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Illumina Body Map 2, young vs old

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Results for UAUUGCU

Z-value: 0.64

Motif logo

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miRNA associated with seed UAUUGCU

NamemiRBASE accession
hsa-miR-137
MIMAT0000429

Activity profile of UAUUGCU motif

Sorted Z-values of UAUUGCU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_236849754 5.33 ENST00000542672.1
ENST00000366578.4
ACTN2
actinin, alpha 2
chr1_-_33338076 3.59 ENST00000496770.1
FNDC5
fibronectin type III domain containing 5
chr13_+_23755054 3.17 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr19_-_2721412 2.97 ENST00000323469.4
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr15_+_85359911 2.72 ENST00000258888.5
ALPK3
alpha-kinase 3
chr12_+_125811162 2.64 ENST00000299308.3
TMEM132B
transmembrane protein 132B
chr11_+_109292846 2.55 ENST00000327419.6
C11orf87
chromosome 11 open reading frame 87
chr1_+_237205476 2.50 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr1_-_217262969 2.39 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr6_+_17281573 2.39 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr8_-_124553437 2.39 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr19_-_11591848 2.32 ENST00000359227.3
ELAVL3
ELAV like neuron-specific RNA binding protein 3
chr11_-_18765389 2.23 ENST00000477854.1
PTPN5
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr17_-_37764128 2.23 ENST00000302584.4
NEUROD2
neuronal differentiation 2
chr1_-_119532127 2.20 ENST00000207157.3
TBX15
T-box 15
chr8_-_22014339 2.18 ENST00000306317.2
LGI3
leucine-rich repeat LGI family, member 3
chr2_-_50574856 2.17 ENST00000342183.5
NRXN1
neurexin 1
chr5_+_7396141 2.15 ENST00000338316.4
ADCY2
adenylate cyclase 2 (brain)
chr2_-_213403565 2.15 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr11_-_47374246 2.14 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr9_-_101471479 2.10 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr13_-_25746416 2.10 ENST00000515384.1
ENST00000357816.2
AMER2
APC membrane recruitment protein 2
chr1_+_95582881 2.10 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr2_+_207308220 2.03 ENST00000264377.3
ADAM23
ADAM metallopeptidase domain 23
chr10_+_115803650 1.94 ENST00000369295.2
ADRB1
adrenoceptor beta 1
chr3_+_11034403 1.92 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr9_-_93405352 1.88 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr3_+_85008089 1.85 ENST00000383699.3
CADM2
cell adhesion molecule 2
chr11_-_61348576 1.83 ENST00000263846.4
SYT7
synaptotagmin VII
chr5_+_161274685 1.83 ENST00000428797.2
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_152870106 1.71 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr18_-_70535177 1.69 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr10_+_25463951 1.66 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr19_+_589893 1.66 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr5_+_79331164 1.66 ENST00000350881.2
THBS4
thrombospondin 4
chr1_-_31712401 1.63 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr6_-_46293378 1.61 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chrX_+_152953505 1.61 ENST00000253122.5
SLC6A8
solute carrier family 6 (neurotransmitter transporter), member 8
chr4_-_141348999 1.58 ENST00000325617.5
CLGN
calmegin
chr20_-_48099182 1.58 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr11_+_22359562 1.57 ENST00000263160.3
SLC17A6
solute carrier family 17 (vesicular glutamate transporter), member 6
chr12_+_5019061 1.57 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr6_-_90121938 1.56 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr20_+_24449821 1.56 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr4_-_53525406 1.55 ENST00000451218.2
ENST00000441222.3
USP46
ubiquitin specific peptidase 46
chr2_-_166930131 1.54 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr20_-_656823 1.53 ENST00000246104.6
SCRT2
scratch family zinc finger 2
chr14_+_72399833 1.51 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr6_-_166796461 1.51 ENST00000360961.6
ENST00000341756.6
MPC1
mitochondrial pyruvate carrier 1
chr10_-_69455873 1.50 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr9_-_19786926 1.48 ENST00000341998.2
ENST00000286344.3
SLC24A2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr1_-_211307315 1.47 ENST00000271751.4
KCNH1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr1_+_110693103 1.46 ENST00000331565.4
SLC6A17
solute carrier family 6 (neutral amino acid transporter), member 17
chr8_-_40755333 1.46 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr3_+_49591881 1.45 ENST00000296452.4
BSN
bassoon presynaptic cytomatrix protein
chr8_+_142402089 1.45 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3
protein tyrosine phosphatase type IVA, member 3
chr14_-_35182994 1.42 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr2_-_158485387 1.39 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr19_+_35521572 1.36 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr14_+_65171099 1.36 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_40679186 1.34 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_-_153457197 1.34 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr7_+_136553370 1.34 ENST00000445907.2
CHRM2
cholinergic receptor, muscarinic 2
chr22_-_33454354 1.32 ENST00000358763.2
SYN3
synapsin III
chr20_-_32262165 1.31 ENST00000606690.1
ENST00000246190.6
ENST00000439478.1
ENST00000375238.4
NECAB3
N-terminal EF-hand calcium binding protein 3
chr11_+_24518723 1.31 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr15_-_65809581 1.30 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr19_+_10527449 1.30 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr3_-_186080012 1.30 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr2_+_155554797 1.30 ENST00000295101.2
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr6_-_11044509 1.29 ENST00000354666.3
ELOVL2
ELOVL fatty acid elongase 2
chr5_-_83680603 1.29 ENST00000296591.5
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr17_+_56833184 1.28 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr1_-_47134101 1.26 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr11_+_119019722 1.26 ENST00000307417.3
ABCG4
ATP-binding cassette, sub-family G (WHITE), member 4
chr12_-_85306594 1.22 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr3_+_42695176 1.22 ENST00000232974.6
ENST00000457842.3
ZBTB47
zinc finger and BTB domain containing 47
chr20_-_60982330 1.21 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr2_-_37193606 1.20 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr11_-_1593150 1.20 ENST00000397374.3
DUSP8
dual specificity phosphatase 8
chr3_+_20081515 1.20 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr2_+_157291953 1.19 ENST00000310454.6
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr11_-_45687128 1.19 ENST00000308064.2
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr3_-_33686743 1.17 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr15_+_90544532 1.17 ENST00000268154.4
ZNF710
zinc finger protein 710
chr9_-_134145880 1.17 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr6_+_117586713 1.13 ENST00000352536.3
ENST00000326274.5
VGLL2
vestigial like 2 (Drosophila)
chr1_-_146644122 1.13 ENST00000254101.3
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr9_-_34523027 1.12 ENST00000399775.2
ENHO
energy homeostasis associated
chr1_-_111150048 1.12 ENST00000485317.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr11_-_790060 1.12 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr9_-_111929560 1.11 ENST00000561981.2
FRRS1L
ferric-chelate reductase 1-like
chr7_-_44530479 1.10 ENST00000355451.7
NUDCD3
NudC domain containing 3
chr14_+_53019822 1.10 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr14_+_93897199 1.10 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr9_-_91793675 1.10 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr9_+_34990219 1.09 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr1_-_67266939 1.09 ENST00000304526.2
INSL5
insulin-like 5
chr5_+_10564432 1.09 ENST00000296657.5
ANKRD33B
ankyrin repeat domain 33B
chr7_+_28452130 1.08 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr1_-_232697304 1.08 ENST00000366630.1
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr11_-_88796803 1.07 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr20_-_42939782 1.07 ENST00000396825.3
FITM2
fat storage-inducing transmembrane protein 2
chr5_-_107717058 1.07 ENST00000359660.5
FBXL17
F-box and leucine-rich repeat protein 17
chr1_-_193155729 1.05 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_24536253 1.05 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr11_+_64073699 1.05 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr7_-_74867509 1.04 ENST00000426327.3
GATSL2
GATS protein-like 2
chr8_-_145559943 1.04 ENST00000332135.4
SCRT1
scratch family zinc finger 1
chr8_-_53322303 1.03 ENST00000276480.7
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr16_+_68279207 1.03 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
PLA2G15
phospholipase A2, group XV
chr19_-_17445613 1.02 ENST00000159087.4
ANO8
anoctamin 8
chr10_+_125425871 1.02 ENST00000284674.1
GPR26
G protein-coupled receptor 26
chr19_+_13135386 1.01 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_41131326 1.00 ENST00000372684.3
RIMS3
regulating synaptic membrane exocytosis 3
chr2_+_173940442 1.00 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr8_-_139509065 1.00 ENST00000395297.1
FAM135B
family with sequence similarity 135, member B
chr1_+_231664390 0.99 ENST00000366639.4
ENST00000413309.2
TSNAX
translin-associated factor X
chr14_+_93389425 0.99 ENST00000216492.5
ENST00000334654.4
CHGA
chromogranin A (parathyroid secretory protein 1)
chr7_-_122526799 0.98 ENST00000334010.7
ENST00000313070.7
CADPS2
Ca++-dependent secretion activator 2
chr19_-_409134 0.98 ENST00000332235.6
C2CD4C
C2 calcium-dependent domain containing 4C
chr2_+_162272605 0.98 ENST00000389554.3
TBR1
T-box, brain, 1
chr17_-_74236382 0.98 ENST00000592271.1
ENST00000319945.6
ENST00000269391.6
RNF157
ring finger protein 157
chr8_+_107670064 0.97 ENST00000312046.6
OXR1
oxidation resistance 1
chr8_-_114389353 0.96 ENST00000343508.3
CSMD3
CUB and Sushi multiple domains 3
chr20_-_42816206 0.94 ENST00000372980.3
JPH2
junctophilin 2
chr4_+_150999418 0.94 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr11_-_132813566 0.93 ENST00000331898.7
OPCML
opioid binding protein/cell adhesion molecule-like
chr16_+_28303804 0.93 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr1_-_46598284 0.93 ENST00000423209.1
ENST00000262741.5
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr9_-_130890662 0.91 ENST00000277462.5
ENST00000338961.6
PTGES2
prostaglandin E synthase 2
chr20_+_8112824 0.90 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr12_-_111021110 0.90 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr5_-_131132614 0.89 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr1_+_42846443 0.89 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr12_+_109490370 0.88 ENST00000257548.5
ENST00000536723.1
ENST00000536393.1
USP30
ubiquitin specific peptidase 30
chr4_+_41362796 0.88 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr3_-_9291063 0.88 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr19_+_47104493 0.87 ENST00000291295.9
ENST00000597743.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr1_+_220701456 0.85 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr7_+_97736197 0.85 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr1_-_72748417 0.84 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chrX_+_113818545 0.84 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr16_+_11762270 0.84 ENST00000329565.5
SNN
stannin
chr14_+_79745746 0.84 ENST00000281127.7
NRXN3
neurexin 3
chr1_-_149982624 0.84 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr21_+_45285050 0.84 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr6_-_55443975 0.83 ENST00000308161.4
ENST00000398661.2
ENST00000274901.4
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr6_+_69345166 0.83 ENST00000370598.1
BAI3
brain-specific angiogenesis inhibitor 3
chr10_-_735553 0.82 ENST00000280886.6
ENST00000423550.1
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr4_-_122854612 0.82 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr13_-_110438914 0.82 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr18_-_30050395 0.81 ENST00000269209.6
ENST00000399218.4
GAREM
GRB2 associated, regulator of MAPK1
chr5_-_57756087 0.80 ENST00000274289.3
PLK2
polo-like kinase 2
chr2_-_180726232 0.79 ENST00000410066.1
ZNF385B
zinc finger protein 385B
chr20_-_43438912 0.78 ENST00000541604.2
ENST00000372851.3
RIMS4
regulating synaptic membrane exocytosis 4
chr4_-_142053952 0.78 ENST00000515673.2
RNF150
ring finger protein 150
chr5_-_133968529 0.78 ENST00000402673.2
SAR1B
SAR1 homolog B (S. cerevisiae)
chr22_+_50781723 0.77 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
PPP6R2
protein phosphatase 6, regulatory subunit 2
chr11_+_12695944 0.77 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_-_126076264 0.76 ENST00000296233.3
KLF15
Kruppel-like factor 15
chrX_+_28605516 0.75 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_-_197457335 0.75 ENST00000260983.3
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_-_117667806 0.75 ENST00000527706.1
ENST00000321322.6
DSCAML1
Down syndrome cell adhesion molecule like 1
chr20_+_44657845 0.74 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr20_-_5931109 0.73 ENST00000203001.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr20_-_55841662 0.72 ENST00000395863.3
ENST00000450594.2
BMP7
bone morphogenetic protein 7
chr4_+_93225550 0.72 ENST00000282020.4
GRID2
glutamate receptor, ionotropic, delta 2
chr5_-_59189545 0.72 ENST00000340635.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_51985001 0.71 ENST00000354534.6
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr4_+_144106080 0.71 ENST00000307017.4
USP38
ubiquitin specific peptidase 38
chr15_-_55881135 0.71 ENST00000302000.6
PYGO1
pygopus family PHD finger 1
chr8_-_92053212 0.71 ENST00000285419.3
TMEM55A
transmembrane protein 55A
chr14_+_102829300 0.71 ENST00000359520.7
TECPR2
tectonin beta-propeller repeat containing 2
chr17_+_11924129 0.70 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr8_-_105601134 0.70 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr22_+_29876197 0.70 ENST00000310624.6
NEFH
neurofilament, heavy polypeptide
chr9_-_14693417 0.69 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr8_-_103251274 0.69 ENST00000251810.3
RRM2B
ribonucleotide reductase M2 B (TP53 inducible)
chr6_+_96463840 0.69 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr9_-_28670283 0.69 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr10_-_102989551 0.69 ENST00000370193.2
LBX1
ladybird homeobox 1
chr5_+_127419449 0.69 ENST00000262461.2
ENST00000343225.4
SLC12A2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr2_+_86947296 0.68 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr12_-_31744031 0.68 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr1_+_214161272 0.67 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr7_-_117513540 0.67 ENST00000160373.3
CTTNBP2
cortactin binding protein 2
chr1_-_153919128 0.67 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chr15_+_33603147 0.65 ENST00000415757.3
ENST00000389232.4
RYR3
ryanodine receptor 3
chr2_+_198380289 0.65 ENST00000233892.4
ENST00000409916.1
MOB4
MOB family member 4, phocein
chr3_-_119813264 0.64 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr16_-_2264779 0.63 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr7_+_110731062 0.63 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr5_-_38595498 0.63 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr12_+_79258547 0.62 ENST00000457153.2
SYT1
synaptotagmin I
chr12_-_10875831 0.62 ENST00000279550.7
ENST00000228251.4
YBX3
Y box binding protein 3
chr13_-_21476900 0.62 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr4_+_26585538 0.62 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr2_-_33824336 0.61 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A
family with sequence similarity 98, member A
chr5_+_63802109 0.61 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of UAUUGCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.8 2.5 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.7 2.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.6 1.9 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.5 1.6 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.5 1.9 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.5 1.4 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.5 1.8 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 2.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 1.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.4 1.6 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.4 1.5 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.4 0.7 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.3 1.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.3 1.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.0 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.3 2.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.3 0.9 GO:0090427 activation of meiosis(GO:0090427)
0.3 1.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 0.9 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.3 2.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 4.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 2.7 GO:0015820 leucine transport(GO:0015820)
0.3 1.3 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 1.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.3 1.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.7 GO:0040040 thermosensory behavior(GO:0040040)
0.2 2.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 1.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.2 1.7 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 0.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.3 GO:0021764 amygdala development(GO:0021764)
0.2 0.7 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.2 0.9 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 1.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.9 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2 0.6 GO:0071109 superior temporal gyrus development(GO:0071109)
0.2 0.8 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.2 1.0 GO:0008050 female courtship behavior(GO:0008050)
0.2 0.6 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.2 2.5 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 1.0 GO:0016240 autophagosome docking(GO:0016240)
0.2 1.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 1.6 GO:0071233 cellular response to leucine(GO:0071233)
0.2 0.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 1.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 2.0 GO:0071321 cellular response to cGMP(GO:0071321)
0.2 0.5 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 1.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.2 1.1 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.2 0.6 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 1.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.5 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 1.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.4 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 2.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 2.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.4 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 1.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 1.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.8 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 1.0 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 1.3 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.9 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.7 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 1.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 2.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0001570 vasculogenesis(GO:0001570)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.4 GO:0019236 response to pheromone(GO:0019236)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.9 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.5 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 1.3 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.7 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 1.1 GO:1902001 carnitine shuttle(GO:0006853) fatty acid transmembrane transport(GO:1902001)
0.0 1.7 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.0 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.8 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 1.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.8 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.6 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0060074 synapse maturation(GO:0060074)
0.0 1.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 1.0 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.4 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0086010 neuronal action potential(GO:0019228) membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 1.1 GO:0007398 ectoderm development(GO:0007398)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0048864 stem cell development(GO:0048864)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 1.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.8 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.7 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.0 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.4 GO:0035418 protein localization to synapse(GO:0035418)
0.0 1.3 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0033572 transferrin transport(GO:0033572)
0.0 0.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.6 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.3 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 1.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 2.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 1.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0098855 HCN channel complex(GO:0098855)
0.5 2.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.5 2.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 2.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.3 3.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.5 GO:0032279 asymmetric synapse(GO:0032279)
0.3 1.7 GO:0044308 axonal spine(GO:0044308)
0.3 1.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0034657 GID complex(GO:0034657)
0.2 1.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 3.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 4.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.8 GO:0032009 early phagosome(GO:0032009)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 4.9 GO:0031143 pseudopodium(GO:0031143)
0.1 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.5 GO:0043291 RAVE complex(GO:0043291)
0.1 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 1.2 GO:0000125 PCAF complex(GO:0000125)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 1.9 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.3 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 1.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.7 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 2.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 3.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 5.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 1.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:1990909 Wnt signalosome(GO:1990909)
0.0 3.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 4.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 4.4 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 2.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0070160 occluding junction(GO:0070160)
0.0 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.8 3.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.6 1.9 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.5 1.6 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.5 1.4 GO:0038100 nodal binding(GO:0038100)
0.4 1.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 2.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 1.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.4 1.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.4 3.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 1.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.3 1.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 2.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 1.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 1.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 1.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 0.8 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.2 1.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 1.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 1.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 5.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.2 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 1.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 0.8 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.2 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 1.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 2.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 1.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.7 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.3 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.7 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.7 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 4.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 2.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.5 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.6 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 3.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 4.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 2.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 1.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 3.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 4.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 1.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.5 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 2.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.0 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.2 PID IGF1 PATHWAY IGF1 pathway
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 2.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 4.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 5.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 5.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 3.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 2.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events