1_+_228395755 2.15 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr15_+_40532058 2.08 ENST00000260404.4
p21 protein (Cdc42/Rac)-activated kinase 6
chr7_+_95401877 2.07 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
dynein, cytoplasmic 1, intermediate chain 1
chr6_-_84418860 2.04 ENST00000521743.1
synaptosomal-associated protein, 91kDa
chr3_-_39234074 2.03 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
xin actin-binding repeat containing 1
chr2_-_152589670 1.95 ENST00000604864.1
ENST00000603639.1
nebulin
chr12_-_39837192 1.76 ENST00000361961.3
ENST00000395670.3
kinesin family member 21A
chr5_+_173472607 1.75 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr12_-_75603482 1.73 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr12_+_77718388 1.72 ENST00000550042.1
RP1-34H18.1
chr12_-_75603643 1.69 ENST00000549446.1
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr8_-_41522719 1.68 ENST00000335651.6
ankyrin 1, erythrocytic
chr11_-_84028180 1.63 ENST00000280241.8
discs, large homolog 2 (Drosophila)
chr20_+_1246908 1.57 ENST00000381873.3
ENST00000381867.1
syntaphilin
chr4_+_114066764 1.55 ENST00000511380.1
ankyrin 2, neuronal
chr6_-_84418432 1.53 ENST00000519825.1
ENST00000523484.2
synaptosomal-associated protein, 91kDa
chr2_-_71454185 1.53 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr3_-_47622282 1.52 ENST00000383738.2
ENST00000264723.4
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr8_-_107782463 1.48 ENST00000311955.3
actin-binding Rho activating protein
chr6_-_84418738 1.48 ENST00000519779.1
synaptosomal-associated protein, 91kDa
chr22_-_50523843 1.47 ENST00000535444.1
ENST00000431262.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_111781554 1.46 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr9_-_97356075 1.46 ENST00000375337.3
fructose-1,6-bisphosphatase 2
chr22_-_50523807 1.44 ENST00000442311.1
ENST00000538737.1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr20_-_9819479 1.42 ENST00000378423.1
ENST00000353224.5
p21 protein (Cdc42/Rac)-activated kinase 7
chr11_+_27076764 1.41 ENST00000525090.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_-_111781454 1.41 ENST00000533280.1
crystallin, alpha B
chr11_-_111781610 1.41 ENST00000525823.1
crystallin, alpha B
chr2_+_220436917 1.39 ENST00000243786.2
inhibin, alpha
chr17_+_33474826 1.39 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
unc-45 homolog B (C. elegans)
chrX_-_128788914 1.38 ENST00000429967.1
ENST00000307484.6
apelin
chr3_-_33686925 1.37 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr22_-_50523688 1.33 ENST00000450140.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr17_+_33474860 1.32 ENST00000394570.2
unc-45 homolog B (C. elegans)
chr1_+_205473784 1.30 ENST00000478560.1
ENST00000443813.2
cyclin-dependent kinase 18
chr19_-_55686399 1.28 ENST00000587067.1
synaptotagmin V
chr11_+_12132117 1.26 ENST00000256194.4
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr12_+_79371565 1.25 ENST00000551304.1
synaptotagmin I
chr6_-_119031228 1.25 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr2_-_211179883 1.24 ENST00000352451.3
myosin, light chain 1, alkali; skeletal, fast
chr7_-_150884332 1.23 ENST00000275838.1
ENST00000422024.1
ENST00000434669.1
ankyrin repeat and SOCS box containing 10
chr14_+_100150622 1.22 ENST00000261835.3
cytochrome P450, family 46, subfamily A, polypeptide 1
chr15_-_78112553 1.22 ENST00000562933.1
leucine rich repeat and Ig domain containing 1
chr22_-_50524298 1.22 ENST00000311597.5
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523760 1.22 ENST00000395876.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr3_+_178253993 1.21 ENST00000420517.2
ENST00000452583.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr5_+_141348640 1.20 ENST00000540015.1
ENST00000506938.1
ENST00000394514.2
ENST00000512565.1
ENST00000394515.3
ring finger protein 14
chr12_-_75603236 1.19 ENST00000540018.1
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr20_-_9819674 1.18 ENST00000378429.3
p21 protein (Cdc42/Rac)-activated kinase 7
chr5_+_141348721 1.16 ENST00000507163.1
ENST00000394519.1
ring finger protein 14
chr1_+_111889212 1.15 ENST00000369737.4
primary cilia formation
chr1_+_240177627 1.15 ENST00000447095.1
formin 2
chr2_+_29353520 1.14 ENST00000438819.1
CAP-GLY domain containing linker protein family, member 4
chr12_+_107078474 1.13 ENST00000552866.1
ENST00000229387.5
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_41481135 1.13 ENST00000528697.1
ENST00000530763.1
leucine rich repeat containing 4C
chr20_+_34802295 1.12 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr1_+_205473720 1.10 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
cyclin-dependent kinase 18
chr5_+_141348755 1.09 ENST00000506004.1
ENST00000507291.1
ring finger protein 14
chr6_-_114664180 1.09 ENST00000312719.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr1_+_197237352 1.08 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chr6_+_73076432 1.06 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr7_-_137028498 1.06 ENST00000393083.2
pleiotrophin
chr11_-_111794446 1.06 ENST00000527950.1
crystallin, alpha B
chr5_-_131330272 1.06 ENST00000379240.1
acyl-CoA synthetase long-chain family member 6
chr7_+_97361388 1.05 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr11_+_63870660 1.05 ENST00000246841.3
fibronectin leucine rich transmembrane protein 1
chr17_-_55911970 1.04 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3
chr8_+_102064237 1.04 ENST00000514926.1
RP11-302J23.1
chr1_-_39395165 1.03 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr1_+_111888890 1.03 ENST00000369738.4
primary cilia formation
chr5_-_131329918 1.03 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
acyl-CoA synthetase long-chain family member 6
chr2_+_166152283 1.02 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chr4_-_109683691 1.02 ENST00000512320.1
ENST00000510723.1
ethanolamine-phosphate phospho-lyase
chr12_-_87232644 1.01 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_+_113229452 1.01 ENST00000389385.4
rabphilin 3A homolog (mouse)
chr7_-_25702558 1.01 ENST00000423689.2
AC003090.1
chr5_-_36301984 1.01 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr7_-_137028534 1.00 ENST00000348225.2
pleiotrophin
chr1_-_190443931 1.00 ENST00000445957.2
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr2_+_136343904 0.99 ENST00000436436.1
R3H domain containing 1
chr5_+_143584814 0.98 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr8_+_99076750 0.98 ENST00000545282.1
chromosome 8 open reading frame 47
chr18_+_54318616 0.98 ENST00000254442.3
WD repeat domain 7
chr8_-_74495065 0.96 ENST00000523533.1
staufen double-stranded RNA binding protein 2
chr19_+_1452188 0.95 ENST00000587149.1
adenomatosis polyposis coli 2
chr9_+_134165063 0.95 ENST00000372264.3
phosphatidic acid phosphatase type 2 domain containing 3
chr1_+_74701062 0.95 ENST00000326637.3
TNNI3 interacting kinase
chr1_-_16344500 0.95 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
heat shock 27kDa protein family, member 7 (cardiovascular)
chr8_+_67039278 0.94 ENST00000276573.7
ENST00000350034.4
tripartite motif containing 55
chr12_+_78224667 0.93 ENST00000549464.1
neuron navigator 3
chr11_-_26743546 0.92 ENST00000280467.6
ENST00000396005.3
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr12_-_39836772 0.92 ENST00000541463.2
ENST00000361418.5
ENST00000544797.2
kinesin family member 21A
chr3_-_123168551 0.91 ENST00000462833.1
adenylate cyclase 5
chr5_+_43192311 0.91 ENST00000326035.2
NIM1 serine/threonine protein kinase
chr10_+_70748487 0.91 ENST00000361983.4
KIAA1279
chr1_+_203097407 0.91 ENST00000367235.1
adenosine A1 receptor
chr8_+_67039131 0.90 ENST00000315962.4
ENST00000353317.5
tripartite motif containing 55
chr5_-_132113063 0.90 ENST00000378719.2
septin 8
chr8_+_94929969 0.90 ENST00000517764.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr18_+_54318566 0.89 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr5_+_173472744 0.89 ENST00000521585.1
Neuron-specific protein family member 2
chr12_+_113229543 0.88 ENST00000447659.2
rabphilin 3A homolog (mouse)
chr3_+_35722844 0.88 ENST00000436702.1
ENST00000438071.1
cAMP-regulated phosphoprotein, 21kDa
chr13_-_48575376 0.88 ENST00000434484.1
succinate-CoA ligase, ADP-forming, beta subunit
chr9_+_134165195 0.88 ENST00000372261.1
phosphatidic acid phosphatase type 2 domain containing 3
chr3_+_35722487 0.87 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr2_+_58134756 0.86 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr2_+_201936707 0.86 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr9_-_130635741 0.86 ENST00000223836.10
adenylate kinase 1
chr4_-_44450814 0.86 ENST00000360029.3
potassium channel tetramerization domain containing 8
chr18_-_31802056 0.85 ENST00000538587.1
nucleolar protein 4
chr18_+_13611431 0.84 ENST00000587757.1
low density lipoprotein receptor class A domain containing 4
chr12_-_25348007 0.84 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
cancer susceptibility candidate 1
chr9_-_140142222 0.84 ENST00000344774.4
ENST00000388932.2
family with sequence similarity 166, member A
chr5_+_71014990 0.83 ENST00000296777.4
CART prepropeptide
chr19_+_51153045 0.83 ENST00000458538.1
chromosome 19 open reading frame 81
chr4_-_89205705 0.83 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr11_-_10920714 0.83 ENST00000533941.1
CTD-2003C8.2
chr14_-_73360796 0.83 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
D4, zinc and double PHD fingers, family 3
chrM_+_5824 0.83 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr5_+_141348598 0.82 ENST00000394520.2
ENST00000347642.3
ring finger protein 14
chr11_-_84028339 0.82 ENST00000398301.2
discs, large homolog 2 (Drosophila)
chr7_+_97361218 0.82 ENST00000319273.5
tachykinin, precursor 1
chr3_+_35722424 0.82 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chr6_+_24126350 0.82 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr11_-_31832862 0.81 ENST00000379115.4
paired box 6
chr5_-_132112921 0.81 ENST00000378721.4
ENST00000378701.1
septin 8
chr10_+_69869237 0.81 ENST00000373675.3
myopalladin
chr4_+_95916947 0.80 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr4_+_88896819 0.79 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr19_-_38714847 0.79 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr16_+_2198604 0.79 ENST00000210187.6
RAB26, member RAS oncogene family
chr5_-_132112907 0.79 ENST00000458488.2
septin 8
chr1_-_39407467 0.79 ENST00000540558.1
rhomboid, veinlet-like 2 (Drosophila)
chr10_-_24911746 0.78 ENST00000320481.6
Rho GTPase activating protein 21
chr5_+_125759140 0.78 ENST00000543198.1
GRAM domain containing 3
chr11_-_83393429 0.78 ENST00000426717.2
discs, large homolog 2 (Drosophila)
chr1_-_150978953 0.78 ENST00000493834.2
family with sequence similarity 63, member A
chr15_-_67351586 0.77 ENST00000558071.1
RP11-798K3.2
chr1_-_150979333 0.77 ENST00000312210.5
family with sequence similarity 63, member A
chr19_-_36643329 0.76 ENST00000589154.1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr2_+_115199876 0.76 ENST00000436732.1
ENST00000410059.1
dipeptidyl-peptidase 10 (non-functional)
chr10_-_75255668 0.75 ENST00000545874.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr18_-_31802282 0.75 ENST00000535475.1
nucleolar protein 4
chr11_-_118023594 0.75 ENST00000529878.1
sodium channel, voltage-gated, type IV, beta subunit
chr3_+_156807663 0.75 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
long intergenic non-protein coding RNA 881
chr10_+_123872483 0.74 ENST00000369001.1
transforming, acidic coiled-coil containing protein 2
chr17_-_10701241 0.74 ENST00000578763.1
long intergenic non-protein coding RNA 675
chr6_-_3227877 0.73 ENST00000259818.7
tubulin, beta 2B class IIb
chr4_-_114682364 0.73 ENST00000511664.1
calcium/calmodulin-dependent protein kinase II delta
chr16_-_3030407 0.72 ENST00000431515.2
ENST00000574385.1
ENST00000576268.1
ENST00000574730.1
ENST00000575632.1
ENST00000573944.1
ENST00000262300.8
protein kinase, membrane associated tyrosine/threonine 1
chr3_-_190580404 0.72 ENST00000442080.1
geminin coiled-coil domain containing
chr20_+_4667094 0.72 ENST00000424424.1
ENST00000457586.1
prion protein
chr8_+_99076509 0.72 ENST00000318528.3
chromosome 8 open reading frame 47
chr18_+_54318893 0.72 ENST00000593058.1
WD repeat domain 7
chr2_+_136343820 0.71 ENST00000410054.1
R3H domain containing 1
chr10_+_60028818 0.71 ENST00000333926.5
CDGSH iron sulfur domain 1
chr5_-_132113036 0.71 ENST00000378706.1
septin 8
chr8_+_30496078 0.70 ENST00000517349.1
small integral membrane protein 18
chr4_-_89205879 0.70 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr17_-_3417062 0.70 ENST00000570318.1
ENST00000541913.1
spermatogenesis associated 22
chr10_-_61469837 0.69 ENST00000395348.3
solute carrier family 16, member 9
chr4_-_46391367 0.69 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr2_-_179914760 0.69 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
coiled-coil domain containing 141
chr11_-_31832581 0.69 ENST00000379111.2
paired box 6
chr1_+_163038565 0.68 ENST00000421743.2
regulator of G-protein signaling 4
chr19_-_39735646 0.68 ENST00000413851.2
interferon, lambda 3
chrX_+_101380642 0.68 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr12_+_113229337 0.67 ENST00000552667.1
rabphilin 3A homolog (mouse)
chr1_+_170115142 0.67 ENST00000439373.2
methyltransferase like 11B
chr5_-_131330315 0.66 ENST00000419502.1
acyl-CoA synthetase long-chain family member 6
chr11_-_31832685 0.66 ENST00000438681.1
paired box 6
chr1_-_193075180 0.66 ENST00000367440.3
glutaredoxin 2
chr13_-_96329048 0.65 ENST00000606011.1
ENST00000499499.2
DNAJC3 antisense RNA 1 (head to head)
chr9_-_130637244 0.64 ENST00000373156.1
adenylate kinase 1
chr2_-_113594279 0.64 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr12_+_100041527 0.64 ENST00000324341.1
family with sequence similarity 71, member C

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.9 3.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.8 2.4 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.7 2.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.7 3.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.6 3.7 GO:0036309 protein localization to M-band(GO:0036309)
0.6 4.6 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.5 1.4 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.4 3.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 0.8 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.4 2.0 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.4 1.5 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.4 4.3 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 1.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.3 12.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 3.2 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 1.3 GO:0019417 sulfur oxidation(GO:0019417)
0.3 6.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.3 0.9 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.3 2.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 6.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.4 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.3 2.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 4.5 GO:0006600 creatine metabolic process(GO:0006600)
0.3 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 10.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.2 0.9 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 0.6 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 5.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.8 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 1.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.7 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.2 0.5 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 0.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 4.0 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 0.5 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 0.5 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 1.0 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.6 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.4 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 1.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.7 GO:0070541 response to platinum ion(GO:0070541)
0.1 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 1.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 2.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.2 GO:1903056 regulation of melanosome organization(GO:1903056)
0.1 0.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 1.6 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 4.3 GO:0046710 GDP metabolic process(GO:0046710)
0.1 0.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 2.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.2 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 3.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 2.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.3 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.7 GO:0042262 DNA protection(GO:0042262)
0.1 3.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.8 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0071233 cellular response to leucine(GO:0071233)
0.1 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.5 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.5 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 0.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.2 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.9 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 1.9 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.1 1.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.7 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.1 4.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 1.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.9 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 1.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 2.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 3.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.6 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 1.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.7 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 1.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.6 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 1.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 3.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.9 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 1.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0000819 sister chromatid segregation(GO:0000819)
0.0 0.2 GO:0030301 sterol transport(GO:0015918) cholesterol transport(GO:0030301)
0.0 0.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.3 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 5.3 GO:0097512 cardiac myofibril(GO:0097512)
0.3 10.0 GO:0032982 myosin filament(GO:0032982)
0.2 1.3 GO:1990769 proximal neuron projection(GO:1990769)
0.2 9.5 GO:0030673 axolemma(GO:0030673)
0.1 1.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 4.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.5 GO:0045202 synapse(GO:0045202)
0.1 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 3.7 GO:0031430 M band(GO:0031430)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 9.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 3.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 4.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.1 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 3.4 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 6.9 GO:0030018 Z disc(GO:0030018)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 2.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0030017 sarcomere(GO:0030017)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 5.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.5 2.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 4.5 GO:0004111 creatine kinase activity(GO:0004111)
0.4 3.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 9.8 GO:0031432 titin binding(GO:0031432)
0.4 1.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.4 1.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 3.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 2.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 2.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 1.4 GO:1903135 cupric ion binding(GO:1903135)
0.2 8.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 2.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 4.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 0.9 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 3.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.9 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 1.4 GO:0034711 inhibin binding(GO:0034711)
0.2 5.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 0.7 GO:0004325 ferrochelatase activity(GO:0004325)
0.2 0.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.6 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 4.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 5.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.6 GO:0008430 selenium binding(GO:0008430) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 1.1 GO:0050656 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 10.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 2.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.5 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 4.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 2.3 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.7 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 4.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 1.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 4.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.2 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.9 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.9 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 4.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.8 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 7.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 2.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 3.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 12.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 1.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 2.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 5.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 9.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 5.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 4.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 4.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 3.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions