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Illumina Body Map 2: averaged replicates
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Results for AAGGCAC
Z-value: 2.38
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miRNA associated with seed AAGGCAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-124-3p.1
|
MIMAT0000422 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_33793430 Show fit | 3.94 |
ENST00000498907.2
|
CCAAT/enhancer binding protein (C/EBP), alpha |
|
| chr1_+_31885963 Show fit | 3.87 |
ENST00000373709.3
|
serine incorporator 2 |
|
| chr5_+_75699040 Show fit | 3.20 |
ENST00000274364.6
|
IQ motif containing GTPase activating protein 2 |
|
| chr21_-_44846999 Show fit | 3.18 |
ENST00000270162.6
|
salt-inducible kinase 1 |
|
| chr11_+_76494253 Show fit | 3.17 |
ENST00000333090.4
|
tsukushi, small leucine rich proteoglycan |
|
| chr22_-_50746027 Show fit | 3.10 |
ENST00000425954.1
ENST00000449103.1 |
plexin B2 |
|
| chr17_+_6939362 Show fit | 3.05 |
ENST00000308027.6
|
solute carrier family 16, member 13 |
|
| chr15_+_91411810 Show fit | 2.93 |
ENST00000268171.3
|
furin (paired basic amino acid cleaving enzyme) |
|
| chr10_+_89419370 Show fit | 2.85 |
ENST00000361175.4
ENST00000456849.1 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
|
| chr9_+_137218362 Show fit | 2.84 |
ENST00000481739.1
|
retinoid X receptor, alpha |
Network of associatons between targets according to the STRING database.
First level regulatory network of AAGGCAC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.4 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 5.4 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 1.3 | 5.2 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.1 | 4.5 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 4.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.6 | 3.9 | GO:1904219 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.3 | 3.9 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 3.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 3.7 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.3 | 3.6 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.4 | GO:0005768 | endosome(GO:0005768) |
| 0.0 | 10.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 9.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 7.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.1 | 6.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 6.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 6.1 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.1 | 5.9 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 5.3 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 5.1 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.9 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.3 | 7.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 7.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 6.5 | GO:0061659 | ubiquitin-like protein ligase activity(GO:0061659) |
| 0.3 | 6.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 5.8 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 4.5 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 4.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 4.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 4.2 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 8.4 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 8.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 7.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 7.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 6.5 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.2 | 6.3 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 6.1 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 6.1 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 5.9 | PID LKB1 PATHWAY | LKB1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.7 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 7.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 7.0 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 6.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 5.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.3 | 4.5 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.2 | 4.4 | REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
| 0.2 | 4.3 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 4.3 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.1 | 3.9 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |