ISMARA results: TWIST1

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Illumina Body Map 2, young vs old

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Results for TWIST1_SNAI1

Z-value: 0.93

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Transcription factors associated with TWIST1_SNAI1

Gene Symbol	Gene ID	Gene Info
TWIST1 Ensembl NCBI GeneCards UniProt	ENSG00000122691.8	twist family bHLH transcription factor 1
SNAI1 Ensembl NCBI GeneCards UniProt	ENSG00000124216.3	snail family transcriptional repressor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SNAI1	hg19_v2_chr20_+_48599506_48599536	0.32	7.8e-02	Click!
TWIST1	hg19_v2_chr7_-_19157248_19157295	0.22	2.2e-01	Click!

Activity profile of TWIST1_SNAI1 motif

Sorted Z-values of TWIST1_SNAI1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_47596287 Show fit	9.75	ENST00000263735.4	EPCAM Ensembl NCBI GeneCards UniProt Show fit	epithelial cell adhesion molecule
chr19_+_35532612 Show fit	9.74	ENST00000600390.1 ENST00000597419.1	HPN Ensembl NCBI GeneCards UniProt Show fit	hepsin
chr12_+_52626898 Show fit	9.59	ENST00000331817.5	KRT7 Ensembl NCBI GeneCards UniProt Show fit	keratin 7
chr4_-_77819002 Show fit	8.59	ENST00000334306.2	SOWAHB Ensembl NCBI GeneCards UniProt Show fit	sosondowah ankyrin repeat domain family member B
chr9_+_17579084 Show fit	8.29	ENST00000380607.4	SH3GL2 Ensembl NCBI GeneCards UniProt Show fit	SH3-domain GRB2-like 2
chrX_+_105969893 Show fit	8.29	ENST00000255499.2	RNF128 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 128, E3 ubiquitin protein ligase
chr16_+_4838393 Show fit	7.29	ENST00000589721.1	SMIM22 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 22
chr7_+_73242069 Show fit	6.78	ENST00000435050.1	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr19_+_6464243 Show fit	6.74	ENST00000600229.1 ENST00000356762.3	CRB3 Ensembl NCBI GeneCards UniProt Show fit	crumbs homolog 3 (Drosophila)
chr19_-_3480540 Show fit	6.61	ENST00000215531.4	C19orf77 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 77
chr7_+_73242490 Show fit	6.49	ENST00000431918.1	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr16_+_4845379 Show fit	6.08	ENST00000588606.1 ENST00000586005.1	SMIM22 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 22
chr19_-_10697895 Show fit	5.97	ENST00000591240.1 ENST00000589684.1 ENST00000591676.1 ENST00000250244.6 ENST00000590923.1	AP1M2 Ensembl NCBI GeneCards UniProt Show fit	adaptor-related protein complex 1, mu 2 subunit
chr8_+_120220561 Show fit	5.91	ENST00000276681.6	MAL2 Ensembl NCBI GeneCards UniProt Show fit	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr19_-_54676884 Show fit	5.73	ENST00000376591.4	TMC4 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel-like 4
chr19_-_54676846 Show fit	5.56	ENST00000301187.4	TMC4 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel-like 4
chr21_-_42879909 Show fit	5.55	ENST00000458356.1 ENST00000398585.3 ENST00000424093.1	TMPRSS2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protease, serine 2
chr3_+_53528659 Show fit	5.51	ENST00000350061.5	CACNA1D Ensembl NCBI GeneCards UniProt Show fit	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr17_+_52978185 Show fit	5.38	ENST00000572405.1 ENST00000572158.1 ENST00000540336.1 ENST00000572298.1 ENST00000536554.1 ENST00000575333.1 ENST00000570499.1 ENST00000572576.1	TOM1L1 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 (chicken)-like 1
chr17_+_37894179 Show fit	5.34	ENST00000577695.1 ENST00000309156.4 ENST00000309185.3	GRB7 Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor-bound protein 7
chr15_+_45722727 Show fit	5.25	ENST00000396650.2 ENST00000558435.1 ENST00000344300.3	C15orf48 Ensembl NCBI GeneCards UniProt Show fit	chromosome 15 open reading frame 48
chr19_+_7660716 Show fit	5.23	ENST00000160298.4 ENST00000446248.2	CAMSAP3 Ensembl NCBI GeneCards UniProt Show fit	calmodulin regulated spectrin-associated protein family, member 3
chr16_-_86542652 Show fit	5.23	ENST00000599749.1	FENDRR Ensembl NCBI GeneCards UniProt Show fit	FOXF1 adjacent non-coding developmental regulatory RNA
chr2_+_149894968 Show fit	5.14	ENST00000409642.3	LYPD6B Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 6B
chr18_-_71959159 Show fit	5.10	ENST00000494131.2 ENST00000397914.4 ENST00000340533.4	CYB5A Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type A (microsomal)
chr3_+_96533413 Show fit	5.04	ENST00000470610.2 ENST00000389672.5	EPHA6 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A6
chrX_+_70443050 Show fit	5.03	ENST00000361726.6	GJB1 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein, beta 1, 32kDa
chr21_-_42880075 Show fit	4.98	ENST00000332149.5	TMPRSS2 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protease, serine 2
chr2_+_149895207 Show fit	4.95	ENST00000409876.1	LYPD6B Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 6B
chr17_-_7165662 Show fit	4.92	ENST00000571881.2 ENST00000360325.7	CLDN7 Ensembl NCBI GeneCards UniProt Show fit	claudin 7
chr1_+_3385085 Show fit	4.87	ENST00000445297.1	ARHGEF16 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor (GEF) 16
chr15_+_50474385 Show fit	4.78	ENST00000267842.5	SLC27A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 27 (fatty acid transporter), member 2
chr16_-_3086927 Show fit	4.76	ENST00000572449.1	CCDC64B Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 64B
chr8_-_144815966 Show fit	4.74	ENST00000388913.3	FAM83H Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 83, member H
chr16_-_74808710 Show fit	4.72	ENST00000219368.3 ENST00000544337.1	FA2H Ensembl NCBI GeneCards UniProt Show fit	fatty acid 2-hydroxylase
chr15_+_50474412 Show fit	4.72	ENST00000380902.4	SLC27A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 27 (fatty acid transporter), member 2
chr21_-_43187231 Show fit	4.68	ENST00000332512.3 ENST00000352483.2	RIPK4 Ensembl NCBI GeneCards UniProt Show fit	receptor-interacting serine-threonine kinase 4
chr16_-_86542455 Show fit	4.65	ENST00000595886.1 ENST00000597578.1 ENST00000593604.1	FENDRR Ensembl NCBI GeneCards UniProt Show fit	FOXF1 adjacent non-coding developmental regulatory RNA
chr7_-_73184588 Show fit	4.63	ENST00000395145.2	CLDN3 Ensembl NCBI GeneCards UniProt Show fit	claudin 3
chr1_+_60280458 Show fit	4.38	ENST00000455990.1 ENST00000371208.3	HOOK1 Ensembl NCBI GeneCards UniProt Show fit	hook microtubule-tethering protein 1
chr2_-_219925189 Show fit	4.34	ENST00000295731.6	IHH Ensembl NCBI GeneCards UniProt Show fit	indian hedgehog
chr1_-_40782938 Show fit	4.32	ENST00000372736.3 ENST00000372748.3	COL9A2 Ensembl NCBI GeneCards UniProt Show fit	collagen, type IX, alpha 2
chr19_+_35609380 Show fit	4.22	ENST00000604621.1	FXYD3 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 3
chr16_+_68771128 Show fit	4.21	ENST00000261769.5 ENST00000422392.2	CDH1 Ensembl NCBI GeneCards UniProt Show fit	cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_95285896 Show fit	4.20	ENST00000446120.2 ENST00000271227.6 ENST00000527077.1 ENST00000529450.1	SLC44A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 44, member 3
chr1_-_156675535 Show fit	4.18	ENST00000368221.1	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr16_+_23194033 Show fit	4.08	ENST00000300061.2	SCNN1G Ensembl NCBI GeneCards UniProt Show fit	sodium channel, non-voltage-gated 1, gamma subunit
chr7_-_120497178 Show fit	4.07	ENST00000441017.1 ENST00000424710.1 ENST00000433758.1	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr15_+_41136586 Show fit	3.97	ENST00000431806.1	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr7_+_73245193 Show fit	3.97	ENST00000340958.2	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr11_+_27062860 Show fit	3.97	ENST00000528583.1	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_+_6464502 Show fit	3.93	ENST00000308243.7	CRB3 Ensembl NCBI GeneCards UniProt Show fit	crumbs homolog 3 (Drosophila)
chr18_+_47088401 Show fit	3.91	ENST00000261292.4 ENST00000427224.2 ENST00000580036.1	LIPG Ensembl NCBI GeneCards UniProt Show fit	lipase, endothelial
chr1_+_201979645 Show fit	3.91	ENST00000367284.5 ENST00000367283.3	ELF3 Ensembl NCBI GeneCards UniProt Show fit	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_+_1312675 Show fit	3.86	ENST00000296839.2	FOXQ1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box Q1
chr2_-_133427767 Show fit	3.86	ENST00000397463.2	LYPD1 Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 1
chr11_+_27062272 Show fit	3.84	ENST00000529202.1 ENST00000533566.1	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr3_+_96533621 Show fit	3.84	ENST00000542517.1 ENST00000506569.1	EPHA6 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A6
chr2_+_121493717 Show fit	3.84	ENST00000418323.1	GLI2 Ensembl NCBI GeneCards UniProt Show fit	GLI family zinc finger 2
chr1_-_156675368 Show fit	3.82	ENST00000368222.3	CRABP2 Ensembl NCBI GeneCards UniProt Show fit	cellular retinoic acid binding protein 2
chr10_+_18429671 Show fit	3.81	ENST00000282343.8	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium channel, voltage-dependent, beta 2 subunit
chr19_+_46367518 Show fit	3.80	ENST00000302177.2	FOXA3 Ensembl NCBI GeneCards UniProt Show fit	forkhead box A3
chr8_+_99076509 Show fit	3.77	ENST00000318528.3	C8orf47 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 47
chr19_-_1490398 Show fit	3.73	ENST00000588671.1 ENST00000300954.5	PCSK4 Ensembl NCBI GeneCards UniProt Show fit	proprotein convertase subtilisin/kexin type 4
chr11_+_27062502 Show fit	3.72	ENST00000263182.3	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr17_-_39684550 Show fit	3.71	ENST00000455635.1 ENST00000361566.3	KRT19 Ensembl NCBI GeneCards UniProt Show fit	keratin 19
chr17_-_39677971 Show fit	3.70	ENST00000393976.2	KRT15 Ensembl NCBI GeneCards UniProt Show fit	keratin 15
chr1_+_156030937 Show fit	3.69	ENST00000361084.5	RAB25 Ensembl NCBI GeneCards UniProt Show fit	RAB25, member RAS oncogene family
chr2_-_74669009 Show fit	3.68	ENST00000272430.5	RTKN Ensembl NCBI GeneCards UniProt Show fit	rhotekin
chr2_+_128177458 Show fit	3.66	ENST00000409048.1 ENST00000422777.3	PROC Ensembl NCBI GeneCards UniProt Show fit	protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_14772810 Show fit	3.64	ENST00000295092.2 ENST00000331243.4	FAM84A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 84, member A
chr17_+_52978156 Show fit	3.64	ENST00000348161.4	TOM1L1 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 (chicken)-like 1
chr6_-_10419871 Show fit	3.63	ENST00000319516.4	TFAP2A Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr7_-_1595871 Show fit	3.62	ENST00000319010.5	TMEM184A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 184A
chr19_+_38755042 Show fit	3.61	ENST00000301244.7	SPINT2 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type, 2
chr11_+_1855645 Show fit	3.54	ENST00000381968.3 ENST00000381978.3	SYT8 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin VIII
chr9_+_35673853 Show fit	3.52	ENST00000378357.4	CA9 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase IX
chr15_+_67547163 Show fit	3.52	ENST00000335894.4	IQCH Ensembl NCBI GeneCards UniProt Show fit	IQ motif containing H
chr19_+_45281118 Show fit	3.50	ENST00000270279.3 ENST00000341505.4	CBLC Ensembl NCBI GeneCards UniProt Show fit	Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr10_+_122216316 Show fit	3.49	ENST00000398250.1 ENST00000439221.1 ENST00000398248.1	PPAPDC1A Ensembl NCBI GeneCards UniProt Show fit	phosphatidic acid phosphatase type 2 domain containing 1A
chr6_-_30043539 Show fit	3.49	ENST00000376751.3 ENST00000244360.6	RNF39 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 39
chr11_-_130298888 Show fit	3.48	ENST00000257359.6	ADAMTS8 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr12_-_113574028 Show fit	3.39	ENST00000546530.1 ENST00000261729.5	RASAL1 Ensembl NCBI GeneCards UniProt Show fit	RAS protein activator like 1 (GAP1 like)
chr7_-_50132860 Show fit	3.38	ENST00000046087.2	ZPBP Ensembl NCBI GeneCards UniProt Show fit	zona pellucida binding protein
chr1_-_201368707 Show fit	3.33	ENST00000391967.2	LAD1 Ensembl NCBI GeneCards UniProt Show fit	ladinin 1
chr3_-_93747425 Show fit	3.31	ENST00000315099.2	STX19 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 19
chr7_-_122526499 Show fit	3.30	ENST00000412584.2	CADPS2 Ensembl NCBI GeneCards UniProt Show fit	Ca++-dependent secretion activator 2
chr4_+_166300084 Show fit	3.30	ENST00000402744.4	CPE Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase E
chr14_-_94789663 Show fit	3.29	ENST00000557225.1 ENST00000341584.3	SERPINA6 Ensembl NCBI GeneCards UniProt Show fit	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr10_-_82049424 Show fit	3.26	ENST00000372213.3	MAT1A Ensembl NCBI GeneCards UniProt Show fit	methionine adenosyltransferase I, alpha
chr9_+_101569944 Show fit	3.25	ENST00000375011.3	GALNT12 Ensembl NCBI GeneCards UniProt Show fit	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr12_+_53342625 Show fit	3.24	ENST00000388837.2 ENST00000550600.1 ENST00000388835.3	KRT18 Ensembl NCBI GeneCards UniProt Show fit	keratin 18
chr19_-_7939319 Show fit	3.23	ENST00000539422.1	CTD-3193O13.9 Ensembl NCBI GeneCards UniProt Show fit	Protein FLJ22184
chr2_+_27665232 Show fit	3.20	ENST00000543753.1 ENST00000288873.3	KRTCAP3 Ensembl NCBI GeneCards UniProt Show fit	keratinocyte associated protein 3
chr9_-_140142222 Show fit	3.19	ENST00000344774.4 ENST00000388932.2	FAM166A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 166, member A
chr2_+_205410516 Show fit	3.16	ENST00000406610.2 ENST00000462231.1	PARD3B Ensembl NCBI GeneCards UniProt Show fit	par-3 family cell polarity regulator beta
chr11_-_119993979 Show fit	3.14	ENST00000524816.3 ENST00000525327.1	TRIM29 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 29
chr18_-_47721447 Show fit	3.12	ENST00000285039.7	MYO5B Ensembl NCBI GeneCards UniProt Show fit	myosin VB
chr19_+_751122 Show fit	3.11	ENST00000215582.6	MISP Ensembl NCBI GeneCards UniProt Show fit	mitotic spindle positioning
chr6_+_159291090 Show fit	3.10	ENST00000367073.4 ENST00000608817.1	C6orf99 Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 99
chr19_+_49055332 Show fit	3.10	ENST00000201586.2	SULT2B1 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family, cytosolic, 2B, member 1
chr1_+_35247859 Show fit	3.05	ENST00000373362.3	GJB3 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein, beta 3, 31kDa
chr1_+_6615241 Show fit	3.04	ENST00000333172.6 ENST00000328191.4 ENST00000351136.3	TAS1R1 Ensembl NCBI GeneCards UniProt Show fit	taste receptor, type 1, member 1
chr5_+_63461642 Show fit	3.01	ENST00000296615.6 ENST00000381081.2 ENST00000389100.4	RNF180 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 180
chr15_+_41136734 Show fit	3.01	ENST00000568580.1	SPINT1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type 1
chr5_-_147211226 Show fit	2.99	ENST00000296695.5	SPINK1 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kazal type 1
chr4_+_106816592 Show fit	2.99	ENST00000379987.2 ENST00000453617.2 ENST00000427316.2 ENST00000514622.1 ENST00000305572.8	NPNT Ensembl NCBI GeneCards UniProt Show fit	nephronectin
chr9_+_133884469 Show fit	2.99	ENST00000361069.4	LAMC3 Ensembl NCBI GeneCards UniProt Show fit	laminin, gamma 3
chr12_+_50355647 Show fit	2.97	ENST00000293599.6	AQP5 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 5
chr1_+_6508100 Show fit	2.97	ENST00000461727.1	ESPN Ensembl NCBI GeneCards UniProt Show fit	espin
chr9_+_103790991 Show fit	2.93	ENST00000374874.3	LPPR1 Ensembl NCBI GeneCards UniProt Show fit	Lipid phosphate phosphatase-related protein type 1
chr7_-_50132801 Show fit	2.92	ENST00000419417.1	ZPBP Ensembl NCBI GeneCards UniProt Show fit	zona pellucida binding protein
chr2_-_154335300 Show fit	2.90	ENST00000325926.3	RPRM Ensembl NCBI GeneCards UniProt Show fit	reprimo, TP53 dependent G2 arrest mediator candidate
chr1_-_201368653 Show fit	2.87	ENST00000367313.3	LAD1 Ensembl NCBI GeneCards UniProt Show fit	ladinin 1
chr16_+_84402098 Show fit	2.86	ENST00000262429.4 ENST00000416219.2	ATP2C2 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, type 2C, member 2
chr19_+_55795493 Show fit	2.85	ENST00000309383.1	BRSK1 Ensembl NCBI GeneCards UniProt Show fit	BR serine/threonine kinase 1
chr11_-_117667806 Show fit	2.80	ENST00000527706.1 ENST00000321322.6	DSCAML1 Ensembl NCBI GeneCards UniProt Show fit	Down syndrome cell adhesion molecule like 1
chr16_+_68679193 Show fit	2.78	ENST00000581171.1	CDH3 Ensembl NCBI GeneCards UniProt Show fit	cadherin 3, type 1, P-cadherin (placental)
chr9_-_112083229 Show fit	2.78	ENST00000374566.3 ENST00000374557.4	EPB41L4B Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 4B
chr11_+_71903169 Show fit	2.75	ENST00000393676.3	FOLR1 Ensembl NCBI GeneCards UniProt Show fit	folate receptor 1 (adult)
chr5_+_76506706 Show fit	2.75	ENST00000340978.3 ENST00000346042.3 ENST00000264917.5 ENST00000342343.4 ENST00000333194.4	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr2_+_159651821 Show fit	2.75	ENST00000309950.3 ENST00000409042.1	DAPL1 Ensembl NCBI GeneCards UniProt Show fit	death associated protein-like 1
chr4_+_106816644 Show fit	2.74	ENST00000506666.1 ENST00000503451.1	NPNT Ensembl NCBI GeneCards UniProt Show fit	nephronectin
chr19_-_49118067 Show fit	2.73	ENST00000593772.1	FAM83E Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 83, member E
chr4_-_177116772 Show fit	2.71	ENST00000280191.2	SPATA4 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 4
chr6_+_159290917 Show fit	2.71	ENST00000367072.1	C6orf99 Ensembl NCBI GeneCards UniProt Show fit	chromosome 6 open reading frame 99
chr12_-_113573495 Show fit	2.69	ENST00000446861.3	RASAL1 Ensembl NCBI GeneCards UniProt Show fit	RAS protein activator like 1 (GAP1 like)
chr17_-_42345487 Show fit	2.69	ENST00000262418.6	SLC4A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr20_-_60942361 Show fit	2.68	ENST00000252999.3	LAMA5 Ensembl NCBI GeneCards UniProt Show fit	laminin, alpha 5
chr2_+_27665289 Show fit	2.67	ENST00000407293.1	KRTCAP3 Ensembl NCBI GeneCards UniProt Show fit	keratinocyte associated protein 3
chr5_+_170288856 Show fit	2.67	ENST00000523189.1	RANBP17 Ensembl NCBI GeneCards UniProt Show fit	RAN binding protein 17
chr17_-_39258461 Show fit	2.67	ENST00000440582.1	KRTAP4-16P Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 4-16, pseudogene
chr1_-_57285038 Show fit	2.66	ENST00000343433.6	C1orf168 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 168
chr17_+_79989937 Show fit	2.65	ENST00000580965.1	RAC3 Ensembl NCBI GeneCards UniProt Show fit	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_+_95286151 Show fit	2.65	ENST00000467909.1 ENST00000422520.2 ENST00000532427.1	SLC44A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 44, member 3
chr19_+_38755237 Show fit	2.61	ENST00000587516.1	SPINT2 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755203 Show fit	2.61	ENST00000587090.1 ENST00000454580.3	SPINT2 Ensembl NCBI GeneCards UniProt Show fit	serine peptidase inhibitor, Kunitz type, 2
chr7_+_70597109 Show fit	2.60	ENST00000333538.5	WBSCR17 Ensembl NCBI GeneCards UniProt Show fit	Williams-Beuren syndrome chromosome region 17
chr19_+_36359341 Show fit	2.59	ENST00000221891.4	APLP1 Ensembl NCBI GeneCards UniProt Show fit	amyloid beta (A4) precursor-like protein 1
chrX_-_71525742 Show fit	2.58	ENST00000450875.1 ENST00000417400.1 ENST00000431381.1 ENST00000445983.1	CITED1 Ensembl NCBI GeneCards UniProt Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr3_-_50383096 Show fit	2.56	ENST00000442887.1 ENST00000360165.3	ZMYND10 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, MYND-type containing 10
chr17_+_52978107 Show fit	2.56	ENST00000445275.2	TOM1L1 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 (chicken)-like 1
chr11_-_64612041 Show fit	2.52	ENST00000342711.5	CDC42BPG Ensembl NCBI GeneCards UniProt Show fit	CDC42 binding protein kinase gamma (DMPK-like)
chr17_+_8243154 Show fit	2.52	ENST00000328248.2 ENST00000584943.1	ODF4 Ensembl NCBI GeneCards UniProt Show fit	outer dense fiber of sperm tails 4
chr1_-_207119738 Show fit	2.49	ENST00000356495.4	PIGR Ensembl NCBI GeneCards UniProt Show fit	polymeric immunoglobulin receptor
chr2_+_128177253 Show fit	2.49	ENST00000427769.1	PROC Ensembl NCBI GeneCards UniProt Show fit	protein C (inactivator of coagulation factors Va and VIIIa)
chr1_+_54359854 Show fit	2.49	ENST00000361921.3 ENST00000322679.6 ENST00000532493.1 ENST00000525202.1 ENST00000524406.1 ENST00000388876.3	DIO1 Ensembl NCBI GeneCards UniProt Show fit	deiodinase, iodothyronine, type I
chr8_-_53477968 Show fit	2.48	ENST00000523939.1 ENST00000358543.4	FAM150A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 150, member A
chr1_-_209979465 Show fit	2.47	ENST00000542854.1	IRF6 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 6
chr19_+_3708376 Show fit	2.47	ENST00000539908.2	TJP3 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 3
chr1_-_209979375 Show fit	2.46	ENST00000367021.3	IRF6 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 6
chr5_-_135528822 Show fit	2.46	ENST00000607574.1	AC009014.3 Ensembl NCBI GeneCards UniProt Show fit	AC009014.3
chr6_-_132722604 Show fit	2.46	ENST00000392401.3 ENST00000367963.3	MOXD1 Ensembl NCBI GeneCards UniProt Show fit	monooxygenase, DBH-like 1
chr9_+_74764278 Show fit	2.45	ENST00000238018.4 ENST00000376989.3	GDA Ensembl NCBI GeneCards UniProt Show fit	guanine deaminase
chr17_-_39780819 Show fit	2.44	ENST00000311208.8	KRT17 Ensembl NCBI GeneCards UniProt Show fit	keratin 17
chr14_-_67878917 Show fit	2.42	ENST00000216446.4	PLEK2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin 2
chr11_-_70963538 Show fit	2.40	ENST00000413503.1	SHANK2 Ensembl NCBI GeneCards UniProt Show fit	SH3 and multiple ankyrin repeat domains 2
chr12_-_95942563 Show fit	2.40	ENST00000549639.1 ENST00000551837.1	USP44 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 44
chr2_+_205410723 Show fit	2.36	ENST00000358768.2 ENST00000351153.1 ENST00000349953.3	PARD3B Ensembl NCBI GeneCards UniProt Show fit	par-3 family cell polarity regulator beta
chr5_+_169532896 Show fit	2.35	ENST00000306268.6 ENST00000449804.2	FOXI1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box I1
chr2_+_234621551 Show fit	2.34	ENST00000608381.1 ENST00000373414.3	UGT1A1 Ensembl NCBI GeneCards UniProt Show fit UGT1A5 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5
chr5_-_54281407 Show fit	2.33	ENST00000381403.4	ESM1 Ensembl NCBI GeneCards UniProt Show fit	endothelial cell-specific molecule 1
chr18_+_29078131 Show fit	2.33	ENST00000585206.1	DSG2 Ensembl NCBI GeneCards UniProt Show fit	desmoglein 2
chr20_-_62103862 Show fit	2.32	ENST00000344462.4 ENST00000357249.2 ENST00000359125.2 ENST00000360480.3 ENST00000370224.1 ENST00000344425.5 ENST00000354587.3 ENST00000359689.1	KCNQ2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel, KQT-like subfamily, member 2
chr11_+_111789580 Show fit	2.31	ENST00000278601.5	C11orf52 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 52
chr17_-_46703826 Show fit	2.31	ENST00000550387.1 ENST00000311177.5	HOXB9 Ensembl NCBI GeneCards UniProt Show fit	homeobox B9
chr6_-_3227877 Show fit	2.30	ENST00000259818.7	TUBB2B Ensembl NCBI GeneCards UniProt Show fit	tubulin, beta 2B class IIb
chr7_+_89874483 Show fit	2.30	ENST00000389297.4 ENST00000316089.8	C7orf63 Ensembl NCBI GeneCards UniProt Show fit	chromosome 7 open reading frame 63
chr18_+_29077990 Show fit	2.28	ENST00000261590.8	DSG2 Ensembl NCBI GeneCards UniProt Show fit	desmoglein 2
chr17_-_7197881 Show fit	2.26	ENST00000007699.5	YBX2 Ensembl NCBI GeneCards UniProt Show fit	Y box binding protein 2
chr6_+_22569784 Show fit	2.26	ENST00000510882.2	HDGFL1 Ensembl NCBI GeneCards UniProt Show fit	hepatoma derived growth factor-like 1
chr8_+_144821557 Show fit	2.23	ENST00000534398.1	FAM83H-AS1 Ensembl NCBI GeneCards UniProt Show fit	FAM83H antisense RNA 1 (head to head)
chr8_+_144161874 Show fit	2.23	ENST00000562505.1	RP11-520P18.5 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr6_-_31138439 Show fit	2.21	ENST00000259915.8	POU5F1 Ensembl NCBI GeneCards UniProt Show fit	POU class 5 homeobox 1
chr1_+_31885963 Show fit	2.21	ENST00000373709.3	SERINC2 Ensembl NCBI GeneCards UniProt Show fit	serine incorporator 2
chr17_-_78450398 Show fit	2.20	ENST00000306773.4	NPTX1 Ensembl NCBI GeneCards UniProt Show fit	neuronal pentraxin I
chr3_+_119421849 Show fit	2.16	ENST00000273390.5 ENST00000463700.1	MAATS1 Ensembl NCBI GeneCards UniProt Show fit	MYCBP-associated, testis expressed 1
chr5_-_42811986 Show fit	2.15	ENST00000511224.1 ENST00000507920.1 ENST00000510965.1	SEPP1 Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P, plasma, 1
chr6_-_28554977 Show fit	2.14	ENST00000452236.2	SCAND3 Ensembl NCBI GeneCards UniProt Show fit	SCAN domain containing 3
chrX_+_72223352 Show fit	2.14	ENST00000373521.2 ENST00000538388.1	PABPC1L2B Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 1-like 2B
chr11_+_7273181 Show fit	2.13	ENST00000318881.6	SYT9 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin IX
chr7_+_154002189 Show fit	2.13	ENST00000332007.3	DPP6 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl-peptidase 6
chr2_+_115919049 Show fit	2.12	ENST00000393147.2	DPP10 Ensembl NCBI GeneCards UniProt Show fit	dipeptidyl-peptidase 10 (non-functional)
chr5_+_68788594 Show fit	2.11	ENST00000396442.2 ENST00000380766.2	OCLN Ensembl NCBI GeneCards UniProt Show fit	occludin
chr5_-_132113083 Show fit	2.11	ENST00000296873.7	SEPT8 Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr9_-_116861337 Show fit	2.11	ENST00000374118.3	KIF12 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 12
chr7_-_142583506 Show fit	2.10	ENST00000359396.3	TRPV6 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel, subfamily V, member 6
chr17_+_37894570 Show fit	2.09	ENST00000394211.3	GRB7 Ensembl NCBI GeneCards UniProt Show fit	growth factor receptor-bound protein 7
chr10_+_116853091 Show fit	2.08	ENST00000526946.1	ATRNL1 Ensembl NCBI GeneCards UniProt Show fit	attractin-like 1
chr6_+_31950150 Show fit	2.07	ENST00000537134.1	C4A Ensembl NCBI GeneCards UniProt Show fit	complement component 4A (Rodgers blood group)
chr1_-_47655686 Show fit	2.06	ENST00000294338.2	PDZK1IP1 Ensembl NCBI GeneCards UniProt Show fit	PDZK1 interacting protein 1
chr14_+_67999999 Show fit	2.06	ENST00000329153.5	PLEKHH1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr11_+_6260298 Show fit	2.06	ENST00000379936.2	CNGA4 Ensembl NCBI GeneCards UniProt Show fit	cyclic nucleotide gated channel alpha 4
chr19_-_36499521 Show fit	2.05	ENST00000397428.3 ENST00000503121.1 ENST00000340477.5 ENST00000324444.3 ENST00000490730.1	SYNE4 Ensembl NCBI GeneCards UniProt Show fit	spectrin repeat containing, nuclear envelope family member 4
chr16_+_4838412 Show fit	2.04	ENST00000589327.1	SMIM22 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 22
chr4_-_16085340 Show fit	2.04	ENST00000508167.1	PROM1 Ensembl NCBI GeneCards UniProt Show fit	prominin 1
chr12_-_49259643 Show fit	2.02	ENST00000309739.5	RND1 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 1
chr17_+_18280976 Show fit	2.01	ENST00000399134.4	EVPLL Ensembl NCBI GeneCards UniProt Show fit	envoplakin-like
chr11_+_394196 Show fit	2.00	ENST00000331563.2 ENST00000531857.1	PKP3 Ensembl NCBI GeneCards UniProt Show fit	plakophilin 3
chr17_+_73521763 Show fit	2.00	ENST00000167462.5 ENST00000375227.4 ENST00000392550.3 ENST00000578363.1 ENST00000579392.1	LLGL2 Ensembl NCBI GeneCards UniProt Show fit	lethal giant larvae homolog 2 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of TWIST1_SNAI1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	15.5	GO:0097195	pilomotor reflex(GO:0097195)
1.9	9.5	GO:0097089	methyl-branched fatty acid metabolic process(GO:0097089)
1.8	1.8	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.5	6.1	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
1.5	6.0	GO:0032771	regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
1.4	4.3	GO:0016539	intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.3	5.4	GO:0010983	positive regulation of high-density lipoprotein particle clearance(GO:0010983)
1.3	9.4	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.3	3.8	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
1.3	8.8	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.1	3.2	GO:0043000	Golgi to plasma membrane CFTR protein transport(GO:0043000)
1.0	4.0	GO:1902161	positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.9	2.8	GO:0061713	neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.9	11.5	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.9	0.9	GO:0072054	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.8	3.3	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.8	2.5	GO:0006147	guanine catabolic process(GO:0006147)
0.8	3.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.8	10.5	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.8	4.0	GO:2000768	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.8	3.1	GO:0000103	sulfate assimilation(GO:0000103)
0.8	8.5	GO:0016191	synaptic vesicle uncoating(GO:0016191)
0.8	28.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.7	2.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.7	3.6	GO:0003409	optic cup structural organization(GO:0003409)
0.7	10.6	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.7	3.3	GO:0030070	insulin processing(GO:0030070)
0.6	1.9	GO:0052314	phytoalexin metabolic process(GO:0052314)
0.6	8.6	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.6	6.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.6	2.4	GO:0031346	positive regulation of cell projection organization(GO:0031346)
0.6	1.8	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6	1.8	GO:0035566	regulation of metanephros size(GO:0035566)
0.6	3.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.6	4.7	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.6	5.3	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.6	1.2	GO:0060061	Spemann organizer formation(GO:0060061)
0.6	2.3	GO:0009386	translational attenuation(GO:0009386)
0.5	5.5	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.5	3.7	GO:0032185	septin cytoskeleton organization(GO:0032185)
0.5	1.6	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.5	2.6	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.5	1.5	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5	2.0	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.5	2.0	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.5	1.0	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.5	3.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5	2.5	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5	3.0	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.5	2.3	GO:0070980	biphenyl catabolic process(GO:0070980)
0.5	1.9	GO:0006601	creatine biosynthetic process(GO:0006601)
0.4	1.3	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.4	1.3	GO:0031630	regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4	1.7	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.4	2.9	GO:0050917	sensory perception of umami taste(GO:0050917)
0.4	0.8	GO:0021623	oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.4	1.2	GO:2000854	positive regulation of corticosterone secretion(GO:2000854)
0.4	1.2	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.4	6.9	GO:0015871	choline transport(GO:0015871)
0.4	2.0	GO:0002159	desmosome assembly(GO:0002159)
0.4	4.7	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.4	3.1	GO:0032439	endosome localization(GO:0032439)
0.4	2.7	GO:0002933	lipid hydroxylation(GO:0002933)
0.4	2.2	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4	1.1	GO:0016999	antibiotic metabolic process(GO:0016999)
0.4	2.9	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4	3.6	GO:0006526	arginine biosynthetic process(GO:0006526)
0.4	1.4	GO:0044691	tooth eruption(GO:0044691)
0.4	1.8	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.3	2.4	GO:0050915	sensory perception of sour taste(GO:0050915)
0.3	4.4	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3	3.7	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.3	1.0	GO:0021650	vestibulocochlear nerve formation(GO:0021650)
0.3	1.6	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.3	1.6	GO:0060023	soft palate development(GO:0060023)
0.3	5.8	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3	1.3	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.3	3.2	GO:1990504	dense core granule exocytosis(GO:1990504)
0.3	2.6	GO:0071104	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104)
0.3	0.6	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.3	0.9	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3	2.2	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.3	0.9	GO:1902490	regulation of sperm capacitation(GO:1902490)
0.3	1.2	GO:0042369	vitamin D catabolic process(GO:0042369)
0.3	1.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	0.9	GO:0008089	anterograde axonal transport(GO:0008089) axonal transport(GO:0098930)
0.3	4.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3	10.8	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.3	0.9	GO:0060596	mammary placode formation(GO:0060596)
0.3	0.9	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911)
0.3	0.9	GO:0038162	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) erythropoietin-mediated signaling pathway(GO:0038162)
0.3	0.6	GO:1904862	inhibitory synapse assembly(GO:1904862)
0.3	1.1	GO:0018352	protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.3	0.3	GO:0010157	response to chlorate(GO:0010157)
0.3	0.6	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
0.3	2.8	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.3	1.4	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173)
0.3	1.1	GO:0000706	meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.3	0.8	GO:0006624	vacuolar protein processing(GO:0006624)
0.3	1.1	GO:0060166	olfactory pit development(GO:0060166)
0.3	0.8	GO:1990426	homologous recombination-dependent replication fork processing(GO:1990426)
0.3	1.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.3	0.5	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3	0.8	GO:0001546	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3	2.6	GO:0009414	response to water deprivation(GO:0009414)
0.3	6.9	GO:0034063	stress granule assembly(GO:0034063)
0.3	5.8	GO:0016264	gap junction assembly(GO:0016264)
0.3	2.4	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
0.3	1.0	GO:0032849	positive regulation of cellular pH reduction(GO:0032849)
0.2	0.7	GO:0050894	determination of affect(GO:0050894)
0.2	3.7	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.2	1.5	GO:0042816	vitamin B6 metabolic process(GO:0042816)
0.2	1.5	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.2	0.7	GO:0015680	intracellular copper ion transport(GO:0015680)
0.2	4.1	GO:0014041	regulation of neuron maturation(GO:0014041)
0.2	1.7	GO:1902896	terminal web assembly(GO:1902896)
0.2	6.6	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.2	2.3	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2	1.6	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2	0.7	GO:0042489	negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.2	2.9	GO:0016554	cytidine to uridine editing(GO:0016554)
0.2	2.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.2	3.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.2	1.7	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2	2.6	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2	2.4	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.2	5.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.2	1.5	GO:1901660	calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.2	1.4	GO:0001705	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.2	2.9	GO:1902669	positive regulation of axon guidance(GO:1902669)
0.2	0.6	GO:0006742	NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2	3.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.2	2.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	0.6	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.2	2.1	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.2	1.5	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.2	4.7	GO:0098926	acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2	1.1	GO:0099540	synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2	1.3	GO:1903575	cornified envelope assembly(GO:1903575)
0.2	2.4	GO:1990035	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2	11.0	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2	2.2	GO:0016322	neuron remodeling(GO:0016322)
0.2	1.7	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.2	2.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	1.3	GO:0050955	thermoception(GO:0050955)
0.2	3.2	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2	0.9	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.2	0.5	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2	4.4	GO:0036158	outer dynein arm assembly(GO:0036158)
0.2	17.0	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.2	1.7	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.2	5.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2	1.2	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.2	2.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2	0.8	GO:0070494	regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2	0.5	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.2	1.8	GO:0060056	mammary gland involution(GO:0060056)
0.2	1.7	GO:0034201	response to oleic acid(GO:0034201)
0.2	1.1	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.2	1.8	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2	0.8	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.2	2.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.2	0.5	GO:0016062	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2	0.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.2	0.5	GO:1902303	regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2	0.2	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.2	8.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.2	2.6	GO:0031268	pseudopodium organization(GO:0031268)
0.2	0.8	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1	0.6	GO:0052026	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1	4.6	GO:0010842	retina layer formation(GO:0010842)
0.1	2.8	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	1.5	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.1	0.7	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	1.3	GO:0021842	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1	1.4	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	3.2	GO:0051639	actin filament network formation(GO:0051639)
0.1	3.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.1	0.7	GO:0043335	protein unfolding(GO:0043335)
0.1	5.3	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.1	1.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	1.0	GO:0060174	limb bud formation(GO:0060174)
0.1	4.2	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1	1.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	4.5	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.3	GO:2000018	regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020) negative regulation of female gonad development(GO:2000195)
0.1	2.6	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.5	GO:0034334	adherens junction maintenance(GO:0034334)
0.1	0.4	GO:0070295	renal water absorption(GO:0070295)
0.1	2.3	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.1	0.5	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.9	GO:1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1	17.8	GO:0070268	cornification(GO:0070268)
0.1	0.9	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	0.7	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	4.6	GO:0007340	acrosome reaction(GO:0007340)
0.1	0.5	GO:1900673	phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
0.1	0.7	GO:0030421	defecation(GO:0030421)
0.1	0.4	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1	0.6	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.6	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.1	3.5	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.1	3.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.1	0.3	GO:1990697	protein depalmitoleylation(GO:1990697)
0.1	0.5	GO:0014859	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1	0.9	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
0.1	1.5	GO:0046621	negative regulation of organ growth(GO:0046621)
0.1	7.5	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.1	2.7	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	4.1	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.1	0.7	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	1.1	GO:0018149	peptide cross-linking(GO:0018149)
0.1	0.3	GO:0006097	glyoxylate cycle(GO:0006097)
0.1	3.8	GO:0071625	vocalization behavior(GO:0071625)
0.1	1.0	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.1	0.2	GO:0001575	globoside metabolic process(GO:0001575)
0.1	0.8	GO:0072675	osteoclast fusion(GO:0072675)
0.1	0.5	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1	5.6	GO:0048599	oocyte development(GO:0048599)
0.1	0.8	GO:0034465	response to carbon monoxide(GO:0034465)
0.1	0.6	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.6	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.1	0.4	GO:0000294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.1	0.4	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
0.1	2.1	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.1	1.7	GO:0046415	urate metabolic process(GO:0046415)
0.1	1.6	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	1.5	GO:0033623	regulation of integrin activation(GO:0033623)
0.1	2.7	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	0.9	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.1	7.2	GO:0015701	bicarbonate transport(GO:0015701)
0.1	0.5	GO:0071500	cellular response to nitrosative stress(GO:0071500)
0.1	0.5	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	1.8	GO:0048266	behavioral response to pain(GO:0048266)
0.1	1.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	1.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1	1.6	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	2.6	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.4	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
0.1	1.0	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.1	0.5	GO:0015853	adenine transport(GO:0015853)
0.1	0.9	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	0.9	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.1	0.9	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.9	GO:1990822	basic amino acid transmembrane transport(GO:1990822)
0.1	2.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.1	0.2	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	0.7	GO:0030043	actin filament fragmentation(GO:0030043)
0.1	0.6	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.3	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1	1.3	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1	1.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	1.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.1	3.6	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	2.6	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	0.4	GO:0038169	somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1	3.3	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.1	0.7	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1	2.8	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	4.9	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	5.4	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.1	0.3	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.1	1.6	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1	0.5	GO:0010820	positive regulation of T cell chemotaxis(GO:0010820)
0.1	0.1	GO:0061300	cerebellum vasculature development(GO:0061300)
0.1	2.7	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.1	1.5	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.8	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.7	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	1.5	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1	1.4	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	1.5	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	2.2	GO:0003341	cilium movement(GO:0003341)
0.1	0.2	GO:1900369	transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.1	1.2	GO:0051601	exocyst localization(GO:0051601)
0.1	2.2	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.1	0.8	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.1	0.5	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.2	GO:0060406	positive regulation of penile erection(GO:0060406)
0.1	4.3	GO:0050909	sensory perception of taste(GO:0050909)
0.1	2.8	GO:0031102	neuron projection regeneration(GO:0031102)
0.1	0.2	GO:0034036	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1	0.5	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1	1.1	GO:0016540	protein autoprocessing(GO:0016540)
0.1	1.0	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.1	1.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.3	GO:0099624	atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1	0.2	GO:0042045	epithelial fluid transport(GO:0042045)
0.1	0.3	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.1	3.7	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.8	GO:0007162	negative regulation of cell adhesion(GO:0007162)
0.1	1.0	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.1	0.6	GO:0061436	regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1	0.2	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.1	0.4	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.1	0.3	GO:0033489	cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1	0.2	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1	0.4	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.1	1.2	GO:0003334	keratinocyte development(GO:0003334)
0.1	1.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.1	0.6	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1	0.7	GO:0035878	nail development(GO:0035878)
0.1	0.9	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.3	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.5	GO:0007631	feeding behavior(GO:0007631)
0.0	6.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	1.6	GO:0001709	cell fate determination(GO:0001709)
0.0	0.3	GO:0002158	osteoclast proliferation(GO:0002158)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.7	GO:0001967	suckling behavior(GO:0001967)
0.0	0.6	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.5	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.0	1.5	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.7	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.2	GO:0034343	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0	0.2	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.4	GO:0051121	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	1.2	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.4	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	1.0	GO:1900745	positive regulation of p38MAPK cascade(GO:1900745)
0.0	0.8	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.4	GO:0032484	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	1.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.9	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.4	GO:0010644	cell communication by electrical coupling(GO:0010644)
0.0	1.0	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.9	GO:0071786	endoplasmic reticulum tubular network organization(GO:0071786)
0.0	0.6	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.5	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.0	2.1	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.0	0.4	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.3	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.3	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.0	0.6	GO:0030238	male sex determination(GO:0030238)
0.0	0.8	GO:1903818	positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0	0.8	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.4	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	1.0	GO:0018210	peptidyl-threonine modification(GO:0018210)
0.0	0.2	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.4	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	2.3	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.9	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.3	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	1.9	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.0	0.3	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.0	0.9	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	1.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.3	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	4.4	GO:1900181	negative regulation of protein localization to nucleus(GO:1900181)
0.0	0.4	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.4	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.6	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.7	GO:0007179	transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0	1.0	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0	1.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.6	GO:0060009	Sertoli cell development(GO:0060009)
0.0	1.2	GO:0006312	mitotic recombination(GO:0006312)
0.0	0.7	GO:0014002	astrocyte development(GO:0014002)
0.0	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.2	GO:0048569	post-embryonic organ development(GO:0048569)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.9	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)
0.0	1.8	GO:0042446	hormone biosynthetic process(GO:0042446)
0.0	0.2	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.5	GO:0031529	ruffle organization(GO:0031529)
0.0	0.5	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.3	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0	0.3	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.5	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.5	GO:0060292	long term synaptic depression(GO:0060292)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	3.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	1.2	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.2	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.3	GO:0046580	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	1.6	GO:0042472	inner ear morphogenesis(GO:0042472)
0.0	1.5	GO:0090277	positive regulation of peptide hormone secretion(GO:0090277)
0.0	0.4	GO:0007224	smoothened signaling pathway(GO:0007224)
0.0	1.1	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.6	GO:0015671	oxygen transport(GO:0015671)
0.0	0.5	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.9	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.3	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0	0.3	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.0	0.1	GO:0001694	histamine biosynthetic process(GO:0001694)
0.0	0.8	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	2.6	GO:0046546	male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0	0.3	GO:0010975	regulation of neuron projection development(GO:0010975)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.4	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.9	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.4	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0061050	regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0	0.8	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.8	GO:1902930	regulation of alcohol biosynthetic process(GO:1902930)
0.0	0.5	GO:0016180	snRNA processing(GO:0016180)
0.0	0.5	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.1	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.3	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.3	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.8	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	1.1	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.6	GO:0006458	'de novo' protein folding(GO:0006458)
0.0	0.7	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	1.3	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.0	4.3	GO:0007608	sensory perception of smell(GO:0007608)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.4	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.2	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.3	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	1.8	GO:0006836	neurotransmitter transport(GO:0006836)
0.0	1.2	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.3	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	0.3	GO:0001649	osteoblast differentiation(GO:0001649)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	1.4	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.3	GO:0007141	male meiosis I(GO:0007141)
0.0	1.2	GO:0017156	calcium ion regulated exocytosis(GO:0017156)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.4	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) regulation of grooming behavior(GO:2000821)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0051321	meiotic cell cycle(GO:0051321)
0.0	0.3	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.6	GO:0006835	dicarboxylic acid transport(GO:0006835)
0.0	0.2	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.6	GO:0006865	amino acid transport(GO:0006865)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	2.4	GO:0031258	lamellipodium membrane(GO:0031258)
1.0	3.1	GO:0097453	mesaxon(GO:0097453) ensheathing process(GO:1990015)
1.0	5.7	GO:0034678	smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.8	4.9	GO:0005594	collagen type IX trimer(GO:0005594)
0.8	31.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.7	2.2	GO:0001534	radial spoke(GO:0001534)
0.7	2.0	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.7	4.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.7	2.7	GO:0030849	autosome(GO:0030849)
0.6	10.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.5	1.6	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.5	2.7	GO:0043260	laminin-11 complex(GO:0043260)
0.5	4.2	GO:0070695	FHF complex(GO:0070695)
0.5	1.9	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.5	1.5	GO:0000229	cytoplasmic chromosome(GO:0000229)
0.5	1.4	GO:0005584	collagen type I trimer(GO:0005584)
0.4	2.5	GO:0097513	myosin II filament(GO:0097513)
0.4	1.2	GO:0005588	collagen type V trimer(GO:0005588)
0.4	1.2	GO:0071821	FANCM-MHF complex(GO:0071821)
0.4	3.6	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.3	4.1	GO:0061689	tricellular tight junction(GO:0061689)
0.3	9.0	GO:0005922	connexon complex(GO:0005922)
0.3	4.6	GO:0016342	catenin complex(GO:0016342)
0.3	3.4	GO:0071953	elastic fiber(GO:0071953)
0.3	4.8	GO:0045179	apical cortex(GO:0045179)
0.3	12.2	GO:0030057	desmosome(GO:0030057)
0.3	5.8	GO:0005915	zonula adherens(GO:0005915)
0.3	2.5	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	1.3	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.3	8.5	GO:0031528	microvillus membrane(GO:0031528)
0.3	4.1	GO:0001520	outer dense fiber(GO:0001520)
0.2	3.7	GO:0032426	stereocilium tip(GO:0032426)
0.2	6.5	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.2	9.0	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	2.0	GO:0005587	collagen type IV trimer(GO:0005587)
0.2	0.2	GO:0044299	C-fiber(GO:0044299)
0.2	18.9	GO:0045095	keratin filament(GO:0045095)
0.2	8.8	GO:0002080	acrosomal membrane(GO:0002080)
0.2	40.8	GO:0070160	occluding junction(GO:0070160)
0.2	1.0	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2	1.5	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	1.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.2	0.8	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.2	1.1	GO:1990357	terminal web(GO:1990357)
0.2	0.5	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	1.3	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2	15.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2	2.4	GO:0005883	neurofilament(GO:0005883)
0.2	1.5	GO:0005955	calcineurin complex(GO:0005955)
0.2	1.4	GO:0005683	U7 snRNP(GO:0005683)
0.2	0.6	GO:0016939	plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.1	4.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	1.7	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	1.4	GO:0071546	pi-body(GO:0071546)
0.1	20.2	GO:0005604	basement membrane(GO:0005604)
0.1	3.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	4.3	GO:0034451	centriolar satellite(GO:0034451)
0.1	3.4	GO:0031143	pseudopodium(GO:0031143)
0.1	3.2	GO:0034706	sodium channel complex(GO:0034706)
0.1	3.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	2.3	GO:0043194	axon initial segment(GO:0043194)
0.1	2.8	GO:0031045	dense core granule(GO:0031045)
0.1	0.4	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	1.1	GO:0044327	dendritic spine head(GO:0044327)
0.1	1.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	2.0	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.6	GO:0002177	manchette(GO:0002177)
0.1	4.4	GO:0031941	filamentous actin(GO:0031941)
0.1	2.2	GO:0044453	nuclear membrane part(GO:0044453)
0.1	1.9	GO:0000800	lateral element(GO:0000800)
0.1	0.5	GO:0098536	deuterosome(GO:0098536)
0.1	8.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	16.4	GO:0031225	anchored component of membrane(GO:0031225)
0.1	1.3	GO:0032433	filopodium tip(GO:0032433)
0.1	0.4	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	5.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	16.1	GO:0030658	transport vesicle membrane(GO:0030658)
0.1	7.6	GO:0060170	ciliary membrane(GO:0060170)
0.1	0.2	GO:0031379	RNA-directed RNA polymerase complex(GO:0031379)
0.1	2.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.4	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	3.9	GO:0097542	ciliary tip(GO:0097542)
0.1	2.6	GO:0031201	SNARE complex(GO:0031201)
0.1	0.4	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	4.6	GO:0031526	brush border membrane(GO:0031526)
0.1	4.8	GO:0043195	terminal bouton(GO:0043195)
0.1	0.5	GO:0098845	postsynaptic endosome(GO:0098845)
0.1	4.3	GO:0005882	intermediate filament(GO:0005882)
0.1	0.6	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.0	0.5	GO:0097227	sperm annulus(GO:0097227)
0.0	17.8	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.6	GO:0097433	dense body(GO:0097433)
0.0	11.3	GO:0005795	Golgi stack(GO:0005795)
0.0	6.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.8	GO:0031209	SCAR complex(GO:0031209)
0.0	3.6	GO:0000786	nucleosome(GO:0000786)
0.0	4.5	GO:0034707	chloride channel complex(GO:0034707)
0.0	2.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.4	GO:0005902	microvillus(GO:0005902)
0.0	0.3	GO:0071817	MMXD complex(GO:0071817)
0.0	1.0	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.0	1.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	2.7	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.8	GO:0042627	chylomicron(GO:0042627)
0.0	15.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.6	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.9	GO:0000145	exocyst(GO:0000145)
0.0	0.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.5	GO:0030478	actin cap(GO:0030478)
0.0	0.5	GO:0032039	integrator complex(GO:0032039)
0.0	1.0	GO:0032420	stereocilium(GO:0032420)
0.0	1.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.3	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.7	GO:0000242	pericentriolar material(GO:0000242)
0.0	1.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	2.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.6	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	2.4	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.7	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.9	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.8	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.8	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	1.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.5	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	2.8	GO:0005884	actin filament(GO:0005884)
0.0	2.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	1.7	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	1.2	GO:0030133	transport vesicle(GO:0030133)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.7	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.9	GO:0005581	collagen trimer(GO:0005581)
0.0	0.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	4.2	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.5	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	2.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.7	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.9	GO:0005871	kinesin complex(GO:0005871)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	11.5	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.3	3.9	GO:0005171	hepatocyte growth factor receptor binding(GO:0005171)
1.0	4.0	GO:0005260	channel-conductance-controlling ATPase activity(GO:0005260)
1.0	1.0	GO:0019210	kinase inhibitor activity(GO:0019210)
1.0	3.9	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.8	6.8	GO:0042289	MHC class II protein binding(GO:0042289)
0.8	2.5	GO:0008892	guanine deaminase activity(GO:0008892)
0.8	10.2	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.8	2.3	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.8	6.9	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.7	9.6	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.7	2.8	GO:0061714	folic acid receptor activity(GO:0061714)
0.7	4.7	GO:1990254	keratin filament binding(GO:1990254)
0.6	2.6	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.6	6.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.6	1.9	GO:0015067	amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.6	1.7	GO:0047225	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.5	3.1	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.5	1.5	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.5	10.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.5	20.2	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.5	1.4	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4	1.8	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.4	3.1	GO:0050294	steroid sulfotransferase activity(GO:0050294)
0.4	1.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4	6.9	GO:0005113	patched binding(GO:0005113)
0.4	9.0	GO:0005243	gap junction channel activity(GO:0005243)
0.4	1.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.4	2.5	GO:0044736	acid-sensing ion channel activity(GO:0044736)
0.4	12.9	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.4	2.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	4.4	GO:0034235	GPI anchor binding(GO:0034235)
0.4	3.1	GO:0019215	intermediate filament binding(GO:0019215)
0.4	10.0	GO:0019841	retinol binding(GO:0019841)
0.4	1.5	GO:0005042	netrin receptor activity(GO:0005042)
0.4	11.8	GO:0005003	ephrin receptor activity(GO:0005003)
0.4	1.5	GO:0008431	vitamin E binding(GO:0008431)
0.4	2.9	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.4	2.9	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.4	1.4	GO:0004040	amidase activity(GO:0004040)
0.4	5.3	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.4	3.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.3	1.7	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.3	1.4	GO:0071209	U7 snRNA binding(GO:0071209)
0.3	9.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.3	4.4	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3	1.0	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3	1.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3	4.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.3	2.5	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.3	2.5	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor beta-receptor activity(GO:0005019)
0.3	7.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	1.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.3	2.7	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.3	1.2	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3	1.5	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3	2.5	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.3	1.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3	1.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.3	2.5	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3	1.0	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2	1.2	GO:0004419	hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2	0.9	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2	1.5	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2	1.7	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	1.7	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2	4.8	GO:0051011	microtubule minus-end binding(GO:0051011)
0.2	3.9	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.2	1.5	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	2.1	GO:0001849	complement component C1q binding(GO:0001849)
0.2	5.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.2	1.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	5.8	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.2	3.2	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	0.9	GO:0004461	lactose synthase activity(GO:0004461)
0.2	3.3	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	2.6	GO:0050693	LBD domain binding(GO:0050693)
0.2	0.5	GO:0004794	L-threonine ammonia-lyase activity(GO:0004794)
0.2	0.8	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2	3.0	GO:0015250	water channel activity(GO:0015250)
0.2	0.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	1.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.2	2.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	2.2	GO:0008430	selenium binding(GO:0008430)
0.2	2.6	GO:0033691	sialic acid binding(GO:0033691)
0.2	6.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	3.7	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	2.7	GO:0070513	death domain binding(GO:0070513)
0.1	3.5	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	1.0	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	1.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	1.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	2.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	4.8	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	0.5	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.7	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	3.0	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	3.0	GO:0000146	microfilament motor activity(GO:0000146)
0.1	0.5	GO:0015207	ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.1	12.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	18.1	GO:0030276	clathrin binding(GO:0030276)
0.1	3.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	2.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	3.4	GO:0008527	taste receptor activity(GO:0008527)
0.1	1.3	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.3	GO:1990699	palmitoleyl hydrolase activity(GO:1990699)
0.1	1.7	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	0.3	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1	1.7	GO:0070700	BMP receptor binding(GO:0070700)
0.1	1.0	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	1.7	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	1.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.3	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1	0.8	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	3.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	1.1	GO:0005497	androgen binding(GO:0005497)
0.1	2.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	16.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	1.4	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.1	3.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	1.2	GO:1901611	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1	2.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.5	GO:0002046	opsin binding(GO:0002046)
0.1	4.9	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.8	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	0.4	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.1	1.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	1.0	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.9	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	1.2	GO:0089720	caspase binding(GO:0089720)
0.1	0.7	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	1.0	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.7	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.2	GO:0033149	FFAT motif binding(GO:0033149)
0.1	2.6	GO:0031489	myosin V binding(GO:0031489)
0.1	7.5	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	1.3	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.4	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	1.8	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.1	1.3	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	0.5	GO:0016402	pristanoyl-CoA oxidase activity(GO:0016402)
0.1	0.3	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1	2.3	GO:0031005	filamin binding(GO:0031005)
0.1	0.7	GO:1903136	cuprous ion binding(GO:1903136)
0.1	0.4	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	3.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.7	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	1.7	GO:0043274	phospholipase binding(GO:0043274)
0.1	3.2	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	1.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	1.5	GO:0048185	activin binding(GO:0048185)
0.1	0.5	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.1	0.6	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	1.1	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1	0.6	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1	2.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.6	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.8	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	0.2	GO:0003968	RNA-directed RNA polymerase activity(GO:0003968)
0.1	6.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	1.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1	1.3	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.6	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.7	GO:0038132	neuregulin binding(GO:0038132)
0.1	0.4	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	0.5	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	1.1	GO:0042805	actinin binding(GO:0042805)
0.1	0.8	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1	0.9	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	1.2	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	2.3	GO:0005158	insulin receptor binding(GO:0005158)
0.1	0.4	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1	0.9	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.3	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	0.3	GO:0008422	beta-glucosidase activity(GO:0008422)
0.1	0.5	GO:0000155	phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.1	0.2	GO:0052642	lysophosphatidic acid phosphatase activity(GO:0052642)
0.1	0.6	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.9	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.3	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.1	GO:0017082	mineralocorticoid receptor activity(GO:0017082)
0.0	1.4	GO:0005504	fatty acid binding(GO:0005504)
0.0	1.9	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	1.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.3	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0	0.5	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	3.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.5	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	1.4	GO:0005326	neurotransmitter transporter activity(GO:0005326)
0.0	0.2	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	1.5	GO:0008483	transaminase activity(GO:0008483)
0.0	2.3	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.0	0.2	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	7.7	GO:0005178	integrin binding(GO:0005178)
0.0	0.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.3	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.5	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.3	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	1.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.6	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.3	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	1.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	1.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	6.3	GO:0000149	SNARE binding(GO:0000149)
0.0	0.5	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	1.9	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.6	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.2	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	1.6	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.4	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.6	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.6	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.9	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	1.7	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	1.1	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.9	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.7	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.3	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	1.0	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	1.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.6	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	1.9	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.1	GO:0005046	KDEL sequence binding(GO:0005046)
0.0	2.4	GO:0016879	ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0	0.5	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	6.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.7	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.5	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.5	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.5	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	1.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.7	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	3.1	GO:0005506	iron ion binding(GO:0005506)
0.0	19.1	GO:0005198	structural molecule activity(GO:0005198)
0.0	1.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0010858	calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	1.7	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	1.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.4	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	1.0	GO:0002020	protease binding(GO:0002020)
0.0	1.3	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	1.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.3	GO:0015464	acetylcholine receptor activity(GO:0015464)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	16.2	NABA COLLAGENS	Genes encoding collagen proteins
0.2	11.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	12.5	PID EPHA FWDPATHWAY	EPHA forward signaling
0.2	1.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.2	7.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	6.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	4.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	8.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	6.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	2.9	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	5.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	5.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	2.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	9.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	3.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	1.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	18.1	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	1.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	3.0	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	1.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	2.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	2.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	2.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	3.3	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	2.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	1.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.0	PID FGF PATHWAY	FGF signaling pathway
0.0	0.8	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.2	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	40.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.7	10.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5	12.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3	9.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	8.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.3	5.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	3.9	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	10.7	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	0.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	3.0	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.2	4.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	15.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	6.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	4.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	2.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	6.0	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	3.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	2.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	6.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	6.4	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	2.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.8	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	10.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.1	6.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	1.9	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1	2.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	2.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	8.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	1.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	3.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	2.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	3.9	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	1.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.5	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	4.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	6.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	13.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	1.9	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.6	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	6.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	6.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.7	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	1.0	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	2.4	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.7	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	2.0	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.4	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.0	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	1.9	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.6	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME SHC MEDIATED CASCADE	Genes involved in SHC-mediated cascade
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	3.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation

Results for TWIST1_SNAI1

Z-value: 0.93

Motif logo

Transcription factors associated with TWIST1_SNAI1

Activity-expression correlation:

Activity profile of TWIST1_SNAI1 motif

Sorted Z-values of TWIST1_SNAI1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TWIST1_SNAI1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: