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Illumina Body Map 2, young vs old

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Results for UGACCUA

Z-value: 0.28

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miRNA associated with seed UGACCUA

NamemiRBASE accession
hsa-miR-192-5p
MIMAT0000222
hsa-miR-215-5p
MIMAT0000272

Activity profile of UGACCUA motif

Sorted Z-values of UGACCUA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_107110488 0.26 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr2_+_182850551 0.20 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr9_+_12693336 0.19 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr19_+_30863271 0.19 ENST00000355537.3
ZNF536
zinc finger protein 536
chr2_-_166930131 0.18 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_-_31845914 0.13 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr5_-_73937244 0.13 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1
ectodermal-neural cortex 1 (with BTB domain)
chr5_+_6448736 0.13 ENST00000399816.3
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr5_+_173315283 0.12 ENST00000265085.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_9970227 0.11 ENST00000377263.1
CTNNBIP1
catenin, beta interacting protein 1
chr3_-_9291063 0.11 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr17_+_38024417 0.10 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2
zona pellucida binding protein 2
chr12_+_52203789 0.10 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr7_+_28452130 0.09 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr5_+_95187934 0.09 ENST00000357880.3
ENST00000436592.1
C5orf27
chromosome 5 open reading frame 27
chr3_-_114790179 0.09 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr20_-_41818373 0.09 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr12_-_14133053 0.08 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr17_+_2699697 0.08 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr6_+_123317116 0.08 ENST00000275162.5
CLVS2
clavesin 2
chr6_+_39016551 0.07 ENST00000373256.4
GLP1R
glucagon-like peptide 1 receptor
chr1_+_10271674 0.07 ENST00000377086.1
KIF1B
kinesin family member 1B
chr3_-_42846021 0.07 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr18_+_49866496 0.07 ENST00000442544.2
DCC
deleted in colorectal carcinoma
chr2_+_115199876 0.07 ENST00000436732.1
ENST00000410059.1
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr4_+_172734548 0.07 ENST00000506823.1
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_+_184020398 0.06 ENST00000403733.3
ENST00000378925.3
WWC2
WW and C2 domain containing 2
chr6_+_117198400 0.06 ENST00000332958.2
RFX6
regulatory factor X, 6
chr1_+_84543734 0.06 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr22_-_22221900 0.06 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr17_+_27717415 0.06 ENST00000583121.1
ENST00000261716.3
TAOK1
TAO kinase 1
chrX_-_24045303 0.06 ENST00000328046.8
KLHL15
kelch-like family member 15
chr11_+_35684288 0.06 ENST00000299413.5
TRIM44
tripartite motif containing 44
chr17_-_33448468 0.06 ENST00000591723.1
ENST00000593039.1
ENST00000587405.1
RAD51L3-RFFL
RAD51D
Uncharacterized protein
RAD51 paralog D
chr5_-_39074479 0.06 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RICTOR
RPTOR independent companion of MTOR, complex 2
chr7_+_97736197 0.05 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr13_-_21476900 0.05 ENST00000400602.2
ENST00000255305.6
XPO4
exportin 4
chr14_+_57735614 0.05 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr3_+_38495333 0.05 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr17_-_33416231 0.05 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chrX_+_130192318 0.05 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr18_+_54318616 0.04 ENST00000254442.3
WDR7
WD repeat domain 7
chr17_-_56595196 0.04 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
MTMR4
myotubularin related protein 4
chr1_+_233749739 0.04 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr6_-_116381918 0.04 ENST00000606080.1
FRK
fyn-related kinase
chr8_+_61591337 0.04 ENST00000423902.2
CHD7
chromodomain helicase DNA binding protein 7
chr2_-_235405679 0.04 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr20_-_36156125 0.04 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr21_-_39288743 0.03 ENST00000609713.1
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_+_105085734 0.03 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr15_+_89631381 0.03 ENST00000352732.5
ABHD2
abhydrolase domain containing 2
chr12_+_108525517 0.03 ENST00000332082.4
WSCD2
WSC domain containing 2
chr1_+_181057638 0.03 ENST00000367577.4
IER5
immediate early response 5
chr12_+_862089 0.03 ENST00000315939.6
ENST00000537687.1
ENST00000447667.2
WNK1
WNK lysine deficient protein kinase 1
chr9_-_127533519 0.03 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr13_+_58206655 0.03 ENST00000377918.3
PCDH17
protocadherin 17
chr15_-_65670360 0.03 ENST00000327987.4
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr6_+_167412665 0.02 ENST00000366847.4
FGFR1OP
FGFR1 oncogene partner
chr12_+_56137064 0.02 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr1_+_67218124 0.02 ENST00000282670.2
TCTEX1D1
Tctex1 domain containing 1
chr16_+_69599861 0.02 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chrX_+_119737806 0.02 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chrX_-_63425561 0.02 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr1_-_100715372 0.01 ENST00000370131.3
ENST00000370132.4
DBT
dihydrolipoamide branched chain transacylase E2
chr2_-_26101374 0.01 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr8_+_48920960 0.01 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr6_-_42419649 0.01 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr1_+_113615794 0.01 ENST00000361127.5
LRIG2
leucine-rich repeats and immunoglobulin-like domains 2
chr15_-_72410109 0.01 ENST00000564571.1
MYO9A
myosin IXA
chr7_+_77469439 0.01 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr20_-_58515344 0.01 ENST00000370996.3
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr15_-_34394119 0.01 ENST00000256545.4
EMC7
ER membrane protein complex subunit 7
chr5_-_140998616 0.01 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr12_-_51420128 0.01 ENST00000262051.7
ENST00000547732.1
ENST00000262052.5
ENST00000546488.1
ENST00000550714.1
ENST00000548193.1
ENST00000547579.1
ENST00000546743.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr4_-_159593179 0.01 ENST00000379205.4
C4orf46
chromosome 4 open reading frame 46
chr1_+_62902308 0.01 ENST00000339950.4
USP1
ubiquitin specific peptidase 1
chr5_+_49961727 0.01 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_64684672 0.00 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr2_-_25475120 0.00 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr8_-_89339705 0.00 ENST00000286614.6
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr3_+_101292939 0.00 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP
PEST proteolytic signal containing nuclear protein

Network of associatons between targets according to the STRING database.

First level regulatory network of UGACCUA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)