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Illumina Body Map 2, young vs old

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Results for ZIC3_ZIC4

Z-value: 0.26

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Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ZIC3
ENSG00000156925.7 Zic family member 3
ZIC4
ENSG00000174963.13 Zic family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC4hg19_v2_chr3_-_147123837_147123920-0.193.1e-01Click!
ZIC3hg19_v2_chrX_+_136648643_136648711-0.134.8e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2182388 4.31 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr19_-_10024496 2.61 ENST00000593091.1
OLFM2
olfactomedin 2
chr3_+_148847371 2.46 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr5_+_75699149 2.42 ENST00000379730.3
IQGAP2
IQ motif containing GTPase activating protein 2
chr2_+_234627424 2.30 ENST00000373409.3
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr3_+_184097836 2.27 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr10_-_48416849 2.13 ENST00000249598.1
GDF2
growth differentiation factor 2
chr7_-_994302 2.12 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr11_+_66790816 2.10 ENST00000527043.1
SYT12
synaptotagmin XII
chr17_+_79761997 2.04 ENST00000400723.3
ENST00000570996.1
GCGR
glucagon receptor
chr2_+_234621551 2.03 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr5_+_75699040 2.00 ENST00000274364.6
IQGAP2
IQ motif containing GTPase activating protein 2
chr4_-_40631859 1.99 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr2_+_128180842 1.96 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr2_+_234637754 1.92 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_+_302918 1.89 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr7_+_65540780 1.82 ENST00000304874.9
ASL
argininosuccinate lyase
chr12_-_323689 1.78 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr17_-_6616678 1.77 ENST00000381074.4
ENST00000293800.6
ENST00000572352.1
ENST00000576323.1
ENST00000573648.1
SLC13A5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr2_-_73869508 1.76 ENST00000272425.3
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr1_-_159915386 1.73 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr8_+_1711918 1.72 ENST00000331222.4
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr7_+_65540853 1.69 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr16_+_56691911 1.59 ENST00000568475.1
MT1F
metallothionein 1F
chr9_-_130742792 1.58 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr4_+_166128735 1.50 ENST00000226725.6
KLHL2
kelch-like family member 2
chr3_+_143690640 1.45 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr2_+_219187871 1.42 ENST00000258362.3
PNKD
paroxysmal nonkinesigenic dyskinesia
chr3_+_184097905 1.37 ENST00000450923.1
CHRD
chordin
chr3_+_71803201 1.36 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr7_+_149571045 1.30 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr1_-_38273840 1.29 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr7_+_150758304 1.29 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr1_-_32801825 1.26 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr16_+_56691838 1.25 ENST00000394501.2
MT1F
metallothionein 1F
chr17_-_43045439 1.16 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr9_+_116638562 1.16 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr16_+_67465016 1.16 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr2_-_219925189 1.15 ENST00000295731.6
IHH
indian hedgehog
chr16_+_30996502 1.15 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
HSD3B7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr16_+_56691606 1.14 ENST00000334350.6
MT1F
metallothionein 1F
chr12_+_111471828 1.13 ENST00000261726.6
CUX2
cut-like homeobox 2
chr20_+_61340179 1.13 ENST00000370501.3
NTSR1
neurotensin receptor 1 (high affinity)
chr22_+_22735135 1.12 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr12_+_49932886 1.11 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr2_-_233792837 1.10 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr19_+_45409011 1.07 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE
apolipoprotein E
chr20_-_31172598 1.06 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr11_+_58938903 1.06 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chrX_+_152783131 1.05 ENST00000349466.2
ENST00000370186.1
ATP2B3
ATPase, Ca++ transporting, plasma membrane 3
chrX_+_51927919 1.01 ENST00000416960.1
MAGED4
melanoma antigen family D, 4
chr9_+_116638630 1.00 ENST00000452710.1
ENST00000374124.4
ZNF618
zinc finger protein 618
chr2_+_8822113 1.00 ENST00000396290.1
ENST00000331129.3
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr4_+_115519894 0.98 ENST00000507710.1
UGT8
UDP glycosyltransferase 8
chr1_+_2407754 0.97 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
PLCH2
phospholipase C, eta 2
chr10_+_134901388 0.95 ENST00000392607.3
GPR123
G protein-coupled receptor 123
chr4_-_106395135 0.94 ENST00000310267.7
PPA2
pyrophosphatase (inorganic) 2
chr2_+_105050794 0.93 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr5_+_43192311 0.92 ENST00000326035.2
NIM1
NIM1 serine/threonine protein kinase
chr4_-_106395197 0.91 ENST00000508518.1
ENST00000354147.3
ENST00000432483.2
ENST00000510015.1
ENST00000504028.1
ENST00000348706.5
ENST00000357415.4
ENST00000380004.2
ENST00000341695.5
PPA2
pyrophosphatase (inorganic) 2
chr11_+_69061594 0.91 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr17_-_7531121 0.89 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr16_+_2198604 0.89 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr12_+_56075330 0.88 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr17_+_7531281 0.88 ENST00000575729.1
ENST00000340624.5
SHBG
sex hormone-binding globulin
chr4_+_115519577 0.86 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr7_-_150020750 0.86 ENST00000539352.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_-_150020216 0.85 ENST00000477367.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr6_+_32006159 0.85 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_242755144 0.84 ENST00000428592.1
NEU4
sialidase 4
chr19_+_5823813 0.83 ENST00000303212.2
NRTN
neurturin
chr22_-_20368028 0.83 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr3_+_46919235 0.82 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr11_+_121322832 0.81 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr11_+_120081475 0.81 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr7_+_150026938 0.80 ENST00000343855.4
ZBED6CL
ZBED6 C-terminal like
chr7_+_150020363 0.80 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr12_-_132834281 0.80 ENST00000411988.2
ENST00000535228.1
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr19_-_40724246 0.80 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr7_-_150020814 0.80 ENST00000477871.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr22_+_48972118 0.79 ENST00000358295.5
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_-_88854518 0.78 ENST00000277865.4
GLUD1
glutamate dehydrogenase 1
chr13_-_99404875 0.78 ENST00000376503.5
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
chr3_+_11034403 0.77 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chrX_-_102319092 0.77 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr5_+_139055055 0.77 ENST00000511457.1
CXXC5
CXXC finger protein 5
chrX_+_2746850 0.76 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
GYG2
glycogenin 2
chr13_-_41111323 0.76 ENST00000595486.1
AL133318.1
Uncharacterized protein
chr16_+_2059872 0.75 ENST00000567649.1
NPW
neuropeptide W
chr15_+_31619013 0.75 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr7_+_150020329 0.74 ENST00000323078.7
LRRC61
leucine rich repeat containing 61
chr7_-_150020578 0.74 ENST00000478393.1
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr11_+_33563821 0.74 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr5_-_111091948 0.73 ENST00000447165.2
NREP
neuronal regeneration related protein
chr7_+_150758642 0.73 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr11_-_17555421 0.73 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr7_+_120969045 0.73 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr11_-_407103 0.73 ENST00000526395.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr6_+_97372734 0.72 ENST00000539200.1
KLHL32
kelch-like family member 32
chr17_-_38721711 0.71 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr15_+_65823092 0.71 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr6_+_32006042 0.71 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr1_+_38273988 0.71 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr17_-_27893990 0.70 ENST00000307201.4
ABHD15
abhydrolase domain containing 15
chr12_-_51785182 0.70 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr5_+_121647877 0.70 ENST00000514497.2
ENST00000261367.7
SNCAIP
synuclein, alpha interacting protein
chr8_-_80993010 0.69 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr1_+_33352036 0.69 ENST00000373467.3
HPCA
hippocalcin
chr2_+_79740118 0.68 ENST00000496558.1
ENST00000451966.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr6_+_33168597 0.68 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_+_139055021 0.68 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr2_+_10091815 0.67 ENST00000324907.9
GRHL1
grainyhead-like 1 (Drosophila)
chr11_+_129245796 0.66 ENST00000281437.4
BARX2
BARX homeobox 2
chr17_+_56160768 0.65 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr15_+_65822756 0.65 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr9_+_4490394 0.65 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr11_-_57004658 0.64 ENST00000606794.1
APLNR
apelin receptor
chr22_+_22723969 0.64 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr16_-_88717482 0.64 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr3_+_46923670 0.64 ENST00000427125.2
ENST00000430002.2
PTH1R
parathyroid hormone 1 receptor
chr6_+_33168637 0.64 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chrX_-_131352152 0.63 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr2_+_7865923 0.62 ENST00000417930.1
AC092580.4
AC092580.4
chr3_+_184098065 0.62 ENST00000348986.3
CHRD
chordin
chr2_+_10091783 0.62 ENST00000324883.5
GRHL1
grainyhead-like 1 (Drosophila)
chr10_-_126107482 0.62 ENST00000368845.5
ENST00000539214.1
OAT
ornithine aminotransferase
chr8_-_27462822 0.62 ENST00000522098.1
CLU
clusterin
chr17_-_19619917 0.62 ENST00000325411.5
ENST00000350657.5
ENST00000433844.2
SLC47A2
solute carrier family 47 (multidrug and toxin extrusion), member 2
chr6_+_150070831 0.62 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_+_75074385 0.61 ENST00000220003.9
CSK
c-src tyrosine kinase
chr11_-_65150103 0.61 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr19_-_1863567 0.61 ENST00000250916.4
KLF16
Kruppel-like factor 16
chr4_-_17513851 0.61 ENST00000281243.5
QDPR
quinoid dihydropteridine reductase
chr2_-_10220538 0.60 ENST00000381813.4
CYS1
cystin 1
chr17_-_70053866 0.60 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr3_-_123304017 0.60 ENST00000383657.5
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chrX_-_2847366 0.60 ENST00000381154.1
ARSD
arylsulfatase D
chr20_+_34203794 0.60 ENST00000374273.3
SPAG4
sperm associated antigen 4
chrX_+_2746818 0.60 ENST00000398806.3
GYG2
glycogenin 2
chr11_-_71159458 0.60 ENST00000355527.3
DHCR7
7-dehydrocholesterol reductase
chr7_-_100808394 0.60 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr11_+_22688615 0.59 ENST00000533363.1
GAS2
growth arrest-specific 2
chr4_+_166128836 0.59 ENST00000511305.1
KLHL2
kelch-like family member 2
chr19_+_19174795 0.59 ENST00000318596.7
SLC25A42
solute carrier family 25, member 42
chr22_+_43506747 0.59 ENST00000216115.2
BIK
BCL2-interacting killer (apoptosis-inducing)
chr1_+_150954493 0.58 ENST00000368947.4
ANXA9
annexin A9
chr16_-_10912605 0.58 ENST00000299866.8
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chr14_-_21994525 0.57 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr15_+_75074410 0.57 ENST00000439220.2
CSK
c-src tyrosine kinase
chr11_-_1036706 0.56 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr1_+_4714792 0.56 ENST00000378190.3
AJAP1
adherens junctions associated protein 1
chr7_-_5570229 0.56 ENST00000331789.5
ACTB
actin, beta
chr3_+_38179969 0.56 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
MYD88
myeloid differentiation primary response 88
chr1_+_146714291 0.55 ENST00000431239.1
ENST00000369259.3
ENST00000369258.4
ENST00000361293.5
CHD1L
chromodomain helicase DNA binding protein 1-like
chr6_+_150070857 0.55 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr10_+_88854926 0.55 ENST00000298784.1
ENST00000298786.4
FAM35A
family with sequence similarity 35, member A
chr2_-_67442409 0.55 ENST00000414404.1
ENST00000433133.1
AC078941.1
AC078941.1
chr2_+_115919049 0.55 ENST00000393147.2
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr2_+_37571845 0.54 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr4_-_17513604 0.54 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr17_+_39421591 0.54 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr5_+_176731572 0.54 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr10_+_85954377 0.54 ENST00000332904.3
ENST00000372117.3
CDHR1
cadherin-related family member 1
chr5_-_179498703 0.54 ENST00000522208.2
RNF130
ring finger protein 130
chr4_-_20985632 0.53 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr10_+_45455207 0.53 ENST00000334940.6
ENST00000374417.2
ENST00000340258.5
ENST00000427758.1
RASSF4
Ras association (RalGDS/AF-6) domain family member 4
chrX_-_128977364 0.53 ENST00000371064.3
ZDHHC9
zinc finger, DHHC-type containing 9
chr17_-_50235423 0.53 ENST00000340813.6
CA10
carbonic anhydrase X
chr3_+_125985620 0.53 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr16_+_89753070 0.52 ENST00000353379.7
ENST00000505473.1
ENST00000564192.1
CDK10
cyclin-dependent kinase 10
chr15_+_90728145 0.52 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr17_-_39191107 0.52 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr5_-_179499108 0.52 ENST00000521389.1
RNF130
ring finger protein 130
chr6_-_100016492 0.51 ENST00000369217.4
ENST00000369220.4
ENST00000482541.2
CCNC
cyclin C
chr5_-_76383133 0.51 ENST00000255198.2
ZBED3
zinc finger, BED-type containing 3
chr10_-_13390021 0.51 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr14_+_57046500 0.51 ENST00000261556.6
TMEM260
transmembrane protein 260
chr21_-_45682099 0.51 ENST00000270172.3
ENST00000418993.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr11_+_125774258 0.51 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr19_-_12992274 0.51 ENST00000592506.1
ENST00000222219.3
DNASE2
deoxyribonuclease II, lysosomal
chrX_-_128977781 0.50 ENST00000357166.6
ZDHHC9
zinc finger, DHHC-type containing 9
chr5_+_72509751 0.50 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr6_+_97372596 0.50 ENST00000369261.4
KLHL32
kelch-like family member 32
chr11_-_71159380 0.49 ENST00000525346.1
ENST00000531364.1
ENST00000529990.1
ENST00000527316.1
ENST00000407721.2
DHCR7
7-dehydrocholesterol reductase
chr2_-_242626127 0.49 ENST00000445261.1
DTYMK
deoxythymidylate kinase (thymidylate kinase)
chr19_+_49122785 0.49 ENST00000598088.1
SPHK2
sphingosine kinase 2
chr5_-_179499086 0.49 ENST00000261947.4
RNF130
ring finger protein 130
chr4_-_110624564 0.49 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
CASP6
caspase 6, apoptosis-related cysteine peptidase
chr1_+_38273818 0.48 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr19_-_36288740 0.48 ENST00000564335.1
ENST00000567313.1
ENST00000433059.1
AC002398.5
AC002398.5
chr7_-_44580861 0.48 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr1_-_235814048 0.47 ENST00000450593.1
ENST00000366598.4
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr22_+_29702572 0.47 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr11_-_67272794 0.47 ENST00000436757.2
ENST00000356404.3
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr10_-_79397547 0.47 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_115913222 0.46 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr3_+_186288454 0.46 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr17_+_27055798 0.46 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr7_-_100808843 0.46 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr2_+_37571717 0.46 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
1.4 4.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
1.2 3.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.0 6.3 GO:0006789 bilirubin conjugation(GO:0006789)
0.7 2.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.5 2.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.5 1.9 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.5 1.4 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.4 2.1 GO:0071344 diphosphate metabolic process(GO:0071344)
0.4 1.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.4 1.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.4 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 1.1 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
0.3 1.0 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.3 1.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3 0.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.3 1.4 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 0.8 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.3 0.8 GO:0042938 dipeptide transport(GO:0042938)
0.3 0.8 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.2 0.7 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.9 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 1.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.2 0.6 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.2 0.7 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 1.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 4.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.5 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 1.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 2.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 1.9 GO:0030091 protein repair(GO:0030091)
0.1 1.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.7 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 4.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.7 GO:1902075 cellular response to salt(GO:1902075)
0.1 0.7 GO:0015692 lead ion transport(GO:0015692)
0.1 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 1.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.8 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.6 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 1.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.6 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 1.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.7 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 1.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.1 0.6 GO:1902996 regulation of neuronal signal transduction(GO:1902847) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 0.3 GO:1903382 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.6 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.8 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 2.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0046618 drug export(GO:0046618)
0.1 1.3 GO:0002934 desmosome organization(GO:0002934)
0.1 0.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 0.1 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 1.0 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.2 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.7 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.2 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 3.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 3.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.9 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.3 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 1.1 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.3 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.1 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.8 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.6 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.3 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 1.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.4 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 1.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 1.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.6 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.4 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 1.6 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 1.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 3.0 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.3 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.6 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 2.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.4 GO:0007320 insemination(GO:0007320)
0.0 0.3 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318) clathrin-coated pit assembly(GO:1905224)
0.0 0.2 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.5 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.3 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 1.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.3 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.0 GO:1904170 septin ring assembly(GO:0000921) septin ring organization(GO:0031106) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0009967 positive regulation of signal transduction(GO:0009967)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.7 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 2.1 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.5 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.2 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 2.0 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 1.6 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.2 GO:0044301 climbing fiber(GO:0044301)
0.2 0.9 GO:0097196 Shu complex(GO:0097196)
0.2 1.1 GO:0032280 symmetric synapse(GO:0032280)
0.2 4.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 3.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.6 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.7 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 8.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.3 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 4.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 1.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 2.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0019867 outer membrane(GO:0019867)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 1.5 GO:0005903 brush border(GO:0005903)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.1 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.5 1.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.4 1.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 1.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.4 2.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.4 3.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 2.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 3.5 GO:0045545 syndecan binding(GO:0045545)
0.3 1.0 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.3 1.0 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.3 1.6 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.3 1.0 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 2.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.3 4.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 0.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 1.5 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.3 1.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 0.8 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.3 0.8 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 1.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.6 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 2.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 1.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 8.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.7 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.8 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.6 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.9 GO:0005497 androgen binding(GO:0005497)
0.1 0.6 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 2.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 4.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.1 GO:0005113 patched binding(GO:0005113)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.1 0.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.3 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 1.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 4.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 5.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.5 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 2.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 2.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition