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Illumina Body Map 2, young vs old

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Results for ZSCAN4

Z-value: 0.95

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Transcription factors associated with ZSCAN4

Gene Symbol Gene ID Gene Info
ENSG00000180532.6 zinc finger and SCAN domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZSCAN4hg19_v2_chr19_+_58180303_58180303-0.144.5e-01Click!

Activity profile of ZSCAN4 motif

Sorted Z-values of ZSCAN4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_47613673 2.93 ENST00000594486.1
Protein LOC101060037
chr3_+_111393501 2.38 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_111393659 2.34 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr1_+_233765353 2.22 ENST00000366620.1
potassium channel, subfamily K, member 1
chr16_-_86542652 2.13 ENST00000599749.1
FOXF1 adjacent non-coding developmental regulatory RNA
chr9_-_93727673 2.04 ENST00000427745.1
RP11-367F23.1
chrX_-_20134990 1.97 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7 domain containing 2
chr17_+_63133587 1.91 ENST00000449996.3
ENST00000262406.9
regulator of G-protein signaling 9
chr8_+_85095013 1.87 ENST00000522613.1
RALY RNA binding protein-like
chr17_+_9728828 1.85 ENST00000262441.5
glucagon-like peptide 2 receptor
chr12_-_16762802 1.82 ENST00000534946.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_16762971 1.79 ENST00000540590.1
LIM domain only 3 (rhombotin-like 2)
chr16_-_86542455 1.77 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FOXF1 adjacent non-coding developmental regulatory RNA
chr17_+_2699697 1.77 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1 GTPase activating protein 2
chr4_-_168155730 1.75 ENST00000502330.1
ENST00000357154.3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_56385290 1.69 ENST00000564727.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr7_-_30008849 1.61 ENST00000409497.1
secernin 1
chr16_+_86229728 1.58 ENST00000601250.1
long intergenic non-protein coding RNA 1082
chrX_-_20134713 1.53 ENST00000452324.3
MAP7 domain containing 2
chr1_+_2036149 1.52 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
protein kinase C, zeta
chr1_-_177133818 1.46 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr19_+_30863271 1.44 ENST00000355537.3
zinc finger protein 536
chr17_-_46799872 1.43 ENST00000290294.3
prostate cancer susceptibility candidate 1
chr5_-_82969405 1.41 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr8_+_85095497 1.39 ENST00000522455.1
ENST00000521695.1
RALY RNA binding protein-like
chr19_+_7660716 1.37 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr15_+_78632666 1.34 ENST00000299529.6
cellular retinoic acid binding protein 1
chr15_+_40643227 1.31 ENST00000448599.2
proline/histidine/glycine-rich 1
chr9_+_125137565 1.29 ENST00000373698.5
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_+_41086215 1.26 ENST00000547702.1
ENST00000551424.1
contactin 1
chr1_-_161600990 1.26 ENST00000531221.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr4_-_89619386 1.20 ENST00000323061.5
nucleosome assembly protein 1-like 5
chr4_-_168155700 1.19 ENST00000357545.4
ENST00000512648.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_+_23847267 1.16 ENST00000321728.7
protein kinase C, beta
chr8_+_85095769 1.10 ENST00000518566.1
RALY RNA binding protein-like
chr19_-_38714847 1.08 ENST00000420980.2
ENST00000355526.4
D4, zinc and double PHD fingers family 1
chr4_-_168155577 1.08 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr4_-_168155169 1.06 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_161600942 1.05 ENST00000421702.2
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr8_-_134114887 1.05 ENST00000519341.1
Src-like-adaptor
chr1_-_21978312 1.04 ENST00000359708.4
ENST00000290101.4
RAP1 GTPase activating protein
chr4_-_168155417 1.02 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_-_134114721 1.01 ENST00000522119.1
ENST00000523610.1
ENST00000521302.1
ENST00000519558.1
ENST00000519747.1
ENST00000517648.1
Src-like-adaptor
chr5_-_82969363 0.96 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr1_-_161600822 0.95 ENST00000534776.1
ENST00000540048.1
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_+_126262027 0.94 ENST00000526311.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr4_-_168155300 0.93 ENST00000541637.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_161519682 0.93 ENST00000367969.3
ENST00000443193.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr20_-_21494654 0.92 ENST00000377142.4
NK2 homeobox 2
chr18_-_31603603 0.91 ENST00000586553.1
nucleolar protein 4
chr16_+_15737124 0.89 ENST00000396355.1
ENST00000396353.2
nudE neurodevelopment protein 1
chr1_-_161519579 0.86 ENST00000426740.1
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr11_+_61717535 0.84 ENST00000534553.1
ENST00000301774.9
bestrophin 1
chr10_+_18549645 0.82 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr5_+_152870287 0.82 ENST00000340592.5
glutamate receptor, ionotropic, AMPA 1
chr3_-_195538728 0.82 ENST00000349607.4
ENST00000346145.4
mucin 4, cell surface associated
chr1_-_153588765 0.81 ENST00000368701.1
ENST00000344616.2
S100 calcium binding protein A14
chr8_-_134115118 0.80 ENST00000395352.3
ENST00000338087.5
Src-like-adaptor
chr12_-_81331697 0.75 ENST00000552864.1
lin-7 homolog A (C. elegans)
chr2_-_98972468 0.72 ENST00000454230.1
Uncharacterized protein
chr3_-_58572760 0.70 ENST00000447756.2
family with sequence similarity 107, member A
chr21_+_45879814 0.67 ENST00000596691.1
LRRC3 downstream neighbor (non-protein coding)
chr8_+_26247878 0.67 ENST00000518611.1
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_-_184006611 0.66 ENST00000546159.1
collagen beta(1-O)galactosyltransferase 2
chr1_+_159141397 0.63 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
cell adhesion molecule 3
chr2_+_234545092 0.63 ENST00000344644.5
UDP glucuronosyltransferase 1 family, polypeptide A10
chr9_+_103790991 0.63 ENST00000374874.3
Lipid phosphate phosphatase-related protein type 1
chr8_-_134114866 0.62 ENST00000524345.1
Src-like-adaptor
chr3_-_195538760 0.61 ENST00000475231.1
mucin 4, cell surface associated
chr11_+_34643600 0.60 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr19_-_46999755 0.60 ENST00000599531.1
paraneoplastic Ma antigen family-like 2
chr14_-_94254821 0.60 ENST00000393140.1
proline rich membrane anchor 1
chr1_-_154580616 0.59 ENST00000368474.4
adenosine deaminase, RNA-specific
chr18_+_32402321 0.58 ENST00000587723.1
dystrobrevin, alpha
chr6_-_34113856 0.57 ENST00000538487.2
glutamate receptor, metabotropic 4
chr19_-_9649253 0.57 ENST00000593003.1
zinc finger protein 426
chr8_+_85095553 0.57 ENST00000521268.1
RALY RNA binding protein-like
chr7_-_50633078 0.56 ENST00000444124.2
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_-_78400364 0.55 ENST00000535697.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_71679350 0.54 ENST00000553621.1
RP6-91H8.1
chr3_-_53290016 0.53 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
transketolase
chr3_+_197185270 0.52 ENST00000420213.1
AC128709.2
chr12_-_81331460 0.52 ENST00000549417.1
lin-7 homolog A (C. elegans)
chr10_+_43932553 0.51 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
zinc finger protein 487
chr11_+_61717816 0.50 ENST00000435278.2
bestrophin 1
chr9_-_20621834 0.49 ENST00000429426.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_173724771 0.46 ENST00000538974.1
ENST00000540783.1
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_41909561 0.46 ENST00000372991.4
cyclin D3
chr15_-_37392724 0.46 ENST00000424352.2
Meis homeobox 2
chr12_-_54694807 0.46 ENST00000435572.2
nuclear factor, erythroid 2
chr6_-_41909466 0.44 ENST00000414200.2
cyclin D3
chr2_-_175462934 0.43 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr19_+_49927006 0.43 ENST00000576655.1
golgi-associated, olfactory signaling regulator
chr9_-_107361788 0.43 ENST00000374779.2
olfactory receptor, family 13, subfamily C, member 5
chr8_-_72987810 0.42 ENST00000262209.4
transient receptor potential cation channel, subfamily A, member 1
chr1_+_226736446 0.41 ENST00000366788.3
ENST00000366789.4
chromosome 1 open reading frame 95
chr5_+_176784837 0.41 ENST00000408923.3
regulator of G-protein signaling 14
chr3_+_130569592 0.41 ENST00000533801.2
ATPase, Ca++ transporting, type 2C, member 1
chr19_-_3801789 0.41 ENST00000590849.1
ENST00000395045.2
megakaryocyte-associated tyrosine kinase
chr15_-_37392703 0.40 ENST00000382766.2
ENST00000444725.1
Meis homeobox 2
chr17_+_30348024 0.40 ENST00000327564.7
ENST00000584368.1
ENST00000394713.3
ENST00000341671.7
leucine rich repeat containing 37B
chr11_-_62783276 0.39 ENST00000535878.1
ENST00000545207.1
solute carrier family 22 (organic anion transporter), member 8
chr9_+_128510454 0.39 ENST00000491787.3
ENST00000447726.2
pre-B-cell leukemia homeobox 3
chr10_-_62332357 0.36 ENST00000503366.1
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_90272339 0.36 ENST00000522779.1
ankyrin repeat domain 6
chr19_+_49436936 0.35 ENST00000221403.2
ENST00000523250.1
ENST00000522614.1
dihydrodiol dehydrogenase (dimeric)
chr4_-_103682071 0.34 ENST00000505239.1
mannosidase, beta A, lysosomal
chr2_-_101034070 0.34 ENST00000264249.3
carbohydrate sulfotransferase 10
chr12_+_10163231 0.33 ENST00000396502.1
ENST00000338896.5
C-type lectin domain family 12, member B
chr2_-_160473114 0.33 ENST00000392783.2
bromodomain adjacent to zinc finger domain, 2B
chr4_-_103682145 0.33 ENST00000226578.4
mannosidase, beta A, lysosomal
chrX_+_17393543 0.33 ENST00000380060.3
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr17_+_72462525 0.32 ENST00000360141.3
CD300a molecule
chrX_-_62571187 0.31 ENST00000335144.3
spindlin family, member 4
chr1_+_104615595 0.31 ENST00000418362.1
RP11-364B6.1
chr3_+_50284321 0.31 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr15_+_75575176 0.30 ENST00000434739.3
golgin A6 family, member D
chr9_-_114090713 0.30 ENST00000302681.1
ENST00000374428.1
olfactory receptor, family 2, subfamily K, member 2
chr7_-_10979750 0.30 ENST00000339600.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr11_-_1619524 0.30 ENST00000412090.1
keratin associated protein 5-2
chr17_-_56405407 0.29 ENST00000343736.4
benzodiazepine receptor (peripheral) associated protein 1
chr19_-_40596828 0.29 ENST00000414720.2
ENST00000455521.1
ENST00000340963.5
ENST00000595773.1
zinc finger protein 780A
chr12_+_133613878 0.29 ENST00000392319.2
ENST00000543758.1
zinc finger protein 84
chr10_+_88414338 0.28 ENST00000241891.5
ENST00000443292.1
opsin 4
chrX_-_62571220 0.28 ENST00000374884.2
spindlin family, member 4
chr12_-_96390063 0.28 ENST00000541929.1
histidine ammonia-lyase
chr11_-_75062730 0.28 ENST00000420843.2
ENST00000360025.3
arrestin, beta 1
chrX_+_2984874 0.27 ENST00000359361.2
arylsulfatase F
chr2_+_240323439 0.26 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr15_+_75550940 0.26 ENST00000300576.5
golgin A6 family, member C
chr17_-_56406117 0.26 ENST00000268893.6
ENST00000355701.3
benzodiazepine receptor (peripheral) associated protein 1
chr16_+_29690358 0.25 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr8_+_107593198 0.24 ENST00000517686.1
oxidation resistance 1
chr21_+_25801088 0.24 ENST00000415182.1
AP000476.1
chr4_+_15779901 0.24 ENST00000226279.3
CD38 molecule
chr19_-_40596767 0.23 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
zinc finger protein 780A
chr7_-_84816122 0.23 ENST00000444867.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr15_+_72947079 0.23 ENST00000421285.3
golgin A6 family, member B
chr17_-_67057203 0.22 ENST00000340001.4
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_+_88414298 0.22 ENST00000372071.2
opsin 4
chr6_+_29795595 0.22 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
major histocompatibility complex, class I, G
chr12_-_96390108 0.22 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr21_+_25801041 0.21 ENST00000453784.2
ENST00000423581.1
AP000476.1
chr1_+_169337412 0.21 ENST00000426663.1
basic leucine zipper nuclear factor 1
chr19_+_44716768 0.21 ENST00000586048.1
zinc finger protein 227
chr22_+_39853258 0.20 ENST00000341184.6
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr2_-_27603582 0.20 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr4_-_186578674 0.19 ENST00000438278.1
sorbin and SH3 domain containing 2
chr11_+_120039685 0.18 ENST00000530303.1
ENST00000319763.1
Uncharacterized protein
chr5_+_61602055 0.18 ENST00000381103.2
kinesin heavy chain member 2A
chr17_-_34207295 0.18 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr1_+_94883931 0.17 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ATP-binding cassette, sub-family D (ALD), member 3
chr1_-_228603694 0.17 ENST00000366697.2
tripartite motif containing 17
chr3_+_98482175 0.16 ENST00000485391.1
ENST00000492254.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr14_+_89290965 0.16 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr2_-_214016314 0.16 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr13_-_79980315 0.16 ENST00000438737.2
RNA binding motif protein 26
chr8_+_107670064 0.16 ENST00000312046.6
oxidation resistance 1
chr12_+_129028500 0.16 ENST00000315208.8
transmembrane protein 132C
chr19_-_40562063 0.15 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
zinc finger protein 780B
chr1_+_39670423 0.15 ENST00000536367.1
microtubule-actin crosslinking factor 1
chr10_-_105238997 0.15 ENST00000369783.4
calcium homeostasis modulator 3
chr11_+_111750206 0.15 ENST00000530214.1
ENST00000530799.1
chromosome 11 open reading frame 1
chr16_-_55909211 0.14 ENST00000520435.1
carboxylesterase 5A
chr8_-_16050142 0.14 ENST00000536385.1
ENST00000381998.4
macrophage scavenger receptor 1
chr4_+_74718906 0.13 ENST00000226524.3
platelet factor 4 variant 1
chr9_+_128509624 0.13 ENST00000342287.5
ENST00000373487.4
pre-B-cell leukemia homeobox 3
chr14_+_23654525 0.13 ENST00000399910.1
ENST00000492621.1
chromosome 14 open reading frame 164
chr1_-_110283138 0.12 ENST00000256594.3
glutathione S-transferase mu 3 (brain)
chr19_+_571277 0.12 ENST00000346916.4
ENST00000545507.2
basigin (Ok blood group)
chr7_-_99063769 0.12 ENST00000394186.3
ENST00000359832.4
ENST00000449683.1
ENST00000488775.1
ENST00000523680.1
ENST00000292475.3
ENST00000430982.1
ENST00000555673.1
ENST00000413834.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
pentatricopeptide repeat domain 1
ATP5J2-PTCD1 readthrough
chr11_-_128812744 0.12 ENST00000458238.2
ENST00000531399.1
ENST00000602346.1
tumor protein p53 regulated apoptosis inducing protein 1
chr21_-_33651324 0.12 ENST00000290130.3
MIS18 kinetochore protein A
chr14_-_48143999 0.11 ENST00000439988.3
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chrX_+_1387721 0.11 ENST00000419094.1
ENST00000381509.3
ENST00000494969.2
ENST00000355805.2
ENST00000355432.3
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr16_-_31146961 0.11 ENST00000567531.1
protease, serine, 8
chr11_-_33774944 0.11 ENST00000532057.1
ENST00000531080.1
F-box protein 3
chr9_+_2017420 0.10 ENST00000439732.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_248031277 0.10 ENST00000537741.1
olfactory receptor, family 2, subfamily W, member 3
chr1_+_94883991 0.10 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr6_+_90272027 0.10 ENST00000522441.1
ankyrin repeat domain 6
chr11_+_61717842 0.10 ENST00000449131.2
bestrophin 1
chr16_-_55909272 0.09 ENST00000319165.9
carboxylesterase 5A
chr14_-_21493649 0.09 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG family member 2
chr15_+_32885657 0.09 ENST00000448387.2
ENST00000569659.1
golgin A8 family, member N
chr14_+_53173910 0.09 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr11_+_130029457 0.08 ENST00000278742.5
suppression of tumorigenicity 14 (colon carcinoma)
chr1_-_193075180 0.08 ENST00000367440.3
glutaredoxin 2
chr14_+_53173890 0.07 ENST00000445930.2
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr9_+_103189405 0.07 ENST00000395067.2
Myb/SANT-like DNA-binding domain containing 3
chr19_-_42636617 0.07 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU class 2 homeobox 2
chrX_+_103294483 0.07 ENST00000355016.3
H2B histone family, member M
chr13_-_114898016 0.06 ENST00000542651.1
ENST00000334062.7
RAS p21 protein activator 3
chr15_+_76135622 0.06 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
ubiquitin-conjugating enzyme E2Q family member 2
chr16_-_55909255 0.06 ENST00000290567.9
carboxylesterase 5A
chr12_-_123560608 0.06 ENST00000541244.1
phosphatidylinositol transfer protein, membrane-associated 2
chr2_-_224810070 0.05 ENST00000429915.1
ENST00000233055.4
WD repeat and FYVE domain containing 1
chr11_+_134855246 0.05 ENST00000597621.1
CDNA FLJ27342 fis, clone TST02993; Uncharacterized protein
chr19_+_44716678 0.05 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
zinc finger protein 227
chr10_-_101989315 0.05 ENST00000370397.7
conserved helix-loop-helix ubiquitous kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of ZSCAN4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.3 0.3 GO:0042732 D-xylose metabolic process(GO:0042732)
0.3 0.9 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 7.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.3 1.3 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.3 3.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.2 0.6 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.2 2.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 0.5 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0005997 xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.3 GO:2000417 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) negative regulation of eosinophil migration(GO:2000417)
0.1 0.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.4 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.4 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.6 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 1.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.5 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:2000110 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 3.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 3.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 1.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 3.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 1.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 1.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.8 GO:0044308 axonal spine(GO:0044308)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.5 GO:0045179 apical cortex(GO:0045179)
0.1 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.2 GO:0071565 nBAF complex(GO:0071565)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 4.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 4.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 7.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.3 1.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 5.0 GO:0019864 IgG binding(GO:0019864)
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 6.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.5 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 1.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 1.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.4 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 2.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.2 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.3 GO:0016918 retinal binding(GO:0016918)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 3.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 4.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.9 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.6 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.2 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 3.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions