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Illumina Body Map 2, young vs old

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Results for ZNF691

Z-value: 0.14

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Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ENSG00000164011.13 zinc finger protein 691

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF691hg19_v2_chr1_+_43312258_433123100.134.8e-01Click!

Activity profile of ZNF691 motif

Sorted Z-values of ZNF691 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_26644441 4.49 ENST00000374213.2
CD52 molecule
chr22_+_23222886 3.18 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr11_+_60223312 3.15 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
membrane-spanning 4-domains, subfamily A, member 1
chr3_+_46412345 3.07 ENST00000292303.4
chemokine (C-C motif) receptor 5 (gene/pseudogene)
chr11_+_60223225 2.88 ENST00000524807.1
ENST00000345732.4
membrane-spanning 4-domains, subfamily A, member 1
chr15_-_74726283 2.87 ENST00000543145.2
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr22_+_23264766 2.67 ENST00000390331.2
immunoglobulin lambda constant 7
chr19_-_17932314 2.48 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
insulin-like 3 (Leydig cell)
chr17_-_61777459 2.30 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr14_-_106725723 2.20 ENST00000390609.2
immunoglobulin heavy variable 3-23
chr17_+_72595971 2.15 ENST00000581412.1
CTD-2006K23.1
chr1_+_26856236 2.03 ENST00000374168.2
ENST00000374166.4
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_120502441 1.86 ENST00000446727.2
coiled-coil domain containing 64
chr12_-_51718436 1.82 ENST00000544402.1
bridging integrator 2
chr12_-_51717875 1.77 ENST00000604560.1
bridging integrator 2
chr17_-_73840614 1.65 ENST00000586108.1
unc-13 homolog D (C. elegans)
chr12_-_51717948 1.64 ENST00000267012.4
bridging integrator 2
chr1_+_203734296 1.64 ENST00000442561.2
ENST00000367217.5
lymphocyte transmembrane adaptor 1
chr4_+_657485 1.57 ENST00000471824.2
phosphodiesterase 6B, cGMP-specific, rod, beta
chr12_-_51717922 1.56 ENST00000452142.2
bridging integrator 2
chr1_+_28199047 1.49 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
thymocyte selection associated family member 2
chr8_+_27168988 1.40 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
protein tyrosine kinase 2 beta
chr2_+_202098203 1.37 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
caspase 8, apoptosis-related cysteine peptidase
chr7_+_142494920 1.35 ENST00000390418.1
T cell receptor beta joining 2-6
chr5_-_131347501 1.32 ENST00000543479.1
acyl-CoA synthetase long-chain family member 6
chr9_-_135754164 1.29 ENST00000298545.3
adenylate kinase 8
chr8_+_27169138 1.27 ENST00000522338.1
protein tyrosine kinase 2 beta
chr4_+_96761238 1.26 ENST00000295266.4
pyruvate dehydrogenase (lipoamide) alpha 2
chrX_-_153775760 1.25 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
glucose-6-phosphate dehydrogenase
chrX_-_153775426 1.24 ENST00000393562.2
glucose-6-phosphate dehydrogenase
chr15_-_40398812 1.23 ENST00000561360.1
Bcl2 modifying factor
chr14_+_22970526 1.23 ENST00000390498.1
T cell receptor alpha joining 39
chr3_-_107596910 1.22 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
long intergenic non-protein coding RNA 635
chr17_-_73839792 1.21 ENST00000590762.1
unc-13 homolog D (C. elegans)
chr22_+_22569155 1.17 ENST00000390287.2
immunoglobulin lambda variable 10-54
chr17_-_73840415 1.14 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
unc-13 homolog D (C. elegans)
chr15_-_26108355 1.14 ENST00000356865.6
ATPase, class V, type 10A
chr1_-_183622442 1.09 ENST00000308641.4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr5_-_131347583 1.09 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
acyl-CoA synthetase long-chain family member 6
chr2_-_85895295 1.08 ENST00000428225.1
ENST00000519937.2
surfactant protein B
chr16_+_57662419 1.06 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr2_+_202098166 1.04 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
caspase 8, apoptosis-related cysteine peptidase
chr17_+_73606766 1.03 ENST00000578462.1
myosin XVB pseudogene
chrX_+_102965835 1.00 ENST00000319560.6
transmembrane protein 31
chrX_-_153775047 0.99 ENST00000433845.1
ENST00000439227.1
glucose-6-phosphate dehydrogenase
chr2_+_68961934 0.98 ENST00000409202.3
Rho GTPase activating protein 25
chr9_+_135854091 0.96 ENST00000450530.1
ENST00000534944.1
growth factor independent 1B transcription repressor
chr17_+_79495397 0.96 ENST00000417245.2
ENST00000334850.7
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr5_+_96840389 0.95 ENST00000504012.1
RP11-1E3.1
chr16_+_810728 0.93 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
mesothelin
chr2_+_68961905 0.93 ENST00000295381.3
Rho GTPase activating protein 25
chr16_-_11492366 0.93 ENST00000595360.1
Protein LOC388210
chr1_+_178482212 0.92 ENST00000319416.2
ENST00000258298.2
ENST00000367643.3
ENST00000367642.3
testis expressed 35
chr6_+_31553901 0.92 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr6_+_31553978 0.91 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr14_+_22971215 0.91 ENST00000390499.1
T cell receptor alpha joining 38
chr22_-_32058416 0.90 ENST00000439502.2
phosphatidylserine decarboxylase
chr20_-_45976816 0.88 ENST00000441977.1
zinc finger, MYND-type containing 8
chr11_+_102188272 0.88 ENST00000532808.1
baculoviral IAP repeat containing 3
chr5_-_179107975 0.79 ENST00000376974.4
chibby homolog 3 (Drosophila)
chr2_+_68962014 0.77 ENST00000467265.1
Rho GTPase activating protein 25
chr11_+_121461097 0.77 ENST00000527934.1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_202125219 0.76 ENST00000323492.7
caspase 8, apoptosis-related cysteine peptidase
chr3_+_129693523 0.76 ENST00000507066.1
thyrotropin-releasing hormone
chr15_+_89402148 0.73 ENST00000560601.1
aggrecan
chr9_+_84603687 0.72 ENST00000344803.2
SPATA31 subfamily D, member 1
chr1_+_223354486 0.72 ENST00000446145.1
RP11-239E10.3
chr12_-_10605929 0.72 ENST00000347831.5
ENST00000359151.3
killer cell lectin-like receptor subfamily C, member 1
chr5_-_179045199 0.70 ENST00000523921.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr4_-_120243545 0.70 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr17_+_37026106 0.67 ENST00000318008.6
LIM and SH3 protein 1
chr16_+_57662138 0.65 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr17_+_43922241 0.64 ENST00000329196.5
signal peptide peptidase like 2C
chr17_-_41738931 0.64 ENST00000329168.3
ENST00000549132.1
mesenchyme homeobox 1
chr10_-_4720301 0.63 ENST00000449712.1
long intergenic non-protein coding RNA 704
chrX_-_62571187 0.62 ENST00000335144.3
spindlin family, member 4
chr11_-_36619771 0.61 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
recombination activating gene 2
chr1_-_233431458 0.61 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr1_-_205180664 0.61 ENST00000367161.3
ENST00000367162.3
ENST00000367160.4
dual serine/threonine and tyrosine protein kinase
chr17_+_37026284 0.61 ENST00000433206.2
ENST00000435347.3
LIM and SH3 protein 1
chr19_+_35330037 0.60 ENST00000601776.1
CTC-523E23.5
chr1_-_111174054 0.58 ENST00000369770.3
potassium voltage-gated channel, shaker-related subfamily, member 2
chr1_-_203144941 0.58 ENST00000255416.4
myosin binding protein H
chr4_-_40516560 0.57 ENST00000513473.1
RNA binding motif protein 47
chr6_-_144329531 0.56 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
pleiomorphic adenoma gene-like 1
chr8_+_32579321 0.55 ENST00000522402.1
neuregulin 1
chr3_-_194968576 0.55 ENST00000429994.1
xyloside xylosyltransferase 1
chr16_-_53737795 0.55 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1-like
chr4_-_83719983 0.54 ENST00000319540.4
stearoyl-CoA desaturase 5
chr14_-_92333873 0.53 ENST00000435962.2
tandem C2 domains, nuclear
chr3_+_44596679 0.51 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
zinc finger with KRAB and SCAN domains 7
chr11_-_133826852 0.49 ENST00000533871.2
ENST00000321016.8
immunoglobulin superfamily, member 9B
chr8_+_62737875 0.48 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
chr5_-_131892501 0.47 ENST00000450655.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr6_+_31021973 0.47 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HLA complex group 22
chr11_-_116371347 0.46 ENST00000452629.1
AP001891.1
chr11_-_76367756 0.44 ENST00000531511.1
RP11-672A2.4
chr1_+_248201474 0.43 ENST00000366479.2
olfactory receptor, family 2, subfamily L, member 2
chr4_+_48492269 0.43 ENST00000327939.4
zygote arrest 1
chr5_+_53686658 0.43 ENST00000512618.1
long intergenic non-protein coding RNA 1033
chr6_-_159240415 0.43 ENST00000367075.3
ezrin
chr3_-_167452298 0.42 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
programmed cell death 10
chr11_+_5410607 0.42 ENST00000328611.3
olfactory receptor, family 51, subfamily M, member 1
chr22_-_32058166 0.40 ENST00000435900.1
ENST00000336566.4
phosphatidylserine decarboxylase
chr9_+_99691286 0.39 ENST00000372322.3
NUT family member 2G
chr17_-_3417062 0.39 ENST00000570318.1
ENST00000541913.1
spermatogenesis associated 22
chr7_-_84569561 0.36 ENST00000439105.1
AC074183.4
chr6_+_28493666 0.36 ENST00000412168.2
glutathione peroxidase 5 (epididymal androgen-related protein)
chr1_-_33647267 0.35 ENST00000291416.5
tripartite motif containing 62
chr11_-_6008215 0.35 ENST00000332249.4
olfactory receptor, family 52, subfamily L, member 1
chr19_-_9649253 0.34 ENST00000593003.1
zinc finger protein 426
chr6_+_31021225 0.33 ENST00000565192.1
ENST00000562344.1
HLA complex group 22
chr17_+_75401152 0.33 ENST00000585930.1
septin 9
chr20_+_62585007 0.31 ENST00000595604.1
Uncharacterized protein
chr7_-_155326532 0.30 ENST00000406197.1
ENST00000321736.5
canopy FGF signaling regulator 1
chr22_-_24126145 0.30 ENST00000598975.1
Uncharacterized protein
chr8_+_32579341 0.30 ENST00000519240.1
ENST00000539990.1
neuregulin 1
chr16_-_53737722 0.30 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1-like
chr19_-_9649303 0.30 ENST00000253115.2
zinc finger protein 426
chr5_-_39074479 0.29 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RPTOR independent companion of MTOR, complex 2
chr1_-_16763911 0.28 ENST00000375577.1
ENST00000335496.1
spermatogenesis associated 21
chr2_+_3800169 0.28 ENST00000399143.3
doublecortin domain containing 2C
chr5_+_3596168 0.26 ENST00000302006.3
iroquois homeobox 1
chr17_+_80416482 0.25 ENST00000309794.11
ENST00000345415.7
ENST00000457415.3
ENST00000584411.1
ENST00000412079.2
ENST00000577432.1
nuclear prelamin A recognition factor
chr6_+_28493753 0.23 ENST00000469384.1
glutathione peroxidase 5 (epididymal androgen-related protein)
chr3_+_9850199 0.23 ENST00000452597.1
tubulin tyrosine ligase-like family, member 3
chr14_+_22997487 0.23 ENST00000390521.1
T cell receptor alpha joining 16
chr9_+_139690784 0.22 ENST00000338005.6
coiled-coil domain containing 183
chr2_+_106468204 0.21 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr10_-_91011548 0.21 ENST00000456827.1
lipase A, lysosomal acid, cholesterol esterase
chr8_-_144679532 0.19 ENST00000534380.1
ENST00000533494.1
ENST00000531218.1
ENST00000526340.1
ENST00000533204.1
ENST00000532400.1
ENST00000529516.1
ENST00000534377.1
ENST00000531621.1
ENST00000530191.1
ENST00000524900.1
ENST00000526838.1
ENST00000531931.1
ENST00000534475.1
ENST00000442189.2
ENST00000524624.1
ENST00000532596.1
ENST00000529832.1
ENST00000530306.1
ENST00000530545.1
ENST00000525261.1
ENST00000534804.1
ENST00000528303.1
ENST00000528610.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr8_-_144679602 0.18 ENST00000526710.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr8_-_144679264 0.17 ENST00000531953.1
ENST00000526133.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrX_+_102469997 0.17 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr8_-_144679296 0.16 ENST00000317198.6
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_-_1821496 0.16 ENST00000564628.1
ENST00000563498.1
NME/NM23 nucleoside diphosphate kinase 3
chr3_-_167452262 0.16 ENST00000487947.2
programmed cell death 10
chr8_-_20831355 0.15 ENST00000518967.1
RP11-369E15.3
chr9_+_135754263 0.15 ENST00000356311.5
ENST00000350499.6
chromosome 9 open reading frame 9
chr11_-_57148619 0.15 ENST00000287143.2
proteoglycan 3
chrX_+_153775821 0.14 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_+_44748361 0.13 ENST00000533202.1
ENST00000533080.1
ENST00000520358.2
ENST00000520999.2
tetraspanin 18
chr13_-_52703187 0.13 ENST00000355568.4
NIMA-related kinase 5
chr10_+_4828815 0.13 ENST00000533295.1
aldo-keto reductase family 1, member E2
chr6_-_27279949 0.12 ENST00000444565.1
ENST00000377451.2
POM121 transmembrane nucleoporin-like 2
chr3_-_157251383 0.11 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
ventricular zone expressed PH domain-containing 1
chr17_+_80416050 0.10 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
nuclear prelamin A recognition factor
chr1_-_148202536 0.09 ENST00000544708.1
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr10_-_99258135 0.09 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr1_+_178482262 0.08 ENST00000367641.3
ENST00000367639.1
testis expressed 35
chr11_-_5323226 0.07 ENST00000380224.1
olfactory receptor, family 51, subfamily B, member 4
chr6_+_151186554 0.07 ENST00000367321.3
ENST00000367307.4
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr17_+_80416609 0.07 ENST00000577410.1
nuclear prelamin A recognition factor
chr1_+_33938236 0.06 ENST00000361328.3
ENST00000373413.2
zinc finger and SCAN domain containing 20
chr6_-_90529418 0.06 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1, midasin homolog (yeast)
chr19_+_9434841 0.05 ENST00000446085.4
ENST00000603656.1
ENST00000541595.2
ENST00000592504.1
ENST00000585352.1
ENST00000317221.7
ENST00000586255.1
ENST00000592896.1
ENST00000605750.1
ENST00000603380.1
ENST00000538743.1
ENST00000589208.1
ENST00000592298.1
ENST00000585377.1
ENST00000393883.2
ENST00000588124.1
ENST00000602738.1
ZNF559-ZNF177 readthrough
zinc finger protein 559
zinc finger protein 177
chr2_-_203736452 0.04 ENST00000419460.1
islet cell autoantigen 1,69kDa-like
chr20_+_62887139 0.03 ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr5_+_179078298 0.03 ENST00000418535.2
ENST00000425471.1
Uncharacterized protein
chr10_+_104678032 0.03 ENST00000369878.4
ENST00000369875.3
cyclin M2
chr2_-_863877 0.03 ENST00000415700.1
long intergenic non-protein coding RNA 1115
chr11_+_327171 0.02 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr17_-_38821373 0.02 ENST00000394052.3
keratin 222
chr10_-_5638048 0.02 ENST00000478294.1
RP13-463N16.6
chr20_-_33735070 0.01 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
ER degradation enhancer, mannosidase alpha-like 2
chr2_+_238475217 0.01 ENST00000165524.1
prolactin releasing hormone
chr12_-_109221160 0.01 ENST00000326470.5
slingshot protein phosphatase 1
chr18_+_74240610 0.01 ENST00000578092.1
ENST00000578613.1
ENST00000583578.1
long intergenic non-protein coding RNA 908
chr3_+_183899770 0.00 ENST00000442686.1
adaptor-related protein complex 2, mu 1 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0002432 granuloma formation(GO:0002432)
0.6 3.2 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.6 3.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 2.7 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3 3.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.3 0.8 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 6.8 GO:0097320 membrane tubulation(GO:0097320)
0.2 2.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.8 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.2 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.5 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.9 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 4.5 GO:0045730 respiratory burst(GO:0045730)
0.1 0.6 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.1 2.9 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.6 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.6 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.9 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 4.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.9 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 1.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 2.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 1.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 6.0 GO:0042100 B cell proliferation(GO:0042100)
0.0 2.1 GO:0021591 ventricular system development(GO:0021591)
0.0 1.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 3.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 2.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 1.8 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 6.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 3.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 1.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 4.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.1 GO:0097486 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0033010 paranodal junction(GO:0033010)
0.0 12.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 3.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 2.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 1.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 1.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.2 1.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 3.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 6.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.5 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 4.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 2.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 4.3 GO:0003823 antigen binding(GO:0003823)
0.0 1.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 2.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 3.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 3.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors