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Illumina Body Map 2, young vs old

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Results for VAX2_RHOXF2

Z-value: 0.49

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
ENSG00000116035.2 ventral anterior homeobox 2
ENSG00000131721.4 Rhox homeobox family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RHOXF2hg19_v2_chrX_+_119292467_119292467-0.494.0e-03Click!
VAX2hg19_v2_chr2_+_71127699_711277440.105.8e-01Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89340242 3.03 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_+_90248739 2.83 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr9_+_125132803 2.23 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_125133315 2.08 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_+_92261516 1.76 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr6_+_26365443 1.64 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr6_+_26402517 1.60 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr7_+_50348268 1.55 ENST00000438033.1
ENST00000439701.1
IKAROS family zinc finger 1 (Ikaros)
chrX_+_135730297 1.52 ENST00000370629.2
CD40 ligand
chr2_-_89292422 1.52 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr6_+_26365387 1.50 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
butyrophilin, subfamily 3, member A2
chr1_+_62439037 1.46 ENST00000545929.1
InaD-like (Drosophila)
chr6_+_26402465 1.45 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chr2_+_90043607 1.42 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr14_+_22564294 1.40 ENST00000390452.2
T cell receptor delta variable 1
chr15_+_96904487 1.37 ENST00000600790.1
Uncharacterized protein
chrX_+_135730373 1.36 ENST00000370628.2
CD40 ligand
chr9_+_125133467 1.31 ENST00000426608.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_9760482 1.31 ENST00000229402.3
killer cell lectin-like receptor subfamily B, member 1
chr2_-_89597542 1.20 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr3_+_157154578 1.13 ENST00000295927.3
pentraxin 3, long
chr6_+_130339710 1.04 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr14_+_22670455 1.03 ENST00000390460.1
T cell receptor alpha variable 26-2
chr5_+_66300464 0.89 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr4_-_25865159 0.87 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_-_95166841 0.86 ENST00000262551.4
osteoglycin
chr7_+_142495131 0.83 ENST00000390419.1
T cell receptor beta joining 2-7
chr7_+_115862858 0.75 ENST00000393481.2
testis derived transcript (3 LIM domains)
chr4_+_169418195 0.74 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr10_-_92681033 0.74 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_17171817 0.74 ENST00000377833.4
cubilin (intrinsic factor-cobalamin receptor)
chr4_-_74486217 0.73 ENST00000335049.5
ENST00000307439.5
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_40201954 0.69 ENST00000511121.1
ras homolog family member H
chr12_+_131438496 0.68 ENST00000543826.1
G protein-coupled receptor 133
chr2_-_40680578 0.68 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr9_-_95166976 0.66 ENST00000447356.1
osteoglycin
chr4_+_169418255 0.66 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr4_-_74486347 0.66 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr5_+_66300446 0.65 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr16_+_12059050 0.63 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr4_-_74486109 0.63 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr7_-_92777606 0.62 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr17_-_40337470 0.62 ENST00000293330.1
hypocretin (orexin) neuropeptide precursor
chr14_+_22465771 0.60 ENST00000390445.2
T cell receptor alpha variable 17
chr12_+_131438443 0.60 ENST00000261654.5
G protein-coupled receptor 133
chrX_+_72783026 0.57 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr2_+_149402989 0.53 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_36001113 0.51 ENST00000434389.1
dermokine
chr6_+_26440700 0.50 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr15_+_74218787 0.49 ENST00000261921.7
lysyl oxidase-like 1
chr1_-_92952433 0.49 ENST00000294702.5
growth factor independent 1 transcription repressor
chr7_+_99717230 0.49 ENST00000262932.3
canopy FGF signaling regulator 4
chr4_+_151503077 0.48 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr4_+_26324474 0.48 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_107729887 0.45 ENST00000525815.1
solute carrier family 35, member F2
chr11_-_107729504 0.45 ENST00000265836.7
solute carrier family 35, member F2
chr18_-_67624160 0.44 ENST00000581982.1
ENST00000280200.4
CD226 molecule
chr12_-_10022735 0.44 ENST00000228438.2
C-type lectin domain family 2, member B
chr8_-_1922789 0.44 ENST00000521498.1
RP11-439C15.4
chr16_+_53133070 0.41 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr9_-_3469181 0.41 ENST00000366116.2
Uncharacterized protein
chr11_-_117747607 0.41 ENST00000540359.1
ENST00000539526.1
FXYD domain containing ion transport regulator 6
chr9_+_131062367 0.40 ENST00000601297.1
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr4_-_186696561 0.40 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
sorbin and SH3 domain containing 2
chr10_-_17171785 0.40 ENST00000377823.1
cubilin (intrinsic factor-cobalamin receptor)
chr19_+_50016610 0.40 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_107729287 0.39 ENST00000375682.4
solute carrier family 35, member F2
chr9_-_95166884 0.39 ENST00000375561.5
osteoglycin
chr10_+_18549645 0.37 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr19_-_52307357 0.37 ENST00000594900.1
formyl peptide receptor 1
chr14_-_21994337 0.36 ENST00000537235.1
ENST00000450879.2
spalt-like transcription factor 2
chr2_-_214016314 0.35 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr11_-_117747434 0.34 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chrX_-_77225135 0.32 ENST00000458128.1
phosphoglycerate mutase family member 4
chr6_+_167536230 0.32 ENST00000341935.5
ENST00000349984.4
chemokine (C-C motif) receptor 6
chr11_-_117748138 0.32 ENST00000527717.1
FXYD domain containing ion transport regulator 6
chr4_-_68829144 0.31 ENST00000508048.1
transmembrane protease, serine 11A
chr19_+_12175535 0.31 ENST00000550826.1
zinc finger protein 844
chr2_+_169926047 0.28 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
dehydrogenase/reductase (SDR family) member 9
chrX_-_21676442 0.27 ENST00000379499.2
kelch-like family member 34
chr6_-_133035185 0.27 ENST00000367928.4
vanin 1
chr6_-_137494775 0.26 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
interleukin 22 receptor, alpha 2
chr9_-_5339873 0.26 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr7_-_99716914 0.26 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_142494920 0.25 ENST00000390418.1
T cell receptor beta joining 2-6
chr3_-_191000172 0.25 ENST00000427544.2
urotensin 2B
chr14_+_72399833 0.25 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr17_+_48823896 0.25 ENST00000511974.1
LUC7-like 3 (S. cerevisiae)
chr15_+_58430368 0.24 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr5_-_149829314 0.24 ENST00000407193.1
ribosomal protein S14
chr7_+_37723336 0.24 ENST00000450180.1
G protein-coupled receptor 141
chr5_-_149829244 0.23 ENST00000312037.5
ribosomal protein S14
chr16_-_28608364 0.23 ENST00000533150.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr18_-_67623906 0.23 ENST00000583955.1
CD226 molecule
chr10_+_99205894 0.22 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr15_-_37393406 0.22 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr4_-_186696425 0.22 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr13_+_36050881 0.21 ENST00000537702.1
neurobeachin
chr14_+_101359265 0.21 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr4_-_138453559 0.21 ENST00000511115.1
protocadherin 18
chr6_-_33663474 0.21 ENST00000594414.1
SBP1; Uncharacterized protein
chr12_+_26348246 0.20 ENST00000422622.2
sarcospan
chr1_+_225600404 0.20 ENST00000366845.2
AC092811.1
chr17_-_41466555 0.18 ENST00000586231.1
long intergenic non-protein coding RNA 910
chr15_-_98417780 0.18 ENST00000503874.3
long intergenic non-protein coding RNA 923
chr11_-_62521614 0.17 ENST00000527994.1
ENST00000394807.3
zinc finger and BTB domain containing 3
chr14_-_20923195 0.17 ENST00000206542.4
O-sialoglycoprotein endopeptidase
chr1_+_160370344 0.17 ENST00000368061.2
VANGL planar cell polarity protein 2
chr10_+_90660832 0.17 ENST00000371924.1
STAM binding protein-like 1
chr19_+_12175504 0.16 ENST00000439326.3
zinc finger protein 844
chr15_+_58430567 0.16 ENST00000536493.1
aquaporin 9
chr4_-_186696515 0.16 ENST00000456596.1
ENST00000414724.1
sorbin and SH3 domain containing 2
chr5_+_121297650 0.16 ENST00000339397.4
serum response factor binding protein 1
chr3_+_152552685 0.16 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr9_+_12693336 0.15 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr17_-_39203519 0.15 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr1_+_46972668 0.14 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr4_-_69111401 0.14 ENST00000332644.5
transmembrane protease, serine 11B
chr4_+_159727272 0.14 ENST00000379346.3
folliculin interacting protein 2
chr10_+_99205959 0.14 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr12_-_50643664 0.13 ENST00000550592.1
LIM domain and actin binding 1
chr10_-_50396407 0.13 ENST00000374153.2
ENST00000374151.3
chromosome 10 open reading frame 128
chr3_+_158519654 0.13 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr7_+_148936732 0.13 ENST00000335870.2
zinc finger protein 212
chr14_+_56584414 0.12 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr20_-_33735070 0.12 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr7_-_44122063 0.12 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr1_+_54569968 0.12 ENST00000391366.1
Uncharacterized protein
chr20_-_50722183 0.11 ENST00000371523.4
ZFP64 zinc finger protein
chr20_+_43990576 0.11 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr20_+_56136136 0.11 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_+_48823975 0.11 ENST00000513969.1
ENST00000503728.1
LUC7-like 3 (S. cerevisiae)
chr5_-_149829294 0.11 ENST00000401695.3
ribosomal protein S14
chr4_+_80584903 0.10 ENST00000506460.1
RP11-452C8.1
chr16_-_30122717 0.10 ENST00000566613.1
glycerophosphodiester phosphodiesterase domain containing 3
chr17_-_39191107 0.10 ENST00000344363.5
keratin associated protein 1-3
chr18_-_33709268 0.09 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr2_+_113763031 0.09 ENST00000259211.6
interleukin 36, alpha
chr14_+_32547434 0.09 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr4_-_138453606 0.09 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr12_-_118796910 0.09 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr12_-_118797475 0.09 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr5_+_176811431 0.09 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr18_-_67624412 0.08 ENST00000580335.1
CD226 molecule
chr7_+_6655225 0.08 ENST00000457543.3
zinc finger protein 853
chr12_+_26348429 0.08 ENST00000242729.2
sarcospan
chr19_-_46088068 0.08 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr12_-_6233828 0.07 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr16_-_28608424 0.07 ENST00000335715.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr18_+_47087390 0.07 ENST00000583083.1
lipase, endothelial
chr19_+_36632485 0.07 ENST00000586963.1
calpain, small subunit 1
chr5_-_89770582 0.06 ENST00000316610.6
metallo-beta-lactamase domain containing 2
chr1_+_153747746 0.06 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chr5_+_96840389 0.05 ENST00000504012.1
RP11-1E3.1
chr14_+_67831576 0.05 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr15_+_49462434 0.05 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
galactokinase 2
chr7_-_99716952 0.05 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_-_36050819 0.05 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr7_-_99717463 0.04 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_+_64798826 0.04 ENST00000540203.1
exportin, tRNA
chr21_+_17443434 0.04 ENST00000400178.2
long intergenic non-protein coding RNA 478
chr11_-_111794446 0.03 ENST00000527950.1
crystallin, alpha B
chr14_+_20923350 0.03 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr3_+_185431080 0.03 ENST00000296270.1
chromosome 3 open reading frame 65
chr5_+_140557371 0.02 ENST00000239444.2
protocadherin beta 8
chr19_+_36632204 0.02 ENST00000592354.1
calpain, small subunit 1
chr4_-_68829226 0.02 ENST00000396188.2
transmembrane protease, serine 11A
chr16_+_72088376 0.02 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr12_-_118796971 0.02 ENST00000542902.1
TAO kinase 3
chr15_-_49912944 0.02 ENST00000559905.1
family with sequence similarity 227, member B
chr3_-_112127981 0.02 ENST00000486726.2
RP11-231E6.1
chr19_+_107471 0.02 ENST00000585993.1
olfactory receptor, family 4, subfamily F, member 17
chr2_+_103089756 0.01 ENST00000295269.4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr12_-_10955226 0.01 ENST00000240687.2
taste receptor, type 2, member 7
chr17_-_71258491 0.01 ENST00000397671.1
cleavage and polyadenylation specific factor 4-like
chr19_-_3557570 0.01 ENST00000355415.2
major facilitator superfamily domain containing 12
chr6_-_82957433 0.00 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr14_-_39639523 0.00 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
trafficking protein particle complex 6B
chr6_-_138866823 0.00 ENST00000342260.5
NHS-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 6.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 1.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.5 GO:0018277 protein deamination(GO:0018277)
0.1 2.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.8 GO:0019532 oxalate transport(GO:0019532)
0.1 1.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 1.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 7.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 5.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 2.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.4 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 7.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 5.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1