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Illumina Body Map 2, young vs old

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Results for ZNF652

Z-value: 0.59

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Transcription factors associated with ZNF652

Gene Symbol Gene ID Gene Info
ZNF652
ENSG00000198740.4 zinc finger protein 652

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF652hg19_v2_chr17_-_47439437_474395330.134.8e-01Click!

Activity profile of ZNF652 motif

Sorted Z-values of ZNF652 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_90757364 5.22 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90756769 4.35 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chrX_+_103031758 4.24 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chr17_-_10741762 3.76 ENST00000580256.2
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr2_-_220174166 3.71 ENST00000409251.3
ENST00000451506.1
ENST00000295718.2
ENST00000446182.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr11_-_130298888 3.63 ENST00000257359.6
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr6_-_34524049 3.34 ENST00000374037.3
SPDEF
SAM pointed domain containing ETS transcription factor
chr6_-_34524093 3.15 ENST00000544425.1
SPDEF
SAM pointed domain containing ETS transcription factor
chr9_+_74764340 3.12 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr16_+_56623433 3.11 ENST00000570176.1
MT3
metallothionein 3
chr10_-_10836919 2.94 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr7_-_140341251 2.92 ENST00000491728.1
DENND2A
DENN/MADD domain containing 2A
chr11_-_82444892 2.77 ENST00000329203.3
FAM181B
family with sequence similarity 181, member B
chr11_-_35547572 2.73 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr2_+_11052054 2.68 ENST00000295082.1
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr9_-_117853297 2.64 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
TNC
tenascin C
chr14_+_79746249 2.63 ENST00000428277.2
NRXN3
neurexin 3
chr19_-_51472031 2.60 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chrX_-_128788914 2.60 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr11_-_35547151 2.56 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr11_-_35547277 2.48 ENST00000527605.1
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr9_+_74764278 2.39 ENST00000238018.4
ENST00000376989.3
GDA
guanine deaminase
chr5_-_45696253 2.33 ENST00000303230.4
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr1_+_86934526 2.32 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr5_-_153857819 2.27 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr17_-_77179487 2.26 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr17_+_48610074 2.26 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr11_-_111782696 2.26 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr5_+_161494521 2.23 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chrX_-_20074895 2.23 ENST00000543767.1
MAP7D2
MAP7 domain containing 2
chr5_+_161494770 2.20 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr14_+_79745682 2.18 ENST00000557594.1
NRXN3
neurexin 3
chr14_+_79745746 2.14 ENST00000281127.7
NRXN3
neurexin 3
chr16_+_24266874 2.05 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr19_+_11649532 2.05 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1
calponin 1, basic, smooth muscle
chr11_-_111782484 2.02 ENST00000533971.1
CRYAB
crystallin, alpha B
chr17_+_47653471 1.96 ENST00000513748.1
NXPH3
neurexophilin 3
chr11_-_119293872 1.94 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chr12_+_20848377 1.90 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr8_-_110656995 1.81 ENST00000276646.9
ENST00000533065.1
SYBU
syntabulin (syntaxin-interacting)
chr14_-_22005343 1.80 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr3_+_157154578 1.79 ENST00000295927.3
PTX3
pentraxin 3, long
chr5_-_176057518 1.77 ENST00000393693.2
SNCB
synuclein, beta
chr10_-_10836865 1.76 ENST00000446372.2
SFTA1P
surfactant associated 1, pseudogene
chr12_-_120241187 1.74 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr16_-_57318566 1.73 ENST00000569059.1
ENST00000219207.5
PLLP
plasmolipin
chr3_+_183948161 1.72 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr19_-_47137942 1.70 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr17_-_46035187 1.63 ENST00000300557.2
PRR15L
proline rich 15-like
chr5_-_176057365 1.62 ENST00000310112.3
SNCB
synuclein, beta
chr7_-_140340576 1.59 ENST00000275884.6
ENST00000475837.1
DENND2A
DENN/MADD domain containing 2A
chr14_-_22005062 1.59 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr12_-_6809958 1.57 ENST00000320591.5
ENST00000534837.1
PIANP
PILR alpha associated neural protein
chr7_-_142583506 1.56 ENST00000359396.3
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr1_+_162601774 1.55 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr5_+_152870287 1.54 ENST00000340592.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr1_-_156675564 1.54 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr17_+_48610042 1.52 ENST00000503246.1
EPN3
epsin 3
chr17_+_38337491 1.52 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr4_+_81118647 1.48 ENST00000415738.2
PRDM8
PR domain containing 8
chr17_+_26800296 1.47 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_+_55795493 1.43 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr1_+_26348259 1.42 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr10_-_100995603 1.42 ENST00000370552.3
ENST00000370549.1
HPSE2
heparanase 2
chr12_+_113229962 1.40 ENST00000553114.1
ENST00000548866.1
RPH3A
rabphilin 3A homolog (mouse)
chr1_-_156647189 1.40 ENST00000368223.3
NES
nestin
chr6_+_72926145 1.38 ENST00000425662.2
ENST00000453976.2
RIMS1
regulating synaptic membrane exocytosis 1
chr19_-_51143075 1.38 ENST00000600079.1
ENST00000593901.1
SYT3
synaptotagmin III
chr17_-_45928521 1.37 ENST00000536300.1
SP6
Sp6 transcription factor
chr19_-_51142540 1.37 ENST00000598997.1
SYT3
synaptotagmin III
chr9_+_131174024 1.37 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule
chr17_-_7108436 1.36 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr5_+_152870734 1.36 ENST00000521843.2
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr3_+_120626919 1.36 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L
syntaxin binding protein 5-like
chr1_+_201708992 1.35 ENST00000367295.1
NAV1
neuron navigator 1
chr2_+_177053307 1.35 ENST00000331462.4
HOXD1
homeobox D1
chr15_+_68871569 1.35 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chr19_+_50194821 1.35 ENST00000594587.1
ENST00000595969.1
CPT1C
carnitine palmitoyltransferase 1C
chr10_-_100995540 1.34 ENST00000370546.1
ENST00000404542.1
HPSE2
heparanase 2
chr3_-_73610759 1.34 ENST00000466780.1
PDZRN3
PDZ domain containing ring finger 3
chr8_-_57233103 1.34 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr12_+_20848486 1.33 ENST00000545102.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr2_-_68547061 1.33 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chrX_-_153095813 1.32 ENST00000544474.1
PDZD4
PDZ domain containing 4
chr11_-_89224299 1.31 ENST00000343727.5
ENST00000531342.1
ENST00000375979.3
NOX4
NADPH oxidase 4
chr3_+_158991025 1.29 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr15_-_79383102 1.29 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr14_-_22005018 1.29 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr11_-_86383157 1.22 ENST00000393324.3
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr6_+_44238203 1.22 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr11_+_107461804 1.22 ENST00000531234.1
ELMOD1
ELMO/CED-12 domain containing 1
chr12_+_108523133 1.22 ENST00000547525.1
WSCD2
WSC domain containing 2
chr16_+_72459838 1.19 ENST00000564508.1
AC004158.3
AC004158.3
chr7_-_150675372 1.18 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_+_125758813 1.18 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr4_-_99578776 1.16 ENST00000515287.1
TSPAN5
tetraspanin 5
chr16_+_76311169 1.16 ENST00000307431.8
ENST00000377504.4
CNTNAP4
contactin associated protein-like 4
chr10_-_15413035 1.15 ENST00000378116.4
ENST00000455654.1
FAM171A1
family with sequence similarity 171, member A1
chr15_+_71185148 1.15 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr14_-_105420241 1.14 ENST00000557457.1
AHNAK2
AHNAK nucleoprotein 2
chr17_-_1029866 1.14 ENST00000570525.1
ABR
active BCR-related
chr12_-_6809543 1.13 ENST00000540656.1
PIANP
PILR alpha associated neural protein
chr11_-_89224139 1.11 ENST00000413594.2
NOX4
NADPH oxidase 4
chr4_-_13546632 1.11 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr17_+_26800648 1.11 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr1_-_168698433 1.11 ENST00000367817.3
DPT
dermatopontin
chr5_+_125758865 1.10 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr19_+_40973049 1.09 ENST00000598249.1
ENST00000338932.3
ENST00000344104.3
SPTBN4
spectrin, beta, non-erythrocytic 4
chr5_-_60140089 1.09 ENST00000507047.1
ENST00000438340.1
ENST00000425382.1
ENST00000508821.1
ELOVL7
ELOVL fatty acid elongase 7
chr17_+_12569306 1.08 ENST00000425538.1
MYOCD
myocardin
chr1_+_2398876 1.08 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr2_-_68547019 1.08 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr22_+_38609538 1.07 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr8_-_140715294 1.07 ENST00000303015.1
ENST00000520439.1
KCNK9
potassium channel, subfamily K, member 9
chr5_+_140201183 1.06 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5
protocadherin alpha 5
chr12_-_57443886 1.05 ENST00000300119.3
MYO1A
myosin IA
chr11_+_107461948 1.04 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chrX_-_153095945 1.03 ENST00000164640.4
PDZD4
PDZ domain containing 4
chr4_-_99578789 1.03 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr5_+_56910048 1.01 ENST00000509844.1
CTD-2023N9.3
CTD-2023N9.3
chr17_-_40333099 1.01 ENST00000607371.1
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr17_-_79139817 1.01 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr1_-_193155729 1.00 ENST00000367434.4
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr6_-_55740352 1.00 ENST00000370830.3
BMP5
bone morphogenetic protein 5
chr3_-_112360116 0.99 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr14_-_22005197 0.99 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr17_+_26800756 0.98 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_-_98235962 0.98 ENST00000513873.1
CLDND1
claudin domain containing 1
chr3_-_64431058 0.98 ENST00000564377.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr19_+_19639670 0.98 ENST00000436027.5
YJEFN3
YjeF N-terminal domain containing 3
chr2_+_115822233 0.97 ENST00000393146.2
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr12_+_6982725 0.97 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr17_-_7120525 0.97 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)
chr2_-_73511559 0.96 ENST00000521871.1
FBXO41
F-box protein 41
chr7_+_23286182 0.96 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr1_+_156611704 0.96 ENST00000329117.5
BCAN
brevican
chr11_+_19798964 0.96 ENST00000527559.2
NAV2
neuron navigator 2
chr6_-_131321863 0.95 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr11_-_89224488 0.95 ENST00000534731.1
ENST00000527626.1
NOX4
NADPH oxidase 4
chr14_+_85996507 0.94 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr4_-_114900126 0.94 ENST00000541197.1
ARSJ
arylsulfatase family, member J
chr8_-_23261589 0.93 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr12_+_31079362 0.93 ENST00000545802.1
TSPAN11
tetraspanin 11
chr1_+_24646263 0.93 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr11_-_86383370 0.93 ENST00000526834.1
ENST00000359636.2
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr11_-_128894053 0.92 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr6_-_70992888 0.91 ENST00000320755.7
COL9A1
collagen, type IX, alpha 1
chr8_-_57359131 0.90 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
PENK
proenkephalin
chr15_+_73976545 0.90 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr1_+_26485511 0.90 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr4_-_186732048 0.88 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr1_+_24645807 0.87 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_9862772 0.87 ENST00000580865.1
ENST00000583882.1
GAS7
growth arrest-specific 7
chr15_+_54903673 0.86 ENST00000560537.1
UNC13C
unc-13 homolog C (C. elegans)
chr14_-_88459503 0.86 ENST00000393568.4
ENST00000261304.2
GALC
galactosylceramidase
chr6_-_70992755 0.85 ENST00000370499.4
COL9A1
collagen, type IX, alpha 1
chr1_+_24645865 0.85 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_-_147211226 0.85 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr11_-_89224508 0.85 ENST00000525196.1
NOX4
NADPH oxidase 4
chr17_-_41985096 0.84 ENST00000269095.4
ENST00000523220.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr5_+_176057663 0.83 ENST00000318682.6
EIF4E1B
eukaryotic translation initiation factor 4E family member 1B
chr6_+_39760783 0.83 ENST00000398904.2
ENST00000538976.1
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_+_39670360 0.82 ENST00000494012.1
MACF1
microtubule-actin crosslinking factor 1
chr11_-_89223883 0.82 ENST00000528341.1
NOX4
NADPH oxidase 4
chr17_+_12569472 0.82 ENST00000343344.4
MYOCD
myocardin
chr2_-_68546530 0.81 ENST00000409559.3
CNRIP1
cannabinoid receptor interacting protein 1
chr3_-_149051444 0.81 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr17_-_19290117 0.81 ENST00000497081.2
MFAP4
microfibrillar-associated protein 4
chr19_-_9226439 0.80 ENST00000293614.1
ENST00000541538.1
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr2_-_36779411 0.79 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr2_+_204193149 0.79 ENST00000422511.2
ABI2
abl-interactor 2
chr5_+_139505520 0.79 ENST00000333305.3
IGIP
IgA-inducing protein
chr12_-_57081940 0.79 ENST00000436399.2
PTGES3
prostaglandin E synthase 3 (cytosolic)
chr10_-_97200772 0.78 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr19_+_37997812 0.78 ENST00000542455.1
ENST00000587143.1
ZNF793
zinc finger protein 793
chr11_-_118966167 0.78 ENST00000530167.1
H2AFX
H2A histone family, member X
chr1_-_203320617 0.78 ENST00000354955.4
FMOD
fibromodulin
chr4_+_144312659 0.78 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chr1_+_101185290 0.77 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
VCAM1
vascular cell adhesion molecule 1
chr7_+_47834880 0.76 ENST00000258776.4
C7orf69
chromosome 7 open reading frame 69
chr5_-_60139347 0.76 ENST00000511799.1
ELOVL7
ELOVL fatty acid elongase 7
chr6_+_126102292 0.75 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr6_+_98264571 0.74 ENST00000607823.1
RP11-436D23.1
RP11-436D23.1
chr14_+_85996471 0.74 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_24646002 0.73 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_1029052 0.73 ENST00000574437.1
ABR
active BCR-related
chr2_-_86564776 0.73 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr7_-_142583478 0.72 ENST00000436401.1
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr11_-_62752455 0.71 ENST00000360421.4
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr15_+_68871308 0.70 ENST00000261861.5
CORO2B
coronin, actin binding protein, 2B
chr17_+_44076616 0.70 ENST00000537309.1
STH
saitohin
chr14_+_38033252 0.69 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr8_+_28351707 0.68 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3
frizzled family receptor 3
chr2_-_190044480 0.68 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_+_25200074 0.67 ENST00000390687.4
ENST00000584968.1
ENST00000346403.6
ENST00000554227.2
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr1_+_24645915 0.67 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr11_-_62752429 0.67 ENST00000377871.3
SLC22A6
solute carrier family 22 (organic anion transporter), member 6
chr18_+_32621324 0.67 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr16_-_75284758 0.67 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chr3_+_113616317 0.67 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF652

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.6 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
1.8 5.5 GO:0006147 guanine catabolic process(GO:0006147)
1.0 3.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.9 3.7 GO:1990502 dense core granule maturation(GO:1990502)
0.9 6.5 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.9 2.6 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.8 2.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.7 2.0 GO:0097254 renal tubular secretion(GO:0097254)
0.5 2.6 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.5 1.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.5 1.9 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.4 1.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.4 3.5 GO:2000821 regulation of grooming behavior(GO:2000821)
0.4 1.4 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.3 0.7 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.3 1.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.3 6.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 3.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 2.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 1.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 2.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 1.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 1.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 0.9 GO:0018277 protein deamination(GO:0018277)
0.2 2.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 3.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.7 GO:0019236 response to pheromone(GO:0019236)
0.2 4.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 4.4 GO:0071420 cellular response to histamine(GO:0071420)
0.2 11.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 0.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 2.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 4.1 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 2.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.9 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1 3.8 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 1.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 1.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.8 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 1.1 GO:0097338 response to clozapine(GO:0097338)
0.1 2.6 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.6 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 1.0 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0035617 stress granule disassembly(GO:0035617)
0.1 1.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:1904238 mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) pericyte cell differentiation(GO:1904238)
0.1 1.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 2.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.9 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.1 3.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.4 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 4.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.1 3.4 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.6 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.3 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 1.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 1.4 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.8 GO:0015866 ADP transport(GO:0015866)
0.0 1.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.0 1.2 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 1.1 GO:0007567 parturition(GO:0007567)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 4.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 1.1 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372) membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 1.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.1 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 1.8 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 1.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 1.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.5 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 1.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.8 GO:0046710 GDP metabolic process(GO:0046710)
0.0 2.9 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 2.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 1.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.0 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.4 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 2.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0072716 response to actinomycin D(GO:0072716)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.5 GO:0090662 ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 2.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.8 2.3 GO:0098855 HCN channel complex(GO:0098855)
0.5 2.9 GO:0044308 axonal spine(GO:0044308)
0.3 1.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 6.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 0.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 4.3 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 2.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.3 GO:0043259 laminin-10 complex(GO:0043259)
0.2 9.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 2.0 GO:0070852 cell body fiber(GO:0070852)
0.2 0.5 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.1 7.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 4.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0097447 dendritic tree(GO:0097447)
0.1 5.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0071953 elastic fiber(GO:0071953)
0.1 1.1 GO:0044305 calyx of Held(GO:0044305)
0.1 1.8 GO:0097433 dense body(GO:0097433)
0.1 3.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.8 GO:0043194 axon initial segment(GO:0043194)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.0 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 1.7 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0031672 A band(GO:0031672)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 4.9 GO:0034705 potassium channel complex(GO:0034705)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 19.2 GO:0098793 presynapse(GO:0098793)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 3.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.1 GO:0043209 myelin sheath(GO:0043209)
0.0 3.1 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.9 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0033643 host cell part(GO:0033643)
0.0 10.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.4 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 2.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 2.8 GO:0015629 actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.8 5.5 GO:0008892 guanine deaminase activity(GO:0008892)
1.2 3.6 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.9 3.8 GO:1990175 EH domain binding(GO:1990175)
0.7 2.8 GO:0030305 heparanase activity(GO:0030305)
0.6 2.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.5 6.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.5 1.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.5 2.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 3.6 GO:0045545 syndecan binding(GO:0045545)
0.4 6.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.4 3.4 GO:1903136 cuprous ion binding(GO:1903136)
0.4 2.5 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 3.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 1.0 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.3 3.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 6.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 4.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 2.9 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 1.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 3.1 GO:0046870 cadmium ion binding(GO:0046870)
0.2 1.8 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 1.9 GO:0034235 GPI anchor binding(GO:0034235)
0.2 1.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 0.7 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 1.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.9 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 2.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.6 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.6 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 3.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 6.8 GO:0030507 spectrin binding(GO:0030507)
0.1 1.9 GO:0008430 selenium binding(GO:0008430) phosphate ion binding(GO:0042301)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.5 GO:0016918 retinal binding(GO:0016918)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 6.0 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 1.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.7 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.3 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.1 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095) GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 12.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 8.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 6.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 11.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 3.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 4.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 9.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 4.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 2.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 2.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 3.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins