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Illumina Body Map 2, young vs old

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Results for VAX2_RHOXF2

Z-value: 0.49

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Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
VAX2
ENSG00000116035.2 ventral anterior homeobox 2
RHOXF2
ENSG00000131721.4 Rhox homeobox family member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RHOXF2hg19_v2_chrX_+_119292467_119292467-0.494.0e-03Click!
VAX2hg19_v2_chr2_+_71127699_711277440.105.8e-01Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89340242 3.03 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr2_+_90248739 2.83 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr9_+_125132803 2.23 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_125133315 2.08 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr8_+_92261516 1.76 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr6_+_26365443 1.64 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr6_+_26402517 1.60 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr7_+_50348268 1.55 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chrX_+_135730297 1.52 ENST00000370629.2
CD40LG
CD40 ligand
chr2_-_89292422 1.52 ENST00000495489.1
IGKV1-8
immunoglobulin kappa variable 1-8
chr6_+_26365387 1.50 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_+_62439037 1.46 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_+_26402465 1.45 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_+_90043607 1.42 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr14_+_22564294 1.40 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr15_+_96904487 1.37 ENST00000600790.1
AC087477.1
Uncharacterized protein
chrX_+_135730373 1.36 ENST00000370628.2
CD40LG
CD40 ligand
chr9_+_125133467 1.31 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_9760482 1.31 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr2_-_89597542 1.20 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr3_+_157154578 1.13 ENST00000295927.3
PTX3
pentraxin 3, long
chr6_+_130339710 1.04 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr14_+_22670455 1.03 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr5_+_66300464 0.89 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_25865159 0.87 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_-_95166841 0.86 ENST00000262551.4
OGN
osteoglycin
chr7_+_142495131 0.83 ENST00000390419.1
TRBJ2-7
T cell receptor beta joining 2-7
chr7_+_115862858 0.75 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr4_+_169418195 0.74 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr10_-_92681033 0.74 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_17171817 0.74 ENST00000377833.4
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr4_-_74486217 0.73 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_40201954 0.69 ENST00000511121.1
RHOH
ras homolog family member H
chr12_+_131438496 0.68 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr2_-_40680578 0.68 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr9_-_95166976 0.66 ENST00000447356.1
OGN
osteoglycin
chr4_+_169418255 0.66 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr4_-_74486347 0.66 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr5_+_66300446 0.65 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr16_+_12059050 0.63 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_-_74486109 0.63 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_-_92777606 0.62 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr17_-_40337470 0.62 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr14_+_22465771 0.60 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr12_+_131438443 0.60 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chrX_+_72783026 0.57 ENST00000373504.6
ENST00000373502.5
CHIC1
cysteine-rich hydrophobic domain 1
chr2_+_149402989 0.53 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr19_-_36001113 0.51 ENST00000434389.1
DMKN
dermokine
chr6_+_26440700 0.50 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr15_+_74218787 0.49 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr1_-_92952433 0.49 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr7_+_99717230 0.49 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr4_+_151503077 0.48 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr4_+_26324474 0.48 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_107729887 0.45 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr11_-_107729504 0.45 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr18_-_67624160 0.44 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr12_-_10022735 0.44 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_-_1922789 0.44 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr16_+_53133070 0.41 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_3469181 0.41 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr11_-_117747607 0.41 ENST00000540359.1
ENST00000539526.1
FXYD6
FXYD domain containing ion transport regulator 6
chr9_+_131062367 0.40 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr4_-_186696561 0.40 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr10_-_17171785 0.40 ENST00000377823.1
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr19_+_50016610 0.40 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr11_-_107729287 0.39 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr9_-_95166884 0.39 ENST00000375561.5
OGN
osteoglycin
chr10_+_18549645 0.37 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr19_-_52307357 0.37 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr14_-_21994337 0.36 ENST00000537235.1
ENST00000450879.2
SALL2
spalt-like transcription factor 2
chr2_-_214016314 0.35 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_-_117747434 0.34 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chrX_-_77225135 0.32 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr6_+_167536230 0.32 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr11_-_117748138 0.32 ENST00000527717.1
FXYD6
FXYD domain containing ion transport regulator 6
chr4_-_68829144 0.31 ENST00000508048.1
TMPRSS11A
transmembrane protease, serine 11A
chr19_+_12175535 0.31 ENST00000550826.1
ZNF844
zinc finger protein 844
chr2_+_169926047 0.28 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chrX_-_21676442 0.27 ENST00000379499.2
KLHL34
kelch-like family member 34
chr6_-_133035185 0.27 ENST00000367928.4
VNN1
vanin 1
chr6_-_137494775 0.26 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2
interleukin 22 receptor, alpha 2
chr9_-_5339873 0.26 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr7_-_99716914 0.26 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_142494920 0.25 ENST00000390418.1
TRBJ2-6
T cell receptor beta joining 2-6
chr3_-_191000172 0.25 ENST00000427544.2
UTS2B
urotensin 2B
chr14_+_72399833 0.25 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr17_+_48823896 0.25 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr15_+_58430368 0.24 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr5_-_149829314 0.24 ENST00000407193.1
RPS14
ribosomal protein S14
chr7_+_37723336 0.24 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr5_-_149829244 0.23 ENST00000312037.5
RPS14
ribosomal protein S14
chr16_-_28608364 0.23 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr18_-_67623906 0.23 ENST00000583955.1
CD226
CD226 molecule
chr10_+_99205894 0.22 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr15_-_37393406 0.22 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr4_-_186696425 0.22 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr13_+_36050881 0.21 ENST00000537702.1
NBEA
neurobeachin
chr14_+_101359265 0.21 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr4_-_138453559 0.21 ENST00000511115.1
PCDH18
protocadherin 18
chr6_-_33663474 0.21 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr12_+_26348246 0.20 ENST00000422622.2
SSPN
sarcospan
chr1_+_225600404 0.20 ENST00000366845.2
AC092811.1
AC092811.1
chr17_-_41466555 0.18 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chr15_-_98417780 0.18 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr11_-_62521614 0.17 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr14_-_20923195 0.17 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr1_+_160370344 0.17 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_+_90660832 0.17 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr19_+_12175504 0.16 ENST00000439326.3
ZNF844
zinc finger protein 844
chr15_+_58430567 0.16 ENST00000536493.1
AQP9
aquaporin 9
chr4_-_186696515 0.16 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr5_+_121297650 0.16 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chr3_+_152552685 0.16 ENST00000305097.3
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr9_+_12693336 0.15 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr17_-_39203519 0.15 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr1_+_46972668 0.14 ENST00000371956.4
ENST00000360032.3
DMBX1
diencephalon/mesencephalon homeobox 1
chr4_-_69111401 0.14 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr4_+_159727272 0.14 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr10_+_99205959 0.14 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr12_-_50643664 0.13 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr10_-_50396407 0.13 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr3_+_158519654 0.13 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr7_+_148936732 0.13 ENST00000335870.2
ZNF212
zinc finger protein 212
chr14_+_56584414 0.12 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr20_-_33735070 0.12 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr7_-_44122063 0.12 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr1_+_54569968 0.12 ENST00000391366.1
AL161915.1
Uncharacterized protein
chr20_-_50722183 0.11 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr20_+_43990576 0.11 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr20_+_56136136 0.11 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_+_48823975 0.11 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr5_-_149829294 0.11 ENST00000401695.3
RPS14
ribosomal protein S14
chr4_+_80584903 0.10 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr16_-_30122717 0.10 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr17_-_39191107 0.10 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr18_-_33709268 0.09 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr2_+_113763031 0.09 ENST00000259211.6
IL36A
interleukin 36, alpha
chr14_+_32547434 0.09 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr4_-_138453606 0.09 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr12_-_118796910 0.09 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr12_-_118797475 0.09 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr5_+_176811431 0.09 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr18_-_67624412 0.08 ENST00000580335.1
CD226
CD226 molecule
chr7_+_6655225 0.08 ENST00000457543.3
ZNF853
zinc finger protein 853
chr12_+_26348429 0.08 ENST00000242729.2
SSPN
sarcospan
chr19_-_46088068 0.08 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr12_-_6233828 0.07 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr16_-_28608424 0.07 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr18_+_47087390 0.07 ENST00000583083.1
LIPG
lipase, endothelial
chr19_+_36632485 0.07 ENST00000586963.1
CAPNS1
calpain, small subunit 1
chr5_-_89770582 0.06 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr1_+_153747746 0.06 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr5_+_96840389 0.05 ENST00000504012.1
RP11-1E3.1
RP11-1E3.1
chr14_+_67831576 0.05 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr15_+_49462434 0.05 ENST00000558145.1
ENST00000543495.1
ENST00000544523.1
ENST00000560138.1
GALK2
galactokinase 2
chr7_-_99716952 0.05 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_-_36050819 0.05 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr7_-_99717463 0.04 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_+_64798826 0.04 ENST00000540203.1
XPOT
exportin, tRNA
chr21_+_17443434 0.04 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr11_-_111794446 0.03 ENST00000527950.1
CRYAB
crystallin, alpha B
chr14_+_20923350 0.03 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr3_+_185431080 0.03 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr5_+_140557371 0.02 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr19_+_36632204 0.02 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr4_-_68829226 0.02 ENST00000396188.2
TMPRSS11A
transmembrane protease, serine 11A
chr16_+_72088376 0.02 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr12_-_118796971 0.02 ENST00000542902.1
TAOK3
TAO kinase 3
chr15_-_49912944 0.02 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr3_-_112127981 0.02 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr19_+_107471 0.02 ENST00000585993.1
OR4F17
olfactory receptor, family 4, subfamily F, member 17
chr2_+_103089756 0.01 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr12_-_10955226 0.01 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr17_-_71258491 0.01 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr19_-_3557570 0.01 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr6_-_82957433 0.00 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr14_-_39639523 0.00 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
TRAPPC6B
trafficking protein particle complex 6B
chr6_-_138866823 0.00 ENST00000342260.5
NHSL1
NHS-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 6.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 1.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 0.5 GO:0018277 protein deamination(GO:0018277)
0.1 2.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.6 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 1.8 GO:0019532 oxalate transport(GO:0019532)
0.1 1.1 GO:0015889 cobalamin transport(GO:0015889)
0.1 1.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.5 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 7.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 5.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 2.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.1 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.1 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.4 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 7.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0000150 recombinase activity(GO:0000150)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 5.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1