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Illumina Body Map 2, young vs old

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Results for TP63

Z-value: 0.05

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
TP63
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189349162_1893493050.522.5e-03Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_2670066 4.05 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chrX_+_2670153 3.21 ENST00000509484.2
XG
Xg blood group
chr7_+_80267949 2.91 ENST00000482059.2
CD36
CD36 molecule (thrombospondin receptor)
chr11_+_18287721 2.76 ENST00000356524.4
SAA1
serum amyloid A1
chr11_+_18287801 2.74 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr19_+_18496957 2.71 ENST00000252809.3
GDF15
growth differentiation factor 15
chr20_-_52790512 2.55 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr1_+_17575584 2.54 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr1_-_209824643 2.45 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr9_+_124088860 2.45 ENST00000373806.1
GSN
gelsolin
chr7_+_80267973 2.45 ENST00000394788.3
ENST00000447544.2
CD36
CD36 molecule (thrombospondin receptor)
chr15_-_42448788 2.45 ENST00000382396.4
ENST00000397272.3
PLA2G4F
phospholipase A2, group IVF
chr10_-_88729200 2.38 ENST00000474994.2
MMRN2
multimerin 2
chr9_+_35906176 2.37 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr11_-_111782484 2.36 ENST00000533971.1
CRYAB
crystallin, alpha B
chr6_-_46922659 2.34 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr6_+_54711533 2.34 ENST00000306858.7
FAM83B
family with sequence similarity 83, member B
chr11_-_111782696 2.32 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr10_-_88729069 2.31 ENST00000609457.1
MMRN2
multimerin 2
chr1_-_153588334 2.28 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr11_+_393428 2.27 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr18_+_61143994 2.27 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_+_119616447 2.12 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr1_-_47655686 2.10 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr12_-_52887034 2.09 ENST00000330722.6
KRT6A
keratin 6A
chr1_-_201398985 2.09 ENST00000336092.4
TNNI1
troponin I type 1 (skeletal, slow)
chr11_-_75921780 2.05 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr15_+_74466744 2.03 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr13_-_78492955 1.97 ENST00000446573.1
EDNRB
endothelin receptor type B
chr11_-_10920714 1.94 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr19_-_17375527 1.93 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr13_-_78492927 1.93 ENST00000334286.5
EDNRB
endothelin receptor type B
chr9_+_71944241 1.88 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr13_+_23755127 1.87 ENST00000545013.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_+_120031264 1.86 ENST00000426426.1
TMEM233
transmembrane protein 233
chr10_-_90751038 1.84 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_+_51955831 1.82 ENST00000356218.4
FRMD6
FERM domain containing 6
chr3_+_132316081 1.81 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr15_-_89456630 1.80 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr12_-_52845910 1.79 ENST00000252252.3
KRT6B
keratin 6B
chr13_+_23755054 1.78 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr15_-_89456593 1.77 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chr2_+_234600253 1.76 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr11_+_111782934 1.76 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr11_+_111783450 1.74 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr19_+_35849362 1.74 ENST00000327809.4
FFAR3
free fatty acid receptor 3
chr3_+_138066539 1.72 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr8_+_33613265 1.72 ENST00000517292.1
RP11-317N12.1
RP11-317N12.1
chr15_+_101417919 1.70 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr19_-_5293243 1.69 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr13_+_23755099 1.63 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_-_15942503 1.54 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr20_+_57264187 1.51 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr16_+_66413128 1.49 ENST00000563425.2
CDH5
cadherin 5, type 2 (vascular endothelium)
chr2_+_217524323 1.49 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_121756809 1.48 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_151344172 1.44 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr15_-_90233907 1.43 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr11_+_76493294 1.42 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr11_+_62009653 1.36 ENST00000244926.3
SCGB1D2
secretoglobin, family 1D, member 2
chr1_-_117753540 1.36 ENST00000328189.3
ENST00000369458.3
VTCN1
V-set domain containing T cell activation inhibitor 1
chr5_-_169626104 1.35 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chr11_+_832804 1.34 ENST00000397420.3
ENST00000525718.1
CD151
CD151 molecule (Raph blood group)
chr1_+_86889769 1.32 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr12_-_88974236 1.31 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr6_-_150212029 1.29 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
RAET1E
retinoic acid early transcript 1E
chr17_-_34079897 1.26 ENST00000254466.6
ENST00000587565.1
GAS2L2
growth arrest-specific 2 like 2
chr19_+_35861831 1.26 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr17_+_21279509 1.26 ENST00000583088.1
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr16_+_82090028 1.24 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr7_-_72742085 1.23 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr16_-_67224002 1.23 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr22_+_31489344 1.22 ENST00000404574.1
SMTN
smoothelin
chr1_-_46089718 1.20 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17
coiled-coil domain containing 17
chr7_+_100466433 1.19 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr11_+_64073699 1.17 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr1_+_26485511 1.15 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr3_+_69915385 1.12 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr2_-_165698662 1.12 ENST00000194871.6
ENST00000445474.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr16_+_67197288 1.12 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chrX_-_153602991 1.11 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr12_-_6233828 1.11 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr16_-_68000717 1.11 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr3_+_69915363 1.10 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr3_-_149375783 1.10 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr11_+_1856034 1.08 ENST00000341958.3
SYT8
synaptotagmin VIII
chr19_-_5292781 1.07 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr12_-_55042140 1.07 ENST00000293371.6
ENST00000456047.2
DCD
dermcidin
chr15_+_55700741 1.05 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr11_+_27062272 1.05 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr2_+_69201705 1.03 ENST00000377938.2
GKN1
gastrokine 1
chr15_-_63448973 0.99 ENST00000462430.1
RPS27L
ribosomal protein S27-like
chr2_+_71127699 0.98 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr12_-_96184533 0.98 ENST00000343702.4
ENST00000344911.4
NTN4
netrin 4
chr19_+_35849723 0.98 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr15_+_41136216 0.98 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_-_50340996 0.96 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr4_-_145061788 0.95 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA
GYPB
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr19_+_15160130 0.94 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr16_+_19467772 0.94 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr20_-_6103666 0.94 ENST00000536936.1
FERMT1
fermitin family member 1
chr4_+_15376165 0.93 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr12_+_52306113 0.93 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr15_+_41136263 0.91 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr6_+_148663729 0.90 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr2_-_165698521 0.89 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr15_+_41136369 0.87 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chrX_-_153583257 0.87 ENST00000438732.1
FLNA
filamin A, alpha
chr20_+_61867235 0.85 ENST00000342412.6
ENST00000217169.3
BIRC7
baculoviral IAP repeat containing 7
chr7_-_1600433 0.84 ENST00000431208.1
TMEM184A
transmembrane protein 184A
chr1_-_94312706 0.83 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_118727781 0.83 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr5_-_156486120 0.82 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr1_+_152799949 0.82 ENST00000335123.2
LCE1A
late cornified envelope 1A
chr1_-_19229014 0.82 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr8_+_74206829 0.82 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr19_-_17375541 0.81 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr19_-_4717835 0.81 ENST00000599248.1
DPP9
dipeptidyl-peptidase 9
chr3_+_32148106 0.78 ENST00000425459.1
ENST00000431009.1
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr11_+_1049862 0.78 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr8_-_49833978 0.77 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr7_+_102389434 0.77 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr14_-_23904861 0.75 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr1_-_19229248 0.74 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr16_-_57837129 0.74 ENST00000562984.1
ENST00000564891.1
KIFC3
kinesin family member C3
chr4_+_186317133 0.73 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr2_-_96812751 0.73 ENST00000449242.1
AC012307.2
AC012307.2
chr14_+_24779340 0.72 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr5_-_42812143 0.72 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chr4_-_8160416 0.72 ENST00000505872.1
ENST00000447017.2
ENST00000341937.5
ENST00000361581.5
ABLIM2
actin binding LIM protein family, member 2
chr19_+_35862192 0.71 ENST00000597214.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr12_-_96184913 0.71 ENST00000538383.1
NTN4
netrin 4
chr19_-_47288162 0.69 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr7_+_79763271 0.69 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr4_-_87374330 0.69 ENST00000511328.1
ENST00000503911.1
MAPK10
mitogen-activated protein kinase 10
chr6_+_134210243 0.69 ENST00000367882.4
TCF21
transcription factor 21
chr1_+_236558694 0.68 ENST00000359362.5
EDARADD
EDAR-associated death domain
chr15_-_90233866 0.68 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr16_+_57653625 0.68 ENST00000567553.1
ENST00000565314.1
GPR56
G protein-coupled receptor 56
chr16_+_57653596 0.68 ENST00000568791.1
ENST00000570044.1
GPR56
G protein-coupled receptor 56
chr4_-_129209221 0.66 ENST00000512483.1
PGRMC2
progesterone receptor membrane component 2
chr19_-_19051103 0.66 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr15_+_86686953 0.65 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr6_+_18387570 0.63 ENST00000259939.3
RNF144B
ring finger protein 144B
chr20_+_34679725 0.63 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr18_+_34124507 0.62 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr8_-_74206133 0.62 ENST00000352983.2
RPL7
ribosomal protein L7
chr22_+_36044411 0.61 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr3_+_136676851 0.61 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr20_+_48807351 0.61 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_6591113 0.61 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr15_+_69857515 0.61 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr1_-_19229218 0.60 ENST00000432718.1
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr19_+_12175535 0.60 ENST00000550826.1
ZNF844
zinc finger protein 844
chr3_+_136676707 0.60 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr12_-_58159361 0.60 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chrX_+_152086373 0.60 ENST00000318529.8
ZNF185
zinc finger protein 185 (LIM domain)
chr17_-_74707037 0.58 ENST00000355797.3
ENST00000375036.2
ENST00000449428.2
MXRA7
matrix-remodelling associated 7
chr14_-_46185155 0.58 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr2_+_201987200 0.58 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr7_-_100287071 0.57 ENST00000275732.5
GIGYF1
GRB10 interacting GYF protein 1
chr16_-_57798253 0.57 ENST00000565270.1
KIFC3
kinesin family member C3
chr1_-_3528034 0.57 ENST00000356575.4
MEGF6
multiple EGF-like-domains 6
chr19_+_12175596 0.57 ENST00000441304.2
ZNF844
zinc finger protein 844
chr19_-_11688951 0.56 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr20_-_43743790 0.56 ENST00000307971.4
ENST00000372789.4
WFDC5
WAP four-disulfide core domain 5
chr19_-_11639931 0.55 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr19_-_11688500 0.55 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr5_+_162864575 0.55 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr9_+_139553306 0.55 ENST00000371699.1
EGFL7
EGF-like-domain, multiple 7
chr1_-_26197744 0.55 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr4_+_72204755 0.54 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr9_+_101569944 0.54 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr21_+_44313375 0.53 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr18_+_61144160 0.53 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr2_-_31361362 0.53 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr11_-_67397371 0.52 ENST00000376693.2
ENST00000301490.4
NUDT8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr7_-_3197888 0.52 ENST00000458648.1
AC091801.1
LOC392621; Uncharacterized protein
chr20_-_23669590 0.51 ENST00000217423.3
CST4
cystatin S
chr11_+_47608198 0.51 ENST00000356737.2
ENST00000538490.1
FAM180B
family with sequence similarity 180, member B
chr12_-_49488573 0.50 ENST00000266991.2
DHH
desert hedgehog
chr20_+_34894247 0.50 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr14_-_37642016 0.50 ENST00000331299.5
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr5_-_160365601 0.50 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr4_-_10023095 0.49 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr7_+_75024903 0.49 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr3_+_37441062 0.49 ENST00000426078.1
C3orf35
chromosome 3 open reading frame 35
chr17_-_28661065 0.47 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr5_-_180235755 0.47 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr5_-_42811986 0.47 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr12_+_120105558 0.46 ENST00000229328.5
ENST00000541640.1
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr15_-_55700522 0.46 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr13_-_96296944 0.46 ENST00000361396.2
ENST00000376829.2
DZIP1
DAZ interacting zinc finger protein 1
chr14_-_37641618 0.45 ENST00000555449.1
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr2_-_31361543 0.44 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr22_+_23040274 0.44 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr7_-_3198204 0.44 ENST00000402115.1
ENST00000403226.1
AC091801.1
LOC392621; Uncharacterized protein
chr17_-_4938712 0.43 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr19_+_45165545 0.43 ENST00000592472.1
ENST00000587729.1
ENST00000585657.1
ENST00000592789.1
ENST00000591979.1
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr16_+_56995762 0.42 ENST00000200676.3
ENST00000379780.2
CETP
cholesteryl ester transfer protein, plasma

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.9 2.8 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.8 3.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.7 2.7 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.7 2.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 2.1 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.5 2.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.5 2.5 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4 5.4 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 1.3 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.4 1.7 GO:0060166 olfactory pit development(GO:0060166)
0.4 1.5 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.4 4.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4 1.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 1.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 2.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.8 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.2 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.3 1.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 2.1 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.3 0.8 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 1.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.7 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.2 2.3 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.8 GO:0003383 apical constriction(GO:0003383)
0.2 1.0 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 4.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.7 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.7 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 3.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 0.9 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.2 2.4 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.0 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.4 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 1.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 1.8 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 2.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 5.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 3.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 2.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.8 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.7 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199)
0.1 0.4 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 2.6 GO:0007398 ectoderm development(GO:0007398)
0.1 2.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 1.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.0 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.5 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 1.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1 0.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.0 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0060174 limb bud formation(GO:0060174)
0.0 2.3 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.6 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.0 0.3 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 1.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 2.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.4 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 1.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.5 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 1.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 1.1 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 1.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0035936 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 1.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 5.6 GO:0055001 muscle cell development(GO:0055001)
0.0 0.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 1.1 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0051604 protein maturation(GO:0051604)
0.0 0.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 2.0 GO:0031523 Myb complex(GO:0031523)
0.3 1.0 GO:0036117 hyaluranon cable(GO:0036117)
0.3 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 0.8 GO:1990716 axonemal central apparatus(GO:1990716)
0.3 4.7 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.5 GO:0005610 laminin-5 complex(GO:0005610)
0.2 2.5 GO:0030478 actin cap(GO:0030478)
0.2 5.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 4.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 2.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 5.0 GO:0045095 keratin filament(GO:0045095)
0.0 6.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 3.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 2.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 2.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.5 2.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 2.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.5 5.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 2.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 0.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 1.0 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.2 3.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 1.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 2.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.7 GO:0043237 laminin-1 binding(GO:0043237)
0.2 2.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 1.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 2.5 GO:0045159 myosin II binding(GO:0045159)
0.1 4.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.4 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 1.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 5.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0004583 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 2.1 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0008494 translation activator activity(GO:0008494)
0.0 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 6.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 1.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.8 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.3 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.7 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 6.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 2.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.0 2.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.8 GO:0019956 chemokine binding(GO:0019956)
0.0 1.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.0 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 8.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 4.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 6.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 3.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 6.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 9.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 5.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 3.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.3 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 6.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport