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Illumina Body Map 2, young vs old

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Results for ZNF232

Z-value: 0.46

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Transcription factors associated with ZNF232

Gene Symbol Gene ID Gene Info
ZNF232
ENSG00000167840.9 zinc finger protein 232

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF232hg19_v2_chr17_-_5015129_50151870.261.6e-01Click!

Activity profile of ZNF232 motif

Sorted Z-values of ZNF232 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_142829162 1.98 ENST00000291009.3
PIP
prolactin-induced protein
chr1_-_79472365 1.16 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr16_-_14109841 1.04 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
CTD-2135D7.5
chr6_-_46922659 1.04 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr3_+_8543393 1.04 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543533 1.01 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_8543561 0.98 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr17_+_15943505 0.91 ENST00000442828.1
AC002553.1
Uncharacterized protein
chr4_-_88450612 0.89 ENST00000418378.1
ENST00000282470.6
SPARCL1
SPARC-like 1 (hevin)
chrY_+_15016725 0.82 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_+_39975455 0.75 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chrY_+_15016013 0.72 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr17_+_39975544 0.70 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_+_156105878 0.66 ENST00000508500.1
LMNA
lamin A/C
chr3_-_16738986 0.63 ENST00000426218.1
AC091493.2
AC091493.2
chr16_+_33605231 0.62 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_+_74425689 0.60 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr17_+_40458130 0.60 ENST00000587646.1
STAT5A
signal transducer and activator of transcription 5A
chr14_-_106816253 0.59 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr5_-_180076613 0.57 ENST00000261937.6
ENST00000393347.3
FLT4
fms-related tyrosine kinase 4
chr5_-_180076580 0.49 ENST00000502649.1
FLT4
fms-related tyrosine kinase 4
chr14_-_107131560 0.48 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr19_-_14530112 0.45 ENST00000592632.1
ENST00000589675.1
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr17_-_3301704 0.44 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr14_+_23016437 0.44 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr2_-_238343455 0.30 ENST00000409910.1
AC112721.2
AC112721.2
chrX_+_100805496 0.29 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr6_-_125766306 0.29 ENST00000430672.1
RP11-138M12.1
RP11-138M12.1
chr3_+_127634069 0.29 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr14_+_91709103 0.27 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr6_-_33754778 0.27 ENST00000508327.1
ENST00000513701.1
LEMD2
LEM domain containing 2
chr16_+_30662085 0.27 ENST00000569864.1
PRR14
proline rich 14
chr19_-_14529847 0.26 ENST00000590239.1
ENST00000590696.1
ENST00000591275.1
ENST00000586993.1
DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr16_+_30662050 0.24 ENST00000568754.1
PRR14
proline rich 14
chr6_-_26056695 0.23 ENST00000343677.2
HIST1H1C
histone cluster 1, H1c
chr12_-_9885888 0.22 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr19_+_18043810 0.22 ENST00000445755.2
CCDC124
coiled-coil domain containing 124
chr16_+_30662184 0.22 ENST00000300835.4
PRR14
proline rich 14
chr3_+_153202284 0.22 ENST00000446603.2
C3orf79
chromosome 3 open reading frame 79
chr19_-_10491234 0.20 ENST00000524462.1
ENST00000531836.1
ENST00000525621.1
TYK2
tyrosine kinase 2
chr4_+_75174180 0.20 ENST00000413830.1
EPGN
epithelial mitogen
chr16_+_30662360 0.20 ENST00000542965.2
PRR14
proline rich 14
chr15_-_34635314 0.17 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr20_-_33732952 0.17 ENST00000541621.1
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr19_-_50380536 0.15 ENST00000391832.3
ENST00000391834.2
ENST00000344175.5
AKT1S1
AKT1 substrate 1 (proline-rich)
chr19_-_10491130 0.15 ENST00000530829.1
ENST00000529370.1
TYK2
tyrosine kinase 2
chr2_+_232316906 0.15 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr11_+_74811578 0.14 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr11_-_117800080 0.14 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13
transmembrane protease, serine 13
chr1_-_153029980 0.13 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr22_-_30234218 0.12 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr13_+_27825706 0.11 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21
ribosomal protein L21
chr17_+_26800296 0.11 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_26800648 0.11 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr7_+_116654958 0.11 ENST00000449366.1
ST7
suppression of tumorigenicity 7
chr17_+_26800756 0.10 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_-_53686261 0.09 ENST00000294360.4
C1orf123
chromosome 1 open reading frame 123
chr14_-_20922960 0.09 ENST00000553640.1
ENST00000488532.2
OSGEP
O-sialoglycoprotein endopeptidase
chr7_-_83278322 0.08 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_-_107367951 0.08 ENST00000542196.1
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chrX_+_30261847 0.08 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr3_+_184018352 0.07 ENST00000435761.1
ENST00000439383.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr17_-_6915646 0.07 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr1_-_36107445 0.05 ENST00000373237.3
PSMB2
proteasome (prosome, macropain) subunit, beta type, 2
chr15_-_56757329 0.05 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr21_+_38792602 0.02 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr18_+_55816546 0.01 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr4_+_185570871 0.01 ENST00000512834.1
PRIMPOL
primase and polymerase (DNA-directed)
chrX_+_2924654 0.01 ENST00000381130.2
ARSH
arylsulfatase family, member H
chr1_-_160549235 0.01 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr7_-_1609591 0.00 ENST00000288607.2
ENST00000404674.3
PSMG3
proteasome (prosome, macropain) assembly chaperone 3
chr10_+_50817141 0.00 ENST00000339797.1
CHAT
choline O-acetyltransferase
chr2_-_113522248 0.00 ENST00000302450.6
CKAP2L
cytoskeleton associated protein 2-like
chr2_+_29353520 0.00 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 3.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 2.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 1.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 2.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.6 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.2 0.6 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 1.8 GO:0019864 IgG binding(GO:0019864)
0.0 1.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 2.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation