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Illumina Body Map 2, young vs old

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Results for VENTX

Z-value: 0.20

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Transcription factors associated with VENTX

Gene Symbol Gene ID Gene Info
ENSG00000151650.7 VENT homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_1350509080.241.8e-01Click!

Activity profile of VENTX motif

Sorted Z-values of VENTX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_107712173 4.12 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr4_-_155511887 3.99 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr3_+_32859510 3.28 ENST00000383763.5
tripartite motif containing 71, E3 ubiquitin protein ligase
chr11_+_123430948 3.14 ENST00000529432.1
ENST00000534764.1
GRAM domain containing 1B
chr14_+_22433675 2.91 ENST00000390442.3
T cell receptor alpha variable 12-3
chr4_+_105828492 2.69 ENST00000506148.1
RP11-556I14.1
chr14_+_92789498 2.67 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_59000815 2.63 ENST00000262717.4
cadherin 20, type 2
chr8_+_50824233 2.63 ENST00000522124.1
syntrophin, gamma 1
chr21_+_39644395 2.62 ENST00000398934.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr3_+_186383741 2.60 ENST00000232003.4
histidine-rich glycoprotein
chrX_+_130192318 2.43 ENST00000370922.1
Rho GTPase activating protein 36
chr18_+_29171689 2.38 ENST00000237014.3
transthyretin
chr6_+_155538093 2.35 ENST00000462408.2
T-cell lymphoma invasion and metastasis 2
chr16_-_51185149 2.31 ENST00000566102.1
ENST00000541611.1
spalt-like transcription factor 1
chr16_-_51185172 2.27 ENST00000251020.4
spalt-like transcription factor 1
chr10_-_33405600 2.24 ENST00000414308.1
RP11-342D11.3
chrX_+_130192216 2.20 ENST00000276211.5
Rho GTPase activating protein 36
chr6_+_140175987 2.20 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
chr6_+_78400375 2.16 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chrX_+_135730297 2.15 ENST00000370629.2
CD40 ligand
chr16_-_67517716 2.12 ENST00000290953.2
agouti related protein homolog (mouse)
chr12_+_111471828 2.10 ENST00000261726.6
cut-like homeobox 2
chr2_+_135596180 2.08 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr17_+_44701402 2.07 ENST00000575068.1
N-ethylmaleimide-sensitive factor
chr3_+_134514093 2.01 ENST00000398015.3
EPH receptor B1
chr17_+_68100989 1.96 ENST00000585558.1
ENST00000392670.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_68101117 1.92 ENST00000587698.1
ENST00000587892.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr2_+_135596106 1.89 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr18_+_76740189 1.74 ENST00000537592.2
ENST00000575389.2
spalt-like transcription factor 3
chr14_-_75083313 1.69 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr2_+_171034646 1.67 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr15_+_34260921 1.64 ENST00000560035.1
cholinergic receptor, muscarinic 5
chrX_+_78003204 1.62 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr12_-_45269251 1.60 ENST00000553120.1
NEL-like 2 (chicken)
chr12_+_70219052 1.59 ENST00000552032.2
ENST00000547771.2
myelin regulatory factor-like
chr16_+_70207686 1.58 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
C-type lectin domain family 18, member C
chr15_+_54305101 1.58 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr16_+_69984810 1.57 ENST00000393701.2
ENST00000568461.1
C-type lectin domain family 18, member A
chr17_-_29645836 1.56 ENST00000578584.1
CTD-2370N5.3
chr8_+_31496809 1.55 ENST00000518104.1
ENST00000519301.1
neuregulin 1
chr2_-_88285309 1.54 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr2_+_166152283 1.54 ENST00000375427.2
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_8666126 1.52 ENST00000299665.2
C-type lectin domain family 4, member D
chr1_+_40713573 1.51 ENST00000372766.3
transmembrane and coiled-coil domains 2
chrX_+_135730373 1.51 ENST00000370628.2
CD40 ligand
chr14_+_22670455 1.51 ENST00000390460.1
T cell receptor alpha variable 26-2
chr16_+_69985083 1.49 ENST00000288040.6
ENST00000449317.2
C-type lectin domain family 18, member A
chr12_+_52695617 1.49 ENST00000293525.5
keratin 86
chr14_+_23709555 1.46 ENST00000430154.2
chromosome 14 open reading frame 164
chr13_-_67802549 1.45 ENST00000328454.5
ENST00000377865.2
protocadherin 9
chr11_-_72070206 1.44 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_+_244515930 1.44 ENST00000366537.1
ENST00000308105.4
chromosome 1 open reading frame 100
chr8_+_92261516 1.43 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chrX_+_106163626 1.41 ENST00000336803.1
claudin 2
chr3_-_57233966 1.40 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr16_-_74455290 1.38 ENST00000339953.5
C-type lectin domain family 18, member B
chr3_-_72149448 1.36 ENST00000498432.1
long intergenic non-protein coding RNA 877
chr12_-_120241187 1.34 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr12_+_48722763 1.30 ENST00000335017.1
H1 histone family, member N, testis-specific
chr22_+_42834029 1.27 ENST00000428765.1
CTA-126B4.7
chr15_-_33180439 1.25 ENST00000559610.1
formin 1
chr7_-_107880508 1.25 ENST00000425651.2
neuronal cell adhesion molecule
chr4_+_86748898 1.17 ENST00000509300.1
Rho GTPase activating protein 24
chr6_-_66417107 1.15 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr2_+_87135076 1.14 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr11_+_22359562 1.13 ENST00000263160.3
solute carrier family 17 (vesicular glutamate transporter), member 6
chr18_-_74207146 1.12 ENST00000443185.2
zinc finger protein 516
chr12_-_101604185 1.12 ENST00000536262.2
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr2_+_169757750 1.11 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr14_+_22309368 1.10 ENST00000390433.1
T cell receptor alpha variable 12-1
chr9_-_23825956 1.09 ENST00000397312.2
ELAV like neuron-specific RNA binding protein 2
chr17_+_43239231 1.04 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr12_+_81110684 1.04 ENST00000228644.3
myogenic factor 5
chrX_-_21676442 1.03 ENST00000379499.2
kelch-like family member 34
chr14_+_65171315 1.02 ENST00000394691.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_65171099 1.01 ENST00000247226.7
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_+_25205628 1.00 ENST00000554942.1
lymphoid-restricted membrane protein
chr3_-_72149553 0.98 ENST00000468646.2
ENST00000464271.1
long intergenic non-protein coding RNA 877
chr12_-_53012343 0.95 ENST00000305748.3
keratin 73
chr3_-_27764190 0.95 ENST00000537516.1
eomesodermin
chr14_+_22951993 0.94 ENST00000390485.1
T cell receptor alpha joining 53
chr9_+_133539981 0.94 ENST00000253008.2
PR domain containing 12
chr6_+_34204642 0.93 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chrX_+_123097014 0.92 ENST00000394478.1
stromal antigen 2
chr1_-_102312517 0.91 ENST00000338858.5
olfactomedin 3
chr14_+_65170820 0.91 ENST00000555982.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_+_25205155 0.91 ENST00000550945.1
lymphoid-restricted membrane protein
chr22_-_40929812 0.91 ENST00000422851.1
megakaryoblastic leukemia (translocation) 1
chr12_-_2113583 0.90 ENST00000397173.4
ENST00000280665.6
decapping mRNA 1B
chr4_+_105828537 0.89 ENST00000515649.1
RP11-556I14.1
chr4_-_176733377 0.87 ENST00000505375.1
glycoprotein M6A
chr8_+_24298597 0.86 ENST00000380789.1
ADAM metallopeptidase domain 7
chr10_+_114043493 0.85 ENST00000369422.3
tectorin beta
chr12_+_25205446 0.82 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr1_-_190446759 0.82 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr10_+_94594351 0.82 ENST00000371552.4
exocyst complex component 6
chr17_-_10372875 0.81 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr7_+_18535321 0.80 ENST00000413380.1
ENST00000430454.1
histone deacetylase 9
chr10_-_74714533 0.80 ENST00000373032.3
phospholipase A2, group XIIB
chr4_-_122148620 0.80 ENST00000509841.1
TNFAIP3 interacting protein 3
chr8_+_24298531 0.79 ENST00000175238.6
ADAM metallopeptidase domain 7
chr2_-_166060382 0.79 ENST00000409101.3
sodium channel, voltage-gated, type III, alpha subunit
chr18_-_53804580 0.79 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
RP11-456O19.4
chr7_+_90338547 0.78 ENST00000446790.1
cyclin-dependent kinase 14
chr1_-_102312600 0.78 ENST00000359814.3
olfactomedin 3
chr11_+_7618413 0.77 ENST00000528883.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_+_105936982 0.77 ENST00000418562.1
ring finger protein 128, E3 ubiquitin protein ligase
chr1_+_43291220 0.77 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr11_-_3859089 0.76 ENST00000396979.1
ras homolog family member G
chr14_+_22951276 0.74 ENST00000390484.1
T cell receptor alpha joining 54
chr9_+_136501478 0.74 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr17_-_47045949 0.74 ENST00000357424.2
gastric inhibitory polypeptide
chr4_-_26492076 0.74 ENST00000295589.3
cholecystokinin A receptor
chr5_+_43121698 0.74 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
zinc finger protein 131
chr15_+_34261089 0.73 ENST00000383263.5
cholinergic receptor, muscarinic 5
chr1_-_114696472 0.72 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
synaptotagmin VI
chr7_-_104909435 0.72 ENST00000357311.3
SRSF protein kinase 2
chr6_+_43968306 0.71 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr3_-_157221380 0.70 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr8_+_107738240 0.69 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr20_-_50722183 0.69 ENST00000371523.4
ZFP64 zinc finger protein
chr10_-_62332357 0.69 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_37897735 0.69 ENST00000373389.5
zinc finger, AN1-type domain 3
chr17_+_43239191 0.69 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chr8_+_107738343 0.69 ENST00000521592.1
oxidation resistance 1
chr12_-_86650077 0.67 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr13_+_76378407 0.66 ENST00000447038.1
LIM domain 7
chr4_+_86749045 0.65 ENST00000514229.1
Rho GTPase activating protein 24
chr4_+_130017268 0.64 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr1_+_153747746 0.64 ENST00000368661.3
solute carrier family 27 (fatty acid transporter), member 3
chrY_-_13524717 0.63 ENST00000331172.6
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr2_+_45168875 0.62 ENST00000260653.3
SIX homeobox 3
chr13_+_76378305 0.62 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr4_-_168155169 0.62 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_-_156486120 0.62 ENST00000522693.1
hepatitis A virus cellular receptor 1
chr8_-_42358742 0.61 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr11_+_26495447 0.60 ENST00000531568.1
anoctamin 3
chr12_-_78934441 0.60 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
chr3_-_57260377 0.60 ENST00000495160.2
HESX homeobox 1
chr4_-_84035905 0.59 ENST00000311507.4
placenta-specific 8
chr4_+_129732467 0.59 ENST00000413543.2
jade family PHD finger 1
chr10_-_28571015 0.59 ENST00000375719.3
ENST00000375732.1
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_+_9834179 0.59 ENST00000498623.2
actin related protein 2/3 complex, subunit 4, 20kDa
chr5_-_130500922 0.59 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
histidine triad nucleotide binding protein 1
chr20_-_25371412 0.59 ENST00000339157.5
ENST00000376542.3
abhydrolase domain containing 12
chr5_+_1225470 0.58 ENST00000324642.3
ENST00000296821.4
solute carrier family 6 (neutral amino acid transporter), member 18
chr12_+_25205666 0.58 ENST00000547044.1
lymphoid-restricted membrane protein
chr13_+_76378357 0.56 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chrX_-_139587225 0.56 ENST00000370536.2
SRY (sex determining region Y)-box 3
chr7_+_18535346 0.55 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr3_+_9834227 0.55 ENST00000287613.7
ENST00000397261.3
actin related protein 2/3 complex, subunit 4, 20kDa
chr6_+_47749718 0.55 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
opsin 5
chr10_+_68685764 0.54 ENST00000361320.4
leucine rich repeat transmembrane neuronal 3
chrX_+_105937068 0.54 ENST00000324342.3
ring finger protein 128, E3 ubiquitin protein ligase
chr12_-_86650045 0.54 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr16_+_73420942 0.54 ENST00000554640.1
ENST00000562661.1
ENST00000561875.1
RP11-140I24.1
chr5_+_65222500 0.54 ENST00000511297.1
ENST00000506030.1
erbb2 interacting protein
chr20_+_42523336 0.51 ENST00000428529.1
RP5-1030M6.3
chr12_-_89746173 0.51 ENST00000308385.6
dual specificity phosphatase 6
chr12_-_89746264 0.50 ENST00000548755.1
dual specificity phosphatase 6
chr2_+_17997763 0.49 ENST00000281047.3
mesogenin 1
chr7_+_129984630 0.48 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr11_-_11374904 0.47 ENST00000528848.2
casein kinase 2, alpha 3 polypeptide
chr14_+_65453432 0.47 ENST00000246166.2
farnesyltransferase, CAAX box, beta
chr12_-_12674032 0.46 ENST00000298573.4
dual specificity phosphatase 16
chr13_-_26795840 0.44 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
ring finger protein (C3H2C3 type) 6
chr7_+_90338712 0.43 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr17_-_48785216 0.43 ENST00000285243.6
ankyrin repeat domain 40
chr12_-_122017542 0.42 ENST00000446152.2
lysine (K)-specific demethylase 2B
chr19_-_46088068 0.42 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr11_-_64684672 0.42 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr18_-_24237339 0.42 ENST00000580191.1
potassium channel tetramerization domain containing 1
chr12_-_122018114 0.40 ENST00000539394.1
lysine (K)-specific demethylase 2B
chr10_-_50603497 0.40 ENST00000374139.2
dorsal root ganglia homeobox
chr3_-_147123837 0.40 ENST00000462748.2
Zic family member 4
chr1_+_28527070 0.40 ENST00000596102.1
AL353354.2
chr8_-_116681221 0.39 ENST00000395715.3
trichorhinophalangeal syndrome I
chr4_-_46126093 0.38 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr1_+_153746683 0.38 ENST00000271857.2
solute carrier family 27 (fatty acid transporter), member 3
chr14_+_65182395 0.38 ENST00000554088.1
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_-_102591604 0.36 ENST00000329406.4
pro-melanin-concentrating hormone
chr14_+_74706150 0.36 ENST00000261980.2
visual system homeobox 2
chr4_-_84035868 0.34 ENST00000426923.2
ENST00000509973.1
placenta-specific 8
chr2_-_145277569 0.33 ENST00000303660.4
zinc finger E-box binding homeobox 2
chr2_+_149402989 0.33 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr3_+_156799587 0.32 ENST00000469196.1
RP11-6F2.5
chr9_+_117904097 0.32 ENST00000374016.1
deleted in esophageal cancer 1
chr17_-_38928414 0.30 ENST00000335552.4
keratin 26
chr1_+_226411319 0.30 ENST00000542034.1
ENST00000366810.5
Mix paired-like homeobox
chr8_-_116681123 0.30 ENST00000519674.1
trichorhinophalangeal syndrome I
chr4_+_123161120 0.29 ENST00000446180.1
KIAA1109
chr6_-_9977801 0.29 ENST00000316020.6
ENST00000491508.1
orofacial cleft 1 candidate 1
chr18_+_13465008 0.29 ENST00000593236.1
low density lipoprotein receptor class A domain containing 4
chr8_-_103425047 0.28 ENST00000520539.1
ubiquitin protein ligase E3 component n-recognin 5
chr8_+_26150628 0.27 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr12_-_122018346 0.27 ENST00000377069.4
lysine (K)-specific demethylase 2B
chr1_+_150337144 0.27 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
regulation of nuclear pre-mRNA domain containing 2
chr1_-_152061537 0.27 ENST00000368806.1
trichohyalin-like 1
chr5_-_79950775 0.26 ENST00000439211.2
dihydrofolate reductase

Network of associatons between targets according to the STRING database.

First level regulatory network of VENTX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.8 4.6 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.7 2.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.7 2.6 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.6 4.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 2.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 1.3 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 1.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 4.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.7 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.2 0.9 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.2 2.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 1.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 0.6 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.2 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 2.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 1.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 2.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.5 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.2 2.0 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.6 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 3.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 3.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.7 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.5 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.7 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 1.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.6 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 6.5 GO:0010107 potassium ion import(GO:0010107)
0.1 1.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.7 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 0.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 2.1 GO:0007614 short-term memory(GO:0007614)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 1.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 1.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.3 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 2.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 1.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 2.2 GO:0097186 amelogenesis(GO:0097186)
0.1 1.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 4.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 1.5 GO:0030900 forebrain development(GO:0030900)
0.0 1.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 1.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.1 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 3.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 5.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 1.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.8 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 3.0 GO:0070268 cornification(GO:0070268)
0.0 0.8 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.6 GO:0007530 sex determination(GO:0007530)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.5 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 4.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.6 GO:0016013 syntrophin complex(GO:0016013)
0.2 1.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.6 GO:0044305 calyx of Held(GO:0044305)
0.1 4.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.2 GO:0000800 lateral element(GO:0000800)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 2.6 GO:0036019 endolysosome(GO:0036019)
0.1 1.9 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 4.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.3 GO:0005884 actin filament(GO:0005884)
0.0 3.1 GO:0045095 keratin filament(GO:0045095)
0.0 3.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 3.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 3.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 4.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.3 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 2.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 2.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 6.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.7 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.2 2.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 2.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.6 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 3.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 3.3 GO:0035198 miRNA binding(GO:0035198)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 2.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 5.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.0 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 5.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 6.4 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.3 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 2.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 7.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 8.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation